PGBD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. This gene product is specifically expressed in the brain, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1doxorubicin metabolic process (GO:0044598)4.55466996
2daunorubicin metabolic process (GO:0044597)4.55466996
3polyketide metabolic process (GO:0030638)4.55466996
4regulation of cilium movement (GO:0003352)4.45550070
5protein localization to cilium (GO:0061512)4.45319753
6intraciliary transport (GO:0042073)4.41015209
7deoxyribose phosphate biosynthetic process (GO:0046385)4.40044808
82-deoxyribonucleotide biosynthetic process (GO:0009265)4.40044808
9pyrimidine nucleobase catabolic process (GO:0006208)4.35645356
10regulation of cardioblast proliferation (GO:0003264)4.16729174
11regulation of secondary heart field cardioblast proliferation (GO:0003266)4.16729174
12deoxyribonucleotide biosynthetic process (GO:0009263)4.05420982
13retinal rod cell development (GO:0046548)4.01880731
14cilium or flagellum-dependent cell motility (GO:0001539)4.01767934
15behavioral response to nicotine (GO:0035095)3.79755460
16nonmotile primary cilium assembly (GO:0035058)3.77088129
17DNA damage response, detection of DNA damage (GO:0042769)3.71629128
18chromatin remodeling at centromere (GO:0031055)3.69898052
19limb bud formation (GO:0060174)3.69146481
20motile cilium assembly (GO:0044458)3.51510234
21proteasome assembly (GO:0043248)3.40906630
22neural tube formation (GO:0001841)3.36362967
23nucleobase catabolic process (GO:0046113)3.34984563
24deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.34445239
25guanosine-containing compound biosynthetic process (GO:1901070)3.26723987
26replication fork processing (GO:0031297)3.23058574
27presynaptic membrane assembly (GO:0097105)3.19555727
28striatum development (GO:0021756)3.19444290
29microtubule depolymerization (GO:0007019)3.09938483
30cardiac right ventricle morphogenesis (GO:0003215)3.09922254
31regulation of double-strand break repair via homologous recombination (GO:0010569)3.09269403
32protein deneddylation (GO:0000338)3.08611265
33regulation of meiosis I (GO:0060631)3.08029780
34kinetochore organization (GO:0051383)3.07825322
35behavioral response to ethanol (GO:0048149)3.07539478
36sister chromatid segregation (GO:0000819)3.06199363
37meiotic chromosome segregation (GO:0045132)3.03913145
38GTP biosynthetic process (GO:0006183)3.03294095
39DNA replication checkpoint (GO:0000076)3.02933030
40epithelial cilium movement (GO:0003351)3.02136747
41sperm-egg recognition (GO:0035036)3.00531559
42glial cell proliferation (GO:0014009)3.00499055
43somatic hypermutation of immunoglobulin genes (GO:0016446)2.96029648
44somatic diversification of immune receptors via somatic mutation (GO:0002566)2.96029648
45G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.95890827
46protein K6-linked ubiquitination (GO:0085020)2.94591285
47atrial septum morphogenesis (GO:0060413)2.93784026
48presynaptic membrane organization (GO:0097090)2.92637049
49mesenchyme morphogenesis (GO:0072132)2.91985346
50UTP biosynthetic process (GO:0006228)2.89624460
51centriole replication (GO:0007099)2.88449971
52postsynaptic membrane organization (GO:0001941)2.87942021
53resolution of meiotic recombination intermediates (GO:0000712)2.86241632
54adenosine metabolic process (GO:0046085)2.86046687
55olfactory bulb development (GO:0021772)2.85481328
56viral mRNA export from host cell nucleus (GO:0046784)2.84225001
57pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.83780551
58nephron epithelium morphogenesis (GO:0072088)2.82206455
59nephron tubule morphogenesis (GO:0072078)2.82206455
60epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.81047326
61spermatid nucleus differentiation (GO:0007289)2.80187625
62outflow tract septum morphogenesis (GO:0003148)2.79693467
63aminoglycoside antibiotic metabolic process (GO:0030647)2.79624033
64regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.79552937
65histone exchange (GO:0043486)2.78493783
66negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)2.78151549
67protein localization to synapse (GO:0035418)2.77961363
68lactate metabolic process (GO:0006089)2.76869052
69endocardial cushion morphogenesis (GO:0003203)2.76615773
70heterochromatin organization (GO:0070828)2.76258024
71DNA catabolic process, exonucleolytic (GO:0000738)2.75632964
72positive regulation of mitochondrial fission (GO:0090141)2.75565001
73regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.75388117
74acrosome assembly (GO:0001675)2.74488332
75multicellular organism reproduction (GO:0032504)2.73727411
76sympathetic nervous system development (GO:0048485)2.73676482
77regulation of synapse maturation (GO:0090128)2.73385930
78eye photoreceptor cell development (GO:0042462)2.73232811
79cell wall macromolecule catabolic process (GO:0016998)2.73188833
80cell wall macromolecule metabolic process (GO:0044036)2.73188833
81maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.72607248
82regulation of centriole replication (GO:0046599)2.72286655
83nucleotide-excision repair, DNA gap filling (GO:0006297)2.69837515
84positive regulation of synapse maturation (GO:0090129)2.69676250
85metaphase plate congression (GO:0051310)2.69002391
86neurotransmitter-gated ion channel clustering (GO:0072578)2.68984641
87innervation (GO:0060384)2.68883790
88histone H2A acetylation (GO:0043968)2.68711020
89axonemal dynein complex assembly (GO:0070286)2.67640612
90cilium movement (GO:0003341)2.67421398
91telomere maintenance via semi-conservative replication (GO:0032201)2.66639531
92mitotic metaphase plate congression (GO:0007080)2.64222870
93DNA double-strand break processing (GO:0000729)2.63719743
94regulation of centrosome cycle (GO:0046605)2.63644928
95photoreceptor cell development (GO:0042461)2.63418648
96cullin deneddylation (GO:0010388)2.62750199
97gamma-aminobutyric acid signaling pathway (GO:0007214)2.62574011
98negative regulation of transcription regulatory region DNA binding (GO:2000678)2.62014598
99cilium assembly (GO:0042384)2.61499888
100spindle checkpoint (GO:0031577)2.59527260
101mitochondrial respiratory chain complex I assembly (GO:0032981)2.57739860
102NADH dehydrogenase complex assembly (GO:0010257)2.57739860
103mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.57739860
104nucleobase biosynthetic process (GO:0046112)2.57169131
105kinetochore assembly (GO:0051382)2.56567866
106mitochondrial respiratory chain complex assembly (GO:0033108)2.56465047
107protein complex biogenesis (GO:0070271)2.55467262
108specification of organ identity (GO:0010092)2.54739852
109regulation of centrosome duplication (GO:0010824)2.54673797
110pyrimidine dimer repair (GO:0006290)2.54251724
111neuron cell-cell adhesion (GO:0007158)2.54237937
112regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.53514526
113regulation of mitotic spindle checkpoint (GO:1903504)2.53514526
114binding of sperm to zona pellucida (GO:0007339)2.53341126
115mitotic spindle checkpoint (GO:0071174)2.53282600
116pharyngeal system development (GO:0060037)2.52614291
117establishment of protein localization to mitochondrial membrane (GO:0090151)2.52191697
118cilium organization (GO:0044782)2.52060739
119pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.51837209
120pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.51759780
121axonal fasciculation (GO:0007413)2.51215319
122mismatch repair (GO:0006298)2.50377365
123negative regulation of mRNA processing (GO:0050686)2.50347930
124ubiquinone metabolic process (GO:0006743)2.49259544
125postreplication repair (GO:0006301)2.48455934
126recombinational repair (GO:0000725)2.48015582
127cell-cell recognition (GO:0009988)2.47128260
128regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.47093064
129protein K11-linked ubiquitination (GO:0070979)2.46838583
130exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.46465419
131protein-cofactor linkage (GO:0018065)2.46307916
132mitotic recombination (GO:0006312)2.46254841
133somite rostral/caudal axis specification (GO:0032525)2.46250437
134DNA replication-independent nucleosome organization (GO:0034724)2.45968719
135DNA replication-independent nucleosome assembly (GO:0006336)2.45968719
136nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.45693008
137protein polyglutamylation (GO:0018095)2.45426912
138establishment of integrated proviral latency (GO:0075713)2.45214013
139regulation of somitogenesis (GO:0014807)2.44679737
140double-strand break repair via homologous recombination (GO:0000724)2.44585472
141centriole assembly (GO:0098534)2.44390607
142sperm motility (GO:0030317)2.43728877
143microtubule anchoring (GO:0034453)2.43557801
144retinal ganglion cell axon guidance (GO:0031290)2.43302963
145regulation of non-canonical Wnt signaling pathway (GO:2000050)2.43218247
146negative regulation of DNA-dependent DNA replication (GO:2000104)2.43157025
147sperm capacitation (GO:0048240)2.42374890
148mitotic sister chromatid segregation (GO:0000070)2.42317235
149fusion of sperm to egg plasma membrane (GO:0007342)2.42142684
150limb development (GO:0060173)2.41602349
151appendage development (GO:0048736)2.41602349
152positive regulation of male gonad development (GO:2000020)2.41393883
153microtubule polymerization or depolymerization (GO:0031109)2.40845057
154regulation of mRNA splicing, via spliceosome (GO:0048024)2.40564607
155spermatid development (GO:0007286)2.40462143
156ubiquinone biosynthetic process (GO:0006744)2.40362885
157synaptic vesicle docking involved in exocytosis (GO:0016081)2.40225291
158purine nucleobase biosynthetic process (GO:0009113)2.40196227
159mitotic sister chromatid cohesion (GO:0007064)2.39138756
160UTP metabolic process (GO:0046051)2.38280100
161GMP metabolic process (GO:0046037)2.37760853
162DNA strand elongation involved in DNA replication (GO:0006271)2.37403123
163paraxial mesoderm development (GO:0048339)2.36694783
164inner ear receptor stereocilium organization (GO:0060122)2.35511783
165auditory receptor cell stereocilium organization (GO:0060088)2.35398633
166positive regulation of gastrulation (GO:2000543)2.35375243
167negative regulation of mitotic sister chromatid separation (GO:2000816)2.35295280
168negative regulation of sister chromatid segregation (GO:0033046)2.35295280
169negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.35295280
170negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.35295280
171negative regulation of mitotic sister chromatid segregation (GO:0033048)2.35295280
172negative regulation of DNA recombination (GO:0045910)2.35060492
173CENP-A containing nucleosome assembly (GO:0034080)2.34760545
174deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.34696626
175deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.34576951
176negative regulation of meiosis (GO:0045835)2.33280897
177response to pheromone (GO:0019236)2.33273156
178mitotic spindle assembly checkpoint (GO:0007094)2.33272319
179serotonin metabolic process (GO:0042428)2.32629551
180spinal cord development (GO:0021510)2.32221231
181positive regulation of dendritic spine morphogenesis (GO:0061003)2.31939581
182DNA unwinding involved in DNA replication (GO:0006268)2.31934950

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RBPJ_22232070_ChIP-Seq_NCS_Mouse3.80596685
2GBX2_23144817_ChIP-Seq_PC3_Human3.36316539
3GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.10476949
4E2F7_22180533_ChIP-Seq_HELA_Human3.09921553
5GABP_17652178_ChIP-ChIP_JURKAT_Human2.96521088
6GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.70276230
7EZH2_22144423_ChIP-Seq_EOC_Human2.65601087
8MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.51730436
9FUS_26573619_Chip-Seq_HEK293_Human2.47109836
10E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.39967605
11NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.38696714
12ELK1_19687146_ChIP-ChIP_HELA_Human2.36679742
13BMI1_23680149_ChIP-Seq_NPCS_Mouse2.35681418
14IGF1R_20145208_ChIP-Seq_DFB_Human2.32033460
15ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.29580451
16CBX2_27304074_Chip-Seq_ESCs_Mouse2.16089717
17MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.13522653
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.13376916
19ZFP57_27257070_Chip-Seq_ESCs_Mouse2.08259950
20TAF15_26573619_Chip-Seq_HEK293_Human2.06170589
21POU3F2_20337985_ChIP-ChIP_501MEL_Human2.03976492
22CTBP2_25329375_ChIP-Seq_LNCAP_Human1.97028354
23SALL1_21062744_ChIP-ChIP_HESCs_Human1.92066943
24ETS1_20019798_ChIP-Seq_JURKAT_Human1.88982752
25JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.86086050
26PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.85935834
27CTBP1_25329375_ChIP-Seq_LNCAP_Human1.85198833
28RNF2_27304074_Chip-Seq_NSC_Mouse1.78865231
29EWS_26573619_Chip-Seq_HEK293_Human1.77617718
30HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.76623957
31P300_19829295_ChIP-Seq_ESCs_Human1.76156743
32CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.73589616
33E2F4_17652178_ChIP-ChIP_JURKAT_Human1.72205307
34HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.70247506
35VDR_22108803_ChIP-Seq_LS180_Human1.69217179
36EED_16625203_ChIP-ChIP_MESCs_Mouse1.68642023
37EZH2_27304074_Chip-Seq_ESCs_Mouse1.65296405
38FOXM1_23109430_ChIP-Seq_U2OS_Human1.64912282
39MYC_18940864_ChIP-ChIP_HL60_Human1.63662044
40TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.61942982
41PCGF2_27294783_Chip-Seq_ESCs_Mouse1.60199984
42PADI4_21655091_ChIP-ChIP_MCF-7_Human1.57530635
43KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.55873825
44VDR_23849224_ChIP-Seq_CD4+_Human1.54161739
45ZNF274_21170338_ChIP-Seq_K562_Hela1.54053123
46JARID2_20064375_ChIP-Seq_MESCs_Mouse1.53386591
47CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.51220519
48SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.49964414
49TP63_19390658_ChIP-ChIP_HaCaT_Human1.49445149
50RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.48186017
51PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.45812102
52FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.43934590
53FLI1_27457419_Chip-Seq_LIVER_Mouse1.43626050
54TOP2B_26459242_ChIP-Seq_MCF-7_Human1.43563666
55MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.41483062
56REST_21632747_ChIP-Seq_MESCs_Mouse1.40869936
57PIAS1_25552417_ChIP-Seq_VCAP_Human1.40250320
58FOXP3_21729870_ChIP-Seq_TREG_Human1.39183176
59SMAD4_21799915_ChIP-Seq_A2780_Human1.39112111
60TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.38651346
61SOX2_16153702_ChIP-ChIP_HESCs_Human1.36541850
62POU5F1_16153702_ChIP-ChIP_HESCs_Human1.36313725
63SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.35849092
64TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.35410500
65POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.35410500
66MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.35194328
67GABP_19822575_ChIP-Seq_HepG2_Human1.34399601
68SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.33463760
69NANOG_18555785_Chip-Seq_ESCs_Mouse1.32345363
70FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.30617578
71E2F1_21310950_ChIP-Seq_MCF-7_Human1.29507463
72KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.29300322
73SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.29029986
74DCP1A_22483619_ChIP-Seq_HELA_Human1.28329980
75FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.27956754
76MYCN_18555785_ChIP-Seq_MESCs_Mouse1.27935451
77PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.27302890
78* SMAD3_21741376_ChIP-Seq_EPCs_Human1.26453093
79NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.26365868
80EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.25000313
81HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.24789870
82CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.24754920
83IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.24746622
84CBP_20019798_ChIP-Seq_JUKART_Human1.24746622
85HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.24365049
86SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.23805321
87ER_23166858_ChIP-Seq_MCF-7_Human1.23363952
88MYC_18555785_ChIP-Seq_MESCs_Mouse1.23155522
89NFE2_27457419_Chip-Seq_LIVER_Mouse1.20991780
90SUZ12_27294783_Chip-Seq_NPCs_Mouse1.19735001
91SRF_21415370_ChIP-Seq_HL-1_Mouse1.19417673
92* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.19379864
93JARID2_20075857_ChIP-Seq_MESCs_Mouse1.19361211
94P53_22387025_ChIP-Seq_ESCs_Mouse1.19341682
95YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.19156274
96E2F1_18555785_Chip-Seq_ESCs_Mouse1.16935967
97SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.15592668
98TTF2_22483619_ChIP-Seq_HELA_Human1.15509801
99KDM2B_26808549_Chip-Seq_REH_Human1.13824683
100* SOX9_26525672_Chip-Seq_HEART_Mouse1.12529195
101EST1_17652178_ChIP-ChIP_JURKAT_Human1.12312423
102NANOG_16153702_ChIP-ChIP_HESCs_Human1.12272373
103DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.11795608
104RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.11400496
105MYC_19030024_ChIP-ChIP_MESCs_Mouse1.10942115
106KLF5_20875108_ChIP-Seq_MESCs_Mouse1.10784926
107SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.10379317
108SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.10372040
109MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.09964654
110GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.09586005
111SUZ12_18555785_Chip-Seq_ESCs_Mouse1.09107577
112KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.09087448
113AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.06987871
114NOTCH1_21737748_ChIP-Seq_TLL_Human1.05580100
115OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05387637
116ELF1_17652178_ChIP-ChIP_JURKAT_Human1.04771385
117ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.04597474
118EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.04547270
119PCGF2_27294783_Chip-Seq_NPCs_Mouse1.03597471
120IRF1_19129219_ChIP-ChIP_H3396_Human1.02590843
121EZH2_27294783_Chip-Seq_ESCs_Mouse1.02104766
122EZH2_27294783_Chip-Seq_NPCs_Mouse1.02079088
123RNF2_27304074_Chip-Seq_ESCs_Mouse1.01700856
124CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.01410796
125NELFA_20434984_ChIP-Seq_ESCs_Mouse1.01297085
126YY1_21170310_ChIP-Seq_MESCs_Mouse1.01047128
127EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.00841388
128TCF4_23295773_ChIP-Seq_U87_Human1.00475545
129THAP11_20581084_ChIP-Seq_MESCs_Mouse1.00039351
130STAT3_18555785_Chip-Seq_ESCs_Mouse0.99601365
131JUN_21703547_ChIP-Seq_K562_Human0.99574126
132CMYC_18555785_Chip-Seq_ESCs_Mouse0.99015270
133PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.98970667
134E2F1_18555785_ChIP-Seq_MESCs_Mouse0.98940552
135STAT3_23295773_ChIP-Seq_U87_Human0.98527794
136P300_18555785_Chip-Seq_ESCs_Mouse0.98474938
137EZH2_18974828_ChIP-Seq_MESCs_Mouse0.95914216
138RNF2_18974828_ChIP-Seq_MESCs_Mouse0.95914216
139AR_21909140_ChIP-Seq_LNCAP_Human0.95288624
140CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95121112
141PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.92955163
142MYC_18358816_ChIP-ChIP_MESCs_Mouse0.92883704
143SOX2_18555785_ChIP-Seq_MESCs_Mouse0.92816340
144PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.92268295

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003123_paternal_imprinting3.65522259
2MP0001188_hyperpigmentation3.38577962
3MP0003787_abnormal_imprinting2.68022196
4MP0000566_synostosis2.66614627
5MP0003121_genomic_imprinting2.63272739
6MP0006292_abnormal_olfactory_placode2.63204204
7MP0003122_maternal_imprinting2.57190993
8MP0003941_abnormal_skin_development2.49244768
9MP0009697_abnormal_copulation2.42897249
10MP0005646_abnormal_pituitary_gland2.33262108
11MP0003890_abnormal_embryonic-extraembry2.11054270
12MP0002163_abnormal_gland_morphology2.04752860
13MP0006072_abnormal_retinal_apoptosis2.03853401
14MP0000631_abnormal_neuroendocrine_gland2.03545908
15MP0000678_abnormal_parathyroid_gland1.97042869
16MP0008877_abnormal_DNA_methylation1.96935033
17MP0005551_abnormal_eye_electrophysiolog1.95368242
18MP0003693_abnormal_embryo_hatching1.92974873
19MP0008789_abnormal_olfactory_epithelium1.91260975
20MP0001984_abnormal_olfaction1.89451840
21MP0010030_abnormal_orbit_morphology1.83351117
22MP0005394_taste/olfaction_phenotype1.72148244
23MP0005499_abnormal_olfactory_system1.72148244
24MP0001529_abnormal_vocalization1.63685957
25MP0005410_abnormal_fertilization1.63383246
26MP0002938_white_spotting1.62618128
27MP0003880_abnormal_central_pattern1.57711060
28MP0003136_yellow_coat_color1.57207938
29MP0003942_abnormal_urinary_system1.56966478
30MP0008057_abnormal_DNA_replication1.55708300
31MP0008932_abnormal_embryonic_tissue1.54149441
32MP0002751_abnormal_autonomic_nervous1.53521767
33MP0002822_catalepsy1.50764900
34MP0010094_abnormal_chromosome_stability1.49203456
35MP0006054_spinal_hemorrhage1.44718333
36MP0005171_absent_coat_pigmentation1.42217554
37MP0002234_abnormal_pharynx_morphology1.40498367
38MP0008058_abnormal_DNA_repair1.40146089
39MP0004859_abnormal_synaptic_plasticity1.39478913
40MP0002132_abnormal_respiratory_system1.37197684
41MP0005253_abnormal_eye_physiology1.36846528
42MP0000049_abnormal_middle_ear1.34916267
43MP0002127_abnormal_cardiovascular_syste1.32940443
44MP0003119_abnormal_digestive_system1.31635594
45MP0009379_abnormal_foot_pigmentation1.31553042
46MP0003718_maternal_effect1.29710494
47MP0005187_abnormal_penis_morphology1.28727433
48MP0002184_abnormal_innervation1.28528947
49MP0002233_abnormal_nose_morphology1.28447447
50MP0003111_abnormal_nucleus_morphology1.27421116
51MP0004043_abnormal_pH_regulation1.26866813
52MP0003786_premature_aging1.26303325
53MP0000516_abnormal_urinary_system1.24176309
54MP0005367_renal/urinary_system_phenotyp1.24176309
55MP0003698_abnormal_male_reproductive1.23480592
56MP0000026_abnormal_inner_ear1.23006581
57MP0005379_endocrine/exocrine_gland_phen1.22106008
58MP0004957_abnormal_blastocyst_morpholog1.22007832
59MP0002736_abnormal_nociception_after1.20911447
60MP0006276_abnormal_autonomic_nervous1.20816608
61MP0000372_irregular_coat_pigmentation1.19061941
62MP0003385_abnormal_body_wall1.18595212
63MP0005645_abnormal_hypothalamus_physiol1.16937707
64MP0003115_abnormal_respiratory_system1.15330883
65MP0000647_abnormal_sebaceous_gland1.15022861
66MP0002638_abnormal_pupillary_reflex1.14038793
67MP0004270_analgesia1.13770469
68MP0002653_abnormal_ependyma_morphology1.12262000
69MP0003938_abnormal_ear_development1.11266723
70MP0002735_abnormal_chemical_nociception1.09989679
71MP0001968_abnormal_touch/_nociception1.08454461
72MP0006035_abnormal_mitochondrial_morpho1.07763230
73MP0000534_abnormal_ureter_morphology1.06955567
74MP0001293_anophthalmia1.05219604
75MP0004885_abnormal_endolymph1.04009268
76MP0004233_abnormal_muscle_weight1.03536555
77MP0005248_abnormal_Harderian_gland1.03249361
78MP0001486_abnormal_startle_reflex1.02395437
79MP0002272_abnormal_nervous_system1.02111689
80MP0004142_abnormal_muscle_tone1.01511956
81MP0002249_abnormal_larynx_morphology1.01315847
82MP0005377_hearing/vestibular/ear_phenot1.00053239
83MP0003878_abnormal_ear_physiology1.00053239
84MP0002557_abnormal_social/conspecific_i0.98921661
85MP0001177_atelectasis0.98628690
86MP0004133_heterotaxia0.98379849
87MP0002210_abnormal_sex_determination0.97479592
88MP0005423_abnormal_somatic_nervous0.97344341
89MP0002102_abnormal_ear_morphology0.96591743
90MP0009046_muscle_twitch0.95224599
91MP0004215_abnormal_myocardial_fiber0.94865413
92MP0003567_abnormal_fetal_cardiomyocyte0.94597566
93MP0001299_abnormal_eye_distance/0.94153570
94MP0000778_abnormal_nervous_system0.94046717
95MP0001963_abnormal_hearing_physiology0.93817104
96MP0002734_abnormal_mechanical_nocicepti0.93017792
97MP0001324_abnormal_eye_pigmentation0.92751282
98MP0001286_abnormal_eye_development0.92550586
99MP0009250_abnormal_appendicular_skeleto0.92479107
100MP0002882_abnormal_neuron_morphology0.92187168
101MP0005174_abnormal_tail_pigmentation0.92180382
102MP0004811_abnormal_neuron_physiology0.92001475
103MP0002152_abnormal_brain_morphology0.91852517
104MP0002572_abnormal_emotion/affect_behav0.91525947
105MP0003937_abnormal_limbs/digits/tail_de0.91113879
106MP0004084_abnormal_cardiac_muscle0.91092700
107MP0002282_abnormal_trachea_morphology0.90924964
108MP0003315_abnormal_perineum_morphology0.90626961
109MP0001929_abnormal_gametogenesis0.90548676
110MP0003635_abnormal_synaptic_transmissio0.90413331
111MP0000955_abnormal_spinal_cord0.90155505
112MP0004147_increased_porphyrin_level0.90058467
113MP0001485_abnormal_pinna_reflex0.89210835
114MP0002095_abnormal_skin_pigmentation0.89085939
115MP0002064_seizures0.86287918
116MP0000569_abnormal_digit_pigmentation0.86139816
117MP0002067_abnormal_sensory_capabilities0.85575861
118MP0004085_abnormal_heartbeat0.85493195
119MP0003935_abnormal_craniofacial_develop0.85178030
120MP0002063_abnormal_learning/memory/cond0.83835244
121MP0009780_abnormal_chondrocyte_physiolo0.82721678
122MP0005195_abnormal_posterior_eye0.82111227
123MP0003755_abnormal_palate_morphology0.80915270
124MP0003879_abnormal_hair_cell0.80471791
125MP0003861_abnormal_nervous_system0.79534644
126MP0002116_abnormal_craniofacial_bone0.79485878
127MP0004742_abnormal_vestibular_system0.79392249
128MP0008004_abnormal_stomach_pH0.79101301
129MP0010386_abnormal_urinary_bladder0.78470825
130MP0002752_abnormal_somatic_nervous0.77733803
131MP0009053_abnormal_anal_canal0.77381778
132MP0003077_abnormal_cell_cycle0.77174120
133MP0005391_vision/eye_phenotype0.76949331
134MP0001502_abnormal_circadian_rhythm0.75743574
135MP0009745_abnormal_behavioral_response0.75603138
136MP0002090_abnormal_vision0.75466569
137MP0000537_abnormal_urethra_morphology0.74411496

Predicted human phenotypes

RankGene SetZ-score
1Absent eyebrow (HP:0002223)4.77847602
2Nephrogenic diabetes insipidus (HP:0009806)4.04838854
3Chronic bronchitis (HP:0004469)3.91480020
4Medial flaring of the eyebrow (HP:0010747)3.70751764
5Gait imbalance (HP:0002141)3.66378453
6Congenital primary aphakia (HP:0007707)3.61402973
7Decreased circulating renin level (HP:0003351)3.53504257
8Dynein arm defect of respiratory motile cilia (HP:0012255)3.44324126
9Absent/shortened dynein arms (HP:0200106)3.44324126
10Absent eyelashes (HP:0000561)3.39084657
11Vaginal atresia (HP:0000148)3.33726892
12Chromosomal breakage induced by crosslinking agents (HP:0003221)3.27262675
13Genital tract atresia (HP:0001827)3.26418249
14Cortical dysplasia (HP:0002539)3.19814859
15Poor coordination (HP:0002370)3.15897354
16Chromsome breakage (HP:0040012)3.09600596
17Abnormality of the labia minora (HP:0012880)2.95370637
18Hepatoblastoma (HP:0002884)2.94854553
19Chronic hepatic failure (HP:0100626)2.90521604
20True hermaphroditism (HP:0010459)2.89523678
21Nephronophthisis (HP:0000090)2.85219124
22Bifid tongue (HP:0010297)2.76138841
23Congenital stationary night blindness (HP:0007642)2.73991744
24Abnormal hair whorl (HP:0010721)2.65449318
25Abnormality of the ileum (HP:0001549)2.65348603
26Facial cleft (HP:0002006)2.62854872
27Lissencephaly (HP:0001339)2.57761539
28Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.56925997
29Volvulus (HP:0002580)2.55247090
30Abnormal respiratory motile cilium morphology (HP:0005938)2.51477208
31Abnormal respiratory epithelium morphology (HP:0012253)2.51477208
32Hyperactive renin-angiotensin system (HP:0000841)2.46553328
33Decreased central vision (HP:0007663)2.46263737
34Abnormal ciliary motility (HP:0012262)2.43231677
35Nephroblastoma (Wilms tumor) (HP:0002667)2.42357334
36Abnormality of the right ventricle (HP:0001707)2.41314731
37Abnormal respiratory motile cilium physiology (HP:0012261)2.40884493
38Drooling (HP:0002307)2.40104321
39Supernumerary spleens (HP:0009799)2.38182005
40Abnormal pancreas size (HP:0012094)2.35093723
41Retinal dysplasia (HP:0007973)2.33965596
42Osteomalacia (HP:0002749)2.33858059
43Abnormality of chromosome stability (HP:0003220)2.33039668
44Acute encephalopathy (HP:0006846)2.32827448
45Colon cancer (HP:0003003)2.32775578
46Abnormality of the renal medulla (HP:0100957)2.32194010
47Embryonal renal neoplasm (HP:0011794)2.30900002
48Pancreatic fibrosis (HP:0100732)2.30467872
49Tubulointerstitial nephritis (HP:0001970)2.30463017
50Acute necrotizing encephalopathy (HP:0006965)2.26421914
51Preaxial hand polydactyly (HP:0001177)2.24667988
52Duodenal stenosis (HP:0100867)2.23913435
53Small intestinal stenosis (HP:0012848)2.23913435
54Morphological abnormality of the middle ear (HP:0008609)2.22575644
55Absent hair (HP:0002298)2.21612415
56Hyperaldosteronism (HP:0000859)2.21125012
57Diastasis recti (HP:0001540)2.21116909
58Abnormality of midbrain morphology (HP:0002418)2.21112628
59Molar tooth sign on MRI (HP:0002419)2.21112628
60Conjugated hyperbilirubinemia (HP:0002908)2.20819146
61Abnormality of the duodenum (HP:0002246)2.19728163
62Abnormality of the nasolacrimal system (HP:0000614)2.17953614
63Hyperventilation (HP:0002883)2.17042483
64Aplasia/Hypoplasia of the lens (HP:0008063)2.16704052
65Pendular nystagmus (HP:0012043)2.13232188
66Adrenal hypoplasia (HP:0000835)2.12002340
67Aplasia/Hypoplasia of the tibia (HP:0005772)2.09862833
68Abnormality of the lacrimal duct (HP:0011481)2.09413952
69Sclerocornea (HP:0000647)2.09251678
70Excessive salivation (HP:0003781)2.08776988
71Short tibia (HP:0005736)2.08602656
72Thyroid-stimulating hormone excess (HP:0002925)2.08546515
73Sloping forehead (HP:0000340)2.07814824
74Abnormal lung lobation (HP:0002101)2.07809703
75Postaxial foot polydactyly (HP:0001830)2.04885663
76Astigmatism (HP:0000483)2.02591529
77Postaxial hand polydactyly (HP:0001162)2.02545368
78Abnormal mitochondria in muscle tissue (HP:0008316)2.02097728
79Hepatocellular necrosis (HP:0001404)2.01705725
80Abnormality of the metopic suture (HP:0005556)2.01430175
81Cutaneous finger syndactyly (HP:0010554)2.00775779
82Oligodactyly (HP:0012165)1.99938169
83Aplasia/Hypoplasia of the tongue (HP:0010295)1.99320246
84Occipital encephalocele (HP:0002085)1.98013276
85Oligodactyly (hands) (HP:0001180)1.97770508
86Ectopic anus (HP:0004397)1.97148598
87Aganglionic megacolon (HP:0002251)1.96386919
88Midline defect of the nose (HP:0004122)1.96103937
89Ectopic kidney (HP:0000086)1.95415298
90Progressive macrocephaly (HP:0004481)1.94917077
91Dandy-Walker malformation (HP:0001305)1.94631197
92Aplasia/Hypoplasia of the sternum (HP:0006714)1.94017893
93Epileptic encephalopathy (HP:0200134)1.93171497
94Increased CSF lactate (HP:0002490)1.92972252
95Labial hypoplasia (HP:0000066)1.92528622
96Aplasia/Hypoplasia of the uvula (HP:0010293)1.92241098
97Septo-optic dysplasia (HP:0100842)1.91630950
98Mitochondrial inheritance (HP:0001427)1.91393351
99Triphalangeal thumb (HP:0001199)1.91068410
100Hyperkalemia (HP:0002153)1.90347520
101Anencephaly (HP:0002323)1.90329788
102Patellar aplasia (HP:0006443)1.90072871
103Focal motor seizures (HP:0011153)1.89198140
104Pancreatic cysts (HP:0001737)1.89043980
105Type II lissencephaly (HP:0007260)1.87673737
106Broad foot (HP:0001769)1.86396317
107Rhinitis (HP:0012384)1.85738114
108Anophthalmia (HP:0000528)1.84936718
109Abnormality of the carotid arteries (HP:0005344)1.84475924
110Renal hypoplasia (HP:0000089)1.84115922
111Hypoplastic female external genitalia (HP:0012815)1.83119447
112Cutaneous syndactyly (HP:0012725)1.82741639
113Broad-based gait (HP:0002136)1.82511933
114Hypokalemic alkalosis (HP:0001949)1.82151428
115Growth hormone deficiency (HP:0000824)1.82132218
116Cerebellar dysplasia (HP:0007033)1.81043844
117Hypoplastic pelvis (HP:0008839)1.80925502
118Renal salt wasting (HP:0000127)1.80667237
119Renal dysplasia (HP:0000110)1.78760565
120Dental crowding (HP:0000678)1.78069370
121Narrow forehead (HP:0000341)1.77995183
122Aplasia/Hypoplasia of the patella (HP:0006498)1.77965847
123Optic nerve hypoplasia (HP:0000609)1.77164277
124Renal duplication (HP:0000075)1.73746551
125Abnormality of glycolysis (HP:0004366)1.72101400
126Ependymoma (HP:0002888)1.71928404
127Multicystic kidney dysplasia (HP:0000003)1.70982410
128Chorioretinal atrophy (HP:0000533)1.70503704
129Aplasia/Hypoplasia of the fovea (HP:0008060)1.70237848
130Hypoplasia of the fovea (HP:0007750)1.70237848
131Papillary thyroid carcinoma (HP:0002895)1.70018440
132Hyperglycinemia (HP:0002154)1.69625048
133Increased serum pyruvate (HP:0003542)1.69498553
134CNS hypomyelination (HP:0003429)1.68776903
135Astrocytoma (HP:0009592)1.68207844
136Abnormality of the astrocytes (HP:0100707)1.68207844
137Abnormality of the fovea (HP:0000493)1.67706473
138Abnormality of the anterior horn cell (HP:0006802)1.67505406
139Degeneration of anterior horn cells (HP:0002398)1.67505406
140Postnatal microcephaly (HP:0005484)1.66615730
141Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.66167672
142Abnormality of the preputium (HP:0100587)1.64888895
143Limb dystonia (HP:0002451)1.64122564
144Skull defect (HP:0001362)1.63806089
145Aqueductal stenosis (HP:0002410)1.63742258
146Absent speech (HP:0001344)1.63389480
147Cleft eyelid (HP:0000625)1.63290985
148Aplasia/Hypoplasia of the sacrum (HP:0008517)1.63269976
149Gastrointestinal atresia (HP:0002589)1.62510004
150Polymicrogyria (HP:0002126)1.62344678
151Abnormality of the lower motor neuron (HP:0002366)1.62032315
152Microvesicular hepatic steatosis (HP:0001414)1.61985886
153Abnormality of chloride homeostasis (HP:0011422)1.60948533
154Left ventricular hypertrophy (HP:0001712)1.59403686
155Specific learning disability (HP:0001328)1.59109079
156Intestinal atresia (HP:0011100)1.58157243
157Hypoplasia of the capital femoral epiphysis (HP:0003090)1.57807616
158Hypoplastic labia majora (HP:0000059)1.57567039
159Hypothermia (HP:0002045)1.57486973
160Embryonal neoplasm (HP:0002898)1.56997470
161Hyponatremia (HP:0002902)1.56844979
162Short foot (HP:0001773)1.56786781
163Meckel diverticulum (HP:0002245)1.56478123
164Optic disc pallor (HP:0000543)1.55485266

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.95187566
2LATS13.86554587
3AKT33.82036831
4STK38L3.01821505
5TRIM282.94092256
6MAP4K22.81311407
7TAOK22.50610691
8LMTK22.34060460
9SIK32.31929047
10SRPK12.30751594
11PLK32.11343434
12MKNK22.04363018
13PASK1.97551770
14MKNK11.81523128
15BRSK21.80021177
16MAP2K71.78359090
17YES11.78071957
18VRK21.77187777
19OBSCN1.76942432
20PDK31.73204130
21PDK41.73204130
22ERBB31.68811605
23CDC71.67800486
24MAP3K41.65594653
25SGK21.63538682
26MAP3K121.60575866
27NEK21.56637574
28ACVR1B1.56246236
29PLK21.52890660
30VRK11.52074573
31PRKD31.51794367
32NTRK31.45223103
33IRAK21.41229349
34CHEK21.39810540
35EIF2AK11.38368045
36PNCK1.35902648
37NME11.31817615
38CSNK1G31.28568798
39CSNK1G21.28483897
40PBK1.25503279
41NEK11.23902236
42INSRR1.23588731
43BRAF1.21601753
44DAPK21.21401027
45PLK41.20085396
46CSNK1G11.19913914
47TSSK61.18391704
48CSNK1A1L1.18020567
49BRSK11.17371358
50IRAK11.16955360
51CCNB11.15918819
52PRPF4B1.12619677
53TTK1.10068913
54ZAK1.06642629
55TNIK1.04862374
56MYLK1.02555134
57TGFBR11.01852903
58FRK1.00755856
59SIK20.99475497
60STK160.96661417
61PAK30.96641191
62EPHB20.95231748
63KSR10.94246649
64SGK4940.93514614
65SGK2230.93514614
66PDK20.93330633
67CDK30.91827900
68BCR0.91236301
69BCKDK0.90960005
70NTRK20.88315404
71MAPK130.88060127
72PLK10.87604016
73TAF10.87207460
74STK30.82628066
75EIF2AK20.81141171
76DYRK1A0.80374046
77STK240.80138727
78BMPR1B0.79511801
79MARK10.78622935
80MINK10.77910548
81SGK30.76281005
82WEE10.75107892
83DAPK10.73413702
84MARK30.72380688
85MAP3K30.71891487
86EIF2AK30.71536158
87CDC42BPA0.70167524
88CDK80.67306609
89PAK60.66568499
90WNK30.66011810
91AURKB0.65743605
92PINK10.63900911
93CHEK10.60940119
94BUB10.58459966
95ADRBK20.56800106
96CAMK1D0.56281726
97UHMK10.55887175
98ATR0.55676306
99CAMK40.54514518
100ATM0.53967392
101LIMK10.52829864
102WNK40.51756498
103OXSR10.50350673
104CAMKK20.49532931
105GRK70.47362544
106ADRBK10.46844762
107CDK140.46807077
108CAMK10.45024517
109STK390.44813401
110NUAK10.44262066
111DYRK30.44163531
112PKN10.44042138
113CDK180.43977754
114FGFR10.43123771
115CAMK2A0.42259353
116CSNK2A10.40115958
117PTK2B0.39467315
118CAMK1G0.39258597
119EPHA40.39073696
120TIE10.37430491
121DYRK20.37288254
122PRKG10.36644103
123CDK10.36405816
124ERBB40.36386548
125PRKCG0.34854633
126CDK11A0.34394819
127CSNK1E0.34368391
128CDK150.34097887
129AURKA0.33863897
130CDK70.33665065
131GRK10.33166030
132CSNK1A10.32654618
133PRKDC0.32245453
134RPS6KA40.31336894
135PRKG20.31202693
136CDK190.30364890
137PRKCE0.30328268
138PRKACA0.28858356
139PIK3CA0.28412503
140PRKCB0.28130079

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.53436661
2Mismatch repair_Homo sapiens_hsa034302.84249908
3Homologous recombination_Homo sapiens_hsa034402.64106053
4Fanconi anemia pathway_Homo sapiens_hsa034602.58812367
5DNA replication_Homo sapiens_hsa030302.41507531
6Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.17495397
7Fatty acid elongation_Homo sapiens_hsa000622.14332015
8Oxidative phosphorylation_Homo sapiens_hsa001902.11431788
9Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.10622595
10Huntingtons disease_Homo sapiens_hsa050162.10100292
11Parkinsons disease_Homo sapiens_hsa050122.01148670
12One carbon pool by folate_Homo sapiens_hsa006702.00382254
13Basal transcription factors_Homo sapiens_hsa030221.96586120
14Propanoate metabolism_Homo sapiens_hsa006401.95551041
15Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.95075363
16Cell cycle_Homo sapiens_hsa041101.91514428
17Steroid biosynthesis_Homo sapiens_hsa001001.86169360
18Taste transduction_Homo sapiens_hsa047421.76214277
19Base excision repair_Homo sapiens_hsa034101.75346386
20Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.74740890
21Morphine addiction_Homo sapiens_hsa050321.74504869
22Synaptic vesicle cycle_Homo sapiens_hsa047211.71820871
23Cardiac muscle contraction_Homo sapiens_hsa042601.71194416
24Pyrimidine metabolism_Homo sapiens_hsa002401.70624256
25Spliceosome_Homo sapiens_hsa030401.66310845
26Nucleotide excision repair_Homo sapiens_hsa034201.64338919
27Protein export_Homo sapiens_hsa030601.61366930
28RNA degradation_Homo sapiens_hsa030181.60408115
29RNA transport_Homo sapiens_hsa030131.56666140
30Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.49057531
31GABAergic synapse_Homo sapiens_hsa047271.48850384
32Purine metabolism_Homo sapiens_hsa002301.46727583
33Ribosome_Homo sapiens_hsa030101.46476354
34Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.45187369
35Insulin secretion_Homo sapiens_hsa049111.43298854
36Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.41380576
37RNA polymerase_Homo sapiens_hsa030201.41324045
38Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.39542729
39Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.37145213
40Alzheimers disease_Homo sapiens_hsa050101.35918119
41Butanoate metabolism_Homo sapiens_hsa006501.35798286
42Phototransduction_Homo sapiens_hsa047441.32086927
43Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.29887437
44Cysteine and methionine metabolism_Homo sapiens_hsa002701.28311824
45Oocyte meiosis_Homo sapiens_hsa041141.26507086
46Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.26501226
47Maturity onset diabetes of the young_Homo sapiens_hsa049501.25763080
48Proteasome_Homo sapiens_hsa030501.22782170
49Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.22596763
50Selenocompound metabolism_Homo sapiens_hsa004501.21214731
51Amphetamine addiction_Homo sapiens_hsa050311.14844227
52mRNA surveillance pathway_Homo sapiens_hsa030151.14617466
53Collecting duct acid secretion_Homo sapiens_hsa049661.13264539
54Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.12852627
55Serotonergic synapse_Homo sapiens_hsa047261.12184703
56Basal cell carcinoma_Homo sapiens_hsa052171.11708767
57Olfactory transduction_Homo sapiens_hsa047401.11351971
58Circadian entrainment_Homo sapiens_hsa047131.11096683
59Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.99027078
602-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.98558836
61SNARE interactions in vesicular transport_Homo sapiens_hsa041300.96686757
62Hedgehog signaling pathway_Homo sapiens_hsa043400.96225574
63Vibrio cholerae infection_Homo sapiens_hsa051100.92963131
64Alcoholism_Homo sapiens_hsa050340.92802292
65Peroxisome_Homo sapiens_hsa041460.91616948
66Melanoma_Homo sapiens_hsa052180.91588600
67Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.91491465
68Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.90845685
69Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.87708852
70Circadian rhythm_Homo sapiens_hsa047100.87532312
71Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.87041162
72Non-homologous end-joining_Homo sapiens_hsa034500.83168290
73Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.82562901
74Glutamatergic synapse_Homo sapiens_hsa047240.80337566
75Fatty acid metabolism_Homo sapiens_hsa012120.79987091
76Ether lipid metabolism_Homo sapiens_hsa005650.79889924
77Pyruvate metabolism_Homo sapiens_hsa006200.78625669
78Regulation of autophagy_Homo sapiens_hsa041400.75566954
79Dilated cardiomyopathy_Homo sapiens_hsa054140.75281834
80Cocaine addiction_Homo sapiens_hsa050300.74500954
81Wnt signaling pathway_Homo sapiens_hsa043100.74488210
82Glucagon signaling pathway_Homo sapiens_hsa049220.73892535
83Hippo signaling pathway_Homo sapiens_hsa043900.73177932
84Dopaminergic synapse_Homo sapiens_hsa047280.72802607
85Axon guidance_Homo sapiens_hsa043600.71301971
86Long-term potentiation_Homo sapiens_hsa047200.70101402
87Folate biosynthesis_Homo sapiens_hsa007900.69818975
88Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.69778045
89Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.69742626
90Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.69384178
91Thyroid cancer_Homo sapiens_hsa052160.67717380
92Biosynthesis of amino acids_Homo sapiens_hsa012300.67066374
93Calcium signaling pathway_Homo sapiens_hsa040200.63861571
94Lysine degradation_Homo sapiens_hsa003100.62763939
95Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.60193739
96Long-term depression_Homo sapiens_hsa047300.59530179
97Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.59463251
98Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.58253293
99Carbon metabolism_Homo sapiens_hsa012000.58179700
100N-Glycan biosynthesis_Homo sapiens_hsa005100.55926908
101Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.55664161
102Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.53812907
103Melanogenesis_Homo sapiens_hsa049160.53189543
104Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.52814673
105Renin secretion_Homo sapiens_hsa049240.52542610
106beta-Alanine metabolism_Homo sapiens_hsa004100.51808316
107Phenylalanine metabolism_Homo sapiens_hsa003600.50763738
108Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.50732696
109Caffeine metabolism_Homo sapiens_hsa002320.50061727
110ErbB signaling pathway_Homo sapiens_hsa040120.49957630
111TGF-beta signaling pathway_Homo sapiens_hsa043500.49596242
112Chemical carcinogenesis_Homo sapiens_hsa052040.49491200
113Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.46937191
114Prostate cancer_Homo sapiens_hsa052150.46511260
115Primary bile acid biosynthesis_Homo sapiens_hsa001200.45571819
116Fructose and mannose metabolism_Homo sapiens_hsa000510.44866096
117Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.44351247
118Cholinergic synapse_Homo sapiens_hsa047250.43509854
119Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.43295774
120HTLV-I infection_Homo sapiens_hsa051660.43152708
121Glutathione metabolism_Homo sapiens_hsa004800.40945268
122Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.40795838
123Linoleic acid metabolism_Homo sapiens_hsa005910.40497083
124cGMP-PKG signaling pathway_Homo sapiens_hsa040220.40441460
125Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.39850113
126p53 signaling pathway_Homo sapiens_hsa041150.39224305
127Fatty acid degradation_Homo sapiens_hsa000710.37817943
128Metabolic pathways_Homo sapiens_hsa011000.37670889
129Nitrogen metabolism_Homo sapiens_hsa009100.37551391
130Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.35242490
131Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.33913676
132Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.33207885
133Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.33204609
134Central carbon metabolism in cancer_Homo sapiens_hsa052300.32882179
135Steroid hormone biosynthesis_Homo sapiens_hsa001400.32852437
136Colorectal cancer_Homo sapiens_hsa052100.31589655
137Arginine and proline metabolism_Homo sapiens_hsa003300.31392478
138Tryptophan metabolism_Homo sapiens_hsa003800.30669244
139Sulfur relay system_Homo sapiens_hsa041220.30641589
140Epstein-Barr virus infection_Homo sapiens_hsa051690.30354162

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »