PCP4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cerebellar Purkinje cell layer development (GO:0021680)6.70497004
2fructose metabolic process (GO:0006000)6.15035862
3protein heterotetramerization (GO:0051290)6.00976059
4metanephric tubule development (GO:0072170)5.95594590
5metanephric nephron tubule development (GO:0072234)5.95594590
6C4-dicarboxylate transport (GO:0015740)5.87176440
7cellular potassium ion homeostasis (GO:0030007)5.82991326
8cell differentiation in hindbrain (GO:0021533)5.66108977
9positive regulation of phosphoprotein phosphatase activity (GO:0032516)5.56667766
10neurofilament cytoskeleton organization (GO:0060052)5.53518948
11synaptic vesicle exocytosis (GO:0016079)5.52230342
12positive regulation of synaptic transmission, GABAergic (GO:0032230)5.49287365
13collecting duct development (GO:0072044)5.45027156
14metanephric nephron epithelium development (GO:0072243)5.41821223
15cellular sodium ion homeostasis (GO:0006883)5.41674109
16neuronal action potential propagation (GO:0019227)5.23516305
17regulation of short-term neuronal synaptic plasticity (GO:0048172)5.15792216
18inositol phosphate-mediated signaling (GO:0048016)5.05629631
19musculoskeletal movement (GO:0050881)4.96316448
20multicellular organismal movement (GO:0050879)4.96316448
21metanephric epithelium development (GO:0072207)4.96078569
22retina layer formation (GO:0010842)4.94302863
23positive regulation of muscle hypertrophy (GO:0014742)4.94150566
24positive regulation of cardiac muscle hypertrophy (GO:0010613)4.94150566
25vocalization behavior (GO:0071625)4.80736112
26mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.78728387
27locomotory exploration behavior (GO:0035641)4.68589679
28behavioral response to nicotine (GO:0035095)4.67080878
29regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)4.66279180
30aggressive behavior (GO:0002118)4.60440350
31sodium ion export (GO:0071436)4.58670666
32neuron cell-cell adhesion (GO:0007158)4.53292245
33glutamate secretion (GO:0014047)4.51196937
34relaxation of smooth muscle (GO:0044557)4.49942666
35positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.48337822
36regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.46478886
37energy coupled proton transport, down electrochemical gradient (GO:0015985)4.42579985
38ATP synthesis coupled proton transport (GO:0015986)4.42579985
39synaptic vesicle maturation (GO:0016188)4.41908932
40positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.38494400
41regulation of synaptic vesicle exocytosis (GO:2000300)4.36274264
42regulation of glutamate receptor signaling pathway (GO:1900449)4.23750072
43mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.20506336
44positive regulation of amino acid transport (GO:0051957)4.17379666
45protein localization to synapse (GO:0035418)4.17216287
46positive regulation of glomerulus development (GO:0090193)4.12055945
47retinal cone cell development (GO:0046549)4.11188726
48synaptic transmission, dopaminergic (GO:0001963)4.08900247
49negative regulation of heart rate (GO:0010459)4.06280477
50neurotransmitter secretion (GO:0007269)4.04337482
51chemosensory behavior (GO:0007635)4.00991429
52neuron-neuron synaptic transmission (GO:0007270)3.98409863
53respiratory electron transport chain (GO:0022904)3.92358345
54regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.88609238
55dopamine biosynthetic process (GO:0042416)3.87472768
56regulation of synaptic vesicle transport (GO:1902803)3.83782939
57electron transport chain (GO:0022900)3.83758639
58regulation of synapse structural plasticity (GO:0051823)3.83619262
59ionotropic glutamate receptor signaling pathway (GO:0035235)3.79629574
60striatum development (GO:0021756)3.78976525
61auditory receptor cell stereocilium organization (GO:0060088)3.78019733
62negative regulation of norepinephrine secretion (GO:0010700)3.77919674
63exploration behavior (GO:0035640)3.77485593
64positive regulation of dendritic spine morphogenesis (GO:0061003)3.75614402
65innervation (GO:0060384)3.70939854
66behavioral response to cocaine (GO:0048148)3.70525465
67prepulse inhibition (GO:0060134)3.69604792
68relaxation of cardiac muscle (GO:0055119)3.68895391
69glutamate receptor signaling pathway (GO:0007215)3.68865849
70regulation of long-term neuronal synaptic plasticity (GO:0048169)3.65030920
71regulation of potassium ion transmembrane transporter activity (GO:1901016)3.63750161
72regulation of neuronal synaptic plasticity (GO:0048168)3.61960644
73energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.60788840
74ATP hydrolysis coupled proton transport (GO:0015991)3.60788840
75synaptic transmission, glutamatergic (GO:0035249)3.58401507
76synaptic vesicle docking involved in exocytosis (GO:0016081)3.58369524
77cerebellar Purkinje cell differentiation (GO:0021702)3.56827301
78transmission of nerve impulse (GO:0019226)3.55086685
79neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)3.54282777
80serotonin metabolic process (GO:0042428)3.52847470
81gamma-aminobutyric acid signaling pathway (GO:0007214)3.52712991
82endoplasmic reticulum calcium ion homeostasis (GO:0032469)3.51823714
83nephron tubule development (GO:0072080)3.49250145
84long-term synaptic potentiation (GO:0060291)3.49083114
85potassium ion homeostasis (GO:0055075)3.48663536
86long term synaptic depression (GO:0060292)3.45907102
87regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.44874759
88regulation of glutamate secretion (GO:0014048)3.42556224
89G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.41495620
90regulation of protein kinase A signaling (GO:0010738)3.41087516
91membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.40742448
92cGMP metabolic process (GO:0046068)3.40137015
93neurotransmitter transport (GO:0006836)3.39933144
94neuron recognition (GO:0008038)3.39276347
95relaxation of muscle (GO:0090075)3.38796258
96response to histamine (GO:0034776)3.38203849
97parturition (GO:0007567)3.37803508
98regulation of potassium ion transmembrane transport (GO:1901379)3.36720043
99chaperone-mediated protein transport (GO:0072321)3.36530453
100positive regulation of potassium ion transmembrane transport (GO:1901381)3.35693241
101regulation of excitatory postsynaptic membrane potential (GO:0060079)3.34793936
102neuromuscular process controlling posture (GO:0050884)3.31238873
103positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.30908441
104proline transport (GO:0015824)3.30622976
105regulation of voltage-gated calcium channel activity (GO:1901385)3.30008801
106regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.29228298
107regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.29228298
108negative regulation of dendrite morphogenesis (GO:0050774)3.28523523
109detection of calcium ion (GO:0005513)3.25786892
110synaptic vesicle endocytosis (GO:0048488)3.25521933
111gamma-aminobutyric acid transport (GO:0015812)3.25220055
112hydrogen ion transmembrane transport (GO:1902600)3.23845395
113negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.22595523
114mating behavior (GO:0007617)3.22382994
115G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.22169967
116long-term memory (GO:0007616)3.21854384
117cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.21495543
118regulation of neurotransmitter levels (GO:0001505)3.21287639
119neurotransmitter-gated ion channel clustering (GO:0072578)3.20383018
120regulation of postsynaptic membrane potential (GO:0060078)3.18286129
121regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.17737056
122G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.16526226
123adult walking behavior (GO:0007628)3.16191612
124activation of protein kinase A activity (GO:0034199)3.15949904
125renal tubule development (GO:0061326)3.15034458
126regulation of neurotransmitter secretion (GO:0046928)3.14058866
127regulation of vesicle fusion (GO:0031338)3.13819959
128negative regulation of fatty acid transport (GO:2000192)3.13324792
129nitric oxide biosynthetic process (GO:0006809)3.13310065
130regulation of amine transport (GO:0051952)3.12978909
131cerebellar granule cell differentiation (GO:0021707)3.12491523
132calcium-mediated signaling using intracellular calcium source (GO:0035584)3.11409653
133negative regulation of synaptic transmission, GABAergic (GO:0032229)3.10056232
134layer formation in cerebral cortex (GO:0021819)3.09138565
135regulation of synaptic plasticity (GO:0048167)3.09010428
136regulation of dopamine secretion (GO:0014059)3.08220724
137endocrine hormone secretion (GO:0060986)3.06650527
138primary amino compound metabolic process (GO:1901160)3.06387664
139sodium ion homeostasis (GO:0055078)3.06350148
140regulation of synaptic transmission, glutamatergic (GO:0051966)3.05269001
141positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.04921933
142regulation of dopamine metabolic process (GO:0042053)3.04837442
143regulation of catecholamine metabolic process (GO:0042069)3.04837442
144positive regulation of membrane potential (GO:0045838)3.04259907
145axonal fasciculation (GO:0007413)3.03454576
146regulation of neurotransmitter transport (GO:0051588)3.03033457
147behavioral defense response (GO:0002209)3.02268531
148behavioral fear response (GO:0001662)3.02268531
149response to ammonium ion (GO:0060359)3.00336634
150presynaptic membrane organization (GO:0097090)2.98884448
151negative regulation of catecholamine secretion (GO:0033604)2.98771213
152membrane depolarization (GO:0051899)2.96806029
153membrane hyperpolarization (GO:0060081)2.96398413
154inner ear receptor stereocilium organization (GO:0060122)2.95246883
155activation of protein kinase B activity (GO:0032148)2.93886380
156membrane depolarization during action potential (GO:0086010)2.92145548
157synaptic transmission (GO:0007268)2.91659169
158acidic amino acid transport (GO:0015800)2.90871754
159negative regulation of dendrite development (GO:2000171)2.90454686
160positive regulation of neurotransmitter transport (GO:0051590)2.90300629
161regulation of neurotransmitter uptake (GO:0051580)2.89786261
162transferrin transport (GO:0033572)2.89262199
163urinary tract smooth muscle contraction (GO:0014848)2.89226579
164cell migration in hindbrain (GO:0021535)2.88855939
165fear response (GO:0042596)2.88761363
166presynaptic membrane assembly (GO:0097105)2.88196135
167positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.88093343
168response to amphetamine (GO:0001975)2.86441676
169short-term memory (GO:0007614)10.0947257

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.94548272
2GBX2_23144817_ChIP-Seq_PC3_Human3.73489163
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.40948973
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.32814628
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.24237669
6JARID2_20075857_ChIP-Seq_MESCs_Mouse2.91059839
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.82912315
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.82912315
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.81170996
10TAF15_26573619_Chip-Seq_HEK293_Human2.78839588
11REST_21632747_ChIP-Seq_MESCs_Mouse2.77202224
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.75570654
13SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.60886757
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.60350547
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.59269188
16RARB_27405468_Chip-Seq_BRAIN_Mouse2.56847535
17EZH2_27304074_Chip-Seq_ESCs_Mouse2.56747080
18RBPJ_22232070_ChIP-Seq_NCS_Mouse2.48031733
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.40507681
20* CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.38791389
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.27157366
22NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.23761298
23REST_18959480_ChIP-ChIP_MESCs_Mouse2.22537484
24EZH2_27294783_Chip-Seq_ESCs_Mouse2.19823598
25CTBP2_25329375_ChIP-Seq_LNCAP_Human2.13405935
26DROSHA_22980978_ChIP-Seq_HELA_Human2.10823669
27RNF2_27304074_Chip-Seq_ESCs_Mouse2.09932454
28IKZF1_21737484_ChIP-ChIP_HCT116_Human2.08759392
29AR_21572438_ChIP-Seq_LNCaP_Human1.99689574
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.96582325
31ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.94758387
32BMI1_23680149_ChIP-Seq_NPCS_Mouse1.88776974
33CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.87758314
34SMAD4_21799915_ChIP-Seq_A2780_Human1.77202752
35MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.75810983
36ZFP57_27257070_Chip-Seq_ESCs_Mouse1.73419609
37P300_19829295_ChIP-Seq_ESCs_Human1.71483496
38ERG_21242973_ChIP-ChIP_JURKAT_Human1.61074274
39ZNF274_21170338_ChIP-Seq_K562_Hela1.56541221
40PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.53242782
41HTT_18923047_ChIP-ChIP_STHdh_Human1.46276849
42* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.46120849
43ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.45558315
44PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.44390717
45FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.43394263
46NR3C1_23031785_ChIP-Seq_PC12_Mouse1.43006448
47SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.42549662
48SMAD3_21741376_ChIP-Seq_EPCs_Human1.41809907
49TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.41714955
50* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40616626
51GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.35987844
52PIAS1_25552417_ChIP-Seq_VCAP_Human1.34945826
53GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.33806258
54VDR_22108803_ChIP-Seq_LS180_Human1.32702558
55IGF1R_20145208_ChIP-Seq_DFB_Human1.32699420
56EWS_26573619_Chip-Seq_HEK293_Human1.32516826
57FUS_26573619_Chip-Seq_HEK293_Human1.30025145
58TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.29943639
59CBX2_27304074_Chip-Seq_ESCs_Mouse1.29000608
60SOX2_21211035_ChIP-Seq_LN229_Gbm1.28451052
61* AR_25329375_ChIP-Seq_VCAP_Human1.28080902
62EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.27638680
63POU3F2_20337985_ChIP-ChIP_501MEL_Human1.26899799
64SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.24964895
65BCAT_22108803_ChIP-Seq_LS180_Human1.23838004
66RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.23722153
67SRY_22984422_ChIP-ChIP_TESTIS_Rat1.22645048
68* CDX2_19796622_ChIP-Seq_MESCs_Mouse1.19670407
69OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18961221
70PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.16343845
71UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.16264671
72NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.16054527
73RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.16033823
74RNF2_27304074_Chip-Seq_NSC_Mouse1.13946933
75RING1B_27294783_Chip-Seq_ESCs_Mouse1.12369177
76STAT3_23295773_ChIP-Seq_U87_Human1.12199276
77CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.11272306
78RUNX2_22187159_ChIP-Seq_PCA_Human1.10162844
79DNAJC2_21179169_ChIP-ChIP_NT2_Human1.09505771
80RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.09365534
81P53_22127205_ChIP-Seq_FIBROBLAST_Human1.06462913
82PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.06224395
83TAL1_26923725_Chip-Seq_HPCs_Mouse1.06198560
84* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04473376
85* PRDM14_20953172_ChIP-Seq_ESCs_Human1.04343549
86NR3C1_21868756_ChIP-Seq_MCF10A_Human1.03682280
87AR_19668381_ChIP-Seq_PC3_Human1.02925224
88MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.02753607
89* TCF4_23295773_ChIP-Seq_U87_Human1.02500948
90* JUN_21703547_ChIP-Seq_K562_Human1.02264205
91CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.01522774
92AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.00350622
93BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.99353276
94ER_23166858_ChIP-Seq_MCF-7_Human0.99288947
95MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98860816
96FLI1_27457419_Chip-Seq_LIVER_Mouse0.96460504
97KLF5_20875108_ChIP-Seq_MESCs_Mouse0.96318817
98ARNT_22903824_ChIP-Seq_MCF-7_Human0.96204000
99EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.95299194
100* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.94122847
101* KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.94102152
102CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.93020872
103CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92887404
104NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.91968453
105NRF2_20460467_ChIP-Seq_MEFs_Mouse0.91968453
106SMAD4_21741376_ChIP-Seq_HESCs_Human0.91851240
107RING1B_27294783_Chip-Seq_NPCs_Mouse0.91559363
108SMAD_19615063_ChIP-ChIP_OVARY_Human0.89388432
109NANOG_18555785_Chip-Seq_ESCs_Mouse0.87802419
110* SMAD3_21741376_ChIP-Seq_ESCs_Human0.87676973
111AHR_22903824_ChIP-Seq_MCF-7_Human0.86798799
112RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.85931159
113MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.85607048
114YAP1_20516196_ChIP-Seq_MESCs_Mouse0.84538827
115ZNF217_24962896_ChIP-Seq_MCF-7_Human0.83185645
116* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.82469068
117SMAD4_21741376_ChIP-Seq_EPCs_Human0.82114966
118FLI1_21867929_ChIP-Seq_TH2_Mouse0.81860954
119FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.81735817
120TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.81269327
121KDM2B_26808549_Chip-Seq_REH_Human0.81215195
122* TP53_18474530_ChIP-ChIP_U2OS_Human0.80870053

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.15031935
2MP0003880_abnormal_central_pattern5.08066512
3MP0003635_abnormal_synaptic_transmissio3.87710452
4MP0002822_catalepsy3.57715773
5MP0009745_abnormal_behavioral_response3.47565072
6MP0009046_muscle_twitch3.39303320
7MP0001968_abnormal_touch/_nociception3.36525531
8MP0004270_analgesia3.32047303
9MP0002064_seizures3.27857594
10MP0002736_abnormal_nociception_after3.03132149
11MP0002063_abnormal_learning/memory/cond3.01859265
12MP0002572_abnormal_emotion/affect_behav2.77227057
13MP0002735_abnormal_chemical_nociception2.74868819
14MP0002272_abnormal_nervous_system2.70530605
15MP0001529_abnormal_vocalization2.70416637
16MP0002734_abnormal_mechanical_nocicepti2.66589694
17MP0001486_abnormal_startle_reflex2.57171686
18MP0001440_abnormal_grooming_behavior2.53037804
19MP0006276_abnormal_autonomic_nervous2.46856166
20MP0008875_abnormal_xenobiotic_pharmacok2.44170947
21MP0002733_abnormal_thermal_nociception2.39885815
22MP0001501_abnormal_sleep_pattern2.38004430
23MP0001970_abnormal_pain_threshold2.31903410
24MP0005423_abnormal_somatic_nervous2.14148216
25MP0002067_abnormal_sensory_capabilities2.12191018
26MP0004924_abnormal_behavior2.01715740
27MP0005386_behavior/neurological_phenoty2.01715740
28MP0002184_abnormal_innervation1.93201495
29MP0003011_delayed_dark_adaptation1.85490716
30MP0003879_abnormal_hair_cell1.85238876
31MP0008569_lethality_at_weaning1.77671492
32MP0001984_abnormal_olfaction1.77546776
33MP0001905_abnormal_dopamine_level1.71201397
34MP0002837_dystrophic_cardiac_calcinosis1.70305439
35MP0002557_abnormal_social/conspecific_i1.68301298
36MP0004811_abnormal_neuron_physiology1.57687923
37MP0004142_abnormal_muscle_tone1.54425978
38MP0000955_abnormal_spinal_cord1.51888371
39MP0000778_abnormal_nervous_system1.48730568
40MP0002909_abnormal_adrenal_gland1.48614474
41MP0003329_amyloid_beta_deposits1.48610083
42MP0000566_synostosis1.44205678
43MP0002066_abnormal_motor_capabilities/c1.41858217
44MP0004858_abnormal_nervous_system1.40388769
45MP0003122_maternal_imprinting1.38102275
46MP0006072_abnormal_retinal_apoptosis1.34477246
47MP0002882_abnormal_neuron_morphology1.32639024
48MP0005646_abnormal_pituitary_gland1.30003659
49MP0001502_abnormal_circadian_rhythm1.27172857
50MP0008872_abnormal_physiological_respon1.26517194
51MP0004043_abnormal_pH_regulation1.24597067
52MP0000751_myopathy1.21822586
53MP0001188_hyperpigmentation1.17205200
54MP0003137_abnormal_impulse_conducting1.16646761
55MP0008874_decreased_physiological_sensi1.12808530
56MP0004742_abnormal_vestibular_system1.11956666
57MP0003633_abnormal_nervous_system1.09191979
58MP0010386_abnormal_urinary_bladder1.07593217
59MP0002229_neurodegeneration1.07520473
60MP0008877_abnormal_DNA_methylation1.06825464
61MP0005535_abnormal_body_temperature1.06736522
62MP0009780_abnormal_chondrocyte_physiolo1.05719412
63MP0005410_abnormal_fertilization1.03884340
64MP0000358_abnormal_cell_content/1.02283772
65MP0000003_abnormal_adipose_tissue1.02091204
66MP0004084_abnormal_cardiac_muscle0.97521326
67MP0005551_abnormal_eye_electrophysiolog0.96364319
68MP0003631_nervous_system_phenotype0.95340327
69MP0004145_abnormal_muscle_electrophysio0.94512225
70MP0004147_increased_porphyrin_level0.92055664
71MP0001963_abnormal_hearing_physiology0.91990638
72MP0002152_abnormal_brain_morphology0.89454985
73MP0002277_abnormal_respiratory_mucosa0.88577653
74MP0004085_abnormal_heartbeat0.88304445
75MP0004885_abnormal_endolymph0.87028987
76MP0001485_abnormal_pinna_reflex0.84993722
77MP0002069_abnormal_eating/drinking_beha0.84018862
78MP0005171_absent_coat_pigmentation0.83853588
79MP0002752_abnormal_somatic_nervous0.83492665
80MP0002876_abnormal_thyroid_physiology0.82926692
81MP0005253_abnormal_eye_physiology0.81614220
82MP0000013_abnormal_adipose_tissue0.81145677
83MP0005409_darkened_coat_color0.80805970
84MP0002090_abnormal_vision0.80604205
85MP0003123_paternal_imprinting0.80072178
86MP0001664_abnormal_digestion0.79663711
87MP0003634_abnormal_glial_cell0.78595410
88MP0005645_abnormal_hypothalamus_physiol0.78501854
89MP0006035_abnormal_mitochondrial_morpho0.78226815
90MP0004215_abnormal_myocardial_fiber0.75126817
91MP0003787_abnormal_imprinting0.75114156
92MP0005499_abnormal_olfactory_system0.72714096
93MP0005394_taste/olfaction_phenotype0.72714096
94MP0009697_abnormal_copulation0.71741088
95MP0003183_abnormal_peptide_metabolism0.69615878
96MP0000920_abnormal_myelination0.68475234
97MP0004036_abnormal_muscle_relaxation0.67787046
98MP0008775_abnormal_heart_ventricle0.67206579
99MP0004484_altered_response_of0.67073962
100MP0000538_abnormal_urinary_bladder0.66125747
101MP0001986_abnormal_taste_sensitivity0.66106976
102MP0003632_abnormal_nervous_system0.65398376
103MP0003121_genomic_imprinting0.65286641
104MP0005595_abnormal_vascular_smooth0.64856389
105MP0001299_abnormal_eye_distance/0.64511437
106MP0002638_abnormal_pupillary_reflex0.63847619
107MP0000604_amyloidosis0.63697698
108MP0001348_abnormal_lacrimal_gland0.63202768
109MP0005623_abnormal_meninges_morphology0.62875305
110MP0003868_abnormal_feces_composition0.61587424
111MP0010329_abnormal_lipoprotein_level0.60610823
112MP0000631_abnormal_neuroendocrine_gland0.58279942
113MP0001765_abnormal_ion_homeostasis0.58214264
114MP0000534_abnormal_ureter_morphology0.57387509
115MP0000230_abnormal_systemic_arterial0.56721336
116MP0009379_abnormal_foot_pigmentation0.56482887
117MP0001756_abnormal_urination0.55531755
118MP0005620_abnormal_muscle_contractility0.54134864
119MP0001177_atelectasis0.53522733
120MP0003690_abnormal_glial_cell0.50874494
121MP0001943_abnormal_respiration0.50848227
122MP0000026_abnormal_inner_ear0.50175207
123MP0006036_abnormal_mitochondrial_physio0.49543002
124MP0005379_endocrine/exocrine_gland_phen0.49101404
125MP0005174_abnormal_tail_pigmentation0.48893947
126MP0003956_abnormal_body_size0.48660481
127MP0000569_abnormal_digit_pigmentation0.46154509
128MP0005220_abnormal_exocrine_pancreas0.45111938

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)8.57222504
2Focal motor seizures (HP:0011153)8.21670601
3Horizontal nystagmus (HP:0000666)5.93798524
4Focal seizures (HP:0007359)5.85722964
5Visual hallucinations (HP:0002367)5.56083572
6Atonic seizures (HP:0010819)5.43345607
7Intention tremor (HP:0002080)5.04630071
8Febrile seizures (HP:0002373)4.87421911
9Absence seizures (HP:0002121)4.59822946
10Epileptic encephalopathy (HP:0200134)4.32281185
11Dialeptic seizures (HP:0011146)4.13669670
12Generalized tonic-clonic seizures (HP:0002069)4.11686855
13Progressive cerebellar ataxia (HP:0002073)4.06229606
14Acute necrotizing encephalopathy (HP:0006965)3.91703479
15Abnormality of saccadic eye movements (HP:0000570)3.55742424
16Abnormal mitochondria in muscle tissue (HP:0008316)3.55187608
17Degeneration of the lateral corticospinal tracts (HP:0002314)3.52243808
18Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.52243808
19Abnormality of ocular smooth pursuit (HP:0000617)3.52113817
20Progressive macrocephaly (HP:0004481)3.48311985
21Mitochondrial inheritance (HP:0001427)3.36551168
22Action tremor (HP:0002345)3.35523840
23Pheochromocytoma (HP:0002666)3.25905328
24Broad-based gait (HP:0002136)3.17851840
25Acute encephalopathy (HP:0006846)3.16296655
26Hyperventilation (HP:0002883)3.14622487
27Limb ataxia (HP:0002070)3.08992536
28Gaze-evoked nystagmus (HP:0000640)3.06791200
29Anxiety (HP:0000739)3.04976644
30Neuroendocrine neoplasm (HP:0100634)3.03075199
31Abnormal hair whorl (HP:0010721)2.99209834
32Truncal ataxia (HP:0002078)2.88093025
33Amblyopia (HP:0000646)2.83943820
34Impaired vibration sensation in the lower limbs (HP:0002166)2.80017984
35Abnormal eating behavior (HP:0100738)2.78914089
36Dysdiadochokinesis (HP:0002075)2.78167273
37Limb dystonia (HP:0002451)2.75349678
38Increased hepatocellular lipid droplets (HP:0006565)2.73703632
39Increased CSF lactate (HP:0002490)2.70487310
40Resting tremor (HP:0002322)2.69640514
41Supranuclear gaze palsy (HP:0000605)2.69531657
42Dysmetria (HP:0001310)2.68861272
43Gait ataxia (HP:0002066)2.64682494
44Poor eye contact (HP:0000817)2.62283736
45Sensory axonal neuropathy (HP:0003390)2.62261942
46Depression (HP:0000716)2.58841602
47Scanning speech (HP:0002168)2.56730335
48Impaired vibratory sensation (HP:0002495)2.54861281
49Progressive inability to walk (HP:0002505)2.54115099
50Abnormal social behavior (HP:0012433)2.52886839
51Impaired social interactions (HP:0000735)2.52886839
52Focal dystonia (HP:0004373)2.51578383
53Myotonia (HP:0002486)2.49297563
54Hepatocellular necrosis (HP:0001404)2.47631223
55Ankle clonus (HP:0011448)2.46462394
56Torticollis (HP:0000473)2.46364028
57Optic disc pallor (HP:0000543)2.41069203
58Failure to thrive in infancy (HP:0001531)2.39257786
59Craniofacial dystonia (HP:0012179)2.33724257
60Renal Fanconi syndrome (HP:0001994)2.31999861
61Polyphagia (HP:0002591)2.27567557
62Annular pancreas (HP:0001734)2.25143810
63Lipid accumulation in hepatocytes (HP:0006561)2.24861942
64Urinary bladder sphincter dysfunction (HP:0002839)2.22177514
65Gait imbalance (HP:0002141)2.20558452
66Autoamputation (HP:0001218)2.18597867
67Spastic gait (HP:0002064)2.16772258
68Mutism (HP:0002300)2.16328640
69Drooling (HP:0002307)2.15716123
70Excessive salivation (HP:0003781)2.15716123
71Delusions (HP:0000746)2.15454501
72Hyperlipoproteinemia (HP:0010980)2.15416988
73Insidious onset (HP:0003587)2.15153076
74Termporal pattern (HP:0011008)2.15153076
75Bradykinesia (HP:0002067)2.14198433
76Cerebral inclusion bodies (HP:0100314)2.13969250
77Epileptiform EEG discharges (HP:0011182)2.13249458
78Urinary urgency (HP:0000012)2.13068852
79Fetal akinesia sequence (HP:0001989)2.12779216
80Abnormality of the anterior horn cell (HP:0006802)2.12314686
81Degeneration of anterior horn cells (HP:0002398)2.12314686
82Neoplasm of the peripheral nervous system (HP:0100007)2.12217765
83Hypoventilation (HP:0002791)2.11138713
84Status epilepticus (HP:0002133)2.09797562
85Psychosis (HP:0000709)2.08616734
86Leukodystrophy (HP:0002415)2.08569506
87EEG with generalized epileptiform discharges (HP:0011198)2.07724633
88Cerebellar atrophy (HP:0001272)2.07503652
89Increased intramyocellular lipid droplets (HP:0012240)2.07248433
90Poor suck (HP:0002033)2.02778046
91Postural instability (HP:0002172)2.02266875
92Impaired smooth pursuit (HP:0007772)2.00854210
93Incomplete penetrance (HP:0003829)1.99259360
94Inability to walk (HP:0002540)1.98774394
95X-linked dominant inheritance (HP:0001423)1.97042341
96Stereotypic behavior (HP:0000733)1.96969669
97Generalized myoclonic seizures (HP:0002123)1.96723895
98Hypothermia (HP:0002045)1.95793959
99Papilledema (HP:0001085)1.95656211
100Cerebral edema (HP:0002181)1.94435794
101Congenital primary aphakia (HP:0007707)1.93955061
102Hemiparesis (HP:0001269)1.93895983
103Hypsarrhythmia (HP:0002521)1.93241635
104Short chin (HP:0000331)1.92763648
105Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.91727238
106Increased serum pyruvate (HP:0003542)1.90875348
107Diplopia (HP:0000651)1.89843463
108Abnormality of binocular vision (HP:0011514)1.89843463
109Dysmetric saccades (HP:0000641)1.89476840
110Postural tremor (HP:0002174)1.85747086
111Agitation (HP:0000713)1.84296279
112Dysarthria (HP:0001260)1.83164226
113Slow progression (HP:0003677)1.82735709
114Medial flaring of the eyebrow (HP:0010747)1.81620235
115Abnormality of the corticospinal tract (HP:0002492)1.79870256
116Sudden death (HP:0001699)1.79707051
117Abnormality of the lower motor neuron (HP:0002366)1.76908350
118Esotropia (HP:0000565)1.74748119
119Epidermoid cyst (HP:0200040)1.69410232
120Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.63738937
121Athetosis (HP:0002305)1.62883269
122Abnormality of glycolysis (HP:0004366)1.60692345
123Choroideremia (HP:0001139)1.59149287
124Hemiplegia (HP:0002301)1.57215558
125Hepatic necrosis (HP:0002605)1.54569391
126Respiratory failure (HP:0002878)1.54491964
127Genital tract atresia (HP:0001827)1.50960572
128Exertional dyspnea (HP:0002875)1.49623464
129Syncope (HP:0001279)1.48215598
130Morphological abnormality of the pyramidal tract (HP:0002062)1.48011125
131Heterochromia iridis (HP:0001100)1.47867203
132Exercise intolerance (HP:0003546)1.46783747
133Vaginal atresia (HP:0000148)1.46308180
134Nephrogenic diabetes insipidus (HP:0009806)1.44851155
135Intellectual disability, mild (HP:0001256)1.44241634
136Decreased activity of mitochondrial respiratory chain (HP:0008972)1.43396632
137Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.43396632
138Aplasia involving bones of the upper limbs (HP:0009823)1.42271873
139Aplasia of the phalanges of the hand (HP:0009802)1.42271873
140Aplasia involving bones of the extremities (HP:0009825)1.42271873
141Abnormality of renal resorption (HP:0011038)1.41079112
142Increased muscle lipid content (HP:0009058)1.39364784

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.59065633
2MAP3K123.67347550
3EPHA43.59135132
4MAP3K93.38818586
5MAP3K43.34547607
6MAP2K72.94992657
7RIPK42.77421955
8MINK12.73790837
9CSNK1G32.66263490
10GRK52.54684993
11CSNK1A1L2.49377980
12MAP2K42.39078476
13CASK2.35241889
14PNCK2.32890939
15CSNK1G12.25637362
16ARAF2.19914515
17CDK192.09773295
18TTK1.94833365
19DAPK21.84275727
20MARK11.82588449
21CAMKK21.82077814
22KSR21.80916715
23PLK21.80682734
24PAK61.64840315
25CAMKK11.55866950
26TESK11.54021581
27PRKG21.50356567
28DAPK11.46795927
29PRKG11.45900800
30GRK71.41066436
31TNIK1.39455306
32NTRK21.34186899
33MAPK131.34061394
34PTK61.34035109
35CDK51.30894031
36NME11.28964606
37OXSR11.26405600
38NTRK11.26166504
39BMPR21.21032876
40KSR11.20664374
41FRK1.18742442
42MAP4K21.18179259
43PTK2B1.17679080
44PRKCG1.16193735
45FES1.09424002
46MAP3K21.06647197
47SIK21.06356393
48FGFR21.04627393
49SIK31.01861657
50LATS21.00901020
51TRIM281.00455639
52PAK41.00257558
53UHMK10.97831424
54CAMK2A0.97595504
55ADRBK10.96105983
56MUSK0.96043381
57MAP3K130.93552132
58FGR0.91174977
59CDK30.90564179
60CDK180.88425341
61RET0.87495473
62WNK10.85414774
63MYLK0.84526421
64CDK140.83512511
65CDK150.83062234
66PRKCA0.82906601
67STK380.82421066
68TNK20.81845355
69LMTK20.77075753
70TAF10.76264774
71PHKG20.74740510
72PHKG10.74740510
73CDK11A0.73006707
74PRPF4B0.72881288
75LIMK10.72438141
76CAMK2B0.72416828
77ADRBK20.72243064
78PRKD30.71368272
79MAP3K60.69912367
80SGK4940.68225100
81SGK2230.68225100
82CAMK10.67557297
83STK390.65771109
84BMPR1B0.65380400
85GRK60.64443742
86AKT30.64203668
87RAF10.63518692
88TYRO30.63448339
89CAMK2G0.61553596
90CSNK1G20.60821985
91PDK10.59869313
92PDPK10.59845106
93WNK30.59648225
94BRAF0.59140219
95CSNK1D0.58402895
96PRKDC0.57560960
97MAP2K10.57141259
98ILK0.57034486
99BCR0.56775363
100STK110.56501136
101DAPK30.56167759
102WNK40.54833460
103FER0.54658431
104MAP3K110.54623284
105DYRK1A0.54231134
106MAPKAPK50.53421672
107PRKCE0.52498389
108CAMK2D0.50321342
109ROCK20.49981393
110CSNK1E0.49361680
111PRKCH0.49266148
112GRK10.47902619
113SRC0.46956710
114PRKCB0.45518182
115PINK10.45329568
116PRKACA0.44038656
117SGK10.44003119
118TSSK60.43970388
119SGK20.43798047
120PAK30.43643485
121CAMK1G0.42887513
122MAP3K10.40082332
123SCYL20.38117429
124FYN0.34953333
125PRKACG0.34840774
126PRKCZ0.34566337
127MARK20.34375113
128MOS0.33166105
129RPS6KA30.32592322
130CSNK1A10.32093094
131CAMK40.32088977
132EIF2AK10.30837603
133STK160.29716390
134RPS6KB10.29413350
135INSRR0.26714416
136CHEK20.23439358
137PRKAA10.23034801
138MAPK10.22938102
139ITK0.20174375

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009104.95471923
2Oxidative phosphorylation_Homo sapiens_hsa001903.71004455
3Synaptic vesicle cycle_Homo sapiens_hsa047213.47988937
4Nicotine addiction_Homo sapiens_hsa050333.25692323
5Parkinsons disease_Homo sapiens_hsa050123.13138854
6Olfactory transduction_Homo sapiens_hsa047402.75445082
7Alzheimers disease_Homo sapiens_hsa050102.67589738
8Collecting duct acid secretion_Homo sapiens_hsa049662.54160726
9Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.50099372
10Long-term potentiation_Homo sapiens_hsa047202.43700006
11Cardiac muscle contraction_Homo sapiens_hsa042602.42697886
12GABAergic synapse_Homo sapiens_hsa047272.39229607
13Circadian entrainment_Homo sapiens_hsa047132.35393291
14Amphetamine addiction_Homo sapiens_hsa050312.33379117
15Morphine addiction_Homo sapiens_hsa050322.29825854
16Glutamatergic synapse_Homo sapiens_hsa047242.16905836
17Dopaminergic synapse_Homo sapiens_hsa047282.06582509
18Huntingtons disease_Homo sapiens_hsa050162.02150498
19Taste transduction_Homo sapiens_hsa047421.98678359
20Salivary secretion_Homo sapiens_hsa049701.98024302
21Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.88099742
22Cholinergic synapse_Homo sapiens_hsa047251.75200806
23Gastric acid secretion_Homo sapiens_hsa049711.72465140
24Renin secretion_Homo sapiens_hsa049241.69556493
25Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.69250598
26Long-term depression_Homo sapiens_hsa047301.68276374
27Serotonergic synapse_Homo sapiens_hsa047261.66012448
28Insulin secretion_Homo sapiens_hsa049111.59990592
29Aldosterone synthesis and secretion_Homo sapiens_hsa049251.57475043
30Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.52567164
31Cocaine addiction_Homo sapiens_hsa050301.51529481
32Calcium signaling pathway_Homo sapiens_hsa040201.49849803
33Pentose phosphate pathway_Homo sapiens_hsa000301.45334420
34Vibrio cholerae infection_Homo sapiens_hsa051101.45330964
35Oxytocin signaling pathway_Homo sapiens_hsa049211.44854253
36Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.39200891
37Fructose and mannose metabolism_Homo sapiens_hsa000511.37134470
38Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.32714014
39GnRH signaling pathway_Homo sapiens_hsa049121.30064885
40Phototransduction_Homo sapiens_hsa047441.24980763
41Protein export_Homo sapiens_hsa030601.23329879
42Gap junction_Homo sapiens_hsa045401.17016204
43Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.10639209
44Circadian rhythm_Homo sapiens_hsa047101.05785455
45Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.05331306
46Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.99975524
47Renin-angiotensin system_Homo sapiens_hsa046140.98130840
48cAMP signaling pathway_Homo sapiens_hsa040240.97272877
49Estrogen signaling pathway_Homo sapiens_hsa049150.94751504
50Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.90000156
51Phosphatidylinositol signaling system_Homo sapiens_hsa040700.89312804
52Glioma_Homo sapiens_hsa052140.88483660
53Melanogenesis_Homo sapiens_hsa049160.88140366
54Vascular smooth muscle contraction_Homo sapiens_hsa042700.87826216
55Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.87367777
56Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.78951297
57cGMP-PKG signaling pathway_Homo sapiens_hsa040220.77406017
58Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.74635401
59Oocyte meiosis_Homo sapiens_hsa041140.71685130
60Pyruvate metabolism_Homo sapiens_hsa006200.69731662
61Type II diabetes mellitus_Homo sapiens_hsa049300.68626004
62ErbB signaling pathway_Homo sapiens_hsa040120.68111276
63Pancreatic secretion_Homo sapiens_hsa049720.67097725
64Fatty acid elongation_Homo sapiens_hsa000620.65947775
65Axon guidance_Homo sapiens_hsa043600.64358280
66Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.59559077
67Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.59288799
68Thyroid hormone synthesis_Homo sapiens_hsa049180.59077412
69Glycerolipid metabolism_Homo sapiens_hsa005610.58886333
70Rheumatoid arthritis_Homo sapiens_hsa053230.58513344
71Dorso-ventral axis formation_Homo sapiens_hsa043200.58179172
72Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.55345553
73Mineral absorption_Homo sapiens_hsa049780.53469672
74Glycerophospholipid metabolism_Homo sapiens_hsa005640.52078961
75Glucagon signaling pathway_Homo sapiens_hsa049220.52018369
76Dilated cardiomyopathy_Homo sapiens_hsa054140.51745855
77Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.51273844
78Phospholipase D signaling pathway_Homo sapiens_hsa040720.50661588
79Regulation of autophagy_Homo sapiens_hsa041400.49868894
80Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.49577875
81VEGF signaling pathway_Homo sapiens_hsa043700.44513154
82Alcoholism_Homo sapiens_hsa050340.44180426
83Folate biosynthesis_Homo sapiens_hsa007900.43410448
84African trypanosomiasis_Homo sapiens_hsa051430.43056143
85MAPK signaling pathway_Homo sapiens_hsa040100.43042513
86Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.41694818
87Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.39498036
88Neurotrophin signaling pathway_Homo sapiens_hsa047220.38948260
89Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.38430895
90Carbon metabolism_Homo sapiens_hsa012000.37713785
91Inositol phosphate metabolism_Homo sapiens_hsa005620.37392735
92Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.36384057
93Ras signaling pathway_Homo sapiens_hsa040140.35519685
94Prion diseases_Homo sapiens_hsa050200.33207198
95Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.32566022
96Choline metabolism in cancer_Homo sapiens_hsa052310.32247411
97Sphingolipid signaling pathway_Homo sapiens_hsa040710.31918148
98Phagosome_Homo sapiens_hsa041450.30930176
99Rap1 signaling pathway_Homo sapiens_hsa040150.30304509
100Bile secretion_Homo sapiens_hsa049760.30068487
101Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.30035739
102Type I diabetes mellitus_Homo sapiens_hsa049400.29277834
103Sulfur metabolism_Homo sapiens_hsa009200.25964967
104Maturity onset diabetes of the young_Homo sapiens_hsa049500.25665536
105Insulin signaling pathway_Homo sapiens_hsa049100.23751571
106Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.23651495
107Non-small cell lung cancer_Homo sapiens_hsa052230.21410735
108SNARE interactions in vesicular transport_Homo sapiens_hsa041300.20773801
109Renal cell carcinoma_Homo sapiens_hsa052110.18535686
110Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.18186344
111Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.17954842
112Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.17752310
113Ovarian steroidogenesis_Homo sapiens_hsa049130.17510377
114Carbohydrate digestion and absorption_Homo sapiens_hsa049730.17143284
115Endocytosis_Homo sapiens_hsa041440.16935891
116Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.16927869
117Fatty acid biosynthesis_Homo sapiens_hsa000610.16372726
118Butanoate metabolism_Homo sapiens_hsa006500.16045256
119Biosynthesis of amino acids_Homo sapiens_hsa012300.15545607
120Wnt signaling pathway_Homo sapiens_hsa043100.13967795
121Metabolic pathways_Homo sapiens_hsa011000.13768970
122Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.12758925
123Fatty acid metabolism_Homo sapiens_hsa012120.12286049
124Retinol metabolism_Homo sapiens_hsa008300.11395964
125mTOR signaling pathway_Homo sapiens_hsa041500.09952841
126Sphingolipid metabolism_Homo sapiens_hsa006000.09614611
127Primary bile acid biosynthesis_Homo sapiens_hsa001200.07067591
128Propanoate metabolism_Homo sapiens_hsa006400.05234950

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