RASSF4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The function of this gene has not yet been determined but may involve a role in tumor suppression. Alternative splicing of this gene results in several transcript variants; however, most of the variants have not been fully described. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1modulation by organism of immune response of other organism involved in symbiotic interaction (GO:006.77395621
2modulation by organism of defense response of other organism involved in symbiotic interaction (GO:06.77395621
3positive regulation by organism of defense response of other organism involved in symbiotic interact6.77395621
4modulation by symbiont of host immune response (GO:0052553)6.77395621
5positive regulation by symbiont of host defense response (GO:0052509)6.77395621
6modulation by symbiont of host defense response (GO:0052031)6.77395621
7neutrophil activation involved in immune response (GO:0002283)5.69729064
8antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.58889805
9response to peptidoglycan (GO:0032494)5.45724425
10macrophage activation involved in immune response (GO:0002281)5.18287595
11positive regulation of interferon-alpha production (GO:0032727)4.96615393
12regulation of interferon-beta biosynthetic process (GO:0045357)4.79064254
13regulation of interferon-alpha production (GO:0032647)4.69508149
14response to host immune response (GO:0052572)4.53973959
15response to immune response of other organism involved in symbiotic interaction (GO:0052564)4.53973959
16respiratory burst (GO:0045730)4.50230394
17immunoglobulin mediated immune response (GO:0016064)4.48511225
18granulocyte activation (GO:0036230)4.32627350
19response to muramyl dipeptide (GO:0032495)4.26548140
20lipopolysaccharide-mediated signaling pathway (GO:0031663)4.21185398
21microglial cell activation (GO:0001774)4.18565528
22positive regulation of cellular amide metabolic process (GO:0034250)4.16423087
23neutrophil activation (GO:0042119)4.15857441
24positive regulation of interleukin-8 biosynthetic process (GO:0045416)4.13663825
25hydrogen peroxide biosynthetic process (GO:0050665)4.13312216
26natural killer cell mediated immunity (GO:0002228)4.09910194
27natural killer cell mediated cytotoxicity (GO:0042267)4.09910194
28positive regulation of chemokine biosynthetic process (GO:0045080)4.01618105
29response to host (GO:0075136)4.00854165
30response to host defenses (GO:0052200)4.00854165
31response to defenses of other organism involved in symbiotic interaction (GO:0052173)4.00854165
32positive regulation of gamma-delta T cell activation (GO:0046645)3.93323442
33positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.81322999
34myeloid cell activation involved in immune response (GO:0002275)3.77701249
35reactive oxygen species biosynthetic process (GO:1903409)3.75570202
36positive regulation of interferon-beta production (GO:0032728)3.74416249
37positive regulation of antigen processing and presentation (GO:0002579)3.74297718
38type I interferon signaling pathway (GO:0060337)3.73389941
39cellular response to type I interferon (GO:0071357)3.73389941
40superoxide anion generation (GO:0042554)3.70824891
41response to type I interferon (GO:0034340)3.70473978
42macrophage activation (GO:0042116)3.66614056
43regulation of dendritic cell antigen processing and presentation (GO:0002604)3.64332537
44positive regulation of mast cell activation involved in immune response (GO:0033008)3.54886724
45positive regulation of mast cell degranulation (GO:0043306)3.54886724
46I-kappaB phosphorylation (GO:0007252)3.49887487
47positive regulation of heat generation (GO:0031652)3.49455168
48detection of molecule of bacterial origin (GO:0032490)3.47576674
49positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.46827442
50interferon-gamma-mediated signaling pathway (GO:0060333)3.44322274
51negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.43351457
52negative regulation of cell killing (GO:0031342)3.43351457
53defense response to protozoan (GO:0042832)3.43082562
54negative regulation of interleukin-17 production (GO:0032700)3.40964389
55positive regulation of interleukin-12 production (GO:0032735)3.40311292
56detection of other organism (GO:0098543)3.40123558
57regulation of chemokine biosynthetic process (GO:0045073)3.39920991
58NIK/NF-kappaB signaling (GO:0038061)3.39916292
59glycosphingolipid catabolic process (GO:0046479)3.39810928
60positive regulation of mast cell activation (GO:0033005)3.33640260
61T-helper 1 type immune response (GO:0042088)3.33520751
62leukocyte mediated cytotoxicity (GO:0001909)3.32005652
63antigen processing and presentation of endogenous antigen (GO:0019883)3.28878332
64production of molecular mediator involved in inflammatory response (GO:0002532)3.28684394
65regulation of mononuclear cell migration (GO:0071675)3.27676145
66positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)3.27000833
67B cell mediated immunity (GO:0019724)3.26895726
68regulation of mast cell degranulation (GO:0043304)3.26333665
69regulation of macrophage chemotaxis (GO:0010758)3.24949211
70regulation of interleukin-12 biosynthetic process (GO:0045075)3.24878328
71cellular response to thyroid hormone stimulus (GO:0097067)3.23455316
72neutrophil mediated immunity (GO:0002446)3.23353469
73regulation of T-helper 1 cell differentiation (GO:0045625)3.22277213
74regulation of fever generation (GO:0031620)3.21044651
75detection of external biotic stimulus (GO:0098581)3.20268529
76detection of bacterium (GO:0016045)3.19633369
77amino sugar catabolic process (GO:0046348)3.15578716
78cellular response to interferon-beta (GO:0035458)3.13712667
79regulation of antigen processing and presentation (GO:0002577)3.12515337
80regulation of syncytium formation by plasma membrane fusion (GO:0060142)3.10713054
81positive regulation of type 2 immune response (GO:0002830)3.10628327
82negative regulation of interleukin-12 production (GO:0032695)3.09261857
83germinal center formation (GO:0002467)3.07157723
84positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.06409925
85regulation of B cell receptor signaling pathway (GO:0050855)3.06135281
86cellular extravasation (GO:0045123)3.05133439
87glycolipid catabolic process (GO:0019377)3.04970042
88regulation of mast cell activation involved in immune response (GO:0033006)3.03098927
89regulation of interleukin-8 biosynthetic process (GO:0045414)3.00745568
90oligosaccharide catabolic process (GO:0009313)3.00439043
91regulation of interferon-gamma biosynthetic process (GO:0045072)3.00386828
92antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.00132473
93antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.00132473
94regulation of myeloid leukocyte mediated immunity (GO:0002886)2.99733515
95positive regulation of toll-like receptor signaling pathway (GO:0034123)2.99520193
96positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.98889953
97positive regulation of B cell differentiation (GO:0045579)2.97867649
98response to interferon-alpha (GO:0035455)2.96262796
99myeloid dendritic cell differentiation (GO:0043011)2.96171126
100myeloid leukocyte activation (GO:0002274)2.94667874
101positive regulation of chemokine production (GO:0032722)2.94565292
102cellular response to zinc ion (GO:0071294)2.94474993
103adenosine receptor signaling pathway (GO:0001973)2.93188290
104negative regulation of myeloid cell apoptotic process (GO:0033033)2.93138503
105regulation of interleukin-17 production (GO:0032660)2.92810426
106regulation of interleukin-12 production (GO:0032655)2.92609270
107lymphocyte chemotaxis (GO:0048247)2.90419903
108response to protozoan (GO:0001562)2.89409363
109positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.89378873
110regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.89117754
111positive regulation of leukocyte degranulation (GO:0043302)2.88667536
112regulation of mast cell activation (GO:0033003)2.88064353
113negative regulation of viral genome replication (GO:0045071)2.87557399
114regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.87447490
115positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.86633550
116cytokine secretion (GO:0050663)2.86171264
117regulation of hypersensitivity (GO:0002883)2.83158956
118detection of biotic stimulus (GO:0009595)2.82153542
119negative regulation of cytokine production involved in immune response (GO:0002719)2.75283175
120mannose metabolic process (GO:0006013)2.73224095
121regulation of gamma-delta T cell activation (GO:0046643)2.71292989
122ceramide catabolic process (GO:0046514)2.70201282
123regulation of leukocyte degranulation (GO:0043300)2.70140160
124negative regulation of erythrocyte differentiation (GO:0045647)2.68935654
125regulation of T-helper 2 cell differentiation (GO:0045628)2.67706660
126positive regulation of macrophage cytokine production (GO:0060907)2.60914976
127myeloid dendritic cell activation (GO:0001773)2.59951286
128cellular response to interferon-gamma (GO:0071346)2.59358683
129positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.59203772
130negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.59014869
131regulation of T cell tolerance induction (GO:0002664)2.58182405
132regulation of cholesterol storage (GO:0010885)2.54576646
133response to thyroid hormone (GO:0097066)2.49836288
134dendritic cell differentiation (GO:0097028)2.49770386
135barbed-end actin filament capping (GO:0051016)2.48936199
136regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.48523175
137response to interferon-gamma (GO:0034341)2.48231586
138regulation of type 2 immune response (GO:0002828)2.47243417
139negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.42973282
140positive regulation of cholesterol efflux (GO:0010875)2.41186082
141regulation of macrophage cytokine production (GO:0010935)2.40759338
142positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.39950399
143regulation of cytokine secretion involved in immune response (GO:0002739)2.39930053
144peptide catabolic process (GO:0043171)2.36999657
145virion attachment to host cell (GO:0019062)2.36748747
146adhesion of symbiont to host cell (GO:0044650)2.36748747

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_21731497_ChIP-ChIP_J774_Mouse7.49249302
2IRF8_22096565_ChIP-ChIP_GC-B_Human7.40349468
3BP1_19119308_ChIP-ChIP_Hs578T_Human6.07670869
4* IRF8_27001747_Chip-Seq_BMDM_Mouse4.78062368
5IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.44154214
6SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse4.40002515
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.32015317
8NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.90479046
9Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.85877829
10MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.38198552
11FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.29824615
12RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human3.05075174
13MYB_21317192_ChIP-Seq_ERMYB_Mouse3.03811904
14STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.92315856
15SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.82391482
16STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.71303059
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.60522294
18* STAT4_19710469_ChIP-ChIP_TH1__Mouse2.40610176
19NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.17890791
20SPI1_23547873_ChIP-Seq_NB4_Human2.17249792
21BRD4_27068464_Chip-Seq_AML-cells_Mouse2.16683785
22NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.14637143
23PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse2.11444294
24STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.91607964
25SPI1_23127762_ChIP-Seq_K562_Human1.85658714
26PU_27001747_Chip-Seq_BMDM_Mouse1.83475360
27VDR_24763502_ChIP-Seq_THP-1_Human1.80594253
28VDR_24787735_ChIP-Seq_THP-1_Human1.78510197
29* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.76814682
30LXR_22292898_ChIP-Seq_THP-1_Human1.76520908
31PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.74929209
32SCL_19346495_ChIP-Seq_HPC-7_Human1.70308044
33GATA1_22025678_ChIP-Seq_K562_Human1.68662224
34CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.66618662
35* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.62375736
36MYB_26560356_Chip-Seq_TH2_Human1.62116969
37ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.62029432
38RUNX_20019798_ChIP-Seq_JUKART_Human1.60408197
39MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.58918780
40VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.58817719
41RUNX1_22412390_ChIP-Seq_EML_Mouse1.57202323
42FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.49255427
43RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.48316558
44* MAF_26560356_Chip-Seq_TH1_Human1.46922737
45ESR2_21235772_ChIP-Seq_MCF-7_Human1.42379505
46THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.40461418
47MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.37885625
48MYB_26560356_Chip-Seq_TH1_Human1.37413629
49CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.37173015
50VDR_21846776_ChIP-Seq_THP-1_Human1.35085198
51CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.33617402
52FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.29861261
53ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.28189849
54RARG_19884340_ChIP-ChIP_MEFs_Mouse1.27011741
55RXR_22158963_ChIP-Seq_LIVER_Mouse1.26321119
56SMAD_19615063_ChIP-ChIP_OVARY_Human1.26097491
57NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.25984394
58PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.24946905
59PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.24131184
60LXR_22158963_ChIP-Seq_LIVER_Mouse1.22109443
61SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.20138049
62GATA3_26560356_Chip-Seq_TH2_Human1.20056796
63* KDM2B_26808549_Chip-Seq_DND41_Human1.17236462
64SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.16418080
65GATA2_21666600_ChIP-Seq_HMVEC_Human1.15436067
66E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.14270205
67* GATA3_27048872_Chip-Seq_THYMUS_Human1.13813275
68PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.12530051
69DROSHA_22980978_ChIP-Seq_HELA_Human1.11844324
70FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.11515178
71LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.11246143
72PPARA_22158963_ChIP-Seq_LIVER_Mouse1.10634843
73KDM2B_26808549_Chip-Seq_K562_Human1.08228921
74CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.04025414
75GATA2_22383799_ChIP-Seq_G1ME_Mouse1.02680582
76DNAJC2_21179169_ChIP-ChIP_NT2_Human0.98583979
77BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.98005726
78TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.97558052
79KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.95237041
80* TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.95226809
81TP63_17297297_ChIP-ChIP_HaCaT_Human0.94560434
82UTX_26944678_Chip-Seq_JUKART_Human0.93699061
83LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.92791050
84TRIM28_21343339_ChIP-Seq_HEK293_Human0.90346661
85CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.90327842
86TBX20_22080862_ChIP-Seq_HEART_Mouse0.89674724
87TBX20_22328084_ChIP-Seq_HEART_Mouse0.89674724
88SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.87681194
89* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.87577333
90IKZF1_21737484_ChIP-ChIP_HCT116_Human0.85995239
91GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.85013144
92* NFIB_24661679_ChIP-Seq_LUNG_Mouse0.84620165
93TCF7_22412390_ChIP-Seq_EML_Mouse0.84308029
94TFEB_21752829_ChIP-Seq_HELA_Human0.82715712
95SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82562979
96GATA1_19941827_ChIP-Seq_MEL_Mouse0.82372925
97BCL6_27268052_Chip-Seq_Bcells_Human0.82139615
98CLOCK_20551151_ChIP-Seq_293T_Human0.80905547
99SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.79364847
100EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.79016238
101BCOR_27268052_Chip-Seq_Bcells_Human0.77955136
102* NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.77628786
103NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.76789997
104NRF2_20460467_ChIP-Seq_MEFs_Mouse0.76789997
105GATA1_22383799_ChIP-Seq_G1ME_Mouse0.76061605
106MAF_26560356_Chip-Seq_TH2_Human0.74792493
107ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.73632385
108ELK3_25401928_ChIP-Seq_HUVEC_Human0.73367951
109GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71610361
110GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.71085590
111EGR1_19032775_ChIP-ChIP_M12_Human0.69800032
112SOX2_20726797_ChIP-Seq_SW620_Human0.69553946
113SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.69534073
114CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.69364544
115GATA2_19941826_ChIP-Seq_K562_Human0.68100183
116* CDX2_19796622_ChIP-Seq_MESCs_Mouse0.67151707
117CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.66767700
118TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.66261819
119SMRT_27268052_Chip-Seq_Bcells_Human0.65526144
120KDM2B_26808549_Chip-Seq_SUP-B15_Human0.63823341
121JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.61763074
122JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.61183256
123CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.60897971
124SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.60607387
125SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.60607387
126GATA1_19941826_ChIP-Seq_K562_Human0.60574532
127GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.60363645
128SPI1_20517297_ChIP-Seq_HL60_Human0.59992442
129PU.1_20513432_ChIP-Seq_Bcells_Mouse0.59672521
130CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.56555321
131KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.55641865

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.85471981
2MP0003436_decreased_susceptibility_to3.84259834
3MP0009785_altered_susceptibility_to3.77278122
4MP0003303_peritoneal_inflammation3.61899053
5MP0002148_abnormal_hypersensitivity_rea3.55560336
6MP0002419_abnormal_innate_immunity3.37192272
7MP0006082_CNS_inflammation3.30042841
8MP0005000_abnormal_immune_tolerance3.21635072
9MP0005058_abnormal_lysosome_morphology3.20115929
10MP0005025_abnormal_response_to3.03743218
11MP0005387_immune_system_phenotype2.98769666
12MP0001790_abnormal_immune_system2.98769666
13MP0000685_abnormal_immune_system2.87781760
14MP0002452_abnormal_antigen_presenting2.76111495
15MP0004510_myositis2.73405965
16MP0000569_abnormal_digit_pigmentation2.69681447
17MP0003724_increased_susceptibility_to2.65529281
18MP0001800_abnormal_humoral_immune2.59268567
19MP0002723_abnormal_immune_serum2.53707442
20MP0005671_abnormal_response_to2.47392080
21MP0002139_abnormal_hepatobiliary_system2.44933442
22MP0001819_abnormal_immune_cell2.26733492
23MP0003172_abnormal_lysosome_physiology2.23664648
24MP0002420_abnormal_adaptive_immunity2.22030812
25MP0005464_abnormal_platelet_physiology2.14158425
26MP0001533_abnormal_skeleton_physiology2.01338954
27MP0004947_skin_inflammation1.99961612
28MP0002405_respiratory_system_inflammati1.91975477
29MP0001853_heart_inflammation1.91668097
30MP0009764_decreased_sensitivity_to1.89171095
31MP0003329_amyloid_beta_deposits1.87438633
32MP0001845_abnormal_inflammatory_respons1.87224743
33MP0009278_abnormal_bone_marrow1.79192538
34MP0002006_tumorigenesis1.75610735
35MP0008469_abnormal_protein_level1.71444157
36MP0003075_altered_response_to1.71272660
37MP0003448_altered_tumor_morphology1.71088607
38MP0005310_abnormal_salivary_gland1.62905857
39MP0010155_abnormal_intestine_physiology1.60051790
40MP0000716_abnormal_immune_system1.58533789
41MP0002998_abnormal_bone_remodeling1.53753309
42MP0000343_altered_response_to1.53651569
43MP0003183_abnormal_peptide_metabolism1.48469475
44MP0002398_abnormal_bone_marrow1.44662890
45MP0000604_amyloidosis1.43395761
46MP0005451_abnormal_body_composition1.40297572
47MP0009840_abnormal_foam_cell1.36888247
48MP0001545_abnormal_hematopoietic_system1.35085080
49MP0005397_hematopoietic_system_phenotyp1.35085080
50MP0003191_abnormal_cellular_cholesterol1.34550389
51MP0002166_altered_tumor_susceptibility1.33977900
52MP0009333_abnormal_splenocyte_physiolog1.33882796
53MP0005174_abnormal_tail_pigmentation1.32594994
54MP0005166_decreased_susceptibility_to1.28305477
55MP0000858_altered_metastatic_potential1.25396940
56MP0002429_abnormal_blood_cell1.23617659
57MP0000689_abnormal_spleen_morphology1.23416449
58MP0003690_abnormal_glial_cell1.23194332
59MP0005167_abnormal_blood-brain_barrier1.21188199
60MP0005365_abnormal_bile_salt1.20816548
61MP0008260_abnormal_autophagy1.17593839
62MP0003300_gastrointestinal_ulcer1.15728671
63MP0002254_reproductive_system_inflammat1.13084045
64MP0010307_abnormal_tumor_latency1.11080561
65MP0005076_abnormal_cell_differentiation1.08760835
66MP0002722_abnormal_immune_system1.05221668
67MP0002277_abnormal_respiratory_mucosa1.04777898
68MP0000371_diluted_coat_color1.04385547
69MP0003879_abnormal_hair_cell1.04166120
70MP0003634_abnormal_glial_cell1.03332210
71MP0003279_aneurysm1.02066941
72MP0009763_increased_sensitivity_to1.01981326
73MP0005165_increased_susceptibility_to1.00574923
74MP0005164_abnormal_response_to1.00504375
75MP0002138_abnormal_hepatobiliary_system1.00102900
76MP0008004_abnormal_stomach_pH0.99239818
77MP0000015_abnormal_ear_pigmentation0.97788250
78MP0003828_pulmonary_edema0.97460796
79MP0004858_abnormal_nervous_system0.96907498
80MP0004782_abnormal_surfactant_physiolog0.94271294
81MP0001851_eye_inflammation0.91584525
82MP0005390_skeleton_phenotype0.91232319
83MP0003186_abnormal_redox_activity0.87697939
84MP0008874_decreased_physiological_sensi0.84929699
85MP0003633_abnormal_nervous_system0.83493548
86MP0003806_abnormal_nucleotide_metabolis0.81548793
87MP0001958_emphysema0.78210010
88MP0003656_abnormal_erythrocyte_physiolo0.76478049
89MP0003195_calcinosis0.76275169
90MP0002933_joint_inflammation0.75862400
91MP0005257_abnormal_intraocular_pressure0.75722089
92MP0000249_abnormal_blood_vessel0.75466671
93MP0001542_abnormal_bone_strength0.72661844
94MP0005083_abnormal_biliary_tract0.71397923
95MP0003091_abnormal_cell_migration0.71394020
96MP0003566_abnormal_cell_adhesion0.70022215
97MP0005584_abnormal_enzyme/coenzyme_acti0.69790440
98MP0005595_abnormal_vascular_smooth0.68895216
99MP0002971_abnormal_brown_adipose0.68118368
100MP0002332_abnormal_exercise_endurance0.67667099
101MP0001501_abnormal_sleep_pattern0.66207217
102MP0004808_abnormal_hematopoietic_stem0.66182687
103MP0006054_spinal_hemorrhage0.65990265
104MP0003632_abnormal_nervous_system0.65328692
105MP0009115_abnormal_fat_cell0.65197805
106MP0003795_abnormal_bone_structure0.65196293
107MP0005535_abnormal_body_temperature0.64645859
108MP0001873_stomach_inflammation0.64567087
109MP0002118_abnormal_lipid_homeostasis0.63393522
110MP0002136_abnormal_kidney_physiology0.62953213
111MP0005023_abnormal_wound_healing0.62431899
112MP0000747_muscle_weakness0.61746410
113MP0003453_abnormal_keratinocyte_physiol0.60590869
114MP0003631_nervous_system_phenotype0.60171862
115MP0005360_urolithiasis0.55747483
116MP0000767_abnormal_smooth_muscle0.54469366
117MP0000490_abnormal_crypts_of0.52199449
118MP0003763_abnormal_thymus_physiology0.51837713
119MP0002090_abnormal_vision0.51275262
120MP0002693_abnormal_pancreas_physiology0.50828159
121MP0004883_abnormal_blood_vessel0.49203428
122MP0001663_abnormal_digestive_system0.48578813
123MP0003045_fibrosis0.48101753
124MP0000465_gastrointestinal_hemorrhage0.47476828
125MP0000920_abnormal_myelination0.46900160
126MP0010386_abnormal_urinary_bladder0.46890539
127MP0003866_abnormal_defecation0.45310597

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)7.62933124
2Recurrent bacterial skin infections (HP:0005406)7.21809310
3Eczematoid dermatitis (HP:0000976)7.04810468
4Recurrent gram-negative bacterial infections (HP:0005420)6.19767691
5Mediastinal lymphadenopathy (HP:0100721)5.40924037
6Abnormality of macrophages (HP:0004311)5.34472506
7Increased cerebral lipofuscin (HP:0011813)4.63380361
8Autoimmune thrombocytopenia (HP:0001973)4.57655595
9Vacuolated lymphocytes (HP:0001922)4.52014776
10Elevated erythrocyte sedimentation rate (HP:0003565)4.49591572
11Systemic lupus erythematosus (HP:0002725)4.43091164
12Increased neuronal autofluorescent lipopigment (HP:0002074)4.33260844
13Recurrent skin infections (HP:0001581)4.32311995
14Gingivitis (HP:0000230)4.27486611
15Orchitis (HP:0100796)4.00571300
16Stomatitis (HP:0010280)3.99837816
17Myositis (HP:0100614)3.99510828
18Retrobulbar optic neuritis (HP:0100654)3.91937384
19Optic neuritis (HP:0100653)3.91937384
20Chronic obstructive pulmonary disease (HP:0006510)3.90399242
21Obstructive lung disease (HP:0006536)3.90399242
22Complement deficiency (HP:0004431)3.89478548
23Recurrent fungal infections (HP:0002841)3.88034690
24Neurofibrillary tangles (HP:0002185)3.71436305
25Mutism (HP:0002300)3.70655736
26Vasculitis (HP:0002633)3.68758436
27Recurrent viral infections (HP:0004429)3.54205465
28Abnormality of liposaccharide metabolism (HP:0010968)3.38279005
29Abnormality of glycosphingolipid metabolism (HP:0004343)3.38279005
30Abnormality of glycolipid metabolism (HP:0010969)3.38279005
31Axonal loss (HP:0003447)3.32892340
32Periodontitis (HP:0000704)3.32124624
33Basal ganglia calcification (HP:0002135)3.18259397
34Prostate neoplasm (HP:0100787)3.17304970
35Increased IgM level (HP:0003496)3.16895469
36Glomerulonephritis (HP:0000099)3.15149645
37Abnormality of complement system (HP:0005339)3.14873143
38Disinhibition (HP:0000734)3.09414212
39Cellulitis (HP:0100658)3.04437080
40Thick nail (HP:0001805)3.03889114
41Pulmonary infiltrates (HP:0002113)2.98751837
42Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.92681401
43Dysostosis multiplex (HP:0000943)2.92255356
44Pustule (HP:0200039)2.87120353
45Urticaria (HP:0001025)2.86490122
46Recurrent cutaneous fungal infections (HP:0011370)2.81359598
47Chronic mucocutaneous candidiasis (HP:0002728)2.81359598
48Purpura (HP:0000979)2.78215672
49Meningitis (HP:0001287)2.74578801
50Recurrent pneumonia (HP:0006532)2.72395890
51Osteomyelitis (HP:0002754)2.71544590
52Nuclear cataract (HP:0100018)2.70873590
53Interstitial pulmonary disease (HP:0006530)2.70401546
54Neuronal loss in central nervous system (HP:0002529)2.70366291
55Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.69582181
56Hematochezia (HP:0002573)2.68018847
57Tetraparesis (HP:0002273)2.65333194
58Cerebral inclusion bodies (HP:0100314)2.60413870
59Arterial thrombosis (HP:0004420)2.55730380
60Loss of speech (HP:0002371)2.53615635
61Myocardial infarction (HP:0001658)2.51614682
62Leukocytosis (HP:0001974)2.51392322
63Premature loss of primary teeth (HP:0006323)2.51206935
64Chronic otitis media (HP:0000389)2.50365356
65Gastrointestinal infarctions (HP:0005244)2.48422736
66Asymmetric septal hypertrophy (HP:0001670)2.44581743
67Hypergammaglobulinemia (HP:0010702)2.43202771
68Nephritis (HP:0000123)2.39307859
69Hemoptysis (HP:0002105)2.39181056
70Apathy (HP:0000741)2.36542338
71Mucopolysacchariduria (HP:0008155)2.35098719
72Urinary glycosaminoglycan excretion (HP:0003541)2.35098719
73Gingival bleeding (HP:0000225)2.34884730
74Recurrent lower respiratory tract infections (HP:0002783)2.30237567
75Abnormality of glycosaminoglycan metabolism (HP:0004371)2.28410596
76Abnormality of mucopolysaccharide metabolism (HP:0011020)2.28410596
77Abnormality of polysaccharide metabolism (HP:0011012)2.28410596
78Diminished motivation (HP:0000745)2.27652837
79Bone pain (HP:0002653)2.26965292
80Malnutrition (HP:0004395)2.26493943
81Pathologic fracture (HP:0002756)2.22397148
82Keratoconjunctivitis sicca (HP:0001097)2.21665386
83Increased serum ferritin (HP:0003281)2.21183057
84Hepatosplenomegaly (HP:0001433)2.17497348
85Supranuclear gaze palsy (HP:0000605)2.15743830
86Poor head control (HP:0002421)2.14933359
87Increased CSF protein (HP:0002922)2.12427674
88Colitis (HP:0002583)2.12240313
89Dementia (HP:0000726)2.11360533
90Abnormality of the periventricular white matter (HP:0002518)2.10745004
91Progressive visual loss (HP:0000529)2.08876410
92Joint hemorrhage (HP:0005261)2.08004789
93Agnosia (HP:0010524)2.07982408
94Eosinophilia (HP:0001880)2.06647109
95Keratoconjunctivitis (HP:0001096)2.05524751
96Memory impairment (HP:0002354)2.05496658
97Porencephaly (HP:0002132)2.05106160
98Petechiae (HP:0000967)2.03241712
99Progressive neurologic deterioration (HP:0002344)2.02655684
100Osteolytic defects of the phalanges of the hand (HP:0009771)2.01720192
101Osteolytic defects of the hand bones (HP:0009699)2.01720192
102Pulmonary embolism (HP:0002204)1.99070928
103Abnormality of the prostate (HP:0008775)1.97691064
104Xanthomatosis (HP:0000991)1.96105573
105Sepsis (HP:0100806)1.94440085
106Arthralgia (HP:0002829)1.93372442
107Abnormality of the pleura (HP:0002103)1.92659574
108Abnormality of the pericardium (HP:0001697)1.91939865
109Inappropriate behavior (HP:0000719)1.91508554
110Vertebral compression fractures (HP:0002953)1.91387360
111Spontaneous hematomas (HP:0007420)1.91327193
112Personality changes (HP:0000751)1.89172799
113Amyloidosis (HP:0011034)1.88798891
114Gastrointestinal stroma tumor (HP:0100723)1.88665727
115Abnormality of iron homeostasis (HP:0011031)1.88138338
116Inflammation of the large intestine (HP:0002037)1.85612090
117Neoplasm of head and neck (HP:0012288)1.85244939
118Esophageal neoplasm (HP:0100751)1.85244939
119Upper motor neuron abnormality (HP:0002127)1.84732388
120Skin ulcer (HP:0200042)1.84086093
121Global brain atrophy (HP:0002283)1.84063653
122Restrictive lung disease (HP:0002091)1.83218367
123Abnormality of the vasculature of the conjunctiva (HP:0008054)1.83093043
124Vertigo (HP:0002321)1.83028370
125Frequent falls (HP:0002359)1.82805387
126Nasal polyposis (HP:0100582)1.81585090
127Diplopia (HP:0000651)1.80021369
128Abnormality of binocular vision (HP:0011514)1.80021369
129Increased IgE level (HP:0003212)1.79570590
130Chest pain (HP:0100749)1.79312768
131Cerebral aneurysm (HP:0004944)1.79279782
132Retinal atrophy (HP:0001105)1.77680562
133Peripheral demyelination (HP:0011096)1.77636001
134Polyneuropathy (HP:0001271)1.76292929
135Acne (HP:0001061)1.74267299

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK44.91196273
2MAP3K144.84755967
3TYK23.72826646
4IRAK43.67591118
5TBK13.62810397
6BLK3.59281474
7IRAK33.49976662
8PBK2.99016803
9IKBKE2.93796658
10MAP4K12.55415749
11IKBKB2.52262629
12JAK32.41058650
13PRPF4B2.29586480
14MAP3K132.26580060
15JAK12.26547307
16KIT2.09688101
17ERN11.89860038
18DDR21.85539036
19TXK1.73770830
20TNK21.69726010
21CHUK1.69314630
22CDC42BPA1.59282293
23PIM21.58260738
24CSK1.57585399
25TAOK31.48403661
26SYK1.47585445
27CSF1R1.43303986
28HCK1.33729397
29MAP3K31.33444341
30ZAP701.30011953
31FGR1.23057756
32LYN1.19635834
33MARK31.16065594
34JAK21.15393679
35NEK91.14013905
36MATK1.13273267
37TAOK21.10235348
38LCK1.09411762
39MAPK121.05787947
40BTK1.05464062
41TYRO31.00075590
42EPHB10.99274624
43BMPR20.98962550
44TAOK10.97484868
45PIM10.97073533
46FES0.95999940
47RPS6KA40.94788415
48STK40.94032823
49MARK20.92161786
50MAPK70.91407460
51ABL20.91338219
52YES10.89170133
53TGFBR20.87934646
54IRAK20.81820668
55BMX0.79244902
56SIK20.77825555
57EIF2AK20.77138007
58TEC0.76626034
59MAP3K50.76124494
60GRK70.74644636
61NME20.74472060
62IRAK10.73365624
63SIK30.71802702
64MAP2K60.71555297
65EGFR0.70754359
66FGFR30.70471902
67MST1R0.70346938
68STK100.69315297
69CAMKK20.68577029
70PRKCD0.68342831
71TRPM70.67802371
72TRIB30.66724318
73ABL10.66646769
74CLK10.64910361
75PTK60.63663542
76CAMK1D0.63165677
77DAPK20.62457604
78MST40.62380174
79NTRK30.60924006
80RIPK10.60156487
81SGK30.59923064
82MUSK0.58390367
83PDGFRA0.58315956
84MAP3K100.56573259
85PIK3CG0.55226524
86MAPK40.54024801
87CAMKK10.53985722
88BMPR1B0.53461309
89KSR20.52472104
90FGFR40.50614180
91MAP2K30.49997409
92STK30.49830926
93ARAF0.49205289
94TTN0.48806453
95ROCK20.48384065
96ERBB30.47368286
97PRKD20.46126112
98NTRK20.46045743
99SGK20.45830432
100PRKCQ0.45467099
101RET0.42412923
102MAP3K60.42042027
103HIPK20.41471746
104PRKD10.41426094
105CDK60.40129852
106MAP3K70.39975580
107CAMK2G0.39487563
108PRKAA20.38438874
109FYN0.37591237
110PDK20.37047772
111PDPK10.36432214
112MAPKAPK20.36308593
113DMPK0.34987491
114PDK10.34776810
115RPS6KA60.34640200
116DAPK30.34111861
117EPHA30.33918014
118PRKG20.32921045
119PKN10.30562578
120LRRK20.30124372
121ITK0.29643036
122CDK120.28858654
123MAP3K110.28634825
124SCYL20.27378140
125RPS6KA20.26770772
126ADRBK20.25351910
127MOS0.24009118
128CAMK1G0.23293115
129IGF1R0.22507524
130PDGFRB0.22130541
131RPS6KC10.20154489
132RPS6KL10.20154489
133PLK20.19826585
134MAP3K10.18780552
135NUAK10.16322525
136ERBB40.16250607

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051403.49608549
2Toll-like receptor signaling pathway_Homo sapiens_hsa046203.05266770
3Staphylococcus aureus infection_Homo sapiens_hsa051503.01083204
4Graft-versus-host disease_Homo sapiens_hsa053322.96745779
5NF-kappa B signaling pathway_Homo sapiens_hsa040642.72804665
6NOD-like receptor signaling pathway_Homo sapiens_hsa046212.59858126
7Legionellosis_Homo sapiens_hsa051342.57969938
8Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.54310573
9Osteoclast differentiation_Homo sapiens_hsa043802.52934259
10Pertussis_Homo sapiens_hsa051332.50964939
11Allograft rejection_Homo sapiens_hsa053302.48996697
12Tuberculosis_Homo sapiens_hsa051522.35864960
13RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.28675099
14Malaria_Homo sapiens_hsa051442.16913795
15Measles_Homo sapiens_hsa051622.16265594
16Rheumatoid arthritis_Homo sapiens_hsa053232.16230398
17Influenza A_Homo sapiens_hsa051642.03460105
18TNF signaling pathway_Homo sapiens_hsa046682.02681504
19Lysosome_Homo sapiens_hsa041422.00984999
20Asthma_Homo sapiens_hsa053101.91357209
21Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.87082527
22B cell receptor signaling pathway_Homo sapiens_hsa046621.80165288
23Type I diabetes mellitus_Homo sapiens_hsa049401.79908701
24Phagosome_Homo sapiens_hsa041451.75137827
25Intestinal immune network for IgA production_Homo sapiens_hsa046721.74844802
26Salmonella infection_Homo sapiens_hsa051321.70507586
27African trypanosomiasis_Homo sapiens_hsa051431.70057334
28Toxoplasmosis_Homo sapiens_hsa051451.64822260
29Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.60306283
30Herpes simplex infection_Homo sapiens_hsa051681.56680296
31Glycosaminoglycan degradation_Homo sapiens_hsa005311.49665356
32Other glycan degradation_Homo sapiens_hsa005111.46552422
33Apoptosis_Homo sapiens_hsa042101.41283884
34Chemokine signaling pathway_Homo sapiens_hsa040621.40782711
35Hematopoietic cell lineage_Homo sapiens_hsa046401.36921424
36Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.33508383
37Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.33197310
38Shigellosis_Homo sapiens_hsa051311.28744495
39Antigen processing and presentation_Homo sapiens_hsa046121.26930220
40Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.24826116
41Jak-STAT signaling pathway_Homo sapiens_hsa046301.21328949
42Hepatitis C_Homo sapiens_hsa051601.19250010
43Hepatitis B_Homo sapiens_hsa051611.13312458
44Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.09339220
45Autoimmune thyroid disease_Homo sapiens_hsa053201.06612920
46Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.00820322
47Viral myocarditis_Homo sapiens_hsa054160.98775615
48AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.94625517
49PPAR signaling pathway_Homo sapiens_hsa033200.94393485
50Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.89533498
51Primary immunodeficiency_Homo sapiens_hsa053400.87207907
52Amoebiasis_Homo sapiens_hsa051460.85640628
53Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.83019132
54Leukocyte transendothelial migration_Homo sapiens_hsa046700.81487701
55Collecting duct acid secretion_Homo sapiens_hsa049660.80065223
56Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.76155510
57T cell receptor signaling pathway_Homo sapiens_hsa046600.75953377
58Prion diseases_Homo sapiens_hsa050200.73314453
59Acute myeloid leukemia_Homo sapiens_hsa052210.71950015
60Neurotrophin signaling pathway_Homo sapiens_hsa047220.71380642
61Caffeine metabolism_Homo sapiens_hsa002320.68631070
62Chronic myeloid leukemia_Homo sapiens_hsa052200.67755237
63Prolactin signaling pathway_Homo sapiens_hsa049170.67642453
64Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.67552154
65Type II diabetes mellitus_Homo sapiens_hsa049300.67383290
66Adipocytokine signaling pathway_Homo sapiens_hsa049200.66257421
67Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.62823841
68Complement and coagulation cascades_Homo sapiens_hsa046100.62242542
69Phospholipase D signaling pathway_Homo sapiens_hsa040720.61358447
70Epstein-Barr virus infection_Homo sapiens_hsa051690.61239714
71Primary bile acid biosynthesis_Homo sapiens_hsa001200.59822199
72SNARE interactions in vesicular transport_Homo sapiens_hsa041300.59598853
73Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.56979109
74Pancreatic cancer_Homo sapiens_hsa052120.56807258
75GnRH signaling pathway_Homo sapiens_hsa049120.54586662
76Platelet activation_Homo sapiens_hsa046110.53543269
77Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.50428351
78Sphingolipid signaling pathway_Homo sapiens_hsa040710.50106132
79Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.49588616
80Histidine metabolism_Homo sapiens_hsa003400.48342081
81Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.44920288
82Galactose metabolism_Homo sapiens_hsa000520.43531775
83Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.43416144
84Renin secretion_Homo sapiens_hsa049240.42735557
85Synaptic vesicle cycle_Homo sapiens_hsa047210.42600508
86Small cell lung cancer_Homo sapiens_hsa052220.41980252
87Bile secretion_Homo sapiens_hsa049760.39518690
88Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.38380280
89HIF-1 signaling pathway_Homo sapiens_hsa040660.38339674
90Estrogen signaling pathway_Homo sapiens_hsa049150.38327912
91Insulin resistance_Homo sapiens_hsa049310.38134420
92Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.36270354
93Viral carcinogenesis_Homo sapiens_hsa052030.35795054
94Fructose and mannose metabolism_Homo sapiens_hsa000510.35430787
95Transcriptional misregulation in cancer_Homo sapiens_hsa052020.33840724
96Mineral absorption_Homo sapiens_hsa049780.32436555
97Renal cell carcinoma_Homo sapiens_hsa052110.31731268
98Carbohydrate digestion and absorption_Homo sapiens_hsa049730.31725327
99Sphingolipid metabolism_Homo sapiens_hsa006000.28596200
100Bladder cancer_Homo sapiens_hsa052190.27919621
101Notch signaling pathway_Homo sapiens_hsa043300.27666434
102Gastric acid secretion_Homo sapiens_hsa049710.27612542
103Regulation of actin cytoskeleton_Homo sapiens_hsa048100.27141784
104Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.26404069
105Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.25980405
106Dorso-ventral axis formation_Homo sapiens_hsa043200.25183315
107Endocytosis_Homo sapiens_hsa041440.24242846
108VEGF signaling pathway_Homo sapiens_hsa043700.23180961
109Vibrio cholerae infection_Homo sapiens_hsa051100.21761451
110Pentose and glucuronate interconversions_Homo sapiens_hsa000400.21022472
111Proteoglycans in cancer_Homo sapiens_hsa052050.20970668
112HTLV-I infection_Homo sapiens_hsa051660.18269245
113FoxO signaling pathway_Homo sapiens_hsa040680.16993303
114Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.12561802
115Renin-angiotensin system_Homo sapiens_hsa046140.10425511
116MAPK signaling pathway_Homo sapiens_hsa040100.10267365
117ABC transporters_Homo sapiens_hsa020100.10127235
118mTOR signaling pathway_Homo sapiens_hsa041500.09489277
119MicroRNAs in cancer_Homo sapiens_hsa052060.09227799
120Prostate cancer_Homo sapiens_hsa052150.08438627

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