QSER1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic sister chromatid cohesion (GO:0007064)4.56463187
2paraxial mesoderm development (GO:0048339)4.46131049
3nuclear pore complex assembly (GO:0051292)4.19290282
4pre-miRNA processing (GO:0031054)4.16285078
5nuclear pore organization (GO:0006999)4.15201354
6kinetochore organization (GO:0051383)4.14552111
7regulation of RNA export from nucleus (GO:0046831)4.11005772
8chromatin remodeling at centromere (GO:0031055)3.99891547
9embryonic process involved in female pregnancy (GO:0060136)3.98955579
10regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.97708486
11positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.93155111
12positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.93155111
13positive regulation of mitotic sister chromatid separation (GO:1901970)3.93155111
14regulation of centriole replication (GO:0046599)3.89027366
15regulation of sister chromatid cohesion (GO:0007063)3.86877432
16replication fork processing (GO:0031297)3.82634408
17establishment of integrated proviral latency (GO:0075713)3.81911166
18dosage compensation (GO:0007549)3.74150416
19regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.71018179
20DNA replication checkpoint (GO:0000076)3.68990813
21CENP-A containing nucleosome assembly (GO:0034080)3.68032616
22kinetochore assembly (GO:0051382)3.67020766
23meiotic chromosome segregation (GO:0045132)3.62850590
24DNA topological change (GO:0006265)3.54723312
25sister chromatid segregation (GO:0000819)3.48890016
26maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.47637678
27regulation of helicase activity (GO:0051095)3.40299149
28establishment of apical/basal cell polarity (GO:0035089)3.35417616
29somatic diversification of immune receptors via somatic mutation (GO:0002566)3.31589667
30somatic hypermutation of immunoglobulin genes (GO:0016446)3.31589667
31histone exchange (GO:0043486)3.31148036
32DNA unwinding involved in DNA replication (GO:0006268)3.30757626
33mitotic sister chromatid segregation (GO:0000070)3.26874337
34mitotic nuclear envelope disassembly (GO:0007077)3.26447918
35proline biosynthetic process (GO:0006561)3.26411574
36negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.23720650
37negative regulation of mitotic sister chromatid separation (GO:2000816)3.20765069
38negative regulation of sister chromatid segregation (GO:0033046)3.20765069
39negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.20765069
40negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.20765069
41negative regulation of mitotic sister chromatid segregation (GO:0033048)3.20765069
42regulation of centrosome duplication (GO:0010824)3.20592845
43spindle checkpoint (GO:0031577)3.19119226
44regulation of DNA endoreduplication (GO:0032875)3.18911236
45negative regulation of translation, ncRNA-mediated (GO:0040033)3.18575460
46regulation of translation, ncRNA-mediated (GO:0045974)3.18575460
47negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.18575460
48regulation of chromosome segregation (GO:0051983)3.18329563
49protein localization to kinetochore (GO:0034501)3.15925209
50mitotic chromosome condensation (GO:0007076)3.13612231
51DNA replication-independent nucleosome organization (GO:0034724)3.13410852
52DNA replication-independent nucleosome assembly (GO:0006336)3.13410852
53positive regulation of chromosome segregation (GO:0051984)3.11260193
54DNA strand elongation involved in DNA replication (GO:0006271)3.10891235
55mitotic spindle checkpoint (GO:0071174)3.08069254
56embryonic foregut morphogenesis (GO:0048617)3.05996000
57negative regulation of histone methylation (GO:0031061)3.05953682
58hippo signaling (GO:0035329)3.04298091
59regulation of posttranscriptional gene silencing (GO:0060147)3.03591295
60regulation of gene silencing by miRNA (GO:0060964)3.03591295
61regulation of gene silencing by RNA (GO:0060966)3.03591295
62membrane disassembly (GO:0030397)3.03419307
63nuclear envelope disassembly (GO:0051081)3.03419307
64double-strand break repair via nonhomologous end joining (GO:0006303)3.03144806
65non-recombinational repair (GO:0000726)3.03144806
66metaphase plate congression (GO:0051310)3.02574512
67regulation of nucleobase-containing compound transport (GO:0032239)3.01323217
68cytoplasmic mRNA processing body assembly (GO:0033962)3.00674640
69regulation of histone H3-K9 methylation (GO:0051570)2.99304719
70regulation of translational fidelity (GO:0006450)2.99247004
71heterochromatin organization (GO:0070828)2.98888779
72DNA strand elongation (GO:0022616)2.98825675
73DNA strand renaturation (GO:0000733)2.98484693
74negative regulation of mRNA processing (GO:0050686)2.97951560
75mitotic metaphase plate congression (GO:0007080)2.95931885
76ATP-dependent chromatin remodeling (GO:0043044)2.95902056
77regulation of stem cell maintenance (GO:2000036)2.95739398
78DNA geometric change (GO:0032392)2.92927966
79DNA duplex unwinding (GO:0032508)2.92297639
80mitotic spindle assembly checkpoint (GO:0007094)2.92200054
81pore complex assembly (GO:0046931)2.90361265
82regulation of double-strand break repair (GO:2000779)2.90282946
83chromatin assembly (GO:0031497)2.87634192
84negative regulation of RNA splicing (GO:0033119)2.87220613
85spindle assembly checkpoint (GO:0071173)2.86569617
86regulation of mitotic spindle checkpoint (GO:1903504)2.86169080
87regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.86169080
88mitotic G2/M transition checkpoint (GO:0044818)2.86166707
89protein complex localization (GO:0031503)2.85456912
90spliceosomal tri-snRNP complex assembly (GO:0000244)2.85061529
91convergent extension (GO:0060026)2.83484322
92positive regulation of SMAD protein import into nucleus (GO:0060391)2.82892229
93glucocorticoid receptor signaling pathway (GO:0042921)2.82597315
94sister chromatid cohesion (GO:0007062)2.82452943
95lateral sprouting from an epithelium (GO:0060601)2.82358889
96planar cell polarity pathway involved in neural tube closure (GO:0090179)2.82195647
97regulation of spindle organization (GO:0090224)2.80362253
98negative regulation of DNA-dependent DNA replication (GO:2000104)2.80208833
99establishment or maintenance of monopolar cell polarity (GO:0061339)2.80153576
100establishment of monopolar cell polarity (GO:0061162)2.80153576
101transcription from mitochondrial promoter (GO:0006390)2.79597463
102regulation of mitotic spindle organization (GO:0060236)2.79384760
103embryonic camera-type eye development (GO:0031076)2.79200664
104regulation of integrin activation (GO:0033623)2.78253382
105notochord development (GO:0030903)2.76275757
106telomere maintenance via telomerase (GO:0007004)2.74686072
107chromatin assembly or disassembly (GO:0006333)2.74564559
108establishment of chromosome localization (GO:0051303)2.73867463
109embryonic placenta development (GO:0001892)2.73603748
110negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)2.72857046
111negative regulation of mRNA metabolic process (GO:1903312)2.71572808
112mRNA cleavage (GO:0006379)2.71040779
113regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.70601795
114negative regulation of DNA repair (GO:0045738)2.70239330
115anatomical structure regression (GO:0060033)2.70077305
116trophectodermal cell differentiation (GO:0001829)2.70010535
117response to X-ray (GO:0010165)2.69565812
118regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.68805131
119positive regulation by host of viral transcription (GO:0043923)2.68067466
120protein localization to chromosome (GO:0034502)2.65490830
121regulation of DNA damage checkpoint (GO:2000001)2.63758302
122negative regulation of chondrocyte differentiation (GO:0032331)2.63231503
123anterior/posterior axis specification, embryo (GO:0008595)2.63198911
124base-excision repair (GO:0006284)2.62978153
125mRNA stabilization (GO:0048255)2.62710322
126RNA stabilization (GO:0043489)2.62710322
127protein localization to chromosome, centromeric region (GO:0071459)2.62708453
128regulation of mitotic metaphase/anaphase transition (GO:0030071)2.61153493
129chromosome condensation (GO:0030261)2.60821064
130negative regulation of chromosome segregation (GO:0051985)2.60256648
131chromosome segregation (GO:0007059)2.59723558
132mRNA transport (GO:0051028)2.59220282
133face development (GO:0060324)2.58936357
134telomere maintenance via semi-conservative replication (GO:0032201)2.58704048
135histone mRNA catabolic process (GO:0071044)2.58575076
136NLS-bearing protein import into nucleus (GO:0006607)2.58185425
137DNA double-strand break processing (GO:0000729)2.57831766
138mitotic recombination (GO:0006312)2.57497467
139cellular protein complex localization (GO:0034629)2.57085152
140histone-serine phosphorylation (GO:0035404)2.56820298
141DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.55850441
142viral mRNA export from host cell nucleus (GO:0046784)2.55591337
143regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.55459154
144regulation of centrosome cycle (GO:0046605)2.55045015
145negative regulation of cell cycle arrest (GO:0071157)2.54744117
146negative regulation of mitosis (GO:0045839)2.53601357
147DNA conformation change (GO:0071103)2.52028380
148nuclear envelope organization (GO:0006998)2.51852368
149establishment of viral latency (GO:0019043)2.51730579
150regulation of SMAD protein import into nucleus (GO:0060390)2.50825133
151regulation of mitotic sister chromatid separation (GO:0010965)2.50580158
152regulation of mitotic sister chromatid segregation (GO:0033047)2.50580158
153regulation of sister chromatid segregation (GO:0033045)2.50580158

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.68919901
2* FOXM1_23109430_ChIP-Seq_U2OS_Human5.40991235
3SALL1_21062744_ChIP-ChIP_HESCs_Human3.65937115
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.65902645
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.37120652
6EGR1_19374776_ChIP-ChIP_THP-1_Human3.16204314
7* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.03295677
8MYC_18555785_ChIP-Seq_MESCs_Mouse2.80948017
9TP63_19390658_ChIP-ChIP_HaCaT_Human2.78917709
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.55839369
11ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.54988775
12RBPJ_22232070_ChIP-Seq_NCS_Mouse2.46132724
13NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.41500993
14KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.35435192
15KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.35435192
16KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.35435192
17STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.34783407
18AR_21909140_ChIP-Seq_LNCAP_Human2.33761953
19HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.29953062
20SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.22853953
21MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.18312278
22* E2F1_21310950_ChIP-Seq_MCF-7_Human2.18186220
23ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.14797023
24FUS_26573619_Chip-Seq_HEK293_Human2.09225593
25SALL4_18804426_ChIP-ChIP_MESCs_Mouse2.08508604
26MYC_19079543_ChIP-ChIP_MESCs_Mouse2.04451602
27POU5F1_16153702_ChIP-ChIP_HESCs_Human2.02161897
28CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.91349236
29SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.88595724
30ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.83728305
31MYC_19030024_ChIP-ChIP_MESCs_Mouse1.82988491
32NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.82378419
33* MYC_22102868_ChIP-Seq_BL_Human1.80331229
34RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.79642266
35* EWS_26573619_Chip-Seq_HEK293_Human1.76528615
36ELK1_19687146_ChIP-ChIP_HELA_Human1.75925150
37ESR1_15608294_ChIP-ChIP_MCF-7_Human1.75782232
38NANOG_21062744_ChIP-ChIP_HESCs_Human1.75469147
39NELFA_20434984_ChIP-Seq_ESCs_Mouse1.71571206
40SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.66495641
41POU3F2_20337985_ChIP-ChIP_501MEL_Human1.64204211
42TCF3_18692474_ChIP-Seq_MESCs_Mouse1.64064408
43SOX2_18555785_ChIP-Seq_MESCs_Mouse1.62836358
44TCF3_18692474_ChIP-Seq_MEFs_Mouse1.60981174
45MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.60433099
46KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.60231202
47MYCN_18555785_ChIP-Seq_MESCs_Mouse1.59461084
48SOX2_16153702_ChIP-ChIP_HESCs_Human1.58529506
49NANOG_16153702_ChIP-ChIP_HESCs_Human1.54190559
50POU5F1_16518401_ChIP-PET_MESCs_Mouse1.53541519
51POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.53363551
52WT1_19549856_ChIP-ChIP_CCG9911_Human1.52436678
53DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.45733120
54* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.39968274
55GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.38055031
56TAF15_26573619_Chip-Seq_HEK293_Human1.36830443
57PADI4_21655091_ChIP-ChIP_MCF-7_Human1.34641793
58EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.32354814
59DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.32273979
60YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.31747989
61P300_19829295_ChIP-Seq_ESCs_Human1.31417538
62HIF1A_21447827_ChIP-Seq_MCF-7_Human1.29661995
63ZFP281_27345836_Chip-Seq_ESCs_Mouse1.29390785
64TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.29161338
65SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.28072506
66NANOG_18555785_ChIP-Seq_MESCs_Mouse1.27652096
67MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.27605479
68NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.26466806
69NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.25120038
70PKCTHETA_26484144_Chip-Seq_BREAST_Human1.24643644
71SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.24341632
72* CHD1_26751641_Chip-Seq_LNCaP_Human1.23674028
73IGF1R_20145208_ChIP-Seq_DFB_Human1.23157072
74ZFX_18555785_ChIP-Seq_MESCs_Mouse1.22866858
75STAT3_1855785_ChIP-Seq_MESCs_Mouse1.22715779
76TP63_17297297_ChIP-ChIP_HaCaT_Human1.20429223
77GBX2_23144817_ChIP-Seq_PC3_Human1.20332651
78MYC_18358816_ChIP-ChIP_MESCs_Mouse1.19100598
79SOX9_26525672_Chip-Seq_HEART_Mouse1.19062082
80CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.17021379
81CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.17020918
82DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.16985244
83KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.16225686
84AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.15864347
85PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.15328835
86* NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.14878526
87CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.13488310
88KLF4_18555785_ChIP-Seq_MESCs_Mouse1.13336958
89POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.12222376
90VDR_21846776_ChIP-Seq_THP-1_Human1.12217387
91KDM5A_27292631_Chip-Seq_BREAST_Human1.11534704
92EST1_17652178_ChIP-ChIP_JURKAT_Human1.11189684
93POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.10150219
94SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.08521728
95ZFP57_27257070_Chip-Seq_ESCs_Mouse1.08342188
96EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.07565912
97TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.05847404
98TCF7_22412390_ChIP-Seq_EML_Mouse1.05646435
99PIAS1_25552417_ChIP-Seq_VCAP_Human1.05597502
100CREB1_15753290_ChIP-ChIP_HEK293T_Human1.05533123
101MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.05411160
102EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.04219188
103MYC_18940864_ChIP-ChIP_HL60_Human1.04214083
104POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.02643193
105* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.02396978
106BRD4_25478319_ChIP-Seq_HGPS_Human1.02391804
107RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.01960818
108ZNF263_19887448_ChIP-Seq_K562_Human1.01419466
109STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.01063156
110TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.00884518
111POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.00365215
112TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00365215
113ISL1_27105846_Chip-Seq_CPCs_Mouse0.99673018
114ZFP281_18757296_ChIP-ChIP_E14_Mouse0.99635771
115SMAD3_21741376_ChIP-Seq_EPCs_Human0.99177967
116TTF2_22483619_ChIP-Seq_HELA_Human0.98975097
117PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.98059925
118TBX3_20139965_ChIP-Seq_ESCs_Mouse0.96709686
119ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.95377915
120XRN2_22483619_ChIP-Seq_HELA_Human0.95237487
121KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.95078128
122FLI1_27457419_Chip-Seq_LIVER_Mouse0.95032344
123TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.94972148
124GATA4_21415370_ChIP-Seq_HL-1_Mouse0.94753827
125PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.94436161
126E2F1_18555785_ChIP-Seq_MESCs_Mouse0.94430100
127FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.94392122
128TBX3_20139965_ChIP-Seq_MESCs_Mouse0.94145320
129OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.93258406
130KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.92941489
131CLOCK_20551151_ChIP-Seq_293T_Human0.92347205
132* NFIB_24661679_ChIP-Seq_LUNG_Mouse0.92031612
133CTBP2_25329375_ChIP-Seq_LNCAP_Human0.91035263
134CIITA_25753668_ChIP-Seq_RAJI_Human0.90575838
135SALL4_18804426_ChIP-ChIP_XEN_Mouse0.90429366
136FOXM1_26456572_ChIP-Seq_MCF-7_Human0.90270044
137* SMAD4_21799915_ChIP-Seq_A2780_Human0.90036801
138YAP1_20516196_ChIP-Seq_MESCs_Mouse0.89108674
139KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.89062422
140TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.88855933
141ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.88447542
142CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.87601163
143STAT3_23295773_ChIP-Seq_U87_Human0.87244887
144* FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.87052360
145GATA1_26923725_Chip-Seq_HPCs_Mouse0.86668489
146SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.85827011
147SOX17_20123909_ChIP-Seq_XEN_Mouse0.85499527
148CTBP1_25329375_ChIP-Seq_LNCAP_Human0.82856825
149* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.81750901
150ZNF274_21170338_ChIP-Seq_K562_Hela0.81308621
151TOP2B_26459242_ChIP-Seq_MCF-7_Human0.79943332
152SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.79266742
153GABP_17652178_ChIP-ChIP_JURKAT_Human0.78870952
154TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.77508787

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010030_abnormal_orbit_morphology3.52630493
2MP0008057_abnormal_DNA_replication3.43246569
3MP0009697_abnormal_copulation2.67998867
4MP0010094_abnormal_chromosome_stability2.61487269
5MP0010352_gastrointestinal_tract_polyps2.33029701
6MP0003890_abnormal_embryonic-extraembry2.21169718
7MP0003705_abnormal_hypodermis_morpholog2.20822019
8MP0006292_abnormal_olfactory_placode2.08403296
9MP0003111_abnormal_nucleus_morphology2.06992543
10MP0005076_abnormal_cell_differentiation2.06542581
11MP0003567_abnormal_fetal_cardiomyocyte2.05077954
12MP0003077_abnormal_cell_cycle2.00456541
13MP0009053_abnormal_anal_canal1.97256765
14MP0002009_preneoplasia1.96177606
15MP0004957_abnormal_blastocyst_morpholog1.96157735
16MP0009278_abnormal_bone_marrow1.89208458
17MP0004233_abnormal_muscle_weight1.86314193
18MP0003693_abnormal_embryo_hatching1.84323869
19MP0001293_anophthalmia1.79404121
20MP0004197_abnormal_fetal_growth/weight/1.76651804
21MP0002084_abnormal_developmental_patter1.75899757
22MP0005380_embryogenesis_phenotype1.66677574
23MP0001672_abnormal_embryogenesis/_devel1.66677574
24MP0002249_abnormal_larynx_morphology1.66351138
25MP0002085_abnormal_embryonic_tissue1.63889288
26MP0008877_abnormal_DNA_methylation1.61773781
27MP0002086_abnormal_extraembryonic_tissu1.56484538
28MP0003984_embryonic_growth_retardation1.56397881
29MP0002088_abnormal_embryonic_growth/wei1.55114903
30MP0001697_abnormal_embryo_size1.54553055
31MP0000350_abnormal_cell_proliferation1.52278563
32MP0003935_abnormal_craniofacial_develop1.51530926
33MP0003941_abnormal_skin_development1.51248452
34MP0010307_abnormal_tumor_latency1.49840455
35MP0003121_genomic_imprinting1.48828629
36MP0008058_abnormal_DNA_repair1.47069547
37MP0001730_embryonic_growth_arrest1.45924569
38MP0000537_abnormal_urethra_morphology1.45795127
39MP0008007_abnormal_cellular_replicative1.45411320
40MP0003755_abnormal_palate_morphology1.45278870
41MP0003119_abnormal_digestive_system1.45001845
42MP0003937_abnormal_limbs/digits/tail_de1.44690445
43MP0003123_paternal_imprinting1.44493017
44MP0001188_hyperpigmentation1.42580894
45MP0003385_abnormal_body_wall1.42287264
46MP0003942_abnormal_urinary_system1.37687775
47MP0000733_abnormal_muscle_development1.37090173
48MP0008932_abnormal_embryonic_tissue1.35666064
49MP0001299_abnormal_eye_distance/1.35460497
50MP0003136_yellow_coat_color1.33689935
51MP0002938_white_spotting1.32902621
52MP0000432_abnormal_head_morphology1.32190711
53MP0002932_abnormal_joint_morphology1.30770629
54MP0003861_abnormal_nervous_system1.26173510
55MP0003283_abnormal_digestive_organ1.26044486
56MP0000778_abnormal_nervous_system1.25497697
57MP0000049_abnormal_middle_ear1.24809655
58MP0000566_synostosis1.23402903
59MP0000428_abnormal_craniofacial_morphol1.23159114
60MP0002282_abnormal_trachea_morphology1.21452007
61MP0000516_abnormal_urinary_system1.21029003
62MP0005367_renal/urinary_system_phenotyp1.21029003
63MP0010630_abnormal_cardiac_muscle1.20145947
64MP0009250_abnormal_appendicular_skeleto1.17796242
65MP0009703_decreased_birth_body1.15921245
66MP0000762_abnormal_tongue_morphology1.15106360
67MP0003718_maternal_effect1.14040069
68MP0002396_abnormal_hematopoietic_system1.13842171
69MP0004133_heterotaxia1.13822269
70MP0002116_abnormal_craniofacial_bone1.13290137
71MP0005248_abnormal_Harderian_gland1.12433633
72MP0005187_abnormal_penis_morphology1.11953490
73MP0002111_abnormal_tail_morphology1.11576308
74MP0002697_abnormal_eye_size1.11081873
75MP0003115_abnormal_respiratory_system1.11005538
76MP0001177_atelectasis1.10996388
77MP0004264_abnormal_extraembryonic_tissu1.10553832
78MP0002925_abnormal_cardiovascular_devel1.08584011
79MP0002080_prenatal_lethality1.07805838
80MP0005171_absent_coat_pigmentation1.07181329
81MP0004808_abnormal_hematopoietic_stem1.06787696
82MP0005503_abnormal_tendon_morphology1.04657018
83MP0000647_abnormal_sebaceous_gland1.03318961
84MP0001286_abnormal_eye_development1.02945079
85MP0005397_hematopoietic_system_phenotyp1.02936789
86MP0001545_abnormal_hematopoietic_system1.02936789
87MP0006072_abnormal_retinal_apoptosis1.02140074
88MP0009672_abnormal_birth_weight0.99616538
89MP0002108_abnormal_muscle_morphology0.99387936
90MP0002092_abnormal_eye_morphology0.98739727
91MP0000383_abnormal_hair_follicle0.95933427
92MP0005508_abnormal_skeleton_morphology0.95302435
93MP0000266_abnormal_heart_morphology0.95122534
94MP0003786_premature_aging0.94344698
95MP0002114_abnormal_axial_skeleton0.94108744
96MP0003566_abnormal_cell_adhesion0.93009032
97MP0004272_abnormal_basement_membrane0.92479088
98MP0010678_abnormal_skin_adnexa0.91864654
99MP0008438_abnormal_cutaneous_collagen0.91202186
100MP0002751_abnormal_autonomic_nervous0.90660281
101MP0004087_abnormal_muscle_fiber0.89599211
102MP0002081_perinatal_lethality0.89209967
103MP0003787_abnormal_imprinting0.89045641
104MP0002233_abnormal_nose_morphology0.89040309
105MP0000534_abnormal_ureter_morphology0.88442217
106MP0002109_abnormal_limb_morphology0.87806953
107MP0000579_abnormal_nail_morphology0.87191897
108MP0003943_abnormal_hepatobiliary_system0.85388629
109MP0003828_pulmonary_edema0.84686362
110MP0000631_abnormal_neuroendocrine_gland0.83576657
111MP0002877_abnormal_melanocyte_morpholog0.82712009
112MP0002102_abnormal_ear_morphology0.82450538
113MP0001915_intracranial_hemorrhage0.81965938
114MP0000569_abnormal_digit_pigmentation0.80622421
115MP0005391_vision/eye_phenotype0.80114065
116MP0002060_abnormal_skin_morphology0.79960625
117MP0001849_ear_inflammation0.79861121
118MP0002269_muscular_atrophy0.79349620
119MP0000462_abnormal_digestive_system0.78490542
120MP0001340_abnormal_eyelid_morphology0.77821967
121MP0008995_early_reproductive_senescence0.77203285
122MP0005623_abnormal_meninges_morphology0.76983451
123MP0010368_abnormal_lymphatic_system0.76765717
124MP0005257_abnormal_intraocular_pressure0.73801748
125MP0002210_abnormal_sex_determination0.71490473
126MP0001346_abnormal_lacrimal_gland0.71019747
127MP0004185_abnormal_adipocyte_glucose0.70856687
128MP0002184_abnormal_innervation0.70740193
129MP0003315_abnormal_perineum_morphology0.69625782
130MP0010234_abnormal_vibrissa_follicle0.67252986
131MP0002090_abnormal_vision0.66597450
132MP0008789_abnormal_olfactory_epithelium0.65254338
133MP0002254_reproductive_system_inflammat0.64499403

Predicted human phenotypes

RankGene SetZ-score
1Volvulus (HP:0002580)3.93436732
2Short 4th metacarpal (HP:0010044)3.70429564
3Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.70429564
4Facial hemangioma (HP:0000329)3.20241652
5Hepatoblastoma (HP:0002884)3.00487320
6Rib fusion (HP:0000902)2.94770506
7Abnormality of the 4th metacarpal (HP:0010012)2.91303863
8Cortical dysplasia (HP:0002539)2.90157676
9Abnormality of chromosome stability (HP:0003220)2.80941236
10Abnormal lung lobation (HP:0002101)2.79961037
11Colon cancer (HP:0003003)2.69219099
12Meckel diverticulum (HP:0002245)2.63904373
13Rectal prolapse (HP:0002035)2.62945097
14Aplasia/Hypoplasia of the uvula (HP:0010293)2.60316785
15Selective tooth agenesis (HP:0001592)2.49289403
16Abnormality of the ileum (HP:0001549)2.47601077
17Neoplasm of the oral cavity (HP:0100649)2.45393742
18Increased number of teeth (HP:0011069)2.41461071
19Long eyelashes (HP:0000527)2.40364746
20Abnormal number of incisors (HP:0011064)2.39170781
21Short humerus (HP:0005792)2.38448534
22Abnormality of the nasal septum (HP:0000419)2.38059694
23Broad thumb (HP:0011304)2.37369485
24Small intestinal stenosis (HP:0012848)2.33672074
25Duodenal stenosis (HP:0100867)2.33672074
26Medulloblastoma (HP:0002885)2.32625486
27Coronal craniosynostosis (HP:0004440)2.31729515
28Hypoplastic ischia (HP:0003175)2.31561003
29Increased nuchal translucency (HP:0010880)2.28295743
30Trigonocephaly (HP:0000243)2.28277779
31Birth length less than 3rd percentile (HP:0003561)2.27463474
32Astrocytoma (HP:0009592)2.27231657
33Abnormality of the astrocytes (HP:0100707)2.27231657
34Neoplasm of the adrenal cortex (HP:0100641)2.25317631
35Rhabdomyosarcoma (HP:0002859)2.25215487
36Shallow orbits (HP:0000586)2.24103646
37Abnormality of the duodenum (HP:0002246)2.23069722
38Esophageal atresia (HP:0002032)2.22378338
39Aplasia/hypoplasia of the humerus (HP:0006507)2.22298797
40Abnormality of the preputium (HP:0100587)2.22036216
41Intestinal fistula (HP:0100819)2.22021965
42Hypochromic microcytic anemia (HP:0004840)2.20615922
43Abnormality of the labia minora (HP:0012880)2.17574032
44Ectopic kidney (HP:0000086)2.15682814
45Lip pit (HP:0100267)2.14573830
46Midline defect of the nose (HP:0004122)2.14272480
47Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.14112502
48Septo-optic dysplasia (HP:0100842)2.14062340
49Glioma (HP:0009733)2.13460116
50Rectovaginal fistula (HP:0000143)2.10903351
51Rectal fistula (HP:0100590)2.10903351
52Urethral obstruction (HP:0000796)2.10015273
53Renal duplication (HP:0000075)2.09451221
54Abnormality of the fingertips (HP:0001211)2.07951863
55Embryonal neoplasm (HP:0002898)2.06176997
56Broad toe (HP:0001837)2.05564942
57Chromsome breakage (HP:0040012)2.04482928
58Short 5th finger (HP:0009237)2.04009059
59Aqueductal stenosis (HP:0002410)2.03978237
60Ependymoma (HP:0002888)2.02487295
61Deviation of the thumb (HP:0009603)2.02426133
62Neoplasm of striated muscle (HP:0009728)2.01620539
63Bifid tongue (HP:0010297)2.01334099
64Abnormality of the ischium (HP:0003174)1.98747507
65Cerebral aneurysm (HP:0004944)1.96996641
66Supernumerary ribs (HP:0005815)1.95654243
67Proximal placement of thumb (HP:0009623)1.95290205
68Skull defect (HP:0001362)1.94448718
69Abnormality of abdominal situs (HP:0011620)1.94226710
70Abdominal situs inversus (HP:0003363)1.94226710
71Abnormality of the carotid arteries (HP:0005344)1.93072634
72Patellar aplasia (HP:0006443)1.93041838
73Facial cleft (HP:0002006)1.93041537
74Turricephaly (HP:0000262)1.92344129
75Broad phalanges of the hand (HP:0009768)1.90890388
76Ulnar bowing (HP:0003031)1.90839584
77Bilateral microphthalmos (HP:0007633)1.89664636
78Vertebral arch anomaly (HP:0008438)1.88321276
79Broad hallux (HP:0010055)1.87925330
80Intestinal atresia (HP:0011100)1.87576118
81Absent eyebrow (HP:0002223)1.87485464
82Shawl scrotum (HP:0000049)1.87125117
83Short phalanx of the thumb (HP:0009660)1.86835935
84Deep philtrum (HP:0002002)1.85515704
85Triphalangeal thumb (HP:0001199)1.84344837
86Abnormality of the septum pellucidum (HP:0007375)1.84095177
87Syringomyelia (HP:0003396)1.83731791
88Spinal cord lesions (HP:0100561)1.83731791
89Gastrointestinal atresia (HP:0002589)1.82904031
90Short 1st metacarpal (HP:0010034)1.82448834
91Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.82448834
92Papillary thyroid carcinoma (HP:0002895)1.81726949
93Absent radius (HP:0003974)1.81677081
94Atresia of the external auditory canal (HP:0000413)1.81491349
95Sloping forehead (HP:0000340)1.81443347
96Aplasia/Hypoplasia of the patella (HP:0006498)1.81108931
97Broad finger (HP:0001500)1.80621639
98Hypoplastic labia majora (HP:0000059)1.79471142
99Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.79081201
100Broad palm (HP:0001169)1.78582758
101Acute myeloid leukemia (HP:0004808)1.78270983
102Cutaneous finger syndactyly (HP:0010554)1.78080318
103Protrusio acetabuli (HP:0003179)1.77087122
104Chorioretinal atrophy (HP:0000533)1.76958684
105Myelomeningocele (HP:0002475)1.75480873
106Diastasis recti (HP:0001540)1.71979048
107Cutaneous syndactyly (HP:0012725)1.71732125
108Duplication of thumb phalanx (HP:0009942)1.71168426
109Broad phalanx (HP:0006009)1.70984001
110Narrow palate (HP:0000189)1.70876232
111Supernumerary bones of the axial skeleton (HP:0009144)1.70689521
112Preaxial foot polydactyly (HP:0001841)1.70293440
113Abnormality of the aortic arch (HP:0012303)1.69974600
114Gastrointestinal carcinoma (HP:0002672)1.68627077
115Malignant gastrointestinal tract tumors (HP:0006749)1.68627077
116Increased connective tissue (HP:0009025)1.68587780
117Macroorchidism (HP:0000053)1.68585073
118Nephroblastoma (Wilms tumor) (HP:0002667)1.68529069
119Uterine leiomyosarcoma (HP:0002891)1.67661908
120Leiomyosarcoma (HP:0100243)1.67661908
121Abnormality of the labia majora (HP:0012881)1.67619021
122Thyroid carcinoma (HP:0002890)1.67601444
123Neoplasm of the colon (HP:0100273)1.67396388
124Chromosomal breakage induced by crosslinking agents (HP:0003221)1.66660693
125Microglossia (HP:0000171)1.66322187
126Aplasia/Hypoplasia of the sternum (HP:0006714)1.66198825
127Anophthalmia (HP:0000528)1.66047570
128Vaginal fistula (HP:0004320)1.65997686
129Concave nail (HP:0001598)1.65870363
130Aplasia involving forearm bones (HP:0009822)1.65695905
131Absent forearm bone (HP:0003953)1.65695905
132Missing ribs (HP:0000921)1.65632267
133Mesomelia (HP:0003027)1.65480699
134High anterior hairline (HP:0009890)1.64474745
135Transitional cell carcinoma of the bladder (HP:0006740)1.64206528
136Absent septum pellucidum (HP:0001331)1.64148748
137Cafe-au-lait spot (HP:0000957)1.63358691
138Omphalocele (HP:0001539)1.62898136
139Broad long bones (HP:0005622)1.62110040
140Cystic hygroma (HP:0000476)1.62011324
141Abnormality of the parietal bone (HP:0002696)1.60939112
142Choanal atresia (HP:0000453)1.59656943
143Skin tags (HP:0010609)1.59296315
144Abnormality of the distal phalanx of the thumb (HP:0009617)1.59073333
145Choanal stenosis (HP:0000452)1.59030613
146Hamartoma (HP:0010566)1.58890979
147Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.58752726
148Embryonal renal neoplasm (HP:0011794)1.58490518
149Myelodysplasia (HP:0002863)1.58485816
150Biliary tract neoplasm (HP:0100574)1.57529421
151Anal stenosis (HP:0002025)1.54232433
152Abnormality of chromosome segregation (HP:0002916)1.53726494
153Uterine neoplasm (HP:0010784)1.52785802
154Overlapping toe (HP:0001845)1.52319932
155Vertebral clefting (HP:0008428)1.52075350
156Obsessive-compulsive behavior (HP:0000722)1.51895200
157Absent eyelashes (HP:0000561)1.50751182
158Spastic diplegia (HP:0001264)1.49752648
1592-3 toe syndactyly (HP:0004691)1.49381104
160Abnormal hair whorl (HP:0010721)1.48786609
161Partial agenesis of the corpus callosum (HP:0001338)1.48729524
162Bladder carcinoma (HP:0002862)1.47536472

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK123.62419073
2LATS13.33551087
3CDC73.22938999
4TAF12.84078063
5ICK2.77304936
6DDR22.75450184
7MAP3K62.70899100
8BUB12.59810487
9PNCK2.47240142
10TSSK62.17594086
11TNIK2.14713934
12BRD42.02337235
13CDK61.96733685
14CASK1.94669825
15CDK71.93958504
16NEK21.92217799
17PBK1.89915381
18PDGFRA1.87634134
19TTK1.66648979
20PKN21.65109343
21STK31.62749641
22MAP3K101.61379661
23MKNK11.59856133
24LATS21.59278826
25DMPK1.58664097
26ATR1.58074143
27TTN1.54459791
28CHEK21.48404449
29MTOR1.43370713
30RPS6KB21.43321331
31MAPK151.40753602
32VRK21.37014619
33NEK11.34728776
34MKNK21.31015733
35WNK31.26443181
36PLK11.26242466
37ZAK1.25402918
38STK38L1.25328647
39DYRK31.25074780
40ERBB31.24839166
41CAMK1D1.22303115
42BMX1.20930379
43ATM1.17315591
44BRSK21.16324999
45SIK11.14108607
46AURKB1.13474053
47EEF2K1.13312347
48WEE11.11660644
49TYRO31.11348539
50MAP3K91.10188910
51TRPM71.09302787
52LMTK21.09274433
53EIF2AK31.08663066
54CDK41.08662369
55CHEK11.06206440
56PRKD21.05830406
57SRPK11.05340104
58TRIB31.05028580
59BRSK11.04287106
60TGFBR11.03865230
61RPS6KA41.03372094
62YES11.02162099
63DYRK1B1.01776640
64FGFR11.01130333
65ERBB41.01055322
66OBSCN0.98757455
67FGFR20.95710400
68VRK10.93521335
69STK100.92682883
70BMPR1B0.92441481
71EIF2AK10.92171823
72BCR0.90039584
73ACVR1B0.89845155
74CDK20.89032939
75PIM10.88305394
76CDK80.85155538
77AKT30.85127237
78PLK40.85091394
79MET0.82544868
80RIPK10.82269712
81TRIM280.81967671
82PLK30.81603979
83EIF2AK20.81317077
84MAP3K80.79231844
85NLK0.78867501
86PLK20.75954509
87MST40.74735858
88MELK0.74561667
89CDK10.73494765
90NUAK10.73151209
91MAP3K40.72838548
92CDC42BPA0.72766779
93CDK90.71339022
94STK40.70149286
95FLT30.70001752
96SMG10.69934836
97CAMK1G0.64957075
98PHKG10.64575866
99PHKG20.64575866
100PDGFRB0.64365539
101STK390.63946116
102MAP3K110.63329355
103EPHA20.63015090
104RPS6KC10.62943403
105RPS6KL10.62943403
106PAK20.62601903
107MATK0.62559516
108GSK3A0.60824101
109EPHB20.60377212
110PTK60.59539520
111MAPK140.58256888
112CSNK1G10.58086432
113MAPK10.57912190
114HIPK20.57903525
115PRKAA10.57845623
116CDK30.57248632
117CSNK1E0.56700971
118TAOK20.56459231
119PRKDC0.55055819
120PINK10.54964601
121ALK0.54355029
122PAK40.53102713
123PASK0.53021128
124MAPK110.52565139
125AKT20.52504525
126PRKD30.52223728
127WNK10.51802142
128RPS6KA60.51275228
129AKT10.50792432
130FRK0.50355038
131RPS6KB10.50027692
132UHMK10.49420222
133MARK10.48930612
134DYRK20.43629208
135BRAF0.42709132
136SGK20.40778655
137MST1R0.39612628
138IRAK20.39531674
139STK240.35332302
140GSK3B0.35153983
141CSNK1A1L0.35031577
142OXSR10.32506612
143PTK20.32223713
144AURKA0.26895111

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034303.50829393
2DNA replication_Homo sapiens_hsa030303.14953893
3Base excision repair_Homo sapiens_hsa034102.84160994
4Cell cycle_Homo sapiens_hsa041102.83661565
5RNA transport_Homo sapiens_hsa030132.52048936
6Adherens junction_Homo sapiens_hsa045202.40230739
7mRNA surveillance pathway_Homo sapiens_hsa030152.39528308
8Spliceosome_Homo sapiens_hsa030402.21507549
9Basal cell carcinoma_Homo sapiens_hsa052172.20531785
10Homologous recombination_Homo sapiens_hsa034402.10495948
11Hippo signaling pathway_Homo sapiens_hsa043902.08436582
12Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.07224132
13Lysine degradation_Homo sapiens_hsa003102.04710475
14Fanconi anemia pathway_Homo sapiens_hsa034601.99278783
15TGF-beta signaling pathway_Homo sapiens_hsa043501.98459957
16MicroRNAs in cancer_Homo sapiens_hsa052061.91377210
17Fatty acid biosynthesis_Homo sapiens_hsa000611.85945798
18Hedgehog signaling pathway_Homo sapiens_hsa043401.84119695
19p53 signaling pathway_Homo sapiens_hsa041151.82741251
20Nucleotide excision repair_Homo sapiens_hsa034201.80574608
21One carbon pool by folate_Homo sapiens_hsa006701.78207042
22Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.75103688
23RNA degradation_Homo sapiens_hsa030181.71599456
24Notch signaling pathway_Homo sapiens_hsa043301.68641546
25Small cell lung cancer_Homo sapiens_hsa052221.51945814
26Non-homologous end-joining_Homo sapiens_hsa034501.51851428
27Transcriptional misregulation in cancer_Homo sapiens_hsa052021.50726015
28mTOR signaling pathway_Homo sapiens_hsa041501.46645317
29Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.44677456
30Chronic myeloid leukemia_Homo sapiens_hsa052201.37938610
31Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.32653523
32Wnt signaling pathway_Homo sapiens_hsa043101.31652096
33Steroid biosynthesis_Homo sapiens_hsa001001.29967911
34Colorectal cancer_Homo sapiens_hsa052101.28997964
35Viral myocarditis_Homo sapiens_hsa054161.27739421
36Proteoglycans in cancer_Homo sapiens_hsa052051.23799957
37Thyroid cancer_Homo sapiens_hsa052161.11089431
38Prostate cancer_Homo sapiens_hsa052151.07882883
39HTLV-I infection_Homo sapiens_hsa051661.07384376
40Focal adhesion_Homo sapiens_hsa045101.07365748
41Bladder cancer_Homo sapiens_hsa052191.07092651
42Vitamin B6 metabolism_Homo sapiens_hsa007501.05831138
43Basal transcription factors_Homo sapiens_hsa030221.05549314
44Tight junction_Homo sapiens_hsa045301.03848573
45Oocyte meiosis_Homo sapiens_hsa041141.02455653
46Propanoate metabolism_Homo sapiens_hsa006400.99862681
47Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.99638153
48Protein export_Homo sapiens_hsa030600.99107903
49Viral carcinogenesis_Homo sapiens_hsa052030.98407911
50Circadian rhythm_Homo sapiens_hsa047100.98123456
51Endometrial cancer_Homo sapiens_hsa052130.97471540
52Longevity regulating pathway - mammal_Homo sapiens_hsa042110.96943595
53Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.96048516
54Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.96002629
55Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.94470671
56Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.93072509
57Pathways in cancer_Homo sapiens_hsa052000.91695701
58Pyruvate metabolism_Homo sapiens_hsa006200.91503773
59Selenocompound metabolism_Homo sapiens_hsa004500.91376964
60AMPK signaling pathway_Homo sapiens_hsa041520.90751563
61Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.89322483
62ECM-receptor interaction_Homo sapiens_hsa045120.87669245
63Herpes simplex infection_Homo sapiens_hsa051680.84708834
64Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.84104577
65Central carbon metabolism in cancer_Homo sapiens_hsa052300.83116047
66Thyroid hormone signaling pathway_Homo sapiens_hsa049190.83103836
67Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.79994414
68Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.78986602
69Dorso-ventral axis formation_Homo sapiens_hsa043200.77487956
70FoxO signaling pathway_Homo sapiens_hsa040680.77367384
71Melanoma_Homo sapiens_hsa052180.76958377
72Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.76505663
73Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.76212114
74Pancreatic cancer_Homo sapiens_hsa052120.75830421
75Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.74782145
76Axon guidance_Homo sapiens_hsa043600.73357239
77Insulin signaling pathway_Homo sapiens_hsa049100.70370248
78PI3K-Akt signaling pathway_Homo sapiens_hsa041510.69943706
79Regulation of actin cytoskeleton_Homo sapiens_hsa048100.67582115
80Biosynthesis of amino acids_Homo sapiens_hsa012300.65697795
81Glucagon signaling pathway_Homo sapiens_hsa049220.63293222
82Purine metabolism_Homo sapiens_hsa002300.63095917
83Systemic lupus erythematosus_Homo sapiens_hsa053220.62365145
84Insulin resistance_Homo sapiens_hsa049310.60845485
85Acute myeloid leukemia_Homo sapiens_hsa052210.60667615
86Dilated cardiomyopathy_Homo sapiens_hsa054140.59618017
87Hepatitis B_Homo sapiens_hsa051610.59435014
88HIF-1 signaling pathway_Homo sapiens_hsa040660.58772161
89Alcoholism_Homo sapiens_hsa050340.58715811
90Epstein-Barr virus infection_Homo sapiens_hsa051690.57512191
91Proteasome_Homo sapiens_hsa030500.56969457
922-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.56767409
93Non-small cell lung cancer_Homo sapiens_hsa052230.54453657
94AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.52789826
95Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.52229256
96Nicotine addiction_Homo sapiens_hsa050330.49505011
97Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.47175907
98Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.46217892
99Pyrimidine metabolism_Homo sapiens_hsa002400.44479183
100Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.41616420
101Fatty acid metabolism_Homo sapiens_hsa012120.41496006
102Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.40908828
103Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.40569093
104Shigellosis_Homo sapiens_hsa051310.39006321
105Gap junction_Homo sapiens_hsa045400.38363951
106RNA polymerase_Homo sapiens_hsa030200.37835846
107Glioma_Homo sapiens_hsa052140.33305020
108VEGF signaling pathway_Homo sapiens_hsa043700.32876202
109Long-term depression_Homo sapiens_hsa047300.32572790
110Prolactin signaling pathway_Homo sapiens_hsa049170.32174540
111Melanogenesis_Homo sapiens_hsa049160.31996652
112ErbB signaling pathway_Homo sapiens_hsa040120.31349655
113Fatty acid elongation_Homo sapiens_hsa000620.31185933
114Rap1 signaling pathway_Homo sapiens_hsa040150.29267612
115Vitamin digestion and absorption_Homo sapiens_hsa049770.28996406
116Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.27738392
117Arginine and proline metabolism_Homo sapiens_hsa003300.27605140
118Thyroid hormone synthesis_Homo sapiens_hsa049180.27528386
119Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.27467235
120Carbon metabolism_Homo sapiens_hsa012000.27334298
121Starch and sucrose metabolism_Homo sapiens_hsa005000.26804665
122Taste transduction_Homo sapiens_hsa047420.26783697
123Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.26331917
124Cysteine and methionine metabolism_Homo sapiens_hsa002700.25420711
125Leukocyte transendothelial migration_Homo sapiens_hsa046700.24654205
126MAPK signaling pathway_Homo sapiens_hsa040100.24404775
127Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.24075853
128Platelet activation_Homo sapiens_hsa046110.23607977
129Renal cell carcinoma_Homo sapiens_hsa052110.21667016

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