PSMG3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.60561071
2viral transcription (GO:0019083)5.54180464
3ribosomal small subunit biogenesis (GO:0042274)5.53707624
4translational termination (GO:0006415)5.39639769
5maturation of SSU-rRNA (GO:0030490)5.27448992
6mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.07951287
7DNA deamination (GO:0045006)5.00759232
8proteasome assembly (GO:0043248)4.98122145
9SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.96591370
10ribosomal large subunit biogenesis (GO:0042273)4.93362770
11cotranslational protein targeting to membrane (GO:0006613)4.92932727
12protein targeting to ER (GO:0045047)4.87058747
13translational elongation (GO:0006414)4.75289673
14ATP synthesis coupled proton transport (GO:0015986)4.73765977
15energy coupled proton transport, down electrochemical gradient (GO:0015985)4.73765977
16chaperone-mediated protein transport (GO:0072321)4.69481088
17protein localization to endoplasmic reticulum (GO:0070972)4.67259223
18establishment of protein localization to endoplasmic reticulum (GO:0072599)4.60902999
19mitochondrial respiratory chain complex assembly (GO:0033108)4.58887137
20respiratory chain complex IV assembly (GO:0008535)4.48188317
21translational initiation (GO:0006413)4.44415052
22negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.42050432
23cellular protein complex disassembly (GO:0043624)4.28546111
24cytochrome complex assembly (GO:0017004)4.27009655
25viral life cycle (GO:0019058)4.24608656
26formation of translation preinitiation complex (GO:0001731)4.22960673
27DNA strand elongation involved in DNA replication (GO:0006271)4.22205192
28nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.20385940
29translation (GO:0006412)4.20066148
30ribonucleoprotein complex biogenesis (GO:0022613)4.13841553
31termination of RNA polymerase III transcription (GO:0006386)4.13027823
32transcription elongation from RNA polymerase III promoter (GO:0006385)4.13027823
33telomere maintenance via semi-conservative replication (GO:0032201)4.11061836
34regulation of cellular amino acid metabolic process (GO:0006521)4.10083394
35positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.09253592
36negative regulation of ligase activity (GO:0051352)4.08438050
37negative regulation of ubiquitin-protein transferase activity (GO:0051444)4.08438050
38regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.01746413
39establishment of protein localization to mitochondrial membrane (GO:0090151)3.99759359
40establishment of integrated proviral latency (GO:0075713)3.99505874
41DNA strand elongation (GO:0022616)3.99257028
42anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.97493576
43DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.95834855
44rRNA modification (GO:0000154)3.92076017
45deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.90996477
46signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.89133132
47intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.89133132
48nucleobase biosynthetic process (GO:0046112)3.87132320
49rRNA processing (GO:0006364)3.86806590
50signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.85972765
51signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.85972765
52signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.85972765
53purine nucleobase biosynthetic process (GO:0009113)3.85016764
547-methylguanosine mRNA capping (GO:0006370)3.84470467
55spliceosomal snRNP assembly (GO:0000387)3.82226479
56peptidyl-histidine modification (GO:0018202)3.79154280
57signal transduction involved in DNA integrity checkpoint (GO:0072401)3.77886162
58signal transduction involved in DNA damage checkpoint (GO:0072422)3.77886162
597-methylguanosine RNA capping (GO:0009452)3.77574678
60RNA capping (GO:0036260)3.77574678
61pseudouridine synthesis (GO:0001522)3.76991628
62antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.75899084
63protein targeting to mitochondrion (GO:0006626)3.72220466
64signal transduction involved in cell cycle checkpoint (GO:0072395)3.71949040
65cellular component biogenesis (GO:0044085)3.71666053
66protein complex disassembly (GO:0043241)3.70339692
67L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.70172706
68rRNA metabolic process (GO:0016072)3.69266784
69protein deneddylation (GO:0000338)3.64741439
70mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.64722565
71telomere maintenance via recombination (GO:0000722)3.64319530
72GTP biosynthetic process (GO:0006183)3.63092647
73DNA replication initiation (GO:0006270)3.62160908
74establishment of protein localization to mitochondrion (GO:0072655)3.61981612
75macromolecular complex disassembly (GO:0032984)3.55983866
76maturation of 5.8S rRNA (GO:0000460)3.53737292
77regulation of mitochondrial translation (GO:0070129)3.53072613
78mannosylation (GO:0097502)3.50566543
79positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.49010274
80guanosine-containing compound biosynthetic process (GO:1901070)3.48963517
81mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.47305067
82mitochondrial respiratory chain complex I assembly (GO:0032981)3.47305067
83NADH dehydrogenase complex assembly (GO:0010257)3.47305067
84antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.46974268
85respiratory electron transport chain (GO:0022904)3.45161028
86DNA replication checkpoint (GO:0000076)3.42684258
87protein neddylation (GO:0045116)3.41797806
88UTP biosynthetic process (GO:0006228)3.41515490
89positive regulation of ligase activity (GO:0051351)3.39368449
90establishment of viral latency (GO:0019043)3.38658534
91electron transport chain (GO:0022900)3.37743679
92replication fork processing (GO:0031297)3.36821693
93CENP-A containing nucleosome assembly (GO:0034080)3.36010494
94transcription-coupled nucleotide-excision repair (GO:0006283)3.34865107
95ribosome biogenesis (GO:0042254)3.34784154
96protein localization to mitochondrion (GO:0070585)3.34009113
97transcription from mitochondrial promoter (GO:0006390)3.33459961
98exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.33134345
99RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.32514936
100tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.32514936
101nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.30042510
102protein K6-linked ubiquitination (GO:0085020)3.28019735
103mitotic recombination (GO:0006312)3.25936554
104deoxyribose phosphate biosynthetic process (GO:0046385)3.25413647
1052-deoxyribonucleotide biosynthetic process (GO:0009265)3.25413647
106protein complex biogenesis (GO:0070271)3.24450032
107pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.23913841
108mitochondrial RNA metabolic process (GO:0000959)3.23347523
109chromatin remodeling at centromere (GO:0031055)3.22698890
110nuclear-transcribed mRNA catabolic process (GO:0000956)3.22077900
111cullin deneddylation (GO:0010388)3.21090248
112deoxyribonucleotide biosynthetic process (GO:0009263)3.20259218
113platelet dense granule organization (GO:0060155)3.07577223
114metallo-sulfur cluster assembly (GO:0031163)3.05072768
115iron-sulfur cluster assembly (GO:0016226)3.05072768
116pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.04929058
117tRNA processing (GO:0008033)3.03474705
118pteridine-containing compound biosynthetic process (GO:0042559)3.00159747
119pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.00029493
120water-soluble vitamin biosynthetic process (GO:0042364)2.97213156
121inner mitochondrial membrane organization (GO:0007007)2.97038500
122oxidative phosphorylation (GO:0006119)2.96531989
123rRNA methylation (GO:0031167)2.96202356
124DNA damage response, detection of DNA damage (GO:0042769)2.93182165
125CTP metabolic process (GO:0046036)2.92238825
126CTP biosynthetic process (GO:0006241)2.92238825
127intracellular protein transmembrane import (GO:0044743)2.91807250
128purine nucleoside triphosphate biosynthetic process (GO:0009145)2.89000747
129UTP metabolic process (GO:0046051)2.88184084
130mitochondrial transport (GO:0006839)2.87105414
131purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.84878203
132base-excision repair, AP site formation (GO:0006285)2.81215483
133protein-cofactor linkage (GO:0018065)2.79882913
134tRNA metabolic process (GO:0006399)2.79520324
135regulation of ubiquitin-protein transferase activity (GO:0051438)2.78142622
136dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.77461590
137maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.75700039
138pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.71646649
139regulation of ligase activity (GO:0051340)2.68958165

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.27582882
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.67280051
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.45077765
4GABP_17652178_ChIP-ChIP_JURKAT_Human4.28390310
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.20349368
6EST1_17652178_ChIP-ChIP_JURKAT_Human4.12842568
7* JARID1A_20064375_ChIP-Seq_MESCs_Mouse4.06199078
8SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.99533606
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.74384497
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.62719460
11CREB1_15753290_ChIP-ChIP_HEK293T_Human3.46145385
12MYC_18358816_ChIP-ChIP_MESCs_Mouse3.29758587
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.22587893
14ELF1_17652178_ChIP-ChIP_JURKAT_Human3.14003040
15MYC_19030024_ChIP-ChIP_MESCs_Mouse2.93386036
16MYC_19079543_ChIP-ChIP_MESCs_Mouse2.89734854
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.87508624
18HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.85979361
19E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.84553124
20FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.81437674
21CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.76694644
22E2F4_17652178_ChIP-ChIP_JURKAT_Human2.70149044
23VDR_23849224_ChIP-Seq_CD4+_Human2.64136528
24XRN2_22483619_ChIP-Seq_HELA_Human2.54482583
25THAP11_20581084_ChIP-Seq_MESCs_Mouse2.46997397
26DCP1A_22483619_ChIP-Seq_HELA_Human2.44545303
27E2F1_18555785_ChIP-Seq_MESCs_Mouse2.33966645
28FOXP3_21729870_ChIP-Seq_TREG_Human2.27724175
29YY1_21170310_ChIP-Seq_MESCs_Mouse2.26004179
30* SRF_21415370_ChIP-Seq_HL-1_Mouse2.23612397
31NELFA_20434984_ChIP-Seq_ESCs_Mouse2.21451112
32* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.21226243
33* GABP_19822575_ChIP-Seq_HepG2_Human2.14026254
34PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.07103792
35TTF2_22483619_ChIP-Seq_HELA_Human2.04326368
36ELK1_19687146_ChIP-ChIP_HELA_Human2.00491774
37SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.93353886
38* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.88389529
39ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.81774671
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.73316604
41ZNF274_21170338_ChIP-Seq_K562_Hela1.72748985
42MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.68194483
43TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.67772545
44HOXB4_20404135_ChIP-ChIP_EML_Mouse1.65532377
45FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.64954476
46MYCN_18555785_ChIP-Seq_MESCs_Mouse1.63341820
47PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.61454364
48MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.56091924
49YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.54747298
50* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.51024277
51MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.47825759
52ELK1_22589737_ChIP-Seq_MCF10A_Human1.45375799
53ERG_20887958_ChIP-Seq_HPC-7_Mouse1.45336480
54NANOG_18555785_ChIP-Seq_MESCs_Mouse1.43549413
55FOXM1_23109430_ChIP-Seq_U2OS_Human1.43194851
56ZFX_18555785_ChIP-Seq_MESCs_Mouse1.41410473
57AR_21909140_ChIP-Seq_LNCAP_Human1.31909997
58MYC_18940864_ChIP-ChIP_HL60_Human1.29280761
59SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.25809395
60CIITA_25753668_ChIP-Seq_RAJI_Human1.25671776
61CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.24208410
62KDM5A_27292631_Chip-Seq_BREAST_Human1.22390850
63HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.21108467
64E2F1_21310950_ChIP-Seq_MCF-7_Human1.20366165
65BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.14924914
66POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.14910485
67VDR_22108803_ChIP-Seq_LS180_Human1.14478455
68PADI4_21655091_ChIP-ChIP_MCF-7_Human1.13738335
69TP53_22573176_ChIP-Seq_HFKS_Human1.13652503
70KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.11129015
71CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.09077659
72SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.08835123
73CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.08831723
74* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.07404131
75CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.05944414
76TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.04398243
77IRF1_19129219_ChIP-ChIP_H3396_Human1.02405167
78E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.99495824
79ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.98725960
80CTCF_18555785_ChIP-Seq_MESCs_Mouse0.97150353
81CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.96971672
82EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.96645141
83GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.92577495
84NOTCH1_21737748_ChIP-Seq_TLL_Human0.90927119
85HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.89655179
86SPI1_23547873_ChIP-Seq_NB4_Human0.89541670
87PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.89400409
88EWS_26573619_Chip-Seq_HEK293_Human0.89195847
89SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.88451444
90HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.87834359
91TFEB_21752829_ChIP-Seq_HELA_Human0.87828455
92IGF1R_20145208_ChIP-Seq_DFB_Human0.84578495
93SRY_22984422_ChIP-ChIP_TESTIS_Rat0.84552279
94* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84406253
95* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.84151428
96SOX17_20123909_ChIP-Seq_XEN_Mouse0.80203798
97YY1_22570637_ChIP-Seq_MALME-3M_Human0.78932184
98KLF4_18555785_ChIP-Seq_MESCs_Mouse0.77842320
99SOX2_18555785_ChIP-Seq_MESCs_Mouse0.77264672
100FOXA1_25329375_ChIP-Seq_VCAP_Human0.76338292
101FOXA1_27270436_Chip-Seq_PROSTATE_Human0.76338292
102STAT3_1855785_ChIP-Seq_MESCs_Mouse0.74362883
103EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.74061594
104CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.74049677
105OCT4_18692474_ChIP-Seq_MEFs_Mouse0.72757723
106DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.72408388
107EGR1_23403033_ChIP-Seq_LIVER_Mouse0.71788306
108DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.71228216
109TBX5_21415370_ChIP-Seq_HL-1_Mouse0.70987320
110AR_20517297_ChIP-Seq_VCAP_Human0.70799576
111CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.69783768
112CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.68792927
113RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.68673754
114* FOXP1_21924763_ChIP-Seq_HESCs_Human0.66902016
115RBPJ_22232070_ChIP-Seq_NCS_Mouse0.66808335
116POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.66765306
117NCOR_22424771_ChIP-Seq_293T_Human0.66742220
118ELF5_23300383_ChIP-Seq_T47D_Human0.66311826
119ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.66037612
120SOX2_18692474_ChIP-Seq_MEFs_Mouse0.64630499

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.12301815
2MP0004957_abnormal_blastocyst_morpholog4.29032166
3MP0010094_abnormal_chromosome_stability3.81049164
4MP0003806_abnormal_nucleotide_metabolis3.80371927
5MP0003111_abnormal_nucleus_morphology3.54620810
6MP0008058_abnormal_DNA_repair3.36376084
7MP0009379_abnormal_foot_pigmentation3.35414324
8MP0003077_abnormal_cell_cycle3.24280681
9MP0008057_abnormal_DNA_replication2.95166861
10MP0008932_abnormal_embryonic_tissue2.78468207
11MP0001529_abnormal_vocalization2.68936638
12MP0003718_maternal_effect2.66771999
13MP0002837_dystrophic_cardiac_calcinosis2.39636984
14MP0006036_abnormal_mitochondrial_physio2.30917614
15MP0002396_abnormal_hematopoietic_system2.26241218
16MP0003186_abnormal_redox_activity2.22590508
17MP0008007_abnormal_cellular_replicative2.13785363
18MP0004147_increased_porphyrin_level2.11948135
19MP0001905_abnormal_dopamine_level2.07134305
20MP0009333_abnormal_splenocyte_physiolog2.06908190
21MP0006035_abnormal_mitochondrial_morpho2.06520506
22MP0006292_abnormal_olfactory_placode2.04960749
23MP0003786_premature_aging2.04613483
24MP0006072_abnormal_retinal_apoptosis2.02983666
25MP0003195_calcinosis2.02143211
26MP0008995_early_reproductive_senescence1.95289099
27MP0002876_abnormal_thyroid_physiology1.89882809
28MP0008875_abnormal_xenobiotic_pharmacok1.83709209
29MP0003656_abnormal_erythrocyte_physiolo1.79699283
30MP0005551_abnormal_eye_electrophysiolog1.69718219
31MP0001764_abnormal_homeostasis1.62542895
32MP0005646_abnormal_pituitary_gland1.59278449
33MP0001730_embryonic_growth_arrest1.57560299
34MP0005408_hypopigmentation1.57050710
35MP0005084_abnormal_gallbladder_morpholo1.56977277
36MP0001968_abnormal_touch/_nociception1.54917093
37MP0002132_abnormal_respiratory_system1.52068397
38MP0008260_abnormal_autophagy1.51590789
39MP0000490_abnormal_crypts_of1.51418871
40MP0005075_abnormal_melanosome_morpholog1.48690583
41MP0003123_paternal_imprinting1.46277751
42MP0002638_abnormal_pupillary_reflex1.44173419
43MP0009046_muscle_twitch1.41688581
44MP0005645_abnormal_hypothalamus_physiol1.39085105
45MP0009697_abnormal_copulation1.36992712
46MP0005332_abnormal_amino_acid1.35484408
47MP0003315_abnormal_perineum_morphology1.31903841
48MP0000350_abnormal_cell_proliferation1.30560259
49MP0002938_white_spotting1.26653427
50MP0000358_abnormal_cell_content/1.26474916
51MP0003136_yellow_coat_color1.21948630
52MP0001853_heart_inflammation1.20579418
53MP0001929_abnormal_gametogenesis1.19606512
54MP0000313_abnormal_cell_death1.17961629
55MP0005253_abnormal_eye_physiology1.17960833
56MP0004142_abnormal_muscle_tone1.16972242
57MP0002254_reproductive_system_inflammat1.16618708
58MP0001727_abnormal_embryo_implantation1.16335708
59MP0003763_abnormal_thymus_physiology1.15956151
60MP0002019_abnormal_tumor_incidence1.13946061
61MP0005451_abnormal_body_composition1.13940529
62MP0002163_abnormal_gland_morphology1.12874173
63MP0001919_abnormal_reproductive_system1.11228230
64MP0005671_abnormal_response_to1.10818046
65MP0002102_abnormal_ear_morphology1.10004211
66MP0005367_renal/urinary_system_phenotyp1.09769012
67MP0000516_abnormal_urinary_system1.09769012
68MP0006276_abnormal_autonomic_nervous1.07970712
69MP0002160_abnormal_reproductive_system1.05090612
70MP0000372_irregular_coat_pigmentation1.03804904
71MP0001545_abnormal_hematopoietic_system1.03048777
72MP0005397_hematopoietic_system_phenotyp1.03048777
73MP0001661_extended_life_span1.02301206
74MP0002398_abnormal_bone_marrow1.01627321
75MP0000689_abnormal_spleen_morphology1.01232047
76MP0005410_abnormal_fertilization1.01121714
77MP0008877_abnormal_DNA_methylation1.01114099
78MP0002722_abnormal_immune_system1.00773848
79MP0000653_abnormal_sex_gland1.00615613
80MP0002080_prenatal_lethality1.00214653
81MP0003880_abnormal_central_pattern0.98470291
82MP0001986_abnormal_taste_sensitivity0.95357338
83MP0001944_abnormal_pancreas_morphology0.95168244
84MP0005083_abnormal_biliary_tract0.93602302
85MP0009785_altered_susceptibility_to0.92890947
86MP0005636_abnormal_mineral_homeostasis0.92550697
87MP0002234_abnormal_pharynx_morphology0.91788937
88MP0002429_abnormal_blood_cell0.91537970
89MP0000647_abnormal_sebaceous_gland0.91090337
90MP0005220_abnormal_exocrine_pancreas0.89891522
91MP0000427_abnormal_hair_cycle0.89413786
92MP0005409_darkened_coat_color0.88386341
93MP0000631_abnormal_neuroendocrine_gland0.88323687
94MP0000703_abnormal_thymus_morphology0.87103394
95MP0001542_abnormal_bone_strength0.87064483
96MP0003698_abnormal_male_reproductive0.87034502
97MP0001697_abnormal_embryo_size0.85983185
98MP0002090_abnormal_vision0.85778913
99MP0002095_abnormal_skin_pigmentation0.84801763
100MP0009745_abnormal_behavioral_response0.83482147
101MP0003011_delayed_dark_adaptation0.82791272
102MP0005174_abnormal_tail_pigmentation0.81660519
103MP0002693_abnormal_pancreas_physiology0.81054221
104MP0001188_hyperpigmentation0.80959314
105MP0004133_heterotaxia0.80635783
106MP0000465_gastrointestinal_hemorrhage0.79725875
107MP0006054_spinal_hemorrhage0.78167796
108MP0000015_abnormal_ear_pigmentation0.77829659
109MP0001756_abnormal_urination0.77435592
110MP0002277_abnormal_respiratory_mucosa0.77215448
111MP0005266_abnormal_metabolism0.75621787
112MP0005379_endocrine/exocrine_gland_phen0.75072344
113MP0005376_homeostasis/metabolism_phenot0.74919773
114MP0000716_abnormal_immune_system0.74809164
115MP0005670_abnormal_white_adipose0.74186310
116MP0004381_abnormal_hair_follicle0.73707645
117MP0003567_abnormal_fetal_cardiomyocyte0.73331975
118MP0005395_other_phenotype0.73157463
119MP0002751_abnormal_autonomic_nervous0.72901796
120MP0001984_abnormal_olfaction0.72674977
121MP0001324_abnormal_eye_pigmentation0.72600699
122MP0001835_abnormal_antigen_presentation0.72533769
123MP0001119_abnormal_female_reproductive0.72181518
124MP0003221_abnormal_cardiomyocyte_apopto0.71583376
125MP0003137_abnormal_impulse_conducting0.70426960
126MP0005389_reproductive_system_phenotype0.70161004
127MP0002148_abnormal_hypersensitivity_rea0.69286916
128MP0002210_abnormal_sex_determination0.68256751
129MP0004019_abnormal_vitamin_homeostasis0.67936478
130MP0004043_abnormal_pH_regulation0.67053781
131MP0001145_abnormal_male_reproductive0.66713705
132MP0000858_altered_metastatic_potential0.65879078
133MP0005171_absent_coat_pigmentation0.65592047
134MP0005380_embryogenesis_phenotype0.65579204
135MP0001672_abnormal_embryogenesis/_devel0.65579204
136MP0002909_abnormal_adrenal_gland0.65320271
137MP0005025_abnormal_response_to0.63460694
138MP0008872_abnormal_physiological_respon0.63225189
139MP0002420_abnormal_adaptive_immunity0.62870295
140MP0003787_abnormal_imprinting0.62770346
141MP0000371_diluted_coat_color0.62742187
142MP0008873_increased_physiological_sensi0.61964575
143MP0001346_abnormal_lacrimal_gland0.61578862
144MP0002723_abnormal_immune_serum0.60479252
145MP0001819_abnormal_immune_cell0.59971822
146MP0001485_abnormal_pinna_reflex0.59633370
147MP0001800_abnormal_humoral_immune0.58795664
148MP0008789_abnormal_olfactory_epithelium0.58240672
149MP0002736_abnormal_nociception_after0.57363924
150MP0008469_abnormal_protein_level0.55847518

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.81418094
2Abnormal number of erythroid precursors (HP:0012131)5.57284711
3Acute necrotizing encephalopathy (HP:0006965)5.18625129
4Mitochondrial inheritance (HP:0001427)4.83874303
5Abnormal mitochondria in muscle tissue (HP:0008316)4.73960866
6Reticulocytopenia (HP:0001896)4.54251142
7Hepatocellular necrosis (HP:0001404)4.53942210
8Increased CSF lactate (HP:0002490)4.39341421
9Acute encephalopathy (HP:0006846)4.36923171
10Decreased activity of mitochondrial respiratory chain (HP:0008972)4.27302801
11Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.27302801
12Increased hepatocellular lipid droplets (HP:0006565)4.22489610
133-Methylglutaconic aciduria (HP:0003535)4.13936539
14Progressive macrocephaly (HP:0004481)4.12898490
15Hepatic necrosis (HP:0002605)4.08500136
16Macrocytic anemia (HP:0001972)4.05642761
17Birth length less than 3rd percentile (HP:0003561)4.05569365
18Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)4.04988990
19Abnormality of glycolysis (HP:0004366)3.98725924
20Increased serum pyruvate (HP:0003542)3.98725924
21Cerebral hypomyelination (HP:0006808)3.85643029
22Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.77544600
23Lipid accumulation in hepatocytes (HP:0006561)3.76736771
24Increased serum lactate (HP:0002151)3.73521319
25Pallor (HP:0000980)3.52141309
26Aplastic anemia (HP:0001915)3.40252758
27Renal Fanconi syndrome (HP:0001994)3.37677389
28Abnormality of the heme biosynthetic pathway (HP:0010472)3.24009472
29Oral leukoplakia (HP:0002745)3.19781282
30Lactic acidosis (HP:0003128)3.17181754
31Increased intramyocellular lipid droplets (HP:0012240)3.16855351
32Breast hypoplasia (HP:0003187)3.15609733
33Exertional dyspnea (HP:0002875)3.14253686
34Cerebral edema (HP:0002181)3.02936179
35Respiratory failure (HP:0002878)3.01859083
36Microvesicular hepatic steatosis (HP:0001414)2.99964030
37Exercise intolerance (HP:0003546)2.99354979
38Type I transferrin isoform profile (HP:0003642)2.69222787
39Leukodystrophy (HP:0002415)2.66145144
40Increased muscle lipid content (HP:0009058)2.61541432
41Pancreatic cysts (HP:0001737)2.59187910
42Rough bone trabeculation (HP:0100670)2.57938959
43Optic disc pallor (HP:0000543)2.53431161
44CNS demyelination (HP:0007305)2.53306654
45Abnormality of midbrain morphology (HP:0002418)2.52893747
46Molar tooth sign on MRI (HP:0002419)2.52893747
47Respiratory difficulties (HP:0002880)2.51283152
48Pancreatic fibrosis (HP:0100732)2.47216435
49Aplasia/Hypoplasia of the sacrum (HP:0008517)2.42891279
50Pancytopenia (HP:0001876)2.39610968
51True hermaphroditism (HP:0010459)2.36784908
52Carpal bone hypoplasia (HP:0001498)2.35702790
53Progressive microcephaly (HP:0000253)2.35587764
54Emotional lability (HP:0000712)2.35389294
55CNS hypomyelination (HP:0003429)2.34871777
56Methylmalonic aciduria (HP:0012120)2.29848948
57Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.23851126
58Secondary amenorrhea (HP:0000869)2.23627161
59Methylmalonic acidemia (HP:0002912)2.18469331
60Abnormal rod and cone electroretinograms (HP:0008323)2.17237689
61Hyperglycinemia (HP:0002154)2.12330582
62Microretrognathia (HP:0000308)2.10352668
63Reduced antithrombin III activity (HP:0001976)2.10104600
64Generalized aminoaciduria (HP:0002909)2.08771310
65Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.05581187
66Abnormal protein N-linked glycosylation (HP:0012347)2.05581187
67Abnormal protein glycosylation (HP:0012346)2.05581187
68Abnormal glycosylation (HP:0012345)2.05581187
69Premature ovarian failure (HP:0008209)2.04434057
70Testicular atrophy (HP:0000029)2.03940784
71Abnormality of alanine metabolism (HP:0010916)2.03747383
72Hyperalaninemia (HP:0003348)2.03747383
73Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.03747383
74Medial flaring of the eyebrow (HP:0010747)2.03421919
75Aplasia/Hypoplasia of the uvula (HP:0010293)2.01084941
76Delusions (HP:0000746)1.98167715
77Ketoacidosis (HP:0001993)1.97991253
78Abnormality of aromatic amino acid family metabolism (HP:0004338)1.97921730
79Abnormality of methionine metabolism (HP:0010901)1.96562052
80Lethargy (HP:0001254)1.96318285
81Patellar aplasia (HP:0006443)1.96171002
82Abnormality of the anterior horn cell (HP:0006802)1.94872469
83Degeneration of anterior horn cells (HP:0002398)1.94872469
84Megaloblastic anemia (HP:0001889)1.94605073
85Severe visual impairment (HP:0001141)1.94429794
86Abnormality of renal resorption (HP:0011038)1.94031333
87Type II lissencephaly (HP:0007260)1.93851517
88Progressive muscle weakness (HP:0003323)1.93771142
89Abnormality of the ileum (HP:0001549)1.93687145
90Opisthotonus (HP:0002179)1.93469261
91Premature graying of hair (HP:0002216)1.92749492
92Irregular epiphyses (HP:0010582)1.92411077
93Poor head control (HP:0002421)1.91638799
94Nephronophthisis (HP:0000090)1.91485334
95Hypokinesia (HP:0002375)1.91104105
96Abnormality of reticulocytes (HP:0004312)1.90756720
97Unsteady gait (HP:0002317)1.89611430
98Sclerocornea (HP:0000647)1.88902304
99Multiple enchondromatosis (HP:0005701)1.88117622
100Postnatal microcephaly (HP:0005484)1.87203094
101Horseshoe kidney (HP:0000085)1.85973458
102Aplasia/Hypoplasia of the patella (HP:0006498)1.84983719
103Attenuation of retinal blood vessels (HP:0007843)1.84257498
104Abnormality of urine glucose concentration (HP:0011016)1.84154642
105Glycosuria (HP:0003076)1.84154642
106Abnormal trabecular bone morphology (HP:0100671)1.83784864
107Hyperphosphaturia (HP:0003109)1.79706188
108Congenital stationary night blindness (HP:0007642)1.79545398
109Hypoplasia of the pons (HP:0012110)1.79513656
110Abnormality of the preputium (HP:0100587)1.78062385
111Renal cortical cysts (HP:0000803)1.77691891
112Bone marrow hypocellularity (HP:0005528)1.77272102
113Dicarboxylic aciduria (HP:0003215)1.77117263
114Abnormality of dicarboxylic acid metabolism (HP:0010995)1.77117263
115Cellular immunodeficiency (HP:0005374)1.76899700
116Aplasia/hypoplasia of the uterus (HP:0008684)1.76542159
117Pendular nystagmus (HP:0012043)1.74876175
118Abnormality of serum amino acid levels (HP:0003112)1.74256228
119Abnormality of aspartate family amino acid metabolism (HP:0010899)1.74245716
120Poor suck (HP:0002033)1.74124930
121Chromsome breakage (HP:0040012)1.72301572
12211 pairs of ribs (HP:0000878)1.71777009
123Hyperglycinuria (HP:0003108)1.70819869
124Meckel diverticulum (HP:0002245)1.70344836
125Trismus (HP:0000211)1.70176229
126Hypoplasia of the capital femoral epiphysis (HP:0003090)1.69625917
127Occipital encephalocele (HP:0002085)1.69368750
128Hypothermia (HP:0002045)1.69037091
129Decreased electroretinogram (ERG) amplitude (HP:0000654)1.68778189
130Absent thumb (HP:0009777)1.68470335
131IgM deficiency (HP:0002850)1.67708414
132Abnormality of the pons (HP:0007361)1.67584500
133Sensory axonal neuropathy (HP:0003390)1.67474144
134Gliosis (HP:0002171)1.67238606
135Ketosis (HP:0001946)1.66031832
136Furrowed tongue (HP:0000221)1.65651989
137Chromosomal breakage induced by crosslinking agents (HP:0003221)1.64893786
138Thrombocytosis (HP:0001894)1.63677943
139Abnormal lung lobation (HP:0002101)1.63571500
140Cleft eyelid (HP:0000625)1.63076557

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.78218499
2STK164.26049203
3NME24.12213759
4VRK23.83088599
5WEE13.81402246
6EIF2AK13.69255344
7MAP4K22.99861305
8SRPK12.81165160
9FRK2.78751604
10TRIM282.74762307
11EIF2AK32.63125310
12TLK12.56013909
13PIM22.36643205
14VRK12.31449153
15PDK22.10094099
16TSSK62.07202147
17NUAK12.06087107
18ACVR1B2.05959259
19NME12.04414233
20WNK31.95873646
21CDC71.91408084
22NEK11.78290179
23PLK41.74654848
24TESK21.69542209
25PBK1.63042197
26BRSK21.62621902
27CDK191.57454035
28MKNK11.56404307
29MST41.55262349
30ARAF1.53073629
31BMPR1B1.48718067
32WNK41.38841724
33MAP3K121.31410178
34PINK11.28856824
35CCNB11.28115788
36DYRK31.23529015
37BRSK11.22209914
38MAPKAPK31.18667416
39NEK21.15471915
40TNIK1.14837991
41BRAF1.14259005
42BCKDK1.14035922
43PLK11.13576090
44AURKA1.10628173
45KDR1.07507165
46DYRK21.04059241
47TTK1.02355756
48PNCK1.01818280
49MKNK21.00671083
50AURKB1.00448601
51INSRR0.99943351
52PHKG10.94485970
53PHKG20.94485970
54LIMK10.91156989
55MAP3K110.90396242
56CDK70.88766317
57CASK0.85026308
58PLK30.84349586
59PLK20.84064048
60EIF2AK20.83831468
61ABL20.82011195
62CSNK1G20.81904959
63ATR0.81803336
64CSNK1A1L0.81780557
65IRAK40.81208230
66ERBB30.79887353
67RPS6KA40.79746197
68CSNK1G30.79572204
69MYLK0.79207786
70PASK0.78715909
71CSNK2A10.77283655
72CSNK2A20.76622816
73SCYL20.74253010
74PAK10.73528516
75PRKCI0.68988084
76TAF10.67823150
77ILK0.67109785
78CDK80.66495729
79RPS6KB20.62612146
80RPS6KA50.59872773
81MAP2K60.56576918
82CHEK20.54834092
83SIK30.54808741
84CLK10.54746070
85MAP3K80.54057193
86DAPK10.53466306
87MAPKAPK50.53124718
88MUSK0.53085212
89MAP4K10.50737000
90PAK30.50490284
91BLK0.49702527
92LMTK20.48903063
93ATM0.48344178
94PRKCE0.48167727
95ZAK0.47106854
96IKBKB0.46917810
97MAPK130.45825292
98DAPK30.45093746
99BCR0.44841916
100MAP3K30.44312846
101PAK40.44089163
102CHEK10.43808244
103BTK0.42944623
104TESK10.42939325
105PRKCG0.42226513
106TEC0.41567749
107IRAK30.40734820
108PIM10.40153275
109FER0.39900047
110MAP2K70.39444438
111CAMK2D0.39005037
112MST1R0.38877598
113ADRBK20.38598371
114SYK0.38487392
115GRK50.37723649
116GRK70.37417688
117MAP2K30.37067349
118ADRBK10.36948464
119CDK11A0.36842067
120GRK60.35790533
121TXK0.35664649
122MAPK40.35184406
123LYN0.34840527
124CDK40.33886869
125STK40.33604819
126CSNK1G10.33497535
127CDK180.33062474
128CDK140.32462550
129LRRK20.31865606
130RAF10.31284796
131CSNK1A10.31073899
132CDK150.31032657
133STK390.29380281
134OXSR10.28824070
135ZAP700.28362748
136GRK10.27686479
137YES10.27041190

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.11248482
2Proteasome_Homo sapiens_hsa030504.92139689
3DNA replication_Homo sapiens_hsa030303.87326426
4RNA polymerase_Homo sapiens_hsa030203.82209513
5Oxidative phosphorylation_Homo sapiens_hsa001903.21878602
6Mismatch repair_Homo sapiens_hsa034303.05040313
7Parkinsons disease_Homo sapiens_hsa050122.94110400
8Spliceosome_Homo sapiens_hsa030402.79962560
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.77676215
10Pyrimidine metabolism_Homo sapiens_hsa002402.76872024
11Protein export_Homo sapiens_hsa030602.50327091
12Homologous recombination_Homo sapiens_hsa034402.42013129
13Nucleotide excision repair_Homo sapiens_hsa034202.21319955
14Base excision repair_Homo sapiens_hsa034102.19134711
15Huntingtons disease_Homo sapiens_hsa050162.16305317
16RNA transport_Homo sapiens_hsa030132.05284627
17Alzheimers disease_Homo sapiens_hsa050101.85615791
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.70536918
19Non-homologous end-joining_Homo sapiens_hsa034501.68983267
20Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.65058625
21Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.63565829
22One carbon pool by folate_Homo sapiens_hsa006701.57171164
23Purine metabolism_Homo sapiens_hsa002301.52730423
24Basal transcription factors_Homo sapiens_hsa030221.51897814
25Folate biosynthesis_Homo sapiens_hsa007901.44159632
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.40790056
27Butanoate metabolism_Homo sapiens_hsa006501.39831250
28Fanconi anemia pathway_Homo sapiens_hsa034601.37286387
29Cell cycle_Homo sapiens_hsa041101.35456487
30RNA degradation_Homo sapiens_hsa030181.31724486
31Sulfur relay system_Homo sapiens_hsa041221.31169933
32Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.30691944
33Maturity onset diabetes of the young_Homo sapiens_hsa049501.23503051
34Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.18933990
35Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.11980110
36Phototransduction_Homo sapiens_hsa047441.03257184
37Pentose phosphate pathway_Homo sapiens_hsa000301.02344979
38Cysteine and methionine metabolism_Homo sapiens_hsa002701.00207096
39Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.00093235
40Fatty acid elongation_Homo sapiens_hsa000620.97769219
41Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.97593325
42Glutathione metabolism_Homo sapiens_hsa004800.92706869
43Drug metabolism - other enzymes_Homo sapiens_hsa009830.88201910
44Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.87634032
45Vitamin B6 metabolism_Homo sapiens_hsa007500.84587920
46Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.83574246
47Epstein-Barr virus infection_Homo sapiens_hsa051690.82456641
48Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.76493141
49Metabolic pathways_Homo sapiens_hsa011000.76393886
50Nitrogen metabolism_Homo sapiens_hsa009100.74578776
51Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.72269301
52p53 signaling pathway_Homo sapiens_hsa041150.72050321
53Biosynthesis of amino acids_Homo sapiens_hsa012300.71455953
54Cardiac muscle contraction_Homo sapiens_hsa042600.69190318
55Tryptophan metabolism_Homo sapiens_hsa003800.67962387
56Primary bile acid biosynthesis_Homo sapiens_hsa001200.65822429
57Systemic lupus erythematosus_Homo sapiens_hsa053220.64639395
58Carbon metabolism_Homo sapiens_hsa012000.63732249
59Regulation of autophagy_Homo sapiens_hsa041400.63342775
60Cyanoamino acid metabolism_Homo sapiens_hsa004600.62047097
61mRNA surveillance pathway_Homo sapiens_hsa030150.61138763
62Arginine and proline metabolism_Homo sapiens_hsa003300.58199859
63Fatty acid metabolism_Homo sapiens_hsa012120.57304801
64Pentose and glucuronate interconversions_Homo sapiens_hsa000400.57289282
65SNARE interactions in vesicular transport_Homo sapiens_hsa041300.56544591
66Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.53427678
67beta-Alanine metabolism_Homo sapiens_hsa004100.52307785
68Pyruvate metabolism_Homo sapiens_hsa006200.52139398
69Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.50659834
70Primary immunodeficiency_Homo sapiens_hsa053400.48108665
712-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.46155900
72Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.44429900
73Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.43507856
74Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.43432648
75Arachidonic acid metabolism_Homo sapiens_hsa005900.42935475
76Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.42676981
77Allograft rejection_Homo sapiens_hsa053300.41295932
78N-Glycan biosynthesis_Homo sapiens_hsa005100.40780011
79Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.39808600
80Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.39734086
81Selenocompound metabolism_Homo sapiens_hsa004500.39028884
82Antigen processing and presentation_Homo sapiens_hsa046120.38465253
83Fructose and mannose metabolism_Homo sapiens_hsa000510.37268300
84Steroid biosynthesis_Homo sapiens_hsa001000.36761203
85Tyrosine metabolism_Homo sapiens_hsa003500.34911251
86Steroid hormone biosynthesis_Homo sapiens_hsa001400.34901138
87Phenylalanine metabolism_Homo sapiens_hsa003600.34777991
88alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.34248692
89Caffeine metabolism_Homo sapiens_hsa002320.33290092
90Peroxisome_Homo sapiens_hsa041460.30746400
91Linoleic acid metabolism_Homo sapiens_hsa005910.27835499
92Olfactory transduction_Homo sapiens_hsa047400.27361398
93Retinol metabolism_Homo sapiens_hsa008300.27188266
94Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.26520358
95Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.26268506
96Fatty acid degradation_Homo sapiens_hsa000710.26258785
97Histidine metabolism_Homo sapiens_hsa003400.24015940
98Sphingolipid metabolism_Homo sapiens_hsa006000.22648585
99Ether lipid metabolism_Homo sapiens_hsa005650.22565155
100Oocyte meiosis_Homo sapiens_hsa041140.21259898
101Collecting duct acid secretion_Homo sapiens_hsa049660.20280269
102Herpes simplex infection_Homo sapiens_hsa051680.19973966
103Vibrio cholerae infection_Homo sapiens_hsa051100.19348243
104Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.19207774
105Galactose metabolism_Homo sapiens_hsa000520.19111929
106Legionellosis_Homo sapiens_hsa051340.18940373
107Graft-versus-host disease_Homo sapiens_hsa053320.17576082
108Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.17484013
109Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.16869661
110Renin-angiotensin system_Homo sapiens_hsa046140.15542096
111Alcoholism_Homo sapiens_hsa050340.15300986
112Propanoate metabolism_Homo sapiens_hsa006400.14825880
113Sulfur metabolism_Homo sapiens_hsa009200.14045956
114Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.13403437
115Asthma_Homo sapiens_hsa053100.12466718
116Viral carcinogenesis_Homo sapiens_hsa052030.12232548
117Vitamin digestion and absorption_Homo sapiens_hsa049770.10910926
118Thyroid cancer_Homo sapiens_hsa052160.10874814
119Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.09598065
120Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.09377272
121Chemical carcinogenesis_Homo sapiens_hsa052040.09299477
122Autoimmune thyroid disease_Homo sapiens_hsa053200.08642348

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