RCL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)5.58944993
2L-phenylalanine catabolic process (GO:0006559)5.58944993
3L-phenylalanine metabolic process (GO:0006558)5.57326427
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)5.57326427
5glycine metabolic process (GO:0006544)5.28761210
6aromatic amino acid family catabolic process (GO:0009074)5.08797961
7triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.84162518
8serine family amino acid biosynthetic process (GO:0009070)4.72827427
9serine family amino acid catabolic process (GO:0009071)4.72271489
10kynurenine metabolic process (GO:0070189)4.67627306
11tryptophan catabolic process (GO:0006569)4.65583825
12indole-containing compound catabolic process (GO:0042436)4.65583825
13indolalkylamine catabolic process (GO:0046218)4.65583825
14cysteine metabolic process (GO:0006534)4.65336025
15glyoxylate metabolic process (GO:0046487)4.62564404
16bile acid biosynthetic process (GO:0006699)4.50785919
17negative regulation of fibrinolysis (GO:0051918)4.50243245
18protoporphyrinogen IX metabolic process (GO:0046501)4.49720362
19serine family amino acid metabolic process (GO:0009069)4.47197903
20urea cycle (GO:0000050)4.40069520
21urea metabolic process (GO:0019627)4.40069520
22tryptophan metabolic process (GO:0006568)4.37859605
23protoporphyrinogen IX biosynthetic process (GO:0006782)4.35227595
24sulfur amino acid catabolic process (GO:0000098)4.31425953
25regulation of protein activation cascade (GO:2000257)4.22312892
26alpha-linolenic acid metabolic process (GO:0036109)4.20108235
27L-serine metabolic process (GO:0006563)4.17189280
28regulation of fibrinolysis (GO:0051917)4.16782236
29high-density lipoprotein particle remodeling (GO:0034375)4.13349439
30folic acid metabolic process (GO:0046655)4.10894957
31nitrogen cycle metabolic process (GO:0071941)4.06019948
32peptidyl-glutamic acid carboxylation (GO:0017187)3.99956886
33protein carboxylation (GO:0018214)3.99956886
34complement activation, alternative pathway (GO:0006957)3.95210214
35regulation of complement activation (GO:0030449)3.94233451
36imidazole-containing compound metabolic process (GO:0052803)3.92657967
37rRNA modification (GO:0000154)3.91166464
38folic acid-containing compound biosynthetic process (GO:0009396)3.86683137
39lysine metabolic process (GO:0006553)3.85809759
40lysine catabolic process (GO:0006554)3.85809759
41aromatic amino acid family metabolic process (GO:0009072)3.85407126
42amino-acid betaine metabolic process (GO:0006577)3.85056708
43pseudouridine synthesis (GO:0001522)3.83422128
44mitochondrial RNA metabolic process (GO:0000959)3.81070440
45bile acid metabolic process (GO:0008206)3.80186188
46porphyrin-containing compound biosynthetic process (GO:0006779)3.80011599
47homocysteine metabolic process (GO:0050667)3.78916790
48negative regulation of cholesterol transport (GO:0032375)3.73339170
49negative regulation of sterol transport (GO:0032372)3.73339170
50alpha-amino acid catabolic process (GO:1901606)3.71279276
51DNA strand elongation involved in DNA replication (GO:0006271)3.69425436
52one-carbon metabolic process (GO:0006730)3.68460607
53proteasome assembly (GO:0043248)3.67250118
54rRNA methylation (GO:0031167)3.61007205
55fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.60753109
56regulation of cholesterol esterification (GO:0010872)3.59936407
57maturation of 5.8S rRNA (GO:0000460)3.55590221
58protein-lipid complex remodeling (GO:0034368)3.55185631
59macromolecular complex remodeling (GO:0034367)3.55185631
60plasma lipoprotein particle remodeling (GO:0034369)3.55185631
61regulation of triglyceride catabolic process (GO:0010896)3.54829002
62porphyrin-containing compound metabolic process (GO:0006778)3.54036600
63tetrapyrrole biosynthetic process (GO:0033014)3.53909928
64heme biosynthetic process (GO:0006783)3.52446262
65tetrahydrofolate metabolic process (GO:0046653)3.51153566
66DNA strand elongation (GO:0022616)3.50102040
67reverse cholesterol transport (GO:0043691)3.49764402
68acylglycerol homeostasis (GO:0055090)3.47689151
69triglyceride homeostasis (GO:0070328)3.47689151
70telomere maintenance via semi-conservative replication (GO:0032201)3.44522235
71blood coagulation, intrinsic pathway (GO:0007597)3.41501728
72purine nucleobase biosynthetic process (GO:0009113)3.40954309
73nucleobase biosynthetic process (GO:0046112)3.40382245
74cellular amino acid catabolic process (GO:0009063)3.40047790
75heme metabolic process (GO:0042168)3.38158684
76ethanol oxidation (GO:0006069)3.37472386
77tyrosine metabolic process (GO:0006570)3.33661439
78bile acid and bile salt transport (GO:0015721)3.33616318
79IMP biosynthetic process (GO:0006188)3.31253977
80plasma lipoprotein particle clearance (GO:0034381)3.29007933
81folic acid-containing compound metabolic process (GO:0006760)3.27985212
82aldehyde catabolic process (GO:0046185)3.26218854
83phospholipid efflux (GO:0033700)3.24193001
84ribosome assembly (GO:0042255)3.24155333
85DNA replication initiation (GO:0006270)3.24041027
86amino acid salvage (GO:0043102)3.22642154
87L-methionine salvage (GO:0071267)3.22642154
88L-methionine biosynthetic process (GO:0071265)3.22642154
89methionine biosynthetic process (GO:0009086)3.20274448
90L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.18984395
91cellular biogenic amine catabolic process (GO:0042402)3.18296596
92amine catabolic process (GO:0009310)3.18296596
93indolalkylamine metabolic process (GO:0006586)3.17853829
94coenzyme catabolic process (GO:0009109)3.14907964
95chromatin remodeling at centromere (GO:0031055)3.13683314
96pteridine-containing compound biosynthetic process (GO:0042559)3.13092639
97heme transport (GO:0015886)3.12240670
98sulfur amino acid biosynthetic process (GO:0000097)3.11858860
99CENP-A containing nucleosome assembly (GO:0034080)3.10318356
100* ribosome biogenesis (GO:0042254)3.10238299
101DNA replication checkpoint (GO:0000076)3.09765322
102transcription from mitochondrial promoter (GO:0006390)3.06382383
103arginine metabolic process (GO:0006525)3.05659104
104somatic hypermutation of immunoglobulin genes (GO:0016446)3.03984256
105somatic diversification of immune receptors via somatic mutation (GO:0002566)3.03984256
106cellular modified amino acid catabolic process (GO:0042219)3.02812658
107sulfur amino acid metabolic process (GO:0000096)3.02698837
108glutamate metabolic process (GO:0006536)3.01941601
109benzene-containing compound metabolic process (GO:0042537)3.01894098
110DNA double-strand break processing (GO:0000729)3.01374889
111positive regulation of triglyceride lipase activity (GO:0061365)3.01042745
112positive regulation of lipoprotein lipase activity (GO:0051006)3.01042745
113plasma lipoprotein particle assembly (GO:0034377)2.99552887
114telomere maintenance via recombination (GO:0000722)2.98708362
115methionine metabolic process (GO:0006555)2.98128430
116nicotinamide nucleotide biosynthetic process (GO:0019359)2.96897540
117pyridine nucleotide biosynthetic process (GO:0019363)2.96897540
118pteridine-containing compound metabolic process (GO:0042558)2.96793879
119response to nitrosative stress (GO:0051409)2.96571489
120complement activation, classical pathway (GO:0006958)2.96287110
121cofactor catabolic process (GO:0051187)2.95910743
122viral mRNA export from host cell nucleus (GO:0046784)2.95818117
123IMP metabolic process (GO:0046040)2.95653207
124negative regulation of fatty acid biosynthetic process (GO:0045717)2.95128752
1252-oxoglutarate metabolic process (GO:0006103)2.95088512
126respiratory chain complex IV assembly (GO:0008535)2.94648430
127NAD biosynthetic process (GO:0009435)2.93015580
128urate metabolic process (GO:0046415)2.92966054
129S-adenosylmethionine metabolic process (GO:0046500)2.92798713
130DNA deamination (GO:0045006)2.92591948
131fibrinolysis (GO:0042730)2.92368738
132rRNA processing (GO:0006364)2.92091341
133cellular glucuronidation (GO:0052695)2.92065501
134organic acid catabolic process (GO:0016054)2.91326185
135carboxylic acid catabolic process (GO:0046395)2.91326185
136peptidyl-histidine modification (GO:0018202)2.90306932
137aspartate family amino acid biosynthetic process (GO:0009067)2.89294578
138cellular ketone body metabolic process (GO:0046950)2.88479327
139low-density lipoprotein particle remodeling (GO:0034374)2.88299302
140valine metabolic process (GO:0006573)2.87185671
141DNA catabolic process, exonucleolytic (GO:0000738)2.86973841
142cholesterol efflux (GO:0033344)2.86809992
143mitotic recombination (GO:0006312)2.85538623
144rRNA metabolic process (GO:0016072)2.85309723
145replication fork processing (GO:0031297)2.79765111
146tRNA modification (GO:0006400)2.76773379
147histone exchange (GO:0043486)2.74782379
148tRNA processing (GO:0008033)2.74505844
149amino acid activation (GO:0043038)2.74302248
150tRNA aminoacylation (GO:0043039)2.74302248
151tRNA metabolic process (GO:0006399)2.74057623
152tRNA aminoacylation for protein translation (GO:0006418)2.72986624
153DNA replication-dependent nucleosome assembly (GO:0006335)2.72596494
154DNA replication-dependent nucleosome organization (GO:0034723)2.72596494
155pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.70814465
156telomere maintenance via telomere lengthening (GO:0010833)2.69750236
157* ribonucleoprotein complex biogenesis (GO:0022613)2.68470808
158exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.68168068
159ncRNA processing (GO:0034470)2.67933464
160ncRNA metabolic process (GO:0034660)2.65451859
161tRNA methylation (GO:0030488)2.65403701
162maturation of SSU-rRNA (GO:0030490)2.65222342
163DNA ligation (GO:0006266)2.64717174
164nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.64349890
165ribosomal small subunit assembly (GO:0000028)2.64296389
166nucleotide-excision repair, DNA gap filling (GO:0006297)2.62127659
167mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.62036442
168mitochondrial respiratory chain complex I assembly (GO:0032981)2.62036442
169NADH dehydrogenase complex assembly (GO:0010257)2.62036442
170mitochondrial respiratory chain complex assembly (GO:0033108)2.59859474
171protein-cofactor linkage (GO:0018065)2.58234521
172RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.56494311
173meiotic chromosome segregation (GO:0045132)2.56066610
174non-recombinational repair (GO:0000726)2.55316115
175double-strand break repair via nonhomologous end joining (GO:0006303)2.55316115
176double-strand break repair via homologous recombination (GO:0000724)2.55017103
177RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.53425435
178tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.53425435
179recombinational repair (GO:0000725)2.52263673
180ubiquinone biosynthetic process (GO:0006744)2.50821782
181maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.49530731
182regulation of mitotic spindle checkpoint (GO:1903504)2.49444415
183regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.49444415
184pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.49206689
185ribosomal large subunit biogenesis (GO:0042273)2.48971203
186regulation of histone H3-K9 methylation (GO:0051570)2.48525598
187regulation of mitochondrial translation (GO:0070129)2.48177245

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse6.50318846
2E2F7_22180533_ChIP-Seq_HELA_Human5.00547155
3* RXR_22158963_ChIP-Seq_LIVER_Mouse4.30015850
4* PPARA_22158963_ChIP-Seq_LIVER_Mouse3.89224424
5EGR1_23403033_ChIP-Seq_LIVER_Mouse3.73923041
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse3.43905788
7* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.39586223
8* MYC_18555785_ChIP-Seq_MESCs_Mouse3.33283864
9* PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.95702814
10* LXR_22158963_ChIP-Seq_LIVER_Mouse2.95614515
11CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.91935007
12FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.83523828
13FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.40462495
14KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.36850942
15* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.35352706
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.32306155
17MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.22216519
18* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.12300608
19ETS1_20019798_ChIP-Seq_JURKAT_Human2.11106184
20GABP_17652178_ChIP-ChIP_JURKAT_Human2.10138591
21EST1_17652178_ChIP-ChIP_JURKAT_Human2.09717829
22MYC_19079543_ChIP-ChIP_MESCs_Mouse2.09101945
23CREB1_15753290_ChIP-ChIP_HEK293T_Human2.08838672
24E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.91915365
25E2F4_17652178_ChIP-ChIP_JURKAT_Human1.90927982
26FOXM1_23109430_ChIP-Seq_U2OS_Human1.87542007
27YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.86845439
28FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.84581955
29NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.78420712
30ELF1_17652178_ChIP-ChIP_JURKAT_Human1.75737016
31AR_21909140_ChIP-Seq_LNCAP_Human1.75372361
32XRN2_22483619_ChIP-Seq_HELA_Human1.75103133
33* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.73531140
34* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.72078881
35HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.62604407
36VDR_23849224_ChIP-Seq_CD4+_Human1.57494135
37ZNF274_21170338_ChIP-Seq_K562_Hela1.56838920
38DCP1A_22483619_ChIP-Seq_HELA_Human1.55486618
39STAT3_1855785_ChIP-Seq_MESCs_Mouse1.55140110
40GABP_19822575_ChIP-Seq_HepG2_Human1.52988700
41NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.51593338
42* MYC_18940864_ChIP-ChIP_HL60_Human1.50382144
43FOXP3_21729870_ChIP-Seq_TREG_Human1.50373240
44HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.47629841
45KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.46255207
46IRF1_19129219_ChIP-ChIP_H3396_Human1.45886606
47* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.45308152
48* TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.44564495
49CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.38334752
50MYCN_18555785_ChIP-Seq_MESCs_Mouse1.38306920
51* GATA1_22025678_ChIP-Seq_K562_Human1.33787623
52ZFX_18555785_ChIP-Seq_MESCs_Mouse1.33354194
53POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.31724440
54MYC_22102868_ChIP-Seq_BL_Human1.31329780
55TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.30030154
56* SRF_21415370_ChIP-Seq_HL-1_Mouse1.29277192
57PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.29018942
58VDR_22108803_ChIP-Seq_LS180_Human1.28606793
59SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.27577575
60POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.25411076
61KDM5A_27292631_Chip-Seq_BREAST_Human1.23775865
62NANOG_18555785_ChIP-Seq_MESCs_Mouse1.22343083
63E2F1_21310950_ChIP-Seq_MCF-7_Human1.19465831
64CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.17565755
65* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.17537938
66NOTCH1_21737748_ChIP-Seq_TLL_Human1.14192845
67FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.13844328
68ESR1_15608294_ChIP-ChIP_MCF-7_Human1.12932565
69PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.11172714
70THAP11_20581084_ChIP-Seq_MESCs_Mouse1.09357474
71FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.08360534
72MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.07889865
73ERG_20887958_ChIP-Seq_HPC-7_Mouse1.07889802
74EWS_26573619_Chip-Seq_HEK293_Human1.07056841
75HOXB4_20404135_ChIP-ChIP_EML_Mouse1.07009217
76YY1_21170310_ChIP-Seq_MESCs_Mouse1.06813453
77TTF2_22483619_ChIP-Seq_HELA_Human1.05076781
78EGR1_19374776_ChIP-ChIP_THP-1_Human1.04076246
79MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.02828606
80ZNF263_19887448_ChIP-Seq_K562_Human1.02389612
81KLF4_18555785_ChIP-Seq_MESCs_Mouse1.02137711
82* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.01026393
83TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.00657320
84ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.98273529
85TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.96325774
86NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.94855278
87CLOCK_20551151_ChIP-Seq_293T_Human0.94315136
88CIITA_25753668_ChIP-Seq_RAJI_Human0.93965535
89BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.93942915
90ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.92032673
91RXRA_24833708_ChIP-Seq_LIVER_Mouse0.88790382
92SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.88112118
93* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.87716535
94ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.87142901
95STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.86214390
96IGF1R_20145208_ChIP-Seq_DFB_Human0.85802470
97DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.85742789
98CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.85031876
99PADI4_21655091_ChIP-ChIP_MCF-7_Human0.84203357
100GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.83498815
101NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.83322341
102E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.83164900
103TFEB_21752829_ChIP-Seq_HELA_Human0.82831485
104CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.82823685
105SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.81980277
106GATA1_22383799_ChIP-Seq_G1ME_Mouse0.80423738
107PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.79754807
108CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.79154998
109OCT4_18692474_ChIP-Seq_MEFs_Mouse0.79135846
110HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.78970439
111RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.77892866
112FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.77699277
113SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.76814966
114VDR_21846776_ChIP-Seq_THP-1_Human0.76381846
115ELK1_19687146_ChIP-ChIP_HELA_Human0.75913920
116STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.75809357
117HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.74629770
118POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.74170918
119* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.74089505
120EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.72855607
121TP53_22573176_ChIP-Seq_HFKS_Human0.72739918
122RBPJ_22232070_ChIP-Seq_NCS_Mouse0.72635768
123TBX5_21415370_ChIP-Seq_HL-1_Mouse0.70656102
124SCL_19346495_ChIP-Seq_HPC-7_Human0.69773818
125SALL1_21062744_ChIP-ChIP_HESCs_Human0.69214409
126GATA1_19941826_ChIP-Seq_K562_Human0.68581239
127SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.64354806
128CHD1_26751641_Chip-Seq_LNCaP_Human0.61908570
129PHF8_20622853_ChIP-Seq_HELA_Human0.60040759
130FUS_26573619_Chip-Seq_HEK293_Human0.59405669

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system6.83248388
2MP0005360_urolithiasis6.01884515
3MP0005085_abnormal_gallbladder_physiolo5.22207342
4MP0005365_abnormal_bile_salt5.10437541
5MP0003806_abnormal_nucleotide_metabolis4.78916471
6MP0008875_abnormal_xenobiotic_pharmacok3.96932040
7MP0009840_abnormal_foam_cell3.48220361
8MP0003252_abnormal_bile_duct2.93253558
9MP0010329_abnormal_lipoprotein_level2.86608232
10MP0005083_abnormal_biliary_tract2.57913835
11MP0005332_abnormal_amino_acid2.31776564
12MP0003693_abnormal_embryo_hatching2.26516923
13MP0001666_abnormal_nutrient_absorption2.08249000
14MP0000609_abnormal_liver_physiology2.07727990
15MP0003191_abnormal_cellular_cholesterol2.02794522
16MP0003646_muscle_fatigue1.94463612
17MP0003195_calcinosis1.93674529
18MP0003186_abnormal_redox_activity1.84812724
19MP0008995_early_reproductive_senescence1.82009029
20MP0003656_abnormal_erythrocyte_physiolo1.81737356
21MP0001764_abnormal_homeostasis1.80625815
22MP0005319_abnormal_enzyme/_coenzyme1.79810173
23MP0008877_abnormal_DNA_methylation1.70996166
24MP0004957_abnormal_blastocyst_morpholog1.64609936
25MP0004019_abnormal_vitamin_homeostasis1.63891654
26MP0002138_abnormal_hepatobiliary_system1.57490593
27MP0003111_abnormal_nucleus_morphology1.56469722
28MP0002118_abnormal_lipid_homeostasis1.56411553
29MP0003868_abnormal_feces_composition1.47159637
30MP0010094_abnormal_chromosome_stability1.42164725
31MP0000598_abnormal_liver_morphology1.41655084
32MP0009697_abnormal_copulation1.39399761
33MP0003718_maternal_effect1.36665872
34MP0003077_abnormal_cell_cycle1.33650102
35MP0005584_abnormal_enzyme/coenzyme_acti1.30422201
36MP0001929_abnormal_gametogenesis1.29376976
37MP0005451_abnormal_body_composition1.23911909
38MP0006036_abnormal_mitochondrial_physio1.20130068
39MP0008057_abnormal_DNA_replication1.18680475
40MP0004145_abnormal_muscle_electrophysio1.18238401
41MP0000372_irregular_coat_pigmentation1.18133574
42MP0002396_abnormal_hematopoietic_system1.15426333
43MP0009643_abnormal_urine_homeostasis1.13370685
44MP0003705_abnormal_hypodermis_morpholog1.10545495
45MP0003763_abnormal_thymus_physiology1.10417859
46MP0002102_abnormal_ear_morphology1.09582459
47MP0008872_abnormal_physiological_respon1.08867715
48MP0003011_delayed_dark_adaptation1.08184217
49MP0002160_abnormal_reproductive_system1.06556531
50MP0002876_abnormal_thyroid_physiology1.06236338
51MP0009763_increased_sensitivity_to1.04441689
52MP0002210_abnormal_sex_determination1.04247225
53MP0008469_abnormal_protein_level1.03230595
54MP0001853_heart_inflammation1.01853919
55MP0008058_abnormal_DNA_repair1.01379872
56MP0005397_hematopoietic_system_phenotyp0.98189348
57MP0001545_abnormal_hematopoietic_system0.98189348
58MP0001145_abnormal_male_reproductive0.96340033
59MP0003698_abnormal_male_reproductive0.96292607
60MP0002009_preneoplasia0.95884755
61MP0006035_abnormal_mitochondrial_morpho0.95438692
62MP0000653_abnormal_sex_gland0.95219521
63MP0005410_abnormal_fertilization0.93284846
64MP0005266_abnormal_metabolism0.90264502
65MP0000749_muscle_degeneration0.90048795
66MP0008775_abnormal_heart_ventricle0.89223605
67MP0001730_embryonic_growth_arrest0.89056836
68MP0003315_abnormal_perineum_morphology0.86777546
69MP0005636_abnormal_mineral_homeostasis0.86282612
70MP0005645_abnormal_hypothalamus_physiol0.85307094
71MP0005376_homeostasis/metabolism_phenot0.85299929
72MP0009764_decreased_sensitivity_to0.85117140
73MP0005220_abnormal_exocrine_pancreas0.84240272
74MP0006072_abnormal_retinal_apoptosis0.82692949
75MP0002163_abnormal_gland_morphology0.82418629
76MP0000703_abnormal_thymus_morphology0.81688299
77MP0003436_decreased_susceptibility_to0.80846513
78MP0005647_abnormal_sex_gland0.80817319
79MP0002132_abnormal_respiratory_system0.80147766
80MP0005464_abnormal_platelet_physiology0.79508552
81MP0002837_dystrophic_cardiac_calcinosis0.78871745
82MP0008007_abnormal_cellular_replicative0.78183296
83MP0001661_extended_life_span0.77852963
84MP0010352_gastrointestinal_tract_polyps0.77121277
85MP0009765_abnormal_xenobiotic_induced0.77002922
86MP0002269_muscular_atrophy0.76994661
87MP0005389_reproductive_system_phenotype0.76466928
88MP0008789_abnormal_olfactory_epithelium0.75511678
89MP0009642_abnormal_blood_homeostasis0.74375426
90MP0002019_abnormal_tumor_incidence0.73113488
91MP0001529_abnormal_vocalization0.72334377
92MP0005187_abnormal_penis_morphology0.71940691
93MP0003699_abnormal_female_reproductive0.71468696
94MP0006292_abnormal_olfactory_placode0.71005112
95MP0009672_abnormal_birth_weight0.70596114
96MP0004215_abnormal_myocardial_fiber0.70484909
97MP0005670_abnormal_white_adipose0.70002821
98MP0001119_abnormal_female_reproductive0.69911692
99MP0008873_increased_physiological_sensi0.68020222
100MP0002398_abnormal_bone_marrow0.67960512
101MP0004808_abnormal_hematopoietic_stem0.67016618
102MP0000689_abnormal_spleen_morphology0.66520819
103MP0000350_abnormal_cell_proliferation0.65375997
104MP0005408_hypopigmentation0.65360309
105MP0000604_amyloidosis0.65209228
106MP0005395_other_phenotype0.65099881
107MP0010307_abnormal_tumor_latency0.64712683
108MP0009053_abnormal_anal_canal0.64712233
109MP0009333_abnormal_splenocyte_physiolog0.64541633
110MP0005023_abnormal_wound_healing0.64480992
111MP0000358_abnormal_cell_content/0.63977989
112MP0008932_abnormal_embryonic_tissue0.60231792
113MP0002080_prenatal_lethality0.59666121
114MP0001672_abnormal_embryogenesis/_devel0.59402956
115MP0005380_embryogenesis_phenotype0.59402956
116MP0010368_abnormal_lymphatic_system0.58754489
117MP0003221_abnormal_cardiomyocyte_apopto0.58403302
118MP0005075_abnormal_melanosome_morpholog0.58028926
119MP0003724_increased_susceptibility_to0.56968942
120MP0002722_abnormal_immune_system0.56199687
121MP0005084_abnormal_gallbladder_morpholo0.56139147
122MP0001845_abnormal_inflammatory_respons0.55281792
123MP0002088_abnormal_embryonic_growth/wei0.54585114
124MP0002254_reproductive_system_inflammat0.54574847
125MP0002086_abnormal_extraembryonic_tissu0.54450079
126MP0003984_embryonic_growth_retardation0.54223530
127MP0004147_increased_porphyrin_level0.53161847
128MP0000685_abnormal_immune_system0.52428384
129MP0009785_altered_susceptibility_to0.52362263
130MP0001915_intracranial_hemorrhage0.51880697
131MP0001697_abnormal_embryo_size0.50397317
132MP0000313_abnormal_cell_death0.50008281
133MP0000490_abnormal_crypts_of0.49301845
134MP0002970_abnormal_white_adipose0.48970293
135MP0003786_premature_aging0.48829455
136MP0001756_abnormal_urination0.48424294

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)6.33487826
2Intrahepatic cholestasis (HP:0001406)6.14417723
3Abnormality of monocarboxylic acid metabolism (HP:0010996)6.07892969
4Hypobetalipoproteinemia (HP:0003563)5.92044144
5Deep venous thrombosis (HP:0002625)5.84757493
6Prolonged partial thromboplastin time (HP:0003645)5.23929543
7Xanthomatosis (HP:0000991)5.13757123
8Hyperlipoproteinemia (HP:0010980)4.57145614
9Abnormality of pyrimidine metabolism (HP:0004353)4.47264587
10Hyperglycinemia (HP:0002154)4.38254673
11Hyperammonemia (HP:0001987)4.26344446
12Hypolipoproteinemia (HP:0010981)4.17878629
13Complement deficiency (HP:0004431)4.11448395
14Abnormality of methionine metabolism (HP:0010901)3.93849587
15Abnormality of sulfur amino acid metabolism (HP:0004339)3.87605956
16Hyperglycinuria (HP:0003108)3.79810909
17Abnormality of the common coagulation pathway (HP:0010990)3.77537959
18Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.76551832
19Abnormality of glycine metabolism (HP:0010895)3.74426820
20Abnormality of serine family amino acid metabolism (HP:0010894)3.74426820
21Abnormality of aspartate family amino acid metabolism (HP:0010899)3.60315639
22Joint hemorrhage (HP:0005261)3.53279416
23Chromsome breakage (HP:0040012)3.52328940
24Chromosomal breakage induced by crosslinking agents (HP:0003221)3.46605111
25Ketosis (HP:0001946)3.40464842
26Abnormality of the intrinsic pathway (HP:0010989)3.40280879
27Fat malabsorption (HP:0002630)3.36709766
28Hypoalphalipoproteinemia (HP:0003233)3.34008663
29Abnormality of serum amino acid levels (HP:0003112)3.32784131
30Epidermoid cyst (HP:0200040)3.25388176
31Hypoglycemic coma (HP:0001325)3.20048274
32Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.16268369
33Abnormality of glutamine family amino acid metabolism (HP:0010902)3.13775347
34Hyperbilirubinemia (HP:0002904)3.13457107
35Abnormality of complement system (HP:0005339)3.12640827
36Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.07311434
37Abnormality of alanine metabolism (HP:0010916)3.07311434
38Hyperalaninemia (HP:0003348)3.07311434
39Abnormality of fatty-acid metabolism (HP:0004359)3.04035797
40Abnormality of nucleobase metabolism (HP:0010932)2.99848307
41Acute encephalopathy (HP:0006846)2.97684457
42Spastic diplegia (HP:0001264)2.92616791
43Hypercholesterolemia (HP:0003124)2.90120574
44Hepatocellular necrosis (HP:0001404)2.85126254
45Delayed CNS myelination (HP:0002188)2.84209694
46Increased CSF lactate (HP:0002490)2.77652574
47Type I transferrin isoform profile (HP:0003642)2.71285058
48Spontaneous abortion (HP:0005268)2.69951233
49Hepatic necrosis (HP:0002605)2.69769196
50Oral leukoplakia (HP:0002745)2.67051560
51Steatorrhea (HP:0002570)2.66896290
52Abnormality of the preputium (HP:0100587)2.66477266
53Abnormal protein glycosylation (HP:0012346)2.66419218
54Abnormal glycosylation (HP:0012345)2.66419218
55Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.66419218
56Abnormal protein N-linked glycosylation (HP:0012347)2.66419218
57Lipid accumulation in hepatocytes (HP:0006561)2.66156873
58Lethargy (HP:0001254)2.66100364
59Increased serum lactate (HP:0002151)2.65621443
60Hepatocellular carcinoma (HP:0001402)2.63167255
61Dicarboxylic aciduria (HP:0003215)2.62074778
62Abnormality of dicarboxylic acid metabolism (HP:0010995)2.62074778
63Abnormality of chromosome stability (HP:0003220)2.58743687
64Meckel diverticulum (HP:0002245)2.57401506
65Abnormality of the ileum (HP:0001549)2.57023378
66Aplasia/Hypoplasia of the uvula (HP:0010293)2.54940122
67Mitochondrial inheritance (HP:0001427)2.54868465
68Conjugated hyperbilirubinemia (HP:0002908)2.53367185
69Abnormality of the pons (HP:0007361)2.53180595
70Abnormal mitochondria in muscle tissue (HP:0008316)2.52948638
71Acute necrotizing encephalopathy (HP:0006965)2.52736881
72Hypoplasia of the pons (HP:0012110)2.52595783
73Premature ovarian failure (HP:0008209)2.50009386
74Acanthocytosis (HP:0001927)2.49723741
75Myocardial infarction (HP:0001658)2.42310799
76Abnormality of iron homeostasis (HP:0011031)2.42184344
77Gout (HP:0001997)2.39557081
78Hypochromic microcytic anemia (HP:0004840)2.38811624
79Paralysis (HP:0003470)2.38356298
80Metabolic acidosis (HP:0001942)2.34945971
81Duplicated collecting system (HP:0000081)2.34245555
82Microvesicular hepatic steatosis (HP:0001414)2.33658986
83Abnormality of transition element cation homeostasis (HP:0011030)2.33064859
84Abnormal cartilage morphology (HP:0002763)2.28402268
85Brushfield spots (HP:0001088)2.28341049
86Cerebral hypomyelination (HP:0006808)2.27379006
87Megaloblastic anemia (HP:0001889)2.26254341
88Abnormality of purine metabolism (HP:0004352)2.26140167
89Increased serum ferritin (HP:0003281)2.25626448
90Poikilocytosis (HP:0004447)2.25268272
91Multiple enchondromatosis (HP:0005701)2.24613343
92Abnormality of the heme biosynthetic pathway (HP:0010472)2.23649580
93Cerebral edema (HP:0002181)2.23218232
94Lactic acidosis (HP:0003128)2.22316870
95Hypoplasia of the uterus (HP:0000013)2.19316307
96Abnormality of DNA repair (HP:0003254)2.18352522
97Increased muscle lipid content (HP:0009058)2.16639150
98Small intestinal stenosis (HP:0012848)2.16456908
99Duodenal stenosis (HP:0100867)2.16456908
100Pancreatic islet-cell hyperplasia (HP:0004510)2.15801409
101Opisthotonus (HP:0002179)2.14371791
102Increased hepatocellular lipid droplets (HP:0006565)2.13863544
103Abnormality of the renal collecting system (HP:0004742)2.13339987
104Sloping forehead (HP:0000340)2.12758560
105Nausea (HP:0002018)2.10784082
106Irritability (HP:0000737)2.09489597
107Progressive macrocephaly (HP:0004481)2.08932818
108Thrombophlebitis (HP:0004418)2.07583235
109Gingival bleeding (HP:0000225)2.05992714
110Increased intramyocellular lipid droplets (HP:0012240)2.05588314
111Pancytopenia (HP:0001876)2.01953439
112Absent thumb (HP:0009777)2.00998912
113Aplasia/hypoplasia of the uterus (HP:0008684)2.00943775
114Reduced antithrombin III activity (HP:0001976)2.00403691
115Ketoacidosis (HP:0001993)1.99027417
116Pancreatic cysts (HP:0001737)1.97900185
117Squamous cell carcinoma (HP:0002860)1.97165488
118Reticulocytosis (HP:0001923)1.96425511
119Pallor (HP:0000980)1.93695556
120Neonatal onset (HP:0003623)1.93466181
121Malnutrition (HP:0004395)1.92465402
122Esophageal varix (HP:0002040)1.91679242
123Systemic lupus erythematosus (HP:0002725)1.91110195
124Myelodysplasia (HP:0002863)1.90643964
125Abnormality of cells of the erythroid lineage (HP:0012130)1.90590663
126Generalized aminoaciduria (HP:0002909)1.89958609
127Cholecystitis (HP:0001082)1.89173725
128Abnormal gallbladder physiology (HP:0012438)1.89173725
129Abnormal number of erythroid precursors (HP:0012131)1.88924687
130Birth length less than 3rd percentile (HP:0003561)1.88921389
131Late onset (HP:0003584)1.88494608
132Horseshoe kidney (HP:0000085)1.88363260
133Skin nodule (HP:0200036)1.87518061
134Clubbing of toes (HP:0100760)1.86355833
135Cholelithiasis (HP:0001081)1.86103092
136Hypergonadotropic hypogonadism (HP:0000815)1.85312365
137Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.84716278
138Decreased activity of mitochondrial respiratory chain (HP:0008972)1.84716278
139Pancreatitis (HP:0001733)1.84711286
140Elevated hepatic transaminases (HP:0002910)1.84368997
141Abnormality of the duodenum (HP:0002246)1.83169115
142Abnormal gallbladder morphology (HP:0012437)1.82307305
143Recurrent gram-negative bacterial infections (HP:0005420)1.81233869
144Type II lissencephaly (HP:0007260)1.80291448
145CNS hypomyelination (HP:0003429)1.79929290
146Cerebral palsy (HP:0100021)1.79885333
147Abnormality of reticulocytes (HP:0004312)1.78085563
148Ileus (HP:0002595)1.77498536
149Tubulointerstitial nephritis (HP:0001970)1.76415837
150Vomiting (HP:0002013)1.75721609
151Hypertriglyceridemia (HP:0002155)1.74573724
152Menorrhagia (HP:0000132)1.74492234
153Ureteral duplication (HP:0000073)1.74132458
154Pancreatic fibrosis (HP:0100732)1.74037391
155Progressive muscle weakness (HP:0003323)1.73958499
156Renal cortical cysts (HP:0000803)1.73610845
157Macrocytic anemia (HP:0001972)1.70870211
158Epistaxis (HP:0000421)1.68345576
159Increased serum pyruvate (HP:0003542)1.68110167
160Abnormality of glycolysis (HP:0004366)1.68110167
161Ragged-red muscle fibers (HP:0003200)1.66414898
162Aplastic anemia (HP:0001915)1.65232221
163Glomerulonephritis (HP:0000099)1.64608710
164Spastic paraparesis (HP:0002313)1.64207080
165CNS demyelination (HP:0007305)1.63390196

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK4.76336048
2WEE13.71594070
3BUB13.61870698
4EIF2AK12.91275968
5NME22.68161946
6VRK22.66751101
7STK162.64040900
8ERN12.54207319
9MST42.50377040
10FLT32.25353877
11NUAK12.22596394
12TAF12.19991292
13CDC72.18455459
14BMPR1B2.09727429
15FGFR42.05804041
16ACVR1B1.92529705
17FRK1.90578812
18NEK21.81353041
19TSSK61.76055510
20BRSK21.73383274
21MAP4K21.72327782
22NME11.71128330
23SIK11.66590832
24PINK11.65984575
25KDR1.63702294
26NEK11.62644350
27PKN21.62466004
28PLK41.61337843
29TESK21.58224855
30EIF2AK31.55174406
31MAP3K111.52994217
32MAP4K11.47777697
33RPS6KB21.44533190
34DYRK31.44410741
35TTK1.42913937
36CDK41.41232658
37PIM21.39222329
38EEF2K1.35093356
39MKNK11.34650854
40RPS6KA41.33408929
41TYK21.31288330
42PDK21.31287690
43MAP3K101.30920300
44EPHA21.30856242
45MAP2K31.28831523
46RPS6KA51.28355923
47CDK71.24656152
48PLK11.23235794
49MAP3K81.23220412
50OBSCN1.20791653
51CDK81.18676365
52MAPK111.17165652
53TRIB31.15501681
54SCYL21.15083084
55ERBB41.13712581
56STK101.13344958
57SRPK11.03051646
58AURKB1.02275300
59TAOK31.02236538
60TGFBR11.01236264
61ABL21.00295347
62IRAK30.98301418
63GRK60.96637115
64ATR0.96635791
65MKNK20.96580603
66VRK10.96342855
67CLK10.96022188
68MARK30.95031327
69CCNB10.91034634
70PIM10.89511770
71CDK30.87506437
72INSRR0.85709114
73LRRK20.85535489
74TBK10.85107112
75BRSK10.84760395
76TAOK20.84601720
77AURKA0.83385229
78MAP3K30.81809408
79JAK30.81426427
80ZAP700.80444962
81TRIM280.78553179
82CSNK1G10.75452154
83KIT0.75417663
84PASK0.73906737
85MAPKAPK50.73635738
86PAK40.72456934
87ADRBK20.72211230
88CSNK1G30.71140048
89CDK60.70627622
90GRK10.70596152
91TLK10.69883807
92EIF2AK20.68674677
93MAPKAPK30.68339558
94CSF1R0.68254212
95CSNK1A1L0.67941960
96RAF10.61268787
97CSNK2A20.61102332
98MAP3K50.60692019
99CHEK10.60043303
100PLK30.59594765
101NEK90.59182158
102BCR0.58838033
103CHEK20.57271750
104JAK20.56770217
105BTK0.56209932
106TRPM70.56073172
107STK30.55878191
108STK40.55201142
109CSNK2A10.53460145
110MAPK40.53360335
111MAP2K70.52791063
112IKBKB0.51418443
113DAPK10.51183679
114MTOR0.51058876
115MELK0.46519355
116PIK3CG0.45771329
117CDK90.44232323
118CDK20.44060683
119LATS10.43649368
120BLK0.43644803
121DYRK20.42719277
122RPS6KB10.42356735
123CDK10.41867924
124MAP2K20.41612132
125MST1R0.39600299
126PRKCQ0.39018259
127TEC0.38499427
128CSNK1G20.37908267
129PAK10.36511787
130DAPK30.36386325
131ZAK0.35829683
132BRAF0.35809093
133PTK60.35693212
134TAOK10.35439590
135ATM0.35192721
136LATS20.34613834
137PRKCI0.33152626
138PAK20.33093967
139PBK0.32604326
140AKT20.31392748
141WNK30.30514035
142CDK120.29660590
143CSNK1E0.27643631
144PRKAA20.27268215
145PRKDC0.25656338

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001203.75964190
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.85359631
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.83585831
4Nitrogen metabolism_Homo sapiens_hsa009102.70494661
5Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.67295699
6Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.54953529
7Arginine biosynthesis_Homo sapiens_hsa002202.48787013
8Complement and coagulation cascades_Homo sapiens_hsa046102.16676126
9One carbon pool by folate_Homo sapiens_hsa006702.13086547
10Drug metabolism - other enzymes_Homo sapiens_hsa009832.13061730
11Tryptophan metabolism_Homo sapiens_hsa003802.10709626
12Fatty acid degradation_Homo sapiens_hsa000712.02629397
13Folate biosynthesis_Homo sapiens_hsa007901.98551692
14Pentose and glucuronate interconversions_Homo sapiens_hsa000401.97010961
15Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.95399692
16Selenocompound metabolism_Homo sapiens_hsa004501.94634610
17Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.92742018
18Cysteine and methionine metabolism_Homo sapiens_hsa002701.88972028
19Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.83544567
20Peroxisome_Homo sapiens_hsa041461.74636634
212-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.71890015
22DNA replication_Homo sapiens_hsa030301.69519256
23Biosynthesis of amino acids_Homo sapiens_hsa012301.68347983
24Vitamin B6 metabolism_Homo sapiens_hsa007501.67637733
25Sulfur relay system_Homo sapiens_hsa041221.61961855
26Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.61580888
27Caffeine metabolism_Homo sapiens_hsa002321.56801521
28Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.55380859
29Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.54695863
30Chemical carcinogenesis_Homo sapiens_hsa052041.52077461
31Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.51973102
32Propanoate metabolism_Homo sapiens_hsa006401.51030971
33Butanoate metabolism_Homo sapiens_hsa006501.46018389
34beta-Alanine metabolism_Homo sapiens_hsa004101.45872551
35Cyanoamino acid metabolism_Homo sapiens_hsa004601.42800077
36Histidine metabolism_Homo sapiens_hsa003401.42436613
37Steroid hormone biosynthesis_Homo sapiens_hsa001401.41291103
38Retinol metabolism_Homo sapiens_hsa008301.34885487
39Staphylococcus aureus infection_Homo sapiens_hsa051501.34570058
40Carbon metabolism_Homo sapiens_hsa012001.33609791
41PPAR signaling pathway_Homo sapiens_hsa033201.33157406
42Fatty acid metabolism_Homo sapiens_hsa012121.31329265
43Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.28592349
44* Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.27340644
45Proteasome_Homo sapiens_hsa030501.26321177
46Pentose phosphate pathway_Homo sapiens_hsa000301.22256656
47Phenylalanine metabolism_Homo sapiens_hsa003601.21902543
48Pyrimidine metabolism_Homo sapiens_hsa002401.17894642
49Pyruvate metabolism_Homo sapiens_hsa006201.17891418
50Mismatch repair_Homo sapiens_hsa034301.17685897
51Ribosome_Homo sapiens_hsa030101.17026039
52Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.13454405
53RNA polymerase_Homo sapiens_hsa030201.08234415
54Tyrosine metabolism_Homo sapiens_hsa003501.07961223
55Oxidative phosphorylation_Homo sapiens_hsa001901.07006363
56Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.03302145
57Parkinsons disease_Homo sapiens_hsa050121.01258358
58Arginine and proline metabolism_Homo sapiens_hsa003300.98751670
59Fat digestion and absorption_Homo sapiens_hsa049750.95274840
60mRNA surveillance pathway_Homo sapiens_hsa030150.94578779
61Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.92333153
62Starch and sucrose metabolism_Homo sapiens_hsa005000.90834365
63Glutathione metabolism_Homo sapiens_hsa004800.89407046
64RNA transport_Homo sapiens_hsa030130.86857746
65Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.85368227
66Bile secretion_Homo sapiens_hsa049760.85286029
67Protein export_Homo sapiens_hsa030600.82210870
68Base excision repair_Homo sapiens_hsa034100.82209172
69Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.82179178
70Vitamin digestion and absorption_Homo sapiens_hsa049770.81772074
71Fatty acid elongation_Homo sapiens_hsa000620.79325895
72ABC transporters_Homo sapiens_hsa020100.78611120
73Spliceosome_Homo sapiens_hsa030400.78115177
74Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.75728261
75Steroid biosynthesis_Homo sapiens_hsa001000.74673400
76Huntingtons disease_Homo sapiens_hsa050160.73369925
77Nucleotide excision repair_Homo sapiens_hsa034200.72334533
78Sulfur metabolism_Homo sapiens_hsa009200.67791980
79Maturity onset diabetes of the young_Homo sapiens_hsa049500.64202002
80Primary immunodeficiency_Homo sapiens_hsa053400.63255195
81Lysine degradation_Homo sapiens_hsa003100.62174562
82Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.61742269
83Homologous recombination_Homo sapiens_hsa034400.60444728
84Metabolic pathways_Homo sapiens_hsa011000.57907504
85N-Glycan biosynthesis_Homo sapiens_hsa005100.55616388
86Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.53441763
87Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.52653360
88Galactose metabolism_Homo sapiens_hsa000520.49600533
89Glycerolipid metabolism_Homo sapiens_hsa005610.48819468
90Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.48279748
91alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.47527970
92Fructose and mannose metabolism_Homo sapiens_hsa000510.46125515
93Cell cycle_Homo sapiens_hsa041100.45875622
94Regulation of autophagy_Homo sapiens_hsa041400.41268363
95Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.38495633
96Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.38413214
97Purine metabolism_Homo sapiens_hsa002300.37961512
98Systemic lupus erythematosus_Homo sapiens_hsa053220.35128374
99RNA degradation_Homo sapiens_hsa030180.32739577
100Arachidonic acid metabolism_Homo sapiens_hsa005900.32309978
101Alcoholism_Homo sapiens_hsa050340.30916585
102Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.30299682
103Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.27956726
104p53 signaling pathway_Homo sapiens_hsa041150.27822770
105Alzheimers disease_Homo sapiens_hsa050100.27701041
106Oocyte meiosis_Homo sapiens_hsa041140.27593861
107Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.27492281
108Non-homologous end-joining_Homo sapiens_hsa034500.23166459
109Fatty acid biosynthesis_Homo sapiens_hsa000610.21918886
110Basal transcription factors_Homo sapiens_hsa030220.17087129
111Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.16899790
112Fanconi anemia pathway_Homo sapiens_hsa034600.16195270
113Prion diseases_Homo sapiens_hsa050200.15829362
114Glycerophospholipid metabolism_Homo sapiens_hsa005640.13677950
115Legionellosis_Homo sapiens_hsa051340.12861759
116Linoleic acid metabolism_Homo sapiens_hsa005910.12803239
117Herpes simplex infection_Homo sapiens_hsa051680.11477916
118Adipocytokine signaling pathway_Homo sapiens_hsa049200.10923822

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