PLAGL2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Pleiomorphic adenoma gene-like 2 is a zinc-finger protein that recognizes DNA and/or RNA. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)4.48212725
2mitotic chromosome condensation (GO:0007076)4.36124699
3leukocyte aggregation (GO:0070486)3.76189846
4histone H3-K36 demethylation (GO:0070544)3.69892005
5modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.59442705
6positive regulation by organism of defense response of other organism involved in symbiotic interact3.59442705
7modulation by symbiont of host immune response (GO:0052553)3.59442705
8positive regulation by symbiont of host defense response (GO:0052509)3.59442705
9modulation by symbiont of host defense response (GO:0052031)3.59442705
10modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.59442705
11regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.59198644
12regulation of RNA export from nucleus (GO:0046831)3.58913381
13antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.46302959
14regulation of gamma-delta T cell differentiation (GO:0045586)3.39215223
15regulation of NFAT protein import into nucleus (GO:0051532)3.37717321
16antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.37662395
17antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.37662395
18regulation of gamma-delta T cell activation (GO:0046643)3.37036566
19tolerance induction (GO:0002507)3.32776504
20positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.32344330
21negative regulation of histone methylation (GO:0031061)3.31949498
22regulation of interleukin-12 biosynthetic process (GO:0045075)3.20984235
23negative regulation of erythrocyte differentiation (GO:0045647)3.18674451
24heterochromatin organization (GO:0070828)3.13634094
25neutrophil activation involved in immune response (GO:0002283)3.12092963
26regulation of histone H3-K27 methylation (GO:0061085)3.08936767
273-UTR-mediated mRNA stabilization (GO:0070935)3.08910350
28negative thymic T cell selection (GO:0045060)3.04434859
29chromosome condensation (GO:0030261)3.04352894
30regulation of nucleobase-containing compound transport (GO:0032239)3.02075634
31antigen processing and presentation of endogenous antigen (GO:0019883)3.01689244
32DNA unwinding involved in DNA replication (GO:0006268)3.00273310
33negative T cell selection (GO:0043383)3.00209366
34regulation of podosome assembly (GO:0071801)2.99538060
35regulation of vitamin D biosynthetic process (GO:0060556)2.96954930
36positive regulation of B cell differentiation (GO:0045579)2.91962238
37immunoglobulin mediated immune response (GO:0016064)2.91769128
38response to peptidoglycan (GO:0032494)2.91669838
39NIK/NF-kappaB signaling (GO:0038061)2.90862613
40positive regulation of isotype switching (GO:0045830)2.89640835
41positive regulation of gene expression, epigenetic (GO:0045815)2.88090675
42nuclear pore complex assembly (GO:0051292)2.85190025
43pre-miRNA processing (GO:0031054)2.85006089
44myeloid dendritic cell activation (GO:0001773)2.82810714
45regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.82435052
46modulation by symbiont of host cellular process (GO:0044068)2.81484050
47myeloid dendritic cell differentiation (GO:0043011)2.80676744
48positive regulation of natural killer cell differentiation (GO:0032825)2.80460609
49response to muramyl dipeptide (GO:0032495)2.79248363
50negative regulation of interleukin-12 production (GO:0032695)2.77224046
51positive regulation of interleukin-2 production (GO:0032743)2.74210762
52regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.73955142
53positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.72986715
54positive regulation of interferon-alpha production (GO:0032727)2.72133661
55DNA packaging (GO:0006323)2.72103451
56modulation by virus of host process (GO:0019054)2.72038961
57regulation of interleukin-2 biosynthetic process (GO:0045076)2.72032594
58positive thymic T cell selection (GO:0045059)2.71920182
59cellular response to virus (GO:0098586)2.71698263
60T cell migration (GO:0072678)2.71167216
61JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.70949620
62regulation of interferon-alpha production (GO:0032647)2.69911046
63positive regulation of B cell mediated immunity (GO:0002714)2.67746327
64positive regulation of immunoglobulin mediated immune response (GO:0002891)2.67746327
65mitotic sister chromatid segregation (GO:0000070)2.65890078
66positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.65662226
67intracellular estrogen receptor signaling pathway (GO:0030520)2.65530617
68regulation of histone H3-K9 methylation (GO:0051570)2.65391628
69histone lysine demethylation (GO:0070076)2.64804163
70mitotic sister chromatid cohesion (GO:0007064)2.61480571
71regulation of B cell differentiation (GO:0045577)2.59140744
72regulation of alpha-beta T cell proliferation (GO:0046640)2.58318966
73B cell mediated immunity (GO:0019724)2.58303013
74protein localization to kinetochore (GO:0034501)2.57599690
75spliceosomal tri-snRNP complex assembly (GO:0000244)2.57331630
76regulation of B cell receptor signaling pathway (GO:0050855)2.57192090
77T cell apoptotic process (GO:0070231)2.57097174
78CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.56812600
79response to type I interferon (GO:0034340)2.56214347
80histone demethylation (GO:0016577)2.56072233
81regulation of chromatin binding (GO:0035561)2.55954462
82histone H4-K16 acetylation (GO:0043984)2.55720396
83regulation of type I interferon-mediated signaling pathway (GO:0060338)2.54993633
84tyrosine phosphorylation of STAT protein (GO:0007260)2.53907500
85negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.53733510
86nuclear pore organization (GO:0006999)2.53729057
87nuclear envelope disassembly (GO:0051081)2.53260054
88membrane disassembly (GO:0030397)2.53260054
89sister chromatid segregation (GO:0000819)2.50915415
90type I interferon signaling pathway (GO:0060337)2.50811476
91cellular response to type I interferon (GO:0071357)2.50811476
92trophectodermal cell differentiation (GO:0001829)2.50335241
93Arp2/3 complex-mediated actin nucleation (GO:0034314)2.50231535
94T cell homeostasis (GO:0043029)2.49649102
95positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.49411225
96defense response to protozoan (GO:0042832)2.48907608
97positive regulation of chemokine biosynthetic process (GO:0045080)2.47202047
98embryonic process involved in female pregnancy (GO:0060136)2.46935997
99regulation of vitamin metabolic process (GO:0030656)2.46929467
100histone H3-K4 methylation (GO:0051568)2.46664277
101response to host (GO:0075136)2.45649648
102response to host defenses (GO:0052200)2.45649648
103response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.45649648
104positive regulation of humoral immune response (GO:0002922)2.45379266
105positive regulation of cytokine biosynthetic process (GO:0042108)2.44638191
106histone H3-K9 demethylation (GO:0033169)2.44220503
107trophoblast giant cell differentiation (GO:0060707)2.44169099
108response to interleukin-15 (GO:0070672)2.44069098
109regulation of RNA stability (GO:0043487)2.43804264
110mucosal-associated lymphoid tissue development (GO:0048537)2.43547104
111Peyers patch development (GO:0048541)2.43547104
112response to protozoan (GO:0001562)2.42986085
113regulation of interferon-beta biosynthetic process (GO:0045357)2.42341912
114response to host immune response (GO:0052572)2.42178316
115response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.42178316
116regulation of histone methylation (GO:0031060)2.41636342
117pinocytosis (GO:0006907)2.38786980
118natural killer cell differentiation (GO:0001779)2.38237021
119natural killer cell mediated immunity (GO:0002228)2.38061810
120natural killer cell mediated cytotoxicity (GO:0042267)2.38061810
121respiratory burst (GO:0045730)2.37448963
122histone mRNA catabolic process (GO:0071044)2.36629183
123negative regulation of toll-like receptor signaling pathway (GO:0034122)2.36619339
124mRNA stabilization (GO:0048255)2.36538118
125RNA stabilization (GO:0043489)2.36538118
126negative regulation of cell killing (GO:0031342)2.36533600
127negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.36533600
128histone H3-K4 trimethylation (GO:0080182)2.36173669
129DNA topological change (GO:0006265)2.36099331
130protein localization to chromosome, centromeric region (GO:0071459)2.35520189
131T cell lineage commitment (GO:0002360)2.34923722
132thymic T cell selection (GO:0045061)2.34625302
133positive regulation of DNA recombination (GO:0045911)2.34051035
134germinal center formation (GO:0002467)2.33733432
135lipopolysaccharide-mediated signaling pathway (GO:0031663)2.33232565
136kinetochore organization (GO:0051383)2.32864801
137granulocyte activation (GO:0036230)2.32044220
138pore complex assembly (GO:0046931)2.31955298
139N-terminal protein amino acid acetylation (GO:0006474)2.31543930
140DNA strand elongation involved in DNA replication (GO:0006271)2.31272938
141leukocyte cell-cell adhesion (GO:0007159)2.31007856
142lymphocyte homeostasis (GO:0002260)2.30964830
143negative regulation of B cell proliferation (GO:0030889)2.29047174
144mitotic nuclear envelope disassembly (GO:0007077)2.28244564
145neutrophil activation (GO:0042119)2.28182072
146DNA strand elongation (GO:0022616)2.27917611
147histone H4-K8 acetylation (GO:0043982)2.27622883
148histone H4-K5 acetylation (GO:0043981)2.27622883
149positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.26928054
150glucocorticoid receptor signaling pathway (GO:0042921)2.26834588
151interferon-gamma-mediated signaling pathway (GO:0060333)2.25721537
152macrophage activation involved in immune response (GO:0002281)2.25268919
153positive regulation of macrophage differentiation (GO:0045651)2.24521389
154positive regulation of T cell cytokine production (GO:0002726)2.24173228

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.13582439
2EGR1_19374776_ChIP-ChIP_THP-1_Human4.00825291
3BP1_19119308_ChIP-ChIP_Hs578T_Human3.93817824
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.92069129
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.86011293
6IRF8_22096565_ChIP-ChIP_GC-B_Human3.31034314
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.26982698
8MYC_22102868_ChIP-Seq_BL_Human3.02145689
9IRF8_21731497_ChIP-ChIP_J774_Mouse3.00137527
10E2F4_17652178_ChIP-ChIP_JURKAT_Human2.82021936
11IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.75794804
12MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.64846442
13NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.63030632
14VDR_21846776_ChIP-Seq_THP-1_Human2.52229683
15IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.35333739
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.33801380
17EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.33564022
18SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.33182372
19* STAT4_19710469_ChIP-ChIP_TH1__Mouse2.27016756
20STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.24165314
21MYB_21317192_ChIP-Seq_ERMYB_Mouse2.23311579
22ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.22870395
23* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.21374980
24SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.16760837
25IRF8_27001747_Chip-Seq_BMDM_Mouse2.15560781
26SCL_19346495_ChIP-Seq_HPC-7_Human2.13070306
27MYB_26560356_Chip-Seq_TH2_Human2.05181595
28SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.04489140
29* MAF_26560356_Chip-Seq_TH1_Human1.99184719
30SPI1_23547873_ChIP-Seq_NB4_Human1.92411659
31VDR_24763502_ChIP-Seq_THP-1_Human1.85061382
32UTX_26944678_Chip-Seq_JUKART_Human1.79651440
33MYB_26560356_Chip-Seq_TH1_Human1.78679892
34HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.76099661
35BRD4_27068464_Chip-Seq_AML-cells_Mouse1.74457752
36TCF7_22412390_ChIP-Seq_EML_Mouse1.73310839
37MYC_18555785_ChIP-Seq_MESCs_Mouse1.72422500
38CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.71940200
39FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.68979361
40STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.67446553
41RUNX1_22412390_ChIP-Seq_EML_Mouse1.65314781
42E2F1_21310950_ChIP-Seq_MCF-7_Human1.63644873
43RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.60966581
44TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.60040938
45ELF1_17652178_ChIP-ChIP_JURKAT_Human1.54776924
46TP63_19390658_ChIP-ChIP_HaCaT_Human1.51624265
47RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.50094138
48CIITA_25753668_ChIP-Seq_RAJI_Human1.46504566
49POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.41615661
50RUNX_20019798_ChIP-Seq_JUKART_Human1.41153759
51* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.40343286
52SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.39020594
53FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.37453554
54CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.36574837
55NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.33494123
56TP63_17297297_ChIP-ChIP_HaCaT_Human1.31828734
57MAF_26560356_Chip-Seq_TH2_Human1.31813945
58SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.31208950
59KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.31030060
60KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.31030060
61KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.31030060
62KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.29041726
63KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.28877379
64STAT6_21828071_ChIP-Seq_BEAS2B_Human1.27625259
65AR_21909140_ChIP-Seq_LNCAP_Human1.26275239
66SPI1_23127762_ChIP-Seq_K562_Human1.23082291
67* PU_27001747_Chip-Seq_BMDM_Mouse1.21394303
68HOXB4_20404135_ChIP-ChIP_EML_Mouse1.21116415
69* NOTCH1_21737748_ChIP-Seq_TLL_Human1.21110170
70RACK7_27058665_Chip-Seq_MCF-7_Human1.20341423
71MYC_19079543_ChIP-ChIP_MESCs_Mouse1.19725105
72XRN2_22483619_ChIP-Seq_HELA_Human1.19383050
73TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.17852061
74GATA2_22383799_ChIP-Seq_G1ME_Mouse1.17088893
75KLF4_18555785_ChIP-Seq_MESCs_Mouse1.17011224
76STAT3_1855785_ChIP-Seq_MESCs_Mouse1.16069618
77KDM2B_26808549_Chip-Seq_DND41_Human1.15730271
78GATA1_22383799_ChIP-Seq_G1ME_Mouse1.15249218
79LXR_22292898_ChIP-Seq_THP-1_Human1.14671490
80GATA3_27048872_Chip-Seq_THYMUS_Human1.13977068
81* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.13545792
82* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.12553009
83ELK3_25401928_ChIP-Seq_HUVEC_Human1.12007107
84* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.11387137
85ERG_20887958_ChIP-Seq_HPC-7_Mouse1.10585862
86TFEB_21752829_ChIP-Seq_HELA_Human1.10449493
87MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.09859827
88E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.09207083
89VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.08826135
90FOXP3_21729870_ChIP-Seq_TREG_Human1.06936661
91KDM2B_26808549_Chip-Seq_JURKAT_Human1.06716709
92GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.06450699
93DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.06426961
94VDR_23849224_ChIP-Seq_CD4+_Human1.06140914
95ELK1_19687146_ChIP-ChIP_HELA_Human1.04183716
96TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03528059
97Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.02570981
98KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.00831525
99ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.00203590
100NELFA_20434984_ChIP-Seq_ESCs_Mouse0.99574684
101CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.99087952
102ZNF263_19887448_ChIP-Seq_K562_Human0.97578967
103* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.96999306
104CREB1_15753290_ChIP-ChIP_HEK293T_Human0.95974391
105* KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.95879179
106CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.95016768
107MYC_18358816_ChIP-ChIP_MESCs_Mouse0.94297360
108* CHD1_26751641_Chip-Seq_LNCaP_Human0.93346467
109FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.93280864
110EST1_17652178_ChIP-ChIP_JURKAT_Human0.92325250
111KDM5A_27292631_Chip-Seq_BREAST_Human0.91348939
112NCOR1_26117541_ChIP-Seq_K562_Human0.90069830
113KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.88295206
114PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.87097277
115TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.87045717
116E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.85518640
117MYCN_18555785_ChIP-Seq_MESCs_Mouse0.83690655
118KDM2B_26808549_Chip-Seq_SUP-B15_Human0.83672489
119PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.81521301
120TTF2_22483619_ChIP-Seq_HELA_Human0.81408015
121LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.81396615
122MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.80655526
123GATA1_22025678_ChIP-Seq_K562_Human0.80267032
124GATA1_19941827_ChIP-Seq_MEL_Mouse0.79042469
125* CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.78821682

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003436_decreased_susceptibility_to3.11644652
2MP0005451_abnormal_body_composition3.05935518
3MP0001835_abnormal_antigen_presentation2.94843077
4MP0003303_peritoneal_inflammation2.82036688
5MP0005671_abnormal_response_to2.72605781
6MP0009785_altered_susceptibility_to2.72203486
7MP0000685_abnormal_immune_system2.71544750
8MP0005000_abnormal_immune_tolerance2.46250362
9MP0001800_abnormal_humoral_immune2.45761634
10MP0005387_immune_system_phenotype2.44774002
11MP0001790_abnormal_immune_system2.44774002
12MP0002396_abnormal_hematopoietic_system2.38395147
13MP0003763_abnormal_thymus_physiology2.36705888
14MP0002452_abnormal_antigen_presenting2.29589295
15MP0005025_abnormal_response_to2.26191777
16MP0005076_abnormal_cell_differentiation2.23091119
17MP0002723_abnormal_immune_serum2.19873793
18MP0008057_abnormal_DNA_replication2.16110828
19MP0003693_abnormal_embryo_hatching2.15895797
20MP0002148_abnormal_hypersensitivity_rea2.15731900
21MP0002398_abnormal_bone_marrow2.13047149
22MP0002419_abnormal_innate_immunity2.12036175
23MP0002420_abnormal_adaptive_immunity2.10839742
24MP0003300_gastrointestinal_ulcer2.10452942
25MP0001819_abnormal_immune_cell2.10278672
26MP0004808_abnormal_hematopoietic_stem2.07219333
27MP0002405_respiratory_system_inflammati2.07168848
28MP0010352_gastrointestinal_tract_polyps2.06454369
29MP0009278_abnormal_bone_marrow2.06338574
30MP0009333_abnormal_splenocyte_physiolog2.02425469
31MP0010094_abnormal_chromosome_stability1.94622871
32MP0010155_abnormal_intestine_physiology1.93998137
33MP0001545_abnormal_hematopoietic_system1.85738605
34MP0005397_hematopoietic_system_phenotyp1.85738605
35MP0000490_abnormal_crypts_of1.82521990
36MP0000716_abnormal_immune_system1.81590534
37MP0003077_abnormal_cell_cycle1.78458937
38MP0002722_abnormal_immune_system1.77133640
39MP0003111_abnormal_nucleus_morphology1.76269761
40MP0000689_abnormal_spleen_morphology1.72578895
41MP0000703_abnormal_thymus_morphology1.69560633
42MP0002166_altered_tumor_susceptibility1.68578503
43MP0001853_heart_inflammation1.67547530
44MP0004264_abnormal_extraembryonic_tissu1.66745883
45MP0006082_CNS_inflammation1.65785530
46MP0004947_skin_inflammation1.63171491
47MP0002429_abnormal_blood_cell1.62996795
48MP0003724_increased_susceptibility_to1.59717659
49MP0005464_abnormal_platelet_physiology1.56733604
50MP0002006_tumorigenesis1.55048314
51MP0010307_abnormal_tumor_latency1.50635748
52MP0001845_abnormal_inflammatory_respons1.48997674
53MP0001533_abnormal_skeleton_physiology1.46217429
54MP0003866_abnormal_defecation1.44901670
55MP0004185_abnormal_adipocyte_glucose1.42552513
56MP0001873_stomach_inflammation1.40596945
57MP0004957_abnormal_blastocyst_morpholog1.40542624
58MP0003448_altered_tumor_morphology1.35422015
59MP0004510_myositis1.33921745
60MP0002933_joint_inflammation1.27279778
61MP0000858_altered_metastatic_potential1.24539706
62MP0008007_abnormal_cellular_replicative1.22558043
63MP0008260_abnormal_autophagy1.21105656
64MP0002132_abnormal_respiratory_system1.16741768
65MP0010234_abnormal_vibrissa_follicle1.15568907
66MP0000350_abnormal_cell_proliferation1.14559631
67MP0008058_abnormal_DNA_repair1.13962897
68MP0000569_abnormal_digit_pigmentation1.12905243
69MP0002019_abnormal_tumor_incidence1.10578622
70MP0002089_abnormal_postnatal_growth/wei1.07305449
71MP0002139_abnormal_hepatobiliary_system1.06340019
72MP0005310_abnormal_salivary_gland1.05044846
73MP0005174_abnormal_tail_pigmentation1.02797481
74MP0005023_abnormal_wound_healing1.00353895
75MP0000313_abnormal_cell_death1.00294527
76MP0008469_abnormal_protein_level1.00292518
77MP0003091_abnormal_cell_migration0.98873902
78MP0003123_paternal_imprinting0.98003169
79MP0000465_gastrointestinal_hemorrhage0.95099837
80MP0005409_darkened_coat_color0.94205882
81MP0003221_abnormal_cardiomyocyte_apopto0.93973135
82MP0009672_abnormal_birth_weight0.92727134
83MP0000566_synostosis0.92472024
84MP0001730_embryonic_growth_arrest0.91573662
85MP0005621_abnormal_cell_physiology0.90300568
86MP0009764_decreased_sensitivity_to0.89433168
87MP0003828_pulmonary_edema0.88861787
88MP0009840_abnormal_foam_cell0.88643055
89MP0005666_abnormal_adipose_tissue0.88537628
90MP0000609_abnormal_liver_physiology0.87920741
91MP0002009_preneoplasia0.87697125
92MP0003705_abnormal_hypodermis_morpholog0.87598672
93MP0003718_maternal_effect0.87030675
94MP0000678_abnormal_parathyroid_gland0.85162564
95MP0000343_altered_response_to0.84677009
96MP0001346_abnormal_lacrimal_gland0.83808442
97MP0009115_abnormal_fat_cell0.81442332
98MP0003984_embryonic_growth_retardation0.81345474
99MP0002088_abnormal_embryonic_growth/wei0.80743200
100MP0003172_abnormal_lysosome_physiology0.79800565
101MP0005390_skeleton_phenotype0.79193627
102MP0002086_abnormal_extraembryonic_tissu0.76598263
103MP0003567_abnormal_fetal_cardiomyocyte0.75702777
104MP0001672_abnormal_embryogenesis/_devel0.74686707
105MP0005380_embryogenesis_phenotype0.74686707
106MP0005058_abnormal_lysosome_morphology0.71671227
107MP0001915_intracranial_hemorrhage0.71633833
108MP0003453_abnormal_keratinocyte_physiol0.71197148
109MP0008932_abnormal_embryonic_tissue0.71022911
110MP0002998_abnormal_bone_remodeling0.70586995
111MP0001697_abnormal_embryo_size0.69754024
112MP0002277_abnormal_respiratory_mucosa0.69023672
113MP0001663_abnormal_digestive_system0.66774917
114MP0000371_diluted_coat_color0.66657996
115MP0003566_abnormal_cell_adhesion0.66395132
116MP0003943_abnormal_hepatobiliary_system0.65631419
117MP0004197_abnormal_fetal_growth/weight/0.64822771
118MP0002080_prenatal_lethality0.63141860
119MP0001293_anophthalmia0.62205149
120MP0003656_abnormal_erythrocyte_physiolo0.61614190
121MP0006054_spinal_hemorrhage0.61475338
122MP0000733_abnormal_muscle_development0.60017010
123* MP0000477_abnormal_intestine_morphology0.59762788
124MP0001851_eye_inflammation0.59699887

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)5.03483211
2Recurrent abscess formation (HP:0002722)4.17148801
3Recurrent fungal infections (HP:0002841)3.90570424
4Recurrent viral infections (HP:0004429)3.73868950
5Mediastinal lymphadenopathy (HP:0100721)3.70059755
6Elevated erythrocyte sedimentation rate (HP:0003565)3.59024781
7Recurrent bacterial skin infections (HP:0005406)3.44037751
8Myositis (HP:0100614)3.32582609
9Abnormality of the fingertips (HP:0001211)3.30349517
10Autoimmune thrombocytopenia (HP:0001973)3.17603938
11Stomatitis (HP:0010280)3.13048146
12Obstructive lung disease (HP:0006536)3.01015106
13Chronic obstructive pulmonary disease (HP:0006510)3.01015106
14T lymphocytopenia (HP:0005403)3.00108295
15Abnormality of T cell number (HP:0011839)2.92085171
16Deep venous thrombosis (HP:0002625)2.90155600
17Thrombocytosis (HP:0001894)2.88582081
18Abnormality of macrophages (HP:0004311)2.84811905
19Orchitis (HP:0100796)2.78108874
20IgM deficiency (HP:0002850)2.76366476
21Optic neuritis (HP:0100653)2.72883007
22Retrobulbar optic neuritis (HP:0100654)2.72883007
23Abnormality of T cells (HP:0002843)2.71545287
24Recurrent cutaneous fungal infections (HP:0011370)2.71484439
25Chronic mucocutaneous candidiasis (HP:0002728)2.71484439
26Recurrent gram-negative bacterial infections (HP:0005420)2.68774440
27Progressive external ophthalmoplegia (HP:0000590)2.66266759
28Asymmetry of the thorax (HP:0001555)2.61358047
29Flat acetabular roof (HP:0003180)2.58953087
30Spontaneous hematomas (HP:0007420)2.55834626
31Severe combined immunodeficiency (HP:0004430)2.55665399
32Vasculitis (HP:0002633)2.54212193
33Panhypogammaglobulinemia (HP:0003139)2.52855963
34Syringomyelia (HP:0003396)2.51754521
35Spinal cord lesions (HP:0100561)2.51754521
36Cellulitis (HP:0100658)2.50115324
37Recurrent skin infections (HP:0001581)2.47834904
38Abnormal tarsal ossification (HP:0008369)2.46449762
39Combined immunodeficiency (HP:0005387)2.46235281
40Interstitial pulmonary disease (HP:0006530)2.43390622
41B lymphocytopenia (HP:0010976)2.42672539
42Abnormality of B cell number (HP:0010975)2.42672539
43Periodontitis (HP:0000704)2.40086602
44Leukocytosis (HP:0001974)2.39944059
45Deep palmar crease (HP:0006191)2.38412173
46Meningitis (HP:0001287)2.38168416
47Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.37757346
48Short 4th metacarpal (HP:0010044)2.37757346
49Pulmonary infiltrates (HP:0002113)2.35956485
50Gingivitis (HP:0000230)2.33875383
51Abnormal foot bone ossification (HP:0010675)2.33434713
52Pustule (HP:0200039)2.30888432
53Acute myeloid leukemia (HP:0004808)2.30356453
54Chronic diarrhea (HP:0002028)2.30117663
55Chromsome breakage (HP:0040012)2.30064108
56Increased density of long bones (HP:0006392)2.29677286
57Abnormal delayed hypersensitivity skin test (HP:0002963)2.29600114
58IgA deficiency (HP:0002720)2.28516649
59Abnormality of T cell physiology (HP:0011840)2.27805948
60Overlapping toe (HP:0001845)2.26698334
61Chronic otitis media (HP:0000389)2.25817226
62Recurrent bronchitis (HP:0002837)2.25746614
63Abnormality of cells of the lymphoid lineage (HP:0012140)2.24354969
64Lymphopenia (HP:0001888)2.24214381
65Autoimmune hemolytic anemia (HP:0001890)2.22895042
66Leiomyosarcoma (HP:0100243)2.22555510
67Uterine leiomyosarcoma (HP:0002891)2.22555510
68Petechiae (HP:0000967)2.22553962
69Gastrointestinal inflammation (HP:0004386)2.21746184
70Nephroblastoma (Wilms tumor) (HP:0002667)2.21023762
71Ectopic kidney (HP:0000086)2.20999352
72Inflammation of the large intestine (HP:0002037)2.18979208
73Lymphoma (HP:0002665)2.18376261
74Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.18078947
75Eosinophilia (HP:0001880)2.18052478
76Chest pain (HP:0100749)2.16881678
77Hereditary nonpolyposis colorectal carcinoma (HP:0006716)2.15757640
78Heterotopia (HP:0002282)2.14681057
79Hemoptysis (HP:0002105)2.11952564
80Basal ganglia calcification (HP:0002135)2.09310192
81Arterial thrombosis (HP:0004420)2.08282901
82Abnormality of the lumbar spine (HP:0100712)2.05281178
83Urethral obstruction (HP:0000796)2.03315581
84Osteomyelitis (HP:0002754)2.02341589
85Chromosomal breakage induced by crosslinking agents (HP:0003221)2.02008567
86Long eyelashes (HP:0000527)2.01825746
87Gastrointestinal stroma tumor (HP:0100723)2.01125383
88Embryonal renal neoplasm (HP:0011794)2.01046360
89Myelodysplasia (HP:0002863)2.00808335
90Increased IgE level (HP:0003212)2.00436415
91Progressive hearing impairment (HP:0001730)2.00192009
92Reticulocytopenia (HP:0001896)2.00000324
93Progressive muscle weakness (HP:0003323)1.99791525
94Thyroiditis (HP:0100646)1.99614477
95Metaphyseal cupping (HP:0003021)1.98792448
96Abnormality of eosinophils (HP:0001879)1.96166368
97Degeneration of anterior horn cells (HP:0002398)1.95640915
98Abnormality of the anterior horn cell (HP:0006802)1.95640915
99Granulocytopenia (HP:0001913)1.95508170
100Amaurosis fugax (HP:0100576)1.94897643
101Hemorrhage of the eye (HP:0011885)1.94003938
102Facial hemangioma (HP:0000329)1.92801559
103Transitional cell carcinoma of the bladder (HP:0006740)1.92409607
104Urticaria (HP:0001025)1.92050335
105Long palpebral fissure (HP:0000637)1.90240686
106Increased IgM level (HP:0003496)1.89788200
107Hyperacusis (HP:0010780)1.89579647
108Broad palm (HP:0001169)1.89220248
109Renal cell carcinoma (HP:0005584)1.89179506
110Disinhibition (HP:0000734)1.88919149
111Volvulus (HP:0002580)1.88799627
112Leukopenia (HP:0001882)1.87864617
113Agnosia (HP:0010524)1.87803332
114Gastrointestinal carcinoma (HP:0002672)1.87750875
115Malignant gastrointestinal tract tumors (HP:0006749)1.87750875
116Trigonocephaly (HP:0000243)1.86756901
117Cutis marmorata (HP:0000965)1.85314232
118Persistence of primary teeth (HP:0006335)1.84472616
119Encephalitis (HP:0002383)1.83470259
120Deep philtrum (HP:0002002)1.83253371
121Septate vagina (HP:0001153)1.83241766
122IgG deficiency (HP:0004315)1.83004168
123Acute lymphatic leukemia (HP:0006721)1.82024560
124Aplasia/Hypoplasia of the thymus (HP:0010515)1.81869076
125Abnormality of chromosome stability (HP:0003220)1.80908434
126Abnormality of the pleura (HP:0002103)1.79829006
127Anal stenosis (HP:0002025)1.79110245
128Progressive sensorineural hearing impairment (HP:0000408)1.76338753
129Deviation of the thumb (HP:0009603)1.75701109
130Aplastic anemia (HP:0001915)1.75639880
131Bicuspid aortic valve (HP:0001647)1.75535995
132Porencephaly (HP:0002132)1.74851739
133Impulsivity (HP:0100710)1.74606042
134Abnormality of the common coagulation pathway (HP:0010990)1.74026460
135Gastrointestinal infarctions (HP:0005244)1.73906151
136Skin ulcer (HP:0200042)1.73419323
137Segmental peripheral demyelination/remyelination (HP:0003481)1.72743363
138Proximal placement of thumb (HP:0009623)1.72089517
139Increased nuchal translucency (HP:0010880)1.72070542
140Abnormality of the thoracic spine (HP:0100711)1.71272968
141Delayed epiphyseal ossification (HP:0002663)1.71162389
142Abnormality of the peritoneum (HP:0002585)1.70787099
143Fatigue (HP:0012378)1.70569897
144Bladder neoplasm (HP:0009725)1.69789587
145Bladder carcinoma (HP:0002862)1.69789587
146Abnormal number of incisors (HP:0011064)1.69399298
147Somatic mutation (HP:0001428)1.69315023
148Keratoconjunctivitis (HP:0001096)1.69009354
149Aplasia/Hypoplasia of the uvula (HP:0010293)1.68767290
150Keratoconjunctivitis sicca (HP:0001097)1.68018804
151Dislocated radial head (HP:0003083)1.67746977
152Thin bony cortex (HP:0002753)1.67376629
153Intestinal fistula (HP:0100819)1.66886813
15411 pairs of ribs (HP:0000878)1.66722643
155Prominent nose (HP:0000448)1.66038841
156Limited elbow extension (HP:0001377)1.65923304
157Supernumerary ribs (HP:0005815)1.65881870
158Premature ovarian failure (HP:0008209)1.63951888
159Aseptic necrosis (HP:0010885)1.62493108
160Viral hepatitis (HP:0006562)1.61642793
161Prolonged bleeding time (HP:0003010)1.61096005
162Gangrene (HP:0100758)1.60781018
163Metaphyseal irregularity (HP:0003025)1.60290904
164Multiple enchondromatosis (HP:0005701)1.60202293

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K13.85279740
2MAP3K103.48108644
3PRPF4B3.18314930
4SMG12.90002983
5TXK2.88310809
6JAK32.71927758
7CDK122.55995331
8MAP3K142.18286723
9TYK22.17931564
10IRAK42.11702518
11CDC72.10012641
12STK102.07037391
13ZAP701.99584892
14BLK1.93245562
15TBK11.92432466
16RPS6KA41.87059347
17MAP3K131.83614374
18EEF2K1.81885765
19BTK1.77797273
20ERN11.69472951
21NEK21.68481004
22IKBKE1.67364711
23SIK31.58732053
24CHUK1.56016936
25IKBKB1.45348960
26TAOK21.43885163
27KSR21.42214588
28TEC1.38642398
29BRD41.35177992
30ITK1.33067127
31TAOK11.29045534
32STK241.26958405
33FGFR41.25616777
34CLK11.25198467
35KIT1.24498232
36MAP3K91.21265111
37STK41.18422384
38TRIB31.18251456
39SYK1.17116486
40CDK41.16335464
41PIM11.13752483
42SIK11.13182286
43FGFR31.12703587
44LCK1.10976838
45LRRK21.10006411
46JAK11.09334033
47HCK1.08997335
48ATR1.08976613
49PKN21.08775468
50CDK61.06710672
51TYRO31.04983659
52MATK1.03782886
53TGFBR11.03437032
54PIM21.03009297
55MKNK11.01286112
56MAP3K11.00641660
57CSK0.98473852
58FGR0.97860863
59IRAK30.96638326
60PLK40.95793955
61MAPK110.93889492
62TTK0.93695886
63RIPK10.92855278
64STK30.92758682
65CSF1R0.92744210
66MAP3K80.91344846
67IRAK20.89168047
68WNK10.88781338
69PBK0.87891449
70BUB10.87780879
71LYN0.87692236
72MAP2K30.85780368
73EPHA30.84726114
74EPHB10.83578903
75PTK60.83251032
76MELK0.83032642
77CDC42BPA0.81583129
78TGFBR20.79821019
79MAP3K30.78887339
80RIPK40.78229086
81NME20.78112842
82NLK0.77208084
83JAK20.76204978
84YES10.73904240
85ALK0.73567833
86AURKB0.71747867
87MAPKAPK20.70848274
88DYRK30.70184343
89MARK30.70044264
90MAP3K110.69158796
91CDK70.68968800
92PASK0.68803374
93CDK90.65742774
94TSSK60.64880501
95SIK20.62961518
96BRAF0.62561527
97CHEK10.61876785
98TAF10.60549610
99MTOR0.59774238
100NEK90.59311041
101BRSK20.58388060
102PAK40.58088997
103SRPK10.56705458
104TESK20.55795686
105KDR0.54838555
106ERBB30.54777903
107WEE10.54511428
108DMPK0.54493578
109CAMK1D0.54122178
110MARK20.53674464
111PDGFRA0.51576536
112ACVR1B0.51074862
113TAOK30.50590672
114ATM0.50451356
115EIF2AK10.50230090
116CHEK20.49040978
117HIPK20.48856651
118EGFR0.48832487
119CAMK1G0.48764023
120MAP3K50.48141067
121CDK80.47576414
122PLK10.46920781
123FGFR10.46830904
124SGK30.45665371
125PDPK10.44807143
126KSR10.44025179
127ARAF0.43963294
128ICK0.43627651
129PDK10.42325443
130GRK60.40757548
131CDK20.40470400
132RPS6KA10.40361573
133DDR20.40217654
134IRAK10.39765447

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051402.53130471
2NF-kappa B signaling pathway_Homo sapiens_hsa040642.43860372
3DNA replication_Homo sapiens_hsa030302.35556498
4Measles_Homo sapiens_hsa051622.16212333
5Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.15041818
6Primary immunodeficiency_Homo sapiens_hsa053401.99405972
7Herpes simplex infection_Homo sapiens_hsa051681.90847627
8Osteoclast differentiation_Homo sapiens_hsa043801.81986526
9NOD-like receptor signaling pathway_Homo sapiens_hsa046211.81953284
10Toll-like receptor signaling pathway_Homo sapiens_hsa046201.81001803
11Allograft rejection_Homo sapiens_hsa053301.80337868
12Asthma_Homo sapiens_hsa053101.78291685
13Graft-versus-host disease_Homo sapiens_hsa053321.75026070
14Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.70078045
15Legionellosis_Homo sapiens_hsa051341.69453723
16Intestinal immune network for IgA production_Homo sapiens_hsa046721.67219432
17RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.65688691
18B cell receptor signaling pathway_Homo sapiens_hsa046621.64427224
19Base excision repair_Homo sapiens_hsa034101.62969829
20T cell receptor signaling pathway_Homo sapiens_hsa046601.62234506
21Antigen processing and presentation_Homo sapiens_hsa046121.59631490
22Cell cycle_Homo sapiens_hsa041101.58585439
23Hematopoietic cell lineage_Homo sapiens_hsa046401.54873974
24TNF signaling pathway_Homo sapiens_hsa046681.52460938
25Jak-STAT signaling pathway_Homo sapiens_hsa046301.50238708
26Influenza A_Homo sapiens_hsa051641.49299185
27Chronic myeloid leukemia_Homo sapiens_hsa052201.48783500
28Spliceosome_Homo sapiens_hsa030401.48207620
29Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.45229953
30Hepatitis B_Homo sapiens_hsa051611.42996311
31Toxoplasmosis_Homo sapiens_hsa051451.42675034
32Viral myocarditis_Homo sapiens_hsa054161.42626703
33Mismatch repair_Homo sapiens_hsa034301.41300441
34Bladder cancer_Homo sapiens_hsa052191.38458917
35Pertussis_Homo sapiens_hsa051331.28251264
36Apoptosis_Homo sapiens_hsa042101.27255459
37Shigellosis_Homo sapiens_hsa051311.26683438
38Tuberculosis_Homo sapiens_hsa051521.22833728
39Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.22299184
40Homologous recombination_Homo sapiens_hsa034401.22282057
41Endometrial cancer_Homo sapiens_hsa052131.22011665
42HTLV-I infection_Homo sapiens_hsa051661.21224639
43Acute myeloid leukemia_Homo sapiens_hsa052211.20772295
44Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.20387561
45Malaria_Homo sapiens_hsa051441.17979317
46Epstein-Barr virus infection_Homo sapiens_hsa051691.16425700
47RNA transport_Homo sapiens_hsa030131.16099157
48Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.15356345
49Type I diabetes mellitus_Homo sapiens_hsa049401.13713362
50Chemokine signaling pathway_Homo sapiens_hsa040621.10645329
51Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.09841908
52Transcriptional misregulation in cancer_Homo sapiens_hsa052021.08963763
53Small cell lung cancer_Homo sapiens_hsa052221.07070997
54Viral carcinogenesis_Homo sapiens_hsa052031.06775996
55Staphylococcus aureus infection_Homo sapiens_hsa051501.06341197
56Non-homologous end-joining_Homo sapiens_hsa034501.05423731
57Pancreatic cancer_Homo sapiens_hsa052121.05091064
58AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.00607434
59MicroRNAs in cancer_Homo sapiens_hsa052060.99437265
60Autoimmune thyroid disease_Homo sapiens_hsa053200.98799406
61p53 signaling pathway_Homo sapiens_hsa041150.98071317
62Notch signaling pathway_Homo sapiens_hsa043300.96597626
63Central carbon metabolism in cancer_Homo sapiens_hsa052300.96498379
64One carbon pool by folate_Homo sapiens_hsa006700.96050718
65Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.95576072
66Fanconi anemia pathway_Homo sapiens_hsa034600.92708306
67Leukocyte transendothelial migration_Homo sapiens_hsa046700.92497205
68Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.92021414
69Salmonella infection_Homo sapiens_hsa051320.90844615
70mRNA surveillance pathway_Homo sapiens_hsa030150.88850046
71Hepatitis C_Homo sapiens_hsa051600.86425499
72Thyroid hormone signaling pathway_Homo sapiens_hsa049190.85773841
73Ribosome_Homo sapiens_hsa030100.84197798
74Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.82454394
75Prolactin signaling pathway_Homo sapiens_hsa049170.81341727
76RNA degradation_Homo sapiens_hsa030180.81314073
77Neurotrophin signaling pathway_Homo sapiens_hsa047220.78958944
78Fructose and mannose metabolism_Homo sapiens_hsa000510.78192863
79Other glycan degradation_Homo sapiens_hsa005110.77645303
80ErbB signaling pathway_Homo sapiens_hsa040120.71914475
81Adipocytokine signaling pathway_Homo sapiens_hsa049200.71905540
82Colorectal cancer_Homo sapiens_hsa052100.69316963
83Nucleotide excision repair_Homo sapiens_hsa034200.68525973
84Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.66956576
85Insulin signaling pathway_Homo sapiens_hsa049100.66807202
86Non-small cell lung cancer_Homo sapiens_hsa052230.65674074
87Glycosaminoglycan degradation_Homo sapiens_hsa005310.65566578
88Longevity regulating pathway - mammal_Homo sapiens_hsa042110.64662028
89HIF-1 signaling pathway_Homo sapiens_hsa040660.62644147
90Pyrimidine metabolism_Homo sapiens_hsa002400.61656250
91Prion diseases_Homo sapiens_hsa050200.59820350
92Inositol phosphate metabolism_Homo sapiens_hsa005620.57254399
93Platelet activation_Homo sapiens_hsa046110.57189348
94Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.57137934
95Adherens junction_Homo sapiens_hsa045200.54830020
96VEGF signaling pathway_Homo sapiens_hsa043700.54487317
97Prostate cancer_Homo sapiens_hsa052150.53683617
98Proteoglycans in cancer_Homo sapiens_hsa052050.53145684
99Glioma_Homo sapiens_hsa052140.52690725
100Rheumatoid arthritis_Homo sapiens_hsa053230.51910148
101Choline metabolism in cancer_Homo sapiens_hsa052310.51273894
102Dorso-ventral axis formation_Homo sapiens_hsa043200.50542048
103Phosphatidylinositol signaling system_Homo sapiens_hsa040700.50064528
104Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.49200133
105Systemic lupus erythematosus_Homo sapiens_hsa053220.48963557
106Pathways in cancer_Homo sapiens_hsa052000.48876934
107Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.48225890
108Lysine degradation_Homo sapiens_hsa003100.46103675
109mTOR signaling pathway_Homo sapiens_hsa041500.45709523
110Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.45461494
111FoxO signaling pathway_Homo sapiens_hsa040680.45086952
112Thyroid cancer_Homo sapiens_hsa052160.43984158
113Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.42228093
114African trypanosomiasis_Homo sapiens_hsa051430.41077806
115Renal cell carcinoma_Homo sapiens_hsa052110.37515337
116Insulin resistance_Homo sapiens_hsa049310.36944439
117Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.35999793

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