PRPF38A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic metaphase plate congression (GO:0007080)5.05876302
2metaphase plate congression (GO:0051310)4.48075149
3CENP-A containing nucleosome assembly (GO:0034080)4.21746506
4kinetochore organization (GO:0051383)4.17911726
5chromatin remodeling at centromere (GO:0031055)4.12923393
6protein localization to kinetochore (GO:0034501)4.12545600
7DNA strand elongation involved in DNA replication (GO:0006271)4.08704976
8establishment of chromosome localization (GO:0051303)4.07056726
9DNA replication checkpoint (GO:0000076)3.98899925
10DNA replication initiation (GO:0006270)3.94953004
11kinetochore assembly (GO:0051382)3.94820318
12DNA strand elongation (GO:0022616)3.90416490
13telomere maintenance via semi-conservative replication (GO:0032201)3.88610466
14DNA replication-independent nucleosome organization (GO:0034724)3.82414865
15DNA replication-independent nucleosome assembly (GO:0006336)3.82414865
16attachment of spindle microtubules to kinetochore (GO:0008608)3.79362568
17DNA ligation (GO:0006266)3.78795715
18maturation of SSU-rRNA (GO:0030490)3.77923744
19telomere maintenance via recombination (GO:0000722)3.72795289
20protein-cofactor linkage (GO:0018065)3.66755210
21DNA topological change (GO:0006265)3.63448789
22histone exchange (GO:0043486)3.61504266
23protein localization to chromosome, centromeric region (GO:0071459)3.61249197
24nucleobase biosynthetic process (GO:0046112)3.59381599
25DNA double-strand break processing (GO:0000729)3.57082794
26mitotic recombination (GO:0006312)3.56251590
27regulation of mitotic spindle checkpoint (GO:1903504)3.54670195
28regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.54670195
29formation of translation preinitiation complex (GO:0001731)3.53706324
30nuclear pore organization (GO:0006999)3.53587563
31DNA replication-dependent nucleosome assembly (GO:0006335)3.53341483
32DNA replication-dependent nucleosome organization (GO:0034723)3.53341483
33mitotic nuclear envelope disassembly (GO:0007077)3.52458854
34purine nucleobase biosynthetic process (GO:0009113)3.50885377
35spindle checkpoint (GO:0031577)3.49588164
36ribosomal large subunit biogenesis (GO:0042273)3.49045464
37ribosome assembly (GO:0042255)3.48677484
38meiotic chromosome segregation (GO:0045132)3.45722101
39somatic diversification of immune receptors via somatic mutation (GO:0002566)3.44326043
40somatic hypermutation of immunoglobulin genes (GO:0016446)3.44326043
41regulation of spindle organization (GO:0090224)3.43376471
42spliceosomal snRNP assembly (GO:0000387)3.42532629
437-methylguanosine mRNA capping (GO:0006370)3.41982916
44anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.41578059
45RNA capping (GO:0036260)3.40286246
467-methylguanosine RNA capping (GO:0009452)3.40286246
47DNA unwinding involved in DNA replication (GO:0006268)3.38290661
48proteasome assembly (GO:0043248)3.36940994
49mitotic chromosome condensation (GO:0007076)3.34969141
50mitotic sister chromatid segregation (GO:0000070)3.34852719
51exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.34772169
52ribosomal small subunit assembly (GO:0000028)3.34380549
53negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.33753171
54regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.33249018
55positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.32956349
56negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.32769057
57negative regulation of sister chromatid segregation (GO:0033046)3.32769057
58negative regulation of mitotic sister chromatid separation (GO:2000816)3.32769057
59negative regulation of mitotic sister chromatid segregation (GO:0033048)3.32769057
60telomere maintenance via telomere lengthening (GO:0010833)3.32738497
61transcription-coupled nucleotide-excision repair (GO:0006283)3.31093113
62nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.30754638
63spindle assembly checkpoint (GO:0071173)3.30683441
64negative regulation of chromosome segregation (GO:0051985)3.29985645
65regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.28524010
66nuclear pore complex assembly (GO:0051292)3.27403927
67mitotic spindle assembly checkpoint (GO:0007094)3.26849548
68nucleotide-excision repair, DNA gap filling (GO:0006297)3.26540111
69regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.25653093
70ribosome biogenesis (GO:0042254)3.25175537
71mitotic spindle checkpoint (GO:0071174)3.24078946
72regulation of mitotic metaphase/anaphase transition (GO:0030071)3.23877791
73negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.23816822
74membrane disassembly (GO:0030397)3.21536800
75nuclear envelope disassembly (GO:0051081)3.21536800
76ribonucleoprotein complex biogenesis (GO:0022613)3.19957796
77double-strand break repair via nonhomologous end joining (GO:0006303)3.19509645
78non-recombinational repair (GO:0000726)3.19509645
79negative regulation of DNA-dependent DNA replication (GO:2000104)3.18669592
80replication fork processing (GO:0031297)3.17916327
81regulation of chromosome segregation (GO:0051983)3.17833336
82establishment of integrated proviral latency (GO:0075713)3.17442763
83regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.17162230
84somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.16666650
85somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.16666650
86isotype switching (GO:0045190)3.16666650
87spliceosomal complex assembly (GO:0000245)3.15470275
88establishment of protein localization to mitochondrial membrane (GO:0090151)3.10840923
89DNA catabolic process, exonucleolytic (GO:0000738)3.09713382
90protein K6-linked ubiquitination (GO:0085020)3.09005443
91rRNA modification (GO:0000154)3.08802907
92transcription elongation from RNA polymerase I promoter (GO:0006362)3.08257462
93regulation of sister chromatid segregation (GO:0033045)3.07886102
94regulation of mitotic sister chromatid separation (GO:0010965)3.07886102
95regulation of mitotic sister chromatid segregation (GO:0033047)3.07886102
96termination of RNA polymerase I transcription (GO:0006363)3.07725002
97mismatch repair (GO:0006298)3.07461100
98mitotic sister chromatid cohesion (GO:0007064)3.06490780
99mitochondrial RNA metabolic process (GO:0000959)3.05154127
100RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.04901812
101positive regulation of chromosome segregation (GO:0051984)3.04395051
102rRNA processing (GO:0006364)3.03850227
103maturation of 5.8S rRNA (GO:0000460)3.02243677
104regulation of centrosome cycle (GO:0046605)3.01720094
105negative regulation of ligase activity (GO:0051352)3.01642613
106negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.01642613
107viral mRNA export from host cell nucleus (GO:0046784)3.01439806
108transcription elongation from RNA polymerase III promoter (GO:0006385)3.01057105
109termination of RNA polymerase III transcription (GO:0006386)3.01057105
110mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.00469369
111chromosome segregation (GO:0007059)3.00138801
112sister chromatid segregation (GO:0000819)2.99833411
113rRNA metabolic process (GO:0016072)2.98318773
114IMP biosynthetic process (GO:0006188)2.97847883
115protein neddylation (GO:0045116)2.97819367
116regulation of nuclear cell cycle DNA replication (GO:0033262)2.97623964
117positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.97460260
118microtubule depolymerization (GO:0007019)2.96242133
119DNA damage response, detection of DNA damage (GO:0042769)2.95741929
120cullin deneddylation (GO:0010388)2.95432633
121rRNA methylation (GO:0031167)2.92758668
122regulation of helicase activity (GO:0051095)2.92627313
123regulation of DNA endoreduplication (GO:0032875)2.92295233
124histone H2A acetylation (GO:0043968)2.92015961
125regulation of mitotic spindle organization (GO:0060236)2.92005923
126regulation of centriole replication (GO:0046599)2.91552416
127cell cycle G1/S phase transition (GO:0044843)2.91543096
128G1/S transition of mitotic cell cycle (GO:0000082)2.91543096
129protein deneddylation (GO:0000338)2.91494922
130chaperone-mediated protein transport (GO:0072321)2.91464982
131regulation of double-strand break repair via homologous recombination (GO:0010569)2.90850914
132maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.89495669
133postreplication repair (GO:0006301)2.88646615
134intra-S DNA damage checkpoint (GO:0031573)2.88568622
135negative regulation of DNA recombination (GO:0045910)2.88309528
136transcription from RNA polymerase I promoter (GO:0006360)2.87030166
137protein localization to chromosome (GO:0034502)2.86358911
138somatic diversification of immune receptors via germline recombination within a single locus (GO:0002.85249252
139somatic cell DNA recombination (GO:0016444)2.85249252
140histone mRNA metabolic process (GO:0008334)2.84801100
141somatic diversification of immune receptors (GO:0002200)2.84443865
142termination of RNA polymerase II transcription (GO:0006369)2.84088905
143synapsis (GO:0007129)2.83572861
144somatic recombination of immunoglobulin gene segments (GO:0016447)2.82964855
145somatic diversification of immunoglobulins (GO:0016445)2.82113288

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.41704698
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.31584210
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.10116086
4E2F4_17652178_ChIP-ChIP_JURKAT_Human4.09208182
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.74815529
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.45774897
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.34968586
8GABP_17652178_ChIP-ChIP_JURKAT_Human3.25507442
9CREB1_15753290_ChIP-ChIP_HEK293T_Human2.94981858
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.94207781
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.89875528
12MYC_19079543_ChIP-ChIP_MESCs_Mouse2.89098361
13* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.88763959
14MYC_19030024_ChIP-ChIP_MESCs_Mouse2.80019927
15CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.72190572
16* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.63940841
17MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.55532650
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.48824167
19VDR_23849224_ChIP-Seq_CD4+_Human2.47961978
20* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.41379617
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.28594572
22E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.28480946
23* XRN2_22483619_ChIP-Seq_HELA_Human2.27967445
24MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.20051869
25ELF1_17652178_ChIP-ChIP_JURKAT_Human2.17090534
26ELK1_19687146_ChIP-ChIP_HELA_Human2.16971539
27* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.14885538
28FOXP3_21729870_ChIP-Seq_TREG_Human2.10431467
29* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.09156422
30AR_21909140_ChIP-Seq_LNCAP_Human2.07306727
31E2F1_21310950_ChIP-Seq_MCF-7_Human2.02316349
32DCP1A_22483619_ChIP-Seq_HELA_Human2.00367302
33PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.99142890
34MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.98209133
35E2F1_18555785_ChIP-Seq_MESCs_Mouse1.97721818
36HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.97283930
37* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.92160988
38* TTF2_22483619_ChIP-Seq_HELA_Human1.82990024
39* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.82972205
40ZNF274_21170338_ChIP-Seq_K562_Hela1.82275044
41SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.81305059
42POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.80682829
43NANOG_18555785_ChIP-Seq_MESCs_Mouse1.79159203
44EWS_26573619_Chip-Seq_HEK293_Human1.78919126
45GABP_19822575_ChIP-Seq_HepG2_Human1.77330497
46THAP11_20581084_ChIP-Seq_MESCs_Mouse1.75506803
47CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.73908304
48FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.73820460
49HOXB4_20404135_ChIP-ChIP_EML_Mouse1.70021390
50TP63_19390658_ChIP-ChIP_HaCaT_Human1.67408141
51YY1_21170310_ChIP-Seq_MESCs_Mouse1.64954777
52SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.64515084
53ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.60916598
54* SRF_21415370_ChIP-Seq_HL-1_Mouse1.60123054
55FUS_26573619_Chip-Seq_HEK293_Human1.49927180
56CIITA_25753668_ChIP-Seq_RAJI_Human1.46121393
57EGR1_19374776_ChIP-ChIP_THP-1_Human1.45947785
58IGF1R_20145208_ChIP-Seq_DFB_Human1.45018681
59* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.39789617
60PADI4_21655091_ChIP-ChIP_MCF-7_Human1.37821699
61SALL1_21062744_ChIP-ChIP_HESCs_Human1.36213357
62KDM5A_27292631_Chip-Seq_BREAST_Human1.33372750
63RBPJ_22232070_ChIP-Seq_NCS_Mouse1.32970021
64ZFX_18555785_ChIP-Seq_MESCs_Mouse1.29049867
65POU3F2_20337985_ChIP-ChIP_501MEL_Human1.25271394
66TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.23504578
67SOX2_18555785_ChIP-Seq_MESCs_Mouse1.22115016
68TAF15_26573619_Chip-Seq_HEK293_Human1.19633827
69* PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.18956612
70* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.18618800
71SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.15994393
72MYC_18940864_ChIP-ChIP_HL60_Human1.15954350
73CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.15764115
74SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.15441348
75VDR_22108803_ChIP-Seq_LS180_Human1.13672033
76ERG_20887958_ChIP-Seq_HPC-7_Mouse1.13386952
77IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.12764339
78CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.12138036
79FLI1_27457419_Chip-Seq_LIVER_Mouse1.10024723
80FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.09886197
81ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.07865526
82* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.06577027
83KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.05014470
84TFEB_21752829_ChIP-Seq_HELA_Human1.04160485
85ELK1_22589737_ChIP-Seq_MCF10A_Human1.01420269
86NOTCH1_21737748_ChIP-Seq_TLL_Human0.98897563
87POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.98139363
88SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.97636846
89IRF8_21731497_ChIP-ChIP_J774_Mouse0.94392616
90SPI1_23547873_ChIP-Seq_NB4_Human0.90135918
91* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.90124504
92BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.90018137
93STAT3_1855785_ChIP-Seq_MESCs_Mouse0.88654529
94KLF4_18555785_ChIP-Seq_MESCs_Mouse0.88203926
95CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.87289540
96TP53_22573176_ChIP-Seq_HFKS_Human0.86399304
97MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.85709120
98NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.85304622
99PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.82511843
100KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.80577331
101KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.80577331
102KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.80577331
103SOX17_20123909_ChIP-Seq_XEN_Mouse0.80470488
104NANOG_21062744_ChIP-ChIP_HESCs_Human0.79484724
105NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.79020091
106NANOG_16153702_ChIP-ChIP_HESCs_Human0.78893686
107SOX2_16153702_ChIP-ChIP_HESCs_Human0.78592592
108TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.78406863
109POU5F1_16153702_ChIP-ChIP_HESCs_Human0.78255849
110CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.78149081
111GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.77928888
112GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.77860256
113IRF1_19129219_ChIP-ChIP_H3396_Human0.76589273
114PCGF2_27294783_Chip-Seq_ESCs_Mouse0.74501210
115SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.73536448
116ZFP57_27257070_Chip-Seq_ESCs_Mouse0.72224489
117GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.70003552
118EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.69835292
119P300_19829295_ChIP-Seq_ESCs_Human0.69119839
120FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.67711700

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.36973707
2MP0010094_abnormal_chromosome_stability4.51962829
3MP0003111_abnormal_nucleus_morphology4.33055274
4MP0008057_abnormal_DNA_replication4.17880991
5MP0003077_abnormal_cell_cycle4.05223872
6MP0004957_abnormal_blastocyst_morpholog4.04514785
7MP0008058_abnormal_DNA_repair3.66977038
8MP0008007_abnormal_cellular_replicative3.12435856
9MP0008932_abnormal_embryonic_tissue2.70725088
10MP0008877_abnormal_DNA_methylation2.57563226
11MP0003123_paternal_imprinting2.43407705
12MP0003786_premature_aging2.16256783
13MP0000350_abnormal_cell_proliferation2.07859549
14MP0001730_embryonic_growth_arrest1.96037291
15MP0006292_abnormal_olfactory_placode1.90938585
16MP0003718_maternal_effect1.90351474
17MP0010307_abnormal_tumor_latency1.89414664
18MP0003121_genomic_imprinting1.67019415
19MP0004147_increased_porphyrin_level1.62277368
20MP0002132_abnormal_respiratory_system1.55874882
21MP0006072_abnormal_retinal_apoptosis1.54307350
22MP0002396_abnormal_hematopoietic_system1.53026085
23MP0001672_abnormal_embryogenesis/_devel1.52506912
24MP0005380_embryogenesis_phenotype1.52506912
25MP0006035_abnormal_mitochondrial_morpho1.47211780
26MP0009333_abnormal_splenocyte_physiolog1.43121829
27MP0001697_abnormal_embryo_size1.42900408
28MP0010030_abnormal_orbit_morphology1.39671966
29MP0003315_abnormal_perineum_morphology1.39162128
30MP0003136_yellow_coat_color1.36448998
31MP0002210_abnormal_sex_determination1.33716374
32MP0002102_abnormal_ear_morphology1.32843941
33MP0002163_abnormal_gland_morphology1.32817581
34MP0002085_abnormal_embryonic_tissue1.30426034
35MP0000313_abnormal_cell_death1.30325118
36MP0000372_irregular_coat_pigmentation1.29828952
37MP0003567_abnormal_fetal_cardiomyocyte1.29092441
38MP0003984_embryonic_growth_retardation1.29031802
39MP0002080_prenatal_lethality1.28922011
40MP0010352_gastrointestinal_tract_polyps1.28364166
41MP0005499_abnormal_olfactory_system1.27749362
42MP0005394_taste/olfaction_phenotype1.27749362
43MP0002736_abnormal_nociception_after1.26299608
44MP0003890_abnormal_embryonic-extraembry1.25849085
45MP0006036_abnormal_mitochondrial_physio1.25597817
46MP0005075_abnormal_melanosome_morpholog1.24776499
47MP0002088_abnormal_embryonic_growth/wei1.24686309
48MP0002938_white_spotting1.23795829
49MP0005253_abnormal_eye_physiology1.22342343
50MP0000490_abnormal_crypts_of1.21706009
51MP0001968_abnormal_touch/_nociception1.20783605
52MP0001835_abnormal_antigen_presentation1.20303280
53MP0002019_abnormal_tumor_incidence1.19211635
54MP0001293_anophthalmia1.18494288
55MP0002277_abnormal_respiratory_mucosa1.16854579
56MP0003941_abnormal_skin_development1.15158639
57MP0002084_abnormal_developmental_patter1.14479352
58MP0003763_abnormal_thymus_physiology1.12069975
59MP0005084_abnormal_gallbladder_morpholo1.11196829
60MP0004808_abnormal_hematopoietic_stem1.10701705
61MP0001145_abnormal_male_reproductive1.10054360
62MP0005645_abnormal_hypothalamus_physiol1.09524920
63MP0001929_abnormal_gametogenesis1.07632253
64MP0003221_abnormal_cardiomyocyte_apopto1.07517188
65MP0002086_abnormal_extraembryonic_tissu1.06238830
66MP0004197_abnormal_fetal_growth/weight/1.05951828
67MP0003787_abnormal_imprinting1.01745131
68MP0000569_abnormal_digit_pigmentation0.99927349
69MP0000653_abnormal_sex_gland0.99610104
70MP0001119_abnormal_female_reproductive0.98204846
71MP0002398_abnormal_bone_marrow0.97889624
72MP0003937_abnormal_limbs/digits/tail_de0.96344201
73MP0000015_abnormal_ear_pigmentation0.95176794
74MP0001764_abnormal_homeostasis0.93900949
75MP0000631_abnormal_neuroendocrine_gland0.93855509
76MP0002160_abnormal_reproductive_system0.92569731
77MP0000703_abnormal_thymus_morphology0.90108119
78MP0000566_synostosis0.89993288
79MP0005389_reproductive_system_phenotype0.86426234
80MP0003698_abnormal_male_reproductive0.85072771
81MP0005671_abnormal_response_to0.83639600
82MP0002233_abnormal_nose_morphology0.83023381
83MP0005551_abnormal_eye_electrophysiolog0.82967111
84MP0002751_abnormal_autonomic_nervous0.82305274
85MP0002722_abnormal_immune_system0.81896661
86MP0001485_abnormal_pinna_reflex0.81629558
87MP0003880_abnormal_central_pattern0.81271059
88MP0001529_abnormal_vocalization0.80858887
89MP0000537_abnormal_urethra_morphology0.79778818
90MP0002095_abnormal_skin_pigmentation0.79717660
91MP0000858_altered_metastatic_potential0.78393237
92MP0002148_abnormal_hypersensitivity_rea0.78251684
93MP0009785_altered_susceptibility_to0.77773779
94MP0000689_abnormal_spleen_morphology0.77175559
95MP0001286_abnormal_eye_development0.77042626
96MP0003186_abnormal_redox_activity0.76843780
97MP0005076_abnormal_cell_differentiation0.75608324
98MP0009697_abnormal_copulation0.75606418
99MP0002429_abnormal_blood_cell0.74308976
100MP0005391_vision/eye_phenotype0.72497093
101MP0003119_abnormal_digestive_system0.71795358
102MP0005646_abnormal_pituitary_gland0.71465977
103MP0000358_abnormal_cell_content/0.71350415
104MP0004742_abnormal_vestibular_system0.70793289
105MP0000716_abnormal_immune_system0.69832756
106MP0008995_early_reproductive_senescence0.68976686
107MP0002452_abnormal_antigen_presenting0.68823015
108MP0001984_abnormal_olfaction0.68496171
109MP0005174_abnormal_tail_pigmentation0.68035034
110MP0008872_abnormal_physiological_respon0.64702321
111MP0001819_abnormal_immune_cell0.64623957
112MP0003448_altered_tumor_morphology0.64572873
113MP0002638_abnormal_pupillary_reflex0.64518492
114MP0005384_cellular_phenotype0.64496151
115MP0002234_abnormal_pharynx_morphology0.64414879
116MP0002009_preneoplasia0.64273701
117MP0001800_abnormal_humoral_immune0.64050202
118MP0003806_abnormal_nucleotide_metabolis0.63120012
119MP0001919_abnormal_reproductive_system0.62831388
120MP0003943_abnormal_hepatobiliary_system0.62551661
121MP0002111_abnormal_tail_morphology0.62118215
122MP0001346_abnormal_lacrimal_gland0.62074664
123MP0005367_renal/urinary_system_phenotyp0.61914610
124MP0000516_abnormal_urinary_system0.61914610
125MP0002420_abnormal_adaptive_immunity0.61864419
126MP0001188_hyperpigmentation0.61783376
127MP0004133_heterotaxia0.61159191
128MP0005408_hypopigmentation0.60602581
129MP0000049_abnormal_middle_ear0.60319006
130MP0002653_abnormal_ependyma_morphology0.59754721
131MP0003938_abnormal_ear_development0.59700692
132MP0009703_decreased_birth_body0.59357353
133MP0008789_abnormal_olfactory_epithelium0.59109388
134MP0005397_hematopoietic_system_phenotyp0.58620084
135MP0001545_abnormal_hematopoietic_system0.58620084
136MP0005621_abnormal_cell_physiology0.58326542
137MP0000647_abnormal_sebaceous_gland0.57231890

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.18027340
2Chromosomal breakage induced by crosslinking agents (HP:0003221)4.45657630
3Chromsome breakage (HP:0040012)4.30976358
4Breast hypoplasia (HP:0003187)3.69064676
5Patellar aplasia (HP:0006443)3.66751268
6Reticulocytopenia (HP:0001896)3.51887212
7Meckel diverticulum (HP:0002245)3.48490044
8Aplasia/Hypoplasia of the patella (HP:0006498)3.40357923
9Abnormality of the preputium (HP:0100587)3.36444374
10Abnormality of the ileum (HP:0001549)3.27975136
11Abnormality of the labia minora (HP:0012880)3.24747864
12Abnormality of chromosome stability (HP:0003220)3.12971408
13Aplasia/Hypoplasia of the uvula (HP:0010293)3.12279506
14Volvulus (HP:0002580)3.08199442
15Oral leukoplakia (HP:0002745)3.04214816
16Medulloblastoma (HP:0002885)2.96762543
17Absent radius (HP:0003974)2.94624894
18Supernumerary spleens (HP:0009799)2.94321418
19Aplastic anemia (HP:0001915)2.86811646
20Cerebral hypomyelination (HP:0006808)2.86231322
21Rough bone trabeculation (HP:0100670)2.85588255
22Abnormality of the anterior horn cell (HP:0006802)2.80856065
23Degeneration of anterior horn cells (HP:0002398)2.80856065
24Small intestinal stenosis (HP:0012848)2.79794058
25Duodenal stenosis (HP:0100867)2.79794058
26Myelodysplasia (HP:0002863)2.76761086
27Absent forearm bone (HP:0003953)2.75285579
28Aplasia involving forearm bones (HP:0009822)2.75285579
29Colon cancer (HP:0003003)2.68710885
30Carpal bone hypoplasia (HP:0001498)2.66071027
31Abnormality of cells of the erythroid lineage (HP:0012130)2.65242999
32Abnormal lung lobation (HP:0002101)2.63212426
33Absent thumb (HP:0009777)2.62105392
34Acute encephalopathy (HP:0006846)2.61059149
35Agnosia (HP:0010524)2.59725868
36Acute necrotizing encephalopathy (HP:0006965)2.59493907
37Bone marrow hypocellularity (HP:0005528)2.59016146
38Increased CSF lactate (HP:0002490)2.56930403
39Premature graying of hair (HP:0002216)2.54686776
40Cleft eyelid (HP:0000625)2.52481203
41Duplicated collecting system (HP:0000081)2.49089746
42Abnormal number of erythroid precursors (HP:0012131)2.48659549
43Ectopic kidney (HP:0000086)2.43987618
44Increased hepatocellular lipid droplets (HP:0006565)2.42090671
45Horseshoe kidney (HP:0000085)2.40770688
46Severe combined immunodeficiency (HP:0004430)2.32998011
47Impulsivity (HP:0100710)2.32200819
48Increased serum lactate (HP:0002151)2.29882820
49Hypoplasia of the capital femoral epiphysis (HP:0003090)2.29074271
50Triphalangeal thumb (HP:0001199)2.27386323
51Abnormality of the duodenum (HP:0002246)2.26843213
52Abnormality of the renal collecting system (HP:0004742)2.26413008
53Cellular immunodeficiency (HP:0005374)2.24325644
54Mitochondrial inheritance (HP:0001427)2.23923503
55Progressive macrocephaly (HP:0004481)2.23639106
56Abnormal trabecular bone morphology (HP:0100671)2.23191311
57Selective tooth agenesis (HP:0001592)2.22805384
58Abnormal mitochondria in muscle tissue (HP:0008316)2.22449379
59Pallor (HP:0000980)2.21370636
60Methylmalonic acidemia (HP:0002912)2.21114265
61Tracheoesophageal fistula (HP:0002575)2.20897288
62Sloping forehead (HP:0000340)2.20503593
63Lipid accumulation in hepatocytes (HP:0006561)2.20399681
64Abnormal number of incisors (HP:0011064)2.20029859
65Pancreatic cysts (HP:0001737)2.18253399
66Combined immunodeficiency (HP:0005387)2.16502167
67Short thumb (HP:0009778)2.15738861
68Hyperglycinemia (HP:0002154)2.15023080
69Nephroblastoma (Wilms tumor) (HP:0002667)2.14371580
70Panhypogammaglobulinemia (HP:0003139)2.13290010
71Clubbing of toes (HP:0100760)2.10251705
7211 pairs of ribs (HP:0000878)2.10233390
73Abnormality of the pons (HP:0007361)2.10203767
74Macrocytic anemia (HP:0001972)2.08523949
75Neoplasm of the pancreas (HP:0002894)2.07633727
76Hypoplasia of the pons (HP:0012110)2.07200389
77Abnormality of DNA repair (HP:0003254)2.04647171
78Hepatocellular necrosis (HP:0001404)2.04247833
79Medial flaring of the eyebrow (HP:0010747)2.04003990
80Stenosis of the external auditory canal (HP:0000402)2.02369744
81Embryonal renal neoplasm (HP:0011794)2.02106434
82Aplasia/Hypoplasia of the sternum (HP:0006714)2.01307943
83Cortical dysplasia (HP:0002539)2.01276688
84Oligodactyly (hands) (HP:0001180)1.99601637
85Hypoglycemic seizures (HP:0002173)1.95810014
863-Methylglutaconic aciduria (HP:0003535)1.92495082
87Abnormal spermatogenesis (HP:0008669)1.92432195
88Abnormality of the carotid arteries (HP:0005344)1.91888976
89Congenital primary aphakia (HP:0007707)1.91400634
90Pulmonary fibrosis (HP:0002206)1.90924262
91Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.89557633
92Atresia of the external auditory canal (HP:0000413)1.88892198
93Microvesicular hepatic steatosis (HP:0001414)1.87984877
94Secondary amenorrhea (HP:0000869)1.87820629
95Hepatic necrosis (HP:0002605)1.85938428
96Poor head control (HP:0002421)1.85806034
97Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.85529079
98Absent epiphyses (HP:0010577)1.85529079
99Pancreatic fibrosis (HP:0100732)1.85394780
100Amaurosis fugax (HP:0100576)1.85255313
101Trismus (HP:0000211)1.85227329
102Optic nerve coloboma (HP:0000588)1.84960614
103Hyperalaninemia (HP:0003348)1.83826345
104Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.83826345
105Abnormality of alanine metabolism (HP:0010916)1.83826345
106Premature ovarian failure (HP:0008209)1.82533492
107Lymphoma (HP:0002665)1.81882981
108Lactic acidosis (HP:0003128)1.81761429
109Limb hypertonia (HP:0002509)1.81750304
110Nephrogenic diabetes insipidus (HP:0009806)1.81134029
111Molar tooth sign on MRI (HP:0002419)1.81088579
112Abnormality of midbrain morphology (HP:0002418)1.81088579
113Irregular epiphyses (HP:0010582)1.80160985
114Intestinal atresia (HP:0011100)1.79895196
115Glossoptosis (HP:0000162)1.79672658
116Aplasia/Hypoplasia of the sacrum (HP:0008517)1.79651483
117Cerebral edema (HP:0002181)1.78758284
118Gait imbalance (HP:0002141)1.78077045
119Rhabdomyosarcoma (HP:0002859)1.77702499
120Type 2 muscle fiber atrophy (HP:0003554)1.77656216
121Progressive inability to walk (HP:0002505)1.77550851
122Oligodactyly (HP:0012165)1.75873942
123Abnormality of the septum pellucidum (HP:0007375)1.75796984
124Abnormality of serum amino acid levels (HP:0003112)1.75140293
125Methylmalonic aciduria (HP:0012120)1.74286245
126Facial hemangioma (HP:0000329)1.74239119
127Small hand (HP:0200055)1.72763411
128Abnormality of cochlea (HP:0000375)1.72403185
129Facial cleft (HP:0002006)1.72283466
130Long clavicles (HP:0000890)1.72244040
131Microretrognathia (HP:0000308)1.71930232
132Muscle fiber atrophy (HP:0100295)1.71270380
133Pancytopenia (HP:0001876)1.71023444
134Neoplasm of the colon (HP:0100273)1.70145941
135Cutaneous melanoma (HP:0012056)1.69663683
136Ependymoma (HP:0002888)1.68976925
137Progressive microcephaly (HP:0000253)1.67563305
138Nephronophthisis (HP:0000090)1.66498953
139Glioma (HP:0009733)1.64467884
140Hypoplasia of the radius (HP:0002984)1.63646531
141Increased serum pyruvate (HP:0003542)1.62269342
142Abnormality of glycolysis (HP:0004366)1.62269342
143Hypoplastic pelvis (HP:0008839)1.61944981
144Septo-optic dysplasia (HP:0100842)1.61236404
145CNS hypomyelination (HP:0003429)1.60989255
146Abnormal protein glycosylation (HP:0012346)1.60045363
147Abnormal glycosylation (HP:0012345)1.60045363
148Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.60045363
149Abnormal protein N-linked glycosylation (HP:0012347)1.60045363
150True hermaphroditism (HP:0010459)1.59776708
151Aseptic necrosis (HP:0010885)1.59572640
152Basal cell carcinoma (HP:0002671)1.58551488
153Spinal muscular atrophy (HP:0007269)1.57996234
154Squamous cell carcinoma (HP:0002860)1.56837506
155IgG deficiency (HP:0004315)1.56618995

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.70194875
2CDC74.15004092
3WEE13.70713298
4SRPK13.59321077
5EIF2AK13.39137185
6PLK42.90115029
7ACVR1B2.56087843
8MAP4K22.48916923
9BRSK22.45029318
10NEK22.40073564
11TAOK32.31892688
12TTK2.30957712
13TRIM282.29054899
14MKNK12.16540836
15VRK12.13472177
16STK162.11598616
17PLK12.08957174
18TSSK62.08533749
19PLK32.05865738
20EIF2AK31.94113314
21PBK1.93275214
22TNIK1.85170155
23RPS6KA41.74456184
24DYRK31.73635212
25AURKB1.71361999
26VRK21.67969733
27MKNK21.65209252
28WNK31.59025768
29ATR1.57526475
30CCNB11.54489984
31PASK1.53089984
32CHEK21.50577484
33NME21.49610725
34TESK21.47774324
35ZAK1.46914412
36CDK71.41549407
37PDK21.41143574
38BRSK11.36413306
39NEK11.34418008
40TLK11.33518057
41STK38L1.25887648
42CDK81.21894913
43EIF2AK21.19615251
44CHEK11.19335458
45AURKA1.19000620
46PNCK1.10902182
47DYRK21.05185031
48RPS6KB21.04196157
49STK41.03266026
50BRAF1.02474450
51TGFBR11.00410852
52BRD40.96501147
53FRK0.94321720
54ATM0.92992268
55MAP3K80.89167168
56BCR0.89103153
57STK390.88443169
58MELK0.87456722
59STK30.86848592
60MST40.86639473
61WNK40.83224013
62MAP3K40.82726983
63TAF10.82529926
64RPS6KA50.80178339
65PIM20.80064394
66PIM10.78974236
67AKT30.74559955
68CSNK2A10.74139392
69CDK20.74049410
70EPHA20.73483751
71BCKDK0.72992920
72CDK30.70045631
73CDK120.68722715
74STK100.68537542
75CDK40.67966765
76BMPR1B0.65980352
77CDK10.65687937
78MAPK130.65306373
79CSNK2A20.65191644
80PLK20.64784841
81CSNK1G10.63969817
82CDK190.63162482
83INSRR0.62982539
84IRAK40.62058480
85OXSR10.60842885
86ADRBK20.59932500
87ERBB30.58512891
88PAK40.57147910
89CLK10.56650753
90CSNK1G30.56359488
91RAF10.55541004
92TESK10.53595879
93MARK30.53122070
94PAK10.52353462
95TXK0.51364718
96CSNK1E0.50942619
97IKBKB0.50867433
98CHUK0.50831489
99NLK0.49077168
100CSNK1G20.48660533
101MAP3K140.48023250
102MAP2K70.47886034
103NUAK10.44789618
104YES10.44617902
105CSNK1A1L0.43612408
106PRKCI0.40164455
107CASK0.39825560
108BLK0.38922762
109STK240.38868088
110NEK90.36398036
111LIMK10.36360564
112NME10.35608961
113TAOK20.34532682
114TEC0.34128468
115GRK10.34034524
116JAK30.33047600
117IRAK30.32334029
118KSR10.31478111
119ALK0.29038791
120PRKCG0.28527315
121DYRK1A0.28116565
122IRAK10.27599995
123CDK90.25687905
124NEK60.25429919
125CDK60.24723525
126RPS6KB10.24225857
127BMPR20.24221026
128LATS20.24218774
129PRKDC0.22978859
130FGFR10.22763397
131KDR0.22625161
132SIK30.21525133
133AKT20.20215893
134AKT10.20175073
135MAP3K50.20093326
136LYN0.19666894

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.24685699
2Mismatch repair_Homo sapiens_hsa034304.01915565
3RNA polymerase_Homo sapiens_hsa030203.70191826
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.67262358
5Proteasome_Homo sapiens_hsa030503.66626168
6* Spliceosome_Homo sapiens_hsa030403.25832435
7RNA transport_Homo sapiens_hsa030133.02856535
8Homologous recombination_Homo sapiens_hsa034403.01776457
9Ribosome_Homo sapiens_hsa030102.97671469
10Nucleotide excision repair_Homo sapiens_hsa034202.87709830
11Base excision repair_Homo sapiens_hsa034102.83971384
12Cell cycle_Homo sapiens_hsa041102.68718940
13Basal transcription factors_Homo sapiens_hsa030222.58710340
14Pyrimidine metabolism_Homo sapiens_hsa002402.41496567
15Fanconi anemia pathway_Homo sapiens_hsa034602.36359040
16RNA degradation_Homo sapiens_hsa030182.05882637
17One carbon pool by folate_Homo sapiens_hsa006702.01259140
18Non-homologous end-joining_Homo sapiens_hsa034501.98450702
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.91326762
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.87672933
21mRNA surveillance pathway_Homo sapiens_hsa030151.81236483
22Propanoate metabolism_Homo sapiens_hsa006401.56365650
23Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.52396037
24p53 signaling pathway_Homo sapiens_hsa041151.50634755
25Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.46883100
26Purine metabolism_Homo sapiens_hsa002301.35669665
27Epstein-Barr virus infection_Homo sapiens_hsa051691.32258691
28Protein export_Homo sapiens_hsa030601.18922587
29Herpes simplex infection_Homo sapiens_hsa051681.18084214
30Systemic lupus erythematosus_Homo sapiens_hsa053221.14278467
31Steroid biosynthesis_Homo sapiens_hsa001001.09947151
32Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.07803801
33Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.04205724
34Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.03053654
35Allograft rejection_Homo sapiens_hsa053301.00446567
36Fatty acid elongation_Homo sapiens_hsa000620.98381127
37Vitamin B6 metabolism_Homo sapiens_hsa007500.98374827
38Antigen processing and presentation_Homo sapiens_hsa046120.97578900
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.97228598
40Oocyte meiosis_Homo sapiens_hsa041140.94623536
41Pyruvate metabolism_Homo sapiens_hsa006200.90915918
42Legionellosis_Homo sapiens_hsa051340.90682817
43Huntingtons disease_Homo sapiens_hsa050160.90520866
44Butanoate metabolism_Homo sapiens_hsa006500.85958102
45Viral carcinogenesis_Homo sapiens_hsa052030.85352702
46Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.84959960
47Graft-versus-host disease_Homo sapiens_hsa053320.84136532
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.77130909
49Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.77015031
50Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.73427014
51Primary immunodeficiency_Homo sapiens_hsa053400.73119197
52Intestinal immune network for IgA production_Homo sapiens_hsa046720.72334676
53NF-kappa B signaling pathway_Homo sapiens_hsa040640.71367908
54HTLV-I infection_Homo sapiens_hsa051660.70315117
55Carbon metabolism_Homo sapiens_hsa012000.67271414
56Influenza A_Homo sapiens_hsa051640.66533126
57Sulfur relay system_Homo sapiens_hsa041220.66427881
58Measles_Homo sapiens_hsa051620.65857511
59Autoimmune thyroid disease_Homo sapiens_hsa053200.65747155
60Parkinsons disease_Homo sapiens_hsa050120.63896076
61Oxidative phosphorylation_Homo sapiens_hsa001900.60030529
62Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.59179616
63NOD-like receptor signaling pathway_Homo sapiens_hsa046210.58129177
64Asthma_Homo sapiens_hsa053100.57949701
65Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.57253400
66Type I diabetes mellitus_Homo sapiens_hsa049400.57004671
67MicroRNAs in cancer_Homo sapiens_hsa052060.56038955
68Phototransduction_Homo sapiens_hsa047440.47022783
69Transcriptional misregulation in cancer_Homo sapiens_hsa052020.46667278
70Nicotine addiction_Homo sapiens_hsa050330.46320682
71Apoptosis_Homo sapiens_hsa042100.46192625
72Drug metabolism - other enzymes_Homo sapiens_hsa009830.45021802
73RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.44274794
74TGF-beta signaling pathway_Homo sapiens_hsa043500.43375512
75Regulation of autophagy_Homo sapiens_hsa041400.43235976
76Hepatitis B_Homo sapiens_hsa051610.43138429
77Pentose phosphate pathway_Homo sapiens_hsa000300.40101026
78Arachidonic acid metabolism_Homo sapiens_hsa005900.39625540
79Nitrogen metabolism_Homo sapiens_hsa009100.39495365
80Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.38962757
81Small cell lung cancer_Homo sapiens_hsa052220.38628721
82Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.38261762
832-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.37934267
84Cysteine and methionine metabolism_Homo sapiens_hsa002700.37770556
85Thyroid cancer_Homo sapiens_hsa052160.37655398
86Peroxisome_Homo sapiens_hsa041460.37453357
87Alcoholism_Homo sapiens_hsa050340.36186664
88Viral myocarditis_Homo sapiens_hsa054160.35473072
89Hippo signaling pathway_Homo sapiens_hsa043900.34546362
90Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.34409330
91Glutathione metabolism_Homo sapiens_hsa004800.34133172
92Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.33816575
93Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.33471397
94Hematopoietic cell lineage_Homo sapiens_hsa046400.32779002
95Basal cell carcinoma_Homo sapiens_hsa052170.31722594
96Shigellosis_Homo sapiens_hsa051310.30811740
97Lysine degradation_Homo sapiens_hsa003100.30277995
98Colorectal cancer_Homo sapiens_hsa052100.29778564
99Circadian rhythm_Homo sapiens_hsa047100.26981578
100Taste transduction_Homo sapiens_hsa047420.26478697
101Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.26456350
102Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.26332127
103Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.24753292
104Fatty acid metabolism_Homo sapiens_hsa012120.24463888
105Biosynthesis of amino acids_Homo sapiens_hsa012300.24003529
106Leishmaniasis_Homo sapiens_hsa051400.23710783
107Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.22509816
108Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.22435750
109Olfactory transduction_Homo sapiens_hsa047400.22403187
110Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.21629676
111Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.21045804
112Caffeine metabolism_Homo sapiens_hsa002320.20760616
113Pathways in cancer_Homo sapiens_hsa052000.18998923
114Folate biosynthesis_Homo sapiens_hsa007900.18529472
115Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.18378562
116HIF-1 signaling pathway_Homo sapiens_hsa040660.17756410
117Notch signaling pathway_Homo sapiens_hsa043300.17647625
118SNARE interactions in vesicular transport_Homo sapiens_hsa041300.17606365
119Ether lipid metabolism_Homo sapiens_hsa005650.17595470
120alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.17567703
121Rheumatoid arthritis_Homo sapiens_hsa053230.17536724
122Cardiac muscle contraction_Homo sapiens_hsa042600.16528640
123Alzheimers disease_Homo sapiens_hsa050100.16445842
124Linoleic acid metabolism_Homo sapiens_hsa005910.16387466
125Selenocompound metabolism_Homo sapiens_hsa004500.16304697
126Toll-like receptor signaling pathway_Homo sapiens_hsa046200.16081380
127Prostate cancer_Homo sapiens_hsa052150.15161264
128Pertussis_Homo sapiens_hsa051330.14537258
129Jak-STAT signaling pathway_Homo sapiens_hsa046300.14000095
130Malaria_Homo sapiens_hsa051440.13326422
131TNF signaling pathway_Homo sapiens_hsa046680.13204456
132Metabolic pathways_Homo sapiens_hsa011000.11963311
133Hedgehog signaling pathway_Homo sapiens_hsa043400.11574337
134Sulfur metabolism_Homo sapiens_hsa009200.10683947
135Wnt signaling pathway_Homo sapiens_hsa043100.04878212
136N-Glycan biosynthesis_Homo sapiens_hsa005100.01066249
137Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.00947715
138Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.00146497
139Maturity onset diabetes of the young_Homo sapiens_hsa04950-0.0022124

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