RBM42

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)6.14094388
2negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)4.84322917
3formation of translation preinitiation complex (GO:0001731)4.52641142
4COPI coating of Golgi vesicle (GO:0048205)4.48085891
5Golgi transport vesicle coating (GO:0048200)4.48085891
6protein maturation by protein folding (GO:0022417)4.40449615
7maturation of SSU-rRNA (GO:0030490)4.34512268
8regulation of mammary gland epithelial cell proliferation (GO:0033599)4.29180637
9viral transcription (GO:0019083)4.20768618
10ribosomal small subunit assembly (GO:0000028)4.14955605
11DNA strand elongation involved in DNA replication (GO:0006271)4.10536435
12translational termination (GO:0006415)4.08946070
13nucleobase biosynthetic process (GO:0046112)4.07767997
14ribosome assembly (GO:0042255)4.03684281
15purine nucleobase biosynthetic process (GO:0009113)3.97005853
16nuclear envelope reassembly (GO:0031468)3.96885268
17mitotic nuclear envelope reassembly (GO:0007084)3.96885268
18ribosome biogenesis (GO:0042254)3.93915488
19translational initiation (GO:0006413)3.90521163
20proline biosynthetic process (GO:0006561)3.88908154
21DNA strand elongation (GO:0022616)3.82365839
22translational elongation (GO:0006414)3.81700837
23GDP-mannose metabolic process (GO:0019673)3.74544691
24ribonucleoprotein complex biogenesis (GO:0022613)3.74219150
25DNA unwinding involved in DNA replication (GO:0006268)3.73591180
26ribosomal small subunit biogenesis (GO:0042274)3.72193533
27folic acid metabolic process (GO:0046655)3.71016304
28pentose-phosphate shunt (GO:0006098)3.71011391
29proteasome assembly (GO:0043248)3.69152876
30DNA replication initiation (GO:0006270)3.63471254
31ribosomal large subunit biogenesis (GO:0042273)3.62238910
32telomere maintenance via semi-conservative replication (GO:0032201)3.49524059
33protein retention in ER lumen (GO:0006621)3.49190149
34folic acid-containing compound biosynthetic process (GO:0009396)3.47747772
35nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.46391689
36DNA replication checkpoint (GO:0000076)3.44543888
37negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.42964132
38SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.39410618
39regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.35487818
40barbed-end actin filament capping (GO:0051016)3.35136542
41anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.33478259
42spliceosomal tri-snRNP complex assembly (GO:0000244)3.32784096
43viral life cycle (GO:0019058)3.31342024
44NIK/NF-kappaB signaling (GO:0038061)3.30282603
45glucose catabolic process (GO:0006007)3.29492324
46rRNA processing (GO:0006364)3.29012268
47regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.28790592
48maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.28004190
49negative regulation of cell size (GO:0045792)3.27416295
50protein targeting to ER (GO:0045047)3.27062375
51positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.26638197
52retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.25552378
53mitotic nuclear envelope disassembly (GO:0007077)3.25106981
54cotranslational protein targeting to membrane (GO:0006613)3.24265323
55spliceosomal snRNP assembly (GO:0000387)3.23371540
56cellular protein complex disassembly (GO:0043624)3.21398683
57IMP biosynthetic process (GO:0006188)3.20981373
58pentose metabolic process (GO:0019321)3.20934632
59negative regulation of release of cytochrome c from mitochondria (GO:0090201)3.20322789
60protein localization to kinetochore (GO:0034501)3.19064884
61rRNA metabolic process (GO:0016072)3.17162846
62nucleobase-containing small molecule interconversion (GO:0015949)3.15305046
63negative regulation of ligase activity (GO:0051352)3.14290913
64negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.14290913
65apoptotic process involved in morphogenesis (GO:0060561)3.13450972
66mitotic metaphase plate congression (GO:0007080)3.13286052
67histone arginine methylation (GO:0034969)3.12808325
68DNA replication-dependent nucleosome organization (GO:0034723)3.12446216
69DNA replication-dependent nucleosome assembly (GO:0006335)3.12446216
70UV protection (GO:0009650)3.11882939
71NADPH regeneration (GO:0006740)3.11841428
72protein localization to endoplasmic reticulum (GO:0070972)3.11302501
73negative regulation of erythrocyte differentiation (GO:0045647)3.09298690
74mitotic chromosome condensation (GO:0007076)3.08722803
75deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.08195547
76Arp2/3 complex-mediated actin nucleation (GO:0034314)3.08041377
77peptidyl-arginine N-methylation (GO:0035246)3.07062820
78peptidyl-arginine methylation (GO:0018216)3.07062820
79establishment of protein localization to endoplasmic reticulum (GO:0072599)3.06858406
80positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling3.02390113
81nuclear envelope disassembly (GO:0051081)3.01358338
82membrane disassembly (GO:0030397)3.01358338
83protein complex disassembly (GO:0043241)3.00551705
843-UTR-mediated mRNA stabilization (GO:0070935)3.00028352
85negative regulation of translational initiation (GO:0045947)2.99161462
86pinocytosis (GO:0006907)2.97703254
87positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.93727266
88negative regulation of B cell apoptotic process (GO:0002903)2.92802712
89protein localization to chromosome, centromeric region (GO:0071459)2.91194989
90pseudouridine synthesis (GO:0001522)2.90072118
91telomere maintenance via recombination (GO:0000722)2.89863223
92translation (GO:0006412)2.89319066
93mitotic G1 DNA damage checkpoint (GO:0031571)2.85805710
94regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.84584177
95macromolecular complex disassembly (GO:0032984)2.83329166
96negative regulation of DNA-templated transcription, elongation (GO:0032785)2.83017839
97endoplasmic reticulum calcium ion homeostasis (GO:0032469)2.79899135
98IMP metabolic process (GO:0046040)2.79487522
99positive regulation of ligase activity (GO:0051351)2.79132659
100telomere maintenance via telomere lengthening (GO:0010833)2.78825972
101regulation of translation in response to stress (GO:0043555)2.76526692
102rRNA modification (GO:0000154)2.76406027
103protein localization to endosome (GO:0036010)2.74059597
104ncRNA 3-end processing (GO:0043628)2.73860032
105regulation of translational termination (GO:0006449)2.72439356
106DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.72157549
107positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)2.71723912
108intracellular estrogen receptor signaling pathway (GO:0030520)2.71444317
109regulation of spindle organization (GO:0090224)2.70548899
110pyrimidine-containing compound salvage (GO:0008655)2.69504552
111pyrimidine nucleoside salvage (GO:0043097)2.69504552
112negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.68882083
113signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.68512109
114signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.68512109
115signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.68512109
116regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2.68312425
117signal transduction involved in DNA integrity checkpoint (GO:0072401)2.68213553
118signal transduction involved in DNA damage checkpoint (GO:0072422)2.68213553
119guanosine-containing compound biosynthetic process (GO:1901070)2.68047684
120intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.67366313
121signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.67366313
122nuclear-transcribed mRNA catabolic process (GO:0000956)2.67048674
1232-deoxyribonucleotide biosynthetic process (GO:0009265)2.64979536
124deoxyribose phosphate biosynthetic process (GO:0046385)2.64979536
125regulation of ubiquitin-protein transferase activity (GO:0051438)2.64885595
126regulation of superoxide anion generation (GO:0032928)2.64859188
127negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.64697793
128nucleotide salvage (GO:0043173)2.63248566
129mitotic recombination (GO:0006312)2.63041143
130signal transduction involved in cell cycle checkpoint (GO:0072395)2.62838384
131negative regulation of chromosome segregation (GO:0051985)2.62329389
132peptidyl-arginine omega-N-methylation (GO:0035247)2.62011728
133nuclear envelope organization (GO:0006998)2.61549066
134cell cycle G1/S phase transition (GO:0044843)2.61432943
135G1/S transition of mitotic cell cycle (GO:0000082)2.61432943
136regulation of cellular amino acid metabolic process (GO:0006521)2.60801729
137transcription elongation from RNA polymerase III promoter (GO:0006385)2.60609354
138termination of RNA polymerase III transcription (GO:0006386)2.60609354
139regulation of apoptotic process involved in morphogenesis (GO:1902337)2.59782631
140protein insertion into membrane (GO:0051205)2.59732944
141chaperone mediated protein folding requiring cofactor (GO:0051085)2.59162363
142antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.58747107
143cellular component biogenesis (GO:0044085)2.57828637
144mitotic spindle assembly checkpoint (GO:0007094)2.55642048
145RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.55275517
146mRNA splicing, via spliceosome (GO:0000398)2.55275517
147RNA splicing, via transesterification reactions (GO:0000375)2.54708898
148RNA catabolic process (GO:0006401)2.53958241
149negative regulation of mitotic sister chromatid segregation (GO:0033048)2.53943748
150mitochondrial fusion (GO:0008053)2.52170708
151heterochromatin organization (GO:0070828)2.52111292
152modulation by symbiont of host cellular process (GO:0044068)2.51461191
153virion assembly (GO:0019068)2.50592549
154regulation of early endosome to late endosome transport (GO:2000641)2.49705294
155modulation by virus of host process (GO:0019054)2.48871289
156establishment of viral latency (GO:0019043)2.47861484
157amyloid precursor protein catabolic process (GO:0042987)2.47395503
158pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.47321156
159pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.46777803
160rRNA transcription (GO:0009303)2.43597281
161pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.42618086
162regulation of mitochondrial translation (GO:0070129)2.41730315
163positive regulation of Cdc42 GTPase activity (GO:0043089)2.41605729
164NADH metabolic process (GO:0006734)2.41208140
165establishment of integrated proviral latency (GO:0075713)2.39454316
166negative regulation of necroptotic process (GO:0060546)2.38823418
167proline metabolic process (GO:0006560)2.38348085
168glucose 6-phosphate metabolic process (GO:0051156)2.36003061
169UTP biosynthetic process (GO:0006228)2.35701521
170regulation of translational fidelity (GO:0006450)2.33810598
171mature B cell differentiation involved in immune response (GO:0002313)2.33459876
172pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.32563880
173pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.31830302
174regulation of mitochondrial membrane potential (GO:0051881)2.30571958
175activation of MAPKKK activity (GO:0000185)2.30442920
176regulation of defense response to virus by virus (GO:0050690)2.29578598
177negative regulation of myeloid cell apoptotic process (GO:0033033)2.29021928
178activation of Rac GTPase activity (GO:0032863)2.26641969
179response to peptidoglycan (GO:0032494)2.26560438
180viral mRNA export from host cell nucleus (GO:0046784)2.26082144
181viral protein processing (GO:0019082)2.24002312
182negative regulation of mRNA processing (GO:0050686)2.23686833
183regulation of necrotic cell death (GO:0010939)2.23106351
184positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.22603586
185negative regulation of viral release from host cell (GO:1902187)2.19488332

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.07510706
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.89542201
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.54972194
4FOXM1_23109430_ChIP-Seq_U2OS_Human2.63930639
5MYC_18358816_ChIP-ChIP_MESCs_Mouse2.52727350
6MYC_19079543_ChIP-ChIP_MESCs_Mouse2.52380623
7* ETS1_20019798_ChIP-Seq_JURKAT_Human2.52276593
8* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.47274563
9MYC_22102868_ChIP-Seq_BL_Human2.34706946
10GABP_17652178_ChIP-ChIP_JURKAT_Human2.28281079
11MYC_19030024_ChIP-ChIP_MESCs_Mouse2.27781265
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.19661459
13* XRN2_22483619_ChIP-Seq_HELA_Human2.19204221
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.16490648
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.15752014
16PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.07845046
17NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.07175471
18E2F4_17652178_ChIP-ChIP_JURKAT_Human2.06760029
19KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.99121907
20RARG_19884340_ChIP-ChIP_MEFs_Mouse1.92717989
21NELFA_20434984_ChIP-Seq_ESCs_Mouse1.89304428
22HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.86464963
23EGR1_19374776_ChIP-ChIP_THP-1_Human1.84372348
24VDR_21846776_ChIP-Seq_THP-1_Human1.83631079
25* VDR_23849224_ChIP-Seq_CD4+_Human1.79501703
26SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.78650907
27GABP_19822575_ChIP-Seq_HepG2_Human1.77407895
28E2F1_18555785_ChIP-Seq_MESCs_Mouse1.74815567
29RACK7_27058665_Chip-Seq_MCF-7_Human1.74484669
30ELF1_17652178_ChIP-ChIP_JURKAT_Human1.73685286
31TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.69259425
32THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.69143575
33DCP1A_22483619_ChIP-Seq_HELA_Human1.67554328
34NANOG_18555785_ChIP-Seq_MESCs_Mouse1.64453948
35CIITA_25753668_ChIP-Seq_RAJI_Human1.62981905
36STAT3_1855785_ChIP-Seq_MESCs_Mouse1.62759365
37FOXP3_21729870_ChIP-Seq_TREG_Human1.59705235
38MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.57829109
39SRY_22984422_ChIP-ChIP_TESTIS_Rat1.54126711
40KDM2B_26808549_Chip-Seq_SUP-B15_Human1.52055470
41P68_20966046_ChIP-Seq_HELA_Human1.51186395
42TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.50974158
43ZFX_18555785_ChIP-Seq_MESCs_Mouse1.49518349
44* TTF2_22483619_ChIP-Seq_HELA_Human1.48785017
45ZNF263_19887448_ChIP-Seq_K562_Human1.48748484
46THAP11_20581084_ChIP-Seq_MESCs_Mouse1.48586436
47TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.47553479
48AR_21909140_ChIP-Seq_LNCAP_Human1.47404913
49YY1_21170310_ChIP-Seq_MESCs_Mouse1.45242283
50POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.44995198
51CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.44520818
52KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.43260178
53SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.41676852
54KLF4_18555785_ChIP-Seq_MESCs_Mouse1.40567241
55FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.39548912
56CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.39162527
57ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.38889244
58E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.38441742
59KDM2B_26808549_Chip-Seq_DND41_Human1.38241976
60DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.37796626
61SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.34892680
62SA1_27219007_Chip-Seq_ERYTHROID_Human1.33204458
63MYCN_18555785_ChIP-Seq_MESCs_Mouse1.32337421
64ELK3_25401928_ChIP-Seq_HUVEC_Human1.31066424
65POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.31038891
66KDM5A_27292631_Chip-Seq_BREAST_Human1.30231091
67CTCF_27219007_Chip-Seq_ERYTHROID_Human1.28594510
68VDR_24763502_ChIP-Seq_THP-1_Human1.27033415
69MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.25816927
70SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.24057541
71ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.23562265
72E2F1_21310950_ChIP-Seq_MCF-7_Human1.22480856
73UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.21077031
74HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.16678499
75BCOR_27268052_Chip-Seq_Bcells_Human1.16578633
76CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.16447762
77NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.16286312
78SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.16189897
79SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.15067636
80CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.12886384
81NOTCH1_21737748_ChIP-Seq_TLL_Human1.12374983
82CTCF_18555785_ChIP-Seq_MESCs_Mouse1.12082905
83PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.11674204
84CTCF_26484167_Chip-Seq_Bcells_Mouse1.11465036
85NCOR1_26117541_ChIP-Seq_K562_Human1.10720259
86* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.10525932
87MAF_26560356_Chip-Seq_TH1_Human1.10202902
88ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.09840693
89TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.09818916
90TFEB_21752829_ChIP-Seq_HELA_Human1.09777358
91ERG_20887958_ChIP-Seq_HPC-7_Mouse1.08727916
92NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.08153692
93MAF_26560356_Chip-Seq_TH2_Human1.07705784
94OCT4_18692474_ChIP-Seq_MEFs_Mouse1.06918320
95TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.06572256
96NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.06214193
97SPI1_23547873_ChIP-Seq_NB4_Human1.06069960
98* UTX_26944678_Chip-Seq_JUKART_Human1.05527492
99KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.03795525
100ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.03752115
101PU.1_20513432_ChIP-Seq_Bcells_Mouse1.03683699
102PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.03654930
103LXR_22292898_ChIP-Seq_THP-1_Human1.03584071
104RUNX1_22412390_ChIP-Seq_EML_Mouse1.03206561
105FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.03117587
106PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.03049320
107SRF_21415370_ChIP-Seq_HL-1_Mouse1.02228217
108SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.01858169
109RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.01704275
110RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.01518083
111TCF7_22412390_ChIP-Seq_EML_Mouse1.01313526
112KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.01301680
113* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.01281073
114KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.00792807
115BRD4_27068464_Chip-Seq_AML-cells_Mouse1.00075345
116CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.00001615
117YY1_22570637_ChIP-Seq_MALME-3M_Human0.99909607
118KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.99768067
119SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.99495996
120HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.99317637
121SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.99200127
122BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.98855435
123SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.98578616
124HOXB4_20404135_ChIP-ChIP_EML_Mouse0.98372208
125TET1_21451524_ChIP-Seq_MESCs_Mouse0.97806165
126* ATF3_27146783_Chip-Seq_COLON_Human0.96928014
127GATA1_22383799_ChIP-Seq_G1ME_Mouse0.96842560
128SOX2_18692474_ChIP-Seq_MEFs_Mouse0.95634346
129BCL6_27268052_Chip-Seq_Bcells_Human0.95485482
130ELF1_20517297_ChIP-Seq_JURKAT_Human0.95052916
131TP63_17297297_ChIP-ChIP_HaCaT_Human0.94961077

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.16663568
2MP0004957_abnormal_blastocyst_morpholog3.74617828
3MP0003111_abnormal_nucleus_morphology3.56329748
4MP0005058_abnormal_lysosome_morphology3.42015615
5MP0005451_abnormal_body_composition3.31892313
6MP0003077_abnormal_cell_cycle2.98488358
7MP0010094_abnormal_chromosome_stability2.75403363
8MP0002877_abnormal_melanocyte_morpholog2.75177202
9MP0010352_gastrointestinal_tract_polyps2.47363391
10MP0004185_abnormal_adipocyte_glucose2.43024462
11MP0002396_abnormal_hematopoietic_system2.42089810
12MP0009333_abnormal_splenocyte_physiolog2.22382684
13MP0009840_abnormal_foam_cell2.18897699
14MP0001730_embryonic_growth_arrest2.12920278
15MP0008007_abnormal_cellular_replicative2.07682831
16MP0008932_abnormal_embryonic_tissue2.02057345
17MP0000685_abnormal_immune_system2.01457248
18MP0003315_abnormal_perineum_morphology2.00299922
19MP0003763_abnormal_thymus_physiology1.97817630
20MP0000490_abnormal_crypts_of1.97798978
21MP0008058_abnormal_DNA_repair1.97350863
22MP0004858_abnormal_nervous_system1.87302143
23MP0008057_abnormal_DNA_replication1.86939194
24MP0000678_abnormal_parathyroid_gland1.86401250
25MP0005623_abnormal_meninges_morphology1.84053023
26MP0000350_abnormal_cell_proliferation1.77768984
27MP0001545_abnormal_hematopoietic_system1.67818290
28MP0005397_hematopoietic_system_phenotyp1.67818290
29MP0003453_abnormal_keratinocyte_physiol1.53573278
30MP0004233_abnormal_muscle_weight1.50273795
31MP0002398_abnormal_bone_marrow1.49397286
32MP0003786_premature_aging1.49239097
33MP0003123_paternal_imprinting1.47758104
34MP0009278_abnormal_bone_marrow1.47200551
35MP0002080_prenatal_lethality1.45870108
36MP0010234_abnormal_vibrissa_follicle1.45482531
37MP0005380_embryogenesis_phenotype1.44578820
38MP0001672_abnormal_embryogenesis/_devel1.44578820
39MP0008438_abnormal_cutaneous_collagen1.44438061
40MP0003436_decreased_susceptibility_to1.44320758
41MP0002249_abnormal_larynx_morphology1.44130841
42MP0002722_abnormal_immune_system1.43483996
43MP0001697_abnormal_embryo_size1.43324368
44MP0003718_maternal_effect1.43247516
45MP0002019_abnormal_tumor_incidence1.43240800
46MP0000313_abnormal_cell_death1.42913310
47MP0005666_abnormal_adipose_tissue1.42650192
48MP0000537_abnormal_urethra_morphology1.42317575
49MP0002796_impaired_skin_barrier1.41378446
50MP0000003_abnormal_adipose_tissue1.41230037
51MP0002653_abnormal_ependyma_morphology1.39892828
52MP0000689_abnormal_spleen_morphology1.39246452
53MP0004808_abnormal_hematopoietic_stem1.37323958
54MP0010307_abnormal_tumor_latency1.34374757
55MP0000703_abnormal_thymus_morphology1.33765730
56MP0005375_adipose_tissue_phenotype1.33044438
57MP0003984_embryonic_growth_retardation1.32078673
58MP0002088_abnormal_embryonic_growth/wei1.30821560
59MP0003806_abnormal_nucleotide_metabolis1.30177265
60MP0005076_abnormal_cell_differentiation1.28735107
61MP0002429_abnormal_blood_cell1.26231692
62MP0003075_altered_response_to1.24739233
63MP0000681_abnormal_thyroid_gland1.24517834
64MP0003705_abnormal_hypodermis_morpholog1.23657076
65MP0001835_abnormal_antigen_presentation1.21751341
66MP0000716_abnormal_immune_system1.20915394
67MP0003878_abnormal_ear_physiology1.20511610
68MP0005377_hearing/vestibular/ear_phenot1.20511610
69MP0000343_altered_response_to1.20218804
70MP0005023_abnormal_wound_healing1.19573682
71MP0002085_abnormal_embryonic_tissue1.18391349
72MP0001800_abnormal_humoral_immune1.15517580
73MP0010030_abnormal_orbit_morphology1.15429358
74MP0002405_respiratory_system_inflammati1.15422721
75MP0000733_abnormal_muscle_development1.15322679
76MP0008260_abnormal_autophagy1.14978937
77MP0002132_abnormal_respiratory_system1.14931092
78MP0002086_abnormal_extraembryonic_tissu1.14536673
79MP0000858_altered_metastatic_potential1.11312578
80MP0001819_abnormal_immune_cell1.10056974
81MP0002452_abnormal_antigen_presenting1.09766002
82MP0001849_ear_inflammation1.09679049
83MP0002420_abnormal_adaptive_immunity1.09529661
84MP0003303_peritoneal_inflammation1.08907177
85MP0002723_abnormal_immune_serum1.06949708
86MP0001853_heart_inflammation1.06852179
87MP0000751_myopathy1.05525871
88MP0002084_abnormal_developmental_patter1.05360107
89MP0003191_abnormal_cellular_cholesterol1.04801679
90MP0000358_abnormal_cell_content/1.04636250
91MP0004510_myositis1.03722377
92MP0005671_abnormal_response_to1.03668404
93MP0005670_abnormal_white_adipose1.01524013
94MP0001661_extended_life_span1.00536541
95MP0000747_muscle_weakness0.99891839
96MP0005330_cardiomyopathy0.99383002
97MP0005025_abnormal_response_to0.99132089
98MP0003300_gastrointestinal_ulcer0.98933151
99MP0001873_stomach_inflammation0.98337409
100MP0009785_altered_susceptibility_to0.98328649
101MP0003329_amyloid_beta_deposits0.98300610
102MP0005075_abnormal_melanosome_morpholog0.98126509
103MP0009053_abnormal_anal_canal0.96641262
104MP0005000_abnormal_immune_tolerance0.96176970
105MP0003566_abnormal_cell_adhesion0.96159815
106MP0005257_abnormal_intraocular_pressure0.95806979
107MP0004197_abnormal_fetal_growth/weight/0.95694997
108MP0003279_aneurysm0.95564518
109MP0004947_skin_inflammation0.95298425
110MP0003119_abnormal_digestive_system0.94948354
111MP0003221_abnormal_cardiomyocyte_apopto0.94704238
112MP0010155_abnormal_intestine_physiology0.94622239
113MP0000759_abnormal_skeletal_muscle0.93791139
114MP0002160_abnormal_reproductive_system0.93335086
115MP0000477_abnormal_intestine_morphology0.92093443
116MP0004272_abnormal_basement_membrane0.92025644
117MP0003866_abnormal_defecation0.90870335
118MP0001346_abnormal_lacrimal_gland0.90707279
119MP0003172_abnormal_lysosome_physiology0.90483839
120MP0001533_abnormal_skeleton_physiology0.90128901
121MP0000465_gastrointestinal_hemorrhage0.89937956
122MP0009672_abnormal_birth_weight0.89114910
123MP0002148_abnormal_hypersensitivity_rea0.88940619
124MP0000750_abnormal_muscle_regeneration0.86727965
125MP0002419_abnormal_innate_immunity0.86545167
126MP0002060_abnormal_skin_morphology0.86196417
127MP0003186_abnormal_redox_activity0.83654507
128MP0001727_abnormal_embryo_implantation0.83331795
129MP0003091_abnormal_cell_migration0.81424256
130MP0001542_abnormal_bone_strength0.80088533
131MP0006036_abnormal_mitochondrial_physio0.79854323
132MP0001216_abnormal_epidermal_layer0.79730252
133MP0005621_abnormal_cell_physiology0.79344999
134MP0008877_abnormal_DNA_methylation0.78741834
135MP0009379_abnormal_foot_pigmentation0.78160362
136MP0009931_abnormal_skin_appearance0.77396615
137MP0005384_cellular_phenotype0.76384141
138MP0005390_skeleton_phenotype0.76050735
139MP0002166_altered_tumor_susceptibility0.74453472
140MP0001845_abnormal_inflammatory_respons0.74101580
141MP0005387_immune_system_phenotype0.74037009
142MP0001790_abnormal_immune_system0.74037009
143MP0003567_abnormal_fetal_cardiomyocyte0.71632737
144MP0000598_abnormal_liver_morphology0.70912770
145MP0005501_abnormal_skin_physiology0.69922223
146MP0001145_abnormal_male_reproductive0.69588986
147MP0005464_abnormal_platelet_physiology0.65337592

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)4.04648634
2Abnormal number of erythroid precursors (HP:0012131)3.97240659
3Carpal bone hypoplasia (HP:0001498)3.91698501
4Breast hypoplasia (HP:0003187)3.65482920
5Ragged-red muscle fibers (HP:0003200)3.47944437
6Oral leukoplakia (HP:0002745)3.42836764
7Achilles tendon contracture (HP:0001771)3.41139423
8Cerebral hypomyelination (HP:0006808)3.36633638
9Multiple enchondromatosis (HP:0005701)3.35419714
10Reticulocytopenia (HP:0001896)3.34272243
11Birth length less than 3rd percentile (HP:0003561)3.32743042
12Distal lower limb amyotrophy (HP:0008944)3.21253316
13Progressive muscle weakness (HP:0003323)3.17272253
14Rough bone trabeculation (HP:0100670)3.12609016
15Microretrognathia (HP:0000308)3.07433464
16Trismus (HP:0000211)3.07019344
17Hyperacusis (HP:0010780)3.06486664
18Premature ovarian failure (HP:0008209)3.04875550
19Degeneration of anterior horn cells (HP:0002398)3.02800220
20Abnormality of the anterior horn cell (HP:0006802)3.02800220
21Abnormality of the Achilles tendon (HP:0005109)3.00004688
22Abnormality of liposaccharide metabolism (HP:0010968)2.98735281
23Abnormality of glycosphingolipid metabolism (HP:0004343)2.98735281
24Abnormality of glycolipid metabolism (HP:0010969)2.98735281
25Broad distal phalanx of finger (HP:0009836)2.93969699
26Selective tooth agenesis (HP:0001592)2.92477590
27Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.90423477
28Centrally nucleated skeletal muscle fibers (HP:0003687)2.87067022
29Patellar aplasia (HP:0006443)2.83982002
30Distal lower limb muscle weakness (HP:0009053)2.82391506
31Macrocytic anemia (HP:0001972)2.81850591
32Abnormal gallbladder physiology (HP:0012438)2.81233629
33Cholecystitis (HP:0001082)2.81233629
34Premature rupture of membranes (HP:0001788)2.80184097
35Aplasia/Hypoplasia of the patella (HP:0006498)2.77695578
36Polycythemia (HP:0001901)2.69326034
37Elevated erythrocyte sedimentation rate (HP:0003565)2.68783212
38Hypertensive crisis (HP:0100735)2.63735585
39Tongue fasciculations (HP:0001308)2.62170944
40Pustule (HP:0200039)2.58230939
41Petechiae (HP:0000967)2.58047088
42Pallor (HP:0000980)2.55803528
43Thrombocytosis (HP:0001894)2.54568824
44Increased connective tissue (HP:0009025)2.54276616
45Secondary amenorrhea (HP:0000869)2.53198610
46Muscle fibrillation (HP:0010546)2.50753918
47Neoplasm of the pancreas (HP:0002894)2.47397073
48Ulnar bowing (HP:0003031)2.45937558
49IgM deficiency (HP:0002850)2.44032792
50Aplastic anemia (HP:0001915)2.41738580
51Cellulitis (HP:0100658)2.34430772
52Chronic otitis media (HP:0000389)2.34347833
53Breech presentation (HP:0001623)2.33738845
54Personality changes (HP:0000751)2.28188237
55Abnormality of the nasal mucosa (HP:0000433)2.28069177
56Distal upper limb amyotrophy (HP:0007149)2.27999567
57Upper limb amyotrophy (HP:0009129)2.27999567
58Increased cerebral lipofuscin (HP:0011813)2.26768678
59Short nail (HP:0001799)2.26148740
60Abnormality of T cell physiology (HP:0011840)2.26077912
61Axonal loss (HP:0003447)2.25298379
62Nasal polyposis (HP:0100582)2.24835105
63Overlapping toe (HP:0001845)2.22586309
64Atrophy/Degeneration involving motor neurons (HP:0007373)2.22182382
65Stridor (HP:0010307)2.19961224
66Myopathic facies (HP:0002058)2.19589973
67Generalized amyotrophy (HP:0003700)2.19110843
68Entropion (HP:0000621)2.15762295
69Testicular atrophy (HP:0000029)2.14958330
70Prolonged neonatal jaundice (HP:0006579)2.14470380
71Facial hemangioma (HP:0000329)2.13281183
72Single umbilical artery (HP:0001195)2.11094864
73Abnormality of the fetal cardiovascular system (HP:0010948)2.11094864
74Abnormal umbilical cord blood vessels (HP:0011403)2.11094864
75Long palpebral fissure (HP:0000637)2.09177614
76Abnormal trabecular bone morphology (HP:0100671)2.08950015
77Aplasia/Hypoplasia of the sacrum (HP:0008517)2.06886808
78Microvesicular hepatic steatosis (HP:0001414)2.05752613
79Hepatosplenomegaly (HP:0001433)2.02714071
80Nonimmune hydrops fetalis (HP:0001790)2.01991918
81Increased neuronal autofluorescent lipopigment (HP:0002074)2.00045184
82Abnormality of T cells (HP:0002843)1.99006452
83Dysostosis multiplex (HP:0000943)1.97584648
84Obstructive lung disease (HP:0006536)1.96870491
85Chronic obstructive pulmonary disease (HP:0006510)1.96870491
86Recurrent bronchitis (HP:0002837)1.96375601
87Abnormality of the umbilical cord (HP:0010881)1.96328234
88Insomnia (HP:0100785)1.95084328
89Poor head control (HP:0002421)1.94526491
90CNS hypomyelination (HP:0003429)1.94279474
91Upper motor neuron abnormality (HP:0002127)1.93954706
92Absent thumb (HP:0009777)1.93914943
93Loss of speech (HP:0002371)1.91452049
94Hyperparathyroidism (HP:0000843)1.91449581
95Lower limb amyotrophy (HP:0007210)1.90815846
96Elbow flexion contracture (HP:0002987)1.90165635
97Basal cell carcinoma (HP:0002671)1.89239887
98Cleft eyelid (HP:0000625)1.88933053
99Pelvic girdle muscle weakness (HP:0003749)1.88154585
100Truncus arteriosus (HP:0001660)1.87887723
101Abnormality of the motor neurons (HP:0002450)1.87453943
102Abnormal neuron morphology (HP:0012757)1.87453943
103Decreased activity of mitochondrial respiratory chain (HP:0008972)1.86266872
104Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.86266872
105Slender long bone (HP:0003100)1.85907597
106Cellular immunodeficiency (HP:0005374)1.85630659
107Sparse eyelashes (HP:0000653)1.85325180
108Poikiloderma (HP:0001029)1.84961329
109Colon cancer (HP:0003003)1.84928748
110Spinal rigidity (HP:0003306)1.84416864
111Abnormality of skeletal muscle fiber size (HP:0012084)1.84054245
112Premature graying of hair (HP:0002216)1.83750797
113Protrusio acetabuli (HP:0003179)1.81504556
114Absent radius (HP:0003974)1.80564582
115Abnormality of the tricuspid valve (HP:0001702)1.80480658
116Calcaneovalgus deformity (HP:0001848)1.79352267
117Hypokinesia (HP:0002375)1.78971834
118Increased muscle lipid content (HP:0009058)1.78691030
119Broad face (HP:0000283)1.78088421
120Gastrointestinal dysmotility (HP:0002579)1.76974954
121Hypertriglyceridemia (HP:0002155)1.76442987
122Prominent nose (HP:0000448)1.76437540
123Reticulocytosis (HP:0001923)1.76051940
124Bulbar palsy (HP:0001283)1.75631883
125Acanthosis nigricans (HP:0000956)1.75345935
126Hemorrhage of the eye (HP:0011885)1.73992600
127Death in infancy (HP:0001522)1.73646594
128Premature skin wrinkling (HP:0100678)1.73604939
129Fasciculations (HP:0002380)1.73544302
130Back pain (HP:0003418)1.72487574
131Increased variability in muscle fiber diameter (HP:0003557)1.72399532
132Increased serum ferritin (HP:0003281)1.71742252
133Purpura (HP:0000979)1.71706654
134Reduced subcutaneous adipose tissue (HP:0003758)1.71448633
135Abnormality of macrophages (HP:0004311)1.70535312
136Combined immunodeficiency (HP:0005387)1.70314369
137Abnormality of the distal phalanges of the toes (HP:0010182)1.68922537
138Cholelithiasis (HP:0001081)1.68767941
139Orthostatic hypotension (HP:0001278)1.68531290
140Interstitial pulmonary disease (HP:0006530)1.68493867
141Hyperthyroidism (HP:0000836)1.68369711
142Glossoptosis (HP:0000162)1.68352700
143Nuclear cataract (HP:0100018)1.67769977
144Ankle contracture (HP:0006466)1.67054294
145Progressive neurologic deterioration (HP:0002344)1.66725980
146Absent forearm bone (HP:0003953)1.66614524
147Aplasia involving forearm bones (HP:0009822)1.66614524
148Aplasia/hypoplasia of the humerus (HP:0006507)1.66379983
149Ependymoma (HP:0002888)1.66342666
150Muscle fiber atrophy (HP:0100295)1.66324220
151Fragile skin (HP:0001030)1.65191567
152Lymphoma (HP:0002665)1.65044055
153Difficulty climbing stairs (HP:0003551)1.64857184
154Vertebral compression fractures (HP:0002953)1.64679970
155Abnormality of the thoracic spine (HP:0100711)1.63515133
156Abnormality of the alveolar ridges (HP:0006477)1.62958064
157Hypoplasia of the capital femoral epiphysis (HP:0003090)1.62782137
158Abnormality of the calcaneus (HP:0008364)1.61427107
159Deformed tarsal bones (HP:0008119)1.61401441
160Proximal placement of thumb (HP:0009623)1.60597443
161Abnormality of reticulocytes (HP:0004312)1.60410440
162Impulsivity (HP:0100710)1.60296032
163Seborrheic dermatitis (HP:0001051)1.59414186
164Recurrent abscess formation (HP:0002722)1.58972669
165Joint stiffness (HP:0001387)1.58933794
166Polygenic inheritance (HP:0010982)1.58519347
167Abnormalities of placenta or umbilical cord (HP:0001194)1.58278685
168Abnormal delayed hypersensitivity skin test (HP:0002963)1.58077043
169Atelectasis (HP:0100750)1.57999044
170Growth hormone excess (HP:0000845)1.57845926
171Broad alveolar ridges (HP:0000187)1.57689135
172Eczematoid dermatitis (HP:0000976)1.57157527
173Cerebral aneurysm (HP:0004944)1.56506465
174Biconcave vertebral bodies (HP:0004586)1.56377731
175Recurrent fungal infections (HP:0002841)1.56013477
176Tracheoesophageal fistula (HP:0002575)1.54473933
177Panhypogammaglobulinemia (HP:0003139)1.54409914
178Sparse lateral eyebrow (HP:0005338)1.54022569
179Abnormality of subcutaneous fat tissue (HP:0001001)1.53363383

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.53802687
2SMG13.44979381
3WEE13.04560938
4TESK22.86051873
5NME22.74214224
6NEK22.55180256
7VRK22.50884125
8TRIB32.49404691
9MAP4K12.41597747
10PIM22.26484449
11PRPF4B2.22672827
12EIF2AK12.17294520
13KDR2.16203840
14EEF2K2.11541203
15MAP3K102.09150782
16DYRK32.07424225
17TBK12.03991672
18EPHA22.02553455
19SIK12.01477598
20ERN11.88394260
21MAP3K111.88281012
22CDC71.74083949
23STK101.71631414
24STK161.65073801
25MAPKAPK31.64246897
26RPS6KA41.56445689
27TSSK61.53693423
28MAP3K81.53152649
29ZAP701.49015780
30GRK61.46267311
31PLK41.45928306
32TAOK11.45842825
33RPS6KB21.45703634
34LIMK11.42095347
35PAK41.39945339
36CDK71.36466018
37PLK11.34567324
38ACVR1B1.31551521
39TTK1.31546313
40ARAF1.28362096
41TLK11.27924993
42BLK1.26822551
43PKN21.25168361
44LRRK21.21876750
45TTN1.20064150
46CDK41.17864261
47TGFBR11.13967771
48AURKA1.09086591
49MAP2K21.07140215
50SCYL21.03519191
51TESK11.03483279
52ABL21.02585096
53CDK81.01408369
54AURKB1.00532213
55PIM10.94078739
56MAP2K30.92844214
57IKBKB0.92827750
58BCKDK0.92204407
59BRSK20.91681091
60PASK0.90176335
61FLT30.88605000
62IKBKE0.88047806
63BRAF0.86376896
64PAK10.85541388
65SRPK10.85336594
66BRSK10.84863031
67NEK10.81467020
68ATR0.80696855
69EIF2AK30.80681338
70MST1R0.79473750
71PRKCI0.78935788
72MAP3K10.78251034
73TAOK20.77993498
74VRK10.77428241
75LMTK20.76463254
76MAP3K30.76005196
77CHEK20.74532025
78TYK20.74241076
79DAPK10.73824121
80FGFR40.71935287
81PTK60.69179445
82CDK90.67789257
83MOS0.67610679
84JAK30.65747177
85RAF10.65679707
86IRAK20.64200038
87PRKD20.64016861
88MAP3K130.63287130
89LATS20.63059248
90PRKD30.62183263
91PTK20.58270402
92ALK0.57868710
93BTK0.57526455
94NLK0.57419562
95EPHB10.57003654
96ILK0.56857355
97CDK120.56670530
98BMX0.54134397
99TGFBR20.53201535
100DYRK20.53011777
101* CHEK10.49244731
102SIK30.48456991
103ICK0.47943842
104RPS6KL10.47017366
105RPS6KC10.47017366
106RPS6KA50.46937221
107CDK20.46514709
108CDC42BPA0.45912507
109PDPK10.45330113
110CDK11A0.43175222
111RPS6KA20.42909706
112PBK0.42830788
113EPHB20.42505460
114KSR20.41163465
115MTOR0.40868176
116MAPKAPK20.40435801
117PRKG20.38799689
118CHUK0.38759404
119MAPK110.38433753
120HIPK20.37932733
121KIT0.37675881
122PDGFRA0.37466603
123PAK20.37280045
124MAP3K140.36152599
125DAPK30.35915956
126AKT20.35871314
127CDK150.35222358
128RPS6KA10.33964954
129IRAK40.33381650
130CDK140.33017678
131CSNK2A20.32576520
132CCNB10.32178973
133IRAK30.31963774
134CSNK2A10.31545791
135STK40.30945117
136CSF1R0.30716938
137MARK20.30177263
138RIPK10.27636055
139PLK30.27278920

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.30888485
2Ribosome_Homo sapiens_hsa030103.65254723
3Proteasome_Homo sapiens_hsa030503.54087673
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.16191626
5Mismatch repair_Homo sapiens_hsa034303.08143116
6RNA polymerase_Homo sapiens_hsa030203.06510003
7Spliceosome_Homo sapiens_hsa030403.00455905
8Base excision repair_Homo sapiens_hsa034102.85574062
9RNA transport_Homo sapiens_hsa030132.78479359
10Cell cycle_Homo sapiens_hsa041102.26749163
11Pyrimidine metabolism_Homo sapiens_hsa002402.24265537
12Nucleotide excision repair_Homo sapiens_hsa034202.12605637
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.97000979
14Homologous recombination_Homo sapiens_hsa034401.94194933
15Folate biosynthesis_Homo sapiens_hsa007901.91458801
16Sulfur relay system_Homo sapiens_hsa041221.89868601
17p53 signaling pathway_Homo sapiens_hsa041151.84541962
18Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.83713385
19One carbon pool by folate_Homo sapiens_hsa006701.79478182
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.66395345
21Pentose phosphate pathway_Homo sapiens_hsa000301.58316629
22Vitamin B6 metabolism_Homo sapiens_hsa007501.49797399
23Epstein-Barr virus infection_Homo sapiens_hsa051691.43170650
24Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.39227292
25Antigen processing and presentation_Homo sapiens_hsa046121.37856628
26Prion diseases_Homo sapiens_hsa050201.35204218
27Vibrio cholerae infection_Homo sapiens_hsa051101.30693748
28Lysosome_Homo sapiens_hsa041421.23904103
29Primary immunodeficiency_Homo sapiens_hsa053401.23894582
30Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.19259265
31Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.15924101
32Herpes simplex infection_Homo sapiens_hsa051681.15641840
33Basal transcription factors_Homo sapiens_hsa030221.15467922
34Salmonella infection_Homo sapiens_hsa051321.13996909
35mRNA surveillance pathway_Homo sapiens_hsa030151.10050675
36Shigellosis_Homo sapiens_hsa051311.08963422
37RNA degradation_Homo sapiens_hsa030181.08362197
38Purine metabolism_Homo sapiens_hsa002301.05127605
39Viral carcinogenesis_Homo sapiens_hsa052031.02999140
40Biosynthesis of amino acids_Homo sapiens_hsa012301.00998002
41Drug metabolism - other enzymes_Homo sapiens_hsa009830.99537914
42Non-small cell lung cancer_Homo sapiens_hsa052230.96132802
43Toll-like receptor signaling pathway_Homo sapiens_hsa046200.96013461
44Cysteine and methionine metabolism_Homo sapiens_hsa002700.93139305
45Apoptosis_Homo sapiens_hsa042100.92136734
46Phenylalanine metabolism_Homo sapiens_hsa003600.91563194
47Legionellosis_Homo sapiens_hsa051340.91254465
48Fanconi anemia pathway_Homo sapiens_hsa034600.91166345
49Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.89087238
50HTLV-I infection_Homo sapiens_hsa051660.85668315
51Selenocompound metabolism_Homo sapiens_hsa004500.82399522
52RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.82050350
53Measles_Homo sapiens_hsa051620.80456166
54Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.79296536
55Fructose and mannose metabolism_Homo sapiens_hsa000510.77092188
56Osteoclast differentiation_Homo sapiens_hsa043800.76933376
57Acute myeloid leukemia_Homo sapiens_hsa052210.74758583
58Non-homologous end-joining_Homo sapiens_hsa034500.74413985
59Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.74006200
60Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.73553356
61Cyanoamino acid metabolism_Homo sapiens_hsa004600.71147787
62Other glycan degradation_Homo sapiens_hsa005110.70924942
63Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.69857886
64Thyroid cancer_Homo sapiens_hsa052160.69773370
65NF-kappa B signaling pathway_Homo sapiens_hsa040640.69716657
66Fatty acid elongation_Homo sapiens_hsa000620.69366017
67Endocytosis_Homo sapiens_hsa041440.68688368
68Chronic myeloid leukemia_Homo sapiens_hsa052200.66473811
69Galactose metabolism_Homo sapiens_hsa000520.65855637
70Notch signaling pathway_Homo sapiens_hsa043300.65218996
71Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.64619590
72Hepatitis B_Homo sapiens_hsa051610.64332671
73Bladder cancer_Homo sapiens_hsa052190.64149123
74Regulation of autophagy_Homo sapiens_hsa041400.63985282
75Systemic lupus erythematosus_Homo sapiens_hsa053220.62328712
76Leishmaniasis_Homo sapiens_hsa051400.60920900
77Small cell lung cancer_Homo sapiens_hsa052220.60860008
78Oocyte meiosis_Homo sapiens_hsa041140.60684583
79Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.59204572
80Neurotrophin signaling pathway_Homo sapiens_hsa047220.59035836
812-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.58442030
82Hepatitis C_Homo sapiens_hsa051600.58325418
83Tuberculosis_Homo sapiens_hsa051520.57150855
84TNF signaling pathway_Homo sapiens_hsa046680.56838790
85Carbon metabolism_Homo sapiens_hsa012000.53804947
86B cell receptor signaling pathway_Homo sapiens_hsa046620.53176155
87Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.53007970
88Alcoholism_Homo sapiens_hsa050340.52751615
89Adipocytokine signaling pathway_Homo sapiens_hsa049200.52071266
90Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.52021950
91Influenza A_Homo sapiens_hsa051640.50507420
92Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.50274278
93Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.50161579
94Intestinal immune network for IgA production_Homo sapiens_hsa046720.49567427
95Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.49155911
96Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.48038117
97Phagosome_Homo sapiens_hsa041450.46682529
98Insulin signaling pathway_Homo sapiens_hsa049100.45000191
99AMPK signaling pathway_Homo sapiens_hsa041520.44344178
100Transcriptional misregulation in cancer_Homo sapiens_hsa052020.44185221
101Colorectal cancer_Homo sapiens_hsa052100.43911791
102Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.42186623
103Glioma_Homo sapiens_hsa052140.42052993
104Huntingtons disease_Homo sapiens_hsa050160.41897551
105Viral myocarditis_Homo sapiens_hsa054160.41139865
106Parkinsons disease_Homo sapiens_hsa050120.40544241
107N-Glycan biosynthesis_Homo sapiens_hsa005100.40234082
108T cell receptor signaling pathway_Homo sapiens_hsa046600.39745060
109Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.39031350
110Sulfur metabolism_Homo sapiens_hsa009200.37980154
111Jak-STAT signaling pathway_Homo sapiens_hsa046300.37947597
112Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.36973988
113VEGF signaling pathway_Homo sapiens_hsa043700.36746410
114Pancreatic cancer_Homo sapiens_hsa052120.35308768
115Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.35049838
116MicroRNAs in cancer_Homo sapiens_hsa052060.34951762
117Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.34101183
118Glycosaminoglycan degradation_Homo sapiens_hsa005310.33571280
119Glutathione metabolism_Homo sapiens_hsa004800.32498259
120Leukocyte transendothelial migration_Homo sapiens_hsa046700.32467661
121Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.32411847
122Glycerophospholipid metabolism_Homo sapiens_hsa005640.30967659
123HIF-1 signaling pathway_Homo sapiens_hsa040660.30112511
124Central carbon metabolism in cancer_Homo sapiens_hsa052300.27414858
125Pertussis_Homo sapiens_hsa051330.26822331
126Toxoplasmosis_Homo sapiens_hsa051450.26138240
127mTOR signaling pathway_Homo sapiens_hsa041500.25505496
128Hippo signaling pathway_Homo sapiens_hsa043900.24747862
129Hematopoietic cell lineage_Homo sapiens_hsa046400.24619058
130Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.24457840
131Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.24213827
132Arginine and proline metabolism_Homo sapiens_hsa003300.24159053

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