PGLS

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)7.20361566
2viral transcription (GO:0019083)6.56080526
3translational termination (GO:0006415)6.27482249
4pyrimidine-containing compound salvage (GO:0008655)6.15031520
5pyrimidine nucleoside salvage (GO:0043097)6.15031520
6DNA deamination (GO:0045006)5.99382139
7SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.62695639
8translational elongation (GO:0006414)5.61053593
9nucleotide salvage (GO:0043173)5.55070358
10ribosomal small subunit biogenesis (GO:0042274)5.51455952
11protein targeting to ER (GO:0045047)5.46710576
12cotranslational protein targeting to membrane (GO:0006613)5.45983161
13establishment of protein localization to endoplasmic reticulum (GO:0072599)5.19269442
14protein localization to endoplasmic reticulum (GO:0070972)5.16122327
15neutrophil activation involved in immune response (GO:0002283)4.91365054
16nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.89142673
17viral life cycle (GO:0019058)4.86561968
18cellular protein complex disassembly (GO:0043624)4.78622301
19translational initiation (GO:0006413)4.69155950
20DNA strand elongation involved in DNA replication (GO:0006271)4.66559000
21maturation of SSU-rRNA (GO:0030490)4.62640496
22telomere maintenance via semi-conservative replication (GO:0032201)4.60710690
23DNA strand elongation (GO:0022616)4.41446163
24protein complex disassembly (GO:0043241)4.34480056
25macromolecular complex disassembly (GO:0032984)4.06570384
26response to peptidoglycan (GO:0032494)4.06113023
27deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.86433647
28telomere maintenance via recombination (GO:0000722)3.85427502
29ribosomal large subunit biogenesis (GO:0042273)3.84291233
30DNA unwinding involved in DNA replication (GO:0006268)3.81276366
31antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.69618593
32antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.69618593
33negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.66858049
34nuclear-transcribed mRNA catabolic process (GO:0000956)3.65128027
35protein targeting to membrane (GO:0006612)3.61023175
36translation (GO:0006412)3.60662734
37pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)3.55247266
38UMP metabolic process (GO:0046049)3.55247266
39pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)3.55247266
40UMP biosynthetic process (GO:0006222)3.55247266
41DNA replication initiation (GO:0006270)3.53652763
42mitotic recombination (GO:0006312)3.50633926
43mRNA catabolic process (GO:0006402)3.47415515
44immunoglobulin mediated immune response (GO:0016064)3.45778742
45regulation of mast cell degranulation (GO:0043304)3.44584732
46modulation by symbiont of host immune response (GO:0052553)3.43449097
47positive regulation by symbiont of host defense response (GO:0052509)3.43449097
48modulation by symbiont of host defense response (GO:0052031)3.43449097
49modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.43449097
50modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.43449097
51positive regulation by organism of defense response of other organism involved in symbiotic interact3.43449097
52formation of translation preinitiation complex (GO:0001731)3.42720103
53detection of bacterium (GO:0016045)3.39318256
54telomere maintenance via telomere lengthening (GO:0010833)3.32432107
55purine nucleotide salvage (GO:0032261)3.31707669
56RNA catabolic process (GO:0006401)3.31370005
57regulation of dendritic cell antigen processing and presentation (GO:0002604)3.31251394
58CTP biosynthetic process (GO:0006241)3.30440251
59CTP metabolic process (GO:0046036)3.30440251
60detection of other organism (GO:0098543)3.27471322
61ribonucleoprotein complex biogenesis (GO:0022613)3.26517495
62folic acid-containing compound biosynthetic process (GO:0009396)3.23474237
63nucleotide-excision repair, DNA gap filling (GO:0006297)3.20909078
64negative regulation of erythrocyte differentiation (GO:0045647)3.15708530
65antigen processing and presentation of endogenous antigen (GO:0019883)3.15561553
66purine deoxyribonucleotide catabolic process (GO:0009155)3.14783150
67pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.12344209
68neutrophil mediated immunity (GO:0002446)3.11708212
69regulation of protein heterodimerization activity (GO:0043497)3.11307656
70negative regulation of interleukin-12 production (GO:0032695)3.10959418
71positive regulation of B cell differentiation (GO:0045579)3.06442861
72Arp2/3 complex-mediated actin nucleation (GO:0034314)3.05962545
73regulation of mast cell activation involved in immune response (GO:0033006)3.05478243
74response to muramyl dipeptide (GO:0032495)3.03738212
75NIK/NF-kappaB signaling (GO:0038061)2.99399315
76amino sugar catabolic process (GO:0046348)2.96366273
77negative regulation of phagocytosis (GO:0050765)2.96207203
78respiratory burst (GO:0045730)2.92280362
79positive regulation of antigen processing and presentation (GO:0002579)2.91541660
80modulation by virus of host process (GO:0019054)2.91343857
81regulation of myeloid leukocyte mediated immunity (GO:0002886)2.90229581
82UV protection (GO:0009650)2.88643100
83negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.88162687
84negative regulation of cell killing (GO:0031342)2.88162687
85negative regulation of RNA splicing (GO:0033119)2.87914871
86pseudouridine synthesis (GO:0001522)2.87811141
87antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.86115192
88negative regulation of B cell apoptotic process (GO:0002903)2.83588122
89ncRNA 3-end processing (GO:0043628)2.83468161
90pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.82271376
91positive regulation of mast cell activation involved in immune response (GO:0033008)2.81700044
92positive regulation of mast cell degranulation (GO:0043306)2.81700044
93pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.81618097
94phosphatidylglycerol biosynthetic process (GO:0006655)2.80895336
95regulation of leukocyte degranulation (GO:0043300)2.79404393
96activation of MAPKKK activity (GO:0000185)2.78494381
97leukocyte aggregation (GO:0070486)2.75949300
98pteridine-containing compound biosynthetic process (GO:0042559)2.75586268
99negative regulation of myeloid cell apoptotic process (GO:0033033)2.74628125
100rRNA processing (GO:0006364)2.73711588
101establishment of integrated proviral latency (GO:0075713)2.73205432
102GDP-mannose metabolic process (GO:0019673)2.72776882
103positive regulation of mast cell activation (GO:0033005)2.71471705
104modulation by symbiont of host cellular process (GO:0044068)2.71198356
105regulation of antigen processing and presentation (GO:0002577)2.71161044
106neutrophil activation (GO:0042119)2.70827203
107negative regulation of interleukin-8 production (GO:0032717)2.70307752
108DNA replication checkpoint (GO:0000076)2.70109183
109cellular response to type I interferon (GO:0071357)2.69625623
110type I interferon signaling pathway (GO:0060337)2.69625623
111macrophage activation involved in immune response (GO:0002281)2.68125912
112protein localization to kinetochore (GO:0034501)2.67841430
113T cell apoptotic process (GO:0070231)2.65706934
114pinocytosis (GO:0006907)2.65262864
115regulation of superoxide anion generation (GO:0032928)2.64864923
116granulocyte activation (GO:0036230)2.64514958
117response to type I interferon (GO:0034340)2.64152767
118positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.63494366
119cellular metabolic compound salvage (GO:0043094)2.63381233
120translesion synthesis (GO:0019985)2.63206547
121positive regulation of gamma-delta T cell activation (GO:0046645)2.62603113
122rRNA metabolic process (GO:0016072)2.61637412
123detection of external biotic stimulus (GO:0098581)2.61490375
124negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.60893201
125protein maturation by protein folding (GO:0022417)2.60556400
126barbed-end actin filament capping (GO:0051016)2.58424149
127nucleoside salvage (GO:0043174)2.56621755
128nucleobase biosynthetic process (GO:0046112)2.54908794
129myeloid cell activation involved in immune response (GO:0002275)2.54026456
130cellular component biogenesis (GO:0044085)2.53964724
131positive regulation of T cell apoptotic process (GO:0070234)2.53557816
132purine-containing compound salvage (GO:0043101)2.52996706
133negative regulation of tumor necrosis factor production (GO:0032720)2.52584215
134protein retention in ER lumen (GO:0006621)2.51930519
135response to folic acid (GO:0051593)2.51498867
136antigen processing and presentation via MHC class Ib (GO:0002475)2.49721287
137antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.46670428
138protein localization to chromosome, centromeric region (GO:0071459)2.45312873
139pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.44799725
140spliceosomal snRNP assembly (GO:0000387)2.44234801
141regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.43923759
142telomere maintenance (GO:0000723)2.42177433
143pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.41711274
144telomere organization (GO:0032200)2.41201313
145establishment of protein localization to membrane (GO:0090150)2.40302084
146antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.39852394
147response to interferon-beta (GO:0035456)2.38630255
148IMP biosynthetic process (GO:0006188)2.38601014
149lymphocyte apoptotic process (GO:0070227)2.37569773
150exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.37149152
151cellular response to zinc ion (GO:0071294)2.36729113
152negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.35331286
153base-excision repair (GO:0006284)2.34068710
154pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.32436838
155protein targeting (GO:0006605)2.32180083
156pyrimidine nucleoside monophosphate metabolic process (GO:0009129)2.31173251
157nucleobase-containing small molecule interconversion (GO:0015949)2.30343318
158IMP metabolic process (GO:0046040)2.30245391
159folic acid metabolic process (GO:0046655)2.27809935
160establishment of protein localization to organelle (GO:0072594)2.27092805
161regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.26451457
162deoxyribonucleotide catabolic process (GO:0009264)2.25859969
163ribosome biogenesis (GO:0042254)2.25802725
164DNA replication-dependent nucleosome organization (GO:0034723)2.25190174
165DNA replication-dependent nucleosome assembly (GO:0006335)2.25190174
166CENP-A containing nucleosome assembly (GO:0034080)2.23657482
167activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO2.23319244
168viral mRNA export from host cell nucleus (GO:0046784)2.22672007
169metallo-sulfur cluster assembly (GO:0031163)2.22556223
170iron-sulfur cluster assembly (GO:0016226)2.22556223
171pyrimidine nucleotide catabolic process (GO:0006244)2.22555879
172oxidative phosphorylation (GO:0006119)2.22232727
173chromatin remodeling at centromere (GO:0031055)2.20694838
174nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.20439931

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.19017176
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.07072497
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.51796657
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.46639481
5* LXR_22292898_ChIP-Seq_THP-1_Human2.75547404
6SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.60405412
7MYC_22102868_ChIP-Seq_BL_Human2.54972876
8BP1_19119308_ChIP-ChIP_Hs578T_Human2.48444007
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.47482156
10FOXM1_23109430_ChIP-Seq_U2OS_Human2.39883399
11* VDR_21846776_ChIP-Seq_THP-1_Human2.37696868
12SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.33689614
13E2F4_17652178_ChIP-ChIP_JURKAT_Human2.32430993
14ELF1_17652178_ChIP-ChIP_JURKAT_Human2.30906976
15TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.26483889
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.25064275
17MYC_19079543_ChIP-ChIP_MESCs_Mouse2.24447151
18FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.20485700
19ETS1_20019798_ChIP-Seq_JURKAT_Human2.20325661
20GABP_17652178_ChIP-ChIP_JURKAT_Human2.19506667
21MYC_19030024_ChIP-ChIP_MESCs_Mouse2.17020714
22RARG_19884340_ChIP-ChIP_MEFs_Mouse2.16862881
23EST1_17652178_ChIP-ChIP_JURKAT_Human2.13172956
24KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.12372996
25XRN2_22483619_ChIP-Seq_HELA_Human2.11848379
26HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.11170888
27THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.09025077
28NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.01241771
29KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.94450349
30FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.93936714
31CREB1_15753290_ChIP-ChIP_HEK293T_Human1.90971632
32SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.89121372
33KDM2B_26808549_Chip-Seq_SUP-B15_Human1.87129890
34IRF8_22096565_ChIP-ChIP_GC-B_Human1.87089646
35VDR_23849224_ChIP-Seq_CD4+_Human1.86549281
36P68_20966046_ChIP-Seq_HELA_Human1.86086013
37BCL6_27268052_Chip-Seq_Bcells_Human1.84332800
38ELF1_20517297_ChIP-Seq_JURKAT_Human1.80969929
39NELFA_20434984_ChIP-Seq_ESCs_Mouse1.76782185
40TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.76475702
41CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.76421599
42TET1_21451524_ChIP-Seq_MESCs_Mouse1.76239489
43DCP1A_22483619_ChIP-Seq_HELA_Human1.74435295
44PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.73635055
45FOXP3_21729870_ChIP-Seq_TREG_Human1.70686890
46CIITA_25753668_ChIP-Seq_RAJI_Human1.70464638
47E2F1_18555785_ChIP-Seq_MESCs_Mouse1.70262756
48* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.69466077
49* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.65703395
50RACK7_27058665_Chip-Seq_MCF-7_Human1.65614090
51* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.65126837
52BCOR_27268052_Chip-Seq_Bcells_Human1.64994086
53SA1_27219007_Chip-Seq_ERYTHROID_Human1.64566380
54EGR1_19374776_ChIP-ChIP_THP-1_Human1.64205637
55KDM2B_26808549_Chip-Seq_DND41_Human1.63897963
56RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.62326776
57IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.59009667
58GABP_19822575_ChIP-Seq_HepG2_Human1.58459372
59SCL_19346495_ChIP-Seq_HPC-7_Human1.56556610
60HOXB4_20404135_ChIP-ChIP_EML_Mouse1.52602813
61ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.51403232
62CTCF_27219007_Chip-Seq_ERYTHROID_Human1.49647755
63TTF2_22483619_ChIP-Seq_HELA_Human1.47553581
64ZFX_18555785_ChIP-Seq_MESCs_Mouse1.47274500
65SPI1_23547873_ChIP-Seq_NB4_Human1.46128080
66FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.44092004
67CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.43722968
68CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.43276579
69SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.43211381
70CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.42929653
71E2F1_21310950_ChIP-Seq_MCF-7_Human1.41427519
72* VDR_24763502_ChIP-Seq_THP-1_Human1.39472841
73NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.39012818
74CTCF_26484167_Chip-Seq_Bcells_Mouse1.37381904
75IRF8_21731497_ChIP-ChIP_J774_Mouse1.36771309
76MYB_21317192_ChIP-Seq_ERMYB_Mouse1.35946198
77HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.35548340
78CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.34645105
79FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.33451319
80* MAF_26560356_Chip-Seq_TH1_Human1.33043416
81PU.1_20513432_ChIP-Seq_Bcells_Mouse1.32972556
82PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.32829275
83GATA1_22383799_ChIP-Seq_G1ME_Mouse1.31674963
84UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.30833877
85THAP11_20581084_ChIP-Seq_MESCs_Mouse1.30267097
86* UTX_26944678_Chip-Seq_JUKART_Human1.30247946
87SRF_21415370_ChIP-Seq_HL-1_Mouse1.29602541
88YY1_21170310_ChIP-Seq_MESCs_Mouse1.29290662
89E2F1_20622854_ChIP-Seq_HELA_Human1.28565081
90SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.26971496
91IKZF1_21737484_ChIP-ChIP_HCT116_Human1.26784124
92* SMC4_20622854_ChIP-Seq_HELA_Human1.26668851
93GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.26396398
94SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.25883798
95SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.24588599
96MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.22652576
97BRD4_27068464_Chip-Seq_AML-cells_Mouse1.22213853
98NCOR1_26117541_ChIP-Seq_K562_Human1.20854311
99PHF8_20622854_ChIP-Seq_HELA_Human1.20094546
100SA1_27219007_Chip-Seq_Bcells_Human1.18870443
101PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.18807865
102* RUNX1_22412390_ChIP-Seq_EML_Mouse1.18021916
103CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.18005463
104ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.17999444
105MYCN_18555785_ChIP-Seq_MESCs_Mouse1.16885758
106TP63_17297297_ChIP-ChIP_HaCaT_Human1.16728270
107YY1_22570637_ChIP-Seq_MALME-3M_Human1.16392518
108EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.15894769
109NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.15415925
110TP53_22127205_ChIP-Seq_IMR90_Human1.15399489
111* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.15254480
112CTCF_21964334_Chip-Seq_Bcells_Human1.14623070
113* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.13825043
114TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.13570784
115DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.13198867
116CTCF_20526341_ChIP-Seq_ESCs_Human1.12347818
117POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.12207241
118STAT4_19710469_ChIP-ChIP_TH1__Mouse1.11978972
119MYB_26560356_Chip-Seq_TH2_Human1.11651762
120STAT3_1855785_ChIP-Seq_MESCs_Mouse1.11300122
121KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.10861607
122SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.10822192
123KDM2B_26808549_Chip-Seq_JURKAT_Human1.10737762
124RARB_24833708_ChIP-Seq_LIVER_Mouse1.10519758
125MAF_26560356_Chip-Seq_TH2_Human1.10173996
126ELK3_25401928_ChIP-Seq_HUVEC_Human1.10075610
127EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.10030821
128KDM5A_27292631_Chip-Seq_BREAST_Human1.09942384
129ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.09076704
130PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09002226
131RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.08933850
132NANOG_18555785_ChIP-Seq_MESCs_Mouse1.08877706
133RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.08753705
134NOTCH1_21737748_ChIP-Seq_TLL_Human1.08633265
135CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.08450595
136DNAJC2_21179169_ChIP-ChIP_NT2_Human1.08058787
137HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.07936660
138LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.07888646
139CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.07447256
140CTCF_21964334_ChIP-Seq_BJAB-B_Human1.07349155
141* TCF7_22412390_ChIP-Seq_EML_Mouse1.07190223
142* GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.07145792
143* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.06988732
144PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.06265055
145MYB_26560356_Chip-Seq_TH1_Human1.06138522
146SPI1_23127762_ChIP-Seq_K562_Human1.05820862
147MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.05796543
148GATA2_22383799_ChIP-Seq_G1ME_Mouse1.05650611
149* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.05335441
150FOXP1_21924763_ChIP-Seq_HESCs_Human1.05066604
151AR_21909140_ChIP-Seq_LNCAP_Human1.03753953
152ELK1_19687146_ChIP-ChIP_HELA_Human1.03340747
153TFEB_21752829_ChIP-Seq_HELA_Human1.03229650
154E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.02346259
155CTCF_27219007_Chip-Seq_Bcells_Human1.02291216
156MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.01839334
157SRY_22984422_ChIP-ChIP_TESTIS_Rat1.01170038
158KLF4_18555785_ChIP-Seq_MESCs_Mouse1.00515330
159BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.96380162
160CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.95007987
161CTCF_18555785_ChIP-Seq_MESCs_Mouse0.92815202

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005058_abnormal_lysosome_morphology3.44726149
2MP0003693_abnormal_embryo_hatching3.41075997
3MP0002396_abnormal_hematopoietic_system3.31179726
4MP0006082_CNS_inflammation2.84001203
5MP0001835_abnormal_antigen_presentation2.61499423
6MP0000685_abnormal_immune_system2.48215188
7MP0010094_abnormal_chromosome_stability2.42051514
8MP0004957_abnormal_blastocyst_morpholog2.40535329
9MP0000490_abnormal_crypts_of2.39589222
10MP0008260_abnormal_autophagy2.38822178
11MP0006054_spinal_hemorrhage2.27681192
12MP0003111_abnormal_nucleus_morphology2.24556363
13MP0003077_abnormal_cell_cycle2.23879750
14MP0001545_abnormal_hematopoietic_system2.12747133
15MP0005397_hematopoietic_system_phenotyp2.12747133
16MP0009379_abnormal_foot_pigmentation2.12733476
17MP0009333_abnormal_splenocyte_physiolog2.11821557
18MP0003436_decreased_susceptibility_to2.10879341
19MP0002398_abnormal_bone_marrow2.00624600
20MP0004808_abnormal_hematopoietic_stem1.98060687
21MP0001800_abnormal_humoral_immune1.97313199
22MP0009785_altered_susceptibility_to1.94975563
23MP0003763_abnormal_thymus_physiology1.94415996
24MP0008007_abnormal_cellular_replicative1.89694966
25MP0000689_abnormal_spleen_morphology1.81877265
26MP0002722_abnormal_immune_system1.79769779
27MP0002166_altered_tumor_susceptibility1.77908130
28MP0002653_abnormal_ependyma_morphology1.77728437
29MP0002452_abnormal_antigen_presenting1.76807649
30MP0005025_abnormal_response_to1.76317134
31MP0005451_abnormal_body_composition1.74260185
32MP0001853_heart_inflammation1.72413118
33MP0002420_abnormal_adaptive_immunity1.71538041
34MP0001819_abnormal_immune_cell1.68448509
35MP0000716_abnormal_immune_system1.67916666
36MP0002429_abnormal_blood_cell1.66578409
37MP0003279_aneurysm1.62057417
38MP0009764_decreased_sensitivity_to1.61401774
39MP0002723_abnormal_immune_serum1.60630693
40MP0005000_abnormal_immune_tolerance1.57682084
41MP0003186_abnormal_redox_activity1.57005635
42MP0003806_abnormal_nucleotide_metabolis1.56141112
43MP0009840_abnormal_foam_cell1.56127141
44MP0002019_abnormal_tumor_incidence1.55688109
45MP0004858_abnormal_nervous_system1.54489321
46MP0005075_abnormal_melanosome_morpholog1.54209441
47MP0005671_abnormal_response_to1.52307455
48MP0000703_abnormal_thymus_morphology1.51523012
49MP0005464_abnormal_platelet_physiology1.50500272
50MP0005174_abnormal_tail_pigmentation1.49925652
51MP0001873_stomach_inflammation1.48670840
52MP0008058_abnormal_DNA_repair1.48563573
53MP0000465_gastrointestinal_hemorrhage1.46622513
54MP0010155_abnormal_intestine_physiology1.46560820
55MP0009278_abnormal_bone_marrow1.46333638
56MP0010352_gastrointestinal_tract_polyps1.42536066
57MP0002405_respiratory_system_inflammati1.41850987
58MP0002419_abnormal_innate_immunity1.41610966
59MP0001790_abnormal_immune_system1.41577762
60MP0005387_immune_system_phenotype1.41577762
61MP0000858_altered_metastatic_potential1.38497787
62MP0003075_altered_response_to1.38077075
63MP0003303_peritoneal_inflammation1.35841363
64MP0002132_abnormal_respiratory_system1.35566535
65MP0001542_abnormal_bone_strength1.34537629
66MP0002148_abnormal_hypersensitivity_rea1.31847783
67MP0002163_abnormal_gland_morphology1.30922714
68MP0006036_abnormal_mitochondrial_physio1.27674400
69MP0002006_tumorigenesis1.27220660
70MP0008057_abnormal_DNA_replication1.24877135
71MP0003656_abnormal_erythrocyte_physiolo1.22890786
72MP0004510_myositis1.22711538
73MP0001845_abnormal_inflammatory_respons1.22221226
74MP0000313_abnormal_cell_death1.19993414
75MP0005390_skeleton_phenotype1.19529240
76MP0000350_abnormal_cell_proliferation1.17693979
77MP0000604_amyloidosis1.13000654
78MP0003724_increased_susceptibility_to1.11583690
79MP0008932_abnormal_embryonic_tissue1.08970395
80MP0008469_abnormal_protein_level1.08502862
81MP0000681_abnormal_thyroid_gland1.06399402
82MP0003866_abnormal_defecation1.05554715
83MP0003191_abnormal_cellular_cholesterol1.04639807
84MP0002095_abnormal_skin_pigmentation1.04592098
85MP0010307_abnormal_tumor_latency1.04503950
86MP0001730_embryonic_growth_arrest1.02348733
87MP0003300_gastrointestinal_ulcer1.00854502
88MP0000750_abnormal_muscle_regeneration1.00152222
89MP0002998_abnormal_bone_remodeling0.99994719
90MP0005381_digestive/alimentary_phenotyp0.98815739
91MP0005220_abnormal_exocrine_pancreas0.97286656
92MP0003786_premature_aging0.95310215
93MP0001849_ear_inflammation0.92187591
94MP0000598_abnormal_liver_morphology0.89675747
95MP0003183_abnormal_peptide_metabolism0.89540480
96MP0000678_abnormal_parathyroid_gland0.87799237
97MP0000358_abnormal_cell_content/0.87738149
98MP0005165_increased_susceptibility_to0.87271978
99MP0002080_prenatal_lethality0.87139886
100MP0000477_abnormal_intestine_morphology0.85876213
101MP0005310_abnormal_salivary_gland0.84815105
102MP0004947_skin_inflammation0.84468290
103MP0003123_paternal_imprinting0.82970758
104MP0005083_abnormal_biliary_tract0.82406683
105MP0001533_abnormal_skeleton_physiology0.82004560
106MP0001663_abnormal_digestive_system0.81678015
107MP0001958_emphysema0.80451177
108MP0001348_abnormal_lacrimal_gland0.79761993
109MP0005166_decreased_susceptibility_to0.79082472
110MP0003828_pulmonary_edema0.76459766
111MP0005023_abnormal_wound_healing0.75745548
112MP0009643_abnormal_urine_homeostasis0.75468346
113MP0005319_abnormal_enzyme/_coenzyme0.75223673
114MP0003795_abnormal_bone_structure0.74727144
115MP0009765_abnormal_xenobiotic_induced0.73689078
116MP0000015_abnormal_ear_pigmentation0.73434664
117MP0008004_abnormal_stomach_pH0.73024622
118MP0000609_abnormal_liver_physiology0.72841704
119MP0005584_abnormal_enzyme/coenzyme_acti0.71888264
120MP0001764_abnormal_homeostasis0.70780198
121MP0003705_abnormal_hypodermis_morpholog0.70554408
122MP0003329_amyloid_beta_deposits0.70392796
123MP0003567_abnormal_fetal_cardiomyocyte0.70284674
124MP0005360_urolithiasis0.69393386
125MP0002254_reproductive_system_inflammat0.68858613
126MP0001697_abnormal_embryo_size0.68533564
127MP0000343_altered_response_to0.68306917
128MP0004185_abnormal_adipocyte_glucose0.67710259
129MP0009763_increased_sensitivity_to0.67623579
130MP0002970_abnormal_white_adipose0.67534346
131MP0005257_abnormal_intraocular_pressure0.67259213
132MP0005670_abnormal_white_adipose0.66372726
133MP0002138_abnormal_hepatobiliary_system0.66111606
134MP0002933_joint_inflammation0.65922635
135MP0003448_altered_tumor_morphology0.65475653
136MP0009931_abnormal_skin_appearance0.63752084
137MP0001915_intracranial_hemorrhage0.62635702
138MP0005365_abnormal_bile_salt0.62000912
139MP0006035_abnormal_mitochondrial_morpho0.60899210
140MP0003172_abnormal_lysosome_physiology0.60149210
141MP0002089_abnormal_postnatal_growth/wei0.59019007
142MP0002277_abnormal_respiratory_mucosa0.56250237

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)6.23315149
2Abnormal number of erythroid precursors (HP:0012131)6.10390375
3Reticulocytopenia (HP:0001896)5.40027404
4Thrombocytosis (HP:0001894)4.48288222
5Abnormality of glycolipid metabolism (HP:0010969)3.92256808
6Abnormality of liposaccharide metabolism (HP:0010968)3.92256808
7Abnormality of glycosphingolipid metabolism (HP:0004343)3.92256808
8Abnormality of macrophages (HP:0004311)3.89902254
9Pallor (HP:0000980)3.81744444
10Achilles tendon contracture (HP:0001771)3.73058087
11Aplastic anemia (HP:0001915)3.70749774
12Macrocytic anemia (HP:0001972)3.62679275
13Elevated erythrocyte sedimentation rate (HP:0003565)3.50312713
14IgM deficiency (HP:0002850)3.34383451
15Obstructive lung disease (HP:0006536)3.33583733
16Chronic obstructive pulmonary disease (HP:0006510)3.33583733
17Abnormality of the Achilles tendon (HP:0005109)3.25448194
18Vertebral compression fractures (HP:0002953)3.19538605
19Cellulitis (HP:0100658)3.17933308
20Dysostosis multiplex (HP:0000943)3.12244396
21Petechiae (HP:0000967)3.04266791
22Chronic otitis media (HP:0000389)3.01914022
23Oral leukoplakia (HP:0002745)2.82250406
24Reduced antithrombin III activity (HP:0001976)2.81582355
25Purpura (HP:0000979)2.81354527
26Agammaglobulinemia (HP:0004432)2.79651974
27Recurrent bronchitis (HP:0002837)2.77042867
28Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.76751452
29Decreased activity of mitochondrial respiratory chain (HP:0008972)2.76751452
30B lymphocytopenia (HP:0010976)2.75560881
31Abnormality of B cell number (HP:0010975)2.75560881
32Amyloidosis (HP:0011034)2.71065806
33Recurrent viral infections (HP:0004429)2.70828664
34Increased cerebral lipofuscin (HP:0011813)2.66803461
35Vacuolated lymphocytes (HP:0001922)2.65374616
36Abnormality of polysaccharide metabolism (HP:0011012)2.64921056
37Abnormality of glycosaminoglycan metabolism (HP:0004371)2.64921056
38Abnormality of mucopolysaccharide metabolism (HP:0011020)2.64921056
39Hepatosplenomegaly (HP:0001433)2.63811215
40Papilloma (HP:0012740)2.63031972
41Verrucae (HP:0200043)2.63031972
42Systemic lupus erythematosus (HP:0002725)2.62788938
43Orchitis (HP:0100796)2.62300175
44Increased IgE level (HP:0003212)2.60283806
45Multiple enchondromatosis (HP:0005701)2.59466401
46Meningitis (HP:0001287)2.58282229
47Type I transferrin isoform profile (HP:0003642)2.55899871
48Abnormality of T cell physiology (HP:0011840)2.54598107
49Hypertensive crisis (HP:0100735)2.52756382
50Hepatic necrosis (HP:0002605)2.51838065
51Microretrognathia (HP:0000308)2.51574840
52Panhypogammaglobulinemia (HP:0003139)2.49030386
53Stomatitis (HP:0010280)2.43068583
54Urinary glycosaminoglycan excretion (HP:0003541)2.40959605
55Mucopolysacchariduria (HP:0008155)2.40959605
56Prolonged neonatal jaundice (HP:0006579)2.40884792
57Abnormality of reticulocytes (HP:0004312)2.40245190
58Gastrointestinal inflammation (HP:0004386)2.39642580
59Recurrent gram-negative bacterial infections (HP:0005420)2.37207878
60Hepatocellular necrosis (HP:0001404)2.34475434
61Increased neuronal autofluorescent lipopigment (HP:0002074)2.34371999
62Aplasia/Hypoplasia of the sacrum (HP:0008517)2.34176053
63Abnormality of the heme biosynthetic pathway (HP:0010472)2.33210257
64Loss of speech (HP:0002371)2.33009904
6511 pairs of ribs (HP:0000878)2.32570214
66Urticaria (HP:0001025)2.31798165
67Exertional dyspnea (HP:0002875)2.26922223
68Prolonged bleeding time (HP:0003010)2.22283774
69Joint stiffness (HP:0001387)2.22045327
70Inflammation of the large intestine (HP:0002037)2.21957143
71Upper motor neuron abnormality (HP:0002127)2.21766404
72Abnormal protein glycosylation (HP:0012346)2.20888323
73Abnormal glycosylation (HP:0012345)2.20888323
74Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.20888323
75Abnormal protein N-linked glycosylation (HP:0012347)2.20888323
76Recurrent abscess formation (HP:0002722)2.20793405
77Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.20744978
78Hypoplasia of the thymus (HP:0000778)2.20618725
79Increased muscle lipid content (HP:0009058)2.19899695
80Gastrointestinal infarctions (HP:0005244)2.19861352
81Cervical subluxation (HP:0003308)2.19445082
82Polygenic inheritance (HP:0010982)2.18685534
83Nasal polyposis (HP:0100582)2.18533547
84Short femoral neck (HP:0100864)2.17068996
85Colon cancer (HP:0003003)2.16265423
86Episodic fever (HP:0001954)2.15563978
87Impaired platelet aggregation (HP:0003540)2.15353021
88Abnormal platelet function (HP:0011869)2.15353021
89Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)2.12897613
90Myositis (HP:0100614)2.12676594
91Abnormality of T cells (HP:0002843)2.12579296
92Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.12414873
93Recurrent fungal infections (HP:0002841)2.11907931
94Increased intramyocellular lipid droplets (HP:0012240)2.10381303
95Abnormality of the nasal mucosa (HP:0000433)2.09846458
96Recurrent cutaneous fungal infections (HP:0011370)2.09106341
97Chronic mucocutaneous candidiasis (HP:0002728)2.09106341
98Increased IgM level (HP:0003496)2.08436531
99Recurrent bacterial skin infections (HP:0005406)2.07400664
100Thoracic kyphosis (HP:0002942)2.06411408
101Pancytopenia (HP:0001876)2.02669757
102Abnormal delayed hypersensitivity skin test (HP:0002963)2.01394012
103Lymphoma (HP:0002665)2.00566798
104Increased serum ferritin (HP:0003281)1.98976695
105Skin rash (HP:0000988)1.98401053
106Poikiloderma (HP:0001029)1.97500052
107Abnormality of cells of the lymphoid lineage (HP:0012140)1.95744276
108Progressive neurologic deterioration (HP:0002344)1.95610656
109Colitis (HP:0002583)1.95504401
110Opisthotonus (HP:0002179)1.95274334
111Encephalitis (HP:0002383)1.93746146
112Lipid accumulation in hepatocytes (HP:0006561)1.93652798
113Retrobulbar optic neuritis (HP:0100654)1.93000443
114Optic neuritis (HP:0100653)1.93000443
115Increased serum lactate (HP:0002151)1.92783794
116Spondylolisthesis (HP:0003302)1.92214909
117Hypergammaglobulinemia (HP:0010702)1.92110930
118Microcytic anemia (HP:0001935)1.92092709
119Peritonitis (HP:0002586)1.90381023
120Ragged-red muscle fibers (HP:0003200)1.89397334
121Poor head control (HP:0002421)1.89259403
122Selective tooth agenesis (HP:0001592)1.89108426
123Neutropenia (HP:0001875)1.89048542
124Epistaxis (HP:0000421)1.88283646
125Absent rod-and cone-mediated responses on ERG (HP:0007688)1.87809436
126Progressive muscle weakness (HP:0003323)1.87788051
127Gingivitis (HP:0000230)1.86865965
128Lymphopenia (HP:0001888)1.86557090
129Increased hepatocellular lipid droplets (HP:0006565)1.84997506
130Mediastinal lymphadenopathy (HP:0100721)1.83557238
131Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.83491743
132Protrusio acetabuli (HP:0003179)1.83269494
133Axonal loss (HP:0003447)1.81510772
134Vasculitis (HP:0002633)1.80065893
135Osteomyelitis (HP:0002754)1.79933830
136Hypertriglyceridemia (HP:0002155)1.79585729
137Aplasia/Hypoplasia of the thymus (HP:0010515)1.79074571
138Granulocytopenia (HP:0001913)1.78616851
139Generalized aminoaciduria (HP:0002909)1.78357116
140Abnormality of pyrimidine metabolism (HP:0004353)1.76984779
141Fatigue (HP:0012378)1.76924147
142Pustule (HP:0200039)1.76534233
143Chronic sinusitis (HP:0011109)1.75908151
144Mitochondrial inheritance (HP:0001427)1.75797689
145Sepsis (HP:0100806)1.74543185
146Abnormality of iron homeostasis (HP:0011031)1.74065917
147Difficulty running (HP:0009046)1.73002083
148Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.72544236
149Emphysema (HP:0002097)1.72376011
150Recurrent lower respiratory tract infections (HP:0002783)1.71218905
151Increased CSF lactate (HP:0002490)1.71108183
152Eczematoid dermatitis (HP:0000976)1.70979192
153Hemorrhage of the eye (HP:0011885)1.70502096
154Gastrointestinal stroma tumor (HP:0100723)1.67479035
155Absent thumb (HP:0009777)1.66922556
156Trismus (HP:0000211)1.66857314
157Dicarboxylic aciduria (HP:0003215)1.66023363
158Abnormality of dicarboxylic acid metabolism (HP:0010995)1.66023363
159Abnormal hemoglobin (HP:0011902)1.65930728
160Recurrent skin infections (HP:0001581)1.65631052
161Myelodysplasia (HP:0002863)1.65027544
162Combined immunodeficiency (HP:0005387)1.64979906
163Respiratory difficulties (HP:0002880)1.64191760
164Severe combined immunodeficiency (HP:0004430)1.64139025
165Skin ulcer (HP:0200042)1.63788574
166Degeneration of anterior horn cells (HP:0002398)1.62382337
167Abnormality of the anterior horn cell (HP:0006802)1.62382337

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K103.60049313
2NME23.31596172
3ERN12.87632897
4MAP4K12.82159641
5EEF2K2.81287846
6LIMK12.42087356
7PKN22.37792047
8WEE12.29729671
9BUB12.25842006
10PIM22.23189181
11TRIB32.23162216
12STK162.17207226
13BCKDK2.13250550
14TLK12.05263128
15IRAK31.98663528
16SCYL21.98234124
17EIF2AK31.92889529
18LRRK21.90659189
19FLT31.85084473
20BLK1.84112183
21NEK21.81845697
22ARAF1.78535564
23KDR1.77677940
24TESK21.76945973
25DYRK31.75932180
26BTK1.70751169
27RPS6KB21.69854622
28CDC71.66080637
29SMG11.63363701
30VRK11.61847367
31GRK61.57873346
32PRPF4B1.55327067
33RPS6KA41.51571288
34TAOK21.50428524
35ACVR1B1.45644311
36MAP3K111.41623271
37TBK11.37967719
38RIPK41.36509840
39VRK21.33618907
40TGFBR11.32484786
41MAPKAPK31.31365889
42KIT1.27870069
43EPHB11.25980684
44BRSK21.25584870
45MAP2K31.24887695
46PASK1.23156810
47ABL21.23053593
48TYK21.21838882
49TAOK11.21411618
50CDK41.21348535
51PRKD21.19789325
52PIM11.17955375
53EIF2AK11.17388857
54TEC1.17201155
55CSF1R1.17086971
56CDK71.16799748
57ZAP701.16107631
58TNK21.15521740
59CSK1.13746300
60BRAF1.03400298
61SYK1.02405057
62ILK1.00321961
63MAP3K80.99394519
64STK40.98522444
65EPHB20.97764573
66STK100.96397862
67TESK10.94817000
68MAP3K130.92655375
69AURKB0.91292336
70EPHA20.91038110
71ICK0.90508905
72ATR0.89544061
73IRAK40.89542241
74MOS0.88465354
75MAP3K140.87266257
76JAK30.86227730
77CDC42BPA0.86118089
78CDK190.85558215
79CLK10.84655643
80PAK40.82779357
81LMTK20.81782206
82MARK30.78281797
83MAP3K10.76662059
84BRSK10.74635857
85RPS6KA20.74115117
86DYRK1B0.73865324
87LYN0.73663956
88MAPK110.72749128
89MARK20.72513191
90PDPK10.71128909
91IKBKB0.68125794
92IKBKE0.67680576
93MAPK40.64572664
94PLK10.63326752
95SRPK10.62671639
96AURKA0.62318457
97RIPK10.61422823
98IRAK20.61264999
99CCNB10.59931730
100MATK0.59631595
101PDK10.57827854
102TGFBR20.53518716
103NLK0.50945239
104SIK10.50380650
105MAP2K20.49328623
106CDK80.48124663
107FGR0.46793230
108TXK0.46253251
109LCK0.45726089
110GRK70.45337285
111RPS6KA60.44605671
112MAP3K30.43876674
113RPS6KA50.43658823
114PAK10.43330524
115CHEK20.42824551
116ZAK0.42561448
117PTK60.41269496
118DAPK30.40648877
119SIK20.39321243
120CSNK2A20.39208554
121AKT20.37980181
122MAPKAPK20.37917801
123RPS6KL10.37158762
124RPS6KC10.37158762
125CSNK2A10.36862982
126TTK0.36724854
127HIPK20.36095568
128MAP3K60.36011180
129CDK60.35786227
130PRKCD0.34215625
131HCK0.34202068
132FES0.34119866
133PRKD10.33850425
134DYRK20.33206250
135MKNK10.31557568
136TAOK30.31520383
137NEK10.31188670
138FYN0.31056735
139RAF10.30965543
140PIK3CG0.30822834
141SIK30.30764352
142PRKG20.30724143
143DDR20.30293508

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.22544490
2DNA replication_Homo sapiens_hsa030304.81431218
3Mismatch repair_Homo sapiens_hsa034303.43830411
4Base excision repair_Homo sapiens_hsa034103.02191035
5Proteasome_Homo sapiens_hsa030502.46980527
6Homologous recombination_Homo sapiens_hsa034402.37085365
7Spliceosome_Homo sapiens_hsa030402.34126382
8Pyrimidine metabolism_Homo sapiens_hsa002402.19519622
9Allograft rejection_Homo sapiens_hsa053302.18592597
10One carbon pool by folate_Homo sapiens_hsa006702.12015524
11Nucleotide excision repair_Homo sapiens_hsa034202.03810055
12Graft-versus-host disease_Homo sapiens_hsa053322.00603879
13Sulfur relay system_Homo sapiens_hsa041222.00492800
14Autoimmune thyroid disease_Homo sapiens_hsa053202.00018123
15Staphylococcus aureus infection_Homo sapiens_hsa051501.96375661
16Asthma_Homo sapiens_hsa053101.93536572
17Lysosome_Homo sapiens_hsa041421.79061611
18Primary immunodeficiency_Homo sapiens_hsa053401.74593939
19RNA polymerase_Homo sapiens_hsa030201.70885728
20Systemic lupus erythematosus_Homo sapiens_hsa053221.69203718
21Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.61252573
22Non-homologous end-joining_Homo sapiens_hsa034501.58871624
23Malaria_Homo sapiens_hsa051441.53931788
24Cell cycle_Homo sapiens_hsa041101.52419347
25Tuberculosis_Homo sapiens_hsa051521.51095592
26Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.50706293
27Folate biosynthesis_Homo sapiens_hsa007901.49293148
28Protein export_Homo sapiens_hsa030601.46046961
29RNA transport_Homo sapiens_hsa030131.45501940
30Viral myocarditis_Homo sapiens_hsa054161.41905001
31Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.41422259
32Phagosome_Homo sapiens_hsa041451.33656937
33Notch signaling pathway_Homo sapiens_hsa043301.32590821
34Rheumatoid arthritis_Homo sapiens_hsa053231.28600459
35N-Glycan biosynthesis_Homo sapiens_hsa005101.27078644
36Drug metabolism - other enzymes_Homo sapiens_hsa009831.26600440
37Salmonella infection_Homo sapiens_hsa051321.26578133
38Type I diabetes mellitus_Homo sapiens_hsa049401.23950849
39Fructose and mannose metabolism_Homo sapiens_hsa000511.23407840
40p53 signaling pathway_Homo sapiens_hsa041151.18271110
41Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.18041499
42Cyanoamino acid metabolism_Homo sapiens_hsa004601.13619112
43Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.12931113
44Antigen processing and presentation_Homo sapiens_hsa046121.11562190
45B cell receptor signaling pathway_Homo sapiens_hsa046621.11531004
46Fanconi anemia pathway_Homo sapiens_hsa034601.10212181
47NOD-like receptor signaling pathway_Homo sapiens_hsa046211.07565612
48SNARE interactions in vesicular transport_Homo sapiens_hsa041301.03728222
49Herpes simplex infection_Homo sapiens_hsa051681.02702745
50Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.99652568
51RNA degradation_Homo sapiens_hsa030180.97718777
52* Pentose phosphate pathway_Homo sapiens_hsa000300.97489797
53Fatty acid elongation_Homo sapiens_hsa000620.94510034
54Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.94462818
55Purine metabolism_Homo sapiens_hsa002300.92010640
56Biosynthesis of amino acids_Homo sapiens_hsa012300.90977836
57Parkinsons disease_Homo sapiens_hsa050120.90763976
58Selenocompound metabolism_Homo sapiens_hsa004500.90454843
59Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.89858573
60Viral carcinogenesis_Homo sapiens_hsa052030.85993482
61Legionellosis_Homo sapiens_hsa051340.85462795
62TNF signaling pathway_Homo sapiens_hsa046680.84605169
63Leishmaniasis_Homo sapiens_hsa051400.83757181
64Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.82871237
65Epstein-Barr virus infection_Homo sapiens_hsa051690.81610520
66Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.81120988
672-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.80538189
68Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.80306707
69Apoptosis_Homo sapiens_hsa042100.79859553
70Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.78943062
71Other glycan degradation_Homo sapiens_hsa005110.78525312
72Hepatitis C_Homo sapiens_hsa051600.76759967
73Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.75784767
74NF-kappa B signaling pathway_Homo sapiens_hsa040640.74637659
75Acute myeloid leukemia_Homo sapiens_hsa052210.74526274
76Glutathione metabolism_Homo sapiens_hsa004800.73598805
77Measles_Homo sapiens_hsa051620.73391281
78Vibrio cholerae infection_Homo sapiens_hsa051100.73294313
79Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.73109433
80* Carbon metabolism_Homo sapiens_hsa012000.72662864
81Chemokine signaling pathway_Homo sapiens_hsa040620.72540296
82Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.71096744
83Cysteine and methionine metabolism_Homo sapiens_hsa002700.70602275
84Galactose metabolism_Homo sapiens_hsa000520.70182521
85Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.69996520
86Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.69272261
87RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.68163079
88Endocytosis_Homo sapiens_hsa041440.67752983
89Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.67092164
90Shigellosis_Homo sapiens_hsa051310.66884494
91Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.66669532
92Intestinal immune network for IgA production_Homo sapiens_hsa046720.66548059
93Hematopoietic cell lineage_Homo sapiens_hsa046400.66272908
94Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.65825515
95Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.64403871
96Transcriptional misregulation in cancer_Homo sapiens_hsa052020.63040079
97Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.62881765
98Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.62224248
99HTLV-I infection_Homo sapiens_hsa051660.61484429
100VEGF signaling pathway_Homo sapiens_hsa043700.60522393
101Oxidative phosphorylation_Homo sapiens_hsa001900.60479394
102Pentose and glucuronate interconversions_Homo sapiens_hsa000400.60271142
103Chronic myeloid leukemia_Homo sapiens_hsa052200.57920234
104Sulfur metabolism_Homo sapiens_hsa009200.56911623
105Huntingtons disease_Homo sapiens_hsa050160.56389001
106Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.56364684
107Hepatitis B_Homo sapiens_hsa051610.55127300
108Small cell lung cancer_Homo sapiens_hsa052220.55067224
109Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.54595632
110Thyroid cancer_Homo sapiens_hsa052160.52928232
111Glycosaminoglycan degradation_Homo sapiens_hsa005310.52050254
112Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.51781676
113Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.51756455
114Leukocyte transendothelial migration_Homo sapiens_hsa046700.51532867
115Collecting duct acid secretion_Homo sapiens_hsa049660.51254756
116Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.50986990
117Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.49588286
118Alcoholism_Homo sapiens_hsa050340.49141892
119Fatty acid degradation_Homo sapiens_hsa000710.47490164
120Bladder cancer_Homo sapiens_hsa052190.47469112
121Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.45596629
122Pancreatic cancer_Homo sapiens_hsa052120.45396377
123African trypanosomiasis_Homo sapiens_hsa051430.44473190
124Arachidonic acid metabolism_Homo sapiens_hsa005900.44469790
125Renin-angiotensin system_Homo sapiens_hsa046140.44342690
126Influenza A_Homo sapiens_hsa051640.44162962
127Basal transcription factors_Homo sapiens_hsa030220.43378127
128mRNA surveillance pathway_Homo sapiens_hsa030150.42707168
129Adipocytokine signaling pathway_Homo sapiens_hsa049200.40901524
130Osteoclast differentiation_Homo sapiens_hsa043800.39081363
131Peroxisome_Homo sapiens_hsa041460.38664903
132T cell receptor signaling pathway_Homo sapiens_hsa046600.38523945
133Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.37050304
134Jak-STAT signaling pathway_Homo sapiens_hsa046300.36975750
135Caffeine metabolism_Homo sapiens_hsa002320.36935043
136Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.36931333
137Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.36335296
138* Metabolic pathways_Homo sapiens_hsa011000.34286341
139Central carbon metabolism in cancer_Homo sapiens_hsa052300.33135720
140Neurotrophin signaling pathway_Homo sapiens_hsa047220.33028364
141Glycerophospholipid metabolism_Homo sapiens_hsa005640.31976538
142Toxoplasmosis_Homo sapiens_hsa051450.31738666
143Non-small cell lung cancer_Homo sapiens_hsa052230.31719323
144Toll-like receptor signaling pathway_Homo sapiens_hsa046200.30460126
145Pertussis_Homo sapiens_hsa051330.29000184
146Alzheimers disease_Homo sapiens_hsa050100.28855444
147Pyruvate metabolism_Homo sapiens_hsa006200.25045790

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