RIT2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: RIN belongs to the RAS (HRAS; MIM 190020) superfamily of small GTPases (Shao et al., 1999 [PubMed 10545207]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle exocytosis (GO:0016079)5.76483419
2vocalization behavior (GO:0071625)5.27232274
3neuron cell-cell adhesion (GO:0007158)5.26643100
4regulation of short-term neuronal synaptic plasticity (GO:0048172)5.25653710
5neurofilament cytoskeleton organization (GO:0060052)5.17947865
6auditory behavior (GO:0031223)5.09182650
7regulation of synaptic vesicle exocytosis (GO:2000300)4.62497693
8glutamate secretion (GO:0014047)4.62239065
9positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.60495602
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.58709611
11protein localization to synapse (GO:0035418)4.57359119
12response to auditory stimulus (GO:0010996)4.55841075
13neurotransmitter secretion (GO:0007269)4.54060983
14regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.47177764
15gamma-aminobutyric acid signaling pathway (GO:0007214)4.37302185
16positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.30163612
17regulation of glutamate receptor signaling pathway (GO:1900449)4.24350043
18negative regulation of cytosolic calcium ion concentration (GO:0051481)4.15317778
19cell migration in hindbrain (GO:0021535)4.14057770
20negative regulation of DNA recombination (GO:0045910)4.13036211
21synaptic vesicle maturation (GO:0016188)4.11170757
22mechanosensory behavior (GO:0007638)4.06109290
23neurotransmitter transport (GO:0006836)4.02919243
24regulation of synaptic vesicle transport (GO:1902803)4.01829975
25somatic hypermutation of immunoglobulin genes (GO:0016446)4.01302223
26somatic diversification of immune receptors via somatic mutation (GO:0002566)4.01302223
27neuron-neuron synaptic transmission (GO:0007270)3.99552473
28regulation of helicase activity (GO:0051095)3.94627043
29pyrimidine nucleobase catabolic process (GO:0006208)3.84638746
30dopamine transport (GO:0015872)3.84435612
31neurotransmitter-gated ion channel clustering (GO:0072578)3.84316299
32regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.83710104
33response to histamine (GO:0034776)3.83122794
34negative regulation of synaptic transmission, GABAergic (GO:0032229)3.82385528
35ionotropic glutamate receptor signaling pathway (GO:0035235)3.75981235
36regulation of neurotransmitter levels (GO:0001505)3.75165362
37neuronal action potential propagation (GO:0019227)3.74655850
38locomotory exploration behavior (GO:0035641)3.74593611
39glutamate receptor signaling pathway (GO:0007215)3.74192741
40mating behavior (GO:0007617)3.69499516
41dopamine biosynthetic process (GO:0042416)3.67912138
42presynaptic membrane assembly (GO:0097105)3.62713755
43energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.62517768
44ATP hydrolysis coupled proton transport (GO:0015991)3.62517768
45catecholamine transport (GO:0051937)3.61842928
46negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.59787735
47proline transport (GO:0015824)3.58842764
48exploration behavior (GO:0035640)3.58633033
49synaptic vesicle docking involved in exocytosis (GO:0016081)3.55245395
50synaptic transmission, glutamatergic (GO:0035249)3.54908590
51cerebellar granule cell differentiation (GO:0021707)3.53885031
52regulation of synapse maturation (GO:0090128)3.53222556
53positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.52185034
54striatum development (GO:0021756)3.50784726
55synaptic transmission, dopaminergic (GO:0001963)3.50331149
56righting reflex (GO:0060013)3.50068736
57positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.49596820
58synaptic vesicle endocytosis (GO:0048488)3.49253645
59behavioral response to cocaine (GO:0048148)3.47348446
60regulation of vesicle fusion (GO:0031338)3.46359756
61positive regulation of synapse maturation (GO:0090129)3.43713907
62G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.43219179
63neuron recognition (GO:0008038)3.39882726
64transferrin transport (GO:0033572)3.39846175
65positive regulation of synapse assembly (GO:0051965)3.38836883
66positive regulation of microtubule polymerization or depolymerization (GO:0031112)3.38711168
67long-term synaptic potentiation (GO:0060291)3.37465682
68neurotransmitter catabolic process (GO:0042135)3.37398174
69regulation of synaptic transmission, glutamatergic (GO:0051966)3.37027366
70membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.35705139
71presynaptic membrane organization (GO:0097090)3.35306071
72regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.35286801
73regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.35286801
74postsynaptic membrane organization (GO:0001941)3.33601706
75neuromuscular process controlling posture (GO:0050884)3.32815882
76regulation of glutamate secretion (GO:0014048)3.30831367
77synaptic vesicle transport (GO:0048489)3.30340434
78establishment of synaptic vesicle localization (GO:0097480)3.30340434
79regulation of excitatory postsynaptic membrane potential (GO:0060079)3.29161657
80regulation of protein kinase A signaling (GO:0010738)3.28386022
81startle response (GO:0001964)3.28103588
82transmission of nerve impulse (GO:0019226)3.27716720
83cerebellar Purkinje cell differentiation (GO:0021702)3.27555521
84gamma-aminobutyric acid transport (GO:0015812)3.27076553
85regulation of postsynaptic membrane potential (GO:0060078)3.26598081
86regulation of neurotransmitter secretion (GO:0046928)3.26320950
87neurotransmitter biosynthetic process (GO:0042136)3.24835058
88regulation of catecholamine metabolic process (GO:0042069)3.22389230
89regulation of dopamine metabolic process (GO:0042053)3.22389230
90regulation of neurotransmitter transport (GO:0051588)3.21674074
91synapse assembly (GO:0007416)3.20449580
92long-term memory (GO:0007616)3.19644747
93regulation of long-term neuronal synaptic plasticity (GO:0048169)3.18562862
94mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.17838215
95positive regulation of synaptic transmission, GABAergic (GO:0032230)3.17522205
96trivalent inorganic cation transport (GO:0072512)3.17264273
97ferric iron transport (GO:0015682)3.17264273
98behavioral response to ethanol (GO:0048149)3.15750460
99cellular potassium ion homeostasis (GO:0030007)3.15588354
100membrane hyperpolarization (GO:0060081)3.15555043
101regulation of synapse structural plasticity (GO:0051823)3.15143979
102prepulse inhibition (GO:0060134)3.13995672
103regulation of neuronal synaptic plasticity (GO:0048168)3.13755698
104nucleobase catabolic process (GO:0046113)3.11656750
105positive regulation of neurotransmitter transport (GO:0051590)3.09843350
106dendrite morphogenesis (GO:0048813)3.08917124
107negative regulation of dendrite development (GO:2000171)3.08554984
108cerebellar Purkinje cell layer development (GO:0021680)3.06623724
109regulation of synaptic transmission, dopaminergic (GO:0032225)3.05481468
110response to cocaine (GO:0042220)3.04518608
111membrane depolarization during action potential (GO:0086010)3.02742164
112* synaptic transmission (GO:0007268)3.02611185
113membrane depolarization (GO:0051899)3.02150813
114positive regulation of membrane potential (GO:0045838)3.00742665
115response to dietary excess (GO:0002021)3.00611883
116regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.00259457
117determination of adult lifespan (GO:0008340)2.99919031
118negative regulation of dendrite morphogenesis (GO:0050774)2.99586365
119layer formation in cerebral cortex (GO:0021819)2.98241901
120female mating behavior (GO:0060180)2.97862487
121fear response (GO:0042596)2.96824166
122intraspecies interaction between organisms (GO:0051703)2.95577298
123social behavior (GO:0035176)2.95577298
124DNA damage response, detection of DNA damage (GO:0042769)2.94498205
125regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.93590628
126behavioral defense response (GO:0002209)2.93207502
127neuronal action potential (GO:0019228)2.92386318
128neurotransmitter uptake (GO:0001504)2.90336475
129regulation of calcium ion-dependent exocytosis (GO:0017158)2.88865129
130adult behavior (GO:0030534)2.85975573
131neuromuscular synaptic transmission (GO:0007274)2.85722243
132central nervous system projection neuron axonogenesis (GO:0021952)2.84509190
133positive regulation of microtubule polymerization (GO:0031116)2.83445238
134detection of calcium ion (GO:0005513)2.81213463
135response to insecticide (GO:0017085)2.78434793
136response to amphetamine (GO:0001975)2.76411058
137neuromuscular process (GO:0050905)2.76396567
138regulation of NFAT protein import into nucleus (GO:0051532)2.74363218
139cochlea development (GO:0090102)2.74252040
140serotonin metabolic process (GO:0042428)2.73917049
141positive regulation of amino acid transport (GO:0051957)2.72761965
142behavioral fear response (GO:0001662)2.72163466
143regulation of respiratory system process (GO:0044065)2.72110624

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.44208440
2GBX2_23144817_ChIP-Seq_PC3_Human4.07196357
3TAF15_26573619_Chip-Seq_HEK293_Human3.09573899
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.08225188
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.96213258
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.87739861
7REST_21632747_ChIP-Seq_MESCs_Mouse2.67866200
8SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.54249641
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.52579177
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.50771018
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.47306644
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.47295911
13NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.44213286
14EZH2_27304074_Chip-Seq_ESCs_Mouse2.42976192
15EZH2_18974828_ChIP-Seq_MESCs_Mouse2.42012468
16RNF2_18974828_ChIP-Seq_MESCs_Mouse2.42012468
17SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.37611981
18RBPJ_22232070_ChIP-Seq_NCS_Mouse2.33541635
19SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.33260293
20* CTBP2_25329375_ChIP-Seq_LNCAP_Human2.32193910
21MTF2_20144788_ChIP-Seq_MESCs_Mouse2.30615278
22EED_16625203_ChIP-ChIP_MESCs_Mouse2.26571582
23CTBP1_25329375_ChIP-Seq_LNCAP_Human2.23356935
24REST_18959480_ChIP-ChIP_MESCs_Mouse2.20821208
25ZFP57_27257070_Chip-Seq_ESCs_Mouse2.19817045
26CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.09259191
27BMI1_23680149_ChIP-Seq_NPCS_Mouse2.08784630
28IKZF1_21737484_ChIP-ChIP_HCT116_Human2.05985134
29SUZ12_27294783_Chip-Seq_ESCs_Mouse2.04873253
30TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.03237767
31GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.02652425
32EZH2_27294783_Chip-Seq_ESCs_Mouse1.98983484
33* SMAD4_21799915_ChIP-Seq_A2780_Human1.88286960
34* RARB_27405468_Chip-Seq_BRAIN_Mouse1.87010067
35AR_21572438_ChIP-Seq_LNCaP_Human1.86624346
36RNF2_27304074_Chip-Seq_ESCs_Mouse1.86365478
37IGF1R_20145208_ChIP-Seq_DFB_Human1.86095219
38DROSHA_22980978_ChIP-Seq_HELA_Human1.85729599
39CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.84827380
40P300_19829295_ChIP-Seq_ESCs_Human1.84541578
41ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.71686956
42POU3F2_20337985_ChIP-ChIP_501MEL_Human1.70548587
43SALL1_21062744_ChIP-ChIP_HESCs_Human1.69230311
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.65553871
45CBX2_27304074_Chip-Seq_ESCs_Mouse1.62550573
46MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.61195330
47FUS_26573619_Chip-Seq_HEK293_Human1.60510343
48SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.56874165
49VDR_22108803_ChIP-Seq_LS180_Human1.56113257
50RNF2_27304074_Chip-Seq_NSC_Mouse1.53441762
51NR3C1_23031785_ChIP-Seq_PC12_Mouse1.49277788
52* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.48656191
53* PIAS1_25552417_ChIP-Seq_VCAP_Human1.46484592
54* SMAD3_21741376_ChIP-Seq_EPCs_Human1.43957118
55AR_25329375_ChIP-Seq_VCAP_Human1.42641296
56PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.40985499
57ZNF274_21170338_ChIP-Seq_K562_Hela1.40175393
58* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.37501626
59* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35831654
60ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.33354641
61SOX2_21211035_ChIP-Seq_LN229_Gbm1.33322145
62* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.33179350
63ER_23166858_ChIP-Seq_MCF-7_Human1.32610533
64* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.30699291
65RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.27926355
66TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.25364132
67SMAD_19615063_ChIP-ChIP_OVARY_Human1.24697658
68STAT3_23295773_ChIP-Seq_U87_Human1.23572089
69RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.21765312
70CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21060476
71ERG_21242973_ChIP-ChIP_JURKAT_Human1.19836423
72MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.18502177
73POU5F1_16153702_ChIP-ChIP_HESCs_Human1.17613594
74TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.14443330
75* JUN_21703547_ChIP-Seq_K562_Human1.13879312
76* TCF4_23295773_ChIP-Seq_U87_Human1.12638030
77LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12045723
78AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.11936611
79* RUNX2_22187159_ChIP-Seq_PCA_Human1.11600523
80MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.11356519
81P53_22127205_ChIP-Seq_FIBROBLAST_Human1.10830743
82STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.09988580
83CDX2_19796622_ChIP-Seq_MESCs_Mouse1.07205230
84FLI1_27457419_Chip-Seq_LIVER_Mouse1.06778327
85* PRDM14_20953172_ChIP-Seq_ESCs_Human1.05213523
86RING1B_27294783_Chip-Seq_ESCs_Mouse1.03770682
87BCAT_22108803_ChIP-Seq_LS180_Human1.03525147
88NANOG_18555785_Chip-Seq_ESCs_Mouse1.02998818
89TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.02036234
90FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.00852891
91KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.00381328
92RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.00338150
93* AR_19668381_ChIP-Seq_PC3_Human0.99193644
94GATA1_26923725_Chip-Seq_HPCs_Mouse0.99035867
95TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98087696
96MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.97594226
97* SOX9_26525672_Chip-Seq_HEART_Mouse0.97122983
98NR3C1_21868756_ChIP-Seq_MCF10A_Human0.94812870
99CBP_20019798_ChIP-Seq_JUKART_Human0.93704293
100IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.93704293
101KDM2B_26808549_Chip-Seq_REH_Human0.93098957
102* CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.92986300
103CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.92469499
104FLI1_21867929_ChIP-Seq_TH2_Mouse0.91751125
105EWS_26573619_Chip-Seq_HEK293_Human0.91456132
106MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.91066211
107YAP1_20516196_ChIP-Seq_MESCs_Mouse0.90339942
108PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.88882540
109ARNT_22903824_ChIP-Seq_MCF-7_Human0.87693975
110GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.87467081
111SMAD3_21741376_ChIP-Seq_ESCs_Human0.87348744
112EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.86829171
113POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.83470033
114TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83470033

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.99868608
2MP0004859_abnormal_synaptic_plasticity4.28766445
3MP0003635_abnormal_synaptic_transmissio3.61231011
4MP0009046_muscle_twitch3.42882861
5MP0002822_catalepsy3.32613221
6MP0009745_abnormal_behavioral_response3.29254342
7MP0006276_abnormal_autonomic_nervous3.21242495
8MP0002064_seizures3.14889246
9MP0001968_abnormal_touch/_nociception3.00656760
10MP0002063_abnormal_learning/memory/cond2.87182861
11MP0002572_abnormal_emotion/affect_behav2.77041390
12MP0001529_abnormal_vocalization2.76642525
13MP0004270_analgesia2.68999515
14MP0001501_abnormal_sleep_pattern2.66884794
15MP0002272_abnormal_nervous_system2.64058328
16MP0000566_synostosis2.56381127
17MP0002736_abnormal_nociception_after2.55511532
18MP0002734_abnormal_mechanical_nocicepti2.50478696
19MP0003122_maternal_imprinting2.47776058
20MP0001440_abnormal_grooming_behavior2.40638133
21MP0005423_abnormal_somatic_nervous2.37296543
22MP0001905_abnormal_dopamine_level2.33923047
23MP0001486_abnormal_startle_reflex2.30756987
24MP0002735_abnormal_chemical_nociception2.20554514
25MP0002067_abnormal_sensory_capabilities2.16093323
26MP0001984_abnormal_olfaction2.14366472
27MP0002733_abnormal_thermal_nociception2.01044949
28MP0004924_abnormal_behavior2.00895361
29MP0005386_behavior/neurological_phenoty2.00895361
30MP0005646_abnormal_pituitary_gland1.99315826
31MP0001970_abnormal_pain_threshold1.99240862
32MP0000569_abnormal_digit_pigmentation1.91106501
33MP0004142_abnormal_muscle_tone1.85303553
34MP0001188_hyperpigmentation1.84664126
35MP0004147_increased_porphyrin_level1.82552349
36MP0002184_abnormal_innervation1.81965362
37MP0002557_abnormal_social/conspecific_i1.76971049
38MP0003890_abnormal_embryonic-extraembry1.74055098
39MP0005645_abnormal_hypothalamus_physiol1.72305373
40MP0005551_abnormal_eye_electrophysiolog1.68874715
41MP0003787_abnormal_imprinting1.57211746
42MP0010386_abnormal_urinary_bladder1.55694883
43MP0002909_abnormal_adrenal_gland1.55213965
44MP0001502_abnormal_circadian_rhythm1.53068602
45MP0008569_lethality_at_weaning1.50170882
46MP0000778_abnormal_nervous_system1.42568156
47MP0002837_dystrophic_cardiac_calcinosis1.41438785
48MP0008872_abnormal_physiological_respon1.34818105
49MP0004811_abnormal_neuron_physiology1.34222606
50MP0002638_abnormal_pupillary_reflex1.33976500
51MP0002066_abnormal_motor_capabilities/c1.33613123
52MP0002882_abnormal_neuron_morphology1.31078196
53MP0003879_abnormal_hair_cell1.29861459
54MP0003329_amyloid_beta_deposits1.27028020
55MP0000955_abnormal_spinal_cord1.24612790
56MP0009780_abnormal_chondrocyte_physiolo1.23442408
57MP0000751_myopathy1.22745250
58MP0002876_abnormal_thyroid_physiology1.18742087
59MP0006072_abnormal_retinal_apoptosis1.13164250
60MP0002090_abnormal_vision1.12392617
61MP0004858_abnormal_nervous_system1.11965737
62MP0002229_neurodegeneration1.06711133
63MP0003633_abnormal_nervous_system1.03533776
64MP0005499_abnormal_olfactory_system1.02468426
65MP0005394_taste/olfaction_phenotype1.02468426
66MP0005535_abnormal_body_temperature1.02221334
67MP0004742_abnormal_vestibular_system0.98559652
68MP0000631_abnormal_neuroendocrine_gland0.98427520
69MP0003283_abnormal_digestive_organ0.95956836
70MP0001485_abnormal_pinna_reflex0.94795930
71MP0002152_abnormal_brain_morphology0.92050014
72MP0003631_nervous_system_phenotype0.91724000
73MP0003121_genomic_imprinting0.91311532
74MP0002069_abnormal_eating/drinking_beha0.90703650
75MP0002752_abnormal_somatic_nervous0.89892089
76MP0000013_abnormal_adipose_tissue0.89818492
77MP0002332_abnormal_exercise_endurance0.86841895
78MP0001963_abnormal_hearing_physiology0.85959135
79MP0000920_abnormal_myelination0.85634754
80MP0003137_abnormal_impulse_conducting0.84814342
81MP0002102_abnormal_ear_morphology0.84632565
82MP0004145_abnormal_muscle_electrophysio0.83687747
83MP0001664_abnormal_digestion0.83469534
84MP0003861_abnormal_nervous_system0.83149789
85MP0004085_abnormal_heartbeat0.82875476
86MP0004133_heterotaxia0.82625609
87MP0004215_abnormal_myocardial_fiber0.82125471
88MP0005187_abnormal_penis_morphology0.81445914
89MP0005409_darkened_coat_color0.78947655
90MP0008874_decreased_physiological_sensi0.77911170
91MP0004233_abnormal_muscle_weight0.77191844
92MP0005253_abnormal_eye_physiology0.76672170
93MP0003119_abnormal_digestive_system0.76152244
94MP0003136_yellow_coat_color0.71894706
95MP0004885_abnormal_endolymph0.70951377
96MP0010770_preweaning_lethality0.70787572
97MP0002082_postnatal_lethality0.70787572
98MP0002751_abnormal_autonomic_nervous0.70632787
99MP0003634_abnormal_glial_cell0.70441665
100MP0006035_abnormal_mitochondrial_morpho0.69951272
101MP0010769_abnormal_survival0.69903813
102MP0003690_abnormal_glial_cell0.69741267
103MP0010768_mortality/aging0.67711714
104MP0000049_abnormal_middle_ear0.67369451
105MP0003123_paternal_imprinting0.67327384
106MP0008877_abnormal_DNA_methylation0.64620583
107MP0003646_muscle_fatigue0.62959080
108MP0003698_abnormal_male_reproductive0.62541514
109MP0005379_endocrine/exocrine_gland_phen0.62376366
110MP0008875_abnormal_xenobiotic_pharmacok0.62141423
111MP0003632_abnormal_nervous_system0.61941308
112MP0003183_abnormal_peptide_metabolism0.61905026
113MP0001943_abnormal_respiration0.61508328
114MP0001986_abnormal_taste_sensitivity0.60048916
115MP0003011_delayed_dark_adaptation0.59845334
116MP0001177_atelectasis0.57399666
117MP0002081_perinatal_lethality0.56475810
118MP0000026_abnormal_inner_ear0.55247189
119MP0004484_altered_response_of0.54305175
120MP0002163_abnormal_gland_morphology0.53275964
121MP0000538_abnormal_urinary_bladder0.52110529
122MP0004036_abnormal_muscle_relaxation0.51456294
123MP0005195_abnormal_posterior_eye0.51046891
124MP0008789_abnormal_olfactory_epithelium0.51020605

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.87541606
2Agnosia (HP:0010524)6.20170601
3Ependymoma (HP:0002888)5.37649841
4Atonic seizures (HP:0010819)5.33377629
5Myokymia (HP:0002411)5.24445296
6Focal seizures (HP:0007359)4.94131304
7Limb dystonia (HP:0002451)4.82614625
8Febrile seizures (HP:0002373)4.76886938
9Epileptic encephalopathy (HP:0200134)4.74643985
10Astrocytoma (HP:0009592)4.68890908
11Abnormality of the astrocytes (HP:0100707)4.68890908
12Visual hallucinations (HP:0002367)4.63250644
13Medulloblastoma (HP:0002885)4.62033305
14Absence seizures (HP:0002121)4.55474135
15Progressive cerebellar ataxia (HP:0002073)4.10663911
16Glioma (HP:0009733)4.03672513
17Dialeptic seizures (HP:0011146)4.03429450
18Neoplasm of the oral cavity (HP:0100649)3.96405733
19Generalized tonic-clonic seizures (HP:0002069)3.83951255
20Hypothermia (HP:0002045)3.76905183
21Acute necrotizing encephalopathy (HP:0006965)3.45061100
22Pheochromocytoma (HP:0002666)3.44587667
23Hyperventilation (HP:0002883)3.44159899
24Rhabdomyosarcoma (HP:0002859)3.43897956
25Cerebral hypomyelination (HP:0006808)3.42006555
26Abnormal mitochondria in muscle tissue (HP:0008316)3.32854060
27Abnormal hair whorl (HP:0010721)3.24316002
28Polyphagia (HP:0002591)3.20635586
29Failure to thrive in infancy (HP:0001531)3.17309696
30Progressive macrocephaly (HP:0004481)3.16789879
31Neuroendocrine neoplasm (HP:0100634)3.16771253
32Gait imbalance (HP:0002141)3.11558910
33Abnormal eating behavior (HP:0100738)2.99504618
34Anxiety (HP:0000739)2.86493851
35Congenital primary aphakia (HP:0007707)2.85635199
36Biliary tract neoplasm (HP:0100574)2.85205137
37Progressive inability to walk (HP:0002505)2.84184068
38Mitochondrial inheritance (HP:0001427)2.83508363
39Medial flaring of the eyebrow (HP:0010747)2.81670910
40Broad-based gait (HP:0002136)2.81094946
41Amyotrophic lateral sclerosis (HP:0007354)2.79117098
42Amblyopia (HP:0000646)2.71420475
43Truncal ataxia (HP:0002078)2.70663460
44Gaze-evoked nystagmus (HP:0000640)2.68547986
45Poor suck (HP:0002033)2.65430452
46Nephrogenic diabetes insipidus (HP:0009806)2.63515188
47Volvulus (HP:0002580)2.63109543
48Cortical dysplasia (HP:0002539)2.59709115
49Dysdiadochokinesis (HP:0002075)2.59524554
50Acute encephalopathy (HP:0006846)2.57611866
51Neoplasm of striated muscle (HP:0009728)2.57430264
52Action tremor (HP:0002345)2.55128535
53Abnormality of the salivary glands (HP:0010286)2.53689795
54Hypoventilation (HP:0002791)2.51844034
55Depression (HP:0000716)2.50981510
56Abnormal pupillary function (HP:0007686)2.48811472
57Epileptiform EEG discharges (HP:0011182)2.47965187
58Genital tract atresia (HP:0001827)2.46118780
59Congenital stationary night blindness (HP:0007642)2.42971815
60Neoplasm of the rectum (HP:0100743)2.42451477
61Neoplasm of the small intestine (HP:0100833)2.41666448
62Vaginal atresia (HP:0000148)2.40021851
63Oligomenorrhea (HP:0000876)2.39451263
64Limb hypertonia (HP:0002509)2.38669627
65EEG with generalized epileptiform discharges (HP:0011198)2.37400111
66Optic disc pallor (HP:0000543)2.35496166
67Type II lissencephaly (HP:0007260)2.34923816
68Excessive salivation (HP:0003781)2.34735011
69Drooling (HP:0002307)2.34735011
70Increased CSF lactate (HP:0002490)2.32107227
71Supranuclear gaze palsy (HP:0000605)2.32052603
72Impaired vibration sensation in the lower limbs (HP:0002166)2.31387188
73Congenital sensorineural hearing impairment (HP:0008527)2.30666591
74Dysmetria (HP:0001310)2.29740975
75Hyperthyroidism (HP:0000836)2.29561283
76CNS hypomyelination (HP:0003429)2.28971012
77Pachygyria (HP:0001302)2.26462561
78Specific learning disability (HP:0001328)2.25577451
79Spastic tetraparesis (HP:0001285)2.25321637
80Ankle clonus (HP:0011448)2.24525576
81Esotropia (HP:0000565)2.23362385
82Narrow nasal bridge (HP:0000446)2.22777281
83Adenoma sebaceum (HP:0009720)2.21674891
84Angiofibromas (HP:0010615)2.21674891
85Lissencephaly (HP:0001339)2.18761219
86Hepatocellular necrosis (HP:0001404)2.18013386
87Mutism (HP:0002300)2.16518213
88Bradykinesia (HP:0002067)2.15863275
89Abnormal ciliary motility (HP:0012262)2.12717400
90Inability to walk (HP:0002540)2.11265366
91Hypsarrhythmia (HP:0002521)2.09864279
92Abnormality of binocular vision (HP:0011514)2.09157253
93Diplopia (HP:0000651)2.09157253
94Poor eye contact (HP:0000817)2.08666436
95Scanning speech (HP:0002168)2.08272820
96Neuroblastic tumors (HP:0004376)2.07468531
97Peripheral primitive neuroectodermal neoplasm (HP:0030067)2.07468531
98Neuroblastoma (HP:0003006)2.07468531
99Primitive neuroectodermal tumor (HP:0030065)2.07468531
100Impaired social interactions (HP:0000735)2.06929379
101Abnormal social behavior (HP:0012433)2.06929379
102Hypoplasia of the brainstem (HP:0002365)2.06898718
103Aplasia/Hypoplasia of the brainstem (HP:0007362)2.06898718
104Morphological abnormality of the pyramidal tract (HP:0002062)2.06790313
105Abnormality of the labia minora (HP:0012880)2.05142545
106Abnormality of the lower motor neuron (HP:0002366)2.04158446
107Poor coordination (HP:0002370)2.03366780
108Psychosis (HP:0000709)2.02673329
109Urinary bladder sphincter dysfunction (HP:0002839)2.02332941
110Cerebellar dysplasia (HP:0007033)1.99915041
111Agitation (HP:0000713)1.99282933
112Central scotoma (HP:0000603)1.99271775
113Abnormal gallbladder physiology (HP:0012438)1.98478404
114Cholecystitis (HP:0001082)1.98478404
115Hemiplegia (HP:0002301)1.98318717
116Fetal akinesia sequence (HP:0001989)1.96952254
117Aplasia/Hypoplasia of the tibia (HP:0005772)1.96797177
118Ulnar claw (HP:0001178)1.95516023
119Short tibia (HP:0005736)1.94506742
120Postural instability (HP:0002172)1.94131356
121Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.92487773
122Delayed gross motor development (HP:0002194)1.92132491
123Hemiparesis (HP:0001269)1.91560285
124Delusions (HP:0000746)1.91528312
125Abnormal biliary tract morphology (HP:0012440)1.90348427
126Urinary urgency (HP:0000012)1.89871802
127Postural tremor (HP:0002174)1.89443908
128Memory impairment (HP:0002354)1.89277212
129Abnormality of macular pigmentation (HP:0008002)1.87878979
130Status epilepticus (HP:0002133)1.87853856
131Absent speech (HP:0001344)1.86082413
132Optic nerve hypoplasia (HP:0000609)1.85353876
133Spastic gait (HP:0002064)1.84658449
134Abnormal respiratory motile cilium physiology (HP:0012261)1.84122016
135Torticollis (HP:0000473)1.83281114
136Insidious onset (HP:0003587)1.82498687
137Termporal pattern (HP:0011008)1.82498687
138Abnormality of the corticospinal tract (HP:0002492)1.81453124
139Cerebral inclusion bodies (HP:0100314)1.80937161
140Leukodystrophy (HP:0002415)1.80735562
141Aplasia/Hypoplasia of the lens (HP:0008063)1.79245144
142Generalized myoclonic seizures (HP:0002123)1.79037180
143Atrophy/Degeneration involving motor neurons (HP:0007373)1.77825896
144Focal dystonia (HP:0004373)1.77821813
145Neoplasm of the peripheral nervous system (HP:0100007)1.77603311
146Retinal dysplasia (HP:0007973)1.75753476
147Akinesia (HP:0002304)1.73218181
148Sleep apnea (HP:0010535)1.68972308
149Supernumerary spleens (HP:0009799)1.67462926
150Absent septum pellucidum (HP:0001331)1.67331090
151Basal cell carcinoma (HP:0002671)1.64481190
152Spastic tetraplegia (HP:0002510)1.64239013
153Abnormal lung lobation (HP:0002101)1.62130453
154Lower limb muscle weakness (HP:0007340)1.61610889
155Freckling (HP:0001480)1.61284953
156Fibrous tissue neoplasm (HP:0012316)1.60996359
157Malignant neoplasm of the central nervous system (HP:0100836)1.58192352

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.13808515
2MAP3K124.08304013
3NTRK33.93432351
4MAP3K43.65967045
5MAP4K23.64034228
6MAP2K73.24115001
7MAP3K92.69946845
8PNCK2.56446191
9MINK12.48512557
10EPHA42.44598143
11MAP2K42.35133213
12MARK12.21195063
13GRK52.10812987
14PAK42.02636441
15NTRK21.92508540
16ARAF1.90715511
17PLK21.84352484
18DYRK21.80457445
19CDK191.74509685
20NME11.60896069
21NTRK11.52119630
22PAK61.48931017
23ERBB31.45035681
24DAPK21.41838763
25MAPK131.39211785
26GRK71.35800459
27DAPK11.34308046
28TSSK61.33661038
29AKT31.32852676
30CAMK2A1.32796206
31PRKCG1.29890148
32ACVR1B1.29341931
33FES1.26730346
34CDK51.25177515
35OXSR11.24054908
36MAPKAPK51.22835267
37TNIK1.21040733
38PRPF4B1.20870196
39MKNK21.19871369
40ADRBK21.18144364
41KSR21.12947040
42CAMK1G1.09929427
43CAMK2B1.09375221
44RIPK41.09211004
45PHKG21.06329296
46PHKG11.06329296
47WEE11.02294907
48UHMK11.00359441
49CAMKK20.98918756
50LIMK10.97315807
51TNK20.97147084
52CSNK1G20.95661841
53SRPK10.93440424
54SGK2230.93109426
55SGK4940.93109426
56CAMK2D0.91942589
57PKN10.91816146
58CDK180.91572191
59CDK140.91354126
60SIK30.90034974
61SIK20.89505513
62KSR10.88599042
63CDK150.87286884
64PRKCE0.85718621
65TYRO30.84984942
66BMPR1B0.84960393
67CSNK1A1L0.84104697
68CLK10.82810948
69CSNK1G30.80345556
70DYRK1A0.79697240
71SGK20.79621581
72CAMK2G0.76958875
73CAMKK10.76868378
74STK380.76800991
75WNK30.76425760
76BRAF0.75573411
77ADRBK10.75323178
78CDK11A0.74819362
79MAP3K130.73136917
80FGR0.71689373
81PAK30.70670070
82PRKCZ0.70528636
83LATS20.68300192
84PTK2B0.66852422
85MUSK0.63760070
86BMPR20.63378208
87CSNK1D0.63330181
88MAPK150.63325049
89MYLK0.61713123
90CAMK10.61202015
91MAP3K100.61056838
92ALK0.60215908
93FER0.59338954
94PDK30.58040817
95PDK40.58040817
96STK110.54732723
97STK390.53070316
98MKNK10.50875891
99BCR0.50034390
100PINK10.49868981
101PRKACA0.49702862
102TRIM280.48627031
103MAP2K10.47471960
104SGK10.47035478
105RPS6KA20.45663120
106RET0.45317482
107ROCK20.44604655
108DYRK30.43976570
109PRKCH0.43257395
110CCNB10.42873220
111INSRR0.42509179
112NEK10.42436461
113PLK40.42178284
114WNK40.41986297
115LMTK20.41374591
116GRK60.41313856
117WNK10.41274013
118PRKG10.41093850
119MAPK40.40598848
120MAPK120.39910657
121VRK10.39908360
122SGK30.39149770
123CSNK1G10.38924560
124RPS6KA30.37199693
125CSNK1E0.36858535
126CDK30.36399765
127MAP3K10.36358176
128MAP3K60.35983185
129RAF10.35895706
130PRKCA0.35704413
131PLK30.35111901
132PRKCB0.34901159
133CSNK1A10.34346753
134CAMK40.29700427
135PRKACG0.29686623

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.38404706
2Synaptic vesicle cycle_Homo sapiens_hsa047214.08375483
3Collecting duct acid secretion_Homo sapiens_hsa049663.13600454
4GABAergic synapse_Homo sapiens_hsa047272.94020335
5Oxidative phosphorylation_Homo sapiens_hsa001902.87788377
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.84575905
7Morphine addiction_Homo sapiens_hsa050322.55794846
8Olfactory transduction_Homo sapiens_hsa047402.38015066
9Amphetamine addiction_Homo sapiens_hsa050312.37101781
10Parkinsons disease_Homo sapiens_hsa050122.34500285
11Circadian entrainment_Homo sapiens_hsa047132.30449653
12Dopaminergic synapse_Homo sapiens_hsa047282.16709410
13Glutamatergic synapse_Homo sapiens_hsa047242.11668899
14Serotonergic synapse_Homo sapiens_hsa047262.07519637
15Cocaine addiction_Homo sapiens_hsa050302.04718417
16Taste transduction_Homo sapiens_hsa047422.00482830
17Long-term potentiation_Homo sapiens_hsa047201.99527873
18Vibrio cholerae infection_Homo sapiens_hsa051101.89493761
19Alzheimers disease_Homo sapiens_hsa050101.88774367
20Salivary secretion_Homo sapiens_hsa049701.80492435
21Insulin secretion_Homo sapiens_hsa049111.76170646
22Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.75344354
23Cholinergic synapse_Homo sapiens_hsa047251.70658155
24Cardiac muscle contraction_Homo sapiens_hsa042601.68166755
25Renin secretion_Homo sapiens_hsa049241.67162386
26Long-term depression_Homo sapiens_hsa047301.61890195
27Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.60264606
28Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.58435966
29Huntingtons disease_Homo sapiens_hsa050161.47304858
30Calcium signaling pathway_Homo sapiens_hsa040201.41776039
31Gastric acid secretion_Homo sapiens_hsa049711.40516577
32Steroid biosynthesis_Homo sapiens_hsa001001.33100766
33Phototransduction_Homo sapiens_hsa047441.33099371
34Protein export_Homo sapiens_hsa030601.28999452
35Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.28725883
36Aldosterone synthesis and secretion_Homo sapiens_hsa049251.28478663
37Oxytocin signaling pathway_Homo sapiens_hsa049211.27452314
38Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.27043363
39Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.21453432
40Gap junction_Homo sapiens_hsa045401.14849632
41Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.12993962
42GnRH signaling pathway_Homo sapiens_hsa049121.04592590
43Mismatch repair_Homo sapiens_hsa034301.01987329
44Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.96132644
45Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.95944788
46Rheumatoid arthritis_Homo sapiens_hsa053230.94600030
47Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.92973807
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.92770980
49cAMP signaling pathway_Homo sapiens_hsa040240.87211892
50Ether lipid metabolism_Homo sapiens_hsa005650.84611406
51Linoleic acid metabolism_Homo sapiens_hsa005910.84068106
52Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.82385594
53Estrogen signaling pathway_Homo sapiens_hsa049150.80812372
54Basal transcription factors_Homo sapiens_hsa030220.77103493
55Vascular smooth muscle contraction_Homo sapiens_hsa042700.75349607
56Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.74335183
57Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.72698713
58Phosphatidylinositol signaling system_Homo sapiens_hsa040700.72484507
59alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.71121874
60cGMP-PKG signaling pathway_Homo sapiens_hsa040220.70706671
612-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.70025503
62Type I diabetes mellitus_Homo sapiens_hsa049400.65832137
63Type II diabetes mellitus_Homo sapiens_hsa049300.65812314
64Alcoholism_Homo sapiens_hsa050340.65187184
65Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.65081151
66Nitrogen metabolism_Homo sapiens_hsa009100.64064777
67Melanogenesis_Homo sapiens_hsa049160.63894557
68Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.63743407
69Axon guidance_Homo sapiens_hsa043600.63606663
70Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.62998618
71Phenylalanine metabolism_Homo sapiens_hsa003600.61805069
72Phagosome_Homo sapiens_hsa041450.61687683
73ErbB signaling pathway_Homo sapiens_hsa040120.60013626
74Pancreatic secretion_Homo sapiens_hsa049720.59950274
75Colorectal cancer_Homo sapiens_hsa052100.58686762
76Histidine metabolism_Homo sapiens_hsa003400.56589839
77Dilated cardiomyopathy_Homo sapiens_hsa054140.56095169
78Tyrosine metabolism_Homo sapiens_hsa003500.55719498
79Pyruvate metabolism_Homo sapiens_hsa006200.55099594
80Thyroid hormone synthesis_Homo sapiens_hsa049180.55024222
81Propanoate metabolism_Homo sapiens_hsa006400.54729874
82Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.53978586
83Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.52207663
84Oocyte meiosis_Homo sapiens_hsa041140.51592650
85RNA polymerase_Homo sapiens_hsa030200.49632075
86Circadian rhythm_Homo sapiens_hsa047100.47997189
87Vitamin B6 metabolism_Homo sapiens_hsa007500.47511664
88Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.47215003
89Glioma_Homo sapiens_hsa052140.46290696
90SNARE interactions in vesicular transport_Homo sapiens_hsa041300.46126492
91Butanoate metabolism_Homo sapiens_hsa006500.44563158
92MAPK signaling pathway_Homo sapiens_hsa040100.44168476
93Glucagon signaling pathway_Homo sapiens_hsa049220.43599650
94Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.43255413
95Arginine biosynthesis_Homo sapiens_hsa002200.42184212
96Dorso-ventral axis formation_Homo sapiens_hsa043200.38988112
97Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.35936090
98Phospholipase D signaling pathway_Homo sapiens_hsa040720.35886340
99beta-Alanine metabolism_Homo sapiens_hsa004100.35730540
100Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.34766643
101Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.34657631
102Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.34480895
103Inositol phosphate metabolism_Homo sapiens_hsa005620.34327441
104Ras signaling pathway_Homo sapiens_hsa040140.32387648
105Hippo signaling pathway_Homo sapiens_hsa043900.32110948
106Purine metabolism_Homo sapiens_hsa002300.31570095
107African trypanosomiasis_Homo sapiens_hsa051430.31342576
108Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.30630681
109Choline metabolism in cancer_Homo sapiens_hsa052310.27885265
110Ovarian steroidogenesis_Homo sapiens_hsa049130.26992414
111Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.25281262
112Glycerophospholipid metabolism_Homo sapiens_hsa005640.25061651
113Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.25032688
114Regulation of autophagy_Homo sapiens_hsa041400.24962120
115Hedgehog signaling pathway_Homo sapiens_hsa043400.24861743
116Prion diseases_Homo sapiens_hsa050200.24556264
117Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.24401239
118Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.21473755
119RNA degradation_Homo sapiens_hsa030180.20979517
120Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.18616963
121Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.18105125
122Bile secretion_Homo sapiens_hsa049760.16729580
123Renal cell carcinoma_Homo sapiens_hsa052110.14838842
124Sphingolipid signaling pathway_Homo sapiens_hsa040710.14182629
125Melanoma_Homo sapiens_hsa052180.13825946
126Rap1 signaling pathway_Homo sapiens_hsa040150.13639225

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