POLR1B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nucleobase biosynthetic process (GO:0046112)5.16725825
2IMP biosynthetic process (GO:0006188)4.93220581
3purine nucleobase biosynthetic process (GO:0009113)4.80005718
4maturation of SSU-rRNA (GO:0030490)4.66599161
5nuclear pore organization (GO:0006999)4.65976422
6DNA replication initiation (GO:0006270)4.54675585
7DNA strand elongation involved in DNA replication (GO:0006271)4.53887215
8ribosome biogenesis (GO:0042254)4.48803240
9DNA unwinding involved in DNA replication (GO:0006268)4.47923695
10nuclear pore complex assembly (GO:0051292)4.47476428
11mitotic sister chromatid cohesion (GO:0007064)4.41948173
12DNA strand elongation (GO:0022616)4.36470837
13IMP metabolic process (GO:0046040)4.32923552
14establishment of integrated proviral latency (GO:0075713)4.32360934
15formation of translation preinitiation complex (GO:0001731)4.30671876
16protein localization to kinetochore (GO:0034501)4.25885056
17ribosome assembly (GO:0042255)4.21227408
18folic acid-containing compound biosynthetic process (GO:0009396)4.17020733
19ribosomal small subunit assembly (GO:0000028)4.14306294
20telomere maintenance via semi-conservative replication (GO:0032201)4.11623550
21mitotic nuclear envelope disassembly (GO:0007077)4.06271036
22ribonucleoprotein complex biogenesis (GO:0022613)4.02690766
23regulation of translational fidelity (GO:0006450)4.02401145
24DNA replication checkpoint (GO:0000076)3.93334367
25mitotic metaphase plate congression (GO:0007080)3.87596342
26ribosomal large subunit biogenesis (GO:0042273)3.86244195
27regulation of centriole replication (GO:0046599)3.79530143
28membrane disassembly (GO:0030397)3.72033862
29nuclear envelope disassembly (GO:0051081)3.72033862
30telomere maintenance via recombination (GO:0000722)3.67872273
31rRNA processing (GO:0006364)3.62097154
32DNA replication-dependent nucleosome organization (GO:0034723)3.58032081
33DNA replication-dependent nucleosome assembly (GO:0006335)3.58032081
34double-strand break repair via nonhomologous end joining (GO:0006303)3.57852048
35non-recombinational repair (GO:0000726)3.57852048
36pseudouridine synthesis (GO:0001522)3.56919866
37pore complex assembly (GO:0046931)3.55361571
38mitochondrial RNA metabolic process (GO:0000959)3.52863981
39amino acid activation (GO:0043038)3.52358619
40tRNA aminoacylation (GO:0043039)3.52358619
41mitotic recombination (GO:0006312)3.52130408
42rRNA metabolic process (GO:0016072)3.50988302
43DNA topological change (GO:0006265)3.49672871
44spliceosomal snRNP assembly (GO:0000387)3.49497269
45protein localization to chromosome, centromeric region (GO:0071459)3.47989602
46telomere maintenance via telomere lengthening (GO:0010833)3.43042404
47metaphase plate congression (GO:0051310)3.42202314
48DNA duplex unwinding (GO:0032508)3.40377498
49DNA deamination (GO:0045006)3.39972255
50regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.39369973
51DNA geometric change (GO:0032392)3.37555915
52folic acid metabolic process (GO:0046655)3.33853906
53negative regulation of chromosome segregation (GO:0051985)3.33801558
54chromatin remodeling at centromere (GO:0031055)3.32097147
55CENP-A containing nucleosome assembly (GO:0034080)3.29916323
56somatic diversification of immune receptors via somatic mutation (GO:0002566)3.29303085
57somatic hypermutation of immunoglobulin genes (GO:0016446)3.29303085
58spindle checkpoint (GO:0031577)3.28865029
59negative regulation of sister chromatid segregation (GO:0033046)3.27054939
60negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.27054939
61negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.27054939
62negative regulation of mitotic sister chromatid segregation (GO:0033048)3.27054939
63negative regulation of mitotic sister chromatid separation (GO:2000816)3.27054939
64establishment of viral latency (GO:0019043)3.24168363
65mitotic spindle checkpoint (GO:0071174)3.23256896
66regulation of spindle organization (GO:0090224)3.22486883
67nucleotide-excision repair, DNA gap filling (GO:0006297)3.22460910
68protein complex localization (GO:0031503)3.20645098
69viral transcription (GO:0019083)3.20569196
70translational termination (GO:0006415)3.20200520
71regulation of DNA endoreduplication (GO:0032875)3.20148316
72ribosomal small subunit biogenesis (GO:0042274)3.19996635
73translational initiation (GO:0006413)3.18088762
74DNA replication-independent nucleosome organization (GO:0034724)3.16470209
75DNA replication-independent nucleosome assembly (GO:0006336)3.16470209
76regulation of chromosome segregation (GO:0051983)3.13960858
77maturation of 5.8S rRNA (GO:0000460)3.13629355
78regulation of RNA export from nucleus (GO:0046831)3.11609571
79regulation of centrosome cycle (GO:0046605)3.09917191
80regulation of helicase activity (GO:0051095)3.09880943
81mitotic spindle assembly checkpoint (GO:0007094)3.09847840
82regulation of mitotic metaphase/anaphase transition (GO:0030071)3.07348693
83regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.07348693
84spindle assembly checkpoint (GO:0071173)3.06563831
85somatic recombination of immunoglobulin gene segments (GO:0016447)3.05650482
86regulation of histone H3-K9 methylation (GO:0051570)3.04840454
87transcription from mitochondrial promoter (GO:0006390)3.04817305
88translational elongation (GO:0006414)3.04064919
89kinetochore organization (GO:0051383)3.03454894
90mitotic sister chromatid segregation (GO:0000070)3.02465527
91rRNA modification (GO:0000154)3.01287985
92establishment of chromosome localization (GO:0051303)3.00668709
93tetrahydrofolate metabolic process (GO:0046653)2.99142212
94nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.98701116
95replication fork processing (GO:0031297)2.98652083
96regulation of nuclear cell cycle DNA replication (GO:0033262)2.98281299
97viral mRNA export from host cell nucleus (GO:0046784)2.98164545
98DNA synthesis involved in DNA repair (GO:0000731)2.97070509
99spliceosomal tri-snRNP complex assembly (GO:0000244)2.96542748
100DNA ligation (GO:0006266)2.95625958
101regulation of mitotic sister chromatid separation (GO:0010965)2.94968646
102regulation of mitotic sister chromatid segregation (GO:0033047)2.94968646
103regulation of sister chromatid segregation (GO:0033045)2.94968646
104regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.93906823
105attachment of spindle microtubules to kinetochore (GO:0008608)2.93674331
106peptidyl-arginine omega-N-methylation (GO:0035247)2.93607102
107regulation of translation in response to stress (GO:0043555)2.93499913
108RNA splicing, via transesterification reactions (GO:0000375)2.92499665
109transcription-coupled nucleotide-excision repair (GO:0006283)2.90502026
110negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.90492540
111mitotic chromosome condensation (GO:0007076)2.90469730
112RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.90016716
113mRNA splicing, via spliceosome (GO:0000398)2.90016716
114telomere organization (GO:0032200)2.88663098
115telomere maintenance (GO:0000723)2.88308873
116ncRNA processing (GO:0034470)2.86022849
117negative regulation of histone methylation (GO:0031061)2.85229669
118nuclear envelope organization (GO:0006998)2.84715972
119mismatch repair (GO:0006298)2.82580166
120histone exchange (GO:0043486)2.82054978
121* transcription elongation from RNA polymerase I promoter (GO:0006362)2.81864684
122tRNA methylation (GO:0030488)2.81635879
123kinetochore assembly (GO:0051382)2.81052841
124positive regulation of chromosome segregation (GO:0051984)2.81049491
125* termination of RNA polymerase I transcription (GO:0006363)2.80771564
126somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.80279564
127isotype switching (GO:0045190)2.80279564
128somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.80279564
129* cellular component biogenesis (GO:0044085)2.79385819
130ncRNA metabolic process (GO:0034660)2.77442796
131termination of RNA polymerase II transcription (GO:0006369)2.76891711
132regulation of translational termination (GO:0006449)2.76673967
133regulation of double-strand break repair via homologous recombination (GO:0010569)2.75142324
134DNA conformation change (GO:0071103)2.75023715
135tRNA aminoacylation for protein translation (GO:0006418)2.74869699
136chromatin assembly or disassembly (GO:0006333)2.74473455
137sister chromatid segregation (GO:0000819)2.73946354
138proteasome assembly (GO:0043248)2.72899208
139* DNA-templated transcription, termination (GO:0006353)2.72790388

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.28229610
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.46729311
3E2F4_17652178_ChIP-ChIP_JURKAT_Human3.61353404
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.54478199
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.52820710
6MYC_19079543_ChIP-ChIP_MESCs_Mouse3.15572546
7MYC_19030024_ChIP-ChIP_MESCs_Mouse2.87537838
8FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.86722344
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.82572778
10MYC_18358816_ChIP-ChIP_MESCs_Mouse2.80632105
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.78322888
12* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.64674423
13* ETS1_20019798_ChIP-Seq_JURKAT_Human2.64589038
14GABP_17652178_ChIP-ChIP_JURKAT_Human2.55584184
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.39199382
16NELFA_20434984_ChIP-Seq_ESCs_Mouse2.29130290
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.28840678
18XRN2_22483619_ChIP-Seq_HELA_Human2.21284663
19NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.18035189
20VDR_23849224_ChIP-Seq_CD4+_Human2.14793552
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.04154616
22AR_21909140_ChIP-Seq_LNCAP_Human1.99447970
23E2F1_21310950_ChIP-Seq_MCF-7_Human1.98713818
24* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.96301162
25MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.95690914
26* FOXP3_21729870_ChIP-Seq_TREG_Human1.95011110
27MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.94662351
28E2F1_18555785_ChIP-Seq_MESCs_Mouse1.86773892
29MYCN_18555785_ChIP-Seq_MESCs_Mouse1.86660023
30ELF1_17652178_ChIP-ChIP_JURKAT_Human1.86410316
31POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.84821177
32NANOG_18555785_ChIP-Seq_MESCs_Mouse1.84515046
33EGR1_19374776_ChIP-ChIP_THP-1_Human1.84251301
34E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.81966601
35DCP1A_22483619_ChIP-Seq_HELA_Human1.77958756
36MYC_22102868_ChIP-Seq_BL_Human1.77132193
37* GABP_19822575_ChIP-Seq_HepG2_Human1.75200718
38CIITA_25753668_ChIP-Seq_RAJI_Human1.72928962
39TTF2_22483619_ChIP-Seq_HELA_Human1.72357174
40SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.72093875
41YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.69342209
42PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.69271208
43THAP11_20581084_ChIP-Seq_MESCs_Mouse1.65390675
44NOTCH1_21737748_ChIP-Seq_TLL_Human1.60229044
45TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.57687364
46HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.57034889
47SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.54095205
48ELK1_19687146_ChIP-ChIP_HELA_Human1.52884273
49YY1_21170310_ChIP-Seq_MESCs_Mouse1.52323335
50PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.52264770
51STAT3_1855785_ChIP-Seq_MESCs_Mouse1.46266453
52ZFX_18555785_ChIP-Seq_MESCs_Mouse1.45776134
53FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.45719526
54POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.44705781
55HOXB4_20404135_ChIP-ChIP_EML_Mouse1.42425671
56* KDM5A_27292631_Chip-Seq_BREAST_Human1.42044572
57ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.40388260
58DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.33239487
59SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.31927480
60ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.28196221
61POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.27160038
62SRF_21415370_ChIP-Seq_HL-1_Mouse1.26270076
63MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.25954330
64CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.24777115
65FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.19404867
66ZNF263_19887448_ChIP-Seq_K562_Human1.19215358
67* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.18298293
68CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.16920038
69TP63_19390658_ChIP-ChIP_HaCaT_Human1.16819346
70CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.14010280
71KLF4_18555785_ChIP-Seq_MESCs_Mouse1.13755543
72SALL1_21062744_ChIP-ChIP_HESCs_Human1.11809267
73PADI4_21655091_ChIP-ChIP_MCF-7_Human1.11045732
74TFEB_21752829_ChIP-Seq_HELA_Human1.09891347
75SOX2_18555785_ChIP-Seq_MESCs_Mouse1.08590406
76SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.07608783
77E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.05095579
78DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.04928280
79SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.99959986
80KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.99862026
81VDR_21846776_ChIP-Seq_THP-1_Human0.99387780
82CHD1_26751641_Chip-Seq_LNCaP_Human0.98695239
83CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.98266477
84SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.97704821
85NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.97495836
86CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.96360503
87ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.95267957
88BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.93895791
89SOX17_20123909_ChIP-Seq_XEN_Mouse0.92944850
90CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.91690991
91NANOG_16153702_ChIP-ChIP_HESCs_Human0.91365499
92KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.90812565
93KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.90812565
94KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.90812565
95TCF3_18692474_ChIP-Seq_MEFs_Mouse0.90589108
96* MYC_18940864_ChIP-ChIP_HL60_Human0.89985985
97GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.89982039
98SPI1_23547873_ChIP-Seq_NB4_Human0.89942978
99RBPJ_22232070_ChIP-Seq_NCS_Mouse0.89116660
100KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.88548109
101CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.87965926
102EWS_26573619_Chip-Seq_HEK293_Human0.87043307
103* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.85163404
104NANOG_21062744_ChIP-ChIP_HESCs_Human0.84259135
105HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.83147032
106PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.83099026
107NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.81792812
108HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.80227848
109ESR1_15608294_ChIP-ChIP_MCF-7_Human0.79960681
110SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.78254310
111* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.73591455
112ELK1_22589737_ChIP-Seq_MCF10A_Human0.73138140
113SOX2_16153702_ChIP-ChIP_HESCs_Human0.72924854
114TCF3_18692474_ChIP-Seq_MESCs_Mouse0.71617814
115ELF5_23300383_ChIP-Seq_T47D_Human0.68468029
116TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.67960735
117TBX5_21415370_ChIP-Seq_HL-1_Mouse0.65316514

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.23868856
2MP0010094_abnormal_chromosome_stability4.74954930
3MP0008057_abnormal_DNA_replication4.50695989
4* MP0003111_abnormal_nucleus_morphology4.47989131
5* MP0004957_abnormal_blastocyst_morpholog4.22378130
6MP0003077_abnormal_cell_cycle3.94969257
7MP0008058_abnormal_DNA_repair3.67003461
8MP0002396_abnormal_hematopoietic_system2.99558443
9MP0008007_abnormal_cellular_replicative2.77172653
10MP0001730_embryonic_growth_arrest2.43568650
11MP0003941_abnormal_skin_development2.39588187
12MP0008932_abnormal_embryonic_tissue2.38251956
13MP0000350_abnormal_cell_proliferation2.26950235
14MP0003786_premature_aging2.21266386
15MP0010352_gastrointestinal_tract_polyps2.19487203
16MP0003123_paternal_imprinting2.07503657
17MP0008877_abnormal_DNA_methylation1.91629878
18MP0005380_embryogenesis_phenotype1.90203384
19MP0001672_abnormal_embryogenesis/_devel1.90203384
20MP0010307_abnormal_tumor_latency1.86191859
21MP0000490_abnormal_crypts_of1.82408425
22MP0003806_abnormal_nucleotide_metabolis1.72891863
23MP0003984_embryonic_growth_retardation1.72302774
24MP0001697_abnormal_embryo_size1.70365375
25MP0002088_abnormal_embryonic_growth/wei1.67852285
26MP0002877_abnormal_melanocyte_morpholog1.67569002
27MP0010234_abnormal_vibrissa_follicle1.67414693
28MP0004808_abnormal_hematopoietic_stem1.64752586
29MP0009333_abnormal_splenocyte_physiolog1.62155566
30MP0003763_abnormal_thymus_physiology1.61669060
31* MP0002080_prenatal_lethality1.59482560
32MP0005187_abnormal_penis_morphology1.56508650
33MP0003718_maternal_effect1.55475654
34MP0002086_abnormal_extraembryonic_tissu1.52317771
35MP0001986_abnormal_taste_sensitivity1.52189491
36MP0003567_abnormal_fetal_cardiomyocyte1.51867922
37MP0000313_abnormal_cell_death1.51717523
38* MP0002085_abnormal_embryonic_tissue1.48127773
39MP0002084_abnormal_developmental_patter1.47490419
40MP0002019_abnormal_tumor_incidence1.44891511
41MP0004197_abnormal_fetal_growth/weight/1.42848187
42MP0001545_abnormal_hematopoietic_system1.36273739
43MP0005397_hematopoietic_system_phenotyp1.36273739
44MP0002009_preneoplasia1.31538568
45MP0001661_extended_life_span1.29953329
46MP0003890_abnormal_embryonic-extraembry1.26807987
47MP0004233_abnormal_muscle_weight1.26005109
48MP0000703_abnormal_thymus_morphology1.25677926
49MP0002398_abnormal_bone_marrow1.23979618
50MP0005076_abnormal_cell_differentiation1.19211177
51MP0005220_abnormal_exocrine_pancreas1.17985010
52MP0000689_abnormal_spleen_morphology1.16931988
53MP0006292_abnormal_olfactory_placode1.16841944
54MP0002722_abnormal_immune_system1.16720834
55MP0002210_abnormal_sex_determination1.11977333
56MP0008995_early_reproductive_senescence1.10133360
57MP0002796_impaired_skin_barrier1.09198694
58MP0001293_anophthalmia1.08992263
59MP0005501_abnormal_skin_physiology1.02824293
60MP0001145_abnormal_male_reproductive1.01916424
61MP0002132_abnormal_respiratory_system0.98432067
62MP0002234_abnormal_pharynx_morphology0.98184309
63MP0001853_heart_inflammation0.97658150
64MP0006036_abnormal_mitochondrial_physio0.97382163
65MP0003868_abnormal_feces_composition0.95944437
66MP0003937_abnormal_limbs/digits/tail_de0.95520111
67MP0002429_abnormal_blood_cell0.94591978
68MP0003566_abnormal_cell_adhesion0.90241392
69MP0003121_genomic_imprinting0.89457699
70MP0005075_abnormal_melanosome_morpholog0.87301184
71MP0000579_abnormal_nail_morphology0.86980834
72MP0001835_abnormal_antigen_presentation0.86745611
73MP0001929_abnormal_gametogenesis0.85368875
74MP0000358_abnormal_cell_content/0.85001637
75MP0000653_abnormal_sex_gland0.83165902
76MP0000716_abnormal_immune_system0.82474314
77MP0005384_cellular_phenotype0.81846292
78MP0000371_diluted_coat_color0.81261169
79MP0001119_abnormal_female_reproductive0.80529107
80MP0009278_abnormal_bone_marrow0.79679954
81MP0001915_intracranial_hemorrhage0.79598619
82MP0002006_tumorigenesis0.79187091
83MP0003315_abnormal_perineum_morphology0.79046536
84MP0005621_abnormal_cell_physiology0.78576350
85MP0001873_stomach_inflammation0.78092819
86MP0004185_abnormal_adipocyte_glucose0.77306008
87MP0002697_abnormal_eye_size0.77261539
88MP0001919_abnormal_reproductive_system0.77205475
89MP0003186_abnormal_redox_activity0.76937238
90MP0003221_abnormal_cardiomyocyte_apopto0.76509891
91MP0009672_abnormal_birth_weight0.76328691
92MP0009053_abnormal_anal_canal0.75274530
93MP0001800_abnormal_humoral_immune0.74969388
94MP0000427_abnormal_hair_cycle0.73859406
95MP0000858_altered_metastatic_potential0.73277747
96MP0005671_abnormal_response_to0.72224715
97MP0002111_abnormal_tail_morphology0.71948968
98MP0001727_abnormal_embryo_implantation0.71620057
99MP0002405_respiratory_system_inflammati0.71255607
100MP0000477_abnormal_intestine_morphology0.70225152
101MP0000762_abnormal_tongue_morphology0.69901155
102MP0003943_abnormal_hepatobiliary_system0.69751598
103MP0002075_abnormal_coat/hair_pigmentati0.68729021
104MP0009703_decreased_birth_body0.68717910
105MP0002166_altered_tumor_susceptibility0.68656977
106MP0002160_abnormal_reproductive_system0.68482168
107MP0000465_gastrointestinal_hemorrhage0.67749959
108MP0001286_abnormal_eye_development0.66617152
109MP0005023_abnormal_wound_healing0.66285748
110MP0003119_abnormal_digestive_system0.65353664
111MP0004133_heterotaxia0.64180985
112MP0004782_abnormal_surfactant_physiolog0.63846036
113MP0005389_reproductive_system_phenotype0.63496364
114MP0010030_abnormal_orbit_morphology0.62601285
115MP0000537_abnormal_urethra_morphology0.62127687
116MP0002420_abnormal_adaptive_immunity0.62103989
117MP0005266_abnormal_metabolism0.61593869
118MP0005395_other_phenotype0.61485654
119MP0010155_abnormal_intestine_physiology0.61002881
120MP0010678_abnormal_skin_adnexa0.60969101
121MP0003699_abnormal_female_reproductive0.60491919
122MP0001819_abnormal_immune_cell0.60326239
123MP0001881_abnormal_mammary_gland0.59645867
124MP0002452_abnormal_antigen_presenting0.59234186
125MP0002233_abnormal_nose_morphology0.59029525
126MP0004264_abnormal_extraembryonic_tissu0.58919650
127MP0009697_abnormal_copulation0.58526583
128MP0008770_decreased_survivor_rate0.57635839
129MP0002163_abnormal_gland_morphology0.56650497
130MP0000627_abnormal_mammary_gland0.56629154
131MP0000647_abnormal_sebaceous_gland0.56449397
132MP0002092_abnormal_eye_morphology0.56432235
133MP0006035_abnormal_mitochondrial_morpho0.55837208
134MP0001186_pigmentation_phenotype0.54208691
135MP0002095_abnormal_skin_pigmentation0.53357013
136MP0002723_abnormal_immune_serum0.52911428
137MP0002938_white_spotting0.51934253

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.07319121
2Reticulocytopenia (HP:0001896)4.13468595
3Chromsome breakage (HP:0040012)4.06371089
4Chromosomal breakage induced by crosslinking agents (HP:0003221)4.03161800
5Abnormality of cells of the erythroid lineage (HP:0012130)3.89556003
6Ependymoma (HP:0002888)3.88532583
7Abnormal number of erythroid precursors (HP:0012131)3.83715805
8Breast hypoplasia (HP:0003187)3.45898190
9Medulloblastoma (HP:0002885)3.45194200
10Colon cancer (HP:0003003)3.33670933
11Abnormality of chromosome stability (HP:0003220)3.32913330
12Progressive external ophthalmoplegia (HP:0000590)3.31760537
13Oral leukoplakia (HP:0002745)3.29566680
14Aplastic anemia (HP:0001915)3.29342067
15Microvesicular hepatic steatosis (HP:0001414)3.25916743
16Selective tooth agenesis (HP:0001592)3.22643176
17Agnosia (HP:0010524)3.18656873
18Abnormality of the preputium (HP:0100587)3.18030064
19Degeneration of anterior horn cells (HP:0002398)3.17342392
20Abnormality of the anterior horn cell (HP:0006802)3.17342392
21Patellar aplasia (HP:0006443)3.15459097
22Meckel diverticulum (HP:0002245)3.11676881
23Nephroblastoma (Wilms tumor) (HP:0002667)3.03723049
24Abnormality of the ileum (HP:0001549)2.95184485
25Rough bone trabeculation (HP:0100670)2.93087382
26Impulsivity (HP:0100710)2.91813763
27Aplasia/Hypoplasia of the patella (HP:0006498)2.91736647
28Myelodysplasia (HP:0002863)2.90922248
29Volvulus (HP:0002580)2.88353421
30Aplasia/Hypoplasia of the uvula (HP:0010293)2.83013543
31Embryonal renal neoplasm (HP:0011794)2.79058115
32Rhabdomyosarcoma (HP:0002859)2.78258377
33Absent thumb (HP:0009777)2.75129440
34Chronic otitis media (HP:0000389)2.74276359
35Carpal bone hypoplasia (HP:0001498)2.72773765
36Thrombocytosis (HP:0001894)2.70057246
37Gonadotropin excess (HP:0000837)2.69082213
38Cerebral hypomyelination (HP:0006808)2.68235111
39Abnormality of alanine metabolism (HP:0010916)2.66252240
40Hyperalaninemia (HP:0003348)2.66252240
41Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.66252240
42Premature graying of hair (HP:0002216)2.65680700
43Bone marrow hypocellularity (HP:0005528)2.64891796
44Amaurosis fugax (HP:0100576)2.62404430
45Abnormality of glycolysis (HP:0004366)2.62054546
46Abnormality of pyrimidine metabolism (HP:0004353)2.52719218
47Absent radius (HP:0003974)2.52433196
48Basal cell carcinoma (HP:0002671)2.51543110
49Progressive muscle weakness (HP:0003323)2.50991780
50Macrocytic anemia (HP:0001972)2.49808869
51Increased serum pyruvate (HP:0003542)2.44108897
52Small intestinal stenosis (HP:0012848)2.43228655
53Duodenal stenosis (HP:0100867)2.43228655
54Urethral obstruction (HP:0000796)2.42316965
55Abnormality of the astrocytes (HP:0100707)2.42007171
56Astrocytoma (HP:0009592)2.42007171
57Ectopic kidney (HP:0000086)2.41712955
58Pallor (HP:0000980)2.41538815
59Glioma (HP:0009733)2.41506438
60Abnormal number of incisors (HP:0011064)2.40973411
6111 pairs of ribs (HP:0000878)2.39146439
62Cellular immunodeficiency (HP:0005374)2.37199690
63Aplasia involving forearm bones (HP:0009822)2.36053741
64Absent forearm bone (HP:0003953)2.36053741
65Neoplasm of the pancreas (HP:0002894)2.35233126
66Abnormality of the labia minora (HP:0012880)2.33970586
67Protruding tongue (HP:0010808)2.30393869
68Supernumerary spleens (HP:0009799)2.28521493
69Duplicated collecting system (HP:0000081)2.27767048
70Abnormality of methionine metabolism (HP:0010901)2.25983955
71Abnormality of DNA repair (HP:0003254)2.25680742
72Tracheoesophageal fistula (HP:0002575)2.24108306
73Lymphoma (HP:0002665)2.23229521
74Sloping forehead (HP:0000340)2.19345191
75Multiple enchondromatosis (HP:0005701)2.17446029
76Pancytopenia (HP:0001876)2.16927402
77Trismus (HP:0000211)2.15703400
78Hypergonadotropic hypogonadism (HP:0000815)2.15148742
79Squamous cell carcinoma (HP:0002860)2.14728492
80Abnormal spermatogenesis (HP:0008669)2.11769749
81Horseshoe kidney (HP:0000085)2.10809222
82IgM deficiency (HP:0002850)2.08842183
83Increased serum lactate (HP:0002151)2.06892446
84Neoplasm of striated muscle (HP:0009728)2.05219253
85Abnormality of the duodenum (HP:0002246)2.04287539
86Proximal placement of thumb (HP:0009623)2.04277699
87Insidious onset (HP:0003587)2.02779726
88Termporal pattern (HP:0011008)2.02779726
89Prominent nose (HP:0000448)2.01626498
90Abnormality of the carotid arteries (HP:0005344)2.01387571
91Deviation of the thumb (HP:0009603)2.00241538
92Clubbing of toes (HP:0100760)2.00197008
93Ureteral duplication (HP:0000073)1.99986089
94Septate vagina (HP:0001153)1.99412776
95Abnormality of the renal collecting system (HP:0004742)1.99308619
96Abnormal trabecular bone morphology (HP:0100671)1.98864018
97Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.95982415
98Cafe-au-lait spot (HP:0000957)1.95218523
99Neoplasm of the oral cavity (HP:0100649)1.92404357
100Poikiloderma (HP:0001029)1.91419434
101Premature ovarian failure (HP:0008209)1.90413692
102Microretrognathia (HP:0000308)1.90291624
103Cortical dysplasia (HP:0002539)1.89570641
104Secondary amenorrhea (HP:0000869)1.89277416
105Acute myeloid leukemia (HP:0004808)1.87947752
106Entropion (HP:0000621)1.87509232
107Choanal atresia (HP:0000453)1.84765942
108Atresia of the external auditory canal (HP:0000413)1.84505423
109Abnormality of reticulocytes (HP:0004312)1.82739573
110Triphalangeal thumb (HP:0001199)1.82612235
111Postnatal microcephaly (HP:0005484)1.81963981
112Neuroblastic tumors (HP:0004376)1.81590503
113Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.81590503
114Neuroblastoma (HP:0003006)1.81590503
115Primitive neuroectodermal tumor (HP:0030065)1.81590503
116Overlapping toe (HP:0001845)1.81298728
117Spastic diplegia (HP:0001264)1.80822776
118Sensory axonal neuropathy (HP:0003390)1.80353297
119Asplenia (HP:0001746)1.77832968
120Abnormal lung lobation (HP:0002101)1.77628545
121Abnormal biliary tract morphology (HP:0012440)1.76834274
122CNS hypomyelination (HP:0003429)1.76085761
123Biliary tract neoplasm (HP:0100574)1.75359915
124Deep philtrum (HP:0002002)1.75185697
125Facial cleft (HP:0002006)1.74863996
126Increased nuchal translucency (HP:0010880)1.74689393
127Neoplasm of the colon (HP:0100273)1.74583224
128Aplasia/Hypoplasia of the sacrum (HP:0008517)1.74042440
129Atrophy/Degeneration involving motor neurons (HP:0007373)1.73676697
130Short thumb (HP:0009778)1.73492386
131Abnormality of the umbilical cord (HP:0010881)1.73174794
132Rib fusion (HP:0000902)1.73101394
133Glossoptosis (HP:0000162)1.72420320
134Hypoplasia of the pons (HP:0012110)1.71931229
135Radioulnar synostosis (HP:0002974)1.71297025
136Increased hepatocellular lipid droplets (HP:0006565)1.70386266
137Limb hypertonia (HP:0002509)1.69739986
138Abnormality of serum amino acid levels (HP:0003112)1.68089515
139Lipid accumulation in hepatocytes (HP:0006561)1.67022829
140Abnormality of the pons (HP:0007361)1.64762866
141Abnormality of the fetal cardiovascular system (HP:0010948)1.64388615
142Abnormal umbilical cord blood vessels (HP:0011403)1.64388615
143Single umbilical artery (HP:0001195)1.64388615
144Embryonal neoplasm (HP:0002898)1.64207094
145Abnormality of homocysteine metabolism (HP:0010919)1.62259845

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE14.14200662
2BUB13.78362685
3CDC73.67678774
4TSSK63.41211393
5PBK3.41157532
6EIF2AK13.10908363
7SRPK12.66671849
8CDK122.43631038
9NEK22.42752180
10TTK2.25086745
11EEF2K2.18974883
12MST42.11282333
13PASK2.07441051
14MKNK12.06026527
15BRSK22.04274881
16ACVR1B2.01927109
17CASK1.99644374
18NEK11.91515249
19NME21.90426481
20MKNK21.90305161
21RPS6KB21.86588262
22EIF2AK31.84539080
23CDK71.81719688
24PLK11.81399620
25STK161.79864786
26ATR1.76805517
27EPHA21.74212653
28SMG11.67482164
29PLK31.63215152
30PLK41.58306354
31VRK11.56144984
32MST1R1.55118690
33AURKB1.54080451
34ICK1.46996339
35CDK41.44999950
36ZAK1.42180547
37TRIM281.41015762
38TLK11.40083470
39MAP4K11.34109867
40CHEK21.31359905
41PIM11.30446478
42NME11.30326056
43CHEK11.29715130
44MAP3K81.29455326
45VRK21.28246061
46TGFBR11.25422716
47STK101.22979704
48DYRK31.15168990
49RPS6KA41.14614757
50PIM21.13886894
51FLT31.13136451
52INSRR1.11260576
53ALK1.10666074
54BRSK11.09180424
55BRD41.04914432
56STK41.01869622
57NUAK11.01770789
58AURKA0.99310557
59MAP2K30.97697309
60CCNB10.96162615
61ERBB40.95424644
62TAF10.95300359
63ATM0.94105994
64CDK20.93949631
65SCYL20.88201238
66MAPKAPK30.85773381
67MAP3K140.84224033
68PAK40.84015403
69TAOK20.81099748
70ZAP700.80898177
71MET0.74299130
72TESK20.72316273
73PDK20.71967499
74CSNK2A20.71899221
75JAK30.70914942
76PKN20.70587333
77STK30.69451719
78TXK0.64218005
79CSNK2A10.63303476
80LATS10.63010875
81CDK10.62901955
82BCR0.60754903
83EIF2AK20.60754495
84RPS6KA50.57153052
85CHUK0.56581921
86MAP3K100.56044415
87BTK0.55562067
88CDK60.54308019
89IRAK30.53777313
90MTOR0.53777116
91TEC0.53069063
92LRRK20.52670311
93BRAF0.51637611
94CDK80.51514333
95PAK10.51150467
96MELK0.48433324
97RPS6KB10.46736601
98CSF1R0.46648635
99PRKCI0.46562920
100IKBKB0.45850709
101MAP3K110.45627018
102CLK10.44889132
103MAP3K30.44119125
104STK240.44112732
105AKT30.42804150
106CSNK1E0.41902846
107PNCK0.39861139
108PAK20.38362037
109MAP3K50.37848058
110DAPK10.37178304
111KIT0.36803038
112NEK60.36633153
113AKT20.36276082
114PRKDC0.35698224
115CDK90.34894110
116RPS6KA60.33520931
117RPS6KA10.30761806
118TYK20.30475298
119RPS6KL10.30187212
120RPS6KC10.30187212
121MAPK140.29325509
122STK390.28642496
123STK38L0.28559227
124RAF10.27201817
125FGFR10.26204747
126MAPK110.26178411
127MAPKAPK50.23102736
128PLK20.22148803
129ERBB30.21230602
130CSNK1G10.19748002
131NEK90.18350209

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.74049468
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.15605135
3Mismatch repair_Homo sapiens_hsa034304.12223678
4RNA transport_Homo sapiens_hsa030133.31597105
5Spliceosome_Homo sapiens_hsa030403.25020987
6One carbon pool by folate_Homo sapiens_hsa006703.15263365
7* RNA polymerase_Homo sapiens_hsa030203.12593578
8Ribosome_Homo sapiens_hsa030103.06674045
9Base excision repair_Homo sapiens_hsa034102.96609641
10Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.84164051
11Homologous recombination_Homo sapiens_hsa034402.82018492
12Nucleotide excision repair_Homo sapiens_hsa034202.76139407
13Proteasome_Homo sapiens_hsa030502.72312988
14Cell cycle_Homo sapiens_hsa041102.45907570
15* Pyrimidine metabolism_Homo sapiens_hsa002402.30689899
16Fanconi anemia pathway_Homo sapiens_hsa034602.26424996
17Non-homologous end-joining_Homo sapiens_hsa034502.11191318
18RNA degradation_Homo sapiens_hsa030181.90964175
19mRNA surveillance pathway_Homo sapiens_hsa030151.87225962
20Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.84129497
21Basal transcription factors_Homo sapiens_hsa030221.73723476
22p53 signaling pathway_Homo sapiens_hsa041151.46766782
23* Purine metabolism_Homo sapiens_hsa002301.28892850
24Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.23662494
25Vitamin B6 metabolism_Homo sapiens_hsa007501.21927921
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.20751295
27Epstein-Barr virus infection_Homo sapiens_hsa051691.18388267
28Cyanoamino acid metabolism_Homo sapiens_hsa004601.15928972
29Systemic lupus erythematosus_Homo sapiens_hsa053221.14705383
30Pyruvate metabolism_Homo sapiens_hsa006201.13654380
31Selenocompound metabolism_Homo sapiens_hsa004501.10243988
32Steroid biosynthesis_Homo sapiens_hsa001001.08557139
33Cysteine and methionine metabolism_Homo sapiens_hsa002701.07052740
34Biosynthesis of amino acids_Homo sapiens_hsa012301.07015398
35Herpes simplex infection_Homo sapiens_hsa051681.00403334
36Pentose phosphate pathway_Homo sapiens_hsa000301.00165582
37Antigen processing and presentation_Homo sapiens_hsa046120.98334126
38Propanoate metabolism_Homo sapiens_hsa006400.97783600
39Drug metabolism - other enzymes_Homo sapiens_hsa009830.96341882
40Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.93920865
41Viral carcinogenesis_Homo sapiens_hsa052030.92287651
42Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.87387074
43Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.83943487
44Protein export_Homo sapiens_hsa030600.83410601
45Folate biosynthesis_Homo sapiens_hsa007900.82331312
46Fatty acid elongation_Homo sapiens_hsa000620.76199772
47Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.73062585
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.70728614
49HTLV-I infection_Homo sapiens_hsa051660.68529854
50Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.66957124
51Primary immunodeficiency_Homo sapiens_hsa053400.65867937
52Legionellosis_Homo sapiens_hsa051340.64236113
53Allograft rejection_Homo sapiens_hsa053300.62248260
54MicroRNAs in cancer_Homo sapiens_hsa052060.61953569
55Sulfur relay system_Homo sapiens_hsa041220.61281971
56Transcriptional misregulation in cancer_Homo sapiens_hsa052020.61155356
57NF-kappa B signaling pathway_Homo sapiens_hsa040640.56915398
58Fructose and mannose metabolism_Homo sapiens_hsa000510.56541417
59Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.55236885
602-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.55178544
61Oocyte meiosis_Homo sapiens_hsa041140.55174132
62Measles_Homo sapiens_hsa051620.55088220
63Thyroid cancer_Homo sapiens_hsa052160.52466591
64Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.52085474
65Carbon metabolism_Homo sapiens_hsa012000.50957943
66Small cell lung cancer_Homo sapiens_hsa052220.47416348
67Fatty acid metabolism_Homo sapiens_hsa012120.45339829
68Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.44934325
69Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.43745906
70Apoptosis_Homo sapiens_hsa042100.42442220
71Intestinal immune network for IgA production_Homo sapiens_hsa046720.41576257
72Prostate cancer_Homo sapiens_hsa052150.40085235
73Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.37826567
74Acute myeloid leukemia_Homo sapiens_hsa052210.37684207
75Asthma_Homo sapiens_hsa053100.37175545
76Galactose metabolism_Homo sapiens_hsa000520.37090097
77Glutathione metabolism_Homo sapiens_hsa004800.35844152
78Notch signaling pathway_Homo sapiens_hsa043300.35743338
79Hematopoietic cell lineage_Homo sapiens_hsa046400.34778664
80Fatty acid biosynthesis_Homo sapiens_hsa000610.33474738
81Pancreatic cancer_Homo sapiens_hsa052120.32525086
82Influenza A_Homo sapiens_hsa051640.32277033
83Bladder cancer_Homo sapiens_hsa052190.31970148
84Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.30156520
85Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29874322
86Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.29725612
87N-Glycan biosynthesis_Homo sapiens_hsa005100.28494765
88Hepatitis B_Homo sapiens_hsa051610.27710994
89Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.26686425
90Central carbon metabolism in cancer_Homo sapiens_hsa052300.26421882
91Jak-STAT signaling pathway_Homo sapiens_hsa046300.25822711
92Non-small cell lung cancer_Homo sapiens_hsa052230.25660222
93Lysine degradation_Homo sapiens_hsa003100.25177102
94Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.24943759
95Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.24600584
96RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.24382705
97Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.23747329
98Autoimmune thyroid disease_Homo sapiens_hsa053200.23335397
99Chronic myeloid leukemia_Homo sapiens_hsa052200.23200862
100Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.22636688
101Hippo signaling pathway_Homo sapiens_hsa043900.22484151
102HIF-1 signaling pathway_Homo sapiens_hsa040660.22374350
103Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.22148657
104Vitamin digestion and absorption_Homo sapiens_hsa049770.21284070
105NOD-like receptor signaling pathway_Homo sapiens_hsa046210.20801820
106Adherens junction_Homo sapiens_hsa045200.19739811
107Shigellosis_Homo sapiens_hsa051310.19538469
108Huntingtons disease_Homo sapiens_hsa050160.19525772
109TGF-beta signaling pathway_Homo sapiens_hsa043500.19256789
110mTOR signaling pathway_Homo sapiens_hsa041500.18538654
111Leishmaniasis_Homo sapiens_hsa051400.18458472
112Basal cell carcinoma_Homo sapiens_hsa052170.17672827
113Alcoholism_Homo sapiens_hsa050340.17497179
114* Metabolic pathways_Homo sapiens_hsa011000.17377004
115Melanoma_Homo sapiens_hsa052180.17101144
116Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.15262904
117Viral myocarditis_Homo sapiens_hsa054160.14967595
118Arginine biosynthesis_Homo sapiens_hsa002200.14709011
119Colorectal cancer_Homo sapiens_hsa052100.14617278
120Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.14457310
121T cell receptor signaling pathway_Homo sapiens_hsa046600.14440269
122Arginine and proline metabolism_Homo sapiens_hsa003300.14047569
123Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.08851366
124Sulfur metabolism_Homo sapiens_hsa009200.08316524
125Starch and sucrose metabolism_Homo sapiens_hsa005000.07580023
126Maturity onset diabetes of the young_Homo sapiens_hsa049500.07578714
127Endometrial cancer_Homo sapiens_hsa052130.06589713

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