PCIF1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)6.96235480
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.69253855
3antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.69253855
4regulation of gamma-delta T cell differentiation (GO:0045586)5.68958243
5positive thymic T cell selection (GO:0045059)5.46171219
6regulation of gamma-delta T cell activation (GO:0046643)5.44733747
7antigen processing and presentation of endogenous antigen (GO:0019883)5.24449007
8positive T cell selection (GO:0043368)4.83651391
9antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.69879175
10negative regulation of erythrocyte differentiation (GO:0045647)4.60540094
11positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.58750849
12negative T cell selection (GO:0043383)4.36615299
13thymic T cell selection (GO:0045061)4.34485706
14negative thymic T cell selection (GO:0045060)4.21057458
15immunoglobulin mediated immune response (GO:0016064)4.19729136
16T cell selection (GO:0045058)4.17507334
17modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.16983016
18positive regulation by organism of defense response of other organism involved in symbiotic interact4.16983016
19modulation by symbiont of host immune response (GO:0052553)4.16983016
20positive regulation by symbiont of host defense response (GO:0052509)4.16983016
21modulation by symbiont of host defense response (GO:0052031)4.16983016
22modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.16983016
23negative regulation of mRNA splicing, via spliceosome (GO:0048025)4.06191369
24positive regulation of B cell differentiation (GO:0045579)4.03121614
25detection of bacterium (GO:0016045)4.01969237
26regulation of interleukin-12 biosynthetic process (GO:0045075)4.00316040
27negative regulation of RNA splicing (GO:0033119)3.93639623
28detection of other organism (GO:0098543)3.79864849
29positive regulation of histone deacetylation (GO:0031065)3.79036400
30megakaryocyte development (GO:0035855)3.74071463
31B cell receptor signaling pathway (GO:0050853)3.71878358
32response to muramyl dipeptide (GO:0032495)3.68656305
33regulation of B cell receptor signaling pathway (GO:0050855)3.66925890
34ribosomal small subunit assembly (GO:0000028)3.62133055
35negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.60843696
36negative regulation of cell killing (GO:0031342)3.60843696
37neutrophil activation involved in immune response (GO:0002283)3.60143434
38interferon-gamma production (GO:0032609)3.57280892
39regulation of B cell differentiation (GO:0045577)3.55793111
40negative regulation of phagocytosis (GO:0050765)3.55188483
41protein-DNA complex disassembly (GO:0032986)3.47762979
42nucleosome disassembly (GO:0006337)3.47762979
43regulation of dendritic cell antigen processing and presentation (GO:0002604)3.45878265
44antigen processing and presentation via MHC class Ib (GO:0002475)3.40362686
45natural killer cell differentiation (GO:0001779)3.39716911
46B cell mediated immunity (GO:0019724)3.37827384
47response to interleukin-15 (GO:0070672)3.37127042
48negative regulation of innate immune response (GO:0045824)3.29972869
49T cell receptor signaling pathway (GO:0050852)3.28926016
50T cell homeostasis (GO:0043029)3.28300516
51antigen receptor-mediated signaling pathway (GO:0050851)3.28048163
52regulation of erythrocyte differentiation (GO:0045646)3.27593187
53leukocyte aggregation (GO:0070486)3.27069255
54regulation of mast cell degranulation (GO:0043304)3.27045608
55response to host immune response (GO:0052572)3.24920700
56response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.24920700
57response to peptidoglycan (GO:0032494)3.24241646
58negative regulation of mRNA processing (GO:0050686)3.22912586
59T cell migration (GO:0072678)3.21994738
60NIK/NF-kappaB signaling (GO:0038061)3.21439844
61neutrophil activation (GO:0042119)3.15669587
62viral transcription (GO:0019083)3.15409009
63cellular response to zinc ion (GO:0071294)3.13289785
64negative regulation of lymphocyte mediated immunity (GO:0002707)3.10611006
65tolerance induction (GO:0002507)3.09344095
66positive regulation of gene expression, epigenetic (GO:0045815)3.06948302
67lymphocyte homeostasis (GO:0002260)3.06752996
68positive regulation of protein deacetylation (GO:0090312)3.06076847
69modulation by virus of host process (GO:0019054)3.02333570
703-UTR-mediated mRNA stabilization (GO:0070935)3.02086766
71negative regulation of leukocyte mediated immunity (GO:0002704)3.00569543
72regulation of myeloid leukocyte mediated immunity (GO:0002886)2.99244001
73JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.97872352
74Peyers patch development (GO:0048541)2.96342070
75mucosal-associated lymphoid tissue development (GO:0048537)2.96342070
76response to host (GO:0075136)2.95471395
77response to host defenses (GO:0052200)2.95471395
78response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.95471395
79negative regulation of mRNA metabolic process (GO:1903312)2.92446889
80positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.92014479
81granulocyte activation (GO:0036230)2.91939576
82regulation of interferon-beta biosynthetic process (GO:0045357)2.90579501
83positive regulation of transcription regulatory region DNA binding (GO:2000679)2.88540745
84regulation of mast cell activation involved in immune response (GO:0033006)2.88196210
85embryonic hemopoiesis (GO:0035162)2.88195040
86T cell costimulation (GO:0031295)2.88054318
87regulation of leukocyte degranulation (GO:0043300)2.88042645
88negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.86703753
89dosage compensation (GO:0007549)2.85699904
90positive regulation of antigen processing and presentation (GO:0002579)2.85641245
91positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.84726148
92regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.84410208
93response to interferon-beta (GO:0035456)2.83027212
94translational termination (GO:0006415)2.82376475
95respiratory burst (GO:0045730)2.81782550
96cellular response to virus (GO:0098586)2.81748911
97lymphocyte costimulation (GO:0031294)2.81512535
98DNA unwinding involved in DNA replication (GO:0006268)2.81022337
99regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.79308856
100negative regulation of glycoprotein biosynthetic process (GO:0010561)2.78420523
101negative regulation of granulocyte differentiation (GO:0030853)2.78143896
102regulation of antigen processing and presentation (GO:0002577)2.77329380
103hepatocyte apoptotic process (GO:0097284)2.77301425
104negative regulation of T cell mediated immunity (GO:0002710)2.76194973
105macrophage activation involved in immune response (GO:0002281)2.74568058
106positive regulation of granulocyte differentiation (GO:0030854)2.74216697
107regulation of T cell mediated cytotoxicity (GO:0001914)2.73759536
108negative regulation of B cell apoptotic process (GO:0002903)2.73250118
109positive regulation of erythrocyte differentiation (GO:0045648)2.72750371
110leukocyte homeostasis (GO:0001776)2.72444337
111regulation of granulocyte differentiation (GO:0030852)2.71980889
112actin nucleation (GO:0045010)2.71257730
113translational elongation (GO:0006414)2.70511684
114regulation of T cell tolerance induction (GO:0002664)2.69639411
115erythrocyte maturation (GO:0043249)2.67777834
116regulation of alpha-beta T cell proliferation (GO:0046640)2.67508925
117mast cell activation (GO:0045576)2.66382586
118myeloid cell activation involved in immune response (GO:0002275)2.65541842
119positive regulation of T cell mediated cytotoxicity (GO:0001916)2.64804686
120regulation of protein heterodimerization activity (GO:0043497)2.64743539
121response to type I interferon (GO:0034340)2.63488039
122deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.62243207
123leukocyte degranulation (GO:0043299)2.61106679
124detection of external biotic stimulus (GO:0098581)2.60395252
125positive regulation of natural killer cell differentiation (GO:0032825)2.60076737
126germinal center formation (GO:0002467)2.59998930
127cellular response to interleukin-15 (GO:0071350)2.59562831
128regulation of type I interferon-mediated signaling pathway (GO:0060338)2.58814033
129negative regulation of interleukin-12 production (GO:0032695)2.58527112
130interferon-gamma-mediated signaling pathway (GO:0060333)2.58198375
131cellular response to interleukin-4 (GO:0071353)2.58156752
132platelet formation (GO:0030220)2.54044458
133positive regulation of RNA splicing (GO:0033120)2.53892490
134intracellular estrogen receptor signaling pathway (GO:0030520)2.53734061
135regulation of mast cell activation (GO:0033003)2.53704677
136histone H2A acetylation (GO:0043968)2.53374017
137natural killer cell activation (GO:0030101)2.53129169
138definitive hemopoiesis (GO:0060216)2.51862289
139pre-miRNA processing (GO:0031054)2.51189395
140cellular response to type I interferon (GO:0071357)2.51149303
141type I interferon signaling pathway (GO:0060337)2.51149303
142positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.49505813
143regulation of T cell receptor signaling pathway (GO:0050856)2.48280428
144negative regulation of gene expression, epigenetic (GO:0045814)2.47994389
145negative regulation of histone methylation (GO:0031061)2.47049368
146response to pheromone (GO:0019236)2.45657939
147immune response-activating cell surface receptor signaling pathway (GO:0002429)2.44656351
148regulation of defense response to virus by virus (GO:0050690)2.43108407
149angiogenesis involved in wound healing (GO:0060055)2.42647827
150Arp2/3 complex-mediated actin nucleation (GO:0034314)2.42158324
151positive regulation by host of viral transcription (GO:0043923)2.41691080
152adaptation of signaling pathway (GO:0023058)2.40754869
153mRNA stabilization (GO:0048255)2.40130241
154RNA stabilization (GO:0043489)2.40130241

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.46808333
2MYC_22102868_ChIP-Seq_BL_Human4.38329500
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.51750274
4VDR_21846776_ChIP-Seq_THP-1_Human3.38533576
5BP1_19119308_ChIP-ChIP_Hs578T_Human3.16087230
6SCL_19346495_ChIP-Seq_HPC-7_Human3.05292068
7* TCF7_22412390_ChIP-Seq_EML_Mouse2.69532915
8* CIITA_25753668_ChIP-Seq_RAJI_Human2.68163989
9FOXM1_23109430_ChIP-Seq_U2OS_Human2.66249253
10FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.63929370
11EGR1_19374776_ChIP-ChIP_THP-1_Human2.62532738
12MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.57004823
13UTX_26944678_Chip-Seq_JUKART_Human2.55860208
14MAF_26560356_Chip-Seq_TH1_Human2.51896771
15EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.37446289
16KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.36061595
17KDM2B_26808549_Chip-Seq_DND41_Human2.33287383
18SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.32293736
19RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.25994658
20KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.24970692
21IRF8_22096565_ChIP-ChIP_GC-B_Human2.24527375
22KDM2B_26808549_Chip-Seq_SUP-B15_Human2.19144483
23IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.12786970
24VDR_24763502_ChIP-Seq_THP-1_Human2.12639413
25E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.10585199
26* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.09963684
27TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.07332024
28IRF8_21731497_ChIP-ChIP_J774_Mouse2.04611910
29NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.03306245
30* MYB_26560356_Chip-Seq_TH2_Human2.00522369
31* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.97042407
32SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.95498086
33* MYB_26560356_Chip-Seq_TH1_Human1.91167653
34RUNX_20019798_ChIP-Seq_JUKART_Human1.89394662
35MAF_26560356_Chip-Seq_TH2_Human1.85004319
36ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.81348530
37RUNX1_22412390_ChIP-Seq_EML_Mouse1.80388611
38* ELK3_25401928_ChIP-Seq_HUVEC_Human1.80051525
39STAT4_19710469_ChIP-ChIP_TH1__Mouse1.79832404
40SPI1_23127762_ChIP-Seq_K562_Human1.77047769
41* LXR_22292898_ChIP-Seq_THP-1_Human1.76857111
42TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.74569906
43STAT6_21828071_ChIP-Seq_BEAS2B_Human1.67568909
44BRD4_27068464_Chip-Seq_AML-cells_Mouse1.63770031
45GATA1_19941827_ChIP-Seq_MEL_Mouse1.61769755
46MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.61629518
47GATA1_22383799_ChIP-Seq_G1ME_Mouse1.61581486
48KDM2B_26808549_Chip-Seq_JURKAT_Human1.60295198
49* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.58430434
50CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.55778113
51TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.55271165
52SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.54488404
53NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.53618896
54SPI1_23547873_ChIP-Seq_NB4_Human1.53216246
55DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.49213864
56E2F4_17652178_ChIP-ChIP_JURKAT_Human1.42082244
57* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.41284236
58SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.36953279
59ELF1_17652178_ChIP-ChIP_JURKAT_Human1.36639295
60VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.33654197
61* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.33091133
62NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.32858691
63PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.32849489
64STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.32685423
65NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.32590690
66CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.30020234
67MYB_21317192_ChIP-Seq_ERMYB_Mouse1.28711268
68SRY_22984422_ChIP-ChIP_TESTIS_Rat1.28574214
69PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.27990074
70THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.26992513
71HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.26387567
72TET1_21451524_ChIP-Seq_MESCs_Mouse1.25925991
73P68_20966046_ChIP-Seq_HELA_Human1.25465347
74* NCOR1_26117541_ChIP-Seq_K562_Human1.25214501
75GATA1_19941826_ChIP-Seq_K562_Human1.24668598
76GATA2_22383799_ChIP-Seq_G1ME_Mouse1.24637387
77LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.24223573
78* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.23372585
79CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.23099751
80* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.21226674
81EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.20086239
82XRN2_22483619_ChIP-Seq_HELA_Human1.19340028
83CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.18592963
84CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.15855174
85BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.15791608
86CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.14614916
87CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.14606221
88GATA3_27048872_Chip-Seq_THYMUS_Human1.12689097
89BCL6_27268052_Chip-Seq_Bcells_Human1.12297681
90PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.11750320
91RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.11499687
92GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.10654401
93CTCF_27219007_Chip-Seq_ERYTHROID_Human1.09863358
94LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.08870967
95PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.08555941
96ETS1_21867929_ChIP-Seq_TH2_Mouse1.07899871
97* IRF8_27001747_Chip-Seq_BMDM_Mouse1.07860903
98SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.07794898
99CTCF_26484167_Chip-Seq_Bcells_Mouse1.07656251
100ELF1_20517297_ChIP-Seq_JURKAT_Human1.07639160
101IKZF1_21737484_ChIP-ChIP_HCT116_Human1.05448367
102RACK7_27058665_Chip-Seq_MCF-7_Human1.05323176
103BCOR_27268052_Chip-Seq_Bcells_Human1.04861282
104SA1_27219007_Chip-Seq_ERYTHROID_Human1.03566943
105IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.02629333
106DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.01922195
107KDM5A_27292631_Chip-Seq_BREAST_Human1.01047252
108E2F1_21310950_ChIP-Seq_MCF-7_Human1.01010199
109CTCF_21964334_ChIP-Seq_BJAB-B_Human1.00826565
110* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.99847217
111* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.99821708
112FOXP3_21729870_ChIP-Seq_TREG_Human0.99223174
113* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.98050594
114KDM2B_26808549_Chip-Seq_K562_Human0.97541516
115SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.96272921
116KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.95312908
117GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94643009
118FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.94474002
119PU.1_20513432_ChIP-Seq_Bcells_Mouse0.93785584
120DNAJC2_21179169_ChIP-ChIP_NT2_Human0.92866404
121STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.86811321
122CTCF_21964334_Chip-Seq_Bcells_Human0.86606408
123GATA1_22025678_ChIP-Seq_K562_Human0.86176358

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology3.80187682
2MP0002396_abnormal_hematopoietic_system3.22826865
3MP0003300_gastrointestinal_ulcer3.19845185
4MP0000685_abnormal_immune_system3.12185112
5MP0005671_abnormal_response_to2.72025198
6MP0002398_abnormal_bone_marrow2.68081978
7MP0005387_immune_system_phenotype2.66993877
8MP0001790_abnormal_immune_system2.66993877
9MP0001800_abnormal_humoral_immune2.66415072
10MP0001835_abnormal_antigen_presentation2.63738349
11MP0009278_abnormal_bone_marrow2.62238303
12MP0000703_abnormal_thymus_morphology2.47963212
13MP0008260_abnormal_autophagy2.45296321
14MP0003303_peritoneal_inflammation2.31433147
15MP0005174_abnormal_tail_pigmentation2.30968868
16MP0000465_gastrointestinal_hemorrhage2.27047518
17MP0002420_abnormal_adaptive_immunity2.23744318
18MP0004808_abnormal_hematopoietic_stem2.20055314
19MP0001819_abnormal_immune_cell2.19797789
20MP0005058_abnormal_lysosome_morphology2.18344363
21MP0002722_abnormal_immune_system2.18222455
22MP0000716_abnormal_immune_system2.14584592
23MP0002452_abnormal_antigen_presenting2.12316119
24MP0003866_abnormal_defecation2.10996471
25MP0005397_hematopoietic_system_phenotyp2.10168626
26MP0001545_abnormal_hematopoietic_system2.10168626
27MP0000689_abnormal_spleen_morphology2.09742462
28MP0002723_abnormal_immune_serum2.06896818
29MP0002166_altered_tumor_susceptibility2.05315289
30MP0005000_abnormal_immune_tolerance1.99631431
31MP0003172_abnormal_lysosome_physiology1.99002546
32MP0001873_stomach_inflammation1.97263901
33MP0008961_abnormal_basal_metabolism1.95389271
34MP0009333_abnormal_splenocyte_physiolog1.93435976
35MP0002405_respiratory_system_inflammati1.91607645
36MP0002429_abnormal_blood_cell1.90441085
37MP0005464_abnormal_platelet_physiology1.86426005
38MP0005025_abnormal_response_to1.77610906
39MP0003436_decreased_susceptibility_to1.75412327
40MP0010155_abnormal_intestine_physiology1.73889938
41MP0002877_abnormal_melanocyte_morpholog1.71778173
42MP0000490_abnormal_crypts_of1.68528917
43MP0006054_spinal_hemorrhage1.58422158
44MP0002653_abnormal_ependyma_morphology1.51449934
45MP0003111_abnormal_nucleus_morphology1.48091438
46MP0004947_skin_inflammation1.47921887
47MP0005451_abnormal_body_composition1.44584076
48MP0005409_darkened_coat_color1.43389581
49MP0009785_altered_susceptibility_to1.38567903
50MP0008007_abnormal_cellular_replicative1.36317772
51MP0005076_abnormal_cell_differentiation1.33999527
52MP0004510_myositis1.30183095
53MP0002419_abnormal_innate_immunity1.27195732
54MP0003656_abnormal_erythrocyte_physiolo1.26284932
55MP0006082_CNS_inflammation1.26002792
56MP0008469_abnormal_protein_level1.25890762
57MP0003077_abnormal_cell_cycle1.24599989
58MP0004381_abnormal_hair_follicle1.23661473
59MP0002095_abnormal_skin_pigmentation1.23566299
60MP0002006_tumorigenesis1.23044273
61MP0001845_abnormal_inflammatory_respons1.21166317
62MP0002019_abnormal_tumor_incidence1.19841767
63MP0000569_abnormal_digit_pigmentation1.19319583
64MP0003828_pulmonary_edema1.19206220
65MP0003075_altered_response_to1.19127539
66MP0000015_abnormal_ear_pigmentation1.18896154
67MP0002089_abnormal_postnatal_growth/wei1.17512957
68MP0005310_abnormal_salivary_gland1.17098467
69MP0002148_abnormal_hypersensitivity_rea1.14952879
70MP0000566_synostosis1.13352091
71MP0009840_abnormal_foam_cell1.10802123
72MP0000678_abnormal_parathyroid_gland1.08737109
73MP0009764_decreased_sensitivity_to1.05024465
74MP0002009_preneoplasia1.00518655
75MP0005075_abnormal_melanosome_morpholog0.97772954
76MP0010094_abnormal_chromosome_stability0.96447613
77MP0008569_lethality_at_weaning0.94292341
78MP0005083_abnormal_biliary_tract0.94122850
79MP0001851_eye_inflammation0.93196294
80MP0004147_increased_porphyrin_level0.92158852
81MP0009763_increased_sensitivity_to0.90739793
82MP0002928_abnormal_bile_duct0.90270126
83MP0009379_abnormal_foot_pigmentation0.90258277
84MP0002132_abnormal_respiratory_system0.90217900
85MP0003693_abnormal_embryo_hatching0.89754836
86MP0002933_joint_inflammation0.89045264
87MP0006036_abnormal_mitochondrial_physio0.88760609
88MP0005390_skeleton_phenotype0.86941258
89MP0000313_abnormal_cell_death0.85667855
90MP0002998_abnormal_bone_remodeling0.84540413
91MP0008995_early_reproductive_senescence0.78950541
92MP0004185_abnormal_adipocyte_glucose0.78684142
93MP0008874_decreased_physiological_sensi0.78596412
94MP0001849_ear_inflammation0.77002478
95MP0002138_abnormal_hepatobiliary_system0.76645868
96MP0000477_abnormal_intestine_morphology0.76105658
97MP0010352_gastrointestinal_tract_polyps0.75765011
98MP0003943_abnormal_hepatobiliary_system0.74699637
99MP0002693_abnormal_pancreas_physiology0.74640967
100MP0000858_altered_metastatic_potential0.72252564
101MP0001944_abnormal_pancreas_morphology0.71728643
102MP0002332_abnormal_exercise_endurance0.71583691
103MP0008058_abnormal_DNA_repair0.71290441
104MP0003787_abnormal_imprinting0.70831057
105MP0005166_decreased_susceptibility_to0.70628247
106MP0000350_abnormal_cell_proliferation0.70262324
107MP0000343_altered_response_to0.68071630
108MP0003795_abnormal_bone_structure0.67925405
109MP0005670_abnormal_white_adipose0.67321683
110MP0009765_abnormal_xenobiotic_induced0.67184581
111MP0003183_abnormal_peptide_metabolism0.66827777
112MP0001270_distended_abdomen0.66725558
113MP0003806_abnormal_nucleotide_metabolis0.66329503
114MP0003329_amyloid_beta_deposits0.65099904
115MP0001663_abnormal_digestive_system0.64363051
116MP0005666_abnormal_adipose_tissue0.63545926
117MP0003724_increased_susceptibility_to0.63469065
118MP0003191_abnormal_cellular_cholesterol0.62508498
119MP0001879_abnormal_lymphatic_vessel0.62199979
120MP0001533_abnormal_skeleton_physiology0.61585782
121MP0009672_abnormal_birth_weight0.61179615
122MP0005375_adipose_tissue_phenotype0.60767232
123MP0000604_amyloidosis0.59308701
124MP0005535_abnormal_body_temperature0.59026982
125MP0004957_abnormal_blastocyst_morpholog0.58473847
126MP0001853_heart_inflammation0.57434216
127MP0005220_abnormal_exocrine_pancreas0.57365945
128MP0008004_abnormal_stomach_pH0.56925744
129MP0001730_embryonic_growth_arrest0.56900685
130MP0000751_myopathy0.55530436
131MP0008873_increased_physiological_sensi0.54611029
132MP0005319_abnormal_enzyme/_coenzyme0.53790200
133MP0003221_abnormal_cardiomyocyte_apopto0.53742817
134MP0000681_abnormal_thyroid_gland0.52372619
135MP0002277_abnormal_respiratory_mucosa0.51308849
136MP0005621_abnormal_cell_physiology0.50638316
137MP0001986_abnormal_taste_sensitivity0.49773692
138MP0002083_premature_death0.49546463
139MP0003448_altered_tumor_morphology0.48286074

Predicted human phenotypes

RankGene SetZ-score
1Abnormal delayed hypersensitivity skin test (HP:0002963)4.91111480
2Abnormality of the fingertips (HP:0001211)4.51084069
3Panhypogammaglobulinemia (HP:0003139)4.44148375
4Stomatitis (HP:0010280)4.20856107
5Hyperacusis (HP:0010780)3.87609311
6Abnormality of macrophages (HP:0004311)3.78321658
7IgM deficiency (HP:0002850)3.68414392
8Recurrent viral infections (HP:0004429)3.67091468
9Chronic otitis media (HP:0000389)3.66153199
10Chronic obstructive pulmonary disease (HP:0006510)3.64094250
11Obstructive lung disease (HP:0006536)3.64094250
12Agammaglobulinemia (HP:0004432)3.60141311
13Gastrointestinal inflammation (HP:0004386)3.50627166
14Inflammation of the large intestine (HP:0002037)3.46165193
15Cellulitis (HP:0100658)3.38575417
16Colitis (HP:0002583)3.36608286
17Recurrent fungal infections (HP:0002841)3.34629599
18Recurrent bronchitis (HP:0002837)3.33866907
19Papilloma (HP:0012740)3.23457146
20Verrucae (HP:0200043)3.23457146
21Abnormality of the heme biosynthetic pathway (HP:0010472)3.22324645
22Purpura (HP:0000979)3.17606972
23Increased IgM level (HP:0003496)3.16797928
24Abnormality of the nasal mucosa (HP:0000433)3.15836044
25Abnormality of T cells (HP:0002843)3.06771501
26Elevated erythrocyte sedimentation rate (HP:0003565)3.05014667
27T lymphocytopenia (HP:0005403)3.04452781
28Spontaneous hematomas (HP:0007420)3.01349335
29Increased cerebral lipofuscin (HP:0011813)2.98901195
30Nasal polyposis (HP:0100582)2.93687053
31Meningitis (HP:0001287)2.92849512
32Myositis (HP:0100614)2.92469359
33Increased neuronal autofluorescent lipopigment (HP:0002074)2.89374122
34Abnormality of T cell physiology (HP:0011840)2.83470556
35Chronic mucocutaneous candidiasis (HP:0002728)2.81575921
36Recurrent cutaneous fungal infections (HP:0011370)2.81575921
37Abnormality of T cell number (HP:0011839)2.79243523
38Pustule (HP:0200039)2.76287864
39Loss of speech (HP:0002371)2.70878045
40Insomnia (HP:0100785)2.70865299
41Lymphopenia (HP:0001888)2.70725714
42Abnormality of cells of the lymphoid lineage (HP:0012140)2.69688422
43Thrombocytosis (HP:0001894)2.67583679
44Urticaria (HP:0001025)2.64724043
45Growth hormone excess (HP:0000845)2.60382919
46Hypergammaglobulinemia (HP:0010702)2.58217267
47Polygenic inheritance (HP:0010982)2.52948322
48Eczematoid dermatitis (HP:0000976)2.52470974
49Peripheral hypomyelination (HP:0007182)2.51133297
50Dysostosis multiplex (HP:0000943)2.46879417
51Abnormality of B cell number (HP:0010975)2.46044129
52B lymphocytopenia (HP:0010976)2.46044129
53Gastrointestinal infarctions (HP:0005244)2.43232144
54Recurrent gram-negative bacterial infections (HP:0005420)2.42413487
55Hepatosplenomegaly (HP:0001433)2.42239390
56Prolonged bleeding time (HP:0003010)2.40590987
57Increased IgE level (HP:0003212)2.40120992
58Sepsis (HP:0100806)2.39552344
59Centrally nucleated skeletal muscle fibers (HP:0003687)2.36447686
60Interstitial pulmonary disease (HP:0006530)2.36210284
61Cholecystitis (HP:0001082)2.35425263
62Abnormal gallbladder physiology (HP:0012438)2.35425263
63Elfin facies (HP:0004428)2.34012179
64Abnormality of glycolipid metabolism (HP:0010969)2.31751742
65Abnormality of liposaccharide metabolism (HP:0010968)2.31751742
66Abnormality of glycosphingolipid metabolism (HP:0004343)2.31751742
67Thyroiditis (HP:0100646)2.31518623
68Gingival bleeding (HP:0000225)2.31093965
69Acute lymphatic leukemia (HP:0006721)2.28997843
70Gastrointestinal stroma tumor (HP:0100723)2.27254996
71Severe combined immunodeficiency (HP:0004430)2.27024280
72Progressive neurologic deterioration (HP:0002344)2.24385237
73Long eyelashes (HP:0000527)2.24282210
74Episodic fever (HP:0001954)2.23839153
75Visual hallucinations (HP:0002367)2.23826713
76Chest pain (HP:0100749)2.23271748
77Recurrent abscess formation (HP:0002722)2.22483914
78Periodontitis (HP:0000704)2.20176737
79Pulmonary infiltrates (HP:0002113)2.19928560
80Stomach cancer (HP:0012126)2.18618800
81Long palpebral fissure (HP:0000637)2.17378106
82Petechiae (HP:0000967)2.17345047
83Short 4th metacarpal (HP:0010044)2.16819234
84Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.16819234
85Ragged-red muscle fibers (HP:0003200)2.16757201
86Combined immunodeficiency (HP:0005387)2.15970375
87Hypochromic microcytic anemia (HP:0004840)2.15288631
88Hypertensive crisis (HP:0100735)2.15157841
89Autoimmune hemolytic anemia (HP:0001890)2.12601553
90Keratoconjunctivitis sicca (HP:0001097)2.09049425
91Viral hepatitis (HP:0006562)2.07905239
92Overriding aorta (HP:0002623)2.07867124
93Basal cell carcinoma (HP:0002671)2.06381256
94Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.05624922
95Increased serum ferritin (HP:0003281)2.05619190
96IgG deficiency (HP:0004315)2.04805796
97Ankle clonus (HP:0011448)2.04191447
98Gingivitis (HP:0000230)2.02635243
99Bronchitis (HP:0012387)2.00668180
100Abnormality of iron homeostasis (HP:0011031)1.99592402
101Increased nuchal translucency (HP:0010880)1.99344067
102Hematochezia (HP:0002573)1.99120146
103Abnormality of the prostate (HP:0008775)1.98937735
104Hypochromic anemia (HP:0001931)1.98331646
105Fatigue (HP:0012378)1.98299945
106Volvulus (HP:0002580)1.97432168
107Acute hepatic failure (HP:0006554)1.96645080
108Renovascular hypertension (HP:0100817)1.95961763
109Bicuspid aortic valve (HP:0001647)1.94307486
110Hemoptysis (HP:0002105)1.94126174
111Myopathic facies (HP:0002058)1.93953245
112Pointed chin (HP:0000307)1.92921744
113Slow saccadic eye movements (HP:0000514)1.92816414
114Autoimmune thrombocytopenia (HP:0001973)1.92458474
115Orchitis (HP:0100796)1.92092110
116Abnormality of the pleura (HP:0002103)1.91929430
117Eosinophilia (HP:0001880)1.91571556
118Reticulocytopenia (HP:0001896)1.91326707
119Osteomyelitis (HP:0002754)1.90800445
120Chronic sinusitis (HP:0011109)1.90557561
121Keratoconjunctivitis (HP:0001096)1.89305608
122Encephalitis (HP:0002383)1.89038810
123Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.88804739
124Joint swelling (HP:0001386)1.88399557
125Seborrheic dermatitis (HP:0001051)1.88018057
126Recurrent sinusitis (HP:0011108)1.87859933
127Thin bony cortex (HP:0002753)1.86410782
128Recurrent skin infections (HP:0001581)1.85573277
129Epistaxis (HP:0000421)1.85393478
130Increased density of long bones (HP:0006392)1.84580423
131Lymphoma (HP:0002665)1.84292661
132Obsessive-compulsive behavior (HP:0000722)1.83549277
133Cerebral aneurysm (HP:0004944)1.83230600
134Mediastinal lymphadenopathy (HP:0100721)1.82757189
135Recurrent bacterial skin infections (HP:0005406)1.82720016
136Absent rod-and cone-mediated responses on ERG (HP:0007688)1.82328875
137Leukocytosis (HP:0001974)1.79718108
138Emphysema (HP:0002097)1.78932598
139Microcytic anemia (HP:0001935)1.78729363
140Abnormality of the endocardium (HP:0004306)1.78649687
141Renal duplication (HP:0000075)1.77866319
142Arterial thrombosis (HP:0004420)1.76466041
143Prominent nose (HP:0000448)1.75810838
144Abnormality of eosinophils (HP:0001879)1.75265469
145Retrobulbar optic neuritis (HP:0100654)1.72980196
146Optic neuritis (HP:0100653)1.72980196
147Vasculitis (HP:0002633)1.72764613
148Granulocytopenia (HP:0001913)1.70923245
149Limb hypertonia (HP:0002509)1.69081399
150Deep palmar crease (HP:0006191)1.68407558
151Optic nerve coloboma (HP:0000588)1.67113829
152Flat cornea (HP:0007720)1.67083165

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.54456428
2MAP3K103.88140993
3EEF2K3.62172570
4TRIB33.44242975
5PRPF4B3.00169709
6RIPK42.75525935
7PKN22.63395894
8SIK32.41566544
9ERN12.17443458
10BTK1.95307837
11ZAP701.92633468
12GRK61.82531407
13TESK11.76957795
14TXK1.72770772
15NEK21.72684019
16JAK31.72044114
17MAP4K21.70327590
18TAOK21.69872303
19STK101.67926682
20LRRK21.62444013
21TYK21.61010484
22TGFBR21.56203478
23PTK61.51574618
24TAOK31.48293388
25CLK11.47863486
26HIPK21.46576523
27ITK1.46209137
28CSF1R1.44079396
29IKBKE1.41094634
30TLK11.38816638
31KIT1.36504967
32FGFR41.36399833
33SIK21.33521654
34MAP2K21.32447282
35IRAK21.31836205
36BLK1.30969464
37SYK1.27010375
38MAP3K31.26928903
39RIPK11.24779417
40BCKDK1.21234088
41TBK11.18280330
42FLT31.17235660
43PASK1.14131963
44TGFBR11.13330866
45CDK121.10801532
46BRD41.08644878
47MARK21.06298163
48NME21.06184369
49EPHB11.05362983
50DMPK1.05296093
51VRK21.04406509
52MAP2K31.03261210
53PRKCH1.02253805
54JAK11.02172155
55RPS6KA41.00485988
56PIM21.00333577
57SGK30.98933209
58ALK0.98761104
59HCK0.95953234
60LCK0.92648823
61MAP3K10.91810022
62STK40.91612758
63SMG10.90816175
64PIM10.90815021
65SIK10.89990470
66EPHA30.89644954
67KDR0.88759919
68PRKD20.88667814
69SRPK10.88026598
70IRAK40.86851522
71NLK0.84464460
72FGR0.84283235
73FES0.83794129
74MAP3K70.82864913
75MARK30.82748964
76CDK40.80896055
77FGFR30.79829749
78DAPK10.78037857
79LMTK20.77642122
80JAK20.76761841
81TTN0.76408101
82CSK0.75522684
83TEC0.75342335
84TAOK10.72952307
85CHUK0.72825181
86RPS6KB20.71265916
87SCYL20.70370980
88CDC70.69336460
89TESK20.68498847
90MATK0.68362828
91IRAK10.68090606
92PRKD30.67498951
93TNK20.65796739
94MAP3K50.64021273
95ARAF0.63994049
96DYRK1B0.63085358
97NTRK20.62176650
98MAPK120.60300797
99IKBKB0.60155953
100RPS6KA60.58999277
101CAMK40.58866062
102YES10.57240398
103MAPKAPK20.57091618
104RPS6KA20.56962044
105IRAK30.56746210
106BMX0.56330998
107CDK90.55760773
108ILK0.55630673
109FYN0.54135650
110LYN0.54039179
111MAPK110.54022268
112RPS6KL10.52823298
113RPS6KC10.52823298
114MAP3K140.49817313
115CDC42BPA0.47601777
116PDK10.46828945
117MAP3K60.44870067
118PRKD10.44627878
119UHMK10.44532301
120MAP3K80.44366507
121DYRK30.44336306
122MAPK70.43561145
123RAF10.41362244
124ATR0.41332200
125SGK20.41085754
126MAP3K110.40719974
127PRKCQ0.40645759
128MAP2K60.40271934
129STK110.38590531
130MAPK30.38532460
131RPS6KA10.37700311
132PAK60.36884185
133RPS6KA50.36680681
134MAPK40.36293363
135PAK40.35640508
136KSR20.35313417
137CAMKK10.35291296
138MTOR0.35081639
139ICK0.34926208
140MAP3K130.34441336
141PAK10.34297126

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.68375234
2B cell receptor signaling pathway_Homo sapiens_hsa046622.67819231
3Allograft rejection_Homo sapiens_hsa053302.49701962
4DNA replication_Homo sapiens_hsa030302.39463092
5Autoimmune thyroid disease_Homo sapiens_hsa053202.36226608
6Graft-versus-host disease_Homo sapiens_hsa053322.18849452
7T cell receptor signaling pathway_Homo sapiens_hsa046602.06296499
8Acute myeloid leukemia_Homo sapiens_hsa052212.04003304
9Chronic myeloid leukemia_Homo sapiens_hsa052201.92271183
10Base excision repair_Homo sapiens_hsa034101.85362143
11Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.84639319
12Staphylococcus aureus infection_Homo sapiens_hsa051501.80046632
13Measles_Homo sapiens_hsa051621.75531830
14Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.73237276
15Type I diabetes mellitus_Homo sapiens_hsa049401.71689930
16NF-kappa B signaling pathway_Homo sapiens_hsa040641.71054565
17Osteoclast differentiation_Homo sapiens_hsa043801.67765386
18Mismatch repair_Homo sapiens_hsa034301.65863567
19Leishmaniasis_Homo sapiens_hsa051401.62303324
20Antigen processing and presentation_Homo sapiens_hsa046121.51886182
21Asthma_Homo sapiens_hsa053101.50213376
22Non-small cell lung cancer_Homo sapiens_hsa052231.50077189
23Notch signaling pathway_Homo sapiens_hsa043301.45112393
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.43819957
25Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.42488720
26Spliceosome_Homo sapiens_hsa030401.41732390
27Herpes simplex infection_Homo sapiens_hsa051681.39388246
28Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.38947988
29Intestinal immune network for IgA production_Homo sapiens_hsa046721.35683563
30Pancreatic cancer_Homo sapiens_hsa052121.28311774
31HTLV-I infection_Homo sapiens_hsa051661.27304561
32Sulfur relay system_Homo sapiens_hsa041221.27267839
33Hepatitis B_Homo sapiens_hsa051611.26935726
34Colorectal cancer_Homo sapiens_hsa052101.26127824
35Neurotrophin signaling pathway_Homo sapiens_hsa047221.24499059
36Platelet activation_Homo sapiens_hsa046111.23581026
37Ribosome_Homo sapiens_hsa030101.22541982
38Transcriptional misregulation in cancer_Homo sapiens_hsa052021.19904687
39Leukocyte transendothelial migration_Homo sapiens_hsa046701.19825313
40Jak-STAT signaling pathway_Homo sapiens_hsa046301.19766047
41Toxoplasmosis_Homo sapiens_hsa051451.19237972
42Chemokine signaling pathway_Homo sapiens_hsa040621.18585676
43Lysosome_Homo sapiens_hsa041421.18142915
44Viral carcinogenesis_Homo sapiens_hsa052031.17125901
45Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.14741577
46Viral myocarditis_Homo sapiens_hsa054161.12562304
47Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.11655206
48Endometrial cancer_Homo sapiens_hsa052131.08500409
49Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.07613487
50Lysine degradation_Homo sapiens_hsa003101.06176879
51VEGF signaling pathway_Homo sapiens_hsa043701.05719473
52Prolactin signaling pathway_Homo sapiens_hsa049171.05072769
53Apoptosis_Homo sapiens_hsa042101.05069768
54Toll-like receptor signaling pathway_Homo sapiens_hsa046201.04914681
55RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.04824809
56Salmonella infection_Homo sapiens_hsa051321.04478681
57Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.04224157
58Hematopoietic cell lineage_Homo sapiens_hsa046401.03697652
59Insulin resistance_Homo sapiens_hsa049311.02891088
60N-Glycan biosynthesis_Homo sapiens_hsa005101.01313937
61Carbohydrate digestion and absorption_Homo sapiens_hsa049731.01290775
62Pertussis_Homo sapiens_hsa051331.00719550
63Legionellosis_Homo sapiens_hsa051341.00216776
64Influenza A_Homo sapiens_hsa051640.99462573
65Pentose phosphate pathway_Homo sapiens_hsa000300.98660627
66AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.98548928
67Phagosome_Homo sapiens_hsa041450.98326127
68Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.97225083
69Rheumatoid arthritis_Homo sapiens_hsa053230.97158186
70Small cell lung cancer_Homo sapiens_hsa052220.96505828
71Malaria_Homo sapiens_hsa051440.96495162
72Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.95381850
73Systemic lupus erythematosus_Homo sapiens_hsa053220.95122160
74SNARE interactions in vesicular transport_Homo sapiens_hsa041300.94735268
75Fructose and mannose metabolism_Homo sapiens_hsa000510.93030891
76Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.91421573
77Shigellosis_Homo sapiens_hsa051310.90823787
78Thyroid hormone signaling pathway_Homo sapiens_hsa049190.90363752
79Phosphatidylinositol signaling system_Homo sapiens_hsa040700.89924253
80mTOR signaling pathway_Homo sapiens_hsa041500.87477737
81Regulation of autophagy_Homo sapiens_hsa041400.83290526
82mRNA surveillance pathway_Homo sapiens_hsa030150.78565114
83Cell cycle_Homo sapiens_hsa041100.76377903
84FoxO signaling pathway_Homo sapiens_hsa040680.74780695
85Thyroid cancer_Homo sapiens_hsa052160.74233673
86Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.72948586
87Sphingolipid signaling pathway_Homo sapiens_hsa040710.71782681
88Type II diabetes mellitus_Homo sapiens_hsa049300.71376071
89Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.70969866
90Inositol phosphate metabolism_Homo sapiens_hsa005620.70483153
91Alcoholism_Homo sapiens_hsa050340.69083847
92Epstein-Barr virus infection_Homo sapiens_hsa051690.67511522
93Longevity regulating pathway - mammal_Homo sapiens_hsa042110.67364519
94Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.66753781
95Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.66412837
96TNF signaling pathway_Homo sapiens_hsa046680.66242103
97Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.65594765
98Glioma_Homo sapiens_hsa052140.65207354
99Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.63253938
100Aldosterone synthesis and secretion_Homo sapiens_hsa049250.62592941
101Endocytosis_Homo sapiens_hsa041440.62362220
102Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.62178102
103Hepatitis C_Homo sapiens_hsa051600.62060599
104Tuberculosis_Homo sapiens_hsa051520.61340297
105Collecting duct acid secretion_Homo sapiens_hsa049660.60856843
106Maturity onset diabetes of the young_Homo sapiens_hsa049500.59652641
107Insulin signaling pathway_Homo sapiens_hsa049100.59332790
108Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.59297513
109Adipocytokine signaling pathway_Homo sapiens_hsa049200.57943329
110Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.57722765
111Other glycan degradation_Homo sapiens_hsa005110.56746590
112ABC transporters_Homo sapiens_hsa020100.55299529
113Prostate cancer_Homo sapiens_hsa052150.54567954
114MicroRNAs in cancer_Homo sapiens_hsa052060.53798910
115Glycosaminoglycan degradation_Homo sapiens_hsa005310.53190770
116MAPK signaling pathway_Homo sapiens_hsa040100.53119543
117NOD-like receptor signaling pathway_Homo sapiens_hsa046210.52482971
118Renal cell carcinoma_Homo sapiens_hsa052110.52291912
119Pathways in cancer_Homo sapiens_hsa052000.52150166
120Homologous recombination_Homo sapiens_hsa034400.50766935
121Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.50413718
122Choline metabolism in cancer_Homo sapiens_hsa052310.50105719
123cGMP-PKG signaling pathway_Homo sapiens_hsa040220.49357945
124Nucleotide excision repair_Homo sapiens_hsa034200.48000397
125AMPK signaling pathway_Homo sapiens_hsa041520.47213734
126RNA degradation_Homo sapiens_hsa030180.46982441
127Fanconi anemia pathway_Homo sapiens_hsa034600.46834772
128Glycerophospholipid metabolism_Homo sapiens_hsa005640.46330789
129Phospholipase D signaling pathway_Homo sapiens_hsa040720.45231697
130African trypanosomiasis_Homo sapiens_hsa051430.42545195
131Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.42271853
1322-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.40178390
133Fatty acid elongation_Homo sapiens_hsa000620.39187409
134Vibrio cholerae infection_Homo sapiens_hsa051100.36941721
135Galactose metabolism_Homo sapiens_hsa000520.36418408
136Synaptic vesicle cycle_Homo sapiens_hsa047210.32710789

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