RCCD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic chromosome condensation (GO:0007076)5.78803283
2DNA unwinding involved in DNA replication (GO:0006268)5.28503724
3mitotic sister chromatid segregation (GO:0000070)5.08428178
4ribosomal small subunit biogenesis (GO:0042274)4.99268806
5DNA replication checkpoint (GO:0000076)4.95186778
6DNA strand elongation involved in DNA replication (GO:0006271)4.85086227
7regulation of translational fidelity (GO:0006450)4.78500822
8nuclear pore complex assembly (GO:0051292)4.72651459
9DNA strand elongation (GO:0022616)4.69479755
10sister chromatid segregation (GO:0000819)4.66786239
11DNA replication initiation (GO:0006270)4.60274675
12protein localization to chromosome, centromeric region (GO:0071459)4.42268075
13telomere maintenance via semi-conservative replication (GO:0032201)4.41777239
14viral transcription (GO:0019083)4.24532328
15nuclear pore organization (GO:0006999)4.19291272
16proline biosynthetic process (GO:0006561)4.15811027
17DNA topological change (GO:0006265)4.12818000
18translational termination (GO:0006415)4.06060788
19protein localization to kinetochore (GO:0034501)4.03395153
20kinetochore assembly (GO:0051382)4.00556031
21DNA synthesis involved in DNA repair (GO:0000731)3.92432061
22negative regulation of DNA-dependent DNA replication (GO:2000104)3.86297488
23regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.84114433
24kinetochore organization (GO:0051383)3.81650444
25DNA ligation (GO:0006266)3.70572881
26chromosome condensation (GO:0030261)3.69717324
27regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.65407702
28microtubule depolymerization (GO:0007019)3.64618048
29telomere maintenance via recombination (GO:0000722)3.62793050
30DNA damage response, detection of DNA damage (GO:0042769)3.62726030
31mitotic nuclear envelope disassembly (GO:0007077)3.61924417
32chromosome organization involved in meiosis (GO:0070192)3.57191476
33ribosomal large subunit biogenesis (GO:0042273)3.56369083
34mitotic recombination (GO:0006312)3.53354521
35pore complex assembly (GO:0046931)3.52550337
36regulation of nuclear cell cycle DNA replication (GO:0033262)3.52390240
37mitotic sister chromatid cohesion (GO:0007064)3.49844439
38maturation of SSU-rRNA (GO:0030490)3.46894052
39DNA duplex unwinding (GO:0032508)3.45629017
40chromosome segregation (GO:0007059)3.42134005
41formation of translation preinitiation complex (GO:0001731)3.40898949
42synapsis (GO:0007129)3.40782288
43cotranslational protein targeting to membrane (GO:0006613)3.38108166
44DNA conformation change (GO:0071103)3.37473296
45transcription elongation from RNA polymerase III promoter (GO:0006385)3.37335946
46termination of RNA polymerase III transcription (GO:0006386)3.37335946
47nuclear envelope disassembly (GO:0051081)3.35417121
48membrane disassembly (GO:0030397)3.35417121
49DNA geometric change (GO:0032392)3.34499485
50SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.32166097
51sister chromatid cohesion (GO:0007062)3.32029218
52preassembly of GPI anchor in ER membrane (GO:0016254)3.31684496
53chromatin assembly (GO:0031497)3.31532383
54attachment of spindle microtubules to kinetochore (GO:0008608)3.31027272
55DNA packaging (GO:0006323)3.30837593
56folic acid metabolic process (GO:0046655)3.29944727
57limb bud formation (GO:0060174)3.29894485
58protein targeting to ER (GO:0045047)3.29587431
59presynaptic membrane assembly (GO:0097105)3.27213120
60regulation of translational termination (GO:0006449)3.26252618
61regulation of mitotic spindle organization (GO:0060236)3.24576362
62chromatin assembly or disassembly (GO:0006333)3.24058189
63regulation of sister chromatid cohesion (GO:0007063)3.23593351
64cellular protein complex disassembly (GO:0043624)3.22422942
65regulation of translational elongation (GO:0006448)3.20027719
66DNA replication-dependent nucleosome organization (GO:0034723)3.18404789
67DNA replication-dependent nucleosome assembly (GO:0006335)3.18404789
68establishment of protein localization to endoplasmic reticulum (GO:0072599)3.17543673
69synaptonemal complex assembly (GO:0007130)3.16276792
70neuron cell-cell adhesion (GO:0007158)3.15800779
71protein localization to chromosome (GO:0034502)3.15626111
72positive regulation of chromosome segregation (GO:0051984)3.14226396
73negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.14055846
74regulation of chromosome segregation (GO:0051983)3.13596810
75ribosomal small subunit assembly (GO:0000028)3.12738411
76negative regulation of chromosome segregation (GO:0051985)3.11584076
77GTP biosynthetic process (GO:0006183)3.10587168
78GPI anchor biosynthetic process (GO:0006506)3.10028718
79mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.07047257
80viral life cycle (GO:0019058)3.06958624
81nucleotide-excision repair, DNA gap filling (GO:0006297)3.06644436
82CENP-A containing nucleosome assembly (GO:0034080)3.06456071
83protein localization to endoplasmic reticulum (GO:0070972)3.05390524
84regulation of centrosome cycle (GO:0046605)3.05185039
85presynaptic membrane organization (GO:0097090)3.03958635
86protoporphyrinogen IX metabolic process (GO:0046501)3.01023277
87regulation of spindle organization (GO:0090224)3.00164144
88developmental pigmentation (GO:0048066)2.99911978
89regulation of DNA-dependent DNA replication (GO:0090329)2.99142675
90NADH dehydrogenase complex assembly (GO:0010257)2.98229721
91mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.98229721
92mitochondrial respiratory chain complex I assembly (GO:0032981)2.98229721
93translational elongation (GO:0006414)2.97945598
94protein complex biogenesis (GO:0070271)2.97076781
95peptidyl-arginine omega-N-methylation (GO:0035247)2.96687960
96ribosome biogenesis (GO:0042254)2.95630327
97nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.95231068
98chromatin remodeling at centromere (GO:0031055)2.92136397
99spindle checkpoint (GO:0031577)2.91198656
100mitotic spindle assembly checkpoint (GO:0007094)2.91004171
101neuron fate determination (GO:0048664)2.90517320
102mitotic spindle checkpoint (GO:0071174)2.89942126
103negative regulation of mitotic sister chromatid separation (GO:2000816)2.89846355
104negative regulation of sister chromatid segregation (GO:0033046)2.89846355
105negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.89846355
106negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.89846355
107negative regulation of mitotic sister chromatid segregation (GO:0033048)2.89846355
108nuclear envelope organization (GO:0006998)2.89542720
109positive regulation of DNA-dependent DNA replication (GO:2000105)2.86267103
110spindle assembly checkpoint (GO:0071173)2.84692976
111regulation of pigment cell differentiation (GO:0050932)2.84378174
112regulation of RNA export from nucleus (GO:0046831)2.83459922
113proline metabolic process (GO:0006560)2.83410154
114regulation of histone H3-K9 methylation (GO:0051570)2.81983502
115telomere maintenance via telomere lengthening (GO:0010833)2.81971821
116long-chain fatty acid biosynthetic process (GO:0042759)2.81843488
117positive regulation of cellular response to oxidative stress (GO:1900409)2.81736789
118positive regulation of response to oxidative stress (GO:1902884)2.81736789
119spinal cord association neuron differentiation (GO:0021527)2.81292369
120chromosome organization (GO:0051276)2.81230505
121regulation of somitogenesis (GO:0014807)2.80698576
122regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.79640285
123regulation of mitotic metaphase/anaphase transition (GO:0030071)2.79640285
124regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.79213617
125microtubule polymerization or depolymerization (GO:0031109)2.79140089
126keratinocyte development (GO:0003334)2.78329780
127regulation of mitotic sister chromatid segregation (GO:0033047)2.77752076
128regulation of sister chromatid segregation (GO:0033045)2.77752076
129regulation of mitotic sister chromatid separation (GO:0010965)2.77752076
130folic acid-containing compound biosynthetic process (GO:0009396)2.77251994
131spliceosomal complex assembly (GO:0000245)2.77228780
132axon ensheathment in central nervous system (GO:0032291)2.76913457
133central nervous system myelination (GO:0022010)2.76913457
134establishment of integrated proviral latency (GO:0075713)2.74610738
135otic vesicle formation (GO:0030916)2.74118983
136regulation of double-strand break repair via homologous recombination (GO:0010569)2.74016620
137establishment of chromosome localization (GO:0051303)2.73611908
138regulation of timing of cell differentiation (GO:0048505)2.71940023
139protein complex disassembly (GO:0043241)2.71319338
140transcription elongation from RNA polymerase I promoter (GO:0006362)2.70452698
141meiotic cell cycle process (GO:1903046)2.69460475
142cell proliferation in forebrain (GO:0021846)2.68446855
143translational initiation (GO:0006413)2.66709375
144energy coupled proton transport, down electrochemical gradient (GO:0015985)2.61549875
145ATP synthesis coupled proton transport (GO:0015986)2.61549875
146GPI anchor metabolic process (GO:0006505)2.61372461
147UTP biosynthetic process (GO:0006228)2.61370092
148regulation of development, heterochronic (GO:0040034)2.58949516
149termination of RNA polymerase I transcription (GO:0006363)2.57225554
150startle response (GO:0001964)2.56187174
151mitochondrial respiratory chain complex assembly (GO:0033108)2.55777616
152mRNA splice site selection (GO:0006376)2.55343284
153mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.55075416
154nonmotile primary cilium assembly (GO:0035058)2.54696306
155macromolecular complex disassembly (GO:0032984)2.54252448
156meiotic chromosome segregation (GO:0045132)2.53651606
157DNA strand renaturation (GO:0000733)2.51617984
158spliceosomal snRNP assembly (GO:0000387)2.50575660
159neuron remodeling (GO:0016322)2.50396699
160positive regulation of protein homodimerization activity (GO:0090073)2.49738179
161lateral sprouting from an epithelium (GO:0060601)2.49533783
162lymphoid progenitor cell differentiation (GO:0002320)2.49436174
163mitotic metaphase plate congression (GO:0007080)2.48141480
164single strand break repair (GO:0000012)2.45067703
165ribonucleoprotein complex biogenesis (GO:0022613)2.44544002
166dopamine transport (GO:0015872)2.43263861
167metaphase plate congression (GO:0051310)2.42693225
168regulation of DNA endoreduplication (GO:0032875)2.39720977
169maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.34701382
170RNA capping (GO:0036260)2.34449762
1717-methylguanosine RNA capping (GO:0009452)2.34449762
172cell differentiation in spinal cord (GO:0021515)2.32708865
1737-methylguanosine mRNA capping (GO:0006370)2.32520592
174cellular component biogenesis (GO:0044085)2.31960026
175histone exchange (GO:0043486)2.29977327
176translation (GO:0006412)2.29932004
177dopamine biosynthetic process (GO:0042416)2.29900827
178spinal cord motor neuron differentiation (GO:0021522)2.29062605
179tRNA methylation (GO:0030488)2.28850394
180DNA replication-independent nucleosome assembly (GO:0006336)2.28388355
181DNA replication-independent nucleosome organization (GO:0034724)2.28388355
182proteasome assembly (GO:0043248)2.28171114
183rRNA processing (GO:0006364)2.28012387
184negative regulation of execution phase of apoptosis (GO:1900118)2.27971435

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.54837841
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.54744582
3GBX2_23144817_ChIP-Seq_PC3_Human3.27642725
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.24007891
5CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.13415859
6HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.96914707
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.90414661
8MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.79953593
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.67068367
10XRN2_22483619_ChIP-Seq_HELA_Human2.56312024
11* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.42004962
12BMI1_23680149_ChIP-Seq_NPCS_Mouse2.36510847
13MYC_22102868_ChIP-Seq_BL_Human2.36018272
14E2F1_21310950_ChIP-Seq_MCF-7_Human2.34285759
15FUS_26573619_Chip-Seq_HEK293_Human2.30905785
16ZFP57_27257070_Chip-Seq_ESCs_Mouse2.27096706
17CBX2_27304074_Chip-Seq_ESCs_Mouse2.25643568
18PCGF2_27294783_Chip-Seq_ESCs_Mouse2.22908626
19MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.21215003
20E2F7_22180533_ChIP-Seq_HELA_Human2.19203919
21FLI1_27457419_Chip-Seq_LIVER_Mouse2.18584936
22KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.13646368
23POU5F1_16153702_ChIP-ChIP_HESCs_Human2.10032937
24TAF15_26573619_Chip-Seq_HEK293_Human2.09690741
25VDR_21846776_ChIP-Seq_THP-1_Human2.09503821
26DCP1A_22483619_ChIP-Seq_HELA_Human2.09214761
27TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.07780496
28* FOXM1_23109430_ChIP-Seq_U2OS_Human2.06798730
29POU3F2_20337985_ChIP-ChIP_501MEL_Human2.01995694
30DACH1_20351289_ChIP-Seq_MDA-MB-231_Human2.01966222
31JARID2_20064375_ChIP-Seq_MESCs_Mouse2.01876696
32E2F4_17652178_ChIP-ChIP_JURKAT_Human1.98339720
33CREB1_15753290_ChIP-ChIP_HEK293T_Human1.92972824
34THAP11_20581084_ChIP-Seq_MESCs_Mouse1.92415755
35NELFA_20434984_ChIP-Seq_ESCs_Mouse1.92258840
36POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.91870858
37IRF1_19129219_ChIP-ChIP_H3396_Human1.91492500
38EZH2_27304074_Chip-Seq_ESCs_Mouse1.90120426
39CTBP1_25329375_ChIP-Seq_LNCAP_Human1.88555922
40AR_21909140_ChIP-Seq_LNCAP_Human1.85499111
41EWS_26573619_Chip-Seq_HEK293_Human1.85223115
42CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.82970290
43VDR_22108803_ChIP-Seq_LS180_Human1.81413024
44EED_16625203_ChIP-ChIP_MESCs_Mouse1.79624671
45HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.77399058
46* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.76433638
47TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.75987433
48SUZ12_27294783_Chip-Seq_NPCs_Mouse1.74709926
49GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.71168543
50GABP_19822575_ChIP-Seq_HepG2_Human1.70584062
51NFE2_27457419_Chip-Seq_LIVER_Mouse1.69634350
52MYCN_18555785_ChIP-Seq_MESCs_Mouse1.69103912
53EGR1_19374776_ChIP-ChIP_THP-1_Human1.66615827
54RNF2_27304074_Chip-Seq_NSC_Mouse1.66072660
55* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.62149337
56HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.60195463
57* KDM5A_27292631_Chip-Seq_BREAST_Human1.58653661
58NANOG_18555785_Chip-Seq_ESCs_Mouse1.58240366
59PCGF2_27294783_Chip-Seq_NPCs_Mouse1.58192341
60EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.57311643
61* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.56478401
62ESR1_15608294_ChIP-ChIP_MCF-7_Human1.55963152
63RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.51246170
64SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.50952789
65P300_19829295_ChIP-Seq_ESCs_Human1.50923147
66TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.48128322
67* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.47207607
68FOXP3_21729870_ChIP-Seq_TREG_Human1.46681507
69ZNF263_19887448_ChIP-Seq_K562_Human1.46634126
70SUZ12_18555785_Chip-Seq_ESCs_Mouse1.45142682
71E2F1_18555785_Chip-Seq_ESCs_Mouse1.43712418
72KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.42391306
73AR_21572438_ChIP-Seq_LNCaP_Human1.41642864
74EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.41585000
75P53_22387025_ChIP-Seq_ESCs_Mouse1.41531086
76TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.41444930
77* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.41270845
78GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.41192470
79CIITA_25753668_ChIP-Seq_RAJI_Human1.40712815
80EZH2_27294783_Chip-Seq_NPCs_Mouse1.40654015
81JARID2_20075857_ChIP-Seq_MESCs_Mouse1.40151681
82P300_18555785_Chip-Seq_ESCs_Mouse1.39278720
83PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.38484482
84CTBP2_25329375_ChIP-Seq_LNCAP_Human1.37575530
85EST1_17652178_ChIP-ChIP_JURKAT_Human1.37351285
86NMYC_18555785_Chip-Seq_ESCs_Mouse1.36021901
87ER_23166858_ChIP-Seq_MCF-7_Human1.35259233
88SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.35103633
89SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.33855559
90STAT3_18555785_Chip-Seq_ESCs_Mouse1.33523826
91CMYC_18555785_Chip-Seq_ESCs_Mouse1.32459990
92SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.32186907
93* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.31727453
94YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.31263109
95KLF4_18555785_ChIP-Seq_MESCs_Mouse1.30833257
96ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.29242612
97YY1_21170310_ChIP-Seq_MESCs_Mouse1.29193683
98PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.28948389
99PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.28917790
100TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.28605099
101LXR_22292898_ChIP-Seq_THP-1_Human1.27396621
102SMAD3_21741376_ChIP-Seq_EPCs_Human1.26659868
103PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.26303908
104CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.26136004
105GABP_17652178_ChIP-ChIP_JURKAT_Human1.25364899
106ZFX_18555785_Chip-Seq_ESCs_Mouse1.24911359
107* MYC_18555785_ChIP-Seq_MESCs_Mouse1.24857179
108NOTCH1_21737748_ChIP-Seq_TLL_Human1.24773682
109* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.23664017
110ELK1_19687146_ChIP-ChIP_HELA_Human1.23546926
111ERG_20887958_ChIP-Seq_HPC-7_Mouse1.22988054
112RUNX1_27457419_Chip-Seq_LIVER_Mouse1.22601093
113OCT4_18555785_Chip-Seq_ESCs_Mouse1.22386254
114SOX2_18555785_Chip-Seq_ESCs_Mouse1.22103505
115PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.22052053
116MYC_18940864_ChIP-ChIP_HL60_Human1.21050389
117SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.20790093
118POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.20604570
119TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20604570
120BP1_19119308_ChIP-ChIP_Hs578T_Human1.20463631
121CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.19952385
122P68_20966046_ChIP-Seq_HELA_Human1.19608000
123EZH2_18974828_ChIP-Seq_MESCs_Mouse1.19286367
124RNF2_18974828_ChIP-Seq_MESCs_Mouse1.19286367
125NANOG_18555785_ChIP-Seq_MESCs_Mouse1.18947381
126TP63_19390658_ChIP-ChIP_HaCaT_Human1.17512664
127KLF4_18555785_Chip-Seq_ESCs_Mouse1.15643325
128CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.14351196
129SOX2_16153702_ChIP-ChIP_HESCs_Human1.13296574
130ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.13006983
131RNF2_27304074_Chip-Seq_ESCs_Mouse1.12678191
132TOP2B_26459242_ChIP-Seq_MCF-7_Human1.12559118
133SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.11894026
134CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10902426
135NCOR1_26117541_ChIP-Seq_K562_Human1.10713446
136BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.10526379
137PIAS1_25552417_ChIP-Seq_VCAP_Human1.09331747
138ESRRB_18555785_Chip-Seq_ESCs_Mouse1.09162710
139SMAD1_18555785_Chip-Seq_ESCs_Mouse1.09136176
140FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.08875949
141ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.08715540
142TTF2_22483619_ChIP-Seq_HELA_Human1.07868692
143TET1_21451524_ChIP-Seq_MESCs_Mouse1.07834034
144KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.07318302
145PU1_27457419_Chip-Seq_LIVER_Mouse1.06193706
146RACK7_27058665_Chip-Seq_MCF-7_Human1.05046207
147PKCTHETA_26484144_Chip-Seq_BREAST_Human1.04150152
148MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.03988512
149KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.03801710
150CTCF_18555785_Chip-Seq_ESCs_Mouse1.03783490
151VDR_23849224_ChIP-Seq_CD4+_Human1.03380942
152SALL1_21062744_ChIP-ChIP_HESCs_Human1.03365108
153* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.02805410
154EZH2_27294783_Chip-Seq_ESCs_Mouse1.01923123
155ETS1_20019798_ChIP-Seq_JURKAT_Human1.00446138
156MYC_19079543_ChIP-ChIP_MESCs_Mouse1.00433431
157SRF_21415370_ChIP-Seq_HL-1_Mouse1.00393281
158FOXP1_21924763_ChIP-Seq_HESCs_Human0.99262708
159CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.97740433
160SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.97593645
161SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.96455467
162KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.96358472
163HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.95743551
164TBX5_21415370_ChIP-Seq_HL-1_Mouse0.92749133
165STAT3_1855785_ChIP-Seq_MESCs_Mouse0.90995383
166ELF1_20517297_ChIP-Seq_JURKAT_Human0.89008818
167CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.88444459
168PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.86896174
169PHF8_20622854_ChIP-Seq_HELA_Human0.86136341
170SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.85174260
171EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.84924155
172RARA_24833708_ChIP-Seq_LIVER_Mouse0.84479942
173GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.83978161
174CTCF_27219007_Chip-Seq_ERYTHROID_Human0.83620933
175SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.83454191
176* MAF_26560356_Chip-Seq_TH2_Human0.82633327
177ATF3_27146783_Chip-Seq_COLON_Human0.82048854
178MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.81706352
179HOXB4_20404135_ChIP-ChIP_EML_Mouse0.80359666
180NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.80273180
181SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.79910135

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation5.39253761
2MP0001188_hyperpigmentation3.93180644
3MP0004957_abnormal_blastocyst_morpholog3.67658601
4MP0006292_abnormal_olfactory_placode3.39144461
5MP0000566_synostosis3.11821041
6MP0003880_abnormal_central_pattern2.97679972
7MP0005409_darkened_coat_color2.77913321
8MP0005171_absent_coat_pigmentation2.74629241
9MP0002102_abnormal_ear_morphology2.72611924
10MP0003136_yellow_coat_color2.61928001
11MP0002277_abnormal_respiratory_mucosa2.26058239
12MP0003718_maternal_effect2.20776801
13MP0005423_abnormal_somatic_nervous2.16020144
14MP0004147_increased_porphyrin_level2.12850875
15MP0000015_abnormal_ear_pigmentation2.10565816
16MP0005174_abnormal_tail_pigmentation2.07425055
17MP0003787_abnormal_imprinting1.93684199
18MP0003938_abnormal_ear_development1.88987651
19MP0000350_abnormal_cell_proliferation1.86373467
20MP0008058_abnormal_DNA_repair1.83133839
21MP0009278_abnormal_bone_marrow1.78461567
22MP0010307_abnormal_tumor_latency1.77126169
23MP0008789_abnormal_olfactory_epithelium1.77124614
24MP0004381_abnormal_hair_follicle1.76258342
25MP0005076_abnormal_cell_differentiation1.73838550
26MP0002396_abnormal_hematopoietic_system1.73090880
27MP0002210_abnormal_sex_determination1.68145816
28MP0001905_abnormal_dopamine_level1.68111399
29MP0001730_embryonic_growth_arrest1.68087739
30MP0000049_abnormal_middle_ear1.66813012
31MP0002132_abnormal_respiratory_system1.63541767
32MP0005075_abnormal_melanosome_morpholog1.57310192
33MP0001486_abnormal_startle_reflex1.55473164
34MP0005380_embryogenesis_phenotype1.54868451
35MP0001672_abnormal_embryogenesis/_devel1.54868451
36MP0001697_abnormal_embryo_size1.52749738
37MP0003111_abnormal_nucleus_morphology1.51700321
38MP0000778_abnormal_nervous_system1.49593603
39MP0002877_abnormal_melanocyte_morpholog1.49444450
40MP0001529_abnormal_vocalization1.49200127
41MP0005394_taste/olfaction_phenotype1.48612853
42MP0005499_abnormal_olfactory_system1.48612853
43MP0002736_abnormal_nociception_after1.48441278
44MP0004742_abnormal_vestibular_system1.48310093
45MP0002938_white_spotting1.47146742
46MP0003941_abnormal_skin_development1.45918435
47MP0006035_abnormal_mitochondrial_morpho1.45427741
48MP0006276_abnormal_autonomic_nervous1.44575877
49MP0002080_prenatal_lethality1.44051389
50MP0000026_abnormal_inner_ear1.43330991
51MP0002638_abnormal_pupillary_reflex1.42964852
52MP0002249_abnormal_larynx_morphology1.40331866
53MP0003984_embryonic_growth_retardation1.40105897
54MP0008057_abnormal_DNA_replication1.39466605
55MP0001929_abnormal_gametogenesis1.38474407
56MP0000313_abnormal_cell_death1.36852126
57MP0000631_abnormal_neuroendocrine_gland1.34628717
58MP0010094_abnormal_chromosome_stability1.34197290
59MP0002088_abnormal_embryonic_growth/wei1.33747091
60MP0004185_abnormal_adipocyte_glucose1.33595538
61MP0002163_abnormal_gland_morphology1.31185057
62MP0001346_abnormal_lacrimal_gland1.30452044
63MP0005645_abnormal_hypothalamus_physiol1.25384349
64MP0001968_abnormal_touch/_nociception1.24801632
65MP0001986_abnormal_taste_sensitivity1.24656413
66MP0002572_abnormal_emotion/affect_behav1.23390836
67MP0009745_abnormal_behavioral_response1.23197958
68MP0000358_abnormal_cell_content/1.22249305
69MP0001145_abnormal_male_reproductive1.21336840
70MP0004233_abnormal_muscle_weight1.21189168
71MP0000762_abnormal_tongue_morphology1.20955296
72MP0002085_abnormal_embryonic_tissue1.19814867
73MP0001485_abnormal_pinna_reflex1.19706007
74MP0004197_abnormal_fetal_growth/weight/1.19553026
75MP0005501_abnormal_skin_physiology1.16715193
76MP0002735_abnormal_chemical_nociception1.15144274
77MP0000569_abnormal_digit_pigmentation1.14144278
78MP0005646_abnormal_pituitary_gland1.13600300
79MP0005379_endocrine/exocrine_gland_phen1.13085411
80MP0002751_abnormal_autonomic_nervous1.12603375
81MP0000653_abnormal_sex_gland1.12407204
82MP0004142_abnormal_muscle_tone1.12389870
83MP0002095_abnormal_skin_pigmentation1.12386595
84MP0000003_abnormal_adipose_tissue1.12317051
85MP0006036_abnormal_mitochondrial_physio1.12040818
86MP0002160_abnormal_reproductive_system1.10280259
87MP0002084_abnormal_developmental_patter1.09534993
88MP0004808_abnormal_hematopoietic_stem1.09161406
89MP0009672_abnormal_birth_weight1.08888172
90MP0001963_abnormal_hearing_physiology1.08807322
91MP0002557_abnormal_social/conspecific_i1.07931555
92MP0002184_abnormal_innervation1.07845327
93MP0005451_abnormal_body_composition1.07336547
94MP0003656_abnormal_erythrocyte_physiolo1.07026045
95MP0005551_abnormal_eye_electrophysiolog1.06800060
96MP0009780_abnormal_chondrocyte_physiolo1.06536854
97MP0002272_abnormal_nervous_system1.06123067
98MP0008932_abnormal_embryonic_tissue1.06059959
99MP0003698_abnormal_male_reproductive1.05870000
100MP0002019_abnormal_tumor_incidence1.05105257
101MP0002752_abnormal_somatic_nervous1.03542782
102MP0003315_abnormal_perineum_morphology1.02474532
103MP0003693_abnormal_embryo_hatching1.02467186
104MP0003937_abnormal_limbs/digits/tail_de1.01711298
105MP0003699_abnormal_female_reproductive0.99488832
106MP0005360_urolithiasis0.99393987
107MP0000372_irregular_coat_pigmentation0.98907314
108MP0005187_abnormal_penis_morphology0.98870984
109MP0002086_abnormal_extraembryonic_tissu0.98488822
110MP0003705_abnormal_hypodermis_morpholog0.98286665
111MP0001545_abnormal_hematopoietic_system0.98258199
112MP0005397_hematopoietic_system_phenotyp0.98258199
113MP0002177_abnormal_outer_ear0.97247572
114MP0003635_abnormal_synaptic_transmissio0.96333806
115MP0002161_abnormal_fertility/fecundity0.95903443
116MP0002067_abnormal_sensory_capabilities0.95536119
117MP0003786_premature_aging0.92530208
118MP0001348_abnormal_lacrimal_gland0.92190632
119MP0002111_abnormal_tail_morphology0.92135884
120MP0006072_abnormal_retinal_apoptosis0.91828175
121MP0001984_abnormal_olfaction0.90453093
122MP0004145_abnormal_muscle_electrophysio0.89887011
123MP0003755_abnormal_palate_morphology0.89488990
124MP0001661_extended_life_span0.89177965
125MP0003121_genomic_imprinting0.88391309
126MP0008995_early_reproductive_senescence0.88028887
127MP0002064_seizures0.87855191
128MP0003077_abnormal_cell_cycle0.87832227
129MP0000678_abnormal_parathyroid_gland0.87585085
130MP0001286_abnormal_eye_development0.86313416
131MP0008961_abnormal_basal_metabolism0.84838972
132MP0008877_abnormal_DNA_methylation0.84669277
133MP0001186_pigmentation_phenotype0.84446019
134MP0009250_abnormal_appendicular_skeleto0.84032645
135MP0001440_abnormal_grooming_behavior0.83308948
136MP0001501_abnormal_sleep_pattern0.81721090
137MP0004133_heterotaxia0.81639415
138MP0005220_abnormal_exocrine_pancreas0.81217153
139MP0002734_abnormal_mechanical_nocicepti0.81193779
140MP0002063_abnormal_learning/memory/cond0.81115575
141MP0003942_abnormal_urinary_system0.80461733
142MP0010030_abnormal_orbit_morphology0.80006440
143MP0005083_abnormal_biliary_tract0.79955972
144MP0000537_abnormal_urethra_morphology0.79685176
145MP0009046_muscle_twitch0.79153545
146MP0000613_abnormal_salivary_gland0.78497103
147MP0002233_abnormal_nose_morphology0.78472621
148MP0003123_paternal_imprinting0.77116554
149MP0000681_abnormal_thyroid_gland0.76922806
150MP0005384_cellular_phenotype0.74361160
151MP0008007_abnormal_cellular_replicative0.73698270
152MP0009697_abnormal_copulation0.73661438
153MP0000490_abnormal_crypts_of0.73523444
154MP0003890_abnormal_embryonic-extraembry0.72841957
155MP0001119_abnormal_female_reproductive0.72217497
156MP0003567_abnormal_fetal_cardiomyocyte0.71184307
157MP0003861_abnormal_nervous_system0.70606219
158MP0002882_abnormal_neuron_morphology0.70347353
159MP0005253_abnormal_eye_physiology0.70307042
160MP0000383_abnormal_hair_follicle0.69178113
161MP0000462_abnormal_digestive_system0.68544120
162MP0001270_distended_abdomen0.67235510
163MP0004264_abnormal_extraembryonic_tissu0.66681044
164MP0003943_abnormal_hepatobiliary_system0.66654376
165MP0005621_abnormal_cell_physiology0.66212238
166MP0001849_ear_inflammation0.64075167
167MP0002089_abnormal_postnatal_growth/wei0.63718396
168MP0002098_abnormal_vibrissa_morphology0.62780033
169MP0002234_abnormal_pharynx_morphology0.62404393

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)3.82545399
2Birth length less than 3rd percentile (HP:0003561)3.66950208
3Chromosomal breakage induced by crosslinking agents (HP:0003221)3.60473228
4Abnormality of reticulocytes (HP:0004312)3.53525727
5Increased hepatocellular lipid droplets (HP:0006565)3.50907860
6Reticulocytosis (HP:0001923)3.46247892
7Abnormality of the renal collecting system (HP:0004742)3.26630062
8Chromsome breakage (HP:0040012)3.26257064
9Microvesicular hepatic steatosis (HP:0001414)3.19954008
10Cholecystitis (HP:0001082)3.15049871
11Abnormal gallbladder physiology (HP:0012438)3.15049871
12Duplicated collecting system (HP:0000081)3.14640310
13Increased nuchal translucency (HP:0010880)3.11326346
14Renal Fanconi syndrome (HP:0001994)3.04350330
1511 pairs of ribs (HP:0000878)2.92984735
16Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.92662356
17Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.76547538
18Facial hemangioma (HP:0000329)2.75933579
19Abnormality of the preputium (HP:0100587)2.73998684
20Breast hypoplasia (HP:0003187)2.67764499
21Septo-optic dysplasia (HP:0100842)2.66946512
22Lipid accumulation in hepatocytes (HP:0006561)2.66247783
23Mitochondrial inheritance (HP:0001427)2.64559779
24Abnormality of the heme biosynthetic pathway (HP:0010472)2.58944621
25Acute lymphatic leukemia (HP:0006721)2.57623294
26Duplication of thumb phalanx (HP:0009942)2.55609353
27Abnormality of DNA repair (HP:0003254)2.53852436
28Abnormality of secondary sexual hair (HP:0009888)2.53554641
29Abnormality of the axillary hair (HP:0100134)2.53554641
30Small intestinal stenosis (HP:0012848)2.49977937
31Duodenal stenosis (HP:0100867)2.49977937
32Abnormality of glycolysis (HP:0004366)2.48945463
33Acute necrotizing encephalopathy (HP:0006965)2.46678308
34Squamous cell carcinoma (HP:0002860)2.45204083
35Pallor (HP:0000980)2.45076237
36Abnormality of renal resorption (HP:0011038)2.43955637
37Macrocytic anemia (HP:0001972)2.43659425
38Exertional dyspnea (HP:0002875)2.43561459
39Ragged-red muscle fibers (HP:0003200)2.43242730
40Poikiloderma (HP:0001029)2.42856612
41Triphalangeal thumb (HP:0001199)2.42316821
42Testicular atrophy (HP:0000029)2.41266010
43Abnormality of cochlea (HP:0000375)2.38971806
44Abnormality of the carotid arteries (HP:0005344)2.37612182
45Hypoparathyroidism (HP:0000829)2.35368057
46Volvulus (HP:0002580)2.33858136
47Dynein arm defect of respiratory motile cilia (HP:0012255)2.33151038
48Absent/shortened dynein arms (HP:0200106)2.33151038
49Aplasia/Hypoplasia of the sacrum (HP:0008517)2.32618241
50Abnormal respiratory motile cilium morphology (HP:0005938)2.31894614
51Abnormal respiratory epithelium morphology (HP:0012253)2.31894614
52Medial flaring of the eyebrow (HP:0010747)2.31278392
53Nasolacrimal duct obstruction (HP:0000579)2.31030820
54Fair hair (HP:0002286)2.30865036
55Cholelithiasis (HP:0001081)2.30566353
56Progressive muscle weakness (HP:0003323)2.30551132
57Hyperthyroidism (HP:0000836)2.30090671
58Patellar aplasia (HP:0006443)2.30043577
59Aplasia/Hypoplasia of the patella (HP:0006498)2.28771860
60Ectopic kidney (HP:0000086)2.27654206
61True hermaphroditism (HP:0010459)2.27366334
62Abnormality of cells of the erythroid lineage (HP:0012130)2.27159283
63Meckel diverticulum (HP:0002245)2.25863719
64Aplasia/Hypoplasia of the uvula (HP:0010293)2.24423415
65Abnormal ciliary motility (HP:0012262)2.23881242
66Ureteral duplication (HP:0000073)2.20288516
67Myelodysplasia (HP:0002863)2.20080769
68Abnormality of chromosome stability (HP:0003220)2.20005753
69Cafe-au-lait spot (HP:0000957)2.18216501
70Absent septum pellucidum (HP:0001331)2.18106780
713-Methylglutaconic aciduria (HP:0003535)2.16727290
72Abnormality of the septum pellucidum (HP:0007375)2.16640030
73Insomnia (HP:0100785)2.15476144
74Abnormal number of incisors (HP:0011064)2.14535142
75Tubulointerstitial nephritis (HP:0001970)2.12931617
76Abnormality of the ileum (HP:0001549)2.12784190
77Nephrogenic diabetes insipidus (HP:0009806)2.10996478
78Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.10366584
79Focal motor seizures (HP:0011153)2.09978480
80Absent radius (HP:0003974)2.09922079
81Congenital sensorineural hearing impairment (HP:0008527)2.08991991
82Febrile seizures (HP:0002373)2.08347438
83Cupped ear (HP:0000378)2.08001281
84Increased CSF lactate (HP:0002490)2.07841569
85Proximal placement of thumb (HP:0009623)2.07172896
86Truncus arteriosus (HP:0001660)2.04537391
87Abnormal number of erythroid precursors (HP:0012131)2.04298843
88Premature skin wrinkling (HP:0100678)2.03896331
89Gait imbalance (HP:0002141)2.03335582
90Progressive external ophthalmoplegia (HP:0000590)2.03320933
91Pancreatic fibrosis (HP:0100732)2.02962790
92Progressive macrocephaly (HP:0004481)2.01947627
93Aplasia involving forearm bones (HP:0009822)2.01897113
94Absent forearm bone (HP:0003953)2.01897113
95Choanal atresia (HP:0000453)1.99073051
96Embryonal neoplasm (HP:0002898)1.99020850
97Congenital primary aphakia (HP:0007707)1.98454179
98Morphological abnormality of the inner ear (HP:0011390)1.98373083
99Abnormality of the nasolacrimal system (HP:0000614)1.98178012
100Embryonal renal neoplasm (HP:0011794)1.96911597
101Increased serum pyruvate (HP:0003542)1.96556208
102Homocystinuria (HP:0002156)1.96357446
103Abnormality of homocysteine metabolism (HP:0010919)1.96357446
104Atresia of the external auditory canal (HP:0000413)1.93995802
105Preaxial hand polydactyly (HP:0001177)1.93248441
106Congenital, generalized hypertrichosis (HP:0004540)1.93054868
107Parakeratosis (HP:0001036)1.92988196
108Optic disc pallor (HP:0000543)1.92893608
109Decreased central vision (HP:0007663)1.92297902
110Abnormality of the lacrimal duct (HP:0011481)1.92023496
111Abnormal lung lobation (HP:0002101)1.91781972
112Anomalous pulmonary venous return (HP:0010772)1.91738635
113Anencephaly (HP:0002323)1.90695352
114Overfolded helix (HP:0000396)1.90596458
115Morphological abnormality of the middle ear (HP:0008609)1.90589771
116Abnormal mitochondria in muscle tissue (HP:0008316)1.90406095
117Deviation of the thumb (HP:0009603)1.89991840
118Abnormal gallbladder morphology (HP:0012437)1.89643767
119Molar tooth sign on MRI (HP:0002419)1.89609054
120Abnormality of midbrain morphology (HP:0002418)1.89609054
121Sloping forehead (HP:0000340)1.87843618
122Male pseudohermaphroditism (HP:0000037)1.87318919
123Intestinal fistula (HP:0100819)1.87286575
124Partial duplication of thumb phalanx (HP:0009944)1.86766518
125Premature ovarian failure (HP:0008209)1.86159419
126Aplasia/Hypoplasia of the earlobes (HP:0009906)1.85643600
127Short thumb (HP:0009778)1.85631117
128Septate vagina (HP:0001153)1.85555923
129Abnormality of pyrimidine metabolism (HP:0004353)1.85466603
130Aplasia cutis congenita (HP:0001057)1.84601906
131White forelock (HP:0002211)1.84469474
132Abnormality of the duodenum (HP:0002246)1.84186860
133Xerostomia (HP:0000217)1.83788587
134Abnormality of the incisor (HP:0000676)1.83624239
135Broad distal phalanx of finger (HP:0009836)1.83621757
136Pancreatic cysts (HP:0001737)1.83399285
137Abnormal respiratory motile cilium physiology (HP:0012261)1.82858124
138Optic nerve hypoplasia (HP:0000609)1.82789138
139Horseshoe kidney (HP:0000085)1.82301536
140Nephroblastoma (Wilms tumor) (HP:0002667)1.81824221
141Supernumerary spleens (HP:0009799)1.81644044
142Impulsivity (HP:0100710)1.81402844
143Generalized hypopigmentation of hair (HP:0011358)1.80910309
144Abnormality of incisor morphology (HP:0011063)1.80274003
145Stomach cancer (HP:0012126)1.80246765
146Overlapping toe (HP:0001845)1.79911319
147Intestinal atresia (HP:0011100)1.79493422
148Aganglionic megacolon (HP:0002251)1.79278605
149Thin ribs (HP:0000883)1.77047254
150Hypoplasia of the capital femoral epiphysis (HP:0003090)1.76824055
151Nephronophthisis (HP:0000090)1.76815094
152Sparse lateral eyebrow (HP:0005338)1.76798489
153Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.76455802
154High anterior hairline (HP:0009890)1.76425148
155Missing ribs (HP:0000921)1.76119465
156Absent thumb (HP:0009777)1.76047323
157Abnormality of the calcaneus (HP:0008364)1.75631760
158Upper limb muscle weakness (HP:0003484)1.75354565
159Hyperacusis (HP:0010780)1.75112960
160Abnormality of the gallbladder (HP:0005264)1.73937947
161Short chin (HP:0000331)1.72860265
162Protruding tongue (HP:0010808)1.72523836
163Respiratory difficulties (HP:0002880)1.70888147
164Ileus (HP:0002595)1.70817098
165Selective tooth agenesis (HP:0001592)1.69541214
166Abnormality of the pulmonary veins (HP:0011718)1.69412296
167Anophthalmia (HP:0000528)1.69378637
168Increased intramyocellular lipid droplets (HP:0012240)1.69297000
169Obsessive-compulsive behavior (HP:0000722)1.68197641
170Medulloblastoma (HP:0002885)1.63357062
171Bowel incontinence (HP:0002607)1.62163518
172Abnormality of chromosome segregation (HP:0002916)1.62049824
173Osteomalacia (HP:0002749)1.60823046
174Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.60312670
175Absent epiphyses (HP:0010577)1.60312670

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK3.62930818
2ZAK3.36210022
3TRIB33.16869929
4CDK123.15934327
5EEF2K3.10873805
6STK163.01342415
7MKNK22.92973466
8MAP3K102.89442852
9SRPK12.86835209
10SMG12.83608954
11TLK12.56371922
12NEK22.24117244
13MKNK12.18513338
14BUB12.18242409
15VRK22.17434427
16TNIK2.17124668
17IRAK32.09685918
18EPHA42.01834275
19PNCK1.94282232
20ICK1.91276292
21VRK11.86918535
22EIF2AK21.75239884
23RPS6KB21.74310120
24TTK1.73479063
25PBK1.72364525
26FES1.65714635
27BRSK11.61603568
28NEK11.61057017
29IRAK41.57691951
30MAP2K71.51015467
31PDK21.49887004
32STK391.48322535
33TXK1.45773250
34MUSK1.44353182
35PKN11.42425622
36MAPK111.42229468
37CDK41.39323141
38CHEK11.36576961
39IRAK21.32748729
40PLK31.23854186
41NEK61.23308364
42FGR1.21981240
43BMPR1B1.21263711
44BMPR21.19580951
45MAPK131.18667724
46PLK21.16797821
47MAP3K81.15968099
48SCYL21.15011324
49YES11.14019834
50CDC71.13514893
51IRAK11.11945610
52GRK71.11460355
53CDK31.11035897
54PKN21.11032559
55SIK11.08660849
56NME11.05185377
57PLK11.04527725
58BCR1.02974113
59EIF2AK11.02222778
60CLK11.00981549
61MST1R1.00139386
62CDK20.99957413
63BRAF0.97913784
64MTOR0.97575782
65CHEK20.96894342
66CCNB10.96545899
67PLK40.93853095
68RIPK40.92209868
69TAF10.91612971
70STK40.90809400
71ERN10.89863199
72CAMK2B0.89199090
73DYRK1A0.89129859
74BRSK20.86160739
75NUAK10.85034132
76WEE10.83590935
77CDK80.82759717
78RAF10.82723954
79MARK10.82668535
80OXSR10.80240279
81AURKB0.78382378
82ADRBK20.75955671
83GRK50.75323734
84NME20.74516684
85ARAF0.74298172
86TEC0.73461618
87UHMK10.72793665
88DYRK20.72637372
89CDK11A0.72324111
90PIM20.72132612
91GRK10.71846538
92TAOK20.70440093
93STK30.70315597
94ATR0.68338332
95AKT20.68185555
96AURKA0.66907586
97MAP3K130.64575511
98CDK150.64285399
99TNK20.64225355
100CAMK2A0.63246710
101MET0.63217897
102BRD40.62165556
103CDK190.61997681
104CDK70.61260569
105WNK40.61186961
106CDK90.60912644
107ATM0.58629298
108AKT30.57735218
109MAPK150.57237443
110SIK20.57126625
111CDK180.56124484
112STK38L0.55793323
113RPS6KA50.55305681
114MST40.54625582
115NTRK20.53788032
116NTRK30.52684585
117BMX0.52640424
118MAPK140.50945311
119FLT30.49802320
120LYN0.49391158
121GSK3B0.49164529
122PRKDC0.48938809
123PRKCE0.48463808
124ADRBK10.48349560
125MAPKAPK50.47732705
126EIF2AK30.47583499
127PRPF4B0.47544124
128DYRK30.47377087
129PASK0.46081436
130CAMK2D0.45372558
131EPHA20.45094317
132MAP2K30.44901889
133CSNK2A20.44545758
134BLK0.44356123
135CAMK10.44283855
136CDK140.43939670
137KSR20.43443023
138PIM10.41550502
139PRKCQ0.41364699
140AKT10.41289762
141LATS20.41177118
142NLK0.40875091
143ILK0.40864077
144CSNK1A1L0.40776764
145PRKACA0.40050373
146TSSK60.39128986
147MAP3K40.39003655
148CDK60.38649121
149CSNK1G10.38478207
150CDK10.38153009
151CSNK1E0.37715421
152GRK60.37665125
153MAP3K60.37495885
154PRKCI0.37240839
155PIK3CA0.36768440
156CSNK2A10.36624912
157CSNK1G30.36302543
158MAP2K10.33250556
159PAK10.33244798
160MELK0.31995682

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.32970809
2Sulfur relay system_Homo sapiens_hsa041223.62592972
3RNA polymerase_Homo sapiens_hsa030203.03431894
4Fanconi anemia pathway_Homo sapiens_hsa034602.93728032
5Oxidative phosphorylation_Homo sapiens_hsa001902.77223440
6Homologous recombination_Homo sapiens_hsa034402.64535339
7Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.22953518
8Spliceosome_Homo sapiens_hsa030402.22080638
9Parkinsons disease_Homo sapiens_hsa050122.19347043
10Nicotine addiction_Homo sapiens_hsa050332.16899906
11Non-homologous end-joining_Homo sapiens_hsa034502.16654625
12Biosynthesis of amino acids_Homo sapiens_hsa012302.07424748
13Huntingtons disease_Homo sapiens_hsa050162.05448801
14Alzheimers disease_Homo sapiens_hsa050101.98216157
15Mismatch repair_Homo sapiens_hsa034301.89100601
16Basal transcription factors_Homo sapiens_hsa030221.80800346
17Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.78901557
18Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.76812524
19DNA replication_Homo sapiens_hsa030301.64807341
20Pyrimidine metabolism_Homo sapiens_hsa002401.64180142
21Phototransduction_Homo sapiens_hsa047441.64091195
22Cysteine and methionine metabolism_Homo sapiens_hsa002701.62860498
23Pentose phosphate pathway_Homo sapiens_hsa000301.61957557
24Protein export_Homo sapiens_hsa030601.59217259
25Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.53147514
26Carbon metabolism_Homo sapiens_hsa012001.46761016
27Pyruvate metabolism_Homo sapiens_hsa006201.45665534
28RNA degradation_Homo sapiens_hsa030181.44240410
29Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.39573053
30Nucleotide excision repair_Homo sapiens_hsa034201.38020685
31Serotonergic synapse_Homo sapiens_hsa047261.35463464
32Proteasome_Homo sapiens_hsa030501.34357426
33Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.33696861
34Cyanoamino acid metabolism_Homo sapiens_hsa004601.31078532
35Fructose and mannose metabolism_Homo sapiens_hsa000511.29781864
36Base excision repair_Homo sapiens_hsa034101.29656494
37Taste transduction_Homo sapiens_hsa047421.25401027
38Purine metabolism_Homo sapiens_hsa002301.21833490
39Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.21071839
40Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.15525847
41Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.14806482
422-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.09856272
43Lysine degradation_Homo sapiens_hsa003101.09751433
44Autoimmune thyroid disease_Homo sapiens_hsa053201.09548422
45Systemic lupus erythematosus_Homo sapiens_hsa053221.08465872
46Glutamatergic synapse_Homo sapiens_hsa047241.07512495
47Cell cycle_Homo sapiens_hsa041101.05407197
48Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.03905241
49Sphingolipid metabolism_Homo sapiens_hsa006001.03703671
50Cardiac muscle contraction_Homo sapiens_hsa042601.02429177
51Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.01857723
52RNA transport_Homo sapiens_hsa030131.01197125
53Central carbon metabolism in cancer_Homo sapiens_hsa052300.99460730
54Ether lipid metabolism_Homo sapiens_hsa005650.97616966
55Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.95080142
56Morphine addiction_Homo sapiens_hsa050320.92977742
57Axon guidance_Homo sapiens_hsa043600.91931677
58Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.91417360
59Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.87480196
60Arachidonic acid metabolism_Homo sapiens_hsa005900.86232986
61Bladder cancer_Homo sapiens_hsa052190.84255685
62p53 signaling pathway_Homo sapiens_hsa041150.83795709
63mRNA surveillance pathway_Homo sapiens_hsa030150.83703246
64Arginine biosynthesis_Homo sapiens_hsa002200.81655662
65Calcium signaling pathway_Homo sapiens_hsa040200.80874694
66Graft-versus-host disease_Homo sapiens_hsa053320.80871997
67Fatty acid elongation_Homo sapiens_hsa000620.80793383
68Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.80740456
69Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.77875990
70Long-term depression_Homo sapiens_hsa047300.77819554
71Primary immunodeficiency_Homo sapiens_hsa053400.77578649
72Basal cell carcinoma_Homo sapiens_hsa052170.75366470
73Thyroid cancer_Homo sapiens_hsa052160.74829954
74Folate biosynthesis_Homo sapiens_hsa007900.74537704
75Viral carcinogenesis_Homo sapiens_hsa052030.73458583
76Hematopoietic cell lineage_Homo sapiens_hsa046400.71585300
77Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.71113915
78Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.69767756
79African trypanosomiasis_Homo sapiens_hsa051430.68113460
80Alcoholism_Homo sapiens_hsa050340.67360890
81Non-small cell lung cancer_Homo sapiens_hsa052230.67114502
82Galactose metabolism_Homo sapiens_hsa000520.66110926
83Circadian entrainment_Homo sapiens_hsa047130.66031552
84Vitamin B6 metabolism_Homo sapiens_hsa007500.65169359
85Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.64643719
86Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.64438572
87N-Glycan biosynthesis_Homo sapiens_hsa005100.63645501
88MicroRNAs in cancer_Homo sapiens_hsa052060.63249570
89Amphetamine addiction_Homo sapiens_hsa050310.62262772
90Chronic myeloid leukemia_Homo sapiens_hsa052200.62218226
91Wnt signaling pathway_Homo sapiens_hsa043100.61365963
92Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.61132104
93Salivary secretion_Homo sapiens_hsa049700.58455407
94Intestinal immune network for IgA production_Homo sapiens_hsa046720.57405998
95Selenocompound metabolism_Homo sapiens_hsa004500.56889366
96Small cell lung cancer_Homo sapiens_hsa052220.56755720
97Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.56321965
98Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.55564180
99Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.55326485
100Long-term potentiation_Homo sapiens_hsa047200.55310470
101Thyroid hormone signaling pathway_Homo sapiens_hsa049190.53587984
102Allograft rejection_Homo sapiens_hsa053300.52928868
103One carbon pool by folate_Homo sapiens_hsa006700.52890025
104Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.52620461
105Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.52515269
106GABAergic synapse_Homo sapiens_hsa047270.52416319
107Hedgehog signaling pathway_Homo sapiens_hsa043400.51070672
108Epstein-Barr virus infection_Homo sapiens_hsa051690.50326761
109Longevity regulating pathway - mammal_Homo sapiens_hsa042110.49614143
110Transcriptional misregulation in cancer_Homo sapiens_hsa052020.49278989
111Arginine and proline metabolism_Homo sapiens_hsa003300.48687624
112Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.48538846
113Olfactory transduction_Homo sapiens_hsa047400.48200365
114HTLV-I infection_Homo sapiens_hsa051660.48135214
115Collecting duct acid secretion_Homo sapiens_hsa049660.47902677
116NF-kappa B signaling pathway_Homo sapiens_hsa040640.45951661
117Dopaminergic synapse_Homo sapiens_hsa047280.43316718
118Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.42840229
119Cholinergic synapse_Homo sapiens_hsa047250.42436895
120Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.42033423
121Rheumatoid arthritis_Homo sapiens_hsa053230.41861520
122Melanogenesis_Homo sapiens_hsa049160.41214516
123Asthma_Homo sapiens_hsa053100.38513035
124Linoleic acid metabolism_Homo sapiens_hsa005910.36749515
125Cocaine addiction_Homo sapiens_hsa050300.36209980
126Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.34975646
127Acute myeloid leukemia_Homo sapiens_hsa052210.34582037
128mTOR signaling pathway_Homo sapiens_hsa041500.33462135
129Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.33212609
130Pancreatic cancer_Homo sapiens_hsa052120.33101578
131Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.32333326
132Ovarian steroidogenesis_Homo sapiens_hsa049130.31329589
133Renin secretion_Homo sapiens_hsa049240.30959816
134Herpes simplex infection_Homo sapiens_hsa051680.30795272
135Oocyte meiosis_Homo sapiens_hsa041140.30711025
136SNARE interactions in vesicular transport_Homo sapiens_hsa041300.29528366
137Endometrial cancer_Homo sapiens_hsa052130.29400586
138Metabolic pathways_Homo sapiens_hsa011000.28482570
139NOD-like receptor signaling pathway_Homo sapiens_hsa046210.27708899
140Ras signaling pathway_Homo sapiens_hsa040140.27622568
141Insulin signaling pathway_Homo sapiens_hsa049100.26515677
142Vascular smooth muscle contraction_Homo sapiens_hsa042700.26327445
143Pancreatic secretion_Homo sapiens_hsa049720.26099809
144Other glycan degradation_Homo sapiens_hsa005110.25576251
145Colorectal cancer_Homo sapiens_hsa052100.25500236
146Oxytocin signaling pathway_Homo sapiens_hsa049210.25254358
147Steroid biosynthesis_Homo sapiens_hsa001000.24967622
148Gap junction_Homo sapiens_hsa045400.23825618
149Hippo signaling pathway_Homo sapiens_hsa043900.23359762
150AMPK signaling pathway_Homo sapiens_hsa041520.22644475
151Fatty acid metabolism_Homo sapiens_hsa012120.22220291
152Tyrosine metabolism_Homo sapiens_hsa003500.20815717
153Glycerophospholipid metabolism_Homo sapiens_hsa005640.19414198
154Thyroid hormone synthesis_Homo sapiens_hsa049180.19035453
155VEGF signaling pathway_Homo sapiens_hsa043700.18954576
156Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.18604967
157Phenylalanine metabolism_Homo sapiens_hsa003600.15984121
158Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.15901870
159Notch signaling pathway_Homo sapiens_hsa043300.13755957
160Glutathione metabolism_Homo sapiens_hsa004800.11910838

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