PHAX

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit biogenesis (GO:0042274)4.94273885
2cullin deneddylation (GO:0010388)4.90243988
3mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.84190131
4maturation of SSU-rRNA (GO:0030490)4.82928460
5proteasome assembly (GO:0043248)4.80557370
6viral transcription (GO:0019083)4.66474697
7translational termination (GO:0006415)4.59557701
8protein deneddylation (GO:0000338)4.58294348
9energy coupled proton transport, down electrochemical gradient (GO:0015985)4.58105276
10ATP synthesis coupled proton transport (GO:0015986)4.58105276
11protein neddylation (GO:0045116)4.49125169
12transcription elongation from RNA polymerase III promoter (GO:0006385)4.44991154
13termination of RNA polymerase III transcription (GO:0006386)4.44991154
14negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.37582735
15ribosomal large subunit biogenesis (GO:0042273)4.28823192
16establishment of protein localization to mitochondrial membrane (GO:0090151)4.25495540
17RNA capping (GO:0036260)4.22339540
187-methylguanosine RNA capping (GO:0009452)4.22339540
197-methylguanosine mRNA capping (GO:0006370)4.21082788
20ribosomal small subunit assembly (GO:0000028)4.19254037
21cotranslational protein targeting to membrane (GO:0006613)4.09079878
22SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.08345324
23positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.06606184
24negative regulation of ubiquitin-protein transferase activity (GO:0051444)4.01399841
25negative regulation of ligase activity (GO:0051352)4.01399841
26formation of translation preinitiation complex (GO:0001731)4.00991486
27chaperone-mediated protein transport (GO:0072321)4.00916597
28protein targeting to ER (GO:0045047)4.00900530
29regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.95772776
30translational elongation (GO:0006414)3.93727649
31establishment of integrated proviral latency (GO:0075713)3.91686047
32translational initiation (GO:0006413)3.90480525
33anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.88005895
34protein localization to endoplasmic reticulum (GO:0070972)3.87185426
35* spliceosomal snRNP assembly (GO:0000387)3.87171163
36cellular protein complex disassembly (GO:0043624)3.84723065
37DNA double-strand break processing (GO:0000729)3.84694756
38DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.82937846
39ribonucleoprotein complex biogenesis (GO:0022613)3.80947549
40establishment of protein localization to endoplasmic reticulum (GO:0072599)3.78809450
41intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.76916240
42signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.76916240
43signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.73934519
44signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.73934519
45signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.73934519
46mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.70841488
47viral life cycle (GO:0019058)3.68163411
48GTP biosynthetic process (GO:0006183)3.67741678
49translation (GO:0006412)3.67439869
50DNA damage response, detection of DNA damage (GO:0042769)3.66707419
51regulation of cellular amino acid metabolic process (GO:0006521)3.65446282
52signal transduction involved in DNA integrity checkpoint (GO:0072401)3.65364323
53signal transduction involved in DNA damage checkpoint (GO:0072422)3.65364323
54water-soluble vitamin biosynthetic process (GO:0042364)3.63548802
55signal transduction involved in cell cycle checkpoint (GO:0072395)3.61813455
56nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.61779262
57rRNA processing (GO:0006364)3.59488344
58respiratory chain complex IV assembly (GO:0008535)3.58741318
59rRNA modification (GO:0000154)3.58675010
60nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.56280666
61establishment of viral latency (GO:0019043)3.53826287
62positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.53210931
63negative regulation of DNA-dependent DNA replication (GO:2000104)3.53020882
64CENP-A containing nucleosome assembly (GO:0034080)3.52182540
65spliceosomal complex assembly (GO:0000245)3.51830358
66maturation of 5.8S rRNA (GO:0000460)3.51037073
67exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.50452020
68pseudouridine synthesis (GO:0001522)3.50438483
69DNA strand elongation involved in DNA replication (GO:0006271)3.50037391
70guanosine-containing compound biosynthetic process (GO:1901070)3.45970010
71rRNA metabolic process (GO:0016072)3.44709978
72cellular component biogenesis (GO:0044085)3.44286943
73chromatin remodeling at centromere (GO:0031055)3.42542301
74transcription elongation from RNA polymerase I promoter (GO:0006362)3.41586808
75transcription-coupled nucleotide-excision repair (GO:0006283)3.40244280
76positive regulation of ligase activity (GO:0051351)3.38388057
77purine nucleobase biosynthetic process (GO:0009113)3.36639557
78UTP biosynthetic process (GO:0006228)3.35289175
79nucleobase biosynthetic process (GO:0046112)3.35087969
80transcription from RNA polymerase I promoter (GO:0006360)3.33002053
81DNA strand elongation (GO:0022616)3.32996377
82somatic diversification of immune receptors via somatic mutation (GO:0002566)3.32835881
83somatic hypermutation of immunoglobulin genes (GO:0016446)3.32835881
84DNA replication checkpoint (GO:0000076)3.31991654
85protein complex disassembly (GO:0043241)3.31596130
86telomere maintenance via semi-conservative replication (GO:0032201)3.31140485
87antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.31122834
88protein complex biogenesis (GO:0070271)3.25720086
89macromolecular complex disassembly (GO:0032984)3.25547339
90replication fork processing (GO:0031297)3.22980968
91termination of RNA polymerase I transcription (GO:0006363)3.22364547
92histone exchange (GO:0043486)3.22159491
93L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.21441177
94establishment of protein localization to mitochondrion (GO:0072655)3.20729678
95tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.16564588
96RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.16564588
97respiratory electron transport chain (GO:0022904)3.15942621
98mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.15245760
99mitochondrial respiratory chain complex I assembly (GO:0032981)3.15245760
100NADH dehydrogenase complex assembly (GO:0010257)3.15245760
101regulation of ubiquitin-protein transferase activity (GO:0051438)3.15233824
102protein targeting to mitochondrion (GO:0006626)3.15178854
103ribosome biogenesis (GO:0042254)3.15046935
104regulation of nuclear cell cycle DNA replication (GO:0033262)3.13672138
105regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.11902487
106regulation of mitotic spindle checkpoint (GO:1903504)3.11902487
107regulation of mitochondrial translation (GO:0070129)3.11106387
108viral mRNA export from host cell nucleus (GO:0046784)3.10767679
109cytochrome complex assembly (GO:0017004)3.10767357
110regulation of DNA endoreduplication (GO:0032875)3.09881990
111mitochondrial respiratory chain complex assembly (GO:0033108)3.08373958
112protein K6-linked ubiquitination (GO:0085020)3.08324019
113protein-cofactor linkage (GO:0018065)3.06943227
114electron transport chain (GO:0022900)3.06889336
115transcription elongation from RNA polymerase II promoter (GO:0006368)3.05775116
116telomere maintenance via recombination (GO:0000722)3.05537904
117regulation of ligase activity (GO:0051340)3.04439738
118DNA catabolic process, exonucleolytic (GO:0000738)2.99273072
119mitotic metaphase plate congression (GO:0007080)2.96931258
120behavioral response to nicotine (GO:0035095)2.95762873
121regulation of helicase activity (GO:0051095)2.86477572
122somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.80420906
123somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.80420906
124isotype switching (GO:0045190)2.80420906
125mitochondrial RNA metabolic process (GO:0000959)2.79185911
126tRNA processing (GO:0008033)2.79134547
127metaphase plate congression (GO:0051310)2.73879028
128maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.70758359
129protein localization to kinetochore (GO:0034501)2.68702671
130histone mRNA metabolic process (GO:0008334)2.68072394
131DNA replication-independent nucleosome assembly (GO:0006336)2.66100462
132DNA replication-independent nucleosome organization (GO:0034724)2.66100462
133intracellular protein transmembrane import (GO:0044743)2.63829569
134RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.62621548
135protein localization to mitochondrion (GO:0070585)2.62330196
136tRNA metabolic process (GO:0006399)2.61967265
137rRNA methylation (GO:0031167)2.59492369
138telomere maintenance via telomerase (GO:0007004)2.58751037
139DNA deamination (GO:0045006)2.58352254
140peptidyl-histidine modification (GO:0018202)2.57279598
141negative regulation of DNA recombination (GO:0045910)2.57163877
142recombinational repair (GO:0000725)2.56812888
143centriole replication (GO:0007099)2.56684967
144postreplication repair (GO:0006301)2.55365978
145double-strand break repair via homologous recombination (GO:0000724)2.53967755
146kinetochore organization (GO:0051383)2.51883743
147platelet dense granule organization (GO:0060155)2.51089858
148kinetochore assembly (GO:0051382)2.50116580
149regulation of meiosis I (GO:0060631)2.48699900

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.85938868
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.40204087
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.28843818
4E2F7_22180533_ChIP-Seq_HELA_Human4.22059900
5EST1_17652178_ChIP-ChIP_JURKAT_Human4.15396592
6* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.73450227
7ETS1_20019798_ChIP-Seq_JURKAT_Human3.66138852
8HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.63894272
9CREB1_15753290_ChIP-ChIP_HEK293T_Human3.44537499
10E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.43154389
11SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.32768459
12CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.26415522
13* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.13493553
14MYC_19079543_ChIP-ChIP_MESCs_Mouse2.95001261
15ZNF274_21170338_ChIP-Seq_K562_Hela2.93660026
16EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.91661698
17MYC_18358816_ChIP-ChIP_MESCs_Mouse2.87086287
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.87072959
19MYC_19030024_ChIP-ChIP_MESCs_Mouse2.86109143
20E2F4_17652178_ChIP-ChIP_JURKAT_Human2.69462205
21VDR_23849224_ChIP-Seq_CD4+_Human2.63916783
22THAP11_20581084_ChIP-Seq_MESCs_Mouse2.56413832
23XRN2_22483619_ChIP-Seq_HELA_Human2.52506490
24SALL1_21062744_ChIP-ChIP_HESCs_Human2.51739264
25CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.45096453
26ELK1_19687146_ChIP-ChIP_HELA_Human2.43745358
27DCP1A_22483619_ChIP-Seq_HELA_Human2.43416675
28HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.34976027
29FOXP3_21729870_ChIP-Seq_TREG_Human2.23937158
30ELF1_17652178_ChIP-ChIP_JURKAT_Human2.23744630
31E2F1_18555785_ChIP-Seq_MESCs_Mouse2.22958069
32TTF2_22483619_ChIP-Seq_HELA_Human2.22278115
33NELFA_20434984_ChIP-Seq_ESCs_Mouse2.16957672
34PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.15519239
35VDR_22108803_ChIP-Seq_LS180_Human2.12118692
36ZFP42_18358816_ChIP-ChIP_MESCs_Mouse2.02665943
37FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.01807831
38SRF_21415370_ChIP-Seq_HL-1_Mouse1.98459937
39YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.98213871
40GABP_19822575_ChIP-Seq_HepG2_Human1.95399092
41FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.94431035
42YY1_21170310_ChIP-Seq_MESCs_Mouse1.93197408
43GBX2_23144817_ChIP-Seq_PC3_Human1.90218024
44POU3F2_20337985_ChIP-ChIP_501MEL_Human1.87302971
45ZFP57_27257070_Chip-Seq_ESCs_Mouse1.84420248
46POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.79886230
47MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.79063439
48FLI1_27457419_Chip-Seq_LIVER_Mouse1.74521798
49GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.74401672
50MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.68837261
51IGF1R_20145208_ChIP-Seq_DFB_Human1.67510587
52PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.64989214
53MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.62836934
54TAF15_26573619_Chip-Seq_HEK293_Human1.62800724
55MYCN_18555785_ChIP-Seq_MESCs_Mouse1.61556460
56HOXB4_20404135_ChIP-ChIP_EML_Mouse1.60304151
57P300_19829295_ChIP-Seq_ESCs_Human1.57361681
58ELK1_22589737_ChIP-Seq_MCF10A_Human1.51784347
59* MYC_18940864_ChIP-ChIP_HL60_Human1.50524712
60RBPJ_22232070_ChIP-Seq_NCS_Mouse1.50273253
61TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.49996969
62CTBP2_25329375_ChIP-Seq_LNCAP_Human1.47879200
63NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.46766731
64CTBP1_25329375_ChIP-Seq_LNCAP_Human1.45814291
65FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.43249413
66POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.41856383
67GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.40950957
68KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.40239445
69SOX2_18555785_ChIP-Seq_MESCs_Mouse1.36326306
70NANOG_18555785_ChIP-Seq_MESCs_Mouse1.35334174
71POU5F1_16153702_ChIP-ChIP_HESCs_Human1.34901388
72CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.34158786
73AR_21909140_ChIP-Seq_LNCAP_Human1.34076987
74PADI4_21655091_ChIP-ChIP_MCF-7_Human1.32467983
75IRF1_19129219_ChIP-ChIP_H3396_Human1.32058112
76ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.31957946
77PCGF2_27294783_Chip-Seq_ESCs_Mouse1.31336380
78MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.27257455
79ZFX_18555785_ChIP-Seq_MESCs_Mouse1.26326313
80KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.24296896
81CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.18501045
82* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.16543708
83CIITA_25753668_ChIP-Seq_RAJI_Human1.16019798
84TP63_19390658_ChIP-ChIP_HaCaT_Human1.15564095
85KDM5A_27292631_Chip-Seq_BREAST_Human1.14147559
86CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.14035553
87EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.13112324
88ER_23166858_ChIP-Seq_MCF-7_Human1.12650110
89SOX17_20123909_ChIP-Seq_XEN_Mouse1.08844643
90DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.08648695
91BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.08617349
92FUS_26573619_Chip-Seq_HEK293_Human1.08450377
93TP53_22573176_ChIP-Seq_HFKS_Human1.07348936
94GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.04320429
95* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.03190818
96TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.02949427
97UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02722756
98AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.00781923
99RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.99190816
100PIAS1_25552417_ChIP-Seq_VCAP_Human0.98584426
101EZH2_22144423_ChIP-Seq_EOC_Human0.98177545
102SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.97061938
103SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.96682714
104CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.96263122
105* SOX2_16153702_ChIP-ChIP_HESCs_Human0.95727155
106MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.95708051
107IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.94770164
108CBP_20019798_ChIP-Seq_JUKART_Human0.94770164
109CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.94383296
110FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.94310428
111BMI1_23680149_ChIP-Seq_NPCS_Mouse0.93958565
112E2F1_21310950_ChIP-Seq_MCF-7_Human0.92595568
113SOX2_19829295_ChIP-Seq_ESCs_Human0.91738898
114NANOG_19829295_ChIP-Seq_ESCs_Human0.91738898
115SUZ12_27294783_Chip-Seq_NPCs_Mouse0.91027648
116TOP2B_26459242_ChIP-Seq_MCF-7_Human0.90419319
117KLF5_20875108_ChIP-Seq_MESCs_Mouse0.90023514
118EZH2_27294783_Chip-Seq_NPCs_Mouse0.90000140
119CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.88425834
120EWS_26573619_Chip-Seq_HEK293_Human0.87833533
121SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.87640983
122FOXM1_23109430_ChIP-Seq_U2OS_Human0.85792766
123POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.85646667
124TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.85555943
125E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.84735499
126NANOG_16153702_ChIP-ChIP_HESCs_Human0.84388174
127CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.83622306
128OCT4_18692474_ChIP-Seq_MEFs_Mouse0.76636717
129NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.76020601
130FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.74241379
131SOX2_18692474_ChIP-Seq_MEFs_Mouse0.73938950
132* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.73273373
133REST_19997604_ChIP-ChIP_NEURONS_Mouse0.71860589
134SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.68700688
135CTCF_18555785_ChIP-Seq_MESCs_Mouse0.66526066
136NOTCH1_21737748_ChIP-Seq_TLL_Human0.65283921
137* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.63984456
138* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.63265373
139TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.62753294

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode4.01949629
2MP0003123_paternal_imprinting3.65610212
3MP0004957_abnormal_blastocyst_morpholog3.06581519
4MP0009379_abnormal_foot_pigmentation2.96620753
5MP0003880_abnormal_central_pattern2.96288372
6MP0001529_abnormal_vocalization2.89708584
7MP0003693_abnormal_embryo_hatching2.81269010
8MP0008057_abnormal_DNA_replication2.76737078
9MP0010094_abnormal_chromosome_stability2.49710732
10MP0008058_abnormal_DNA_repair2.44400368
11MP0008932_abnormal_embryonic_tissue2.44088357
12MP0003077_abnormal_cell_cycle2.28529611
13MP0009697_abnormal_copulation2.26125005
14MP0003121_genomic_imprinting2.23534728
15MP0003718_maternal_effect2.21809224
16MP0003890_abnormal_embryonic-extraembry2.14088364
17MP0002638_abnormal_pupillary_reflex2.11785767
18MP0001905_abnormal_dopamine_level2.04092101
19MP0010030_abnormal_orbit_morphology1.98716525
20MP0003111_abnormal_nucleus_morphology1.95427851
21MP0006276_abnormal_autonomic_nervous1.91229679
22MP0003122_maternal_imprinting1.90153750
23MP0002163_abnormal_gland_morphology1.87214367
24MP0003315_abnormal_perineum_morphology1.85101512
25MP0002751_abnormal_autonomic_nervous1.77880408
26MP0003136_yellow_coat_color1.77458173
27MP0008877_abnormal_DNA_methylation1.74317422
28MP0001188_hyperpigmentation1.66353150
29MP0003786_premature_aging1.65528671
30MP0005423_abnormal_somatic_nervous1.65320723
31MP0006072_abnormal_retinal_apoptosis1.64230617
32MP0008007_abnormal_cellular_replicative1.59312981
33MP0009046_muscle_twitch1.53374872
34MP0004133_heterotaxia1.51763778
35MP0003806_abnormal_nucleotide_metabolis1.47852180
36MP0003941_abnormal_skin_development1.46558635
37MP0001986_abnormal_taste_sensitivity1.42084680
38MP0000569_abnormal_digit_pigmentation1.41867566
39MP0003195_calcinosis1.39857975
40MP0008789_abnormal_olfactory_epithelium1.38948313
41MP0000778_abnormal_nervous_system1.38312856
42MP0002938_white_spotting1.37377070
43MP0002160_abnormal_reproductive_system1.33483566
44MP0004215_abnormal_myocardial_fiber1.33201208
45MP0000566_synostosis1.31621644
46MP0000631_abnormal_neuroendocrine_gland1.28488305
47MP0005408_hypopigmentation1.27700459
48MP0001346_abnormal_lacrimal_gland1.25769461
49MP0000427_abnormal_hair_cycle1.25156517
50MP0002102_abnormal_ear_morphology1.24031196
51MP0003186_abnormal_redox_activity1.23541116
52MP0001984_abnormal_olfaction1.21823021
53MP0002734_abnormal_mechanical_nocicepti1.21490717
54MP0003011_delayed_dark_adaptation1.18731439
55MP0000647_abnormal_sebaceous_gland1.17320813
56MP0001730_embryonic_growth_arrest1.15268153
57MP0005389_reproductive_system_phenotype1.12905194
58MP0002837_dystrophic_cardiac_calcinosis1.11505588
59MP0008872_abnormal_physiological_respon1.11263776
60MP0002234_abnormal_pharynx_morphology1.11117346
61MP0005645_abnormal_hypothalamus_physiol1.10851825
62MP0005084_abnormal_gallbladder_morpholo1.10396668
63MP0010386_abnormal_urinary_bladder1.10240997
64MP0002282_abnormal_trachea_morphology1.05639054
65MP0005551_abnormal_eye_electrophysiolog1.04613086
66MP0004381_abnormal_hair_follicle1.03544879
67MP0002736_abnormal_nociception_after1.03096663
68MP0001486_abnormal_startle_reflex1.02811084
69MP0004147_increased_porphyrin_level0.98929170
70MP0001968_abnormal_touch/_nociception0.98088086
71MP0005187_abnormal_penis_morphology0.97594752
72MP0008875_abnormal_xenobiotic_pharmacok0.97117834
73MP0000049_abnormal_middle_ear0.97049754
74MP0000372_irregular_coat_pigmentation0.97034716
75MP0001929_abnormal_gametogenesis0.96490297
76MP0004142_abnormal_muscle_tone0.96469424
77MP0000350_abnormal_cell_proliferation0.96424615
78MP0004270_analgesia0.95841125
79MP0002210_abnormal_sex_determination0.95550985
80MP0003119_abnormal_digestive_system0.94761611
81MP0003938_abnormal_ear_development0.94611607
82MP0002184_abnormal_innervation0.94495822
83MP0005174_abnormal_tail_pigmentation0.94079710
84MP0005499_abnormal_olfactory_system0.93822758
85MP0005394_taste/olfaction_phenotype0.93822758
86MP0005379_endocrine/exocrine_gland_phen0.91985203
87MP0001697_abnormal_embryo_size0.91876513
88MP0003937_abnormal_limbs/digits/tail_de0.90634683
89MP0005253_abnormal_eye_physiology0.90063147
90MP0002233_abnormal_nose_morphology0.90022401
91MP0001286_abnormal_eye_development0.89836829
92MP0008260_abnormal_autophagy0.88592881
93MP0002735_abnormal_chemical_nociception0.87087721
94MP0003755_abnormal_palate_morphology0.86168208
95MP0001919_abnormal_reproductive_system0.85565126
96MP0002095_abnormal_skin_pigmentation0.85531952
97MP0002752_abnormal_somatic_nervous0.85231281
98MP0001485_abnormal_pinna_reflex0.84898917
99MP0008995_early_reproductive_senescence0.84842431
100MP0003646_muscle_fatigue0.84135399
101MP0002277_abnormal_respiratory_mucosa0.83983783
102MP0003878_abnormal_ear_physiology0.83584762
103MP0005377_hearing/vestibular/ear_phenot0.83584762
104MP0003137_abnormal_impulse_conducting0.83006593
105MP0002572_abnormal_emotion/affect_behav0.82125913
106MP0002272_abnormal_nervous_system0.82083986
107MP0005195_abnormal_posterior_eye0.82027681
108MP0000026_abnormal_inner_ear0.81752903
109MP0006035_abnormal_mitochondrial_morpho0.81265968
110MP0001299_abnormal_eye_distance/0.81243356
111MP0001727_abnormal_embryo_implantation0.80542321
112MP0005075_abnormal_melanosome_morpholog0.80197128
113MP0002064_seizures0.80125660
114MP0001145_abnormal_male_reproductive0.79841261
115MP0003861_abnormal_nervous_system0.79655573
116MP0002653_abnormal_ependyma_morphology0.79650646
117MP0001293_anophthalmia0.77641800
118MP0002085_abnormal_embryonic_tissue0.74720888
119MP0009250_abnormal_appendicular_skeleto0.73802154
120MP0009745_abnormal_behavioral_response0.72901811
121MP0005380_embryogenesis_phenotype0.72531053
122MP0001672_abnormal_embryogenesis/_devel0.72531053
123MP0003567_abnormal_fetal_cardiomyocyte0.72032130
124MP0000537_abnormal_urethra_morphology0.71172134
125MP0003787_abnormal_imprinting0.71115845
126MP0006036_abnormal_mitochondrial_physio0.70505159
127MP0000653_abnormal_sex_gland0.70388837
128MP0001970_abnormal_pain_threshold0.69057964
129MP0002080_prenatal_lethality0.68685508
130MP0005409_darkened_coat_color0.68353188
131MP0002882_abnormal_neuron_morphology0.67930802
132MP0002067_abnormal_sensory_capabilities0.67741841
133MP0005171_absent_coat_pigmentation0.67391732

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.01448825
2Abnormal mitochondria in muscle tissue (HP:0008316)4.33108221
3Mitochondrial inheritance (HP:0001427)4.29036826
4Progressive macrocephaly (HP:0004481)4.08680091
5Increased serum pyruvate (HP:0003542)3.93300912
6Abnormality of glycolysis (HP:0004366)3.93300912
7Birth length less than 3rd percentile (HP:0003561)3.91778387
8Acute encephalopathy (HP:0006846)3.75856294
9Increased CSF lactate (HP:0002490)3.69339812
10Breast hypoplasia (HP:0003187)3.63615989
11Cerebral hypomyelination (HP:0006808)3.62552938
12Hepatocellular necrosis (HP:0001404)3.55368441
13Increased hepatocellular lipid droplets (HP:0006565)3.42096052
14Abnormality of cells of the erythroid lineage (HP:0012130)3.27353903
15Macrocytic anemia (HP:0001972)3.26099377
16Molar tooth sign on MRI (HP:0002419)3.08624801
17Abnormality of midbrain morphology (HP:0002418)3.08624801
18Reticulocytopenia (HP:0001896)3.03832196
193-Methylglutaconic aciduria (HP:0003535)3.03006617
20Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.95357474
21Abnormality of the labia minora (HP:0012880)2.94791092
22Renal Fanconi syndrome (HP:0001994)2.94360870
23Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.93585839
24Methylmalonic acidemia (HP:0002912)2.88805078
25Optic disc pallor (HP:0000543)2.88195043
26Hepatic necrosis (HP:0002605)2.83912033
27Colon cancer (HP:0003003)2.80330069
28Abnormal number of erythroid precursors (HP:0012131)2.78127784
29Leukodystrophy (HP:0002415)2.77537315
30Lipid accumulation in hepatocytes (HP:0006561)2.73001141
31Increased serum lactate (HP:0002151)2.71236849
32Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.60871496
33Abnormality of alanine metabolism (HP:0010916)2.60871496
34Hyperalaninemia (HP:0003348)2.60871496
35Congenital, generalized hypertrichosis (HP:0004540)2.53329052
36Medial flaring of the eyebrow (HP:0010747)2.53112932
37Exercise intolerance (HP:0003546)2.43442810
38Nephronophthisis (HP:0000090)2.43064978
39Gait imbalance (HP:0002141)2.40432537
40Pallor (HP:0000980)2.39924592
41Congenital primary aphakia (HP:0007707)2.36284535
42Respiratory failure (HP:0002878)2.36251590
43Aplasia/Hypoplasia of the sacrum (HP:0008517)2.34644902
44Pancreatic cysts (HP:0001737)2.32122217
45Decreased activity of mitochondrial respiratory chain (HP:0008972)2.31747020
46Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.31747020
47Methylmalonic aciduria (HP:0012120)2.31457636
48Patellar aplasia (HP:0006443)2.31139518
49Pancreatic fibrosis (HP:0100732)2.30327478
50Nephrogenic diabetes insipidus (HP:0009806)2.26913306
51Meckel diverticulum (HP:0002245)2.26518784
52Aplasia/Hypoplasia of the patella (HP:0006498)2.24634129
53Postnatal microcephaly (HP:0005484)2.24588747
54Progressive inability to walk (HP:0002505)2.22029712
55CNS hypomyelination (HP:0003429)2.21700412
56True hermaphroditism (HP:0010459)2.21206451
57Supernumerary spleens (HP:0009799)2.20931811
58Triphalangeal thumb (HP:0001199)2.20078298
59Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.20044536
60Cerebral edema (HP:0002181)2.19037263
61Abnormality of the ileum (HP:0001549)2.18716278
62Abnormality of the preputium (HP:0100587)2.16125502
63Septo-optic dysplasia (HP:0100842)2.15498925
64Oral leukoplakia (HP:0002745)2.15028051
65Abnormality of the hip-girdle musculature (HP:0001445)2.13916883
66Abnormality of the musculature of the pelvis (HP:0001469)2.13916883
67Volvulus (HP:0002580)2.13048298
68Abnormal lung lobation (HP:0002101)2.12939130
69Respiratory difficulties (HP:0002880)2.12192383
70Congenital stationary night blindness (HP:0007642)2.11964356
71Ependymoma (HP:0002888)2.08174549
72Aplastic anemia (HP:0001915)2.07370234
73Inability to walk (HP:0002540)2.06775263
74Lactic acidosis (HP:0003128)2.06415261
75Sclerocornea (HP:0000647)2.05948451
76Absent radius (HP:0003974)2.03922913
77Exertional dyspnea (HP:0002875)2.02639951
78Abnormality of serum amino acid levels (HP:0003112)2.02445846
79Carpal bone hypoplasia (HP:0001498)1.99730425
80Hypoplasia of the pons (HP:0012110)1.99694075
81Renal cortical cysts (HP:0000803)1.98771705
82Abnormality of the renal cortex (HP:0011035)1.98206925
83Aplasia/Hypoplasia of the tibia (HP:0005772)1.97518289
84Progressive external ophthalmoplegia (HP:0000590)1.97476258
85Hyperventilation (HP:0002883)1.97265344
86Abnormality of the pons (HP:0007361)1.96676025
87Rough bone trabeculation (HP:0100670)1.96430605
88Horseshoe kidney (HP:0000085)1.95541048
89Aplasia/hypoplasia of the uterus (HP:0008684)1.93501549
90Aplasia/Hypoplasia of the uvula (HP:0010293)1.93254834
91Irregular epiphyses (HP:0010582)1.92859183
92Lissencephaly (HP:0001339)1.92370388
93Abnormality of the septum pellucidum (HP:0007375)1.91927515
94Vaginal atresia (HP:0000148)1.91637132
95Absent forearm bone (HP:0003953)1.91240965
96Aplasia involving forearm bones (HP:0009822)1.91240965
97Abnormality of the renal medulla (HP:0100957)1.90837266
98Pendular nystagmus (HP:0012043)1.90505904
99Aplasia/Hypoplasia of the tongue (HP:0010295)1.90206947
100Type II lissencephaly (HP:0007260)1.89840038
101Chromsome breakage (HP:0040012)1.89518605
102Glioma (HP:0009733)1.88675207
103Small hand (HP:0200055)1.86602611
104Genital tract atresia (HP:0001827)1.86141864
105Abnormality of methionine metabolism (HP:0010901)1.86136614
106Stenosis of the external auditory canal (HP:0000402)1.85201135
107Hyperglycinemia (HP:0002154)1.84255079
108Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.83979025
109Emotional lability (HP:0000712)1.83506682
110Abnormal number of incisors (HP:0011064)1.82796628
111Short tibia (HP:0005736)1.81734689
112Lethargy (HP:0001254)1.81182449
113Adrenal hypoplasia (HP:0000835)1.81162619
114Bilateral microphthalmos (HP:0007633)1.81159485
115Chromosomal breakage induced by crosslinking agents (HP:0003221)1.79399396
116Male pseudohermaphroditism (HP:0000037)1.78077386
117Facial cleft (HP:0002006)1.77518014
118Microvesicular hepatic steatosis (HP:0001414)1.77068455
119Optic nerve hypoplasia (HP:0000609)1.76717535
120Hypothermia (HP:0002045)1.76459688
121Abnormality of aspartate family amino acid metabolism (HP:0010899)1.74619559
122Glossoptosis (HP:0000162)1.74135938
123Delusions (HP:0000746)1.73606122
124Increased intramyocellular lipid droplets (HP:0012240)1.73413276
125Cleft eyelid (HP:0000625)1.71897966
126Sloping forehead (HP:0000340)1.71243382
127Secondary amenorrhea (HP:0000869)1.70372234
128Poor coordination (HP:0002370)1.69421833
129Unsteady gait (HP:0002317)1.69159825
130Duodenal stenosis (HP:0100867)1.68737711
131Small intestinal stenosis (HP:0012848)1.68737711
132Premature graying of hair (HP:0002216)1.68255495
133Absent septum pellucidum (HP:0001331)1.67846436
134Abnormality of chromosome stability (HP:0003220)1.67071330
135Abnormal protein N-linked glycosylation (HP:0012347)1.66232353
136Abnormal protein glycosylation (HP:0012346)1.66232353
137Abnormal glycosylation (HP:0012345)1.66232353
138Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.66232353
139Anencephaly (HP:0002323)1.65751804
140Abnormality of renal resorption (HP:0011038)1.65639406
141CNS demyelination (HP:0007305)1.65634485
142Asplenia (HP:0001746)1.65602946
143Nasolacrimal duct obstruction (HP:0000579)1.61996271
144Preaxial hand polydactyly (HP:0001177)1.61072032
145Type I transferrin isoform profile (HP:0003642)1.60893727
146Neuroendocrine neoplasm (HP:0100634)1.60205082
147Poor suck (HP:0002033)1.59275096
148X-linked dominant inheritance (HP:0001423)1.57609125

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.54699144
2STK163.89766576
3TLK13.22516181
4SRPK12.87053426
5WEE12.52233060
6NME22.47620498
7TSSK62.45214866
8MST42.42970550
9CASK2.42021492
10FRK2.39794755
11NUAK12.37349129
12EIF2AK12.34359143
13MKNK12.34152860
14TRIM282.33397125
15NME12.32159535
16MAP4K22.27868159
17VRK22.26411523
18PBK2.23115641
19CDC72.08758427
20TNIK1.95976984
21MKNK21.92205187
22PNCK1.91717092
23EIF2AK31.88957204
24VRK11.88119427
25BRSK21.80552484
26PLK41.76871556
27TESK21.63211617
28DYRK21.62566951
29MAP3K121.58267112
30PLK31.51830350
31BMPR1B1.50971260
32CDK81.39558921
33BCR1.39115426
34LIMK11.35215861
35ACVR1B1.20971565
36PLK11.20389144
37PDK21.18536881
38CDK71.18080420
39PLK21.17443147
40TAF11.17411980
41MAP3K41.16262389
42AURKA1.15456173
43BRAF1.09891305
44INSRR1.08939282
45CSNK1G31.04676303
46DYRK31.01999254
47ERBB31.00960057
48CDK191.00621807
49BRSK10.97978028
50MARK10.97478290
51PASK0.95280282
52ARAF0.92647573
53PAK30.90126371
54AKT30.88088356
55NEK10.87459746
56AURKB0.84250509
57OXSR10.83455977
58STK390.80837754
59TGFBR10.80419946
60ATR0.80067143
61WNK40.79923394
62MAPK130.77314610
63PHKG20.76762875
64PHKG10.76762875
65UHMK10.75638855
66CSNK2A20.74796407
67MAP2K70.73790335
68PRKCE0.72462318
69CSNK2A10.72352902
70ERBB40.70012076
71RPS6KA50.69837634
72GRK50.67593344
73CSNK1G10.66103528
74EPHA40.65426704
75CHEK20.64856289
76ATM0.64573260
77STK30.63970551
78TTK0.63458431
79CAMK2B0.62794413
80TIE10.62181888
81MYLK0.60977117
82ILK0.60389483
83PINK10.60123807
84TXK0.59874286
85CDK140.58827911
86CCNB10.58683520
87YES10.58542658
88BMPR20.56061737
89WNK30.55655009
90STK38L0.55034341
91PAK10.54029782
92PIM20.53745281
93ZAK0.52342870
94BCKDK0.52018586
95CSNK1A1L0.51576288
96RPS6KA40.51288328
97PAK40.50071706
98CDK180.48753107
99EIF2AK20.48219308
100ROCK20.48158353
101CHEK10.47641873
102CAMKK20.47495745
103TESK10.46853720
104DAPK30.45878876
105DYRK1A0.44337537
106CDK150.43753041
107CDK11A0.42935684
108MINK10.42720658
109CAMK2A0.42169496
110MUSK0.42123907
111CSNK1G20.42004706
112GRK70.41861716
113NEK20.41356010
114CSNK1E0.40929030
115ADRBK10.40750300
116PRKCI0.40454843
117PRPF4B0.39276895
118CSNK1A10.39125668
119CDK10.38675284
120ADRBK20.37785038
121CLK10.36909302
122DAPK10.36904437
123NEK60.36323782
124PRKDC0.35928684
125PRKCG0.35769695
126MAPKAPK50.33392320
127EPHA20.32828751
128CDK20.32589772
129CDK30.32034085
130ALK0.31920432
131CSNK1D0.31075952
132LATS10.30793019
133GRK10.30163509

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.81338776
2Ribosome_Homo sapiens_hsa030104.75078447
3RNA polymerase_Homo sapiens_hsa030204.24148321
4Oxidative phosphorylation_Homo sapiens_hsa001903.52811303
5DNA replication_Homo sapiens_hsa030303.22563032
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.08788322
7Parkinsons disease_Homo sapiens_hsa050123.05756736
8Spliceosome_Homo sapiens_hsa030402.99930622
9Mismatch repair_Homo sapiens_hsa034302.99323054
10Protein export_Homo sapiens_hsa030602.49614236
11Huntingtons disease_Homo sapiens_hsa050162.45758086
12* RNA transport_Homo sapiens_hsa030132.43041312
13Pyrimidine metabolism_Homo sapiens_hsa002402.36979325
14Nucleotide excision repair_Homo sapiens_hsa034202.35835319
15Homologous recombination_Homo sapiens_hsa034402.27747297
16Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.14358392
17Alzheimers disease_Homo sapiens_hsa050102.12973474
18Basal transcription factors_Homo sapiens_hsa030222.07835602
19Base excision repair_Homo sapiens_hsa034101.94789695
20RNA degradation_Homo sapiens_hsa030181.80780152
21Fanconi anemia pathway_Homo sapiens_hsa034601.68754260
22Propanoate metabolism_Homo sapiens_hsa006401.68265946
23Selenocompound metabolism_Homo sapiens_hsa004501.67290256
24Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.66890609
25Cell cycle_Homo sapiens_hsa041101.66003732
26Non-homologous end-joining_Homo sapiens_hsa034501.62700629
27Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.52769819
28Purine metabolism_Homo sapiens_hsa002301.49308584
29Phototransduction_Homo sapiens_hsa047441.41713785
30Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.36352740
31mRNA surveillance pathway_Homo sapiens_hsa030151.28081893
32Collecting duct acid secretion_Homo sapiens_hsa049661.25864442
33Butanoate metabolism_Homo sapiens_hsa006501.23676598
34One carbon pool by folate_Homo sapiens_hsa006701.22065965
35Pyruvate metabolism_Homo sapiens_hsa006201.12878478
36Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.10812766
37Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.04746663
38Tryptophan metabolism_Homo sapiens_hsa003801.01597628
39Epstein-Barr virus infection_Homo sapiens_hsa051691.00917592
40Cardiac muscle contraction_Homo sapiens_hsa042600.96435159
41Oocyte meiosis_Homo sapiens_hsa041140.95905982
42Vitamin B6 metabolism_Homo sapiens_hsa007500.91231354
43Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.86480768
44Vibrio cholerae infection_Homo sapiens_hsa051100.85785121
45Caffeine metabolism_Homo sapiens_hsa002320.83014037
46Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.82465594
47Nitrogen metabolism_Homo sapiens_hsa009100.80135947
48SNARE interactions in vesicular transport_Homo sapiens_hsa041300.79123308
49Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.77065386
50Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.75874021
51Peroxisome_Homo sapiens_hsa041460.75378982
52Maturity onset diabetes of the young_Homo sapiens_hsa049500.74860272
53Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.74552969
54Sulfur metabolism_Homo sapiens_hsa009200.72727005
55Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.72368390
56beta-Alanine metabolism_Homo sapiens_hsa004100.72135935
57Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.70686332
58Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.68875591
59Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.66997168
60Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.65277598
61Nicotine addiction_Homo sapiens_hsa050330.64474669
62Alcoholism_Homo sapiens_hsa050340.61372386
63p53 signaling pathway_Homo sapiens_hsa041150.60736545
64Regulation of autophagy_Homo sapiens_hsa041400.60722658
65Systemic lupus erythematosus_Homo sapiens_hsa053220.60574671
66Primary bile acid biosynthesis_Homo sapiens_hsa001200.57489000
67Steroid biosynthesis_Homo sapiens_hsa001000.55918032
68Chemical carcinogenesis_Homo sapiens_hsa052040.52423410
69Pentose and glucuronate interconversions_Homo sapiens_hsa000400.51965764
70Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.51797687
71Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.50414965
72Synaptic vesicle cycle_Homo sapiens_hsa047210.49552843
73Metabolic pathways_Homo sapiens_hsa011000.48351285
74Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.47266955
75Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.46668378
76Fatty acid metabolism_Homo sapiens_hsa012120.45917084
77Fatty acid elongation_Homo sapiens_hsa000620.45085108
78Serotonergic synapse_Homo sapiens_hsa047260.45049057
79Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.43625189
80Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.43349386
81Fatty acid degradation_Homo sapiens_hsa000710.42494556
82Retinol metabolism_Homo sapiens_hsa008300.41673059
83Rheumatoid arthritis_Homo sapiens_hsa053230.41249528
84Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.40983622
85Olfactory transduction_Homo sapiens_hsa047400.40816796
86Steroid hormone biosynthesis_Homo sapiens_hsa001400.38647630
87alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.38628901
88Arachidonic acid metabolism_Homo sapiens_hsa005900.35798293
89Glutathione metabolism_Homo sapiens_hsa004800.35229964
90Viral carcinogenesis_Homo sapiens_hsa052030.34681652
91Arginine and proline metabolism_Homo sapiens_hsa003300.34229465
92Phagosome_Homo sapiens_hsa041450.33713133
93Cysteine and methionine metabolism_Homo sapiens_hsa002700.33295029
94Circadian rhythm_Homo sapiens_hsa047100.30682088
95Autoimmune thyroid disease_Homo sapiens_hsa053200.30287789
96Ether lipid metabolism_Homo sapiens_hsa005650.29122106
97N-Glycan biosynthesis_Homo sapiens_hsa005100.24887033
98Folate biosynthesis_Homo sapiens_hsa007900.24844534
99Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.24066146
100Antigen processing and presentation_Homo sapiens_hsa046120.23162828
101Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.23068119
102Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.21366573
103Hedgehog signaling pathway_Homo sapiens_hsa043400.19807166
104Dopaminergic synapse_Homo sapiens_hsa047280.19158691
105Allograft rejection_Homo sapiens_hsa053300.18661208
106Asthma_Homo sapiens_hsa053100.18404530
107Axon guidance_Homo sapiens_hsa043600.17975525
108Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.17134170
109GABAergic synapse_Homo sapiens_hsa047270.16496782
110Basal cell carcinoma_Homo sapiens_hsa052170.16410279
111Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.16048717
112Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.15820801
113Linoleic acid metabolism_Homo sapiens_hsa005910.15653120
114Taste transduction_Homo sapiens_hsa047420.14776262
115Type I diabetes mellitus_Homo sapiens_hsa049400.13454140
116HTLV-I infection_Homo sapiens_hsa051660.12562290
117TGF-beta signaling pathway_Homo sapiens_hsa043500.09964865
118Morphine addiction_Homo sapiens_hsa050320.08331095
119Hippo signaling pathway_Homo sapiens_hsa043900.08120933
120Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.07174264
121Thyroid cancer_Homo sapiens_hsa052160.06434686
122Wnt signaling pathway_Homo sapiens_hsa043100.06159956
123Long-term depression_Homo sapiens_hsa047300.05825252
124Drug metabolism - other enzymes_Homo sapiens_hsa009830.05092039
125Tyrosine metabolism_Homo sapiens_hsa003500.04989059
126Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.04934143
127Viral myocarditis_Homo sapiens_hsa054160.04321799
128Sulfur relay system_Homo sapiens_hsa041220.03951902
129Amphetamine addiction_Homo sapiens_hsa050310.03602370
130Herpes simplex infection_Homo sapiens_hsa051680.03436379
131Sphingolipid metabolism_Homo sapiens_hsa006000.03171891
132Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.02708435
133Melanoma_Homo sapiens_hsa052180.02221953

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