POM121L12

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cell-cell recognition (GO:0009988)9.95740353
2spermatid development (GO:0007286)9.75247926
3motile cilium assembly (GO:0044458)9.66682107
4piRNA metabolic process (GO:0034587)9.57446690
5plasma membrane fusion (GO:0045026)9.51593005
6reproduction (GO:0000003)8.86447778
7regulation of cilium movement (GO:0003352)8.75232090
8cilium movement (GO:0003341)8.57691066
9epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.18476678
10male meiosis (GO:0007140)8.05122042
11synaptonemal complex organization (GO:0070193)7.83092789
12synaptonemal complex assembly (GO:0007130)7.56858408
13single fertilization (GO:0007338)7.25493329
14sperm capacitation (GO:0048240)7.25450531
15negative regulation of inclusion body assembly (GO:0090084)6.86560133
16spermatogenesis (GO:0007283)6.45967118
17male gamete generation (GO:0048232)6.43580757
18fertilization (GO:0009566)6.29357362
19organic cation transport (GO:0015695)5.94306766
20microtubule depolymerization (GO:0007019)5.91837604
21gamete generation (GO:0007276)5.91325460
22DNA methylation involved in gamete generation (GO:0043046)5.85045217
23male meiosis I (GO:0007141)5.70000276
24regulation of inclusion body assembly (GO:0090083)5.62759000
25germ cell development (GO:0007281)5.57231103
26cellular process involved in reproduction in multicellular organism (GO:0022412)5.40900032
27ventricular system development (GO:0021591)5.38434976
28chromosome organization involved in meiosis (GO:0070192)5.25754992
29regulation of microtubule-based movement (GO:0060632)5.18199605
30calcium ion-dependent exocytosis (GO:0017156)5.16856449
31seminiferous tubule development (GO:0072520)4.99054376
32meiotic nuclear division (GO:0007126)4.85166808
33cell recognition (GO:0008037)4.78544726
34left/right pattern formation (GO:0060972)4.71141170
35microtubule severing (GO:0051013)4.70487525
36multicellular organismal reproductive process (GO:0048609)4.65290138
37meiosis I (GO:0007127)4.57705500
38meiotic cell cycle (GO:0051321)4.39490670
39chromosome condensation (GO:0030261)4.33890720
40spermatid nucleus differentiation (GO:0007289)4.31604435
41DNA packaging (GO:0006323)4.23653473
42glycerol ether metabolic process (GO:0006662)4.08645595
43chaperone-mediated protein complex assembly (GO:0051131)3.88548274
44protein localization to cilium (GO:0061512)3.88388190
45genitalia morphogenesis (GO:0035112)3.87532790
46protein polyglutamylation (GO:0018095)3.85411145
47ether metabolic process (GO:0018904)3.77333678
48multicellular organismal development (GO:0007275)3.74348786
49gene silencing by RNA (GO:0031047)3.63507292
50monoubiquitinated protein deubiquitination (GO:0035520)3.61434998
51single strand break repair (GO:0000012)3.37359008
52sexual reproduction (GO:0019953)3.37336107
53regulation of spindle checkpoint (GO:0090231)3.35836034
54amino-acid betaine transport (GO:0015838)3.31633472
55carnitine transport (GO:0015879)3.31633472
56protein refolding (GO:0042026)3.30338954
57intraciliary transport (GO:0042073)3.27554806
58carnitine transmembrane transport (GO:1902603)3.23707384
59axoneme assembly (GO:0035082)3.20937872
60microtubule-based movement (GO:0007018)3.20157888
61meiotic cell cycle process (GO:1903046)3.18337460
62negative regulation of organelle assembly (GO:1902116)3.16874206
63nucleus organization (GO:0006997)3.06588658
64synapsis (GO:0007129)3.05726221
65mitotic sister chromatid cohesion (GO:0007064)3.05059728
66microtubule polymerization or depolymerization (GO:0031109)3.01580079
67cilium organization (GO:0044782)3.00862383
68alditol metabolic process (GO:0019400)2.97976851
69polyol catabolic process (GO:0046174)2.96377664
70interferon-gamma secretion (GO:0072643)2.95373482
71glycolytic process (GO:0006096)2.91347587
72nucleoside diphosphate phosphorylation (GO:0006165)2.91034394
73gene silencing (GO:0016458)2.87670087
74protein K11-linked deubiquitination (GO:0035871)2.87168340
75cilium assembly (GO:0042384)2.85929142
76peptidyl-glutamic acid modification (GO:0018200)2.81867073
77regulation of meiosis I (GO:0060631)2.80463392
78RNA localization (GO:0006403)2.77185763
79lactate metabolic process (GO:0006089)2.76412415
80cellular component assembly involved in morphogenesis (GO:0010927)2.75154870
81regulation of centriole replication (GO:0046599)2.74704788
82cilium morphogenesis (GO:0060271)2.73936094
83nuclear pore complex assembly (GO:0051292)2.72550662
84sequestering of actin monomers (GO:0042989)2.63023936
85centriole assembly (GO:0098534)2.57109706
86sex differentiation (GO:0007548)2.56600183
87glycerol metabolic process (GO:0006071)2.55419580
88regulation of cilium assembly (GO:1902017)2.52577306
89sperm motility (GO:0030317)13.4286480
90cilium or flagellum-dependent cell motility (GO:0001539)12.8383114
91fusion of sperm to egg plasma membrane (GO:0007342)12.4975085
92acrosome reaction (GO:0007340)11.6356159
93sperm-egg recognition (GO:0035036)11.1328732
94axonemal dynein complex assembly (GO:0070286)10.7702473
95acrosome assembly (GO:0001675)10.5336190
96multicellular organism reproduction (GO:0032504)10.4333682
97cell wall macromolecule metabolic process (GO:0044036)10.4320311
98cell wall macromolecule catabolic process (GO:0016998)10.4320311
99binding of sperm to zona pellucida (GO:0007339)10.2911594
100epithelial cilium movement (GO:0003351)10.1704065

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.18382251
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.08845085
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.96142223
4STAT6_21828071_ChIP-Seq_BEAS2B_Human2.63664942
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.62656545
6PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.59529005
7CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.37712834
8GATA1_26923725_Chip-Seq_HPCs_Mouse2.30810178
9VDR_22108803_ChIP-Seq_LS180_Human2.29890612
10CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.18332241
11EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.02551990
12MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse11.0882526
13ZNF274_21170338_ChIP-Seq_K562_Hela1.93591006
14ELK4_26923725_Chip-Seq_MESODERM_Mouse1.90084434
15FLI1_27457419_Chip-Seq_LIVER_Mouse1.89923231
16ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.80971091
17FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.66031281
18PCGF2_27294783_Chip-Seq_ESCs_Mouse1.62743539
19KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.58995935
20* STAT1_17558387_ChIP-Seq_HELA_Human1.58066502
21WDR5_24793694_ChIP-Seq_LNCAP_Human1.56494417
22* TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.52986056
23SOX2_22085726_ChIP-Seq_NPCs_Mouse1.49823732
24RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.41097224
25* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.40238356
26GATA3_21867929_ChIP-Seq_CD8_Mouse1.39304383
27GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38823756
28* GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.38515101
29KAP1_22055183_ChIP-Seq_ESCs_Mouse1.35279978
30FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.32766586
31TAL1_26923725_Chip-Seq_HPCs_Mouse1.32356535
32REST_21632747_ChIP-Seq_MESCs_Mouse1.31754187
33MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.30703109
34SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.27850550
35* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.27456817
36* CBP_20019798_ChIP-Seq_JUKART_Human1.27456817
37* KDM2B_26808549_Chip-Seq_REH_Human1.24923889
38NFE2_27457419_Chip-Seq_LIVER_Mouse1.24500364
39P53_21459846_ChIP-Seq_SAOS-2_Human1.24443170
40PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.22283130
41RAD21_21589869_ChIP-Seq_MESCs_Mouse1.20405459
42PCGF2_27294783_Chip-Seq_NPCs_Mouse1.18546794
43SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.17945127
44TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17826333
45POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.17826333
46* LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.17084338
47GATA3_21867929_ChIP-Seq_TH1_Mouse1.15959810
48PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.15871015
49GF1_26923725_Chip-Seq_HPCs_Mouse1.13247848
50SUZ12_27294783_Chip-Seq_NPCs_Mouse1.09205795
51CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.08866955
52RUNX1_26923725_Chip-Seq_HPCs_Mouse1.08763128
53TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.08308862
54TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07353489
55SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.07083219
56* FLI1_21867929_ChIP-Seq_TH2_Mouse1.05520729
57YY1_22570637_ChIP-Seq_MALME-3M_Human1.03670964
58RXRA_24833708_ChIP-Seq_LIVER_Mouse1.03446128
59SPI1_26923725_Chip-Seq_HPCs_Mouse1.02323372
60* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.01884533
61MYC_27129775_Chip-Seq_CORNEA_Mouse1.01658439
62CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01656669
63EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.01420246
64ERG_20517297_ChIP-Seq_VCAP_Human1.00931336
65CBX2_27304074_Chip-Seq_ESCs_Mouse1.00464970
66PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.00148617
67PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.00077295
68CRX_20693478_ChIP-Seq_RETINA_Mouse0.99275452
69RARA_24833708_ChIP-Seq_LIVER_Mouse0.98443298
70ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.97714874
71RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.95350865
72NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.95239659
73ESET_19884257_ChIP-Seq_ESCs_Mouse0.94897507
74EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.94179609
75CTCF_20526341_ChIP-Seq_ESCs_Human0.93307683
76TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.91985806
77SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.91973139
78CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.91833657
79PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.91425208
80SOX2_21211035_ChIP-Seq_LN229_Human0.91255136
81NANOG_18555785_Chip-Seq_ESCs_Mouse0.90258646
82ELF1_20517297_ChIP-Seq_JURKAT_Human0.89634565
83SOX11_22085726_ChIP-Seq_ESNs_Mouse0.89095171
84NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.88594796
85RBPJ_22232070_ChIP-Seq_NCS_Mouse0.88579538
86OCT4_18555785_Chip-Seq_ESCs_Mouse0.88399211
87CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.88002673
88GATA1_19941827_ChIP-Seq_MEL86_Mouse0.87819767
89NFYB_21822215_ChIP-Seq_K562_Human0.87323420
90NANOG_20526341_ChIP-Seq_ESCs_Human0.87219750
91TET1_21451524_ChIP-Seq_MESCs_Mouse0.87109767
92FLI1_21867929_ChIP-Seq_CD8_Mouse0.86725086
93OCT4_21477851_ChIP-Seq_ESCs_Mouse0.86134198
94LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.85607932
95MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.85158301
96RNF2_27304074_Chip-Seq_NSC_Mouse0.84314182
97P53_22387025_ChIP-Seq_ESCs_Mouse0.83161342
98* CTBP2_25329375_ChIP-Seq_LNCAP_Human0.83065978
99JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.82812819
100PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.82617002

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive6.07186144
2MP0001929_abnormal_gametogenesis5.54902898
3MP0008877_abnormal_DNA_methylation4.61811893
4MP0002210_abnormal_sex_determination3.64864020
5MP0002161_abnormal_fertility/fecundity3.32408874
6MP0001145_abnormal_male_reproductive3.06440401
7MP0002653_abnormal_ependyma_morphology3.06162043
8MP0000653_abnormal_sex_gland2.65377431
9MP0005670_abnormal_white_adipose2.25103497
10MP0005410_abnormal_fertilization15.9906962
11MP0005623_abnormal_meninges_morphology1.89932019
12MP0002160_abnormal_reproductive_system1.80182873
13MP0003646_muscle_fatigue1.65354301
14MP0002282_abnormal_trachea_morphology1.43273432
15MP0004233_abnormal_muscle_weight1.22076956
16MP0008995_early_reproductive_senescence1.07702176
17MP0008058_abnormal_DNA_repair1.01878872
18MP0001765_abnormal_ion_homeostasis0.98406025
19MP0001984_abnormal_olfaction0.96950359
20MP0000569_abnormal_digit_pigmentation0.96300960
21MP0005647_abnormal_sex_gland0.95335123
22MP0009046_muscle_twitch0.91612726
23MP0005389_reproductive_system_phenotype0.85768142
24MP0003329_amyloid_beta_deposits0.80846972
25MP0003115_abnormal_respiratory_system0.79326211
26MP0010094_abnormal_chromosome_stability0.78564811
27MP0003011_delayed_dark_adaptation0.77478373
28MP0003878_abnormal_ear_physiology0.72775760
29MP0005377_hearing/vestibular/ear_phenot0.72775760
30MP0000358_abnormal_cell_content/0.66824003
31MP0002234_abnormal_pharynx_morphology0.60706167
32MP0003111_abnormal_nucleus_morphology0.57472419
33MP0008057_abnormal_DNA_replication0.57129143
34MP0005636_abnormal_mineral_homeostasis0.55121366
35MP0009278_abnormal_bone_marrow0.54351048
36MP0008007_abnormal_cellular_replicative0.52587085
37MP0003786_premature_aging0.51048867
38MP0005397_hematopoietic_system_phenotyp0.50269557
39MP0001545_abnormal_hematopoietic_system0.50269557
40MP0003699_abnormal_female_reproductive0.49924068
41MP0001293_anophthalmia0.49227203
42MP0005666_abnormal_adipose_tissue0.44832060
43MP0001324_abnormal_eye_pigmentation0.43944226
44MP0004808_abnormal_hematopoietic_stem0.42426729
45MP0004036_abnormal_muscle_relaxation0.42169866
46MP0000604_amyloidosis0.41721477
47MP0003950_abnormal_plasma_membrane0.41268828
48MP0002928_abnormal_bile_duct0.39019948
49MP0002269_muscular_atrophy0.38010730
50MP0001764_abnormal_homeostasis0.37913538
51MP0001730_embryonic_growth_arrest0.37663528
52MP0001119_abnormal_female_reproductive0.37204044
53MP0005253_abnormal_eye_physiology0.33031229
54MP0005391_vision/eye_phenotype0.32853274
55MP0000534_abnormal_ureter_morphology0.31860435
56MP0005551_abnormal_eye_electrophysiolog0.31834036
57MP0003942_abnormal_urinary_system0.31355916
58MP0002971_abnormal_brown_adipose0.30739954
59MP0004811_abnormal_neuron_physiology0.30729624
60MP0009115_abnormal_fat_cell0.29285168
61MP0003861_abnormal_nervous_system0.29283842
62MP0001727_abnormal_embryo_implantation0.28849353
63MP0000313_abnormal_cell_death0.27841494
64MP0006036_abnormal_mitochondrial_physio0.27408988
65MP0002152_abnormal_brain_morphology0.27319638
66MP0002736_abnormal_nociception_after0.26305663
67MP0000015_abnormal_ear_pigmentation0.26280612
68MP0008961_abnormal_basal_metabolism0.26070624
69MP0010307_abnormal_tumor_latency0.25213326
70MP0004133_heterotaxia0.25045869
71MP0002092_abnormal_eye_morphology0.24959366
72MP0006035_abnormal_mitochondrial_morpho0.24244761
73MP0003879_abnormal_hair_cell0.24078190
74MP0004019_abnormal_vitamin_homeostasis0.22322541
75MP0003631_nervous_system_phenotype0.21555021
76MP0002084_abnormal_developmental_patter0.20403140
77MP0003948_abnormal_gas_homeostasis0.20388363
78MP0003077_abnormal_cell_cycle0.19934041
79MP0002102_abnormal_ear_morphology0.19473139
80MP0003045_fibrosis0.19458330
81MP0005423_abnormal_somatic_nervous0.19252910
82MP0002169_no_abnormal_phenotype0.18951727
83MP0002873_normal_phenotype0.18693130
84MP0001661_extended_life_span0.18484332
85MP0001672_abnormal_embryogenesis/_devel0.17848663
86MP0005380_embryogenesis_phenotype0.17848663
87MP0001986_abnormal_taste_sensitivity0.17737737
88MP0002295_abnormal_pulmonary_circulatio0.17692109
89MP0003936_abnormal_reproductive_system0.17076024
90MP0009672_abnormal_birth_weight0.16819571
91MP0003632_abnormal_nervous_system0.16269405
92MP0005174_abnormal_tail_pigmentation0.15987347
93MP0003633_abnormal_nervous_system0.15963937
94MP0000751_myopathy0.15941551
95MP0001697_abnormal_embryo_size0.15861586
96MP0002405_respiratory_system_inflammati0.14889602
97MP0002229_neurodegeneration0.14617832
98MP0004043_abnormal_pH_regulation0.14588761
99MP0000001_mammalian_phenotype0.14238943
100MP0004742_abnormal_vestibular_system0.13439861

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory epithelium morphology (HP:0012253)9.21455162
2Abnormal respiratory motile cilium morphology (HP:0005938)9.21455162
3Abnormal respiratory motile cilium physiology (HP:0012261)9.19626827
4Rhinitis (HP:0012384)7.79041595
5Abnormal ciliary motility (HP:0012262)7.20846076
6Chronic bronchitis (HP:0004469)7.09740898
7Infertility (HP:0000789)6.87009918
8Nasal polyposis (HP:0100582)6.50723391
9Abnormality of the nasal mucosa (HP:0000433)5.40911618
10Bronchitis (HP:0012387)4.63595921
11Bronchiectasis (HP:0002110)4.61399493
12Nephronophthisis (HP:0000090)4.52196165
13Male infertility (HP:0003251)4.11490743
14Abnormality of the renal medulla (HP:0100957)3.43581776
15Abnormal spermatogenesis (HP:0008669)3.39817274
16Recurrent otitis media (HP:0000403)3.39565635
17Recurrent sinusitis (HP:0011108)3.25976347
18Gonadotropin excess (HP:0000837)3.13028543
19Recurrent bronchitis (HP:0002837)2.99499270
20Impulsivity (HP:0100710)2.98182271
21Tubulointerstitial nephritis (HP:0001970)2.94758516
22Tubular atrophy (HP:0000092)2.66840100
23Abnormality of the lower motor neuron (HP:0002366)2.54276417
24Abnormality of midbrain morphology (HP:0002418)2.50789535
25Molar tooth sign on MRI (HP:0002419)2.50789535
26Tubulointerstitial abnormality (HP:0001969)2.44324665
27Azoospermia (HP:0000027)2.26003015
28Medial flaring of the eyebrow (HP:0010747)2.24981102
29Cholecystitis (HP:0001082)2.18257184
30Abnormal gallbladder physiology (HP:0012438)2.18257184
31Hypoplasia of the capital femoral epiphysis (HP:0003090)2.14961100
32Spastic tetraparesis (HP:0001285)2.12967317
33Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.2236220
34Dynein arm defect of respiratory motile cilia (HP:0012255)13.0515383
35Absent/shortened dynein arms (HP:0200106)13.0515383
36Postaxial foot polydactyly (HP:0001830)1.99973738
37Stage 5 chronic kidney disease (HP:0003774)1.94405675
38Tubulointerstitial fibrosis (HP:0005576)1.91239102
39Amyotrophic lateral sclerosis (HP:0007354)1.89060289
40Heterotopia (HP:0002282)1.87852189
41Fibular hypoplasia (HP:0003038)1.83616708
42Absent frontal sinuses (HP:0002688)1.77784333
43Congenital hepatic fibrosis (HP:0002612)1.76777030
44Abnormal drinking behavior (HP:0030082)1.75717237
45Polydipsia (HP:0001959)1.75717237
46Dyschromatopsia (HP:0007641)1.74455443
47Short ribs (HP:0000773)1.73972603
48Abnormality of the renal cortex (HP:0011035)1.73038458
49Bell-shaped thorax (HP:0001591)1.71876197
50Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.69913893
51Absent epiphyses (HP:0010577)1.69913893
52Impaired proprioception (HP:0010831)1.66573131
53Renal dysplasia (HP:0000110)1.66477945
54Oculomotor apraxia (HP:0000657)1.62531771
55Choroideremia (HP:0001139)1.61320736
56Bile duct proliferation (HP:0001408)1.59762706
57Abnormal biliary tract physiology (HP:0012439)1.59762706
58Abnormality of renal excretion (HP:0011036)1.59060333
59Abnormality of dentin (HP:0010299)1.58594647
60Abnormality of permanent molar morphology (HP:0011071)1.57201069
61Abnormality of the dental root (HP:0006486)1.57201069
62Taurodontia (HP:0000679)1.57201069
63Decreased central vision (HP:0007663)1.56959786
64J-shaped sella turcica (HP:0002680)1.56089026
65Chronic sinusitis (HP:0011109)1.54322545
66Deformed sella turcica (HP:0002681)1.50931677
67Microglossia (HP:0000171)1.50191356
68Broad distal phalanx of finger (HP:0009836)1.46729589
69Abnormality of molar morphology (HP:0011070)1.46345760
70Abnormality of molar (HP:0011077)1.46345760
71Postaxial hand polydactyly (HP:0001162)1.46143781
72Abnormality of the anterior horn cell (HP:0006802)1.45451735
73Degeneration of anterior horn cells (HP:0002398)1.45451735
74Abnormality of the dental pulp (HP:0006479)1.43532852
75Short femoral neck (HP:0100864)1.42474748
76Facial cleft (HP:0002006)1.41804165
77Supernumerary spleens (HP:0009799)1.39661996
78Short thorax (HP:0010306)1.39280466
79Hemiparesis (HP:0001269)1.35260375
80Hemorrhage of the eye (HP:0011885)1.33563470
81Abnormal urine output (HP:0012590)1.32700764
82Neurofibrillary tangles (HP:0002185)1.31468814
83Cystic liver disease (HP:0006706)1.31267075
84Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.30166885
85Nephropathy (HP:0000112)1.29955476
86Upper motor neuron abnormality (HP:0002127)1.24586974
87Median cleft lip (HP:0000161)1.24544738
88Aplasia/Hypoplasia of the lens (HP:0008063)1.23757671
89Aplasia/Hypoplasia of the tongue (HP:0010295)1.22233888
90Loss of speech (HP:0002371)1.22142993
91Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.21816952
92Pachygyria (HP:0001302)1.21591420
93Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.21090619
94Cerebellar dysplasia (HP:0007033)1.20625420
95Asymmetric septal hypertrophy (HP:0001670)1.20345378
96Decreased electroretinogram (ERG) amplitude (HP:0000654)1.19893622
97Bundle branch block (HP:0011710)1.19050843
98Personality changes (HP:0000751)1.17085367
99Polyuria (HP:0000103)1.16091793
100Abnormality of ocular smooth pursuit (HP:0000617)1.13877457

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.25472184
2PDK48.25472184
3TESK15.92192004
4PDK25.33470841
5PRKD35.01294908
6ICK4.26681116
7PNCK2.48297538
8PTK2B2.32727833
9WNK42.32079439
10STK392.22447465
11NEK21.95915970
12STK381.69463749
13DYRK1B1.40615504
14MAPK151.14101005
15WNK10.99689827
16PDK10.97583865
17PASK0.93267874
18TYRO30.89169072
19CDC70.84866408
20STK30.83656548
21DYRK30.81779096
22CCNB10.77238399
23IRAK10.72101136
24CAMK1G0.64179094
25TTK0.63078817
26PINK10.58057519
27CHEK20.52852129
28STK38L0.49870976
29PDPK10.49643685
30CHEK10.47901994
31TESK20.46735677
32BMPR1B0.46548375
33RIPK40.44612655
34WEE10.41920073
35EEF2K0.40710097
36LMTK20.39366360
37ATR0.39279762
38NTRK20.37973266
39MAP2K60.35995260
40PAK10.34994316
41MTOR0.33424790
42ATM0.32879119
43MUSK0.32872391
44PAK20.28681353
45IRAK20.28204899
46PRKCG0.27088113
47NEK60.25162556
48MARK20.24855507
49PRKAA10.23352298
50PLK10.23299899
51PAK40.22984552
52CAMKK10.22039483
53PLK40.21948129
54MAPKAPK50.18970899
55RPS6KB10.15964045
56SRPK10.11243470
57YES10.09643735
58PRKCZ0.09420586
59CSNK2A10.08158623
60EPHB10.07584987
61GSK3B0.07491219
62CDK20.07277866
63PRKCQ0.07253454
64CDK150.07092920
65MAP3K100.06956703
66CDK10.06878889
67WNK30.06572680
68CDK120.06461063
69CDK180.04902461
70TAOK10.04863002
71PAK60.04790307
72CSNK1D0.04705591
73CDK11A0.04480394
74AURKA0.03401872
75MAPK80.03320753
76STK100.02179298
77CDK140.02133320
78PRKACB0.02109851
79RPS6KA10.01843646
80PRKCB0.01476561
81PRKACG0.01232909
82CSNK2A20.01172617
83CDK60.00843095
84PRKG10.00051938
85MAPK1-0.0360822
86PRKG2-0.0335792
87CSK-0.0330391
88CAMK2A-0.0312229
89CSF1R-0.0295645
90BRAF-0.0267932
91PRKCA-0.0253659
92MAPK10-0.0239088
93BRSK2-0.0160986
94CDK4-0.0154747
95EGFR-0.0118866
96STK11-0.0104282
97PRKDC-0.0092775
98PDGFRB-0.0053378
99RPS6KA3-0.0040681
100CDK3-0.0009683

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.31438081
2Fatty acid biosynthesis_Homo sapiens_hsa000614.02943740
3Pyruvate metabolism_Homo sapiens_hsa006203.70508427
4Vitamin B6 metabolism_Homo sapiens_hsa007503.60232242
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.98209086
6Linoleic acid metabolism_Homo sapiens_hsa005912.85520458
7Dorso-ventral axis formation_Homo sapiens_hsa043202.76950093
8Propanoate metabolism_Homo sapiens_hsa006402.72610588
9Glucagon signaling pathway_Homo sapiens_hsa049222.70233122
10Basal transcription factors_Homo sapiens_hsa030222.57672909
11Selenocompound metabolism_Homo sapiens_hsa004502.50379350
12Carbohydrate digestion and absorption_Homo sapiens_hsa049732.20935828
13Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.16046032
14Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.03047301
15Glycerolipid metabolism_Homo sapiens_hsa005612.02855900
16Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.02497158
17Oocyte meiosis_Homo sapiens_hsa041141.98186466
18Fanconi anemia pathway_Homo sapiens_hsa034601.92483813
19PPAR signaling pathway_Homo sapiens_hsa033201.82954251
20Pentose phosphate pathway_Homo sapiens_hsa000301.73671140
21Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.65242482
22Glycerophospholipid metabolism_Homo sapiens_hsa005641.63739937
23Amphetamine addiction_Homo sapiens_hsa050311.63080022
24Huntingtons disease_Homo sapiens_hsa050161.59031439
25Fructose and mannose metabolism_Homo sapiens_hsa000511.52797350
26Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.45175700
27mRNA surveillance pathway_Homo sapiens_hsa030151.43843438
28Fat digestion and absorption_Homo sapiens_hsa049751.36419746
29Cardiac muscle contraction_Homo sapiens_hsa042601.36239408
30RNA transport_Homo sapiens_hsa030131.33286218
31Fatty acid metabolism_Homo sapiens_hsa012121.32008370
32Ether lipid metabolism_Homo sapiens_hsa005651.31525663
33Carbon metabolism_Homo sapiens_hsa012001.28110605
34Cysteine and methionine metabolism_Homo sapiens_hsa002701.27789217
35Fatty acid degradation_Homo sapiens_hsa000711.26407786
36Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.23365224
37Mineral absorption_Homo sapiens_hsa049781.21926666
38Antigen processing and presentation_Homo sapiens_hsa046121.19912231
39Renin secretion_Homo sapiens_hsa049241.15804179
40Glycosaminoglycan degradation_Homo sapiens_hsa005311.07995078
41Purine metabolism_Homo sapiens_hsa002300.99156068
42Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.91934434
43Long-term potentiation_Homo sapiens_hsa047200.90487990
44Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.90444599
45Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.88472619
46Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.84767911
47Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.84095056
48Hedgehog signaling pathway_Homo sapiens_hsa043400.80658270
49Glutathione metabolism_Homo sapiens_hsa004800.80502148
50Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.77388671
51Arachidonic acid metabolism_Homo sapiens_hsa005900.75726850
52ABC transporters_Homo sapiens_hsa020100.74333788
53Biosynthesis of amino acids_Homo sapiens_hsa012300.73113511
54Estrogen signaling pathway_Homo sapiens_hsa049150.72225841
55Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.70754163
56Chemical carcinogenesis_Homo sapiens_hsa052040.69689327
57Adipocytokine signaling pathway_Homo sapiens_hsa049200.69436424
58Central carbon metabolism in cancer_Homo sapiens_hsa052300.61679342
59Insulin secretion_Homo sapiens_hsa049110.60711255
60cGMP-PKG signaling pathway_Homo sapiens_hsa040220.60257463
61Legionellosis_Homo sapiens_hsa051340.58423482
62Collecting duct acid secretion_Homo sapiens_hsa049660.57987804
63Systemic lupus erythematosus_Homo sapiens_hsa053220.57589016
64Thyroid hormone synthesis_Homo sapiens_hsa049180.55081411
65Bile secretion_Homo sapiens_hsa049760.53910261
66Calcium signaling pathway_Homo sapiens_hsa040200.52801402
67AMPK signaling pathway_Homo sapiens_hsa041520.50487613
68Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.46442958
69Endocytosis_Homo sapiens_hsa041440.45908847
70Phosphatidylinositol signaling system_Homo sapiens_hsa040700.42762542
71VEGF signaling pathway_Homo sapiens_hsa043700.41665820
72Inositol phosphate metabolism_Homo sapiens_hsa005620.39402158
73RNA degradation_Homo sapiens_hsa030180.37155754
74Pancreatic secretion_Homo sapiens_hsa049720.37017468
75N-Glycan biosynthesis_Homo sapiens_hsa005100.34651389
76Vascular smooth muscle contraction_Homo sapiens_hsa042700.34363234
77Metabolic pathways_Homo sapiens_hsa011000.33807552
78Protein digestion and absorption_Homo sapiens_hsa049740.33264829
79Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.33180932
80Alcoholism_Homo sapiens_hsa050340.32755144
81Taste transduction_Homo sapiens_hsa047420.31618698
82Gastric acid secretion_Homo sapiens_hsa049710.31372501
83Salivary secretion_Homo sapiens_hsa049700.31304862
84Renin-angiotensin system_Homo sapiens_hsa046140.30646916
85Thyroid hormone signaling pathway_Homo sapiens_hsa049190.29987159
86Pyrimidine metabolism_Homo sapiens_hsa002400.28770810
87Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.28371683
88Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.27331402
89Circadian entrainment_Homo sapiens_hsa047130.27244318
90Synaptic vesicle cycle_Homo sapiens_hsa047210.25829001
91Pentose and glucuronate interconversions_Homo sapiens_hsa000400.25431394
92Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.24998791
93cAMP signaling pathway_Homo sapiens_hsa040240.21812012
94Wnt signaling pathway_Homo sapiens_hsa043100.18436986
95Cocaine addiction_Homo sapiens_hsa050300.16704968
96Viral carcinogenesis_Homo sapiens_hsa052030.15216509
97Sphingolipid metabolism_Homo sapiens_hsa006000.13607744
98B cell receptor signaling pathway_Homo sapiens_hsa046620.13575054
99Basal cell carcinoma_Homo sapiens_hsa052170.12615952
100Retinol metabolism_Homo sapiens_hsa008300.12126661

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »