POLE3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA strand elongation involved in DNA replication (GO:0006271)4.97728540
2ribosomal small subunit assembly (GO:0000028)4.79791431
3telomere maintenance via semi-conservative replication (GO:0032201)4.75538361
4DNA strand elongation (GO:0022616)4.71525383
5DNA deamination (GO:0045006)4.57714985
6viral transcription (GO:0019083)4.46014936
7DNA replication initiation (GO:0006270)4.44028593
8DNA replication checkpoint (GO:0000076)4.38664923
9translational termination (GO:0006415)4.38585112
10maturation of SSU-rRNA (GO:0030490)4.36009565
11establishment of integrated proviral latency (GO:0075713)4.29380301
12telomere maintenance via recombination (GO:0000722)4.21129293
13DNA unwinding involved in DNA replication (GO:0006268)4.13748056
14formation of translation preinitiation complex (GO:0001731)4.09093277
15ribosomal small subunit biogenesis (GO:0042274)4.05507473
16mitotic recombination (GO:0006312)4.02284442
17mitotic metaphase plate congression (GO:0007080)4.02208719
18translational elongation (GO:0006414)4.00337853
19CENP-A containing nucleosome assembly (GO:0034080)3.99317430
20deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.95754437
21protein localization to kinetochore (GO:0034501)3.92154081
22translational initiation (GO:0006413)3.88984340
23proteasome assembly (GO:0043248)3.88435324
24chromatin remodeling at centromere (GO:0031055)3.87788162
25kinetochore organization (GO:0051383)3.86261411
26nucleobase biosynthetic process (GO:0046112)3.83902807
27purine nucleobase biosynthetic process (GO:0009113)3.83609280
28SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.83041956
29ribosomal large subunit biogenesis (GO:0042273)3.82589089
30cotranslational protein targeting to membrane (GO:0006613)3.74297353
31nucleotide-excision repair, DNA gap filling (GO:0006297)3.72615776
32protein targeting to ER (GO:0045047)3.72270426
33DNA ligation (GO:0006266)3.70757692
34nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.69375830
35DNA replication-independent nucleosome organization (GO:0034724)3.69237500
36DNA replication-independent nucleosome assembly (GO:0006336)3.69237500
37regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.66506756
38telomere maintenance via telomere lengthening (GO:0010833)3.64125021
39ribonucleoprotein complex biogenesis (GO:0022613)3.63554479
40protein localization to chromosome, centromeric region (GO:0071459)3.63443973
41spliceosomal snRNP assembly (GO:0000387)3.62438946
42kinetochore assembly (GO:0051382)3.60645086
43negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.56841624
44nuclear pore complex assembly (GO:0051292)3.56241796
45establishment of protein localization to endoplasmic reticulum (GO:0072599)3.53900615
46protein localization to endoplasmic reticulum (GO:0070972)3.52450957
47DNA replication-dependent nucleosome organization (GO:0034723)3.50948052
48DNA replication-dependent nucleosome assembly (GO:0006335)3.50948052
49mitotic nuclear envelope disassembly (GO:0007077)3.50245629
50metaphase plate congression (GO:0051310)3.49757630
51negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.48988159
52anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.47507994
53ribosome biogenesis (GO:0042254)3.44969621
54cellular protein complex disassembly (GO:0043624)3.44170566
55viral life cycle (GO:0019058)3.43526188
56establishment of viral latency (GO:0019043)3.42126862
57regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.41381060
58attachment of spindle microtubules to kinetochore (GO:0008608)3.40420940
59DNA topological change (GO:0006265)3.38015409
60negative regulation of mRNA processing (GO:0050686)3.37304627
61positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.35268484
62histone exchange (GO:0043486)3.31684128
63ribosome assembly (GO:0042255)3.29489109
64establishment of chromosome localization (GO:0051303)3.28262777
65translation (GO:0006412)3.26889207
66nucleobase-containing small molecule interconversion (GO:0015949)3.26624790
67rRNA processing (GO:0006364)3.26330442
68nuclear pore organization (GO:0006999)3.25014443
69mitotic sister chromatid cohesion (GO:0007064)3.24143435
70negative regulation of RNA splicing (GO:0033119)3.23704981
71folic acid-containing compound biosynthetic process (GO:0009396)3.22305800
72transcription-coupled nucleotide-excision repair (GO:0006283)3.21144993
73membrane disassembly (GO:0030397)3.20395840
74nuclear envelope disassembly (GO:0051081)3.20395840
75negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.19955645
76negative regulation of ligase activity (GO:0051352)3.19955645
77mitotic chromosome condensation (GO:0007076)3.18024139
78non-recombinational repair (GO:0000726)3.15288369
79double-strand break repair via nonhomologous end joining (GO:0006303)3.15288369
80rRNA metabolic process (GO:0016072)3.14439134
81spliceosomal complex assembly (GO:0000245)3.12901850
82protein complex disassembly (GO:0043241)3.11766981
83DNA catabolic process, exonucleolytic (GO:0000738)3.10628304
84IMP metabolic process (GO:0046040)3.09772062
85G1/S transition of mitotic cell cycle (GO:0000082)3.07820996
86cell cycle G1/S phase transition (GO:0044843)3.07820996
87regulation of mitochondrial translation (GO:0070129)3.07335500
88IMP biosynthetic process (GO:0006188)3.07139773
89pseudouridine synthesis (GO:0001522)3.06128144
90deoxyribonucleotide biosynthetic process (GO:0009263)3.06105919
91folic acid metabolic process (GO:0046655)3.05511070
92nuclear-transcribed mRNA catabolic process (GO:0000956)3.02636114
93regulation of double-strand break repair via homologous recombination (GO:0010569)3.02511180
94negative regulation of mRNA metabolic process (GO:1903312)3.01843479
95spindle checkpoint (GO:0031577)3.01238284
96pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.00942925
977-methylguanosine mRNA capping (GO:0006370)3.00280729
98telomere organization (GO:0032200)2.99651493
99exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.99280633
100mitotic sister chromatid segregation (GO:0000070)2.98417840
101telomere maintenance (GO:0000723)2.97665149
102base-excision repair (GO:0006284)2.97372447
1037-methylguanosine RNA capping (GO:0009452)2.96530252
104RNA capping (GO:0036260)2.96530252
1052-deoxyribonucleotide biosynthetic process (GO:0009265)2.95903653
106deoxyribose phosphate biosynthetic process (GO:0046385)2.95903653
107positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.95864410
108macromolecular complex disassembly (GO:0032984)2.95144744
109somatic diversification of immune receptors via somatic mutation (GO:0002566)2.95104630
110somatic hypermutation of immunoglobulin genes (GO:0016446)2.95104630
111regulation of centriole replication (GO:0046599)2.94992929
112regulation of spindle organization (GO:0090224)2.94702727
113tRNA aminoacylation for protein translation (GO:0006418)2.92341695
114pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.92199300
115chromosome segregation (GO:0007059)2.92092050
116sister chromatid segregation (GO:0000819)2.90926483
117negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.90291515
118negative regulation of sister chromatid segregation (GO:0033046)2.90291515
119negative regulation of mitotic sister chromatid separation (GO:2000816)2.90291515
120negative regulation of mitotic sister chromatid segregation (GO:0033048)2.90291515
121amino acid activation (GO:0043038)2.89580571
122tRNA aminoacylation (GO:0043039)2.89580571
123viral mRNA export from host cell nucleus (GO:0046784)2.89553090
124DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.89475053
125negative regulation of chromosome segregation (GO:0051985)2.89415797
126spindle assembly checkpoint (GO:0071173)2.87827652
127negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.87616013
128protein K6-linked ubiquitination (GO:0085020)2.87330051
129positive regulation of ligase activity (GO:0051351)2.86824606
130mitotic spindle assembly checkpoint (GO:0007094)2.86575095
131mRNA catabolic process (GO:0006402)2.86558484
132regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.86459718
133pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.86378742
134cellular component biogenesis (GO:0044085)2.84361799
135pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.83497245
136signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.83305279
137signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.83305279
138signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.83305279
139intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.83056041

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.04151143
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.42551950
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.09229247
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.70919556
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.67994162
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.54193940
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.30460420
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.27414178
9GABP_17652178_ChIP-ChIP_JURKAT_Human3.26320732
10* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.11985969
11* ETS1_20019798_ChIP-Seq_JURKAT_Human3.09253416
12* CREB1_15753290_ChIP-ChIP_HEK293T_Human3.08387509
13* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.98672349
14MYC_19079543_ChIP-ChIP_MESCs_Mouse2.89032089
15MYC_19030024_ChIP-ChIP_MESCs_Mouse2.83067745
16XRN2_22483619_ChIP-Seq_HELA_Human2.51901098
17SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.49109917
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.44093021
19NELFA_20434984_ChIP-Seq_ESCs_Mouse2.38596421
20MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.36678317
21VDR_23849224_ChIP-Seq_CD4+_Human2.35854318
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.29998587
23NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.28862498
24* AR_21909140_ChIP-Seq_LNCAP_Human2.27187932
25DCP1A_22483619_ChIP-Seq_HELA_Human2.23204323
26E2F1_18555785_ChIP-Seq_MESCs_Mouse2.14363267
27ELF1_17652178_ChIP-ChIP_JURKAT_Human2.11672048
28GABP_19822575_ChIP-Seq_HepG2_Human2.06021267
29* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.05289123
30* FOXP3_21729870_ChIP-Seq_TREG_Human2.03523657
31* TTF2_22483619_ChIP-Seq_HELA_Human2.00376655
32E2F1_21310950_ChIP-Seq_MCF-7_Human1.96914300
33PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.88438433
34MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.88365090
35SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.83533961
36THAP11_20581084_ChIP-Seq_MESCs_Mouse1.82453513
37MYCN_18555785_ChIP-Seq_MESCs_Mouse1.82118642
38CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.74840740
39FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.73717477
40E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.73371207
41ELK1_19687146_ChIP-ChIP_HELA_Human1.69348268
42ZFX_18555785_ChIP-Seq_MESCs_Mouse1.68430625
43* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.67132291
44SRF_21415370_ChIP-Seq_HL-1_Mouse1.63716991
45POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.63577650
46YY1_21170310_ChIP-Seq_MESCs_Mouse1.58481761
47HOXB4_20404135_ChIP-ChIP_EML_Mouse1.57581922
48CIITA_25753668_ChIP-Seq_RAJI_Human1.51372849
49ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.51327693
50YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.45738939
51* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.42379305
52MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.39444140
53KDM5A_27292631_Chip-Seq_BREAST_Human1.39405781
54NANOG_18555785_ChIP-Seq_MESCs_Mouse1.36006107
55ERG_20887958_ChIP-Seq_HPC-7_Mouse1.33108313
56FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.32856192
57SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.30758190
58E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.26530858
59KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.25538305
60PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.22400528
61RBPJ_22232070_ChIP-Seq_NCS_Mouse1.21377252
62MYC_22102868_ChIP-Seq_BL_Human1.21069501
63DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.19396785
64KLF4_18555785_ChIP-Seq_MESCs_Mouse1.18564400
65ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.16442589
66TP63_19390658_ChIP-ChIP_HaCaT_Human1.13044157
67PADI4_21655091_ChIP-ChIP_MCF-7_Human1.12847804
68HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.12210495
69PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.11626528
70CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.11069855
71* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.10457411
72KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.08267136
73MYC_18940864_ChIP-ChIP_HL60_Human1.06095469
74TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.04175596
75* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.03172194
76ELK1_22589737_ChIP-Seq_MCF10A_Human1.01674872
77* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.01523196
78BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.01343974
79STAT3_1855785_ChIP-Seq_MESCs_Mouse1.00910272
80ZNF263_19887448_ChIP-Seq_K562_Human1.00187157
81EGR1_19374776_ChIP-ChIP_THP-1_Human0.99783878
82TFEB_21752829_ChIP-Seq_HELA_Human0.99088771
83* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.95943407
84SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.95819553
85VDR_21846776_ChIP-Seq_THP-1_Human0.94360186
86SOX2_18555785_ChIP-Seq_MESCs_Mouse0.93774793
87CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.91941380
88GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.90446684
89CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.88538034
90HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.88101760
91TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.86963538
92SPI1_23547873_ChIP-Seq_NB4_Human0.85248108
93CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.84537419
94NOTCH1_21737748_ChIP-Seq_TLL_Human0.83790366
95* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.83322346
96CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.82659643
97ESR1_15608294_ChIP-ChIP_MCF-7_Human0.82028790
98KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.80657029
99NANOG_21062744_ChIP-ChIP_HESCs_Human0.78890645
100TBX5_21415370_ChIP-Seq_HL-1_Mouse0.78023686
101TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.77263180
102GATA1_22383799_ChIP-Seq_G1ME_Mouse0.76110793
103DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.75906050
104SOX17_20123909_ChIP-Seq_XEN_Mouse0.75263253
105* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.73954322
106PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.71833242
107CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.71621520
108CHD1_26751641_Chip-Seq_LNCaP_Human0.71446765
109TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.70888509
110FOXP1_21924763_ChIP-Seq_HESCs_Human0.67171570

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.54301800
2MP0010094_abnormal_chromosome_stability4.47712056
3MP0004957_abnormal_blastocyst_morpholog4.31679089
4MP0003111_abnormal_nucleus_morphology4.26307841
5MP0003077_abnormal_cell_cycle3.84284063
6MP0008057_abnormal_DNA_replication3.28802893
7MP0008058_abnormal_DNA_repair3.07410702
8MP0008007_abnormal_cellular_replicative3.00212995
9MP0008932_abnormal_embryonic_tissue2.91144996
10MP0002396_abnormal_hematopoietic_system2.41713877
11MP0003718_maternal_effect2.11049182
12MP0001730_embryonic_growth_arrest2.07410963
13MP0003123_paternal_imprinting2.01847884
14MP0003786_premature_aging1.98621998
15MP0000350_abnormal_cell_proliferation1.97857525
16MP0010030_abnormal_orbit_morphology1.93541050
17MP0003656_abnormal_erythrocyte_physiolo1.90460150
18MP0004147_increased_porphyrin_level1.87926590
19MP0006054_spinal_hemorrhage1.80948904
20MP0003806_abnormal_nucleotide_metabolis1.78382294
21MP0000490_abnormal_crypts_of1.77329401
22MP0008877_abnormal_DNA_methylation1.65489422
23MP0010352_gastrointestinal_tract_polyps1.65037270
24MP0001697_abnormal_embryo_size1.59054843
25MP0002877_abnormal_melanocyte_morpholog1.54265031
26MP0009333_abnormal_splenocyte_physiolog1.51177187
27MP0002132_abnormal_respiratory_system1.49020804
28MP0001672_abnormal_embryogenesis/_devel1.48154548
29MP0005380_embryogenesis_phenotype1.48154548
30MP0009379_abnormal_foot_pigmentation1.48087562
31MP0010307_abnormal_tumor_latency1.47579886
32MP0003315_abnormal_perineum_morphology1.43690969
33MP0002080_prenatal_lethality1.43627998
34MP0000313_abnormal_cell_death1.41128271
35MP0005397_hematopoietic_system_phenotyp1.40999434
36MP0001545_abnormal_hematopoietic_system1.40999434
37MP0003186_abnormal_redox_activity1.40754212
38MP0002019_abnormal_tumor_incidence1.39140247
39MP0003984_embryonic_growth_retardation1.36026925
40MP0002210_abnormal_sex_determination1.34737093
41MP0002088_abnormal_embryonic_growth/wei1.32222257
42MP0002085_abnormal_embryonic_tissue1.31912847
43MP0001293_anophthalmia1.29282197
44MP0005451_abnormal_body_composition1.28215713
45MP0003567_abnormal_fetal_cardiomyocyte1.27099556
46MP0004808_abnormal_hematopoietic_stem1.25251940
47MP0003011_delayed_dark_adaptation1.22334543
48MP0005075_abnormal_melanosome_morpholog1.21113725
49MP0001145_abnormal_male_reproductive1.17909127
50MP0000537_abnormal_urethra_morphology1.17273282
51MP0001929_abnormal_gametogenesis1.15232332
52MP0002102_abnormal_ear_morphology1.15184587
53MP0004233_abnormal_muscle_weight1.14060984
54MP0001346_abnormal_lacrimal_gland1.13799944
55MP0002084_abnormal_developmental_patter1.12673214
56MP0005501_abnormal_skin_physiology1.08309134
57MP0002086_abnormal_extraembryonic_tissu1.07763133
58MP0000653_abnormal_sex_gland1.07400116
59MP0008789_abnormal_olfactory_epithelium1.06512610
60MP0008995_early_reproductive_senescence1.03304856
61MP0004197_abnormal_fetal_growth/weight/1.03141894
62MP0003763_abnormal_thymus_physiology1.01400333
63MP0002160_abnormal_reproductive_system1.00836380
64MP0003937_abnormal_limbs/digits/tail_de1.00563659
65MP0001119_abnormal_female_reproductive0.97904363
66MP0002163_abnormal_gland_morphology0.97521801
67MP0006036_abnormal_mitochondrial_physio0.94571594
68MP0009672_abnormal_birth_weight0.94456400
69MP0001529_abnormal_vocalization0.90851999
70MP0000049_abnormal_middle_ear0.89333960
71MP0009053_abnormal_anal_canal0.89247536
72MP0003221_abnormal_cardiomyocyte_apopto0.88549620
73MP0000358_abnormal_cell_content/0.87490308
74MP0004185_abnormal_adipocyte_glucose0.87288123
75MP0002282_abnormal_trachea_morphology0.85926742
76MP0005389_reproductive_system_phenotype0.85723462
77MP0001727_abnormal_embryo_implantation0.85261071
78MP0002111_abnormal_tail_morphology0.82835453
79MP0002006_tumorigenesis0.81685040
80MP0001661_extended_life_span0.81308933
81MP0001764_abnormal_homeostasis0.81089496
82MP0000703_abnormal_thymus_morphology0.79631706
83MP0002938_white_spotting0.79236649
84MP0002092_abnormal_eye_morphology0.77706145
85MP0003121_genomic_imprinting0.77173700
86MP0000372_irregular_coat_pigmentation0.76906685
87MP0004134_abnormal_chest_morphology0.76379800
88MP0002398_abnormal_bone_marrow0.75734934
89MP0000689_abnormal_spleen_morphology0.75306801
90MP0005621_abnormal_cell_physiology0.73904455
91MP0005499_abnormal_olfactory_system0.73264032
92MP0005394_taste/olfaction_phenotype0.73264032
93MP0009697_abnormal_copulation0.72577862
94MP0002722_abnormal_immune_system0.72114811
95MP0003938_abnormal_ear_development0.71772229
96MP0001881_abnormal_mammary_gland0.71757706
97MP0002166_altered_tumor_susceptibility0.71323805
98MP0003942_abnormal_urinary_system0.70715066
99MP0002009_preneoplasia0.69904957
100MP0009250_abnormal_appendicular_skeleto0.69372583
101MP0003941_abnormal_skin_development0.68579826
102MP0001542_abnormal_bone_strength0.68384241
103MP0008260_abnormal_autophagy0.68188288
104MP0002249_abnormal_larynx_morphology0.68177986
105MP0001915_intracranial_hemorrhage0.66787093
106MP0000566_synostosis0.66540588
107MP0006292_abnormal_olfactory_placode0.66240860
108MP0000858_altered_metastatic_potential0.65383481
109MP0002796_impaired_skin_barrier0.64943418
110MP0003698_abnormal_male_reproductive0.63915545
111MP0001853_heart_inflammation0.63802521
112MP0005395_other_phenotype0.62152048
113MP0002429_abnormal_blood_cell0.62133390
114MP0006035_abnormal_mitochondrial_morpho0.61009368
115MP0005384_cellular_phenotype0.60735797
116MP0005266_abnormal_metabolism0.60014457
117MP0000428_abnormal_craniofacial_morphol0.58828932
118MP0005023_abnormal_wound_healing0.57894411
119MP0002653_abnormal_ependyma_morphology0.57491049
120MP0005408_hypopigmentation0.57397549
121MP0005330_cardiomyopathy0.57343694
122MP0000627_abnormal_mammary_gland0.56902475
123MP0000477_abnormal_intestine_morphology0.55634554
124MP0002161_abnormal_fertility/fecundity0.55245489
125MP0003699_abnormal_female_reproductive0.54917650
126MP0001919_abnormal_reproductive_system0.54630425
127MP0001849_ear_inflammation0.54236613
128MP0003943_abnormal_hepatobiliary_system0.53756576
129MP0002932_abnormal_joint_morphology0.53244949
130MP0001286_abnormal_eye_development0.53243315
131MP0000716_abnormal_immune_system0.52292082
132MP0005076_abnormal_cell_differentiation0.51166584
133MP0009703_decreased_birth_body0.51142104
134MP0000678_abnormal_parathyroid_gland0.51118099

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.50539724
2Abnormal number of erythroid precursors (HP:0012131)5.37489660
3Reticulocytopenia (HP:0001896)5.10212985
4Birth length less than 3rd percentile (HP:0003561)4.75051231
5Microvesicular hepatic steatosis (HP:0001414)3.81399603
6Oral leukoplakia (HP:0002745)3.76572605
7Breast hypoplasia (HP:0003187)3.76218042
8Aplastic anemia (HP:0001915)3.61920561
9Abnormality of the heme biosynthetic pathway (HP:0010472)3.52911031
10Abnormal mitochondria in muscle tissue (HP:0008316)3.36171113
11Acute necrotizing encephalopathy (HP:0006965)3.33020515
12Macrocytic anemia (HP:0001972)3.28419644
13Irregular epiphyses (HP:0010582)3.26287485
14Rough bone trabeculation (HP:0100670)3.20153176
15Pallor (HP:0000980)3.19707754
16Patellar aplasia (HP:0006443)3.13908800
17Acute encephalopathy (HP:0006846)3.08107783
18Reduced antithrombin III activity (HP:0001976)3.07998955
19Carpal bone hypoplasia (HP:0001498)3.07195984
20Aplasia/Hypoplasia of the patella (HP:0006498)3.05589919
21Progressive muscle weakness (HP:0003323)3.03027874
22Cerebral hypomyelination (HP:0006808)3.02097880
2311 pairs of ribs (HP:0000878)2.99819699
24Increased CSF lactate (HP:0002490)2.97926898
25Aplasia/Hypoplasia of the sacrum (HP:0008517)2.96232225
26Abnormality of the anterior horn cell (HP:0006802)2.96163434
27Degeneration of anterior horn cells (HP:0002398)2.96163434
28Chromsome breakage (HP:0040012)2.89580170
29Mitochondrial inheritance (HP:0001427)2.84925575
30Meckel diverticulum (HP:0002245)2.84470591
31Cerebral edema (HP:0002181)2.78056956
32Abnormality of the preputium (HP:0100587)2.75022848
33Colon cancer (HP:0003003)2.73436952
34Abnormality of the ileum (HP:0001549)2.73023024
35Microretrognathia (HP:0000308)2.70920973
36Abnormality of chromosome stability (HP:0003220)2.70869221
37Chromosomal breakage induced by crosslinking agents (HP:0003221)2.69957385
38Selective tooth agenesis (HP:0001592)2.65903540
39Increased intramyocellular lipid droplets (HP:0012240)2.64215882
40B lymphocytopenia (HP:0010976)2.61515374
41Increased hepatocellular lipid droplets (HP:0006565)2.59802149
42Progressive macrocephaly (HP:0004481)2.57930953
43Multiple enchondromatosis (HP:0005701)2.55932574
44Small intestinal stenosis (HP:0012848)2.53173794
45Duodenal stenosis (HP:0100867)2.53173794
46Abnormal glycosylation (HP:0012345)2.52687634
47Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.52687634
48Abnormal protein N-linked glycosylation (HP:0012347)2.52687634
49Abnormal protein glycosylation (HP:0012346)2.52687634
50Hypoplasia of the capital femoral epiphysis (HP:0003090)2.51546972
51Abnormal lung lobation (HP:0002101)2.48687527
52Secondary amenorrhea (HP:0000869)2.48251077
53Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.47187672
54Absent epiphyses (HP:0010577)2.47187672
55Absent thumb (HP:0009777)2.45269216
56Lipid accumulation in hepatocytes (HP:0006561)2.44190684
57Abnormality of glycolysis (HP:0004366)2.42452910
58Aplasia/Hypoplasia of the uvula (HP:0010293)2.41480238
59Exercise intolerance (HP:0003546)2.40175934
60Glossoptosis (HP:0000162)2.36468177
61Lactic acidosis (HP:0003128)2.36203605
62Increased serum pyruvate (HP:0003542)2.35612380
63Myelodysplasia (HP:0002863)2.35089463
64Impulsivity (HP:0100710)2.31298697
65Rhabdomyosarcoma (HP:0002859)2.30075713
66Thrombocytosis (HP:0001894)2.29793318
67Increased muscle lipid content (HP:0009058)2.25706830
68Premature ovarian failure (HP:0008209)2.23876814
69Abnormal trabecular bone morphology (HP:0100671)2.22769608
70Bone marrow hypocellularity (HP:0005528)2.20715898
71Pancytopenia (HP:0001876)2.20071464
72Neoplasm of the pancreas (HP:0002894)2.18651261
73Trismus (HP:0000211)2.14967296
74Combined immunodeficiency (HP:0005387)2.14686713
75Abnormality of the carotid arteries (HP:0005344)2.14077865
76Atresia of the external auditory canal (HP:0000413)2.13615244
77Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.13167551
78Decreased activity of mitochondrial respiratory chain (HP:0008972)2.13167551
79Abnormality of reticulocytes (HP:0004312)2.11557309
80Ragged-red muscle fibers (HP:0003200)2.11036621
81Absent radius (HP:0003974)2.10975433
82Sloping forehead (HP:0000340)2.10381161
83Premature graying of hair (HP:0002216)2.10170397
84Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.09026118
85Abnormal spermatogenesis (HP:0008669)2.07522017
86Triphalangeal thumb (HP:0001199)2.06524713
87Horseshoe kidney (HP:0000085)2.06335272
88Abnormal umbilical cord blood vessels (HP:0011403)2.05580946
89Single umbilical artery (HP:0001195)2.05580946
90Abnormality of the fetal cardiovascular system (HP:0010948)2.05580946
91Abnormality of B cell number (HP:0010975)2.04459825
92Duplicated collecting system (HP:0000081)2.03509843
93Ectopic kidney (HP:0000086)2.01862196
94Progressive external ophthalmoplegia (HP:0000590)2.01522037
95Sparse eyelashes (HP:0000653)2.01072278
96Poor head control (HP:0002421)2.00430248
97Septate vagina (HP:0001153)1.98358307
98Medulloblastoma (HP:0002885)1.95981639
99Respiratory difficulties (HP:0002880)1.93988433
100Abnormal gallbladder physiology (HP:0012438)1.93758550
101Cholecystitis (HP:0001082)1.93758550
102Absent forearm bone (HP:0003953)1.93516308
103Aplasia involving forearm bones (HP:0009822)1.93516308
104Abnormality of the renal collecting system (HP:0004742)1.93189900
105Abnormality of methionine metabolism (HP:0010901)1.93107318
106Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.92347451
107Severe combined immunodeficiency (HP:0004430)1.92034238
108Abnormality of the duodenum (HP:0002246)1.91533690
109Increased serum lactate (HP:0002151)1.90876338
110Hepatocellular necrosis (HP:0001404)1.87704987
111Abnormality of the umbilical cord (HP:0010881)1.85872813
112Respiratory failure (HP:0002878)1.85251502
113Panhypogammaglobulinemia (HP:0003139)1.83808928
114Aplasia/Hypoplasia of the thymus (HP:0010515)1.82343463
115Renal Fanconi syndrome (HP:0001994)1.82275436
116Cutaneous melanoma (HP:0012056)1.82265622
117Ureteral duplication (HP:0000073)1.81218622
118Clubbing of toes (HP:0100760)1.80897293
119Hypoplasia of the radius (HP:0002984)1.80538151
120Slender long bone (HP:0003100)1.79956901
121Abnormal hemoglobin (HP:0011902)1.78565787
122Genu varum (HP:0002970)1.77550880
123Small epiphyses (HP:0010585)1.77029146
124Leukodystrophy (HP:0002415)1.75415534
125Type I transferrin isoform profile (HP:0003642)1.74302898
126Postnatal microcephaly (HP:0005484)1.73946345
127Abnormality of the calcaneus (HP:0008364)1.73382965
128Tracheoesophageal fistula (HP:0002575)1.72984771
129Proximal placement of thumb (HP:0009623)1.72869044
130Choanal atresia (HP:0000453)1.72344060
131Abnormality of DNA repair (HP:0003254)1.71600373
132Muscle fiber atrophy (HP:0100295)1.71224466
133Cleft eyelid (HP:0000625)1.70970341
134Hepatic necrosis (HP:0002605)1.70829912
135Cafe-au-lait spot (HP:0000957)1.70747376
136Nephroblastoma (Wilms tumor) (HP:0002667)1.70524596
137Pulmonary fibrosis (HP:0002206)1.69544402
138Short middle phalanx of the 5th finger (HP:0004220)1.68654291
139Aplasia/Hypoplasia of the sternum (HP:0006714)1.65176539
140Calcaneovalgus deformity (HP:0001848)1.64518105
141Exertional dyspnea (HP:0002875)1.64238261
142Depressed nasal ridge (HP:0000457)1.61260386
143Short thumb (HP:0009778)1.61225899
144Missing ribs (HP:0000921)1.60313162
145Cellular immunodeficiency (HP:0005374)1.60165887
146Increased nuchal translucency (HP:0010880)1.60154011
147Embryonal renal neoplasm (HP:0011794)1.60141555
148Abnormality of pyrimidine metabolism (HP:0004353)1.59700317
149Squamous cell carcinoma (HP:0002860)1.59672277
150Neoplasm of striated muscle (HP:0009728)1.59533057

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.03544080
2CDC74.05316420
3WEE14.01033271
4VRK23.85020198
5EIF2AK13.39811875
6NME23.09104403
7ACVR1B2.96091190
8STK162.58104409
9NEK22.54710826
10PLK42.42736255
11SRPK12.39559298
12MKNK12.19053016
13BRSK22.08904917
14VRK12.07769492
15TTK1.95703701
16DYRK31.91205990
17NEK11.87903023
18PLK11.85775015
19EIF2AK31.79045385
20TLK11.78976708
21CCNB11.77943524
22TESK21.75653401
23NUAK11.73484038
24PIM21.67053745
25AURKB1.65360765
26LATS11.64492877
27RPS6KA41.64251343
28PRPF4B1.52985806
29BRSK11.47865847
30TSSK61.42961625
31SMG11.41056338
32ATR1.40193305
33CDK71.39294181
34PLK31.38199276
35SCYL21.36040365
36MKNK21.21949269
37AURKA1.20110278
38TGFBR11.19531647
39RPS6KB21.18203391
40CHEK21.16134489
41TAF11.15442020
42CDK81.15414351
43MAP3K81.14322665
44PASK1.08953312
45CDK41.05873497
46STK101.02948570
47TRIM280.99885051
48PDK20.98607997
49IRAK30.95630117
50TESK10.95559378
51CDK120.93845694
52PBK0.93620668
53CHEK10.91991983
54ALK0.87987325
55BRAF0.80436106
56LRRK20.79840265
57STK30.79318071
58MELK0.74902474
59PAK40.73569200
60CDK190.73221094
61MAP3K110.71895832
62MAP3K100.71331187
63DYRK20.70903114
64CSNK2A10.70173377
65ABL20.69179252
66DAPK10.68495855
67EEF2K0.64846119
68ZAK0.64827727
69PIM10.62839251
70RAF10.62219266
71PAK10.61491326
72CDK20.61319924
73EIF2AK20.59668423
74NME10.59489109
75BCKDK0.58936364
76ATM0.58539882
77STK40.57677468
78CSNK2A20.57531066
79MST1R0.57259472
80NEK90.55458281
81KDR0.53417724
82RPS6KA50.53103612
83ILK0.51793917
84ARAF0.50754831
85CDK10.50706016
86CLK10.45856064
87ERBB40.44129260
88LIMK10.43642309
89PNCK0.43183674
90CDK90.42053919
91IRAK40.41098598
92MAP3K120.41006585
93CDK60.40623451
94CDK140.39807373
95PRKDC0.33928194
96EPHA20.33286424
97CSNK1G10.32937542
98MAPKAPK30.32872686
99STK38L0.32319458
100MAP2K30.32103598
101CSNK1E0.32048521
102CDK180.30740590
103CDK150.30361484
104CDK30.29035103
105CSNK1A1L0.27912559
106MAP3K30.25967123
107SIK30.25649985
108TAOK20.25304655
109PRKCI0.24982346
110MST40.23665632
111TEC0.23532067
112MAPKAPK50.23341754
113MAPKAPK20.23084023
114BTK0.22988576
115CSNK1G30.22739880
116PDK30.22309410
117PDK40.22309410
118AKT20.22258720
119ERBB30.21293158
120PAK20.20805817
121RPS6KA60.20618105
122CSNK1G20.19656086
123LATS20.19608766
124MAP3K50.19504677
125EPHB20.19348333
126CDK11A0.18553611

Predicted pathways (KEGG)

RankGene SetZ-score
1* DNA replication_Homo sapiens_hsa030305.02538463
2Ribosome_Homo sapiens_hsa030104.17396135
3Mismatch repair_Homo sapiens_hsa034303.95751474
4Proteasome_Homo sapiens_hsa030503.60007328
5Spliceosome_Homo sapiens_hsa030403.28029283
6RNA polymerase_Homo sapiens_hsa030203.20827015
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.17233795
8Homologous recombination_Homo sapiens_hsa034402.95608715
9* Base excision repair_Homo sapiens_hsa034102.95452548
10RNA transport_Homo sapiens_hsa030132.83138586
11* Nucleotide excision repair_Homo sapiens_hsa034202.77481372
12Cell cycle_Homo sapiens_hsa041102.70725223
13* Pyrimidine metabolism_Homo sapiens_hsa002402.62843367
14One carbon pool by folate_Homo sapiens_hsa006702.39633707
15Fanconi anemia pathway_Homo sapiens_hsa034602.07210278
16Basal transcription factors_Homo sapiens_hsa030221.98101143
17RNA degradation_Homo sapiens_hsa030181.76161076
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.74302391
19Non-homologous end-joining_Homo sapiens_hsa034501.73402157
20p53 signaling pathway_Homo sapiens_hsa041151.51885061
21Vitamin B6 metabolism_Homo sapiens_hsa007501.42500430
22mRNA surveillance pathway_Homo sapiens_hsa030151.39353455
23* Purine metabolism_Homo sapiens_hsa002301.38618891
24Folate biosynthesis_Homo sapiens_hsa007901.28615158
25Fatty acid elongation_Homo sapiens_hsa000621.28020690
26Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.25618321
27Protein export_Homo sapiens_hsa030601.25134899
28Sulfur relay system_Homo sapiens_hsa041221.14827030
29Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.09064780
30Epstein-Barr virus infection_Homo sapiens_hsa051691.07165844
31Parkinsons disease_Homo sapiens_hsa050121.05775595
32Huntingtons disease_Homo sapiens_hsa050161.03507550
33Cysteine and methionine metabolism_Homo sapiens_hsa002700.96040090
34Systemic lupus erythematosus_Homo sapiens_hsa053220.93449925
35Drug metabolism - other enzymes_Homo sapiens_hsa009830.93330359
36Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.92051600
37Glutathione metabolism_Homo sapiens_hsa004800.91367178
38Pentose phosphate pathway_Homo sapiens_hsa000300.87378525
39Cyanoamino acid metabolism_Homo sapiens_hsa004600.84770095
40Primary immunodeficiency_Homo sapiens_hsa053400.83193002
41Oocyte meiosis_Homo sapiens_hsa041140.82510710
42Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.81100363
43Oxidative phosphorylation_Homo sapiens_hsa001900.75831465
44Herpes simplex infection_Homo sapiens_hsa051680.75377536
45Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.72445668
46Viral carcinogenesis_Homo sapiens_hsa052030.72311791
47Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.72134847
48Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.71649273
49Propanoate metabolism_Homo sapiens_hsa006400.71485000
50Selenocompound metabolism_Homo sapiens_hsa004500.67896686
51Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.65548698
52Biosynthesis of amino acids_Homo sapiens_hsa012300.63072028
53Thyroid cancer_Homo sapiens_hsa052160.59220558
54* HTLV-I infection_Homo sapiens_hsa051660.56655351
55N-Glycan biosynthesis_Homo sapiens_hsa005100.53858863
56Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.53753628
57Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.52492241
58Carbon metabolism_Homo sapiens_hsa012000.51494504
59Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.51113167
60Small cell lung cancer_Homo sapiens_hsa052220.50366778
61Legionellosis_Homo sapiens_hsa051340.49991592
62Antigen processing and presentation_Homo sapiens_hsa046120.48843585
63Arachidonic acid metabolism_Homo sapiens_hsa005900.47465727
64Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.47321549
65Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.46578745
66Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.44350450
67Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.43077311
68* Metabolic pathways_Homo sapiens_hsa011000.41000792
69Apoptosis_Homo sapiens_hsa042100.40431394
70Shigellosis_Homo sapiens_hsa051310.39786985
71MicroRNAs in cancer_Homo sapiens_hsa052060.36139597
72Bladder cancer_Homo sapiens_hsa052190.35356708
73Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.34852249
74Sulfur metabolism_Homo sapiens_hsa009200.34708004
75Basal cell carcinoma_Homo sapiens_hsa052170.32634121
76Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.30948109
77Alzheimers disease_Homo sapiens_hsa050100.30225317
78Hepatitis B_Homo sapiens_hsa051610.29650570
79Hippo signaling pathway_Homo sapiens_hsa043900.28574729
80Steroid biosynthesis_Homo sapiens_hsa001000.28056312
81TGF-beta signaling pathway_Homo sapiens_hsa043500.27442424
82Notch signaling pathway_Homo sapiens_hsa043300.26921237
832-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.25650802
84Fatty acid metabolism_Homo sapiens_hsa012120.25072033
85Lysine degradation_Homo sapiens_hsa003100.24940230
86Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.24649865
87Transcriptional misregulation in cancer_Homo sapiens_hsa052020.24605125
88Hedgehog signaling pathway_Homo sapiens_hsa043400.23045852
89Chronic myeloid leukemia_Homo sapiens_hsa052200.19760700
90Alcoholism_Homo sapiens_hsa050340.19751199
91Galactose metabolism_Homo sapiens_hsa000520.18104706
92Colorectal cancer_Homo sapiens_hsa052100.17668724
93Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.17535880
94Caffeine metabolism_Homo sapiens_hsa002320.16640146
95Pancreatic cancer_Homo sapiens_hsa052120.16069161
96Arginine and proline metabolism_Homo sapiens_hsa003300.15571262
97Linoleic acid metabolism_Homo sapiens_hsa005910.15546199
98Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.15253449
99SNARE interactions in vesicular transport_Homo sapiens_hsa041300.15020646
100Fructose and mannose metabolism_Homo sapiens_hsa000510.14847572
101Regulation of autophagy_Homo sapiens_hsa041400.14287890
102Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.13946741
103Non-small cell lung cancer_Homo sapiens_hsa052230.13890980
104Measles_Homo sapiens_hsa051620.13738528
105Central carbon metabolism in cancer_Homo sapiens_hsa052300.12969912
106Pyruvate metabolism_Homo sapiens_hsa006200.12752740
107Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.12288254
108Renin-angiotensin system_Homo sapiens_hsa046140.09830970
109Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.08981263
110Prostate cancer_Homo sapiens_hsa052150.08899007
111PI3K-Akt signaling pathway_Homo sapiens_hsa041510.08488583
112Pathways in cancer_Homo sapiens_hsa052000.08156261
113Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.07678304
114Pentose and glucuronate interconversions_Homo sapiens_hsa000400.06969167
115Cardiac muscle contraction_Homo sapiens_hsa042600.06909159
116Peroxisome_Homo sapiens_hsa041460.05755880
117Hematopoietic cell lineage_Homo sapiens_hsa046400.05111824
118alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.04504920
119Viral myocarditis_Homo sapiens_hsa054160.04283696
120Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.03806426

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