RAB32

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene anchors the type II regulatory subunit of protein kinase A to the mitochondrion and aids in mitochondrial fission. The encoded protein also appears to be involved in autophagy and melanosome secretion. Variations in this gene may be linked to leprosy. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neutrophil activation involved in immune response (GO:0002283)5.59283853
2antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.43961130
3response to peptidoglycan (GO:0032494)5.00463345
4positive regulation by symbiont of host defense response (GO:0052509)4.79852079
5modulation by symbiont of host defense response (GO:0052031)4.79852079
6modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.79852079
7modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.79852079
8positive regulation by organism of defense response of other organism involved in symbiotic interact4.79852079
9modulation by symbiont of host immune response (GO:0052553)4.79852079
10respiratory burst (GO:0045730)4.42025729
11immunoglobulin mediated immune response (GO:0016064)4.34046765
12pinocytosis (GO:0006907)4.20099676
13production of molecular mediator involved in inflammatory response (GO:0002532)4.19891558
14hydrogen peroxide biosynthetic process (GO:0050665)4.13671073
15reactive oxygen species biosynthetic process (GO:1903409)4.10721514
16positive regulation of interferon-alpha production (GO:0032727)4.08050385
17positive regulation of heterotypic cell-cell adhesion (GO:0034116)4.02793907
18macrophage activation involved in immune response (GO:0002281)3.95028318
19granulocyte activation (GO:0036230)3.87248424
20positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.84852554
21regulation of interferon-alpha production (GO:0032647)3.84446963
22positive regulation of chemokine biosynthetic process (GO:0045080)3.76833573
23lipopolysaccharide-mediated signaling pathway (GO:0031663)3.76462701
24neutrophil activation (GO:0042119)3.73820052
25regulation of chemokine biosynthetic process (GO:0045073)3.69844820
26regulation of leukocyte degranulation (GO:0043300)3.67215959
27regulation of interferon-beta biosynthetic process (GO:0045357)3.65910590
28cellular response to thyroid hormone stimulus (GO:0097067)3.62248805
29regulation of myeloid leukocyte mediated immunity (GO:0002886)3.61469628
30positive regulation of leukocyte degranulation (GO:0043302)3.61075483
31antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.51899299
32antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.51899299
33positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.49103960
34myeloid cell activation involved in immune response (GO:0002275)3.41004163
35leukocyte aggregation (GO:0070486)3.38615903
36glycosphingolipid catabolic process (GO:0046479)3.36613213
37defense response to protozoan (GO:0042832)3.33870135
38neutrophil mediated immunity (GO:0002446)3.33605184
39superoxide anion generation (GO:0042554)3.31059645
40response to interferon-beta (GO:0035456)3.31009229
41response to host immune response (GO:0052572)3.30719912
42response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.30719912
43antigen processing and presentation of endogenous antigen (GO:0019883)3.29663548
44response to interferon-alpha (GO:0035455)3.29477790
45B cell mediated immunity (GO:0019724)3.28273939
46response to thyroid hormone (GO:0097066)3.26814872
47cellular response to type I interferon (GO:0071357)3.25658328
48type I interferon signaling pathway (GO:0060337)3.25658328
49detection of molecule of bacterial origin (GO:0032490)3.25255590
50T-helper 1 type immune response (GO:0042088)3.24878811
51negative regulation of nitric oxide biosynthetic process (GO:0045019)3.22912092
52hyaluronan catabolic process (GO:0030214)3.22103736
53response to type I interferon (GO:0034340)3.22095108
54negative regulation of erythrocyte differentiation (GO:0045647)3.22039884
55cellular extravasation (GO:0045123)3.21364082
56barbed-end actin filament capping (GO:0051016)3.20480527
57cellular response to interferon-beta (GO:0035458)3.17196870
58response to muramyl dipeptide (GO:0032495)3.16565528
59phagocytosis, engulfment (GO:0006911)3.15568915
60regulation of superoxide anion generation (GO:0032928)3.13858939
61cellular response to exogenous dsRNA (GO:0071360)3.13658464
62modulation of growth of symbiont involved in interaction with host (GO:0044144)3.13251128
63regulation of growth of symbiont in host (GO:0044126)3.13251128
64negative regulation of growth of symbiont in host (GO:0044130)3.13251128
65negative regulation of growth of symbiont involved in interaction with host (GO:0044146)3.13251128
66regulation of syncytium formation by plasma membrane fusion (GO:0060142)3.08010707
67positive regulation of interferon-beta production (GO:0032728)3.06066523
68leukocyte mediated cytotoxicity (GO:0001909)3.00903697
69negative regulation of myeloid cell apoptotic process (GO:0033033)3.00892358
70glycolipid catabolic process (GO:0019377)3.00532220
71response to protozoan (GO:0001562)2.99171130
72lipoxygenase pathway (GO:0019372)2.97878128
73positive regulation of cellular amide metabolic process (GO:0034250)2.96947455
74response to host (GO:0075136)2.96064330
75response to host defenses (GO:0052200)2.96064330
76response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.96064330
77mature B cell differentiation involved in immune response (GO:0002313)2.95721929
78cellular response to zinc ion (GO:0071294)2.94776210
79interferon-gamma-mediated signaling pathway (GO:0060333)2.93180362
80killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.92846132
81disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.92846132
82positive regulation of mast cell degranulation (GO:0043306)2.92490293
83positive regulation of mast cell activation involved in immune response (GO:0033008)2.92490293
84regulation of heterotypic cell-cell adhesion (GO:0034114)2.91776089
85positive regulation of mast cell activation (GO:0033005)2.89363076
86macrophage activation (GO:0042116)2.89353003
87regulation of mast cell degranulation (GO:0043304)2.88463664
88regulation of mast cell activation (GO:0033003)2.87770660
89Arp2/3 complex-mediated actin nucleation (GO:0034314)2.86931444
90protein localization to endosome (GO:0036010)2.86696687
91regulation of interleukin-8 biosynthetic process (GO:0045414)2.85885435
92adenosine receptor signaling pathway (GO:0001973)2.85746148
93positive regulation of antigen processing and presentation (GO:0002579)2.85576363
94natural killer cell mediated cytotoxicity (GO:0042267)2.84809920
95natural killer cell mediated immunity (GO:0002228)2.84809920
96negative regulation of viral genome replication (GO:0045071)2.83992195
97regulation of B cell receptor signaling pathway (GO:0050855)2.82282153
98positive regulation of B cell differentiation (GO:0045579)2.82057834
99detection of external biotic stimulus (GO:0098581)2.80323431
100membrane invagination (GO:0010324)2.79011849
101microglial cell activation (GO:0001774)2.77772214
102angiogenesis involved in wound healing (GO:0060055)2.77287917
103positive regulation of natural killer cell differentiation (GO:0032825)2.76281239
104regulation of early endosome to late endosome transport (GO:2000641)2.76046575
105positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.75852264
106oligosaccharide catabolic process (GO:0009313)2.75777374
107positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.75615013
108regulation of regulated secretory pathway (GO:1903305)2.74602385
109detection of bacterium (GO:0016045)2.73163373
110positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.72868577
111positive regulation of heat generation (GO:0031652)2.72742957
112negative regulation of interleukin-17 production (GO:0032700)2.72110664
113myeloid leukocyte mediated immunity (GO:0002444)2.71801270
114positive regulation of toll-like receptor signaling pathway (GO:0034123)2.70909560
115response to fungus (GO:0009620)2.70734811
116regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.70315396
117regulation of mast cell activation involved in immune response (GO:0033006)2.69568549
118regulation of RIG-I signaling pathway (GO:0039535)2.68705886
119amino sugar catabolic process (GO:0046348)2.68596592
120regulation of platelet activation (GO:0010543)2.68426110
121thrombin receptor signaling pathway (GO:0070493)2.68259618
122regulation of fever generation (GO:0031620)2.68135241
123platelet aggregation (GO:0070527)2.67748502
124positive regulation of monocyte chemotaxis (GO:0090026)2.67511062
125NIK/NF-kappaB signaling (GO:0038061)2.67113869
126positive regulation of gamma-delta T cell activation (GO:0046645)2.66418678
127negative regulation of interleukin-12 production (GO:0032695)2.66378695
128positive regulation of tumor necrosis factor production (GO:0032760)2.65855859
129myeloid leukocyte activation (GO:0002274)2.65464102
130positive regulation of NF-kappaB import into nucleus (GO:0042346)2.64932387
131regulation of monocyte chemotaxis (GO:0090025)2.64455693
132detection of other organism (GO:0098543)2.64442904
133positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.64208013
134lymphocyte chemotaxis (GO:0048247)2.64049096
135regulation of platelet aggregation (GO:0090330)2.59855598
136cyclooxygenase pathway (GO:0019371)2.58691725
137stress fiber assembly (GO:0043149)2.55662036
138fibril organization (GO:0097435)2.55647336
139positive regulation of receptor recycling (GO:0001921)2.55621195
140positive regulation of regulated secretory pathway (GO:1903307)2.55542021
141ceramide catabolic process (GO:0046514)2.54977418
142cellular response to arsenic-containing substance (GO:0071243)2.53421297
143regulation of integrin-mediated signaling pathway (GO:2001044)2.53112864
144melanin biosynthetic process (GO:0042438)2.51568882
145detection of biotic stimulus (GO:0009595)2.49536267
146deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.46953836
147regulation of tumor necrosis factor superfamily cytokine production (GO:1903555)2.44176081
148leukocyte migration involved in inflammatory response (GO:0002523)2.44064845
149leukocyte degranulation (GO:0043299)2.43886100
150extracellular fibril organization (GO:0043206)2.42989658
151regulation of T-helper 2 cell differentiation (GO:0045628)2.42938460
152hypotonic response (GO:0006971)2.38959125
153platelet degranulation (GO:0002576)2.38671587
154regulation of tumor necrosis factor production (GO:0032680)2.37336384
155regulation of superoxide metabolic process (GO:0090322)2.36676537
156regulation of T cell tolerance induction (GO:0002664)2.34354938
157regulation of tolerance induction (GO:0002643)2.34162027
158G-protein coupled purinergic receptor signaling pathway (GO:0035588)2.30147545

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_21731497_ChIP-ChIP_J774_Mouse6.00136132
2IRF8_22096565_ChIP-ChIP_GC-B_Human5.95070933
3BP1_19119308_ChIP-ChIP_Hs578T_Human5.34614480
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.86315792
5IRF8_27001747_Chip-Seq_BMDM_Mouse3.79589350
6IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.69066817
7* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.68839727
8* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.47583502
9MYB_21317192_ChIP-Seq_ERMYB_Mouse3.32634084
10MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.28718789
11ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.12233352
12Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.04629588
13RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.70866866
14SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.63973986
15EGR1_19374776_ChIP-ChIP_THP-1_Human2.55814039
16* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.50305086
17FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.49675867
18EGR1_23403033_ChIP-Seq_LIVER_Mouse2.39252002
19STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.37044315
20STAT4_19710469_ChIP-ChIP_TH1__Mouse2.30309779
21CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.29796797
22RXR_22158963_ChIP-Seq_LIVER_Mouse2.25833048
23* SPI1_23547873_ChIP-Seq_NB4_Human2.23480709
24* BRD4_27068464_Chip-Seq_AML-cells_Mouse2.22406380
25STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.12993042
26RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.11456608
27STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.05476542
28PPARA_22158963_ChIP-Seq_LIVER_Mouse2.04600425
29SCL_19346495_ChIP-Seq_HPC-7_Human2.04574461
30* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.84030395
31ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.78679758
32PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.74939670
33VDR_24763502_ChIP-Seq_THP-1_Human1.73492475
34CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.72619397
35NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.69978475
36GATA1_22025678_ChIP-Seq_K562_Human1.69280457
37LXR_22292898_ChIP-Seq_THP-1_Human1.69248600
38LXR_22158963_ChIP-Seq_LIVER_Mouse1.69008217
39FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.68842543
40* PU_27001747_Chip-Seq_BMDM_Mouse1.67477626
41MYB_26560356_Chip-Seq_TH2_Human1.63805139
42RUNX1_22412390_ChIP-Seq_EML_Mouse1.62258747
43CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.61242308
44CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.59214798
45PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.54957591
46SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.51125687
47STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.48934787
48TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.48744803
49MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.46997764
50VDR_21846776_ChIP-Seq_THP-1_Human1.43033907
51MAF_26560356_Chip-Seq_TH1_Human1.42058506
52RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.42044696
53SRY_22984422_ChIP-ChIP_TESTIS_Rat1.40554294
54LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.39960119
55CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.39606980
56CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.38275519
57LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.37116276
58GATA1_19941826_ChIP-Seq_K562_Human1.36815736
59KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.34725400
60KDM2B_26808549_Chip-Seq_SUP-B15_Human1.34044497
61GATA2_22383799_ChIP-Seq_G1ME_Mouse1.33584635
62FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.33496729
63THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.33086248
64MYB_26560356_Chip-Seq_TH1_Human1.32851838
65SPI1_23127762_ChIP-Seq_K562_Human1.30425067
66CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.29781711
67PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.29646834
68PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.29527316
69* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.28816976
70RUNX_20019798_ChIP-Seq_JUKART_Human1.28738174
71PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.24771582
72GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.21756552
73FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.21360750
74SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.18631664
75TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.18600369
76VDR_24787735_ChIP-Seq_THP-1_Human1.16707643
77SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.16509291
78NCOR1_26117541_ChIP-Seq_K562_Human1.13225902
79MYC_22102868_ChIP-Seq_BL_Human1.11556925
80* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.11264118
81PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.10883622
82CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.10545263
83ELF1_20517297_ChIP-Seq_JURKAT_Human1.10403045
84GATA3_26560356_Chip-Seq_TH2_Human1.10244870
85JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.10142777
86GATA1_22383799_ChIP-Seq_G1ME_Mouse1.09590385
87ELF1_17652178_ChIP-ChIP_JURKAT_Human1.08577390
88GATA2_21666600_ChIP-Seq_HMVEC_Human1.06897508
89* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05820515
90TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.04339826
91SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.03684406
92RARG_19884340_ChIP-ChIP_MEFs_Mouse1.03086314
93HOXB4_20404135_ChIP-ChIP_EML_Mouse1.02600289
94UTX_26944678_Chip-Seq_JUKART_Human1.01441764
95VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.01306651
96E2F7_22180533_ChIP-Seq_HELA_Human1.01055748
97JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.00530208
98BCL6_27268052_Chip-Seq_Bcells_Human1.00189278
99GATA3_27048872_Chip-Seq_THYMUS_Human0.98871523
100* GATA2_19941826_ChIP-Seq_K562_Human0.98012846
101KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.97701272
102CTCF_27219007_Chip-Seq_ERYTHROID_Human0.97580239
103ERG_20887958_ChIP-Seq_HPC-7_Mouse0.97465774
104RACK7_27058665_Chip-Seq_MCF-7_Human0.97037673
105E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.95723343
106TFEB_21752829_ChIP-Seq_HELA_Human0.94693933
107TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94130172
108TP63_17297297_ChIP-ChIP_HaCaT_Human0.93930063
109GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.89783426
110* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.86587800
111ELK3_25401928_ChIP-Seq_HUVEC_Human0.84685661
112PU.1_20513432_ChIP-Seq_Bcells_Mouse0.81508950
113CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.80395348
114TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.79238917
115TCF7_22412390_ChIP-Seq_EML_Mouse0.78687422
116GATA1_19941827_ChIP-Seq_MEL_Mouse0.76897075
117SPI1_20517297_ChIP-Seq_HL60_Human0.75283900
118SOX2_20726797_ChIP-Seq_SW620_Human0.74000187
119MAF_26560356_Chip-Seq_TH2_Human0.73400339
120EGR1_19032775_ChIP-ChIP_M12_Human0.73287282
121NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.72982724
122EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.72682135
123* NRF2_20460467_ChIP-Seq_MEFs_Mouse0.71353576
124* NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.71353576
125SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.69466978

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.13326545
2MP0009785_altered_susceptibility_to3.79251107
3MP0003436_decreased_susceptibility_to3.79056917
4MP0002148_abnormal_hypersensitivity_rea3.22731769
5MP0002419_abnormal_innate_immunity3.09131538
6MP0003724_increased_susceptibility_to2.88935449
7MP0005025_abnormal_response_to2.85407178
8MP0002877_abnormal_melanocyte_morpholog2.78703449
9MP0005000_abnormal_immune_tolerance2.75324318
10MP0006082_CNS_inflammation2.74399991
11MP0003303_peritoneal_inflammation2.69550503
12MP0000685_abnormal_immune_system2.54292592
13MP0005058_abnormal_lysosome_morphology2.49736520
14MP0005387_immune_system_phenotype2.36221692
15MP0001790_abnormal_immune_system2.36221692
16MP0005464_abnormal_platelet_physiology2.33165907
17MP0002452_abnormal_antigen_presenting2.32268330
18MP0002723_abnormal_immune_serum2.17071055
19MP0001800_abnormal_humoral_immune2.14030873
20MP0005671_abnormal_response_to2.12126387
21MP0004510_myositis2.09903810
22MP0009764_decreased_sensitivity_to2.07431068
23MP0001853_heart_inflammation2.05191668
24MP0000015_abnormal_ear_pigmentation2.02195082
25MP0001533_abnormal_skeleton_physiology1.97734513
26MP0001819_abnormal_immune_cell1.96643022
27MP0002420_abnormal_adaptive_immunity1.94021169
28MP0003191_abnormal_cellular_cholesterol1.93099263
29MP0009840_abnormal_foam_cell1.90385495
30MP0001845_abnormal_inflammatory_respons1.86636446
31MP0005171_absent_coat_pigmentation1.80685750
32MP0002006_tumorigenesis1.80155342
33MP0008469_abnormal_protein_level1.80016407
34MP0002139_abnormal_hepatobiliary_system1.77341427
35MP0003172_abnormal_lysosome_physiology1.73437330
36MP0003186_abnormal_redox_activity1.73078151
37MP0003075_altered_response_to1.69862017
38MP0000343_altered_response_to1.69611879
39MP0008260_abnormal_autophagy1.67382186
40MP0004947_skin_inflammation1.67374526
41MP0003279_aneurysm1.66078960
42MP0002405_respiratory_system_inflammati1.65895046
43MP0008004_abnormal_stomach_pH1.64933751
44MP0005360_urolithiasis1.64767928
45MP0000372_irregular_coat_pigmentation1.61838997
46MP0010155_abnormal_intestine_physiology1.59483845
47MP0005257_abnormal_intraocular_pressure1.58246862
48MP0002138_abnormal_hepatobiliary_system1.56611503
49MP0002166_altered_tumor_susceptibility1.46375336
50MP0005397_hematopoietic_system_phenotyp1.46240242
51MP0001545_abnormal_hematopoietic_system1.46240242
52MP0000858_altered_metastatic_potential1.45156978
53MP0003448_altered_tumor_morphology1.44277827
54MP0000716_abnormal_immune_system1.43049251
55MP0005408_hypopigmentation1.41062248
56MP0009333_abnormal_splenocyte_physiolog1.35590045
57MP0001542_abnormal_bone_strength1.32911713
58MP0009278_abnormal_bone_marrow1.31877580
59MP0002398_abnormal_bone_marrow1.30898070
60MP0001958_emphysema1.30488034
61MP0005075_abnormal_melanosome_morpholog1.29886640
62MP0003195_calcinosis1.28396511
63MP0005165_increased_susceptibility_to1.24764762
64MP0002998_abnormal_bone_remodeling1.24601581
65MP0005166_decreased_susceptibility_to1.24289532
66MP0009763_increased_sensitivity_to1.24230853
67MP0000689_abnormal_spleen_morphology1.18841317
68MP0002429_abnormal_blood_cell1.18720826
69MP0000604_amyloidosis1.16909195
70MP0004782_abnormal_surfactant_physiolog1.15708434
71MP0005365_abnormal_bile_salt1.15226306
72MP0005085_abnormal_gallbladder_physiolo1.15205234
73MP0005164_abnormal_response_to1.12781331
74MP0003091_abnormal_cell_migration1.11134169
75MP0002254_reproductive_system_inflammat1.09678110
76MP0003950_abnormal_plasma_membrane1.07153245
77MP0003806_abnormal_nucleotide_metabolis1.06705477
78MP0005083_abnormal_biliary_tract1.06571480
79MP0002722_abnormal_immune_system1.05727370
80MP0004272_abnormal_basement_membrane1.03319439
81MP0005174_abnormal_tail_pigmentation1.02845150
82MP0005167_abnormal_blood-brain_barrier1.02276590
83MP0002396_abnormal_hematopoietic_system1.01359161
84MP0003656_abnormal_erythrocyte_physiolo1.01289997
85MP0005319_abnormal_enzyme/_coenzyme0.98727276
86MP0005310_abnormal_salivary_gland0.97838147
87MP0003300_gastrointestinal_ulcer0.96648353
88MP0000609_abnormal_liver_physiology0.96199705
89MP0005390_skeleton_phenotype0.92953936
90MP0004883_abnormal_blood_vessel0.92395361
91MP0000465_gastrointestinal_hemorrhage0.91005457
92MP0003795_abnormal_bone_structure0.90305390
93MP0001849_ear_inflammation0.89123429
94MP0010329_abnormal_lipoprotein_level0.87456066
95MP0008875_abnormal_xenobiotic_pharmacok0.86304911
96MP0000249_abnormal_blood_vessel0.83656462
97MP0005409_darkened_coat_color0.83495267
98MP0008438_abnormal_cutaneous_collagen0.82870257
99MP0004808_abnormal_hematopoietic_stem0.82336023
100MP0009765_abnormal_xenobiotic_induced0.82170298
101MP0001851_eye_inflammation0.80606180
102MP0005275_abnormal_skin_tensile0.80314281
103MP0002095_abnormal_skin_pigmentation0.79961788
104MP0001663_abnormal_digestive_system0.79799047
105MP0005584_abnormal_enzyme/coenzyme_acti0.79000604
106MP0003705_abnormal_hypodermis_morpholog0.77800668
107MP0003828_pulmonary_edema0.77670026
108MP0000490_abnormal_crypts_of0.77005724
109MP0000598_abnormal_liver_morphology0.76635762
110MP0001764_abnormal_homeostasis0.76520891
111MP0003252_abnormal_bile_duct0.76054553
112MP0010307_abnormal_tumor_latency0.75654729
113MP0001873_stomach_inflammation0.75396633
114MP0003183_abnormal_peptide_metabolism0.74738109
115MP0006054_spinal_hemorrhage0.74697759
116MP0003690_abnormal_glial_cell0.74459667
117MP0000371_diluted_coat_color0.74090654
118MP0005451_abnormal_body_composition0.73489647
119MP0004381_abnormal_hair_follicle0.73008138
120MP0010368_abnormal_lymphatic_system0.72724455
121MP0002933_joint_inflammation0.72063822
122MP0002132_abnormal_respiratory_system0.71621408
123MP0003566_abnormal_cell_adhesion0.71142799
124MP0003453_abnormal_keratinocyte_physiol0.71033213
125MP0005023_abnormal_wound_healing0.69132745
126MP0008873_increased_physiological_sensi0.68081726
127MP0003763_abnormal_thymus_physiology0.67977803

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)6.55314946
2Eczematoid dermatitis (HP:0000976)6.36065576
3Recurrent bacterial skin infections (HP:0005406)6.25585123
4Recurrent gram-negative bacterial infections (HP:0005420)6.20248407
5Abnormality of macrophages (HP:0004311)4.51974765
6Mediastinal lymphadenopathy (HP:0100721)4.49831719
7Elevated erythrocyte sedimentation rate (HP:0003565)4.34926330
8Systemic lupus erythematosus (HP:0002725)4.24401332
9Recurrent skin infections (HP:0001581)4.02101319
10Myositis (HP:0100614)3.96341579
11Vacuolated lymphocytes (HP:0001922)3.91714373
12Autoimmune thrombocytopenia (HP:0001973)3.83683341
13Abnormal platelet volume (HP:0011876)3.72974625
14Increased mean platelet volume (HP:0011877)3.68722606
15Gingivitis (HP:0000230)3.60669562
16Orchitis (HP:0100796)3.45035007
17Chronic obstructive pulmonary disease (HP:0006510)3.37645822
18Obstructive lung disease (HP:0006536)3.37645822
19Recurrent fungal infections (HP:0002841)3.33033860
20Periodontitis (HP:0000704)3.31242811
21Joint hemorrhage (HP:0005261)3.16288663
22Loss of speech (HP:0002371)3.12713128
23Glomerulonephritis (HP:0000099)3.11562417
24Increased neuronal autofluorescent lipopigment (HP:0002074)3.09958811
25Stomatitis (HP:0010280)3.07170435
26Increased cerebral lipofuscin (HP:0011813)3.05865339
27Vasculitis (HP:0002633)3.05138297
28Urticaria (HP:0001025)3.00903214
29Axonal loss (HP:0003447)2.99428312
30Recurrent viral infections (HP:0004429)2.93807175
31Gingival bleeding (HP:0000225)2.90797851
32Protrusio acetabuli (HP:0003179)2.89554744
33Premature rupture of membranes (HP:0001788)2.89055524
34Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.85262910
35Optic neuritis (HP:0100653)2.85231017
36Retrobulbar optic neuritis (HP:0100654)2.85231017
37Petechiae (HP:0000967)2.84273107
38Pustule (HP:0200039)2.81667540
39Cellulitis (HP:0100658)2.77857217
40Basal ganglia calcification (HP:0002135)2.73665818
41Prolonged partial thromboplastin time (HP:0003645)2.72271275
42Dysostosis multiplex (HP:0000943)2.70307843
43Thrombocytosis (HP:0001894)2.65660636
44Interstitial pulmonary disease (HP:0006530)2.58457056
45Myocardial infarction (HP:0001658)2.58243369
46Abnormal platelet function (HP:0011869)2.56370171
47Impaired platelet aggregation (HP:0003540)2.56370171
48Meningitis (HP:0001287)2.56245502
49Complement deficiency (HP:0004431)2.54783854
50Spondylolisthesis (HP:0003302)2.54408671
51Abnormality of complement system (HP:0005339)2.53190971
52Disinhibition (HP:0000734)2.52031146
53Chronic mucocutaneous candidiasis (HP:0002728)2.46987989
54Recurrent cutaneous fungal infections (HP:0011370)2.46987989
55Chronic otitis media (HP:0000389)2.46583296
56Conjunctival telangiectasia (HP:0000524)2.46558783
57Epistaxis (HP:0000421)2.45177057
58Pulmonary infiltrates (HP:0002113)2.41775256
59Mucopolysacchariduria (HP:0008155)2.41605196
60Urinary glycosaminoglycan excretion (HP:0003541)2.41605196
61Prostate neoplasm (HP:0100787)2.40860803
62Increased IgM level (HP:0003496)2.40015750
63Tetraparesis (HP:0002273)2.39411753
64Peritonitis (HP:0002586)2.38787073
65Nephritis (HP:0000123)2.34419234
66Abnormality of the prostate (HP:0008775)2.34417151
67Purpura (HP:0000979)2.34366166
68Reduced antithrombin III activity (HP:0001976)2.34353421
69Gastrointestinal infarctions (HP:0005244)2.34094836
70Upper motor neuron abnormality (HP:0002127)2.32775321
71Osteomyelitis (HP:0002754)2.28816593
72Recurrent pneumonia (HP:0006532)2.28093321
73Progressive neurologic deterioration (HP:0002344)2.26939374
74Hypergammaglobulinemia (HP:0010702)2.26063213
75Vertebral compression fractures (HP:0002953)2.25802409
76Increased serum ferritin (HP:0003281)2.25752100
77Prolonged neonatal jaundice (HP:0006579)2.25125805
78Arterial thrombosis (HP:0004420)2.24311056
79Abnormality of the common coagulation pathway (HP:0010990)2.23317207
80Abnormality of polysaccharide metabolism (HP:0011012)2.22850176
81Abnormality of glycosaminoglycan metabolism (HP:0004371)2.22850176
82Abnormality of mucopolysaccharide metabolism (HP:0011020)2.22850176
83Spontaneous hematomas (HP:0007420)2.20151972
84Xanthomatosis (HP:0000991)2.18386514
85Hepatosplenomegaly (HP:0001433)2.17325198
86Leukocytosis (HP:0001974)2.17004255
87Poor head control (HP:0002421)2.16707362
88Osteolytic defects of the hand bones (HP:0009699)2.15195070
89Osteolytic defects of the phalanges of the hand (HP:0009771)2.15195070
90Abnormality of iron homeostasis (HP:0011031)2.14346562
91Bruising susceptibility (HP:0000978)2.14097878
92Amyloidosis (HP:0011034)2.12174259
93Cervical subluxation (HP:0003308)2.11088515
94Deep venous thrombosis (HP:0002625)2.10532048
95Recurrent lower respiratory tract infections (HP:0002783)2.10406090
96Hemoptysis (HP:0002105)2.10323655
97Episodic fever (HP:0001954)2.10285151
98Prolonged bleeding time (HP:0003010)2.05132595
99Abnormality of T cell physiology (HP:0011840)2.04771421
100Abnormality of liposaccharide metabolism (HP:0010968)2.04455572
101Abnormality of glycosphingolipid metabolism (HP:0004343)2.04455572
102Abnormality of glycolipid metabolism (HP:0010969)2.04455572
103Hematochezia (HP:0002573)2.01831397
104Ocular albinism (HP:0001107)2.01741120
105Thick nail (HP:0001805)2.00420091
106Abnormality of aromatic amino acid family metabolism (HP:0004338)1.99659089
107Menorrhagia (HP:0000132)1.98914902
108Agnosia (HP:0010524)1.98330364
109Albinism (HP:0001022)1.96674839
110Gangrene (HP:0100758)1.96273874
111Abnormality of monocarboxylic acid metabolism (HP:0010996)1.95871155
112Abnormality of the vasculature of the conjunctiva (HP:0008054)1.95010112
113Keratoconjunctivitis sicca (HP:0001097)1.94772057
114Neoplasm of head and neck (HP:0012288)1.94344601
115Esophageal neoplasm (HP:0100751)1.94344601
116Pathologic fracture (HP:0002756)1.93370448
117Nuclear cataract (HP:0100018)1.93336613
118Asymmetric septal hypertrophy (HP:0001670)1.92119806
119Polycythemia (HP:0001901)1.92033842
120Thrombophlebitis (HP:0004418)1.90779827
121Joint stiffness (HP:0001387)1.87194497
122Abnormality of transition element cation homeostasis (HP:0011030)1.86847194
123Hypertensive crisis (HP:0100735)1.86097598
124Chest pain (HP:0100749)1.84944182
125Mitral stenosis (HP:0001718)1.83037097
126Thoracic kyphosis (HP:0002942)1.76668460
127Mucosal telangiectasiae (HP:0100579)1.76277483
128White forelock (HP:0002211)1.75181054
129Abnormality of the Achilles tendon (HP:0005109)1.74532822
130Distal lower limb muscle weakness (HP:0009053)1.73582149
131Glomerulopathy (HP:0100820)1.73222250
132Aortic dissection (HP:0002647)1.73211494
133Hypertriglyceridemia (HP:0002155)1.71384512
134Bone pain (HP:0002653)1.70244383
135Blue sclerae (HP:0000592)1.69377570
136Hyperlipoproteinemia (HP:0010980)1.69266978
137Dilatation of the ascending aorta (HP:0005111)1.68709087
138Aortic aneurysm (HP:0004942)1.66043747
139Ovoid vertebral bodies (HP:0003300)1.63602187

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K144.10111540
2IRAK43.59700283
3RIPK43.40354301
4BLK3.38561462
5TBK13.21755365
6ERN12.80788750
7IRAK32.77365637
8TYK22.74525279
9KIT2.48796897
10PBK2.44157596
11IKBKE2.32083046
12JAK32.29181026
13TESK22.24445752
14PIM22.23190915
15IKBKB2.14386578
16MAP4K12.07337784
17MYLK1.85311356
18NEK91.81732496
19MAP3K131.78669221
20NME21.75209947
21TAOK31.69893010
22TXK1.64120046
23TEC1.58146434
24ZAP701.56764011
25JAK11.55426651
26SCYL21.54575041
27BTK1.49516670
28CSK1.44969630
29CSF1R1.44221982
30TGFBR21.43506590
31PRPF4B1.38506893
32FLT31.36574444
33CHUK1.35458210
34DDR21.35223049
35MATK1.35104930
36RPS6KA41.32204064
37SYK1.30897345
38ABL21.30084139
39MST1R1.29129128
40STK101.25503974
41TTN1.18901147
42LYN1.16486803
43MAP2K31.14855080
44PIM11.13372724
45TAOK11.11281183
46MAP3K11.07025957
47HCK1.05533364
48ILK0.98666035
49EIF2AK20.98076576
50TRPM70.97920783
51FGFR40.97426395
52JAK20.97398508
53EPHB10.93727229
54LCK0.93501528
55MAP3K60.91788447
56MAP3K120.91369333
57MAP3K50.89685763
58BMX0.89647708
59FES0.88348893
60DAPK30.84517085
61LRRK20.81296386
62LIMK10.80110307
63MAP3K110.79618975
64EPHB20.79371490
65STK40.78370372
66PRKD20.77081733
67PTK2B0.75252891
68PDPK10.74651434
69PAK10.72610145
70PAK20.72183242
71FGR0.71897575
72TNK20.71644146
73KDR0.71143179
74MST40.69216901
75ARAF0.68723577
76MOS0.67719242
77BMPR20.66795530
78ACVR1B0.66145896
79PRKCD0.65897864
80EIF2AK30.65820966
81CLK10.65653849
82IRAK10.65006819
83PDK20.63243408
84GRK50.62101742
85PKN20.59787811
86CDC42BPA0.59576950
87TESK10.59451233
88NLK0.57655426
89MARK30.57642492
90PTK20.57579284
91BCKDK0.57301220
92PAK40.56548641
93PDGFRA0.56240925
94MAP3K100.56061488
95ABL10.56051029
96TGFBR10.55470329
97GSK3A0.53422836
98MAP3K30.52920923
99RIPK10.51892820
100PIK3CG0.50962099
101IRAK20.50014064
102TAOK20.49215543
103FGFR30.48538442
104PDK10.48500197
105EGFR0.47993366
106BMPR1B0.47774366
107ITK0.46652106
108ADRBK10.45049659
109RPS6KA20.44349853
110PRKG20.44026205
111ERBB40.43599813
112SIK10.42690826
113STK30.42320627
114SIK30.42156777
115RPS6KC10.42142475
116RPS6KL10.42142475
117MAPK110.40073918
118ERBB30.40039877
119YES10.39866531
120PTK60.39321602
121CDK60.39160486
122EIF2AK10.37941331
123MAP3K80.37758974
124CAMKK20.36135725
125TRIB30.36122210
126RPS6KA60.35509510
127CDK40.35437020
128GRK70.35346258
129GRK60.35127145
130MAPKAPK20.34542689
131MAPK40.33492664
132EPHA30.33405166

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051503.75509403
2Leishmaniasis_Homo sapiens_hsa051403.34746294
3Legionellosis_Homo sapiens_hsa051342.69613046
4Toll-like receptor signaling pathway_Homo sapiens_hsa046202.57558536
5Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.56164430
6Graft-versus-host disease_Homo sapiens_hsa053322.44937911
7Pertussis_Homo sapiens_hsa051332.40832963
8NF-kappa B signaling pathway_Homo sapiens_hsa040642.32639168
9Malaria_Homo sapiens_hsa051442.20630578
10NOD-like receptor signaling pathway_Homo sapiens_hsa046212.13390220
11RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.12893093
12Osteoclast differentiation_Homo sapiens_hsa043802.04512955
13Tuberculosis_Homo sapiens_hsa051521.94919485
14Complement and coagulation cascades_Homo sapiens_hsa046101.90555062
15Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.87522355
16Allograft rejection_Homo sapiens_hsa053301.86357524
17Measles_Homo sapiens_hsa051621.82954563
18Primary bile acid biosynthesis_Homo sapiens_hsa001201.76900154
19Lysosome_Homo sapiens_hsa041421.67643429
20Rheumatoid arthritis_Homo sapiens_hsa053231.66825622
21Pentose and glucuronate interconversions_Homo sapiens_hsa000401.63239006
22TNF signaling pathway_Homo sapiens_hsa046681.63171149
23Asthma_Homo sapiens_hsa053101.62894019
24African trypanosomiasis_Homo sapiens_hsa051431.59334047
25Influenza A_Homo sapiens_hsa051641.58020504
26Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.56938836
27Other glycan degradation_Homo sapiens_hsa005111.56879445
28Intestinal immune network for IgA production_Homo sapiens_hsa046721.54418788
29Salmonella infection_Homo sapiens_hsa051321.52895660
30Phagosome_Homo sapiens_hsa041451.48526091
31Glycosaminoglycan degradation_Homo sapiens_hsa005311.43810250
32Herpes simplex infection_Homo sapiens_hsa051681.42957592
33Caffeine metabolism_Homo sapiens_hsa002321.40335217
34Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.36922205
35Hematopoietic cell lineage_Homo sapiens_hsa046401.32095080
36Toxoplasmosis_Homo sapiens_hsa051451.31730005
37Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.30727829
38Antigen processing and presentation_Homo sapiens_hsa046121.27652707
39Galactose metabolism_Homo sapiens_hsa000521.26245340
40Bladder cancer_Homo sapiens_hsa052191.25998966
41Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.19760483
42Shigellosis_Homo sapiens_hsa051311.18872011
43Type I diabetes mellitus_Homo sapiens_hsa049401.18477674
44Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.18238512
45Apoptosis_Homo sapiens_hsa042101.16393218
46Sulfur metabolism_Homo sapiens_hsa009201.14754380
47B cell receptor signaling pathway_Homo sapiens_hsa046621.11118390
48Renin-angiotensin system_Homo sapiens_hsa046141.10175917
49Jak-STAT signaling pathway_Homo sapiens_hsa046301.01319323
50Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.00546127
51ECM-receptor interaction_Homo sapiens_hsa045120.99182397
52Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.98345733
53Chemokine signaling pathway_Homo sapiens_hsa040620.94779678
54Histidine metabolism_Homo sapiens_hsa003400.93923198
55Peroxisome_Homo sapiens_hsa041460.93478188
56Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.89497604
57Endocytosis_Homo sapiens_hsa041440.84012996
58Primary immunodeficiency_Homo sapiens_hsa053400.84008457
59Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.83192559
60Hepatitis B_Homo sapiens_hsa051610.82871060
61Amoebiasis_Homo sapiens_hsa051460.80579476
62Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.79491739
63Arginine biosynthesis_Homo sapiens_hsa002200.77627973
64Hepatitis C_Homo sapiens_hsa051600.77538012
65Collecting duct acid secretion_Homo sapiens_hsa049660.75502142
66Focal adhesion_Homo sapiens_hsa045100.75415172
67Leukocyte transendothelial migration_Homo sapiens_hsa046700.75402476
68Sphingolipid metabolism_Homo sapiens_hsa006000.74452247
69Chronic myeloid leukemia_Homo sapiens_hsa052200.74174656
70Folate biosynthesis_Homo sapiens_hsa007900.72942285
71Drug metabolism - other enzymes_Homo sapiens_hsa009830.72273922
72Tryptophan metabolism_Homo sapiens_hsa003800.69419180
73Vibrio cholerae infection_Homo sapiens_hsa051100.69384011
74Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.67860251
75Chemical carcinogenesis_Homo sapiens_hsa052040.67337310
76Systemic lupus erythematosus_Homo sapiens_hsa053220.66351622
77Prion diseases_Homo sapiens_hsa050200.65417550
78Small cell lung cancer_Homo sapiens_hsa052220.64586614
79AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.62839286
80Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.62545035
81Starch and sucrose metabolism_Homo sapiens_hsa005000.62218705
82Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.62025426
83Sphingolipid signaling pathway_Homo sapiens_hsa040710.61900182
84Regulation of actin cytoskeleton_Homo sapiens_hsa048100.60966715
85Pentose phosphate pathway_Homo sapiens_hsa000300.59277638
86Viral myocarditis_Homo sapiens_hsa054160.56053467
87Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.55493632
88Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.54246253
89Selenocompound metabolism_Homo sapiens_hsa004500.53296367
90Acute myeloid leukemia_Homo sapiens_hsa052210.52612305
91Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.52530540
92Steroid hormone biosynthesis_Homo sapiens_hsa001400.52006079
93ABC transporters_Homo sapiens_hsa020100.50714709
94VEGF signaling pathway_Homo sapiens_hsa043700.50627054
95Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.50482327
96Platelet activation_Homo sapiens_hsa046110.49733166
97Proteasome_Homo sapiens_hsa030500.49405742
98PPAR signaling pathway_Homo sapiens_hsa033200.49266311
99Retinol metabolism_Homo sapiens_hsa008300.47854452
100Adipocytokine signaling pathway_Homo sapiens_hsa049200.46744818
101beta-Alanine metabolism_Homo sapiens_hsa004100.45690402
102Non-small cell lung cancer_Homo sapiens_hsa052230.45297099
103Vitamin digestion and absorption_Homo sapiens_hsa049770.44666250
104Fatty acid degradation_Homo sapiens_hsa000710.44522458
105Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.43867136
106SNARE interactions in vesicular transport_Homo sapiens_hsa041300.41599218
107Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.41243215
108Sulfur relay system_Homo sapiens_hsa041220.41241726
109Autoimmune thyroid disease_Homo sapiens_hsa053200.41115225
110Proteoglycans in cancer_Homo sapiens_hsa052050.40228235
111Viral carcinogenesis_Homo sapiens_hsa052030.36570616
112Fructose and mannose metabolism_Homo sapiens_hsa000510.36472516
113Phospholipase D signaling pathway_Homo sapiens_hsa040720.35031032
114Transcriptional misregulation in cancer_Homo sapiens_hsa052020.34106812
115Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.33332281
116Neurotrophin signaling pathway_Homo sapiens_hsa047220.32631558
117Arachidonic acid metabolism_Homo sapiens_hsa005900.31979159
118HTLV-I infection_Homo sapiens_hsa051660.31949638
119Epstein-Barr virus infection_Homo sapiens_hsa051690.31430237
120Glutathione metabolism_Homo sapiens_hsa004800.30890295
121Steroid biosynthesis_Homo sapiens_hsa001000.30248581
122N-Glycan biosynthesis_Homo sapiens_hsa005100.30021137
123Renal cell carcinoma_Homo sapiens_hsa052110.27656132
124HIF-1 signaling pathway_Homo sapiens_hsa040660.27607380
125Phenylalanine metabolism_Homo sapiens_hsa003600.26862599
126One carbon pool by folate_Homo sapiens_hsa006700.25965691
127Pancreatic cancer_Homo sapiens_hsa052120.25209942

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