PCDHGA9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)5.66770808
2locomotory exploration behavior (GO:0035641)5.59936679
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.21903114
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.11817040
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.07902776
6vocalization behavior (GO:0071625)4.69303462
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.61123323
8protein localization to synapse (GO:0035418)4.51539086
9synaptic vesicle exocytosis (GO:0016079)4.48337675
10synaptic vesicle docking involved in exocytosis (GO:0016081)4.35368924
11layer formation in cerebral cortex (GO:0021819)4.33462865
12regulation of glutamate receptor signaling pathway (GO:1900449)4.27635839
13cellular potassium ion homeostasis (GO:0030007)4.20929023
14exploration behavior (GO:0035640)4.20271682
15regulation of synaptic vesicle exocytosis (GO:2000300)4.14159297
16glutamate secretion (GO:0014047)4.14133150
17regulation of synapse structural plasticity (GO:0051823)4.08173101
18neurotransmitter-gated ion channel clustering (GO:0072578)3.98986350
19dermatan sulfate biosynthetic process (GO:0030208)3.91150344
20presynaptic membrane organization (GO:0097090)3.91026527
21regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.89193649
22dendritic spine morphogenesis (GO:0060997)3.88088532
23positive regulation of synapse maturation (GO:0090129)3.87090982
24neuron cell-cell adhesion (GO:0007158)3.84592997
25axon ensheathment in central nervous system (GO:0032291)3.79315843
26central nervous system myelination (GO:0022010)3.79315843
27L-amino acid import (GO:0043092)3.79073108
28membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.79000417
29ionotropic glutamate receptor signaling pathway (GO:0035235)3.75168356
30regulation of long-term neuronal synaptic plasticity (GO:0048169)3.72436499
31regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.70868518
32neurotransmitter secretion (GO:0007269)3.67409235
33cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.67000449
34regulation of neuronal synaptic plasticity (GO:0048168)3.65946693
35dermatan sulfate metabolic process (GO:0030205)3.65354783
36dendrite morphogenesis (GO:0048813)3.62086678
37sodium ion export (GO:0071436)3.61997113
38glutamate receptor signaling pathway (GO:0007215)3.57999279
39regulation of synaptic vesicle transport (GO:1902803)3.54340871
40regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.53701603
41long-term memory (GO:0007616)3.50070820
42cell communication by electrical coupling (GO:0010644)3.49398946
43amino acid import (GO:0043090)3.41809102
44positive regulation of membrane potential (GO:0045838)3.40008645
45regulation of dendritic spine morphogenesis (GO:0061001)3.39406030
46activation of protein kinase A activity (GO:0034199)3.37802652
47synaptic transmission, glutamatergic (GO:0035249)3.37383077
48positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.37340947
49neurotransmitter uptake (GO:0001504)3.35273423
50regulation of excitatory postsynaptic membrane potential (GO:0060079)3.27912447
51neuron-neuron synaptic transmission (GO:0007270)3.27260845
52G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.27074323
53gamma-aminobutyric acid transport (GO:0015812)3.24872240
54neuromuscular process controlling balance (GO:0050885)3.22322014
55neuron recognition (GO:0008038)3.22271335
56innervation (GO:0060384)3.20958935
57response to auditory stimulus (GO:0010996)3.20114006
58cellular sodium ion homeostasis (GO:0006883)3.19822264
59auditory behavior (GO:0031223)3.17803991
60regulation of postsynaptic membrane potential (GO:0060078)3.17101765
61cerebellar Purkinje cell differentiation (GO:0021702)3.15999136
62axonal fasciculation (GO:0007413)3.15149217
63establishment of nucleus localization (GO:0040023)3.13486502
64astrocyte differentiation (GO:0048708)3.12961205
65synaptic vesicle endocytosis (GO:0048488)3.10384722
66regulation of ARF protein signal transduction (GO:0032012)3.08812580
67potassium ion import (GO:0010107)3.07774446
68regulation of synaptic transmission, glutamatergic (GO:0051966)3.06629618
69membrane assembly (GO:0071709)3.06315987
70positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.05918222
71neuronal action potential propagation (GO:0019227)3.05735247
72postsynaptic membrane organization (GO:0001941)3.05360033
73proline transport (GO:0015824)3.05134830
74peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.97638524
75regulation of synaptic plasticity (GO:0048167)2.97442821
76chondroitin sulfate catabolic process (GO:0030207)2.97373017
77regulation of synapse maturation (GO:0090128)2.96750618
78long-term synaptic potentiation (GO:0060291)2.94595285
79membrane depolarization during action potential (GO:0086010)2.93268557
80potassium ion homeostasis (GO:0055075)2.92994440
81cerebellar granule cell differentiation (GO:0021707)2.92036441
82prepulse inhibition (GO:0060134)2.91661127
83neuromuscular process controlling posture (GO:0050884)2.90821730
84regulation of axon extension involved in axon guidance (GO:0048841)2.87751389
85nerve growth factor signaling pathway (GO:0038180)2.86276393
86membrane hyperpolarization (GO:0060081)2.85133671
87negative regulation of cytosolic calcium ion concentration (GO:0051481)2.84142223
88neurotransmitter transport (GO:0006836)2.83074020
89regulation of neurotransmitter secretion (GO:0046928)2.82362928
90synapse assembly (GO:0007416)2.81422030
91central nervous system projection neuron axonogenesis (GO:0021952)2.81217172
92neuronal ion channel clustering (GO:0045161)2.79689546
93astrocyte development (GO:0014002)2.78878477
94neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.78274358
95positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.77845489
96regulation of dendritic spine development (GO:0060998)2.76486525
97regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.73707172
98regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.73383246
99transmission of nerve impulse (GO:0019226)2.72935587
100dendritic spine organization (GO:0097061)2.72858528
101cell communication involved in cardiac conduction (GO:0086065)2.72552645
102positive regulation of synaptic transmission, GABAergic (GO:0032230)2.72179430
103membrane depolarization (GO:0051899)2.71781663
104response to histamine (GO:0034776)2.71597821
105cell migration in hindbrain (GO:0021535)2.70704655
106presynaptic membrane assembly (GO:0097105)2.69673952
107vesicle transport along microtubule (GO:0047496)2.69624121
108synapse organization (GO:0050808)2.69568360
109positive regulation of dendritic spine morphogenesis (GO:0061003)2.69406502
110negative regulation of synaptic transmission, GABAergic (GO:0032229)2.68416760
111gamma-aminobutyric acid signaling pathway (GO:0007214)2.68174447
112response to pheromone (GO:0019236)2.66210654
113metanephric tubule development (GO:0072170)2.66126959
114metanephric nephron tubule development (GO:0072234)2.66126959
115regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.65839852
116positive regulation of potassium ion transmembrane transport (GO:1901381)2.65830050
117G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.65409030
118visual learning (GO:0008542)2.65292273
119regulation of neurotransmitter transport (GO:0051588)2.64005975
120metanephric nephron epithelium development (GO:0072243)2.59185657
121negative regulation of protein localization to cell surface (GO:2000009)2.55879759
122acidic amino acid transport (GO:0015800)2.46983995
123regulation of respiratory system process (GO:0044065)2.44054690
124axon extension (GO:0048675)2.43379795
125regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.41451790
126regulation of axon guidance (GO:1902667)2.40884821
127neuromuscular synaptic transmission (GO:0007274)2.40365618
128cAMP biosynthetic process (GO:0006171)2.40122143
129cerebellar Purkinje cell layer development (GO:0021680)2.37997400
130cardiac myofibril assembly (GO:0055003)2.37325097
131myoblast fusion (GO:0007520)2.36415134
132C4-dicarboxylate transport (GO:0015740)2.35635793
133import into cell (GO:0098657)2.34517043
134metanephric epithelium development (GO:0072207)2.33376943
135regulation of neurotransmitter uptake (GO:0051580)2.32311119
136myelination in peripheral nervous system (GO:0022011)2.31696554
137peripheral nervous system axon ensheathment (GO:0032292)2.31696554
138positive regulation of axon extension (GO:0045773)2.31582256
139positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.29100437
140mechanosensory behavior (GO:0007638)2.27332767
141L-glutamate transport (GO:0015813)2.26887777
142regulation of cardiac muscle cell contraction (GO:0086004)2.25360592
143response to gravity (GO:0009629)2.24816571

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.97397158
2GBX2_23144817_ChIP-Seq_PC3_Human3.40811422
3* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.83051156
4* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.79391937
5DROSHA_22980978_ChIP-Seq_HELA_Human2.72651317
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.72589232
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.51828895
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.51828895
9ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.49287932
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.43652448
11RARB_27405468_Chip-Seq_BRAIN_Mouse2.43025443
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.38026284
13* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.32945434
14SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.32351756
15* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.30107353
16* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.27806039
17REST_21632747_ChIP-Seq_MESCs_Mouse2.26092693
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.25612852
19* EED_16625203_ChIP-ChIP_MESCs_Mouse2.17720939
20GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.16174598
21EZH2_27294783_Chip-Seq_ESCs_Mouse2.11685709
22RNF2_27304074_Chip-Seq_ESCs_Mouse2.09185187
23EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.08289425
24SUZ12_27294783_Chip-Seq_ESCs_Mouse2.01279884
25AR_21572438_ChIP-Seq_LNCaP_Human1.94051925
26TRIM28_21343339_ChIP-Seq_HEK293_Human1.93146263
27MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.82124385
28CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.81945822
29REST_18959480_ChIP-ChIP_MESCs_Mouse1.80075171
30SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.77553098
31SMAD4_21799915_ChIP-Seq_A2780_Human1.60746830
32PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.57658510
33CTBP2_25329375_ChIP-Seq_LNCAP_Human1.54185455
34SMAD_19615063_ChIP-ChIP_OVARY_Human1.50563624
35VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.48939693
36IGF1R_20145208_ChIP-Seq_DFB_Human1.48293669
37WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.45667261
38SOX2_21211035_ChIP-Seq_LN229_Gbm1.44089104
39* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.42661878
40ZNF217_24962896_ChIP-Seq_MCF-7_Human1.41781389
41PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.41724994
42IKZF1_21737484_ChIP-ChIP_HCT116_Human1.38312827
43NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.37521765
44* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.36294608
45SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36260381
46AR_19668381_ChIP-Seq_PC3_Human1.33899342
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.33719309
48ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.32186205
49STAT3_23295773_ChIP-Seq_U87_Human1.29325399
50RING1B_27294783_Chip-Seq_ESCs_Mouse1.29238160
51CTBP1_25329375_ChIP-Seq_LNCAP_Human1.27790775
52CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.27258119
53NR3C1_23031785_ChIP-Seq_PC12_Mouse1.26524263
54TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.26285609
55YAP1_20516196_ChIP-Seq_MESCs_Mouse1.25230332
56KDM2B_26808549_Chip-Seq_K562_Human1.24893309
57* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.24590722
58* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.22966541
59TP53_16413492_ChIP-PET_HCT116_Human1.22879973
60MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.21254664
61AHR_22903824_ChIP-Seq_MCF-7_Human1.20951130
62P53_22127205_ChIP-Seq_FIBROBLAST_Human1.20898781
63ARNT_22903824_ChIP-Seq_MCF-7_Human1.20273312
64CDX2_19796622_ChIP-Seq_MESCs_Mouse1.19860697
65ERG_21242973_ChIP-ChIP_JURKAT_Human1.19141348
66CJUN_26792858_Chip-Seq_BT549_Human1.18525027
67PIAS1_25552417_ChIP-Seq_VCAP_Human1.18029898
68NRF2_20460467_ChIP-Seq_MEFs_Mouse1.17888325
69NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.17888325
70TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.17859199
71POU3F2_20337985_ChIP-ChIP_501MEL_Human1.17443650
72ZNF274_21170338_ChIP-Seq_K562_Hela1.16798954
73ZFP281_18757296_ChIP-ChIP_E14_Mouse1.16346721
74RING1B_27294783_Chip-Seq_NPCs_Mouse1.16228977
75DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.15788915
76TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15528060
77AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.15408158
78TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.13542086
79AR_25329375_ChIP-Seq_VCAP_Human1.13520385
80P300_19829295_ChIP-Seq_ESCs_Human1.12639914
81TAF15_26573619_Chip-Seq_HEK293_Human1.11889408
82DNAJC2_21179169_ChIP-ChIP_NT2_Human1.11465702
83TCF4_23295773_ChIP-Seq_U87_Human1.10131940
84TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.09979928
85OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.09758944
86SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08210573
87NANOG_18555785_Chip-Seq_ESCs_Mouse1.07607960
88CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07382324
89RBPJ_22232070_ChIP-Seq_NCS_Mouse1.07062469
90EP300_21415370_ChIP-Seq_HL-1_Mouse1.06636946
91TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.06379241
92EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.05910774
93SMAD3_21741376_ChIP-Seq_HESCs_Human1.05896860
94CTNNB1_20460455_ChIP-Seq_HCT116_Human1.05280550
95ZFP57_27257070_Chip-Seq_ESCs_Mouse1.04427510
96EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.04311684
97CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.04251253
98RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.03969869
99TOP2B_26459242_ChIP-Seq_MCF-7_Human1.03624727
100TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.03259075
101SMAD4_21741376_ChIP-Seq_HESCs_Human1.02923419
102CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.02323987
103RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.02152435
104KDM2B_26808549_Chip-Seq_REH_Human1.01612603
105ZFP281_27345836_Chip-Seq_ESCs_Mouse1.01571739
106VDR_22108803_ChIP-Seq_LS180_Human0.99564795
107GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99074662
108EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.98937669
109NR3C1_21868756_ChIP-Seq_MCF10A_Human0.98219744
110SMAD3_21741376_ChIP-Seq_ESCs_Human0.96867440
111RXR_22108803_ChIP-Seq_LS180_Human0.95708670
112GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95202496
113TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91255969
114POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.91255969
115ISL1_27105846_Chip-Seq_CPCs_Mouse0.90769081
116CBX2_27304074_Chip-Seq_ESCs_Mouse0.90657802
117RUNX2_22187159_ChIP-Seq_PCA_Human0.89719481
118PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.89332506
119* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.89170622
120TP53_18474530_ChIP-ChIP_U2OS_Human0.87434808

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.97770871
2MP0003880_abnormal_central_pattern3.96142704
3MP0003635_abnormal_synaptic_transmissio3.78102514
4MP0004270_analgesia3.62367634
5MP0002063_abnormal_learning/memory/cond2.99514681
6MP0009745_abnormal_behavioral_response2.86729875
7MP0009046_muscle_twitch2.84898592
8MP0002064_seizures2.63066494
9MP0009780_abnormal_chondrocyte_physiolo2.56287634
10MP0005423_abnormal_somatic_nervous2.54643131
11MP0001486_abnormal_startle_reflex2.51213089
12MP0002822_catalepsy2.39936244
13MP0002572_abnormal_emotion/affect_behav2.36295825
14MP0002734_abnormal_mechanical_nocicepti2.31379335
15MP0001968_abnormal_touch/_nociception2.27158406
16MP0000569_abnormal_digit_pigmentation2.27059863
17MP0002272_abnormal_nervous_system2.18794091
18MP0002909_abnormal_adrenal_gland2.12260608
19MP0000778_abnormal_nervous_system1.95498242
20MP0000749_muscle_degeneration1.95027618
21MP0008569_lethality_at_weaning1.87092575
22MP0004885_abnormal_endolymph1.77789487
23MP0005503_abnormal_tendon_morphology1.75689039
24MP0002184_abnormal_innervation1.73456928
25MP0001958_emphysema1.72731383
26MP0001984_abnormal_olfaction1.72356333
27MP0002067_abnormal_sensory_capabilities1.72077705
28MP0004811_abnormal_neuron_physiology1.69854957
29MP0008438_abnormal_cutaneous_collagen1.64331871
30MP0005551_abnormal_eye_electrophysiolog1.61940837
31MP0000955_abnormal_spinal_cord1.60486336
32MP0000751_myopathy1.60301985
33MP0001440_abnormal_grooming_behavior1.57119441
34MP0005386_behavior/neurological_phenoty1.55267608
35MP0004924_abnormal_behavior1.55267608
36MP0002736_abnormal_nociception_after1.54599416
37MP0004858_abnormal_nervous_system1.52901017
38MP0003279_aneurysm1.52748483
39MP0002557_abnormal_social/conspecific_i1.52493429
40MP0002733_abnormal_thermal_nociception1.50484912
41MP0001970_abnormal_pain_threshold1.49395974
42MP0002882_abnormal_neuron_morphology1.45444918
43MP0003879_abnormal_hair_cell1.44503106
44MP0005171_absent_coat_pigmentation1.42989510
45MP0001501_abnormal_sleep_pattern1.42719068
46MP0002735_abnormal_chemical_nociception1.41938801
47MP0001299_abnormal_eye_distance/1.38046848
48MP0004215_abnormal_myocardial_fiber1.37278522
49MP0003136_yellow_coat_color1.37075580
50MP0000579_abnormal_nail_morphology1.34994881
51MP0003329_amyloid_beta_deposits1.34984090
52MP0004272_abnormal_basement_membrane1.33342130
53MP0003122_maternal_imprinting1.27312521
54MP0003283_abnormal_digestive_organ1.26842297
55MP0003950_abnormal_plasma_membrane1.26663519
56MP0003633_abnormal_nervous_system1.25922643
57MP0002066_abnormal_motor_capabilities/c1.24890562
58MP0003705_abnormal_hypodermis_morpholog1.23427861
59MP0005646_abnormal_pituitary_gland1.23176701
60MP0003787_abnormal_imprinting1.21725088
61MP0005275_abnormal_skin_tensile1.19707889
62MP0001502_abnormal_circadian_rhythm1.16999317
63MP0004145_abnormal_muscle_electrophysio1.16689413
64MP0004233_abnormal_muscle_weight1.16486380
65MP0004085_abnormal_heartbeat1.14267954
66MP0002152_abnormal_brain_morphology1.13872731
67MP0005167_abnormal_blood-brain_barrier1.13314809
68MP0002090_abnormal_vision1.12380946
69MP0003137_abnormal_impulse_conducting1.11418300
70MP0005595_abnormal_vascular_smooth1.10366842
71MP0000013_abnormal_adipose_tissue1.10217308
72MP0001177_atelectasis1.09953251
73MP0005623_abnormal_meninges_morphology1.09825572
74MP0008961_abnormal_basal_metabolism1.04213649
75MP0003631_nervous_system_phenotype1.03781302
76MP0001485_abnormal_pinna_reflex1.03520049
77MP0000631_abnormal_neuroendocrine_gland1.03470992
78MP0003045_fibrosis1.02439866
79MP0002837_dystrophic_cardiac_calcinosis1.00781532
80MP0006072_abnormal_retinal_apoptosis1.00233797
81MP0002089_abnormal_postnatal_growth/wei0.99656801
82MP0002229_neurodegeneration0.97479367
83MP0002638_abnormal_pupillary_reflex0.94693619
84MP0000762_abnormal_tongue_morphology0.94366360
85MP0005187_abnormal_penis_morphology0.93791618
86MP0003634_abnormal_glial_cell0.93472814
87MP0005409_darkened_coat_color0.91331499
88MP0004142_abnormal_muscle_tone0.90486204
89MP0005645_abnormal_hypothalamus_physiol0.90080277
90MP0000534_abnormal_ureter_morphology0.87805556
91MP0001188_hyperpigmentation0.87446706
92MP0009250_abnormal_appendicular_skeleto0.85631288
93MP0005499_abnormal_olfactory_system0.84492567
94MP0005394_taste/olfaction_phenotype0.84492567
95MP0009384_cardiac_valve_regurgitation0.84212653
96MP0001963_abnormal_hearing_physiology0.81918242
97MP0002896_abnormal_bone_mineralization0.81566499
98MP0003632_abnormal_nervous_system0.81381589
99MP0003942_abnormal_urinary_system0.81341659
100MP0004134_abnormal_chest_morphology0.81175702
101MP0005670_abnormal_white_adipose0.80758693
102MP0000920_abnormal_myelination0.80107086
103MP0002069_abnormal_eating/drinking_beha0.79210589
104MP0000462_abnormal_digestive_system0.78828154
105MP0010368_abnormal_lymphatic_system0.77321502
106MP0002752_abnormal_somatic_nervous0.76892752
107MP0005253_abnormal_eye_physiology0.76758322
108MP0001905_abnormal_dopamine_level0.75782491
109MP0006276_abnormal_autonomic_nervous0.75730863
110MP0008775_abnormal_heart_ventricle0.75089998
111MP0002249_abnormal_larynx_morphology0.72747632
112MP0005508_abnormal_skeleton_morphology0.72589741
113MP0004084_abnormal_cardiac_muscle0.72493863
114MP0010386_abnormal_urinary_bladder0.71711646
115MP0000747_muscle_weakness0.71061529
116MP0004036_abnormal_muscle_relaxation0.70939021
117MP0000428_abnormal_craniofacial_morphol0.70558606
118MP0004130_abnormal_muscle_cell0.69625229
119MP0003861_abnormal_nervous_system0.69229474
120MP0000026_abnormal_inner_ear0.68912618
121MP0002295_abnormal_pulmonary_circulatio0.68508333
122MP0008874_decreased_physiological_sensi0.67685786
123MP0005620_abnormal_muscle_contractility0.67486362
124MP0003690_abnormal_glial_cell0.65773718
125MP0002108_abnormal_muscle_morphology0.64957360
126MP0002653_abnormal_ependyma_morphology0.64696340
127MP0001943_abnormal_respiration0.64385513
128MP0001529_abnormal_vocalization0.64215641
129MP0000003_abnormal_adipose_tissue0.63306099
130MP0003385_abnormal_body_wall0.62040638
131MP0003172_abnormal_lysosome_physiology0.61093897
132MP0004484_altered_response_of0.60488147
133MP0010769_abnormal_survival0.60128189

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.19503787
2Myokymia (HP:0002411)5.01913171
3Focal seizures (HP:0007359)4.46023797
4Visual hallucinations (HP:0002367)3.85260541
5Epileptic encephalopathy (HP:0200134)3.84660759
6Action tremor (HP:0002345)3.80433194
7Progressive cerebellar ataxia (HP:0002073)3.79101710
8Absence seizures (HP:0002121)3.42432268
9Atonic seizures (HP:0010819)3.41521883
10Genetic anticipation (HP:0003743)3.34005331
11Obstructive sleep apnea (HP:0002870)3.31312120
12Febrile seizures (HP:0002373)3.19479404
13Poor eye contact (HP:0000817)3.06831314
14Broad-based gait (HP:0002136)2.99321043
15Dialeptic seizures (HP:0011146)2.94071023
16Supranuclear gaze palsy (HP:0000605)2.88811063
17Generalized tonic-clonic seizures (HP:0002069)2.87501418
18Abnormal social behavior (HP:0012433)2.84930321
19Impaired social interactions (HP:0000735)2.84930321
20Dysdiadochokinesis (HP:0002075)2.82965372
21Depression (HP:0000716)2.76018334
22Ankle clonus (HP:0011448)2.72315495
23Gaze-evoked nystagmus (HP:0000640)2.69913873
24Urinary bladder sphincter dysfunction (HP:0002839)2.68831936
25Scanning speech (HP:0002168)2.67125572
26Mutism (HP:0002300)2.66184602
27Excessive salivation (HP:0003781)2.62615382
28Drooling (HP:0002307)2.62615382
29Aqueductal stenosis (HP:0002410)2.53541574
30Akinesia (HP:0002304)2.52400371
31Dysmetric saccades (HP:0000641)2.51819573
32Increased circulating renin level (HP:0000848)2.48235345
33Impaired vibration sensation in the lower limbs (HP:0002166)2.47882267
34Prolonged QT interval (HP:0001657)2.42736801
35Truncal ataxia (HP:0002078)2.42640310
36Dysmetria (HP:0001310)2.40372409
37Papilledema (HP:0001085)2.40229792
38Urethral obstruction (HP:0000796)2.40156621
39Epileptiform EEG discharges (HP:0011182)2.39046740
40EEG with generalized epileptiform discharges (HP:0011198)2.38842377
41Macroorchidism (HP:0000053)2.34536145
42Torticollis (HP:0000473)2.34007945
43Hemiplegia (HP:0002301)2.31181123
44Bowel diverticulosis (HP:0005222)2.29776562
45Postural instability (HP:0002172)2.29590374
46Abnormality of the lower motor neuron (HP:0002366)2.28665365
47Urinary urgency (HP:0000012)2.28192190
48Bladder diverticulum (HP:0000015)2.27210411
49Popliteal pterygium (HP:0009756)2.24986639
50Megalencephaly (HP:0001355)2.22525854
51Impaired smooth pursuit (HP:0007772)2.22339643
52Neonatal short-limb short stature (HP:0008921)2.22256765
53Anxiety (HP:0000739)2.21536310
54Central scotoma (HP:0000603)2.20188815
55Stereotypic behavior (HP:0000733)2.19278537
56Hypsarrhythmia (HP:0002521)2.19104636
57Round ear (HP:0100830)2.17237722
58Hyperventilation (HP:0002883)2.16891768
59Congenital stationary night blindness (HP:0007642)2.16435397
60Abnormal eating behavior (HP:0100738)2.15034941
61Split foot (HP:0001839)2.14770103
62Hemiparesis (HP:0001269)2.13506928
63Aortic aneurysm (HP:0004942)2.12252658
64Abnormality of the diencephalon (HP:0010662)2.11985925
65Hepatoblastoma (HP:0002884)2.11699096
66Intention tremor (HP:0002080)2.10414832
67Abnormal EKG (HP:0003115)2.09680021
68Flat cornea (HP:0007720)2.09391306
69Pointed chin (HP:0000307)2.08973696
70Vascular tortuosity (HP:0004948)2.03143293
71Abnormality of binocular vision (HP:0011514)2.02903976
72Diplopia (HP:0000651)2.02903976
73Hyperacusis (HP:0010780)2.02190175
74Spastic gait (HP:0002064)2.01679188
75Hyporeflexia of lower limbs (HP:0002600)2.00971980
76Limited hip movement (HP:0008800)2.00843007
77Absent speech (HP:0001344)2.00323249
78Lower limb amyotrophy (HP:0007210)1.99230825
79Protrusio acetabuli (HP:0003179)1.98799658
80Abnormality of ocular smooth pursuit (HP:0000617)1.97172952
81Atrophic scars (HP:0001075)1.95127164
82Overriding aorta (HP:0002623)1.94761278
83Focal dystonia (HP:0004373)1.94050606
84Ventricular fibrillation (HP:0001663)1.92418268
85Fetal akinesia sequence (HP:0001989)1.91660212
86Termporal pattern (HP:0011008)1.90467915
87Insidious onset (HP:0003587)1.90467915
88Laryngomalacia (HP:0001601)1.89742909
89Calf muscle hypertrophy (HP:0008981)1.89045218
90Abnormality of the corticospinal tract (HP:0002492)1.88469928
91Arterial tortuosity (HP:0005116)1.87417678
92Renovascular hypertension (HP:0100817)1.86394726
93Syncope (HP:0001279)1.84956914
94Sudden death (HP:0001699)1.84946682
95Aplasia involving bones of the upper limbs (HP:0009823)1.83961139
96Aplasia of the phalanges of the hand (HP:0009802)1.83961139
97Aplasia involving bones of the extremities (HP:0009825)1.83961139
98Bradykinesia (HP:0002067)1.82976674
99Abnormality of the calf musculature (HP:0001430)1.82918765
100Alacrima (HP:0000522)1.82852137
101Type 1 muscle fiber predominance (HP:0003803)1.82625591
102Atrial fibrillation (HP:0005110)1.82131597
103Elfin facies (HP:0004428)1.81753997
104Inappropriate behavior (HP:0000719)1.81566760
105Neurofibrillary tangles (HP:0002185)1.79848908
106Agitation (HP:0000713)1.79718984
107Lower limb muscle weakness (HP:0007340)1.79662447
108Shallow orbits (HP:0000586)1.79582052
109Bundle branch block (HP:0011710)1.78310038
110Primary atrial arrhythmia (HP:0001692)1.76622859
111Craniofacial dystonia (HP:0012179)1.76123456
112Amyotrophic lateral sclerosis (HP:0007354)1.75749304
113Overgrowth (HP:0001548)1.75743205
114Aortic dissection (HP:0002647)1.75446580
115Cerebral inclusion bodies (HP:0100314)1.75411322
116Annular pancreas (HP:0001734)1.73896069
117Impaired vibratory sensation (HP:0002495)1.73228004
118Mitral regurgitation (HP:0001653)1.73035092
119Insomnia (HP:0100785)1.72461273
120Abnormality of the anterior chamber (HP:0000593)1.72445813
121Incomplete penetrance (HP:0003829)1.71888697
122Myotonia (HP:0002486)1.71313377
123Broad metatarsal (HP:0001783)1.70375973
124Cutaneous finger syndactyly (HP:0010554)1.69435231
125Follicular hyperkeratosis (HP:0007502)1.69376625
126Open mouth (HP:0000194)1.69098269
127Hypoventilation (HP:0002791)1.68324120
128Hypoplasia of the iris (HP:0007676)1.68152193
129Bronchomalacia (HP:0002780)1.68061689
130Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.67176243
131Sleep apnea (HP:0010535)1.65158532
132Ankyloglossia (HP:0010296)1.64178841
133Abnormality of salivation (HP:0100755)1.63891726
134Short 4th metacarpal (HP:0010044)1.63484852
135Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.63484852
136Obsessive-compulsive behavior (HP:0000722)1.63114777
137Abnormality of the ischium (HP:0003174)1.62808103
138Wrist flexion contracture (HP:0001239)1.61540996
139Pulmonic stenosis (HP:0001642)1.60275314
140Renal duplication (HP:0000075)1.59509151
141Spinal rigidity (HP:0003306)1.59283901
142Muscle hypertrophy of the lower extremities (HP:0008968)1.58995347
143Protruding tongue (HP:0010808)1.58017327
144Neoplasm of the heart (HP:0100544)1.57373266
145Shawl scrotum (HP:0000049)1.57141775
146Postural tremor (HP:0002174)1.54468323
147Turricephaly (HP:0000262)1.54096259
148Megalocornea (HP:0000485)1.53943557
149Anterior segment dysgenesis (HP:0007700)1.52271477
150Bradycardia (HP:0001662)1.50875833
151Peripheral hypomyelination (HP:0007182)1.50160365
152Complete atrioventricular canal defect (HP:0001674)1.49263939
153Hypokalemic alkalosis (HP:0001949)1.49067810
154Metabolic alkalosis (HP:0200114)1.47013437

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.01147251
2MARK13.96262301
3NTRK33.54330984
4MAP3K93.18897942
5SIK22.45457133
6MAP3K42.38608412
7PRKD32.28786962
8MINK12.20733764
9PAK62.18775760
10TNIK2.18153519
11LATS12.12802259
12PINK12.08675998
13DAPK22.06337336
14NTRK21.98125755
15FRK1.82071721
16PHKG11.77348183
17PHKG21.77348183
18CAMKK11.73173053
19NTRK11.71392032
20MAP2K71.70400872
21TAOK11.55251089
22CAMK1G1.52838059
23RIPK11.52037828
24STK38L1.51135497
25KSR21.47970043
26CDK51.46810854
27PRPF4B1.35893350
28MAPK131.30125581
29KSR11.29275621
30CASK1.29114725
31MYLK1.26298654
32MARK21.24638423
33LIMK11.23915729
34OBSCN1.21654755
35PIK3CA1.16776190
36MAP2K41.14272228
37SGK2231.14101012
38SGK4941.14101012
39LMTK21.13935618
40SIK11.13560961
41SIK31.12996530
42ROCK21.11347025
43CAMKK21.09961725
44SGK21.07667966
45PLK21.07004585
46STK381.06403908
47RET1.04032225
48CAMK1D1.02366840
49SGK31.01416912
50PAK31.00922567
51RIPK40.98518145
52TYRO30.98462990
53PTK20.97819421
54CAMK10.97485463
55PRKCH0.96785420
56CDK190.95304276
57CAMK2G0.93923304
58DAPK10.90888522
59MET0.90664979
60WNK10.90567444
61PRKCG0.89054625
62LATS20.87672434
63UHMK10.86928087
64INSRR0.86474364
65FGFR20.84190329
66MAP3K20.82413984
67CAMK2A0.80709562
68AKT30.80342011
69CDC42BPA0.80277879
70FES0.79300524
71SGK10.77597614
72PTK2B0.77558907
73CCNB10.76796603
74DMPK0.76487051
75CSNK1A1L0.76195201
76SCYL20.76083711
77MUSK0.76064622
78ALK0.75685088
79PIK3CG0.75007782
80STK110.74721710
81CAMK40.74442103
82PAK20.74185296
83MAP3K130.72672708
84STK390.70415284
85CDK180.69579240
86CDK150.69485170
87GRK50.67963860
88DDR20.67822038
89PRKD10.67554001
90ERBB20.67042616
91PKN20.66908665
92CDK140.66787956
93TAOK20.65824013
94PNCK0.65357116
95MAPK70.65281011
96CSNK1G10.62683677
97PRKD20.61413112
98RPS6KA30.60093557
99PDGFRA0.60085319
100ERBB40.59137045
101PRKCZ0.58968961
102ERBB30.58941137
103CDK11A0.58850403
104PKN10.57664052
105DYRK1A0.56308214
106CAMK2D0.53344943
107PRKCE0.53227776
108ADRBK10.52431457
109ICK0.52381898
110CAMK2B0.51545603
111MAPK100.51505473
112FYN0.50484151
113MAP3K70.49294736
114CSNK1D0.48670604
115ARAF0.48593643
116MAPK120.48348749
117PRKG10.48076360
118CSNK1G20.47648536
119NEK10.47602819
120PDK10.47511475
121FER0.46568781
122TRPM70.46118893
123ROCK10.45748848
124MAP2K10.45659197
125FGFR10.43571170
126MTOR0.43244776
127BMX0.43188644
128NEK60.43153969
129TIE10.42847757
130CSNK1G30.42663995
131DAPK30.42482731
132PDGFRB0.42437986
133RPS6KA20.41885800
134PRKAA10.41354156
135TTN0.40403103
136OXSR10.38196220
137DYRK20.35625575
138PRKG20.35357738

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.99290265
2Synaptic vesicle cycle_Homo sapiens_hsa047212.62109361
3Circadian entrainment_Homo sapiens_hsa047132.58297349
4GABAergic synapse_Homo sapiens_hsa047272.50246447
5Olfactory transduction_Homo sapiens_hsa047402.45940880
6Morphine addiction_Homo sapiens_hsa050322.36645394
7Glutamatergic synapse_Homo sapiens_hsa047242.31721822
8Long-term potentiation_Homo sapiens_hsa047202.31498243
9Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.29504758
10Insulin secretion_Homo sapiens_hsa049112.08654501
11Amphetamine addiction_Homo sapiens_hsa050312.04312331
12Salivary secretion_Homo sapiens_hsa049702.02181118
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.97914336
14Cholinergic synapse_Homo sapiens_hsa047251.96004841
15Dopaminergic synapse_Homo sapiens_hsa047281.92734522
16Aldosterone synthesis and secretion_Homo sapiens_hsa049251.85751924
17Renin secretion_Homo sapiens_hsa049241.80543037
18Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.78414627
19Gastric acid secretion_Homo sapiens_hsa049711.73415807
20Oxytocin signaling pathway_Homo sapiens_hsa049211.62950021
21ECM-receptor interaction_Homo sapiens_hsa045121.61203086
22Type II diabetes mellitus_Homo sapiens_hsa049301.57807107
23Cocaine addiction_Homo sapiens_hsa050301.55855859
24Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.51254024
25Long-term depression_Homo sapiens_hsa047301.42041092
26Taste transduction_Homo sapiens_hsa047421.40990140
27Calcium signaling pathway_Homo sapiens_hsa040201.40073298
28Axon guidance_Homo sapiens_hsa043601.39874831
29Gap junction_Homo sapiens_hsa045401.37306194
30Dilated cardiomyopathy_Homo sapiens_hsa054141.35918421
31Serotonergic synapse_Homo sapiens_hsa047261.35263729
32GnRH signaling pathway_Homo sapiens_hsa049121.34876498
33cAMP signaling pathway_Homo sapiens_hsa040241.33831946
34Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.31757791
35Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.25424178
36cGMP-PKG signaling pathway_Homo sapiens_hsa040221.20513492
37Glioma_Homo sapiens_hsa052141.20238615
38Phototransduction_Homo sapiens_hsa047441.19129420
39Estrogen signaling pathway_Homo sapiens_hsa049151.14783022
40Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.11439920
41ErbB signaling pathway_Homo sapiens_hsa040121.10863366
42Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.08685009
43Melanogenesis_Homo sapiens_hsa049161.08639627
44Phosphatidylinositol signaling system_Homo sapiens_hsa040701.08554069
45Vitamin B6 metabolism_Homo sapiens_hsa007501.06870167
46Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.03655830
47Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.03036475
48Vascular smooth muscle contraction_Homo sapiens_hsa042700.95800077
49Thyroid hormone signaling pathway_Homo sapiens_hsa049190.94276290
50Phospholipase D signaling pathway_Homo sapiens_hsa040720.94162184
51Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.92036776
52Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.90506893
53Dorso-ventral axis formation_Homo sapiens_hsa043200.89305268
54Pancreatic secretion_Homo sapiens_hsa049720.86671197
55mTOR signaling pathway_Homo sapiens_hsa041500.85735955
56Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.84498657
57Carbohydrate digestion and absorption_Homo sapiens_hsa049730.84165803
58Thyroid hormone synthesis_Homo sapiens_hsa049180.83844115
59Endometrial cancer_Homo sapiens_hsa052130.81768316
60Nitrogen metabolism_Homo sapiens_hsa009100.78240952
61Cardiac muscle contraction_Homo sapiens_hsa042600.77189432
62Melanoma_Homo sapiens_hsa052180.76875177
63MAPK signaling pathway_Homo sapiens_hsa040100.76240706
64Oocyte meiosis_Homo sapiens_hsa041140.76092056
65Choline metabolism in cancer_Homo sapiens_hsa052310.75780897
66Neurotrophin signaling pathway_Homo sapiens_hsa047220.75767946
67Rap1 signaling pathway_Homo sapiens_hsa040150.74944353
68Lysine degradation_Homo sapiens_hsa003100.74695847
69Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.72544450
70Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.71946720
71Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.71427250
72Renal cell carcinoma_Homo sapiens_hsa052110.71395316
73Glucagon signaling pathway_Homo sapiens_hsa049220.70590891
74Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.69035642
75Ras signaling pathway_Homo sapiens_hsa040140.68955893
76Longevity regulating pathway - mammal_Homo sapiens_hsa042110.67988029
77Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.65258625
78Wnt signaling pathway_Homo sapiens_hsa043100.65057445
79Circadian rhythm_Homo sapiens_hsa047100.64617874
80Protein digestion and absorption_Homo sapiens_hsa049740.64289691
81VEGF signaling pathway_Homo sapiens_hsa043700.63726823
82beta-Alanine metabolism_Homo sapiens_hsa004100.62046879
83Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.61622899
84Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.60841429
85Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60667013
86Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.60515763
87Collecting duct acid secretion_Homo sapiens_hsa049660.59995928
88Adherens junction_Homo sapiens_hsa045200.59813685
89Insulin signaling pathway_Homo sapiens_hsa049100.58836604
90Non-small cell lung cancer_Homo sapiens_hsa052230.58601583
91Vibrio cholerae infection_Homo sapiens_hsa051100.57360589
92Alcoholism_Homo sapiens_hsa050340.57139758
93MicroRNAs in cancer_Homo sapiens_hsa052060.55753485
94Basal cell carcinoma_Homo sapiens_hsa052170.54542673
95Central carbon metabolism in cancer_Homo sapiens_hsa052300.54062884
96Butanoate metabolism_Homo sapiens_hsa006500.53628373
97Bile secretion_Homo sapiens_hsa049760.53113238
98Colorectal cancer_Homo sapiens_hsa052100.52930645
99PI3K-Akt signaling pathway_Homo sapiens_hsa041510.51202871
100Sphingolipid signaling pathway_Homo sapiens_hsa040710.50737397
101Endocytosis_Homo sapiens_hsa041440.49968394
102Focal adhesion_Homo sapiens_hsa045100.49012627
103Amoebiasis_Homo sapiens_hsa051460.47589535
104Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.47515336
105Inositol phosphate metabolism_Homo sapiens_hsa005620.45942061
106Ovarian steroidogenesis_Homo sapiens_hsa049130.45122747
107Proteoglycans in cancer_Homo sapiens_hsa052050.44555901
108Mineral absorption_Homo sapiens_hsa049780.43907646
109Glycosaminoglycan degradation_Homo sapiens_hsa005310.43617994
110Hedgehog signaling pathway_Homo sapiens_hsa043400.42789301
111Prion diseases_Homo sapiens_hsa050200.42019586
112Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.41602161
113Chemokine signaling pathway_Homo sapiens_hsa040620.39642772
114Regulation of actin cytoskeleton_Homo sapiens_hsa048100.38139404
115Hippo signaling pathway_Homo sapiens_hsa043900.37663439
116Platelet activation_Homo sapiens_hsa046110.37528567
117Insulin resistance_Homo sapiens_hsa049310.37092475
118AMPK signaling pathway_Homo sapiens_hsa041520.36659002
119Tight junction_Homo sapiens_hsa045300.35788830
120Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.34866323

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