RGAG1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of male gonad development (GO:2000020)8.56834175
2cellular response to gonadotropin stimulus (GO:0071371)6.88632969
3regulation of male gonad development (GO:2000018)6.71794765
4negative regulation of metanephros development (GO:0072217)6.63512408
5cellular response to follicle-stimulating hormone stimulus (GO:0071372)5.89306052
6glomerulus development (GO:0032835)5.88033235
7negative regulation of mesenchymal cell apoptotic process (GO:2001054)5.76845173
8synaptic vesicle maturation (GO:0016188)5.62148050
9diaphragm development (GO:0060539)5.39735304
10regulation of short-term neuronal synaptic plasticity (GO:0048172)5.37830271
11skeletal muscle organ development (GO:0060538)5.36100154
12male genitalia development (GO:0030539)5.24813674
13locomotory exploration behavior (GO:0035641)5.19442171
14hemoglobin metabolic process (GO:0020027)5.11757289
15regulation of female gonad development (GO:2000194)5.08400972
16positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.04417791
17regulation of cardioblast differentiation (GO:0051890)5.02781606
18exploration behavior (GO:0035640)4.92295978
19epithelial cell differentiation involved in kidney development (GO:0035850)4.85762903
20response to gonadotropin (GO:0034698)4.76512861
21SMAD protein signal transduction (GO:0060395)4.75435630
22synaptic vesicle exocytosis (GO:0016079)4.57864964
23glutamate secretion (GO:0014047)4.52148228
24mesenchymal to epithelial transition (GO:0060231)4.46705063
25response to follicle-stimulating hormone (GO:0032354)4.43736633
26muscle cell fate commitment (GO:0042693)4.42328630
27regulation of mesenchymal cell apoptotic process (GO:2001053)4.41465852
28cardiac muscle hypertrophy in response to stress (GO:0014898)4.38179435
29muscle hypertrophy in response to stress (GO:0003299)4.38179435
30cardiac muscle adaptation (GO:0014887)4.38179435
31regulation of synaptic vesicle exocytosis (GO:2000300)4.33325610
32regulation of gonadotropin secretion (GO:0032276)4.28894723
33negative regulation of kidney development (GO:0090185)4.27198909
34positive regulation of mesonephros development (GO:0061213)4.18004411
35reproductive system development (GO:0061458)4.17882991
36vocalization behavior (GO:0071625)4.17434734
37layer formation in cerebral cortex (GO:0021819)4.14077034
38positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.11402575
39proline transport (GO:0015824)4.00673666
40synaptic vesicle docking involved in exocytosis (GO:0016081)3.96908250
41positive regulation of heart growth (GO:0060421)3.92395885
42short-chain fatty acid metabolic process (GO:0046459)3.90447224
43regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.90023172
44neurotransmitter secretion (GO:0007269)3.87790597
45regulation of transforming growth factor beta2 production (GO:0032909)3.86392262
46regulation of glutamate receptor signaling pathway (GO:1900449)3.83384549
47protein localization to synapse (GO:0035418)3.82624821
48mesonephros development (GO:0001823)3.82577829
49regulation of synapse structural plasticity (GO:0051823)3.82448841
50sodium ion export (GO:0071436)3.79368388
51neuron cell-cell adhesion (GO:0007158)3.78343998
52regulation of neuronal synaptic plasticity (GO:0048168)3.76699104
53endocardial cushion development (GO:0003197)3.76001666
54dendrite morphogenesis (GO:0048813)3.73619459
55sex determination (GO:0007530)3.73074814
56regulation of synaptic vesicle transport (GO:1902803)3.72265834
57embryonic foregut morphogenesis (GO:0048617)3.71999674
58cell migration in hindbrain (GO:0021535)3.71895574
59neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)3.69941836
60glomerular basement membrane development (GO:0032836)3.68123752
61regulation of long-term neuronal synaptic plasticity (GO:0048169)3.67184408
62positive regulation of synaptic transmission, GABAergic (GO:0032230)3.64045873
63activation of protein kinase A activity (GO:0034199)3.63171054
64androgen biosynthetic process (GO:0006702)3.58833282
65cellular potassium ion homeostasis (GO:0030007)3.58475288
66regulation of cell proliferation involved in kidney development (GO:1901722)3.57693946
67response to parathyroid hormone (GO:0071107)3.52543971
68regulation of glomerulus development (GO:0090192)3.44797094
69fusion of sperm to egg plasma membrane (GO:0007342)3.43692256
70axonal fasciculation (GO:0007413)3.43669161
71protein-chromophore linkage (GO:0018298)3.42937332
72cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.42066538
73regulation of mesonephros development (GO:0061217)3.40351385
74response to BMP (GO:0071772)3.37627127
75cellular response to BMP stimulus (GO:0071773)3.37627127
76cell communication by electrical coupling (GO:0010644)3.37517857
77dendritic spine morphogenesis (GO:0060997)3.37125458
78neuron recognition (GO:0008038)3.35232508
79gamma-aminobutyric acid transport (GO:0015812)3.34549197
80cardiac muscle hypertrophy (GO:0003300)3.33976604
81notochord development (GO:0030903)3.30751206
82cellular sodium ion homeostasis (GO:0006883)3.30695887
83positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.30477872
84postsynaptic membrane organization (GO:0001941)3.30453268
85fibroblast migration (GO:0010761)3.29276108
86nephron tubule formation (GO:0072079)3.26935637
87pyrimidine nucleotide catabolic process (GO:0006244)3.26369029
88ionotropic glutamate receptor signaling pathway (GO:0035235)3.26240947
89negative regulation of macrophage differentiation (GO:0045650)3.25106500
90pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.25103048
91positive regulation of metanephros development (GO:0072216)3.25056999
92seminiferous tubule development (GO:0072520)3.24001709
93atrial septum morphogenesis (GO:0060413)3.20607418
94response to pheromone (GO:0019236)3.20005061
95regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.19781156
96sex differentiation (GO:0007548)3.16494232
97regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.15940515
98atrioventricular valve morphogenesis (GO:0003181)3.14771531
99striated muscle hypertrophy (GO:0014897)3.13697546
100innervation (GO:0060384)3.13561257
101regulation of metanephros development (GO:0072215)3.11782288
102cardiac right ventricle morphogenesis (GO:0003215)3.11474760
103glucocorticoid biosynthetic process (GO:0006704)3.06029404
104neuromuscular process controlling balance (GO:0050885)3.04858349
105cell migration involved in sprouting angiogenesis (GO:0002042)3.03970595
106vesicle transport along microtubule (GO:0047496)3.02655942
107regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.99386732
108neurotransmitter transport (GO:0006836)2.99277854
109organelle transport along microtubule (GO:0072384)2.98290887
110glutamate receptor signaling pathway (GO:0007215)2.96733634
111regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:00033392.96140966
112phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.95830779
113metanephric epithelium development (GO:0072207)2.93068882
114regulation of vesicle fusion (GO:0031338)2.91777120
115axon extension (GO:0048675)2.90144938
116synaptic vesicle endocytosis (GO:0048488)2.88226741
117cell differentiation involved in kidney development (GO:0061005)2.85596510
118dopamine receptor signaling pathway (GO:0007212)2.84179884
119synaptic transmission, glutamatergic (GO:0035249)2.84095871
120membrane depolarization during action potential (GO:0086010)2.83426566
121regulation of neurotransmitter secretion (GO:0046928)2.82946320
122long-term memory (GO:0007616)2.81319578
123membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.80929138
124central nervous system projection neuron axonogenesis (GO:0021952)2.80857242
125DNA demethylation (GO:0080111)2.80807666
126response to auditory stimulus (GO:0010996)2.80709765
127regulation of dendritic spine morphogenesis (GO:0061001)2.79182860
128negative regulation of reproductive process (GO:2000242)2.79175346
129regulation of neurotransmitter levels (GO:0001505)2.79115707
130protein insertion into membrane (GO:0051205)2.76904437
131cerebellar Purkinje cell differentiation (GO:0021702)2.76837857
132axon cargo transport (GO:0008088)2.76572903
133positive regulation of potassium ion transmembrane transport (GO:1901381)2.75474726
134regulation of synaptic transmission, GABAergic (GO:0032228)2.74578832
135positive regulation of organ growth (GO:0046622)2.73020387
136auditory behavior (GO:0031223)2.72979609
137clathrin coat assembly (GO:0048268)2.72618591
138negative regulation of sodium ion transport (GO:0010766)2.72509870
139neuron-neuron synaptic transmission (GO:0007270)2.72356052
140metanephric mesenchyme development (GO:0072075)2.72254549
141branching involved in ureteric bud morphogenesis (GO:0001658)2.72090352
142genitalia development (GO:0048806)2.71985557
143positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.71445659
144respiratory system process (GO:0003016)2.71312402
145negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.71283533
146regulation of excitatory postsynaptic membrane potential (GO:0060079)2.69431922
147mitochondrion transport along microtubule (GO:0047497)2.68744999
148establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.68744999
149cell communication involved in cardiac conduction (GO:0086065)2.68492779
150establishment of nucleus localization (GO:0040023)2.67841736
151regulation of synaptic plasticity (GO:0048167)2.67039782
152regulation of neurotransmitter transport (GO:0051588)2.66849151
153prepulse inhibition (GO:0060134)2.66356094
154estrogen biosynthetic process (GO:0006703)2.65033149
155neuromuscular process controlling posture (GO:0050884)2.64768940
156anterior/posterior axis specification, embryo (GO:0008595)2.64689202
157female gonad development (GO:0008585)2.63397769
158regulation of cAMP-dependent protein kinase activity (GO:2000479)2.63387809
159oxidative demethylation (GO:0070989)2.63092428
160neurotransmitter-gated ion channel clustering (GO:0072578)2.62739225
161negative regulation of microtubule polymerization (GO:0031115)2.62340918
162apical protein localization (GO:0045176)2.62201763
163positive regulation of axon extension (GO:0045773)2.62126115
164synapse assembly (GO:0007416)2.62113574
165regulation of chromatin binding (GO:0035561)2.58902583
166adrenal gland development (GO:0030325)2.58143074
167gastrulation with mouth forming second (GO:0001702)2.57891445
168limb bud formation (GO:0060174)2.57673653
169endothelial cell chemotaxis (GO:0035767)2.57590246
170adhesion of symbiont to host (GO:0044406)2.57547432
171muscle hypertrophy (GO:0014896)2.57174566
172kidney mesenchyme development (GO:0072074)2.57066739
173dermatan sulfate biosynthetic process (GO:0030208)2.56642834
174synapse organization (GO:0050808)2.56452030
175cellular response to epinephrine stimulus (GO:0071872)2.56431488
176regulation of postsynaptic membrane potential (GO:0060078)2.56379130
177pyrimidine nucleobase catabolic process (GO:0006208)2.56185524
178adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.55661642
179developmental cell growth (GO:0048588)2.55510461
180neuron projection extension (GO:1990138)2.55143040
181plasma membrane fusion (GO:0045026)2.54143165
182membrane repolarization (GO:0086009)2.53351605
183negative regulation of synaptic transmission, GABAergic (GO:0032229)2.52648375
184neuromuscular process (GO:0050905)2.52560972
185cerebellar Purkinje cell layer development (GO:0021680)2.52558451
186regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.52484620
187membrane hyperpolarization (GO:0060081)2.52378202
188regulation of ARF protein signal transduction (GO:0032012)2.52162984
189male gonad development (GO:0008584)2.49708912
190metanephros development (GO:0001656)2.49084386
191short-term memory (GO:0007614)2.48437945
192regulation of kidney development (GO:0090183)2.47510128

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.04330802
2SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.02345270
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.00966905
4GBX2_23144817_ChIP-Seq_PC3_Human2.94126529
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.87502918
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.84412654
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.84412654
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.82598682
9RBPJ_22232070_ChIP-Seq_NCS_Mouse2.74713309
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.73304525
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.67603466
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.65307318
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.59847871
14EED_16625203_ChIP-ChIP_MESCs_Mouse2.58184971
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.55918712
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.54805447
17ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.52239715
18MTF2_20144788_ChIP-Seq_MESCs_Mouse2.43402603
19DROSHA_22980978_ChIP-Seq_HELA_Human2.32806762
20SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.30380340
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.24022761
22AR_21572438_ChIP-Seq_LNCaP_Human2.21981183
23RNF2_27304074_Chip-Seq_NSC_Mouse2.16660436
24EZH2_27294783_Chip-Seq_ESCs_Mouse2.07681233
25SUZ12_27294783_Chip-Seq_ESCs_Mouse2.04361138
26REST_21632747_ChIP-Seq_MESCs_Mouse1.99473948
27HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.92188930
28RARB_27405468_Chip-Seq_BRAIN_Mouse1.91756876
29WT1_19549856_ChIP-ChIP_CCG9911_Human1.88301372
30CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.86917332
31EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.84366778
32NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.81245089
33PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.69446044
34MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.69431367
35PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.67078478
36WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.64789305
37RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.62378667
38REST_18959480_ChIP-ChIP_MESCs_Mouse1.61555111
39SMAD4_21799915_ChIP-Seq_A2780_Human1.60453660
40NR3C1_23031785_ChIP-Seq_PC12_Mouse1.60108042
41ERG_21242973_ChIP-ChIP_JURKAT_Human1.59381506
42ZNF274_21170338_ChIP-Seq_K562_Hela1.58608367
43CTBP2_25329375_ChIP-Seq_LNCAP_Human1.52075731
44IKZF1_21737484_ChIP-ChIP_HCT116_Human1.51888690
45SMAD_19615063_ChIP-ChIP_OVARY_Human1.47629326
46POU5F1_16153702_ChIP-ChIP_HESCs_Human1.44947635
47ZFP281_18757296_ChIP-ChIP_E14_Mouse1.41843571
48SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39723303
49SOX2_21211035_ChIP-Seq_LN229_Gbm1.39255841
50SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.38578308
51WT1_25993318_ChIP-Seq_PODOCYTE_Human1.38362889
52ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.38177363
53RING1B_27294783_Chip-Seq_ESCs_Mouse1.35655798
54CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.30643422
55TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.27604987
56GATA1_26923725_Chip-Seq_HPCs_Mouse1.27353856
57* AR_19668381_ChIP-Seq_PC3_Human1.26266857
58ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.24965407
59CBX2_27304074_Chip-Seq_ESCs_Mouse1.23917062
60OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23889099
61STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.22909938
62SMAD3_21741376_ChIP-Seq_EPCs_Human1.22758732
63RING1B_27294783_Chip-Seq_NPCs_Mouse1.22723470
64DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.22112284
65DNAJC2_21179169_ChIP-ChIP_NT2_Human1.21619089
66TAF15_26573619_Chip-Seq_HEK293_Human1.21437095
67ZNF217_24962896_ChIP-Seq_MCF-7_Human1.21388955
68YAP1_20516196_ChIP-Seq_MESCs_Mouse1.19565000
69P300_19829295_ChIP-Seq_ESCs_Human1.19461298
70STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.19159988
71CDX2_19796622_ChIP-Seq_MESCs_Mouse1.18284210
72TOP2B_26459242_ChIP-Seq_MCF-7_Human1.17641376
73KDM2B_26808549_Chip-Seq_K562_Human1.16965553
74EP300_21415370_ChIP-Seq_HL-1_Mouse1.16895364
75SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.16406859
76AR_25329375_ChIP-Seq_VCAP_Human1.15701892
77TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.14274623
78STAT3_23295773_ChIP-Seq_U87_Human1.14011569
79TP53_16413492_ChIP-PET_HCT116_Human1.12923496
80UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.12797667
81TP53_20018659_ChIP-ChIP_R1E_Mouse1.12449039
82EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.12210571
83SMAD4_21741376_ChIP-Seq_HESCs_Human1.11895170
84CTBP1_25329375_ChIP-Seq_LNCAP_Human1.11652595
85AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.11605582
86IGF1R_20145208_ChIP-Seq_DFB_Human1.11403929
87SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.11292778
88NR3C1_21868756_ChIP-Seq_MCF10A_Human1.11181492
89TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.10046864
90AHR_22903824_ChIP-Seq_MCF-7_Human1.09023043
91EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.08698802
92POU3F2_20337985_ChIP-ChIP_501MEL_Human1.07426242
93FUS_26573619_Chip-Seq_HEK293_Human1.07270524
94ESR1_20079471_ChIP-ChIP_T-47D_Human1.07097860
95NRF2_20460467_ChIP-Seq_MEFs_Mouse1.07067829
96NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.07067829
97RXR_22108803_ChIP-Seq_LS180_Human1.06977494
98PIAS1_25552417_ChIP-Seq_VCAP_Human1.06091407
99FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.05785884
100TRIM28_21343339_ChIP-Seq_HEK293_Human1.05632822
101ARNT_22903824_ChIP-Seq_MCF-7_Human1.05032775
102IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.04958310
103CBP_20019798_ChIP-Seq_JUKART_Human1.04958310
104TP53_18474530_ChIP-ChIP_U2OS_Human1.03633356
105BMI1_23680149_ChIP-Seq_NPCS_Mouse1.03363928
106TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.03333781
107ZFP281_27345836_Chip-Seq_ESCs_Mouse1.01455928
108ZFP57_27257070_Chip-Seq_ESCs_Mouse1.00837679
109ISL1_27105846_Chip-Seq_CPCs_Mouse0.98918471
110STAT6_21828071_ChIP-Seq_BEAS2B_Human0.97634583
111CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.97016747
112SALL1_21062744_ChIP-ChIP_HESCs_Human0.96904062
113SMAD3_21741376_ChIP-Seq_HESCs_Human0.96828848
114ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.96681866
115FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.96585113
116SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.96115111
117* SMAD4_21741376_ChIP-Seq_EPCs_Human0.95962831
118P53_22127205_ChIP-Seq_FIBROBLAST_Human0.95542643
119OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.95424174
120TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.95093200
121ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.95042855
122MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.94805907
123TCF4_23295773_ChIP-Seq_U87_Human0.93758698
124CTNNB1_20460455_ChIP-Seq_HCT116_Human0.93597489
125IRF1_19129219_ChIP-ChIP_H3396_Human0.93107991
126SMAD3_21741376_ChIP-Seq_ESCs_Human0.92918059
127SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.92773705
128VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.92459763
129KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.91897310
130POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.91231883
131TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91231883
132TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90443985
133KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.87683644
134TBX3_20139965_ChIP-Seq_ESCs_Mouse0.86965048
135TBX3_20139965_ChIP-Seq_MESCs_Mouse0.86916634
136SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.86824444
137MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.86013327
138TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.85731444
139TBL1_22424771_ChIP-Seq_293T_Human0.85428220
140SALL4_18804426_ChIP-ChIP_XEN_Mouse0.85399924

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.54855327
2MP0008995_early_reproductive_senescence4.14447600
3MP0004270_analgesia3.88465846
4MP0003635_abnormal_synaptic_transmissio3.31176127
5MP0003122_maternal_imprinting3.25153037
6MP0001968_abnormal_touch/_nociception3.20576782
7MP0003828_pulmonary_edema3.06614652
8MP0000537_abnormal_urethra_morphology3.03703775
9MP0000569_abnormal_digit_pigmentation2.85008685
10MP0002735_abnormal_chemical_nociception2.81458425
11MP0002734_abnormal_mechanical_nocicepti2.78386310
12MP0003880_abnormal_central_pattern2.68333114
13MP0002736_abnormal_nociception_after2.54264462
14MP0004858_abnormal_nervous_system2.54157827
15MP0002063_abnormal_learning/memory/cond2.47968942
16MP0009384_cardiac_valve_regurgitation2.47701680
17MP0008877_abnormal_DNA_methylation2.44395361
18MP0000639_abnormal_adrenal_gland2.43845385
19MP0009745_abnormal_behavioral_response2.36303350
20MP0009046_muscle_twitch2.30399114
21MP0005423_abnormal_somatic_nervous2.29752443
22MP0003315_abnormal_perineum_morphology2.25826575
23MP0004133_heterotaxia2.24099240
24MP0002064_seizures2.18113054
25MP0006276_abnormal_autonomic_nervous2.13664226
26MP0001661_extended_life_span2.07527942
27MP0002733_abnormal_thermal_nociception2.07378992
28MP0009780_abnormal_chondrocyte_physiolo2.05508673
29MP0002572_abnormal_emotion/affect_behav1.98880186
30MP0005503_abnormal_tendon_morphology1.98835271
31MP0002102_abnormal_ear_morphology1.96770140
32MP0001970_abnormal_pain_threshold1.93951163
33MP0002272_abnormal_nervous_system1.89596103
34MP0002184_abnormal_innervation1.88867136
35MP0000778_abnormal_nervous_system1.85780472
36MP0001299_abnormal_eye_distance/1.84245707
37MP0003195_calcinosis1.81726795
38MP0000534_abnormal_ureter_morphology1.75638654
39MP0008004_abnormal_stomach_pH1.75333827
40MP0000749_muscle_degeneration1.72383712
41MP0004811_abnormal_neuron_physiology1.71926434
42MP0001486_abnormal_startle_reflex1.69647578
43MP0003119_abnormal_digestive_system1.66715721
44MP0003123_paternal_imprinting1.64718666
45MP0000955_abnormal_spinal_cord1.64151854
46MP0003115_abnormal_respiratory_system1.64134799
47MP0005367_renal/urinary_system_phenotyp1.59315720
48MP0000516_abnormal_urinary_system1.59315720
49MP0004233_abnormal_muscle_weight1.56506501
50MP0003942_abnormal_urinary_system1.55607767
51MP0002067_abnormal_sensory_capabilities1.52456657
52MP0000751_myopathy1.51698660
53MP0001501_abnormal_sleep_pattern1.46040686
54MP0002822_catalepsy1.45902070
55MP0005623_abnormal_meninges_morphology1.43099320
56MP0003567_abnormal_fetal_cardiomyocyte1.38901483
57MP0002557_abnormal_social/conspecific_i1.37010587
58MP0003121_genomic_imprinting1.35487668
59MP0001919_abnormal_reproductive_system1.34415063
60MP0010030_abnormal_orbit_morphology1.34374078
61MP0003879_abnormal_hair_cell1.34337621
62MP0004924_abnormal_behavior1.29512386
63MP0005386_behavior/neurological_phenoty1.29512386
64MP0002909_abnormal_adrenal_gland1.29245483
65MP0003329_amyloid_beta_deposits1.27833357
66MP0002882_abnormal_neuron_morphology1.25384824
67MP0005389_reproductive_system_phenotype1.25093021
68MP0008569_lethality_at_weaning1.24252209
69MP0002127_abnormal_cardiovascular_syste1.23669171
70MP0001440_abnormal_grooming_behavior1.23570792
71MP0004885_abnormal_endolymph1.23210451
72MP0001348_abnormal_lacrimal_gland1.21619001
73MP0003385_abnormal_body_wall1.19698138
74MP0002638_abnormal_pupillary_reflex1.18723533
75MP0001188_hyperpigmentation1.17826734
76MP0003221_abnormal_cardiomyocyte_apopto1.12876131
77MP0000462_abnormal_digestive_system1.10283222
78MP0009250_abnormal_appendicular_skeleto1.09205785
79MP0001270_distended_abdomen1.09134414
80MP0002249_abnormal_larynx_morphology1.09122196
81MP0004145_abnormal_muscle_electrophysio1.09071673
82MP0002066_abnormal_motor_capabilities/c1.07098077
83MP0001542_abnormal_bone_strength1.05144710
84MP0003283_abnormal_digestive_organ1.05106169
85MP0003787_abnormal_imprinting1.03211964
86MP0004134_abnormal_chest_morphology1.03000618
87MP0004742_abnormal_vestibular_system1.01165937
88MP0002837_dystrophic_cardiac_calcinosis0.98674274
89MP0008438_abnormal_cutaneous_collagen0.98365574
90MP0002152_abnormal_brain_morphology0.98324714
91MP0001984_abnormal_olfaction0.96714280
92MP0005646_abnormal_pituitary_gland0.96267332
93MP0003935_abnormal_craniofacial_develop0.96175557
94MP0001177_atelectasis0.96038043
95MP0003633_abnormal_nervous_system0.95828071
96MP0005508_abnormal_skeleton_morphology0.95459088
97MP0003011_delayed_dark_adaptation0.94469550
98MP0005410_abnormal_fertilization0.93935437
99MP0002114_abnormal_axial_skeleton0.93653208
100MP0010368_abnormal_lymphatic_system0.93175556
101MP0002089_abnormal_postnatal_growth/wei0.92826377
102MP0008961_abnormal_basal_metabolism0.89722689
103MP0005645_abnormal_hypothalamus_physiol0.89287439
104MP0002108_abnormal_muscle_morphology0.88992498
105MP0002896_abnormal_bone_mineralization0.88906382
106MP0006138_congestive_heart_failure0.86983993
107MP0003656_abnormal_erythrocyte_physiolo0.84154704
108MP0000579_abnormal_nail_morphology0.83820550
109MP0003045_fibrosis0.80554731
110MP0002160_abnormal_reproductive_system0.80151546
111MP0004272_abnormal_basement_membrane0.79878320
112MP0003755_abnormal_palate_morphology0.79813023
113MP0002332_abnormal_exercise_endurance0.79560332
114MP0000013_abnormal_adipose_tissue0.79400441
115MP0004215_abnormal_myocardial_fiber0.79253467
116MP0001119_abnormal_female_reproductive0.79048626
117MP0003631_nervous_system_phenotype0.78883474
118MP0004484_altered_response_of0.78876300
119MP0005220_abnormal_exocrine_pancreas0.78075941
120MP0001727_abnormal_embryo_implantation0.77850596
121MP0005248_abnormal_Harderian_gland0.77173660
122MP0000653_abnormal_sex_gland0.76960253
123MP0001529_abnormal_vocalization0.76949129
124MP0003936_abnormal_reproductive_system0.76685735
125MP0000750_abnormal_muscle_regeneration0.76402976
126MP0003705_abnormal_hypodermis_morpholog0.75868922
127MP0002229_neurodegeneration0.75070956
128MP0001943_abnormal_respiration0.74943824
129MP0000759_abnormal_skeletal_muscle0.74874240
130MP0005187_abnormal_penis_morphology0.74170743
131MP0004085_abnormal_heartbeat0.72658617
132MP0002128_abnormal_blood_circulation0.72630803
133MP0001145_abnormal_male_reproductive0.71881460
134MP0003634_abnormal_glial_cell0.71009309
135MP0002090_abnormal_vision0.70772482
136MP0002069_abnormal_eating/drinking_beha0.70555130
137MP0000631_abnormal_neuroendocrine_gland0.69678046
138MP0003861_abnormal_nervous_system0.69342780
139MP0005275_abnormal_skin_tensile0.67290021
140MP0004142_abnormal_muscle_tone0.66531180
141MP0003279_aneurysm0.65249216
142MP0000428_abnormal_craniofacial_morphol0.64816677
143MP0005409_darkened_coat_color0.64775660
144MP0003137_abnormal_impulse_conducting0.64663498
145MP0000049_abnormal_middle_ear0.64224994
146MP0002081_perinatal_lethality0.62391458
147MP0002752_abnormal_somatic_nervous0.62375603
148MP0002116_abnormal_craniofacial_bone0.61822582
149MP0002751_abnormal_autonomic_nervous0.61041349

Predicted human phenotypes

RankGene SetZ-score
1Anomalous pulmonary venous return (HP:0010772)6.88781760
2Diaphragmatic weakness (HP:0009113)6.38714828
3Abnormality of the pulmonary veins (HP:0011718)6.23707713
4Gonadal dysgenesis (HP:0000133)6.03617992
5Myokymia (HP:0002411)5.07754151
6Testicular neoplasm (HP:0010788)5.05606656
7Dry hair (HP:0011359)4.75666653
8Stridor (HP:0010307)4.62115234
9Transposition of the great arteries (HP:0001669)4.58380272
10Abnormal connection of the cardiac segments (HP:0011545)4.58380272
11Abnormal ventriculo-arterial connection (HP:0011563)4.58380272
12Mesangial abnormality (HP:0001966)4.39727470
13Hand muscle atrophy (HP:0009130)4.39327943
14Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.38463526
15Degeneration of the lateral corticospinal tracts (HP:0002314)4.38463526
16Hypoplastic left heart (HP:0004383)4.26823643
17Osteomalacia (HP:0002749)4.12835910
18Abnormality of the anterior horn cell (HP:0006802)4.11754104
19Degeneration of anterior horn cells (HP:0002398)4.11754104
20Focal seizures (HP:0007359)3.91020334
21Male pseudohermaphroditism (HP:0000037)3.77525294
22Focal motor seizures (HP:0011153)3.61490569
23Visual hallucinations (HP:0002367)3.52350854
24Tongue fasciculations (HP:0001308)3.49291896
25Distal upper limb amyotrophy (HP:0007149)3.48012269
26Upper limb amyotrophy (HP:0009129)3.48012269
27Hypoplastic heart (HP:0001961)3.39015506
28Male infertility (HP:0003251)3.36103370
29Epileptic encephalopathy (HP:0200134)3.19028008
30Action tremor (HP:0002345)3.12423519
31Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.10458987
32Short 4th metacarpal (HP:0010044)3.10458987
33Papilledema (HP:0001085)3.05598589
34True hermaphroditism (HP:0010459)2.97539397
35Atrophy/Degeneration involving motor neurons (HP:0007373)2.97060885
36Torticollis (HP:0000473)2.96852884
37Muscle fibrillation (HP:0010546)2.96085467
38Shallow orbits (HP:0000586)2.92568213
39Spinal muscular atrophy (HP:0007269)2.89301772
40Myopathic facies (HP:0002058)2.80563394
41Progressive cerebellar ataxia (HP:0002073)2.74728147
42Facial diplegia (HP:0001349)2.70276859
43Gonadotropin excess (HP:0000837)2.68371095
44Supranuclear gaze palsy (HP:0000605)2.65020684
45Neonatal short-limb short stature (HP:0008921)2.60613759
46Mutism (HP:0002300)2.59419588
47Ankle clonus (HP:0011448)2.59418139
48Obstructive sleep apnea (HP:0002870)2.57067878
49Insidious onset (HP:0003587)2.56389908
50Termporal pattern (HP:0011008)2.56389908
51Periauricular skin pits (HP:0100277)2.49883891
52Preauricular pit (HP:0004467)2.49883891
53Abnormality of the vocal cords (HP:0008777)2.48327917
54Hypoventilation (HP:0002791)2.47828021
55Protrusio acetabuli (HP:0003179)2.45993246
56Aqueductal stenosis (HP:0002410)2.45539142
57Pheochromocytoma (HP:0002666)2.42862129
58Insomnia (HP:0100785)2.40949832
59Renal duplication (HP:0000075)2.38711997
60Craniofacial dystonia (HP:0012179)2.38573586
61Short tibia (HP:0005736)2.37709036
62Focal dystonia (HP:0004373)2.36555884
63Sex reversal (HP:0012245)2.35100917
64Abnormal sex determination (HP:0012244)2.35100917
65Bowel diverticulosis (HP:0005222)2.34515343
66Turricephaly (HP:0000262)2.34397191
67Depression (HP:0000716)2.31688317
68Urinary bladder sphincter dysfunction (HP:0002839)2.30552297
69Clumsiness (HP:0002312)2.28317415
70Hypoplastic pelvis (HP:0008839)2.27895887
71Microglossia (HP:0000171)2.27510693
72Genetic anticipation (HP:0003743)2.25144412
73Abnormality of the 4th metacarpal (HP:0010012)2.22951996
74Hyperacusis (HP:0010780)2.22402698
75Focal segmental glomerulosclerosis (HP:0000097)2.19750423
76Absence seizures (HP:0002121)2.19386169
77Urinary urgency (HP:0000012)2.17241064
78Megalencephaly (HP:0001355)2.16714685
79Ankyloglossia (HP:0010296)2.16648327
80Weak cry (HP:0001612)2.15613791
81Aplasia/Hypoplasia of the tibia (HP:0005772)2.14877335
82Generalized tonic-clonic seizures (HP:0002069)2.13726152
83Sacral dimple (HP:0000960)2.13342670
84Macroorchidism (HP:0000053)2.12939706
85Broad metatarsal (HP:0001783)2.12780906
86Increased variability in muscle fiber diameter (HP:0003557)2.12671998
87Abnormal eating behavior (HP:0100738)2.12508145
88Fibular aplasia (HP:0002990)2.12357765
89Hypoplastic iliac wings (HP:0002866)2.11009438
90Complete atrioventricular canal defect (HP:0001674)2.09597625
91Pointed chin (HP:0000307)2.09349852
92Agitation (HP:0000713)2.08991354
93Anxiety (HP:0000739)2.08808433
94Ankle contracture (HP:0006466)2.07997873
95Atonic seizures (HP:0010819)2.07700602
96Atrioventricular canal defect (HP:0006695)2.07137366
97Polyphagia (HP:0002591)2.06259193
98Abnormality of the corticospinal tract (HP:0002492)2.05169411
99Broad-based gait (HP:0002136)2.04107022
100Neuroendocrine neoplasm (HP:0100634)2.04004061
101Neoplasm of the peripheral nervous system (HP:0100007)2.03588960
102Amyotrophic lateral sclerosis (HP:0007354)2.00044777
103Overgrowth (HP:0001548)1.99981635
104Relative macrocephaly (HP:0004482)1.98401875
105Poor eye contact (HP:0000817)1.97960498
106Excessive salivation (HP:0003781)1.97231076
107Drooling (HP:0002307)1.97231076
108Bladder diverticulum (HP:0000015)1.96459956
109Cutaneous finger syndactyly (HP:0010554)1.95677237
110Abnormal social behavior (HP:0012433)1.95259187
111Impaired social interactions (HP:0000735)1.95259187
112Limb dystonia (HP:0002451)1.95059379
113Germ cell neoplasia (HP:0100728)1.93368407
114Dialeptic seizures (HP:0011146)1.93167277
115Abnormality of the aortic arch (HP:0012303)1.92426382
116Postural instability (HP:0002172)1.91897385
117Infertility (HP:0000789)1.91745944
118Febrile seizures (HP:0002373)1.91302859
119Hepatoblastoma (HP:0002884)1.91068485
120Abnormality of pain sensation (HP:0010832)1.90680496
121Impaired pain sensation (HP:0007328)1.90680496
122Hypercortisolism (HP:0001578)1.89449048
123Lower limb amyotrophy (HP:0007210)1.88740693
124Dysdiadochokinesis (HP:0002075)1.88554187
125Elfin facies (HP:0004428)1.88290850
126Fetal akinesia sequence (HP:0001989)1.87298476
127Aplasia involving bones of the extremities (HP:0009825)1.86297979
128Aplasia involving bones of the upper limbs (HP:0009823)1.86297979
129Aplasia of the phalanges of the hand (HP:0009802)1.86297979
130Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.84178525
131Flat cornea (HP:0007720)1.84032348
132Renovascular hypertension (HP:0100817)1.82403213
133Enlarged penis (HP:0000040)1.82108558
134Abnormality of the lower motor neuron (HP:0002366)1.80869916
135Bulbar palsy (HP:0001283)1.80280074
136Bronchomalacia (HP:0002780)1.79890054
137Asymmetry of the thorax (HP:0001555)1.77599881
138Sleep apnea (HP:0010535)1.77292916
139Truncal ataxia (HP:0002078)1.76479049
140Female pseudohermaphroditism (HP:0010458)1.76372351
141Abnormal lung lobation (HP:0002101)1.76362580
142Impaired vibration sensation in the lower limbs (HP:0002166)1.75896827
143Overriding aorta (HP:0002623)1.73684377
144Cerebral aneurysm (HP:0004944)1.73075876
145Scanning speech (HP:0002168)1.72860192
146Buphthalmos (HP:0000557)1.72829735
147Myotonia (HP:0002486)1.72737868
148Abnormality of the fetal cardiovascular system (HP:0010948)1.72042478
149Abnormal umbilical cord blood vessels (HP:0011403)1.72042478
150Single umbilical artery (HP:0001195)1.72042478
151EEG with generalized epileptiform discharges (HP:0011198)1.71982082
152Spastic gait (HP:0002064)1.71277903
153Type 1 muscle fiber predominance (HP:0003803)1.71259699
154Labial hypoplasia (HP:0000066)1.71146320
155Hypsarrhythmia (HP:0002521)1.71114546
156Narrow nasal bridge (HP:0000446)1.70469686
157Stenosis of the external auditory canal (HP:0000402)1.69433045
158Abnormality of the motor neurons (HP:0002450)1.69282277
159Abnormal neuron morphology (HP:0012757)1.69282277
160Annular pancreas (HP:0001734)1.68338196
161Congenital diaphragmatic hernia (HP:0000776)1.68320828
162Epileptiform EEG discharges (HP:0011182)1.66695898
163Premature rupture of membranes (HP:0001788)1.66515874
164Abnormality of the musculature of the hand (HP:0001421)1.65927871
165Coronal craniosynostosis (HP:0004440)1.65868474
166Cortical dysplasia (HP:0002539)1.65761630
167Abnormality of the ischium (HP:0003174)1.65237996
168Mildly elevated creatine phosphokinase (HP:0008180)1.65170702
169Tachypnea (HP:0002789)1.65032039
170Vertebral arch anomaly (HP:0008438)1.64632474
171Bell-shaped thorax (HP:0001591)1.64482204
172Skin pits (HP:0100276)1.63102031
173Glomerulosclerosis (HP:0000096)1.61345201
174Arthropathy (HP:0003040)1.60297326
175Underdeveloped supraorbital ridges (HP:0009891)1.59430921
176Pulmonic stenosis (HP:0001642)1.58933964
177Tibial bowing (HP:0002982)1.56930626
178Hyperglycinemia (HP:0002154)1.55064528
179Hypoplastic female external genitalia (HP:0012815)1.53703348
180Abnormality of the thoracic spine (HP:0100711)1.49331860
181Abnormal pancreas size (HP:0012094)1.49172737
182Abnormality of the phalanges of the hallux (HP:0010057)1.48766363
183Aplasia/Hypoplasia of the fibula (HP:0006492)1.48650412
184Vitreoretinal degeneration (HP:0000655)1.48356752
185Lower limb muscle weakness (HP:0007340)1.47118293
186Mitral valve prolapse (HP:0001634)1.44950049
187Abnormality of the pupil (HP:0000615)1.44449839
188Hyperpituitarism (HP:0010514)1.44123856

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.31692200
2MAP3K94.27083219
3NTRK34.20645895
4AKT33.21632889
5TAOK23.02829727
6WNK33.02149348
7MINK12.69732576
8MAP3K62.68903868
9KSR22.36852463
10MAP3K42.35732436
11DYRK32.34400684
12PAK62.31411732
13LATS22.31256252
14DDR22.17217756
15EPHA42.07340135
16NTRK12.03154454
17GRK51.91719095
18MAP2K71.90189356
19PDK21.88128049
20NTRK21.87525781
21MAP2K41.84627917
22PHKG21.80214702
23PHKG11.80214702
24NEK91.62731030
25PINK11.58256346
26BCKDK1.58220848
27WNK41.57743390
28PRKD31.53103862
29CAMKK11.52837249
30LMTK21.52516299
31SIK21.50269392
32PLK21.46267478
33MYLK1.46250429
34DYRK1B1.43404002
35KSR11.43301714
36DAPK21.41991061
37SIK11.40935584
38CDK51.37276425
39MAP3K21.30579924
40MAP3K121.27132589
41PDGFRA1.23920156
42RET1.23855476
43MAPK131.20942720
44ADRBK21.20267641
45PRKCH1.19550502
46NEK11.19270348
47BCR1.17697418
48PAK31.16497595
49ACVR1B1.14981194
50CASK1.12451924
51SGK31.11049522
52ERBB31.08539306
53PRKCG1.07658996
54FLT31.07278219
55CAMK41.05979148
56ICK1.05746143
57SGK4941.04178444
58SGK2231.04178444
59SGK21.03594379
60RPS6KC11.00171630
61RPS6KL11.00171630
62TRIB30.99415817
63CDK140.98529697
64RPS6KA60.98038222
65EPHA30.96335474
66STK380.94828919
67MET0.94076636
68CDK190.93805368
69PRPF4B0.91588334
70UHMK10.89468011
71CDK180.88208471
72CDK150.86290260
73CSNK1G10.85789332
74MAP3K50.85619755
75ALK0.84896515
76CCNB10.83527834
77LIMK10.80377405
78WNK10.79111579
79SCYL20.78853099
80CAMKK20.76271499
81MARK20.76029281
82FER0.75421277
83TAOK10.74069218
84CAMK1G0.73590039
85PRKACG0.73448883
86NEK20.73400448
87CSNK1G20.72585636
88ERBB40.71847567
89MAP2K10.71707247
90DYRK20.71481031
91CDK11A0.71474175
92RPS6KA50.70700004
93CSNK1G30.69505408
94CAMK2A0.68374161
95PRKAA10.68213045
96FGFR20.68162759
97FGFR10.67664820
98CAMK10.65270531
99PTK2B0.63514204
100CDC42BPA0.63251058
101PRKCZ0.62793307
102PKN20.62397602
103MAP3K130.60930043
104SGK10.59900687
105DAPK10.59755872
106RPS6KA20.59379662
107ADRBK10.55721856
108ROCK10.55623431
109GRK10.55586603
110PRKACA0.54205800
111PRKCE0.53914914
112LATS10.53543332
113MAP3K10.53331035
114TYRO30.53137100
115FES0.51858044
116RIPK10.49661115
117RPS6KA30.48847611
118RIPK40.48648966
119EPHB20.48641419
120MELK0.48210353
121MAPK100.48156905
122STK110.46695778
123ROCK20.45881155
124MAPK80.45866941
125BRAF0.45439672
126PAK20.45262340
127PDK10.44874137
128ILK0.44848317
129ARAF0.43068191
130PTK20.42608615
131BMX0.41431226
132DYRK1A0.41372039
133PDPK10.40309063
134TNIK0.39571725
135FYN0.39347102
136PDGFRB0.39294896
137MAP3K70.39082860
138AURKA0.39043995
139PIK3CA0.38995247
140PRKD20.38418012
141MAP2K60.37818619
142CSNK1D0.37559490
143CSNK1A1L0.37142914
144MAPK90.37125798
145PRKG10.34322093
146RPS6KA10.31051126
147MAPK30.30468753

Predicted pathways (KEGG)

RankGene SetZ-score
1Steroid biosynthesis_Homo sapiens_hsa001003.78462884
2Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.62105292
3Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010403.34872271
4Synaptic vesicle cycle_Homo sapiens_hsa047212.81587990
5Propanoate metabolism_Homo sapiens_hsa006402.53842966
6Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.49213573
7Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.37223459
8Nicotine addiction_Homo sapiens_hsa050332.36971683
9GABAergic synapse_Homo sapiens_hsa047272.36088399
10Olfactory transduction_Homo sapiens_hsa047402.31395195
11Circadian entrainment_Homo sapiens_hsa047132.30438720
12Long-term potentiation_Homo sapiens_hsa047202.20430443
13Vitamin digestion and absorption_Homo sapiens_hsa049772.18890761
14Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.18008466
15Fatty acid elongation_Homo sapiens_hsa000622.15176860
16Glutamatergic synapse_Homo sapiens_hsa047242.04403530
17Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.03967323
18Morphine addiction_Homo sapiens_hsa050322.00023221
19Dopaminergic synapse_Homo sapiens_hsa047281.98824744
20Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.98470309
21Amphetamine addiction_Homo sapiens_hsa050311.90229007
22Cholinergic synapse_Homo sapiens_hsa047251.90024310
23Salivary secretion_Homo sapiens_hsa049701.81579443
24Insulin secretion_Homo sapiens_hsa049111.78331585
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.77277730
26Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.71125566
27Aldosterone synthesis and secretion_Homo sapiens_hsa049251.69052678
28Pyruvate metabolism_Homo sapiens_hsa006201.64723090
29Renin secretion_Homo sapiens_hsa049241.62122927
30Gastric acid secretion_Homo sapiens_hsa049711.59020381
31Ovarian steroidogenesis_Homo sapiens_hsa049131.57439594
32Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.55191733
33Long-term depression_Homo sapiens_hsa047301.53150695
34Cocaine addiction_Homo sapiens_hsa050301.48823555
35Axon guidance_Homo sapiens_hsa043601.47885372
36Gap junction_Homo sapiens_hsa045401.47567065
37Steroid hormone biosynthesis_Homo sapiens_hsa001401.47537873
38GnRH signaling pathway_Homo sapiens_hsa049121.45132686
39Oxytocin signaling pathway_Homo sapiens_hsa049211.43810760
40Glioma_Homo sapiens_hsa052141.41504938
41Type II diabetes mellitus_Homo sapiens_hsa049301.41341069
42Serotonergic synapse_Homo sapiens_hsa047261.41288881
43Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.37536765
44Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.36797407
45Taste transduction_Homo sapiens_hsa047421.33238138
46Estrogen signaling pathway_Homo sapiens_hsa049151.29568807
47Nitrogen metabolism_Homo sapiens_hsa009101.28826233
48Melanogenesis_Homo sapiens_hsa049161.28637176
49TGF-beta signaling pathway_Homo sapiens_hsa043501.17875700
50Dorso-ventral axis formation_Homo sapiens_hsa043201.16932770
51Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.16272507
52Calcium signaling pathway_Homo sapiens_hsa040201.15983517
53Butanoate metabolism_Homo sapiens_hsa006501.15446752
54ErbB signaling pathway_Homo sapiens_hsa040121.14393589
55cAMP signaling pathway_Homo sapiens_hsa040241.14303900
56Maturity onset diabetes of the young_Homo sapiens_hsa049501.12615698
57Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.11987443
58Neurotrophin signaling pathway_Homo sapiens_hsa047221.08938539
59Oocyte meiosis_Homo sapiens_hsa041141.07242101
60Fatty acid metabolism_Homo sapiens_hsa012121.06382793
61Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.06243118
62cGMP-PKG signaling pathway_Homo sapiens_hsa040221.05211907
63Dilated cardiomyopathy_Homo sapiens_hsa054141.04968290
64Endometrial cancer_Homo sapiens_hsa052131.03270116
65Thyroid hormone synthesis_Homo sapiens_hsa049180.89493777
66Hedgehog signaling pathway_Homo sapiens_hsa043400.89473486
67Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.89255177
68mTOR signaling pathway_Homo sapiens_hsa041500.87806170
69Phospholipase D signaling pathway_Homo sapiens_hsa040720.85753828
70Thyroid hormone signaling pathway_Homo sapiens_hsa049190.83811557
71Vascular smooth muscle contraction_Homo sapiens_hsa042700.80736098
72Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.79020277
73Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.78244328
74Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.77985382
75MAPK signaling pathway_Homo sapiens_hsa040100.77111701
76Insulin signaling pathway_Homo sapiens_hsa049100.76877132
77Vibrio cholerae infection_Homo sapiens_hsa051100.75980442
78Collecting duct acid secretion_Homo sapiens_hsa049660.75670659
79Colorectal cancer_Homo sapiens_hsa052100.75270645
80Alcoholism_Homo sapiens_hsa050340.74662372
81Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.74545688
82Choline metabolism in cancer_Homo sapiens_hsa052310.74194655
83Renal cell carcinoma_Homo sapiens_hsa052110.73502372
84Wnt signaling pathway_Homo sapiens_hsa043100.72955517
85Phosphatidylinositol signaling system_Homo sapiens_hsa040700.70982765
86VEGF signaling pathway_Homo sapiens_hsa043700.70953129
87Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.69899925
88Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.69598177
89Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.68570820
90Ras signaling pathway_Homo sapiens_hsa040140.68191727
91Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.67753382
92Longevity regulating pathway - mammal_Homo sapiens_hsa042110.65394954
93Rap1 signaling pathway_Homo sapiens_hsa040150.65154710
94Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.65101913
95Central carbon metabolism in cancer_Homo sapiens_hsa052300.64789910
96Galactose metabolism_Homo sapiens_hsa000520.64705227
97Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.64693339
98Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.64670550
99Basal cell carcinoma_Homo sapiens_hsa052170.64433277
100Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.64235976
101Primary bile acid biosynthesis_Homo sapiens_hsa001200.62908832
102Focal adhesion_Homo sapiens_hsa045100.62581791
103Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.62518436
104Non-small cell lung cancer_Homo sapiens_hsa052230.62186947
105Glucagon signaling pathway_Homo sapiens_hsa049220.62052159
106Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.61289134
107Proteoglycans in cancer_Homo sapiens_hsa052050.60976621
108Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.60756207
109Bile secretion_Homo sapiens_hsa049760.60631322
110Melanoma_Homo sapiens_hsa052180.59415375
111Protein digestion and absorption_Homo sapiens_hsa049740.58865096
112Fat digestion and absorption_Homo sapiens_hsa049750.58508594
113Hippo signaling pathway_Homo sapiens_hsa043900.58456641
114Endocytosis_Homo sapiens_hsa041440.57779042
115Cardiac muscle contraction_Homo sapiens_hsa042600.57742902
116Thyroid cancer_Homo sapiens_hsa052160.57682894
117Carbohydrate digestion and absorption_Homo sapiens_hsa049730.57166359
118Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.57160379
119beta-Alanine metabolism_Homo sapiens_hsa004100.57117540
120Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.57010644
121Sphingolipid signaling pathway_Homo sapiens_hsa040710.54029706
122Fatty acid biosynthesis_Homo sapiens_hsa000610.53635555
123ECM-receptor interaction_Homo sapiens_hsa045120.53096175
124Arginine biosynthesis_Homo sapiens_hsa002200.51293602
125Pancreatic secretion_Homo sapiens_hsa049720.50617568
126Amoebiasis_Homo sapiens_hsa051460.49977487
127Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49935589
128Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.48545620
129Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.48538954
130Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.48230704
131Prion diseases_Homo sapiens_hsa050200.47655003
132Carbon metabolism_Homo sapiens_hsa012000.46821476
133Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.46176185
134Tight junction_Homo sapiens_hsa045300.45952481
135Chemical carcinogenesis_Homo sapiens_hsa052040.45595518
136Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.45194449
137Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.44546386
138Vitamin B6 metabolism_Homo sapiens_hsa007500.43688590
139Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.43668575
140Arginine and proline metabolism_Homo sapiens_hsa003300.42943883
141Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.42403700
142Complement and coagulation cascades_Homo sapiens_hsa046100.42127637
143PI3K-Akt signaling pathway_Homo sapiens_hsa041510.41700898
144PPAR signaling pathway_Homo sapiens_hsa033200.39333062
145Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.39045289

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