PNN

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic sister chromatid cohesion (GO:0007064)6.00395482
2negative regulation of mRNA splicing, via spliceosome (GO:0048025)4.88130788
3DNA unwinding involved in DNA replication (GO:0006268)4.61175609
4negative regulation of RNA splicing (GO:0033119)4.52135637
5nuclear pore complex assembly (GO:0051292)4.49065971
6pre-miRNA processing (GO:0031054)4.43338105
7mitotic chromosome condensation (GO:0007076)4.36348301
8negative regulation of mRNA processing (GO:0050686)4.35431494
9nuclear pore organization (GO:0006999)4.32436237
10protein localization to kinetochore (GO:0034501)4.20199811
11regulation of RNA export from nucleus (GO:0046831)4.13163960
12DNA strand elongation (GO:0022616)4.05214555
13maturation of SSU-rRNA (GO:0030490)4.03329443
14kinetochore organization (GO:0051383)4.02699470
15ribosomal small subunit biogenesis (GO:0042274)4.01048203
16viral transcription (GO:0019083)3.96330626
17negative regulation of mRNA metabolic process (GO:1903312)3.93832014
18translational termination (GO:0006415)3.92848653
19sister chromatid segregation (GO:0000819)3.91756989
20negative regulation of histone methylation (GO:0031061)3.88138163
21ribosomal small subunit assembly (GO:0000028)3.83371041
22mitotic sister chromatid segregation (GO:0000070)3.81797939
23chromatin remodeling at centromere (GO:0031055)3.81702920
24mRNA splice site selection (GO:0006376)3.81576916
25mitotic metaphase plate congression (GO:0007080)3.77647668
26telomere maintenance via semi-conservative replication (GO:0032201)3.77570486
27establishment of integrated proviral latency (GO:0075713)3.75994540
28protein localization to chromosome, centromeric region (GO:0071459)3.75202682
29formation of translation preinitiation complex (GO:0001731)3.72355734
30regulation of sister chromatid cohesion (GO:0007063)3.72244498
31histone H3-K4 trimethylation (GO:0080182)3.70142356
32CENP-A containing nucleosome assembly (GO:0034080)3.69208618
33regulation of DNA endoreduplication (GO:0032875)3.67696699
34ribosomal large subunit biogenesis (GO:0042273)3.66019563
35viral mRNA export from host cell nucleus (GO:0046784)3.64046690
36nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.62136857
37telomere maintenance via recombination (GO:0000722)3.62068946
38regulation of centriole replication (GO:0046599)3.61122796
39regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.59383596
40metaphase plate congression (GO:0051310)3.57146689
41mitotic recombination (GO:0006312)3.52339376
42RNA stabilization (GO:0043489)3.52079724
43mRNA stabilization (GO:0048255)3.52079724
44alternative mRNA splicing, via spliceosome (GO:0000380)3.50973876
45dosage compensation (GO:0007549)3.48339160
46DNA duplex unwinding (GO:0032508)3.47391436
47translational initiation (GO:0006413)3.45952304
48DNA geometric change (GO:0032392)3.44337261
49positive regulation of histone H3-K4 methylation (GO:0051571)3.44187563
50DNA ligation (GO:0006266)3.40401219
51positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)3.40055708
52histone H3-K4 methylation (GO:0051568)3.39602093
53glucocorticoid receptor signaling pathway (GO:0042921)3.38486176
54mitotic nuclear envelope disassembly (GO:0007077)3.38056553
55* mRNA splicing, via spliceosome (GO:0000398)3.37594231
56* RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)3.37594231
57regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.36985252
58regulation of spindle organization (GO:0090224)3.36124282
59* RNA splicing, via transesterification reactions (GO:0000375)3.35503695
60kinetochore assembly (GO:0051382)3.31673145
61regulation of histone H3-K9 methylation (GO:0051570)3.30930393
62ribosome assembly (GO:0042255)3.30673353
63pore complex assembly (GO:0046931)3.30480435
64peptidyl-lysine trimethylation (GO:0018023)3.29865317
65DNA replication checkpoint (GO:0000076)3.28340929
66positive regulation of chromosome segregation (GO:0051984)3.28091831
67histone exchange (GO:0043486)3.26718231
68ribonucleoprotein complex biogenesis (GO:0022613)3.26208096
69SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.24958835
70translational elongation (GO:0006414)3.24698507
71regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.24031953
72cotranslational protein targeting to membrane (GO:0006613)3.21058555
73positive regulation of RNA splicing (GO:0033120)3.20493672
74regulation of histone H3-K4 methylation (GO:0051569)3.19985020
75mRNA export from nucleus (GO:0006406)3.19881186
76DNA topological change (GO:0006265)3.19827590
77heterochromatin organization (GO:0070828)3.19337011
78protein targeting to ER (GO:0045047)3.17991285
79RNA export from nucleus (GO:0006405)3.17860508
80regulation of mitotic spindle organization (GO:0060236)3.16854515
81termination of RNA polymerase II transcription (GO:0006369)3.15572884
82chromatin assembly or disassembly (GO:0006333)3.15246389
83regulation of nucleobase-containing compound transport (GO:0032239)3.14735443
84ATP-dependent chromatin remodeling (GO:0043044)3.14019906
85positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.13832703
86positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.13832703
87positive regulation of mitotic sister chromatid separation (GO:1901970)3.13832703
88membrane disassembly (GO:0030397)3.12695427
89nuclear envelope disassembly (GO:0051081)3.12695427
90histone H2A acetylation (GO:0043968)3.12320398
91histone H3-K9 methylation (GO:0051567)3.09688938
92* RNA splicing (GO:0008380)3.09033225
93DNA conformation change (GO:0071103)3.07178159
94DNA replication initiation (GO:0006270)3.06978230
95negative regulation of DNA-dependent DNA replication (GO:2000104)3.06891960
96establishment of protein localization to endoplasmic reticulum (GO:0072599)3.05848645
97DNA replication-independent nucleosome organization (GO:0034724)3.05478228
98DNA replication-independent nucleosome assembly (GO:0006336)3.05478228
99sister chromatid cohesion (GO:0007062)3.05138350
100DNA replication-dependent nucleosome organization (GO:0034723)3.03708057
101DNA replication-dependent nucleosome assembly (GO:0006335)3.03708057
102protein-DNA complex disassembly (GO:0032986)3.02676878
103nucleosome disassembly (GO:0006337)3.02676878
104protein localization to chromosome (GO:0034502)3.02258149
105mRNA transport (GO:0051028)3.01830099
106positive regulation of gene expression, epigenetic (GO:0045815)3.01111421
107monoubiquitinated protein deubiquitination (GO:0035520)3.00665262
108regulation of centrosome cycle (GO:0046605)3.00233312
109positive regulation of cell cycle checkpoint (GO:1901978)3.00064273
110cellular protein complex disassembly (GO:0043624)2.99323981
111regulation of mRNA stability (GO:0043488)2.98996372
112positive regulation of histone methylation (GO:0031062)2.98719239
113centriole replication (GO:0007099)2.98707309
114translesion synthesis (GO:0019985)2.98351918
115regulation of mRNA splicing, via spliceosome (GO:0048024)2.98144144
116protein complex disassembly (GO:0043241)2.98127512
117establishment of chromosome localization (GO:0051303)2.98103251
118V(D)J recombination (GO:0033151)2.97555772
119viral life cycle (GO:0019058)2.97486408
120IMP biosynthetic process (GO:0006188)2.96468419
121meiotic chromosome segregation (GO:0045132)2.96091581
122ribonucleoprotein complex assembly (GO:0022618)2.95584581
123chromosome condensation (GO:0030261)2.94341690
124histone H2B ubiquitination (GO:0033523)2.94127260
125ribosome biogenesis (GO:0042254)2.92987336
126regulation of histone methylation (GO:0031060)2.92708697
127nucleotide-excision repair, DNA gap filling (GO:0006297)2.92155271
128spliceosomal tri-snRNP complex assembly (GO:0000244)2.91841894
129attachment of spindle microtubules to kinetochore (GO:0008608)2.89203339
130regulation of RNA splicing (GO:0043484)2.88775094
131regulation of DNA damage checkpoint (GO:2000001)2.87917675
132DNA strand elongation involved in DNA replication (GO:0006271)2.87284933
133nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.85967134
134histone lysine methylation (GO:0034968)2.85940057
135regulation of chromosome segregation (GO:0051983)2.83520986
136cytoplasmic mRNA processing body assembly (GO:0033962)2.82955746
137DNA packaging (GO:0006323)2.82880399
138RNA transport (GO:0050658)2.81531744
139establishment of RNA localization (GO:0051236)2.81531744
140nucleic acid transport (GO:0050657)2.81531744
141chromatin assembly (GO:0031497)2.81306877
142regulation of mRNA processing (GO:0050684)2.80750509
143histone H2A monoubiquitination (GO:0035518)2.80690988
144histone H3-K9 modification (GO:0061647)2.79875415
145regulation of RNA stability (GO:0043487)2.79551999

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human6.43486043
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.75460777
3FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.74392357
4* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.54202342
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.35328891
6MYC_22102868_ChIP-Seq_BL_Human3.29448596
7MYC_18555785_ChIP-Seq_MESCs_Mouse3.24423455
8* TP63_19390658_ChIP-ChIP_HaCaT_Human3.05761888
9CIITA_25753668_ChIP-Seq_RAJI_Human2.66571665
10* E2F1_21310950_ChIP-Seq_MCF-7_Human2.56594299
11SALL1_21062744_ChIP-ChIP_HESCs_Human2.53417779
12AR_21909140_ChIP-Seq_LNCAP_Human2.48838975
13MYC_19079543_ChIP-ChIP_MESCs_Mouse2.45116697
14YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.42537854
15* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.10776831
16RBPJ_22232070_ChIP-Seq_NCS_Mouse2.07601193
17JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.05943836
18EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.04802344
19XRN2_22483619_ChIP-Seq_HELA_Human2.03774887
20KDM5A_27292631_Chip-Seq_BREAST_Human2.02256408
21E2F7_22180533_ChIP-Seq_HELA_Human10.4556978
22MYCN_18555785_ChIP-Seq_MESCs_Mouse1.81644037
23HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.79982343
24EST1_17652178_ChIP-ChIP_JURKAT_Human1.77734636
25* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.76041233
26E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.75490244
27CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.72099715
28MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.68731127
29PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.68162114
30TTF2_22483619_ChIP-Seq_HELA_Human1.62918673
31HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.62324785
32MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.61429498
33* FOXP3_21729870_ChIP-Seq_TREG_Human1.60257296
34HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.55395553
35NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.54048302
36MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.53881545
37DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.53486223
38HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.52737029
39ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.51507138
40* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.50924096
41VDR_21846776_ChIP-Seq_THP-1_Human1.49640913
42* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.47107958
43* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.46073559
44PKCTHETA_26484144_Chip-Seq_BREAST_Human1.41278261
45* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.40397518
46* VDR_23849224_ChIP-Seq_CD4+_Human1.40200303
47ELK1_19687146_ChIP-ChIP_HELA_Human1.37451459
48DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.36605643
49CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.36538644
50ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.36487042
51FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.34455396
52* ETS1_20019798_ChIP-Seq_JURKAT_Human1.34114644
53MYC_18940864_ChIP-ChIP_HL60_Human1.31165370
54KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.30381660
55KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.30381660
56KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.30381660
57TCF7_22412390_ChIP-Seq_EML_Mouse1.28912890
58* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.28728533
59* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.28055834
60NANOG_21062744_ChIP-ChIP_HESCs_Human1.25275701
61POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.24925357
62CREB1_15753290_ChIP-ChIP_HEK293T_Human1.24600626
63KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.24081732
64STAT6_21828071_ChIP-Seq_BEAS2B_Human1.23207544
65GABP_19822575_ChIP-Seq_HepG2_Human1.22996499
66THAP11_20581084_ChIP-Seq_MESCs_Mouse1.20392904
67PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.18446467
68CHD1_26751641_Chip-Seq_LNCaP_Human1.18043456
69SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.16730414
70CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.16548120
71PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.15503318
72* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.15447813
73SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.14553642
74ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.11618980
75* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.11222632
76* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.10508332
77UTX_26944678_Chip-Seq_JUKART_Human1.09659605
78NANOG_18555785_ChIP-Seq_MESCs_Mouse1.08462964
79TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.07800733
80YY1_21170310_ChIP-Seq_MESCs_Mouse1.07261912
81KDM2B_26808549_Chip-Seq_DND41_Human1.05383674
82SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.04411470
83FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.02881913
84KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.02367708
85EWS_26573619_Chip-Seq_HEK293_Human1.01889035
86SOX2_18555785_ChIP-Seq_MESCs_Mouse1.01604618
87* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.00242768
88CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.00183296
89BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.97841652
90CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.97779345
91DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.97279673
92SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.96841244
93DCP1A_22483619_ChIP-Seq_HELA_Human0.96431704
94KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.94906022
95ESR1_15608294_ChIP-ChIP_MCF-7_Human0.94335415
96FUS_26573619_Chip-Seq_HEK293_Human0.93374387
97* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.93213059
98ERG_20887958_ChIP-Seq_HPC-7_Mouse0.93205390
99POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.92391504
100* MYB_26560356_Chip-Seq_TH1_Human0.90965516
101RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.89864657
102SRF_21415370_ChIP-Seq_HL-1_Mouse0.89531575
103KLF4_18555785_ChIP-Seq_MESCs_Mouse0.86442462
104NANOG_16153702_ChIP-ChIP_HESCs_Human0.86031872
105SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.83308408
106ELF1_17652178_ChIP-ChIP_JURKAT_Human0.82726701
107IRF1_19129219_ChIP-ChIP_H3396_Human0.80895844
108* HOXB4_20404135_ChIP-ChIP_EML_Mouse0.80090182
109STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.79890889
110CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.78883564
111PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.77750076
112CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.76753152
113* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.76182427
114GABP_17652178_ChIP-ChIP_JURKAT_Human0.75014037
115KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.74791105
116KDM2B_26808549_Chip-Seq_JURKAT_Human0.74782840
117TFEB_21752829_ChIP-Seq_HELA_Human0.74574620
118HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.74529098
119SOX2_16153702_ChIP-ChIP_HESCs_Human0.74328818
120FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.74321077
121ZFP281_18757296_ChIP-ChIP_E14_Mouse0.73617382
122NOTCH1_21737748_ChIP-Seq_TLL_Human0.73386766
123SOX17_20123909_ChIP-Seq_XEN_Mouse0.73168702
124* NCOR1_26117541_ChIP-Seq_K562_Human0.72984222

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability3.67605624
2MP0003111_abnormal_nucleus_morphology3.61170837
3MP0003693_abnormal_embryo_hatching3.47131792
4MP0008057_abnormal_DNA_replication3.24952591
5MP0003077_abnormal_cell_cycle3.22024847
6MP0004957_abnormal_blastocyst_morpholog3.10319426
7MP0003121_genomic_imprinting2.72382302
8MP0008877_abnormal_DNA_methylation2.71524198
9MP0006292_abnormal_olfactory_placode2.63572633
10MP0003123_paternal_imprinting2.60480723
11MP0003787_abnormal_imprinting2.48084730
12MP0002396_abnormal_hematopoietic_system2.39711131
13MP0001730_embryonic_growth_arrest2.26969061
14MP0008058_abnormal_DNA_repair2.22819069
15MP0000350_abnormal_cell_proliferation2.12698147
16MP0008007_abnormal_cellular_replicative2.00892427
17MP0008995_early_reproductive_senescence2.00311003
18MP0005076_abnormal_cell_differentiation1.93610714
19* MP0002084_abnormal_developmental_patter1.92350355
20* MP0001672_abnormal_embryogenesis/_devel1.85955188
21* MP0005380_embryogenesis_phenotype1.85955188
22MP0002085_abnormal_embryonic_tissue1.82770388
23MP0003890_abnormal_embryonic-extraembry1.82189307
24MP0000569_abnormal_digit_pigmentation1.78521238
25* MP0003984_embryonic_growth_retardation1.76460444
26MP0001697_abnormal_embryo_size1.76238351
27* MP0002088_abnormal_embryonic_growth/wei1.73079302
28MP0004197_abnormal_fetal_growth/weight/1.72049939
29MP0010030_abnormal_orbit_morphology1.71393194
30MP0008932_abnormal_embryonic_tissue1.65328549
31MP0000428_abnormal_craniofacial_morphol1.64748415
32MP0004808_abnormal_hematopoietic_stem1.62623582
33MP0001293_anophthalmia1.61223348
34MP0009379_abnormal_foot_pigmentation1.52266210
35MP0010352_gastrointestinal_tract_polyps1.51242721
36MP0002086_abnormal_extraembryonic_tissu1.51178478
37MP0003122_maternal_imprinting1.50259083
38MP0003567_abnormal_fetal_cardiomyocyte1.49394013
39* MP0002080_prenatal_lethality1.46320915
40MP0009672_abnormal_birth_weight1.45509374
41MP0001849_ear_inflammation1.40678960
42MP0009053_abnormal_anal_canal1.39657968
43MP0000537_abnormal_urethra_morphology1.39392693
44MP0009697_abnormal_copulation1.39015252
45MP0009703_decreased_birth_body1.36771683
46MP0003937_abnormal_limbs/digits/tail_de1.33429536
47MP0003935_abnormal_craniofacial_develop1.29019331
48MP0003718_maternal_effect1.28899198
49MP0003136_yellow_coat_color1.28266998
50MP0000703_abnormal_thymus_morphology1.27006789
51MP0003119_abnormal_digestive_system1.23520154
52MP0003943_abnormal_hepatobiliary_system1.21831797
53MP0002009_preneoplasia1.20422964
54MP0003385_abnormal_body_wall1.19737194
55MP0010307_abnormal_tumor_latency1.18660028
56MP0004264_abnormal_extraembryonic_tissu1.17490284
57MP0003861_abnormal_nervous_system1.16856620
58MP0001286_abnormal_eye_development1.15960923
59MP0006072_abnormal_retinal_apoptosis1.15505985
60MP0003115_abnormal_respiratory_system1.13541498
61MP0000313_abnormal_cell_death1.10744587
62MP0000432_abnormal_head_morphology1.10654084
63MP0003786_premature_aging1.06603350
64MP0000733_abnormal_muscle_development1.05185383
65MP0002160_abnormal_reproductive_system1.04710011
66MP0001188_hyperpigmentation1.02491275
67MP0003705_abnormal_hypodermis_morpholog1.02296856
68MP0002092_abnormal_eye_morphology1.02153915
69* MP0002925_abnormal_cardiovascular_devel1.00682407
70* MP0002697_abnormal_eye_size1.00330318
71MP0003763_abnormal_thymus_physiology0.99035174
72MP0005187_abnormal_penis_morphology0.98929117
73MP0002210_abnormal_sex_determination0.98135671
74MP0001929_abnormal_gametogenesis0.97955164
75MP0003938_abnormal_ear_development0.97508090
76MP0002653_abnormal_ependyma_morphology0.96805604
77MP0002116_abnormal_craniofacial_bone0.91622080
78MP0002938_white_spotting0.89740999
79* MP0003755_abnormal_palate_morphology0.89303467
80MP0009278_abnormal_bone_marrow0.88558565
81MP0004233_abnormal_muscle_weight0.88314753
82MP0001346_abnormal_lacrimal_gland0.88235242
83MP0008789_abnormal_olfactory_epithelium0.88003451
84MP0003942_abnormal_urinary_system0.87865853
85MP0000566_synostosis0.87361447
86MP0002019_abnormal_tumor_incidence0.84909202
87MP0002249_abnormal_larynx_morphology0.83743071
88MP0002932_abnormal_joint_morphology0.81802780
89MP0004185_abnormal_adipocyte_glucose0.80848905
90* MP0002114_abnormal_axial_skeleton0.80650846
91MP0005257_abnormal_intraocular_pressure0.80640276
92MP0001145_abnormal_male_reproductive0.79582581
93* MP0000266_abnormal_heart_morphology0.79149060
94* MP0002081_perinatal_lethality0.78485498
95MP0003699_abnormal_female_reproductive0.78325471
96MP0004742_abnormal_vestibular_system0.77634169
97MP0003941_abnormal_skin_development0.77011285
98MP0008770_decreased_survivor_rate0.76365982
99MP0005391_vision/eye_phenotype0.76090904
100MP0002233_abnormal_nose_morphology0.75818109
101MP0003698_abnormal_male_reproductive0.75343583
102MP0000383_abnormal_hair_follicle0.75306463
103MP0000631_abnormal_neuroendocrine_gland0.74221711
104MP0002398_abnormal_bone_marrow0.74082772
105MP0002111_abnormal_tail_morphology0.73955336
106MP0005220_abnormal_exocrine_pancreas0.73872853
107MP0008961_abnormal_basal_metabolism0.73816957
108MP0000049_abnormal_middle_ear0.73584805
109MP0003283_abnormal_digestive_organ0.73243069
110MP0004133_heterotaxia0.73178795
111MP0005499_abnormal_olfactory_system0.73173582
112MP0005394_taste/olfaction_phenotype0.73173582
113MP0005408_hypopigmentation0.72156810
114MP0000653_abnormal_sex_gland0.72110793
115MP0003315_abnormal_perineum_morphology0.70614051
116MP0001915_intracranial_hemorrhage0.70539565
117MP0001119_abnormal_female_reproductive0.70405558
118MP0010630_abnormal_cardiac_muscle0.69760634
119MP0002089_abnormal_postnatal_growth/wei0.69109969
120MP0001299_abnormal_eye_distance/0.68428529
121MP0002161_abnormal_fertility/fecundity0.67710596
122* MP0001784_abnormal_fluid_regulation0.66972905
123MP0001529_abnormal_vocalization0.66277545
124MP0000490_abnormal_crypts_of0.65308461
125MP0002132_abnormal_respiratory_system0.64211984

Predicted human phenotypes

RankGene SetZ-score
1Volvulus (HP:0002580)4.76024215
2Abnormality of the fingertips (HP:0001211)3.97283871
3Reticulocytopenia (HP:0001896)3.76669141
4Nephroblastoma (Wilms tumor) (HP:0002667)3.42339244
5Increased nuchal translucency (HP:0010880)3.35506668
6Long eyelashes (HP:0000527)3.34787381
7Abnormality of cells of the erythroid lineage (HP:0012130)3.17422625
8Embryonal renal neoplasm (HP:0011794)3.15025506
9Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.98156441
10Short 4th metacarpal (HP:0010044)2.98156441
11Abnormal number of incisors (HP:0011064)2.95853824
12Ependymoma (HP:0002888)2.89719164
13Macrocytic anemia (HP:0001972)2.87080974
14Proximal placement of thumb (HP:0009623)2.82215236
15Medulloblastoma (HP:0002885)2.82196498
16Ectopic kidney (HP:0000086)2.79775500
17Chromsome breakage (HP:0040012)2.71972692
18Abnormality of cochlea (HP:0000375)2.70612541
19Deviation of the thumb (HP:0009603)2.67119266
20Hepatoblastoma (HP:0002884)2.65262788
21Prominent nose (HP:0000448)2.59796775
22Supernumerary ribs (HP:0005815)2.59398776
23Abnormality of the labia minora (HP:0012880)2.53551314
24Broad alveolar ridges (HP:0000187)2.48598969
25Urethral obstruction (HP:0000796)2.47821694
26Anal stenosis (HP:0002025)2.45479357
27Neoplasm of the oral cavity (HP:0100649)2.45458574
28Colon cancer (HP:0003003)2.43974457
29Supernumerary bones of the axial skeleton (HP:0009144)2.43415812
30Diastasis recti (HP:0001540)2.43136964
31Obsessive-compulsive behavior (HP:0000722)2.41639906
32Patellar aplasia (HP:0006443)2.38648674
33Abnormal number of erythroid precursors (HP:0012131)2.38455488
34Facial hemangioma (HP:0000329)2.36212711
35Abnormality of the astrocytes (HP:0100707)2.34824923
36Astrocytoma (HP:0009592)2.34824923
37Abnormal lung lobation (HP:0002101)2.34590585
38Pallor (HP:0000980)2.32351079
39Deep venous thrombosis (HP:0002625)2.32064513
40Multiple enchondromatosis (HP:0005701)2.31334407
41Oligodactyly (HP:0012165)2.31079131
42Supernumerary spleens (HP:0009799)2.30666318
43Chromosomal breakage induced by crosslinking agents (HP:0003221)2.30003263
44Birth length less than 3rd percentile (HP:0003561)2.28499167
45Absent radius (HP:0003974)2.28006193
46Vertebral arch anomaly (HP:0008438)2.27840836
47Horseshoe kidney (HP:0000085)2.26300552
4811 pairs of ribs (HP:0000878)2.26067158
49Aplasia/Hypoplasia of the sternum (HP:0006714)2.25059952
50Triphalangeal thumb (HP:0001199)2.24479794
51Renal duplication (HP:0000075)2.23945224
52Trigonocephaly (HP:0000243)2.23730605
53Microvesicular hepatic steatosis (HP:0001414)2.23248525
54Irregular epiphyses (HP:0010582)2.22442143
55Hyperacusis (HP:0010780)2.21996535
56Abnormality of the 4th metacarpal (HP:0010012)2.20564419
57Embryonal neoplasm (HP:0002898)2.20375915
58Aplasia/Hypoplasia of the patella (HP:0006498)2.19197071
59Prolonged partial thromboplastin time (HP:0003645)2.17440847
60Septo-optic dysplasia (HP:0100842)2.17110974
61High anterior hairline (HP:0009890)2.16320563
62Pancreatic islet-cell hyperplasia (HP:0004510)2.14791714
63Pendular nystagmus (HP:0012043)2.14438513
64Morphological abnormality of the inner ear (HP:0011390)2.13316715
65Absent forearm bone (HP:0003953)2.11645971
66Aplasia involving forearm bones (HP:0009822)2.11645971
67Truncal obesity (HP:0001956)2.09404978
68Cutis marmorata (HP:0000965)2.09340257
69Abnormality of chromosome stability (HP:0003220)2.08982127
70Glioma (HP:0009733)2.07775655
71Sloping forehead (HP:0000340)2.07612858
72Skin tags (HP:0010609)2.06186803
73Broad thumb (HP:0011304)2.04818902
74Low anterior hairline (HP:0000294)2.04247903
75Small epiphyses (HP:0010585)2.03342468
76Atresia of the external auditory canal (HP:0000413)2.02095150
77Deep philtrum (HP:0002002)2.02088731
78Overlapping toe (HP:0001845)2.02051323
79Myelodysplasia (HP:0002863)1.99128320
80Rib fusion (HP:0000902)1.98278447
81Skull defect (HP:0001362)1.97661022
82Oligodactyly (hands) (HP:0001180)1.97386833
83Neoplasm of striated muscle (HP:0009728)1.97167944
84Basal cell carcinoma (HP:0002671)1.96563881
85Midline defect of the nose (HP:0004122)1.94413412
86Meckel diverticulum (HP:0002245)1.93255757
87Selective tooth agenesis (HP:0001592)1.92103846
88Narrow palate (HP:0000189)1.91667687
89Abnormality of the intervertebral disk (HP:0005108)1.91488088
90Sparse lateral eyebrow (HP:0005338)1.90607402
91Microtia (HP:0008551)1.88160356
92Abnormality of the duodenum (HP:0002246)1.87899070
93Heterotopia (HP:0002282)1.87709494
94Macroorchidism (HP:0000053)1.87655659
95Papillary thyroid carcinoma (HP:0002895)1.87552300
96Cortical dysplasia (HP:0002539)1.87517095
97Abnormality of the preputium (HP:0100587)1.86940641
98Deep palmar crease (HP:0006191)1.86785237
99Preauricular skin tag (HP:0000384)1.86276298
100Renovascular hypertension (HP:0100817)1.84921657
101Abnormality of the carotid arteries (HP:0005344)1.84486770
102Missing ribs (HP:0000921)1.84077835
103Abnormality of the columella (HP:0009929)1.83805821
104Blepharitis (HP:0000498)1.83372397
105Acute lymphatic leukemia (HP:0006721)1.83121876
106Abnormality of the incisor (HP:0000676)1.83013647
107Abnormality of the ileum (HP:0001549)1.83006992
108Rhabdomyosarcoma (HP:0002859)1.82650122
109Abnormality of DNA repair (HP:0003254)1.82272794
110Acute myeloid leukemia (HP:0004808)1.81703956
111Shawl scrotum (HP:0000049)1.81528722
112High pitched voice (HP:0001620)1.81479462
113Aplasia/Hypoplasia of the uvula (HP:0010293)1.81180644
114Elfin facies (HP:0004428)1.81013147
115Abnormality of the nasal septum (HP:0000419)1.79393122
116Duplication of thumb phalanx (HP:0009942)1.78441878
117Anophthalmia (HP:0000528)1.78373017
118Gonadotropin excess (HP:0000837)1.78226092
119Absent thumb (HP:0009777)1.77931543
120Impulsivity (HP:0100710)1.77668235
121Capillary hemangiomas (HP:0005306)1.76834659
122Abnormality of the parietal bone (HP:0002696)1.76591291
123Overriding aorta (HP:0002623)1.76504356
124Rectal prolapse (HP:0002035)1.75558277
125Sandal gap (HP:0001852)1.75374172
126Intestinal fistula (HP:0100819)1.74683627
127Thick eyebrow (HP:0000574)1.74081765
128Broad phalanges of the hand (HP:0009768)1.73283752
129Cafe-au-lait spot (HP:0000957)1.73124457
130Malignant gastrointestinal tract tumors (HP:0006749)1.72767182
131Gastrointestinal carcinoma (HP:0002672)1.72767182
132Abnormality of chromosome segregation (HP:0002916)1.72714235
133Pseudobulbar signs (HP:0002200)1.71563533
134Progressive external ophthalmoplegia (HP:0000590)1.71472204
135Broad palm (HP:0001169)1.71038930
136Abnormality of the diencephalon (HP:0010662)1.70103436
137Lip pit (HP:0100267)1.69147561
138Sacral dimple (HP:0000960)1.68823750
139Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.67804567
140Absent epiphyses (HP:0010577)1.67804567
141Spina bifida occulta (HP:0003298)1.66149943
142Small intestinal stenosis (HP:0012848)1.65915157
143Duodenal stenosis (HP:0100867)1.65915157
144Smooth philtrum (HP:0000319)1.65630025
145Bicuspid aortic valve (HP:0001647)1.64826361
146Abnormal biliary tract physiology (HP:0012439)1.64495447
147Bile duct proliferation (HP:0001408)1.64495447
148Premature ovarian failure (HP:0008209)1.63971625
149Combined immunodeficiency (HP:0005387)1.61897798
150Hyperglycinuria (HP:0003108)1.60884645
151Vaginal fistula (HP:0004320)1.60814485
152Abnormality of the septum pellucidum (HP:0007375)1.59791401
153Choanal atresia (HP:0000453)1.59314471
154Rectovaginal fistula (HP:0000143)1.58314744
155Rectal fistula (HP:0100590)1.58314744
156Facial cleft (HP:0002006)1.56327765
157Hypoplasia of the capital femoral epiphysis (HP:0003090)1.56295382
158Severe combined immunodeficiency (HP:0004430)1.55910638

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC75.47934107
2CDK125.24660196
3BRD43.19808130
4NEK22.94370803
5SRPK12.76661746
6MKNK12.32889177
7EEF2K2.23616889
8VRK21.98906289
9TTK1.98842959
10SIK21.98072043
11MKNK21.89855325
12ATR1.86156521
13TAF11.84555612
14LATS11.83945331
15WEE11.80745890
16CDK71.74747839
17CHEK11.68861316
18TNIK1.68136316
19CAMK1G1.64511286
20NME11.62064103
21STK161.57618859
22MAP3K101.56451727
23CHEK21.50868414
24CAMK1D1.50491539
25CDK41.50143099
26ALK1.48608829
27EIF2AK31.43421982
28CDK81.41869476
29WNK41.40803758
30PNCK1.40158945
31RPS6KB21.39773641
32ATM1.39035541
33CDK61.38874566
34STK101.36371168
35TSSK61.36368433
36AURKB1.36075602
37MTOR1.35188178
38BUB11.32524796
39NEK11.31245097
40CDK21.30035064
41PLK11.29256358
42PKN21.27947158
43PASK1.25642189
44PLK31.24041607
45BRSK21.22163185
46PBK1.20395867
47FGFR41.20341025
48RPS6KA41.12783473
49PLK41.10026290
50CDK11.09432278
51STK31.08290320
52SMG11.05324415
53ACVR1B1.00036673
54FGFR20.98320277
55BRSK10.96515075
56CSNK1E0.94954953
57NUAK10.93508172
58EIF2AK20.89180785
59FGFR10.87235379
60PAK40.85196489
61CDK90.84094326
62MAP4K10.82453922
63CCNB10.81637963
64MAPK140.79691954
65MELK0.79260406
66PRKDC0.79016575
67MAP3K80.76854647
68PAK20.74534426
69GSK3B0.73540858
70EIF2AK10.73278004
71VRK10.72365491
72CSNK1D0.67853516
73MARK20.67654640
74TYRO30.65373440
75TGFBR10.65015716
76AKT20.64766789
77MAPK100.64658122
78BMPR1B0.64370288
79DMPK0.64067286
80MAP3K70.61801070
81SIK30.61789357
82STK40.61712644
83CSNK2A10.61483392
84MARK30.60726235
85DYRK20.57931570
86DYRK30.57064092
87SIK10.56730289
88CSNK2A20.56379666
89LATS20.54675496
90TRIB30.52954550
91PDGFRB0.52835683
92AKT10.50460498
93MAPK80.49281934
94MAPK10.48933973
95CDC42BPA0.48399037
96PRKD20.47993923
97ITK0.47779710
98RPS6KA10.47721178
99ICK0.47578900
100CDK30.47349530
101BCR0.47278191
102ILK0.46918421
103TESK20.46744034
104FGFR30.46666950
105CAMK40.46133365
106CLK10.45545288
107TAOK10.44860342
108TEC0.44155629
109PIK3CA0.44007735
110PTK60.43928727
111CDK190.43051941
112LRRK20.42953744
113SCYL20.42197177
114WNK10.41878705
115UHMK10.40084080
116MAP3K60.39361132
117SGK10.38865393
118KSR10.37716415
119MAPK90.36063992
120PRKCI0.34378996
121ZAK0.33895424
122STK38L0.32879203
123RPS6KB10.32282083
124STK380.31952471
125CDK11A0.31705513
126DYRK1A0.31650345
127RAF10.31476667
128PDGFRA0.31314263
129AURKA0.30386335
130PRKACB0.28444223
131YES10.28176804
132MAPKAPK50.27195719
133CSNK1A10.25240690
134MAP3K40.24771890
135* RPS6KA30.24472637

Predicted pathways (KEGG)

RankGene SetZ-score
1Spliceosome_Homo sapiens_hsa030403.67328955
2DNA replication_Homo sapiens_hsa030303.19501637
3Cell cycle_Homo sapiens_hsa041102.92524443
4* RNA transport_Homo sapiens_hsa030132.89427629
5Mismatch repair_Homo sapiens_hsa034302.85086425
6* mRNA surveillance pathway_Homo sapiens_hsa030152.76407269
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.66777582
8RNA degradation_Homo sapiens_hsa030182.37879540
9Base excision repair_Homo sapiens_hsa034102.02880501
10Non-homologous end-joining_Homo sapiens_hsa034501.98906986
11Homologous recombination_Homo sapiens_hsa034401.94256029
12Fanconi anemia pathway_Homo sapiens_hsa034601.88704779
13Nucleotide excision repair_Homo sapiens_hsa034201.87941163
14Basal transcription factors_Homo sapiens_hsa030221.87676457
15Protein export_Homo sapiens_hsa030601.69039961
16Lysine degradation_Homo sapiens_hsa003101.60227342
17RNA polymerase_Homo sapiens_hsa030201.59979169
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.57265711
19Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.52489856
20MicroRNAs in cancer_Homo sapiens_hsa052061.51660190
21Basal cell carcinoma_Homo sapiens_hsa052171.43480531
22Colorectal cancer_Homo sapiens_hsa052101.40037263
23Primary immunodeficiency_Homo sapiens_hsa053401.39849277
24Oocyte meiosis_Homo sapiens_hsa041141.38726301
25Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.36735118
26One carbon pool by folate_Homo sapiens_hsa006701.35919517
27Notch signaling pathway_Homo sapiens_hsa043301.35722031
28Chronic myeloid leukemia_Homo sapiens_hsa052201.34171142
29Cysteine and methionine metabolism_Homo sapiens_hsa002701.29779198
30p53 signaling pathway_Homo sapiens_hsa041151.28589545
31Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.26606974
32HTLV-I infection_Homo sapiens_hsa051661.25139286
33mTOR signaling pathway_Homo sapiens_hsa041501.20569865
34Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.15455233
35Transcriptional misregulation in cancer_Homo sapiens_hsa052021.14438920
36Small cell lung cancer_Homo sapiens_hsa052221.11350280
37Selenocompound metabolism_Homo sapiens_hsa004501.09627015
38Hippo signaling pathway_Homo sapiens_hsa043901.08847182
39Wnt signaling pathway_Homo sapiens_hsa043101.07795678
40Herpes simplex infection_Homo sapiens_hsa051681.07535686
41Non-small cell lung cancer_Homo sapiens_hsa052231.05063093
42Proteasome_Homo sapiens_hsa030501.05014098
43Adherens junction_Homo sapiens_hsa045201.03852419
44Hedgehog signaling pathway_Homo sapiens_hsa043401.02908615
45Epstein-Barr virus infection_Homo sapiens_hsa051691.02783533
46T cell receptor signaling pathway_Homo sapiens_hsa046601.00953649
47Pancreatic cancer_Homo sapiens_hsa052121.00876026
48Endometrial cancer_Homo sapiens_hsa052131.00016965
49Thyroid hormone signaling pathway_Homo sapiens_hsa049190.99096531
50Steroid biosynthesis_Homo sapiens_hsa001000.98626864
51Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.98385113
52Prostate cancer_Homo sapiens_hsa052150.98296198
53Ribosome_Homo sapiens_hsa030100.97865025
54TGF-beta signaling pathway_Homo sapiens_hsa043500.95115974
55Viral carcinogenesis_Homo sapiens_hsa052030.95073184
56Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.93223862
57Biosynthesis of amino acids_Homo sapiens_hsa012300.93041161
58Pyrimidine metabolism_Homo sapiens_hsa002400.90077917
59Vitamin digestion and absorption_Homo sapiens_hsa049770.89877990
60Renal cell carcinoma_Homo sapiens_hsa052110.89840193
61Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.88521898
62Antigen processing and presentation_Homo sapiens_hsa046120.88311623
63Propanoate metabolism_Homo sapiens_hsa006400.86404976
64Thyroid cancer_Homo sapiens_hsa052160.83532496
65Pathways in cancer_Homo sapiens_hsa052000.79580373
66Proteoglycans in cancer_Homo sapiens_hsa052050.79501965
67Glioma_Homo sapiens_hsa052140.77861535
68Acute myeloid leukemia_Homo sapiens_hsa052210.76676677
69Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.75664488
70Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.75171633
71B cell receptor signaling pathway_Homo sapiens_hsa046620.70948383
72Hepatitis B_Homo sapiens_hsa051610.69589344
73Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.69541205
74Viral myocarditis_Homo sapiens_hsa054160.69380780
75Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.68170928
76FoxO signaling pathway_Homo sapiens_hsa040680.67517411
77Pyruvate metabolism_Homo sapiens_hsa006200.66976168
78Neurotrophin signaling pathway_Homo sapiens_hsa047220.62049131
79Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.60556004
80Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.58222974
81Fatty acid metabolism_Homo sapiens_hsa012120.57551479
82ErbB signaling pathway_Homo sapiens_hsa040120.57054942
83Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.55716497
84Central carbon metabolism in cancer_Homo sapiens_hsa052300.55079177
85Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.54644647
86Estrogen signaling pathway_Homo sapiens_hsa049150.54005930
87HIF-1 signaling pathway_Homo sapiens_hsa040660.53226156
88Huntingtons disease_Homo sapiens_hsa050160.53123171
89Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.52303758
90Circadian rhythm_Homo sapiens_hsa047100.51908617
91Longevity regulating pathway - mammal_Homo sapiens_hsa042110.50791153
92Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.49841228
93Melanoma_Homo sapiens_hsa052180.49758931
94Purine metabolism_Homo sapiens_hsa002300.49549062
95Carbon metabolism_Homo sapiens_hsa012000.48356749
96Platelet activation_Homo sapiens_hsa046110.47940507
97Tight junction_Homo sapiens_hsa045300.47652452
98Leukocyte transendothelial migration_Homo sapiens_hsa046700.46936535
99Choline metabolism in cancer_Homo sapiens_hsa052310.46870696
100Melanogenesis_Homo sapiens_hsa049160.46342732
101MAPK signaling pathway_Homo sapiens_hsa040100.46144308
102Focal adhesion_Homo sapiens_hsa045100.45710230
103Glucagon signaling pathway_Homo sapiens_hsa049220.45447904
104Phototransduction_Homo sapiens_hsa047440.45413824
105Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.45157247
106Long-term potentiation_Homo sapiens_hsa047200.44929948
107Bladder cancer_Homo sapiens_hsa052190.44560744
108Regulation of actin cytoskeleton_Homo sapiens_hsa048100.44106240
109Axon guidance_Homo sapiens_hsa043600.42064332
110Rap1 signaling pathway_Homo sapiens_hsa040150.42047150
111Prolactin signaling pathway_Homo sapiens_hsa049170.41774136
112Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.41462862
113AMPK signaling pathway_Homo sapiens_hsa041520.41395629
114Type II diabetes mellitus_Homo sapiens_hsa049300.40383147
115Dorso-ventral axis formation_Homo sapiens_hsa043200.40017592
116Butanoate metabolism_Homo sapiens_hsa006500.39577464
117VEGF signaling pathway_Homo sapiens_hsa043700.39024840
118cGMP-PKG signaling pathway_Homo sapiens_hsa040220.38937305
119Measles_Homo sapiens_hsa051620.36160250
120PI3K-Akt signaling pathway_Homo sapiens_hsa041510.35198188
121Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.34644421
122Phosphatidylinositol signaling system_Homo sapiens_hsa040700.33996664
123Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.33706285
1242-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.33678490
125Hematopoietic cell lineage_Homo sapiens_hsa046400.33636327
126Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.31127026
127Thyroid hormone synthesis_Homo sapiens_hsa049180.30083179
128Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.27726874
129Maturity onset diabetes of the young_Homo sapiens_hsa049500.27394357
130Parkinsons disease_Homo sapiens_hsa050120.26992378
131Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.24839188
132Fat digestion and absorption_Homo sapiens_hsa049750.24818468
133Fatty acid degradation_Homo sapiens_hsa000710.22357111
134Metabolic pathways_Homo sapiens_hsa011000.22268805
135Pentose and glucuronate interconversions_Homo sapiens_hsa000400.19506533
136Complement and coagulation cascades_Homo sapiens_hsa046100.19109716
137N-Glycan biosynthesis_Homo sapiens_hsa005100.14622563
138Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.14576356
139Cyanoamino acid metabolism_Homo sapiens_hsa004600.12926585
140Fatty acid biosynthesis_Homo sapiens_hsa000610.08723806
141Drug metabolism - other enzymes_Homo sapiens_hsa009830.08509330
142Arginine and proline metabolism_Homo sapiens_hsa003300.07919335
143Fatty acid elongation_Homo sapiens_hsa000620.06369107

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