PRTN3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1disruption of cells of other organism involved in symbiotic interaction (GO:0051818)8.67762163
2killing of cells in other organism involved in symbiotic interaction (GO:0051883)8.67762163
3neutrophil mediated immunity (GO:0002446)8.08588171
4positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)8.07175397
5regulation of MHC class II biosynthetic process (GO:0045346)7.03872384
6negative regulation of growth of symbiont in host (GO:0044130)7.03808763
7negative regulation of growth of symbiont involved in interaction with host (GO:0044146)7.03808763
8modulation of growth of symbiont involved in interaction with host (GO:0044144)7.03808763
9regulation of growth of symbiont in host (GO:0044126)7.03808763
10microglial cell activation (GO:0001774)6.92036961
11myeloid leukocyte mediated immunity (GO:0002444)6.62066509
12disruption of cells of other organism (GO:0044364)6.57022955
13killing of cells of other organism (GO:0031640)6.57022955
14positive regulation of chemokine biosynthetic process (GO:0045080)6.54597550
15defense response to fungus (GO:0050832)6.39380945
16response to fungus (GO:0009620)6.11573083
17protoporphyrinogen IX biosynthetic process (GO:0006782)6.08191063
18purine deoxyribonucleotide catabolic process (GO:0009155)5.74490929
19DNA deamination (GO:0045006)5.74485015
20ribosomal small subunit assembly (GO:0000028)5.74271029
21regulation of tumor necrosis factor biosynthetic process (GO:0042534)5.46622269
22protoporphyrinogen IX metabolic process (GO:0046501)5.27483981
23removal of superoxide radicals (GO:0019430)5.20345327
24cellular response to superoxide (GO:0071451)5.20345327
25cellular response to oxygen radical (GO:0071450)5.20345327
26macrophage chemotaxis (GO:0048246)4.91648908
27cellular response to zinc ion (GO:0071294)4.81315574
28positive regulation of interleukin-8 biosynthetic process (GO:0045416)4.75713617
29glial cell migration (GO:0008347)4.75224523
30leukocyte mediated cytotoxicity (GO:0001909)4.72736991
31telomere maintenance via semi-conservative replication (GO:0032201)4.59980717
32DNA strand elongation involved in DNA replication (GO:0006271)4.59483031
33respiratory burst (GO:0045730)4.51019358
34induction of positive chemotaxis (GO:0050930)4.50744714
35DNA strand elongation (GO:0022616)4.40620470
36reactive oxygen species biosynthetic process (GO:1903409)4.38556059
37response to superoxide (GO:0000303)4.23830142
38deoxyribonucleotide catabolic process (GO:0009264)4.21990909
39SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.21194328
40response to oxygen radical (GO:0000305)4.20900811
41pentose-phosphate shunt (GO:0006098)4.15581436
42viral transcription (GO:0019083)4.14059250
43cotranslational protein targeting to membrane (GO:0006613)4.11606795
44protein targeting to ER (GO:0045047)4.09188686
45deoxyribose phosphate catabolic process (GO:0046386)4.08970861
46base-excision repair, AP site formation (GO:0006285)4.04146436
47heme biosynthetic process (GO:0006783)4.03330132
48translational termination (GO:0006415)4.02275802
49cell wall macromolecule catabolic process (GO:0016998)3.99866026
50centriole replication (GO:0007099)3.93489831
51protein localization to endoplasmic reticulum (GO:0070972)3.91301447
52DNA replication initiation (GO:0006270)3.91014374
53establishment of protein localization to endoplasmic reticulum (GO:0072599)3.89141326
54telomere maintenance via recombination (GO:0000722)3.87990807
55NADPH regeneration (GO:0006740)3.84339541
56purine deoxyribonucleotide metabolic process (GO:0009151)3.83744797
57macrophage activation (GO:0042116)3.76812253
58translational elongation (GO:0006414)3.62146260
59DNA unwinding involved in DNA replication (GO:0006268)3.62119472
60IMP metabolic process (GO:0046040)3.48673500
61glucose 6-phosphate metabolic process (GO:0051156)3.48602532
62mitotic recombination (GO:0006312)3.47234020
63pentose metabolic process (GO:0019321)3.47002655
64Arp2/3 complex-mediated actin nucleation (GO:0034314)3.46964611
65ribosomal small subunit biogenesis (GO:0042274)3.46359841
66angiotensin maturation (GO:0002003)3.44639146
67innate immune response in mucosa (GO:0002227)3.43155598
68antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.42330820
69antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.42330820
70cell killing (GO:0001906)3.38123812
71response to food (GO:0032094)3.35680097
72inflammatory response to antigenic stimulus (GO:0002437)3.32755337
73cell wall macromolecule metabolic process (GO:0044036)3.30853705
74DNA replication checkpoint (GO:0000076)3.28772714
75porphyrin-containing compound biosynthetic process (GO:0006779)3.28367419
76regulation of interleukin-8 biosynthetic process (GO:0045414)3.28104831
77telomere maintenance via telomere lengthening (GO:0010833)3.26498621
78hydrogen peroxide metabolic process (GO:0042743)3.22351279
79positive regulation of interleukin-1 beta production (GO:0032731)3.21553332
80maturation of SSU-rRNA (GO:0030490)3.19478260
81regulation of chemokine biosynthetic process (GO:0045073)3.18644103
82negative regulation of chemokine production (GO:0032682)3.17906968
83neutrophil activation involved in immune response (GO:0002283)3.16527388
84protein localization to kinetochore (GO:0034501)3.14172895
85cellular protein complex disassembly (GO:0043624)3.10570996
86nucleobase biosynthetic process (GO:0046112)3.10496416
87translational initiation (GO:0006413)3.07882305
88nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.07830234
89interaction with symbiont (GO:0051702)3.07465277
90macrophage differentiation (GO:0030225)3.06547783
91angiogenesis involved in wound healing (GO:0060055)3.06224253
92pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.04774911
93antibacterial humoral response (GO:0019731)3.02830223
94hydrogen peroxide catabolic process (GO:0042744)3.01835503
95leukotriene biosynthetic process (GO:0019370)3.01749927
96viral life cycle (GO:0019058)2.98693636
97IMP biosynthetic process (GO:0006188)2.96974376
98GDP-mannose metabolic process (GO:0019673)2.96244149
992-deoxyribonucleotide metabolic process (GO:0009394)2.96108832
100regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.94651510
101tetrapyrrole biosynthetic process (GO:0033014)2.92356380
102pseudouridine synthesis (GO:0001522)2.91246820
103nucleotide-excision repair, DNA gap filling (GO:0006297)2.90362500
104signal peptide processing (GO:0006465)2.90345917
105negative regulation of B cell apoptotic process (GO:0002903)2.90315690
106heme metabolic process (GO:0042168)2.90235979
107centriole assembly (GO:0098534)2.89931655
108positive regulation of interleukin-1 production (GO:0032732)2.89055313
109low-density lipoprotein particle remodeling (GO:0034374)2.87765821
110deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.87582022
111positive regulation of phagocytosis (GO:0050766)2.82988996
112glucose catabolic process (GO:0006007)2.82946512
113deoxyribose phosphate metabolic process (GO:0019692)2.82225318
114protein complex disassembly (GO:0043241)2.75315201
115regulation of chemokine production (GO:0032642)2.74717232
116positive regulation of histone H3-K4 methylation (GO:0051571)2.74701898
117antimicrobial humoral response (GO:0019730)2.72289707
118modification by host of symbiont morphology or physiology (GO:0051851)2.71773563
119mannosylation (GO:0097502)2.71391554
120antigen processing and presentation of endogenous antigen (GO:0019883)2.71099118
121nucleobase-containing small molecule interconversion (GO:0015949)2.70984669
122negative regulation of granulocyte differentiation (GO:0030853)2.70656123
123necroptotic process (GO:0070266)2.69044810
124CENP-A containing nucleosome assembly (GO:0034080)2.68511362
125positive regulation of histone deacetylation (GO:0031065)2.68343927
126superoxide metabolic process (GO:0006801)2.68282744
127protein localization to chromosome, centromeric region (GO:0071459)2.67914937
128response to peptidoglycan (GO:0032494)2.66941224
129protein targeting to membrane (GO:0006612)2.66668786
130defense response to Gram-negative bacterium (GO:0050829)2.65591085
131translation (GO:0006412)2.65019949
132leukotriene metabolic process (GO:0006691)2.64643697
133mucosal immune response (GO:0002385)2.64612215
134autophagic vacuole fusion (GO:0000046)2.62930133
135ribosome assembly (GO:0042255)2.61583164
136pyrimidine nucleotide catabolic process (GO:0006244)2.60937998
137positive regulation of cytokine biosynthetic process (GO:0042108)2.60807361
138regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.60431848
139response to interferon-beta (GO:0035456)2.58910154
140chromatin remodeling at centromere (GO:0031055)2.57204742
141L-fucose catabolic process (GO:0042355)2.56821382
142fucose catabolic process (GO:0019317)2.56821382
143L-fucose metabolic process (GO:0042354)2.56821382
144macromolecular complex disassembly (GO:0032984)2.56774225
145organ or tissue specific immune response (GO:0002251)2.55741103
146purine nucleobase biosynthetic process (GO:0009113)2.55665942
147positive regulation of B cell differentiation (GO:0045579)2.54771599
1483-UTR-mediated mRNA stabilization (GO:0070935)2.53606451
149negative regulation of interleukin-8 production (GO:0032717)2.53210696
150translesion synthesis (GO:0019985)2.52878683
151deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.52219359
152formation of translation preinitiation complex (GO:0001731)2.50767835
153intra-S DNA damage checkpoint (GO:0031573)2.50505982
154antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.50169940
155cellular response to exogenous dsRNA (GO:0071360)2.50140059
156mast cell activation (GO:0045576)2.49359295
157plasma lipoprotein particle remodeling (GO:0034369)2.47667962
158protein-lipid complex remodeling (GO:0034368)2.47667962
159macromolecular complex remodeling (GO:0034367)2.47667962
160cellular extravasation (GO:0045123)11.3045597

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.61829332
2* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.92107306
3MYB_21317192_ChIP-Seq_ERMYB_Mouse3.30263059
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.29707369
5E2F4_17652178_ChIP-ChIP_JURKAT_Human2.94392123
6* VDR_21846776_ChIP-Seq_THP-1_Human2.82638877
7ELF1_17652178_ChIP-ChIP_JURKAT_Human2.79394565
8NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.77314937
9* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.72079357
10* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.68684878
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.63889377
12MYC_18358816_ChIP-ChIP_MESCs_Mouse2.50789005
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.49760309
14FOXM1_23109430_ChIP-Seq_U2OS_Human2.43263903
15GABP_17652178_ChIP-ChIP_JURKAT_Human2.41694466
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.39213046
17SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.38186483
18CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.36700941
19SCL_19346495_ChIP-Seq_HPC-7_Human2.35509936
20HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.33213559
21TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.27597070
22ETS1_20019798_ChIP-Seq_JURKAT_Human2.19666610
23MYC_19030024_ChIP-ChIP_MESCs_Mouse2.17351812
24ZNF652_21678463_ChIP-ChIP_ZR75-1_Human2.16781507
25* FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.15131312
26FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.15019982
27MYC_22102868_ChIP-Seq_BL_Human2.13943485
28NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.12331630
29* SPI1_23547873_ChIP-Seq_NB4_Human2.09090638
30* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.06814771
31EGR1_19374776_ChIP-ChIP_THP-1_Human2.01655471
32VDR_23849224_ChIP-Seq_CD4+_Human1.94245616
33MYC_19079543_ChIP-ChIP_MESCs_Mouse1.92442086
34* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.92012663
35* VDR_24763502_ChIP-Seq_THP-1_Human1.91415170
36CREB1_15753290_ChIP-ChIP_HEK293T_Human1.89133436
37CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.88166053
38SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.87644402
39HOXB4_20404135_ChIP-ChIP_EML_Mouse1.87451459
40FOXP3_21729870_ChIP-Seq_TREG_Human1.85685832
41* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.84754706
42IRF8_21731497_ChIP-ChIP_J774_Mouse1.84426939
43XRN2_22483619_ChIP-Seq_HELA_Human1.79232538
44ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.74509503
45IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.73724734
46* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.73298359
47GATA1_22025678_ChIP-Seq_K562_Human1.73193256
48ELF1_20517297_ChIP-Seq_JURKAT_Human1.73172791
49IGF1R_20145208_ChIP-Seq_DFB_Human1.68055013
50E2F1_21310950_ChIP-Seq_MCF-7_Human1.65332201
51IRF8_22096565_ChIP-ChIP_GC-B_Human1.63092595
52DCP1A_22483619_ChIP-Seq_HELA_Human1.61338425
53CIITA_25753668_ChIP-Seq_RAJI_Human1.58943233
54IKZF1_21737484_ChIP-ChIP_HCT116_Human1.58638631
55FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.57423477
56CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.56290099
57NELFA_20434984_ChIP-Seq_ESCs_Mouse1.56207128
58YY1_21170310_ChIP-Seq_MESCs_Mouse1.55179598
59* RUNX1_22412390_ChIP-Seq_EML_Mouse1.54378206
60GABP_19822575_ChIP-Seq_HepG2_Human1.52839402
61GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.50898085
62SRF_21415370_ChIP-Seq_HL-1_Mouse1.49745051
63* BCL6_27268052_Chip-Seq_Bcells_Human1.48375860
64E2F1_18555785_ChIP-Seq_MESCs_Mouse1.47823252
65* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.47790754
66LXR_22292898_ChIP-Seq_THP-1_Human1.45989680
67HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.43525751
68* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.42361353
69THAP11_20581084_ChIP-Seq_MESCs_Mouse1.40671015
70* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.40311712
71* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.39195788
72PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.39054349
73TTF2_22483619_ChIP-Seq_HELA_Human1.37960292
74MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.37523254
75MYB_26560356_Chip-Seq_TH2_Human1.35829931
76* EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.33524059
77P68_20966046_ChIP-Seq_HELA_Human1.33471029
78MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.33177014
79* STAT4_19710469_ChIP-ChIP_TH1__Mouse1.32750318
80PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.30673019
81MAF_26560356_Chip-Seq_TH2_Human1.29286240
82ZFX_18555785_ChIP-Seq_MESCs_Mouse1.28484405
83E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.28127861
84CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.27304369
85LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.27137287
86LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.23629200
87UTX_26944678_Chip-Seq_JUKART_Human1.23416958
88MAF_26560356_Chip-Seq_TH1_Human1.21946663
89AR_21909140_ChIP-Seq_LNCAP_Human1.21640526
90ELK1_19687146_ChIP-ChIP_HELA_Human1.21576896
91* TET1_21451524_ChIP-Seq_MESCs_Mouse1.21425220
92MYCN_18555785_ChIP-Seq_MESCs_Mouse1.20778451
93MYB_26560356_Chip-Seq_TH1_Human1.20566154
94MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.19055425
95BP1_19119308_ChIP-ChIP_Hs578T_Human1.17661748
96PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.15000995
97E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.13616022
98P300_27268052_Chip-Seq_Bcells_Human1.12616977
99KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.12051637
100IRF8_27001747_Chip-Seq_BMDM_Mouse1.11428116
101BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.11188886
102SPI1_20517297_ChIP-Seq_HL60_Human1.10899642
103CTCF_26484167_Chip-Seq_Bcells_Mouse1.10345159
104VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.09301951
105PHF8_20622854_ChIP-Seq_HELA_Human1.09041197
106* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.09025243
107* E2F1_20622854_ChIP-Seq_HELA_Human1.08584726
108E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.07585367
109STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.07131358
110SPI1_23127762_ChIP-Seq_K562_Human1.07102203
111* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.05887526
112POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.05769446
113RAC3_21632823_ChIP-Seq_H3396_Human1.05273091
114CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.04926893
115FOXP1_21924763_ChIP-Seq_HESCs_Human1.04827509
116* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.04461105
117STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.04287005
118ETV2_25802403_ChIP-Seq_MESCs_Mouse1.03802744
119* YY1_22570637_ChIP-Seq_MALME-3M_Human1.03599726
120TFEB_21752829_ChIP-Seq_HELA_Human1.03426339
121BCOR_27268052_Chip-Seq_Bcells_Human1.02102536
122CTCF_21964334_ChIP-Seq_BJAB-B_Human1.01637835
123RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01536142
124PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.00505705
125NOTCH1_21737748_ChIP-Seq_TLL_Human1.00098555
126KDM5A_27292631_Chip-Seq_BREAST_Human0.97747889
127CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.96795991
128CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.95690581
129IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.94860836
130FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.94238418
131GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.93359202
132FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92570642
133TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.91923223
134* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.90707737
135* PU.1_20513432_ChIP-Seq_Bcells_Mouse0.90370058
136TCF7_22412390_ChIP-Seq_EML_Mouse0.89611944

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005083_abnormal_biliary_tract4.77838186
2MP0002396_abnormal_hematopoietic_system4.35255984
3MP0003693_abnormal_embryo_hatching3.58676590
4MP0005174_abnormal_tail_pigmentation2.98214109
5MP0003303_peritoneal_inflammation2.92028502
6MP0003436_decreased_susceptibility_to2.86991441
7MP0001835_abnormal_antigen_presentation2.77690269
8MP0010094_abnormal_chromosome_stability2.77084947
9MP0009785_altered_susceptibility_to2.76266540
10MP0005670_abnormal_white_adipose2.68151423
11MP0003172_abnormal_lysosome_physiology2.61905088
12* MP0002419_abnormal_innate_immunity2.58906806
13MP0008057_abnormal_DNA_replication2.55570423
14MP0003183_abnormal_peptide_metabolism2.55188522
15MP0003724_increased_susceptibility_to2.53389288
16MP0005025_abnormal_response_to2.49594309
17MP0005464_abnormal_platelet_physiology2.45484422
18MP0000490_abnormal_crypts_of2.45169109
19MP0000465_gastrointestinal_hemorrhage2.44412334
20MP0005075_abnormal_melanosome_morpholog2.38578314
21MP0002166_altered_tumor_susceptibility2.37268596
22MP0003111_abnormal_nucleus_morphology2.30674023
23MP0005360_urolithiasis2.23350425
24MP0004957_abnormal_blastocyst_morpholog2.19502712
25MP0000569_abnormal_digit_pigmentation2.16222138
26MP0002148_abnormal_hypersensitivity_rea2.14388842
27MP0009379_abnormal_foot_pigmentation2.13207814
28MP0008961_abnormal_basal_metabolism2.13095200
29MP0004808_abnormal_hematopoietic_stem2.12559247
30MP0003077_abnormal_cell_cycle2.12336166
31MP0001545_abnormal_hematopoietic_system2.01391532
32MP0005397_hematopoietic_system_phenotyp2.01391532
33MP0008058_abnormal_DNA_repair1.96102891
34* MP0002420_abnormal_adaptive_immunity1.94440743
35MP0005000_abnormal_immune_tolerance1.91272906
36MP0002398_abnormal_bone_marrow1.90044592
37* MP0001819_abnormal_immune_cell1.89616276
38MP0001853_heart_inflammation1.87207091
39MP0002006_tumorigenesis1.80898034
40MP0000015_abnormal_ear_pigmentation1.77214674
41MP0000716_abnormal_immune_system1.77124580
42MP0002095_abnormal_skin_pigmentation1.74921408
43MP0009333_abnormal_splenocyte_physiolog1.74848096
44MP0003806_abnormal_nucleotide_metabolis1.72010522
45MP0005671_abnormal_response_to1.69769093
46MP0002452_abnormal_antigen_presenting1.68492204
47MP0000858_altered_metastatic_potential1.68402128
48MP0002723_abnormal_immune_serum1.65323882
49MP0002429_abnormal_blood_cell1.64958158
50MP0010307_abnormal_tumor_latency1.64601928
51MP0002722_abnormal_immune_system1.64128889
52MP0001986_abnormal_taste_sensitivity1.62095450
53MP0000689_abnormal_spleen_morphology1.60905185
54MP0003763_abnormal_thymus_physiology1.60426879
55MP0001800_abnormal_humoral_immune1.58353578
56MP0000685_abnormal_immune_system1.57584534
57MP0003252_abnormal_bile_duct1.54930694
58MP0004742_abnormal_vestibular_system1.54761021
59MP0001845_abnormal_inflammatory_respons1.52510639
60MP0002160_abnormal_reproductive_system1.52061016
61MP0010155_abnormal_intestine_physiology1.48110790
62MP0004043_abnormal_pH_regulation1.46580458
63MP0006054_spinal_hemorrhage1.46544675
64MP0002019_abnormal_tumor_incidence1.44019927
65MP0008007_abnormal_cellular_replicative1.43889022
66MP0002405_respiratory_system_inflammati1.41869357
67MP0001873_stomach_inflammation1.41367498
68MP0003866_abnormal_defecation1.38694063
69MP0001533_abnormal_skeleton_physiology1.35037722
70MP0004185_abnormal_adipocyte_glucose1.29762548
71MP0003186_abnormal_redox_activity1.29130566
72MP0005666_abnormal_adipose_tissue1.28504622
73MP0008995_early_reproductive_senescence1.28414940
74MP0000343_altered_response_to1.27602129
75MP0001663_abnormal_digestive_system1.20697095
76MP0005220_abnormal_exocrine_pancreas1.20529670
77MP0006036_abnormal_mitochondrial_physio1.18648063
78MP0000703_abnormal_thymus_morphology1.18607197
79MP0005058_abnormal_lysosome_morphology1.18113093
80MP0003123_paternal_imprinting1.15269178
81MP0005076_abnormal_cell_differentiation1.12535025
82MP0003656_abnormal_erythrocyte_physiolo1.11409457
83MP0005365_abnormal_bile_salt1.10246776
84MP0008469_abnormal_protein_level1.09546884
85MP0003221_abnormal_cardiomyocyte_apopto1.08624462
86MP0005451_abnormal_body_composition1.08138418
87MP0001764_abnormal_homeostasis1.04239689
88MP0005085_abnormal_gallbladder_physiolo1.02851395
89MP0005375_adipose_tissue_phenotype1.02775819
90MP0000313_abnormal_cell_death1.02612144
91MP0003786_premature_aging1.02568110
92MP0005334_abnormal_fat_pad1.01962088
93MP0005409_darkened_coat_color0.98617553
94MP0001851_eye_inflammation0.98234026
95MP0009115_abnormal_fat_cell0.96814700
96MP0008873_increased_physiological_sensi0.96164339
97MP0004147_increased_porphyrin_level0.95148305
98MP0002971_abnormal_brown_adipose0.94325080
99MP0003638_abnormal_response/metabolism_0.92779204
100MP0009764_decreased_sensitivity_to0.91050074
101MP0000358_abnormal_cell_content/0.89255641
102MP0000350_abnormal_cell_proliferation0.88675682
103MP0001790_abnormal_immune_system0.87752424
104MP0005387_immune_system_phenotype0.87752424
105MP0002970_abnormal_white_adipose0.87111762
106MP0003075_altered_response_to0.87081749
107MP0008260_abnormal_autophagy0.84009667
108MP0008932_abnormal_embryonic_tissue0.82926512
109MP0005164_abnormal_response_to0.82308597
110MP0000003_abnormal_adipose_tissue0.80984331
111MP0005389_reproductive_system_phenotype0.79733524
112MP0009643_abnormal_urine_homeostasis0.78758528
113MP0009763_increased_sensitivity_to0.78354018
114MP0003300_gastrointestinal_ulcer0.76441576
115MP0008872_abnormal_physiological_respon0.75996761
116MP0000249_abnormal_blood_vessel0.75669610
117MP0004264_abnormal_extraembryonic_tissu0.75175141
118MP0008874_decreased_physiological_sensi0.75017440
119MP0004782_abnormal_surfactant_physiolog0.74743394
120MP0002877_abnormal_melanocyte_morpholog0.73486267
121MP0010329_abnormal_lipoprotein_level0.73437202
122MP0006082_CNS_inflammation0.71807945
123MP0003191_abnormal_cellular_cholesterol0.71424664
124MP0000371_diluted_coat_color0.71375068
125MP0008877_abnormal_DNA_methylation0.69284239
126MP0001905_abnormal_dopamine_level0.66829066
127MP0009278_abnormal_bone_marrow0.66775921
128MP0005266_abnormal_metabolism0.64302577
129MP0001730_embryonic_growth_arrest0.63485474
130MP0005376_homeostasis/metabolism_phenot0.61536713
131MP0005381_digestive/alimentary_phenotyp0.60503639
132MP0010352_gastrointestinal_tract_polyps0.60048918
133MP0005584_abnormal_enzyme/coenzyme_acti0.58481406
134MP0002075_abnormal_coat/hair_pigmentati0.58461772
135MP0003448_altered_tumor_morphology0.57982525
136MP0000598_abnormal_liver_morphology0.57815415
137MP0005319_abnormal_enzyme/_coenzyme0.56161641

Predicted human phenotypes

RankGene SetZ-score
1Thrombocytosis (HP:0001894)8.11065163
2Reduced antithrombin III activity (HP:0001976)5.16897674
3Abnormal number of erythroid precursors (HP:0012131)4.92635427
4Abnormality of cells of the erythroid lineage (HP:0012130)4.81318572
5Type I transferrin isoform profile (HP:0003642)4.54775525
6Recurrent abscess formation (HP:0002722)4.44167291
7Reticulocytopenia (HP:0001896)4.39527699
8Elevated erythrocyte sedimentation rate (HP:0003565)4.39263603
9Recurrent bacterial skin infections (HP:0005406)4.17393127
10Aplastic anemia (HP:0001915)4.16826025
11Periodontitis (HP:0000704)3.95725739
12Myositis (HP:0100614)3.90909081
13Eczematoid dermatitis (HP:0000976)3.90155724
14Abnormal protein glycosylation (HP:0012346)3.64071849
15Abnormal glycosylation (HP:0012345)3.64071849
16Abnormal isoelectric focusing of serum transferrin (HP:0003160)3.64071849
17Abnormal protein N-linked glycosylation (HP:0012347)3.64071849
18Agammaglobulinemia (HP:0004432)3.63501107
19IgM deficiency (HP:0002850)3.60319874
20Eosinophilia (HP:0001880)3.47760288
21Granulocytopenia (HP:0001913)3.44371917
22Increased neuronal autofluorescent lipopigment (HP:0002074)3.36623010
23Petechiae (HP:0000967)3.27147706
24Papilledema (HP:0001085)3.16843593
25B lymphocytopenia (HP:0010976)3.03983709
26Abnormality of B cell number (HP:0010975)3.03983709
27Chronic otitis media (HP:0000389)3.02062776
28Abnormality of the heme biosynthetic pathway (HP:0010472)2.99526067
29Hepatosplenomegaly (HP:0001433)2.97271942
30Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.96377410
31Abnormality of T cell physiology (HP:0011840)2.92354807
32Poikiloderma (HP:0001029)2.82510243
33Oral leukoplakia (HP:0002745)2.76549113
34Tubulointerstitial nephritis (HP:0001970)2.76139369
35Increased cerebral lipofuscin (HP:0011813)2.75668909
36Recurrent gram-negative bacterial infections (HP:0005420)2.75460091
37Renal Fanconi syndrome (HP:0001994)2.74204770
38Recurrent skin infections (HP:0001581)2.70439877
39Progressive microcephaly (HP:0000253)2.67372806
40Hypergammaglobulinemia (HP:0010702)2.66952747
41Mediastinal lymphadenopathy (HP:0100721)2.66252946
42Abnormality of the thoracic spine (HP:0100711)2.62891048
43Neutropenia (HP:0001875)2.62756563
44Thoracic kyphosis (HP:0002942)2.60010650
45* Obstructive lung disease (HP:0006536)2.58366393
46* Chronic obstructive pulmonary disease (HP:0006510)2.58366393
47Amyloidosis (HP:0011034)2.54510543
48Duplicated collecting system (HP:0000081)2.53298975
49Abnormality of eosinophils (HP:0001879)2.52398535
50Rhabdomyolysis (HP:0003201)2.51622190
51Macrocytic anemia (HP:0001972)2.50799182
52* Meningitis (HP:0001287)2.49115050
53Impaired platelet aggregation (HP:0003540)2.44154866
54Abnormal platelet function (HP:0011869)2.44154866
55J-shaped sella turcica (HP:0002680)2.40448720
56Leukocytosis (HP:0001974)2.40294413
57Pancytopenia (HP:0001876)2.38761888
58Cutaneous photosensitivity (HP:0000992)2.37992742
59Prolonged bleeding time (HP:0003010)2.37186207
60Mitochondrial inheritance (HP:0001427)2.36763683
61Abnormality of macrophages (HP:0004311)2.36711729
62Hepatic necrosis (HP:0002605)2.34787208
63Pallor (HP:0000980)2.34381155
64Myelodysplasia (HP:0002863)2.32612611
65Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.32122686
66Chronic mucocutaneous candidiasis (HP:0002728)2.31783095
67Recurrent cutaneous fungal infections (HP:0011370)2.31783095
68Severe visual impairment (HP:0001141)2.30435699
69Cellulitis (HP:0100658)2.27659207
70Recurrent fungal infections (HP:0002841)2.25662536
71Amaurosis fugax (HP:0100576)2.25314135
72Bone marrow hypocellularity (HP:0005528)2.23895821
73Agnosia (HP:0010524)2.23550629
74Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.22274276
75Recurrent viral infections (HP:0004429)2.21691510
7611 pairs of ribs (HP:0000878)2.21310044
77Microvesicular hepatic steatosis (HP:0001414)2.21258089
78Abnormality of DNA repair (HP:0003254)2.20437869
79Acute myeloid leukemia (HP:0004808)2.20157827
80Panhypogammaglobulinemia (HP:0003139)2.17392905
81Generalized aminoaciduria (HP:0002909)2.17349406
82Loss of speech (HP:0002371)2.16765533
83* Skin rash (HP:0000988)2.14122969
84Entropion (HP:0000621)2.13157485
85Albinism (HP:0001022)2.13037044
86Abnormality of the renal collecting system (HP:0004742)2.12778624
87Chromsome breakage (HP:0040012)2.12601272
88Increased serum ferritin (HP:0003281)2.12455182
89Orchitis (HP:0100796)2.10752770
90Hepatocellular necrosis (HP:0001404)2.08905313
91Sepsis (HP:0100806)2.08714822
92Porencephaly (HP:0002132)2.07977806
93Cleft eyelid (HP:0000625)2.06787212
94Vacuolated lymphocytes (HP:0001922)2.06545123
95Abnormal delayed hypersensitivity skin test (HP:0002963)2.03789235
96Exertional dyspnea (HP:0002875)2.03419465
97Birth length less than 3rd percentile (HP:0003561)2.03110699
98Increased CSF lactate (HP:0002490)2.02133690
99Ocular albinism (HP:0001107)2.01881078
100Increased hepatocellular lipid droplets (HP:0006565)2.01428484
101Poor head control (HP:0002421)2.01349779
102* Epistaxis (HP:0000421)1.98874761
103Visual hallucinations (HP:0002367)1.98143366
104Abnormality of dicarboxylic acid metabolism (HP:0010995)1.97186558
105Dicarboxylic aciduria (HP:0003215)1.97186558
106* Chest pain (HP:0100749)1.95802431
107Abnormality of iron homeostasis (HP:0011031)1.94748423
108Paralysis (HP:0003470)1.93860261
109Abnormality of liposaccharide metabolism (HP:0010968)1.93058082
110Abnormality of glycosphingolipid metabolism (HP:0004343)1.93058082
111Abnormality of glycolipid metabolism (HP:0010969)1.93058082
112Lipid accumulation in hepatocytes (HP:0006561)1.92352679
113Severe global developmental delay (HP:0011344)1.92143294
114Hypergonadotropic hypogonadism (HP:0000815)1.91089352
115Annular pancreas (HP:0001734)1.90320004
116Premature graying of hair (HP:0002216)1.89311285
117Abnormality of the lumbar spine (HP:0100712)1.87972766
118Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.87891444
119Ragged-red muscle fibers (HP:0003200)1.87875177
120Abnormality of transition element cation homeostasis (HP:0011030)1.87850634
121Abnormality of lateral ventricle (HP:0030047)1.87825427
122Abnormality of cells of the lymphoid lineage (HP:0012140)1.87192066
123Lymphoma (HP:0002665)1.86934514
124Hypertensive crisis (HP:0100735)1.86776537
125Abnormality of chromosome stability (HP:0003220)1.86131439
126Gingivitis (HP:0000230)1.86038597
127Osteomyelitis (HP:0002754)1.85694108
128Dysostosis multiplex (HP:0000943)1.85341124
129Increased intramyocellular lipid droplets (HP:0012240)1.83651203
130Degeneration of anterior horn cells (HP:0002398)1.83294835
131Abnormality of the anterior horn cell (HP:0006802)1.83294835
132Ureteral duplication (HP:0000073)1.83195448
133Gastrointestinal infarctions (HP:0005244)1.82775961
134Acute lymphatic leukemia (HP:0006721)1.82524663
135* Skin ulcer (HP:0200042)1.82416954
136Progressive muscle weakness (HP:0003323)1.81832152
137Chromosomal breakage induced by crosslinking agents (HP:0003221)1.81752223
138Lymphopenia (HP:0001888)1.81435006
139Spontaneous hematomas (HP:0007420)1.80692191
140Abnormality of pyrimidine metabolism (HP:0004353)1.80379460
141Abnormality of renal resorption (HP:0011038)1.80121259
142Increased muscle lipid content (HP:0009058)1.79324991
143Abnormality of T cells (HP:0002843)1.78530821
144Stomatitis (HP:0010280)1.78516332
145Respiratory difficulties (HP:0002880)1.78272755
146Abnormality of the columella (HP:0009929)1.78033478
147Microretrognathia (HP:0000308)1.77753745

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK24.39570724
2EIF2AK34.35522056
3STK164.17602279
4IRAK43.35544672
5WEE12.77483756
6TEC2.49970258
7TNK22.39903701
8FES2.29660314
9MAP3K122.26484507
10PIM22.18768633
11CDC72.12338010
12BTK2.11374115
13NUAK12.08658368
14BUB12.07576558
15EEF2K2.07357060
16ARAF2.03282205
17TAOK32.01472023
18VRK12.01135820
19BLK1.92494433
20FLT31.90171992
21MAP4K11.88430420
22ERN11.81035592
23MAP4K21.80042057
24TESK21.75253046
25MAP2K31.71739377
26SMG11.68987341
27KIT1.67389261
28CAMKK21.63100931
29PKN21.61770388
30TNIK1.58114672
31CAMK1D1.51082957
32SCYL21.49868471
33EIF2AK11.45217954
34TAF11.43896612
35CDK121.42030645
36BRSK21.38526322
37CDK191.29283793
38RIPK41.26932165
39TESK11.25075826
40SYK1.24736629
41MKNK11.23482349
42NME21.22202787
43RPS6KB21.22176774
44CDK81.18845251
45ACVR1B1.18786810
46ATR1.15623938
47EIF2AK21.14323789
48SRPK11.14019838
49PAK41.12987195
50DAPK11.12406351
51CDK71.06702905
52NEK21.06543761
53TSSK61.02633436
54ZAP701.02560997
55MKNK21.02312309
56MAP3K60.97181684
57GRK70.96169255
58IRAK30.93803739
59KDR0.92132246
60MAPK40.91426431
61LRRK20.91262841
62ICK0.90594104
63GRK50.89693936
64TGFBR10.89188297
65MYLK0.87524248
66PIM10.84160649
67CLK10.84136098
68BCKDK0.83825684
69CSF1R0.83294907
70CDK40.81896448
71PASK0.81803457
72DYRK30.81040544
73ABL20.79339973
74LYN0.78976912
75GRK60.78569544
76BRAF0.78456185
77RPS6KL10.78219914
78RPS6KC10.78219914
79MAPKAPK30.78078045
80TYK20.77753494
81RPS6KA60.76484592
82MAP3K80.76251042
83AURKB0.74413549
84PLK40.74073043
85HIPK20.72604256
86RAF10.72008307
87CDK60.71179386
88MATK0.69506710
89CAMK1G0.68281275
90CCNB10.67834749
91ILK0.67365933
92CAMK10.67105208
93ITK0.66944714
94MAP3K70.66275289
95MOS0.64676212
96BRSK10.64399532
97MAP3K110.64159709
98PLK10.61592271
99RPS6KA20.57953052
100JAK30.56807772
101HCK0.56343965
102TRIM280.56077139
103CDK90.56054975
104LIMK10.55156384
105TRPM70.53062030
106LCK0.50684466
107TGFBR20.50490206
108PIK3CG0.48352342
109IKBKE0.47861615
110RPS6KB10.47608807
111RPS6KA50.47605511
112TXK0.45790566
113PAK10.44832237
114MAPKAPK50.44573385
115CHEK10.43714793
116RPS6KA40.43178348
117STK40.43014571
118TLK10.42592719
119MAP2K60.42555336
120CSNK2A20.41673951
121MAPK110.41236533
122CDK30.40875091
123DYRK20.40179438
124DAPK20.39649479
125PDK10.39492546
126IKBKB0.39130765
127TBK10.39127706
128CHEK20.38866140
129CAMKK10.38089458
130MARK20.37610872
131PDPK10.37588119
132CSNK2A10.37002009
133ADRBK10.35452187
134PAK20.33080122
135INSRR0.29185974
136AKT10.29162004
137PRKCQ0.28179600
138PRKCD0.26453145
139MAP2K20.25744616

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.33895137
2Ribosome_Homo sapiens_hsa030103.93294141
3Mismatch repair_Homo sapiens_hsa034303.44488139
4Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.06723836
5Base excision repair_Homo sapiens_hsa034102.95838570
6Protein export_Homo sapiens_hsa030602.94876826
7Homologous recombination_Homo sapiens_hsa034402.72862799
8N-Glycan biosynthesis_Homo sapiens_hsa005102.60983240
9Pentose phosphate pathway_Homo sapiens_hsa000302.31640857
10Oxidative phosphorylation_Homo sapiens_hsa001902.25456316
11Nucleotide excision repair_Homo sapiens_hsa034202.13075321
12Spliceosome_Homo sapiens_hsa030402.03878117
13Proteasome_Homo sapiens_hsa030502.02483491
14Renin-angiotensin system_Homo sapiens_hsa046142.00337778
15Pyrimidine metabolism_Homo sapiens_hsa002401.87909492
16Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.85926009
17Other glycan degradation_Homo sapiens_hsa005111.79756898
18Fanconi anemia pathway_Homo sapiens_hsa034601.72898623
19Non-homologous end-joining_Homo sapiens_hsa034501.68292803
20Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.66045856
21One carbon pool by folate_Homo sapiens_hsa006701.64556985
22Leishmaniasis_Homo sapiens_hsa051401.52863981
23Cell cycle_Homo sapiens_hsa041101.52459588
24RNA polymerase_Homo sapiens_hsa030201.48812309
25Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.44029275
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.43007722
27RNA transport_Homo sapiens_hsa030131.42492767
28Galactose metabolism_Homo sapiens_hsa000521.38790952
29Huntingtons disease_Homo sapiens_hsa050161.36718335
30Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.35711295
31Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.30499787
32Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.28023461
33Staphylococcus aureus infection_Homo sapiens_hsa051501.27423168
34Glycosaminoglycan degradation_Homo sapiens_hsa005311.24639533
35Antigen processing and presentation_Homo sapiens_hsa046121.23867395
36Glutathione metabolism_Homo sapiens_hsa004801.20316606
37RNA degradation_Homo sapiens_hsa030181.20271208
38Systemic lupus erythematosus_Homo sapiens_hsa053221.14520780
39Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.14162608
40Alzheimers disease_Homo sapiens_hsa050101.06402244
41Purine metabolism_Homo sapiens_hsa002301.06154363
42Asthma_Homo sapiens_hsa053101.03660681
43Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.00960239
44Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.00185145
45RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.97702858
46Tryptophan metabolism_Homo sapiens_hsa003800.97665391
47Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.93083633
48Herpes simplex infection_Homo sapiens_hsa051680.92406120
49Sulfur relay system_Homo sapiens_hsa041220.91269369
50Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.86477704
51Amoebiasis_Homo sapiens_hsa051460.86389129
52Legionellosis_Homo sapiens_hsa051340.85316877
53Primary immunodeficiency_Homo sapiens_hsa053400.85070691
54Peroxisome_Homo sapiens_hsa041460.83646226
55SNARE interactions in vesicular transport_Homo sapiens_hsa041300.82534058
56Drug metabolism - other enzymes_Homo sapiens_hsa009830.81188140
57Transcriptional misregulation in cancer_Homo sapiens_hsa052020.81157439
58Biosynthesis of amino acids_Homo sapiens_hsa012300.81099687
59Starch and sucrose metabolism_Homo sapiens_hsa005000.80674731
60Glycerophospholipid metabolism_Homo sapiens_hsa005640.79898662
61Regulation of autophagy_Homo sapiens_hsa041400.79678779
62NOD-like receptor signaling pathway_Homo sapiens_hsa046210.79628154
63Cardiac muscle contraction_Homo sapiens_hsa042600.76713415
64Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.74370329
65Phagosome_Homo sapiens_hsa041450.73135505
66Pertussis_Homo sapiens_hsa051330.72788815
67Carbon metabolism_Homo sapiens_hsa012000.72540488
68Fructose and mannose metabolism_Homo sapiens_hsa000510.72249970
69Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.71665329
70Phenylalanine metabolism_Homo sapiens_hsa003600.67024451
71Lysosome_Homo sapiens_hsa041420.66980193
72Intestinal immune network for IgA production_Homo sapiens_hsa046720.65812883
73Osteoclast differentiation_Homo sapiens_hsa043800.65359724
74p53 signaling pathway_Homo sapiens_hsa041150.61770231
75Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.61096367
76Basal transcription factors_Homo sapiens_hsa030220.60243376
77Measles_Homo sapiens_hsa051620.59569619
78Thyroid cancer_Homo sapiens_hsa052160.59437079
79Folate biosynthesis_Homo sapiens_hsa007900.58998549
80Cysteine and methionine metabolism_Homo sapiens_hsa002700.58591927
81Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.58462991
82Glycerolipid metabolism_Homo sapiens_hsa005610.57965275
83B cell receptor signaling pathway_Homo sapiens_hsa046620.57891883
84Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.56814379
85Malaria_Homo sapiens_hsa051440.55252465
86Epstein-Barr virus infection_Homo sapiens_hsa051690.54971846
87Apoptosis_Homo sapiens_hsa042100.54662859
88Pyruvate metabolism_Homo sapiens_hsa006200.53994592
89Non-small cell lung cancer_Homo sapiens_hsa052230.53402135
90Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.53367677
91Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.53204698
92Shigellosis_Homo sapiens_hsa051310.52112610
93Tyrosine metabolism_Homo sapiens_hsa003500.52084589
94Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.50764008
95Acute myeloid leukemia_Homo sapiens_hsa052210.49671936
96Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.49570570
97Steroid hormone biosynthesis_Homo sapiens_hsa001400.47815093
98Ether lipid metabolism_Homo sapiens_hsa005650.45876218
99Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.45336354
100NF-kappa B signaling pathway_Homo sapiens_hsa040640.44975804
101Tuberculosis_Homo sapiens_hsa051520.44920113
102Sulfur metabolism_Homo sapiens_hsa009200.43806740
103Toll-like receptor signaling pathway_Homo sapiens_hsa046200.43566363
104Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.42247540
105Influenza A_Homo sapiens_hsa051640.41995995
106Hepatitis B_Homo sapiens_hsa051610.41341120
107Leukocyte transendothelial migration_Homo sapiens_hsa046700.41319562
1082-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.41147667
109Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.40337310
110Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.38929651
111Selenocompound metabolism_Homo sapiens_hsa004500.38362562
112Platelet activation_Homo sapiens_hsa046110.38267426
113Carbohydrate digestion and absorption_Homo sapiens_hsa049730.37889232
114Autoimmune thyroid disease_Homo sapiens_hsa053200.37637568
115Fatty acid degradation_Homo sapiens_hsa000710.37550861
116Salmonella infection_Homo sapiens_hsa051320.37481868
117Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.36557335
118Cyanoamino acid metabolism_Homo sapiens_hsa004600.35105610
119Metabolic pathways_Homo sapiens_hsa011000.34562960
120Allograft rejection_Homo sapiens_hsa053300.33632440
121Rheumatoid arthritis_Homo sapiens_hsa053230.33586396
122Parkinsons disease_Homo sapiens_hsa050120.32774542
123Phototransduction_Homo sapiens_hsa047440.31868394
124Arachidonic acid metabolism_Homo sapiens_hsa005900.31498737
125Hematopoietic cell lineage_Homo sapiens_hsa046400.31458468
126African trypanosomiasis_Homo sapiens_hsa051430.30858543
127Salivary secretion_Homo sapiens_hsa049700.30063339
128Viral carcinogenesis_Homo sapiens_hsa052030.29906999
129Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29728640
130Graft-versus-host disease_Homo sapiens_hsa053320.29392992
131VEGF signaling pathway_Homo sapiens_hsa043700.27771473
132Propanoate metabolism_Homo sapiens_hsa006400.27681389
133Neurotrophin signaling pathway_Homo sapiens_hsa047220.26488788
134Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.25956301
135Caffeine metabolism_Homo sapiens_hsa002320.25176118
136Fatty acid elongation_Homo sapiens_hsa000620.23277709

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