PCDHB10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)5.52491403
2locomotory exploration behavior (GO:0035641)5.41277328
3cerebral cortex radially oriented cell migration (GO:0021799)4.69454270
4synaptic vesicle exocytosis (GO:0016079)4.66774290
5cell migration in hindbrain (GO:0021535)4.64416761
6regulation of short-term neuronal synaptic plasticity (GO:0048172)4.53654169
7vocalization behavior (GO:0071625)4.46481555
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.46129129
9regulation of synapse structural plasticity (GO:0051823)4.31378796
10positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.27309372
11protein localization to synapse (GO:0035418)4.13385216
12exploration behavior (GO:0035640)4.11713589
13regulation of synaptic vesicle exocytosis (GO:2000300)4.06810925
14layer formation in cerebral cortex (GO:0021819)4.05524193
15mitochondrion transport along microtubule (GO:0047497)4.00899603
16establishment of mitochondrion localization, microtubule-mediated (GO:0034643)4.00899603
17positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.98493466
18prepulse inhibition (GO:0060134)3.94277499
19regulation of glutamate receptor signaling pathway (GO:1900449)3.89721626
20ionotropic glutamate receptor signaling pathway (GO:0035235)3.88027802
21neuron recognition (GO:0008038)3.87814778
22presynaptic membrane assembly (GO:0097105)3.87723188
23dendrite morphogenesis (GO:0048813)3.84341993
24glutamate secretion (GO:0014047)3.84273043
25* synapse assembly (GO:0007416)3.81496732
26neurotransmitter-gated ion channel clustering (GO:0072578)3.80649516
27synaptic transmission, glutamatergic (GO:0035249)3.79688578
28nonmotile primary cilium assembly (GO:0035058)3.71933846
29L-amino acid import (GO:0043092)3.70519911
30regulation of synaptic vesicle transport (GO:1902803)3.67432081
31synaptic vesicle maturation (GO:0016188)3.66560779
32regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.64595179
33glutamate receptor signaling pathway (GO:0007215)3.64254601
34innervation (GO:0060384)3.61659945
35presynaptic membrane organization (GO:0097090)3.59821336
36amino acid import (GO:0043090)3.58750239
37neuron-neuron synaptic transmission (GO:0007270)3.56679520
38postsynaptic membrane organization (GO:0001941)3.56415709
39dendritic spine morphogenesis (GO:0060997)3.48345381
40long-term synaptic potentiation (GO:0060291)3.45563455
41pyrimidine nucleobase catabolic process (GO:0006208)3.42259637
42neurotransmitter secretion (GO:0007269)3.41498236
43behavioral response to nicotine (GO:0035095)3.41459222
44axonal fasciculation (GO:0007413)3.38706156
45epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.37539503
46positive regulation of mitochondrial fission (GO:0090141)3.27495022
47cerebellar granule cell differentiation (GO:0021707)3.24127203
48regulation of neuronal synaptic plasticity (GO:0048168)3.23319693
49regulation of long-term neuronal synaptic plasticity (GO:0048169)3.22953412
50regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.22933529
51long-term memory (GO:0007616)3.20100488
52positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.17815363
53positive regulation of synapse maturation (GO:0090129)3.16721470
54startle response (GO:0001964)3.15717561
55retinal ganglion cell axon guidance (GO:0031290)3.14847798
56gamma-aminobutyric acid transport (GO:0015812)3.14536605
57* synapse organization (GO:0050808)3.12207957
58transmission of nerve impulse (GO:0019226)3.11681227
59neuronal action potential propagation (GO:0019227)3.10881139
60gamma-aminobutyric acid signaling pathway (GO:0007214)3.10860968
61regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.08921913
62membrane hyperpolarization (GO:0060081)3.07161788
63neuromuscular synaptic transmission (GO:0007274)3.06700896
64membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.03601851
65dendrite development (GO:0016358)3.03000259
66synaptic vesicle docking involved in exocytosis (GO:0016081)3.02886744
67positive regulation of synapse assembly (GO:0051965)3.02164978
68regulation of synaptic transmission, glutamatergic (GO:0051966)3.01529346
69central nervous system projection neuron axonogenesis (GO:0021952)3.01137029
70C4-dicarboxylate transport (GO:0015740)3.00615853
71mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.99241218
72positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.99241218
73axon extension involved in axon guidance (GO:0048846)2.92554011
74neuron projection extension involved in neuron projection guidance (GO:1902284)2.92554011
75regulation of excitatory postsynaptic membrane potential (GO:0060079)2.91582488
76spinal cord development (GO:0021510)2.91429870
77synaptic vesicle endocytosis (GO:0048488)2.91164417
78G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.89893543
79mating behavior (GO:0007617)2.89638084
80mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.89024050
81regulation of dendritic spine morphogenesis (GO:0061001)2.88806804
82neurotransmitter transport (GO:0006836)2.87962564
83cerebral cortex cell migration (GO:0021795)2.87524807
84regulation of synaptic plasticity (GO:0048167)2.86987317
85positive regulation of membrane potential (GO:0045838)2.86794224
86long term synaptic depression (GO:0060292)2.86098169
87regulation of postsynaptic membrane potential (GO:0060078)2.83991771
88negative regulation of axonogenesis (GO:0050771)2.82230892
89negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.78709457
90negative regulation of axon guidance (GO:1902668)2.78657680
91olfactory bulb development (GO:0021772)2.78241337
92behavioral defense response (GO:0002209)2.76680565
93behavioral fear response (GO:0001662)2.76680565
94regulation of voltage-gated calcium channel activity (GO:1901385)2.74985532
95substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.74944327
96substrate-independent telencephalic tangential migration (GO:0021826)2.74944327
97proline transport (GO:0015824)2.74935172
98regulation of neurotransmitter secretion (GO:0046928)2.74800350
99* calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.73622547
100regulation of vesicle fusion (GO:0031338)2.73476997
101neuronal ion channel clustering (GO:0045161)2.73131693
102auditory behavior (GO:0031223)2.72333017
103negative regulation of axon extension (GO:0030517)2.71179767
104regulation of axon extension involved in axon guidance (GO:0048841)2.69053521
105regulation of neurotransmitter levels (GO:0001505)2.68583999
106negative regulation of oligodendrocyte differentiation (GO:0048715)2.68453194
107limb development (GO:0060173)2.68415357
108appendage development (GO:0048736)2.68415357
109positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.68244876
110axon extension (GO:0048675)2.67674019
111nucleobase catabolic process (GO:0046113)2.66087573
112negative regulation of microtubule polymerization (GO:0031115)2.65809390
113regulation of synapse assembly (GO:0051963)2.65782306
114regulation of respiratory system process (GO:0044065)2.63758631
115* homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.63523207
116positive regulation of synaptic transmission, GABAergic (GO:0032230)2.63013591
117hippocampus development (GO:0021766)2.62899843
118regulation of neurotransmitter transport (GO:0051588)2.62832952
119ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.61761962
120positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.61581457
121short-term memory (GO:0007614)2.61317679
122establishment of mitochondrion localization (GO:0051654)2.61177221
123adult walking behavior (GO:0007628)2.60300890
124regulation of axon guidance (GO:1902667)2.59554925
125response to auditory stimulus (GO:0010996)2.59168892
126peripheral nervous system axon ensheathment (GO:0032292)2.58933277
127myelination in peripheral nervous system (GO:0022011)2.58933277
128regulation of cilium movement (GO:0003352)2.55315807
129neuron migration (GO:0001764)2.54334992
130neuron projection extension (GO:1990138)2.52216625
131intraciliary transport (GO:0042073)2.50115252
132organelle transport along microtubule (GO:0072384)2.48112160
133forebrain neuron differentiation (GO:0021879)2.45715765
134positive regulation of dendritic spine morphogenesis (GO:0061003)2.45573968
135establishment of melanosome localization (GO:0032401)2.44160260
136cytoskeleton-dependent intracellular transport (GO:0030705)2.42647095
137brain morphogenesis (GO:0048854)2.41843961
138ephrin receptor signaling pathway (GO:0048013)2.41793021
139mechanosensory behavior (GO:0007638)2.41732639
140ganglion development (GO:0061548)2.41360700
141negative regulation of synaptic transmission, GABAergic (GO:0032229)2.40394330
142neuronal stem cell maintenance (GO:0097150)2.39337660
143central nervous system neuron axonogenesis (GO:0021955)2.38851973

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.25689708
2GBX2_23144817_ChIP-Seq_PC3_Human3.78199857
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.09003060
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.06104931
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.94907810
6RBPJ_22232070_ChIP-Seq_NCS_Mouse2.67960134
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.66286729
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.66286729
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.59398319
10SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.58904150
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.57746257
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.57387972
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.45799099
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.42996626
15* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.38093610
16AR_21572438_ChIP-Seq_LNCaP_Human2.36609565
17REST_21632747_ChIP-Seq_MESCs_Mouse2.34482495
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.33816724
19EZH2_27294783_Chip-Seq_ESCs_Mouse2.17787461
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.17614135
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.09753144
22DROSHA_22980978_ChIP-Seq_HELA_Human2.09173927
23CTBP1_25329375_ChIP-Seq_LNCAP_Human2.08799997
24GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.06351967
25CTBP2_25329375_ChIP-Seq_LNCAP_Human1.99047030
26RARB_27405468_Chip-Seq_BRAIN_Mouse1.93317874
27PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.91762403
28REST_18959480_ChIP-ChIP_MESCs_Mouse1.89596313
29NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.84203367
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.82382422
31SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.81813252
32TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.80220200
33OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.77289846
34PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.76542008
35CBX2_27304074_Chip-Seq_ESCs_Mouse1.71631630
36ZNF274_21170338_ChIP-Seq_K562_Hela1.65436813
37SMAD4_21799915_ChIP-Seq_A2780_Human1.64460397
38ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.64418103
39P300_19829295_ChIP-Seq_ESCs_Human1.63258036
40HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.62380887
41RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.62266240
42TAF15_26573619_Chip-Seq_HEK293_Human1.61541555
43SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.58880181
44CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.53118931
45SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.52023823
46PIAS1_25552417_ChIP-Seq_VCAP_Human1.50394076
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.49376915
48NR3C1_23031785_ChIP-Seq_PC12_Mouse1.45444768
49TOP2B_26459242_ChIP-Seq_MCF-7_Human1.44977116
50* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.43425626
51FUS_26573619_Chip-Seq_HEK293_Human1.42919728
52RING1B_27294783_Chip-Seq_ESCs_Mouse1.37878903
53CDX2_19796622_ChIP-Seq_MESCs_Mouse1.36061320
54AR_25329375_ChIP-Seq_VCAP_Human1.35651881
55SOX2_21211035_ChIP-Seq_LN229_Gbm1.32669518
56GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.32313982
57RNF2_27304074_Chip-Seq_NSC_Mouse1.30236261
58OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.29487577
59RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.28805676
60WT1_19549856_ChIP-ChIP_CCG9911_Human1.28280370
61BMI1_23680149_ChIP-Seq_NPCS_Mouse1.25541519
62BCAT_22108803_ChIP-Seq_LS180_Human1.25229976
63* ERG_21242973_ChIP-ChIP_JURKAT_Human1.25160347
64GATA1_26923725_Chip-Seq_HPCs_Mouse1.24750411
65ARNT_22903824_ChIP-Seq_MCF-7_Human1.24223031
66RING1B_27294783_Chip-Seq_NPCs_Mouse1.23646591
67STAT3_23295773_ChIP-Seq_U87_Human1.22061448
68IGF1R_20145208_ChIP-Seq_DFB_Human1.22025882
69KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.22007504
70TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.20046964
71MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.18431177
72AHR_22903824_ChIP-Seq_MCF-7_Human1.16605044
73IKZF1_21737484_ChIP-ChIP_HCT116_Human1.15227446
74ZNF217_24962896_ChIP-Seq_MCF-7_Human1.14836175
75MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.14113272
76FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.11988941
77RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.11806373
78TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10823833
79POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.10823833
80CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.10724334
81AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.10442870
82NR3C1_21868756_ChIP-Seq_MCF10A_Human1.09742193
83VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.09697022
84AR_19668381_ChIP-Seq_PC3_Human1.09124023
85WT1_25993318_ChIP-Seq_PODOCYTE_Human1.08927012
86YAP1_20516196_ChIP-Seq_MESCs_Mouse1.06925814
87EWS_26573619_Chip-Seq_HEK293_Human1.06130819
88TCF4_23295773_ChIP-Seq_U87_Human1.05883164
89ER_23166858_ChIP-Seq_MCF-7_Human1.05608732
90MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.05438702
91TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.05420119
92UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.05070482
93PRDM14_20953172_ChIP-Seq_ESCs_Human1.04567025
94TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04044582
95RUNX2_22187159_ChIP-Seq_PCA_Human1.03400454
96POU5F1_16153702_ChIP-ChIP_HESCs_Human1.01358647
97STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.01182267
98VDR_22108803_ChIP-Seq_LS180_Human1.00930616
99TP53_18474530_ChIP-ChIP_U2OS_Human1.00527908
100RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.98797981
101ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.98231680
102EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.98191266
103TAL1_26923725_Chip-Seq_HPCs_Mouse0.97628578
104SALL1_21062744_ChIP-ChIP_HESCs_Human0.97156056
105TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.96562462
106SOX9_26525672_Chip-Seq_HEART_Mouse0.96354406
107CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95733264
108SMAD3_21741376_ChIP-Seq_ESCs_Human0.95632194
109SMAD4_21741376_ChIP-Seq_HESCs_Human0.94792144
110TBX3_20139965_ChIP-Seq_MESCs_Mouse0.94556754
111IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.94192881
112CBP_20019798_ChIP-Seq_JUKART_Human0.94192881
113TBX3_20139965_ChIP-Seq_ESCs_Mouse0.94095270
114TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.92618172
115SMAD_19615063_ChIP-ChIP_OVARY_Human0.92151144
116LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91519752
117P53_22127205_ChIP-Seq_FIBROBLAST_Human0.91010319
118EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.90884324
119TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.90380233
120MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.88941042

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.03087315
2MP0003880_abnormal_central_pattern3.90560159
3MP0003635_abnormal_synaptic_transmissio3.61223709
4MP0004270_analgesia3.43327811
5MP0002063_abnormal_learning/memory/cond2.96043508
6MP0002064_seizures2.90010142
7MP0005423_abnormal_somatic_nervous2.89779539
8MP0009745_abnormal_behavioral_response2.87604214
9MP0001968_abnormal_touch/_nociception2.75534530
10MP0002734_abnormal_mechanical_nocicepti2.65074999
11MP0000778_abnormal_nervous_system2.61645444
12MP0002572_abnormal_emotion/affect_behav2.60289449
13MP0001486_abnormal_startle_reflex2.55734898
14MP0002272_abnormal_nervous_system2.42205245
15MP0004858_abnormal_nervous_system2.37433093
16MP0002736_abnormal_nociception_after2.32971634
17MP0001529_abnormal_vocalization2.10806384
18MP0004133_heterotaxia2.10337345
19MP0009046_muscle_twitch2.07051879
20MP0001440_abnormal_grooming_behavior2.04930712
21MP0002184_abnormal_innervation2.01952023
22MP0002067_abnormal_sensory_capabilities1.95530367
23MP0006276_abnormal_autonomic_nervous1.92190914
24MP0002733_abnormal_thermal_nociception1.89983163
25MP0003121_genomic_imprinting1.88209237
26MP0000955_abnormal_spinal_cord1.87075352
27MP0005645_abnormal_hypothalamus_physiol1.84541365
28MP0008789_abnormal_olfactory_epithelium1.83941902
29MP0001984_abnormal_olfaction1.83209889
30MP0004742_abnormal_vestibular_system1.78746380
31MP0000013_abnormal_adipose_tissue1.77841477
32MP0004885_abnormal_endolymph1.76180976
33MP0005551_abnormal_eye_electrophysiolog1.72296023
34MP0001970_abnormal_pain_threshold1.69009588
35MP0002557_abnormal_social/conspecific_i1.68598769
36MP0004924_abnormal_behavior1.62984209
37MP0005386_behavior/neurological_phenoty1.62984209
38MP0004811_abnormal_neuron_physiology1.61817591
39MP0008569_lethality_at_weaning1.61189599
40MP0002882_abnormal_neuron_morphology1.59871763
41MP0003329_amyloid_beta_deposits1.55733223
42MP0003634_abnormal_glial_cell1.54735372
43MP0002735_abnormal_chemical_nociception1.54324330
44MP0003787_abnormal_imprinting1.54169200
45MP0005646_abnormal_pituitary_gland1.53530355
46MP0001502_abnormal_circadian_rhythm1.51705645
47MP0004142_abnormal_muscle_tone1.42920477
48MP0002822_catalepsy1.40672470
49MP0001485_abnormal_pinna_reflex1.40533463
50MP0001501_abnormal_sleep_pattern1.40521868
51MP0003011_delayed_dark_adaptation1.37934144
52MP0002066_abnormal_motor_capabilities/c1.37817790
53MP0003136_yellow_coat_color1.37474119
54MP0002938_white_spotting1.35882924
55MP0005187_abnormal_penis_morphology1.34909227
56MP0000920_abnormal_myelination1.34767220
57MP0000049_abnormal_middle_ear1.34714086
58MP0001905_abnormal_dopamine_level1.34593546
59MP0003690_abnormal_glial_cell1.31991954
60MP0002152_abnormal_brain_morphology1.31422716
61MP0001188_hyperpigmentation1.29951984
62MP0005409_darkened_coat_color1.28616555
63MP0003633_abnormal_nervous_system1.27296616
64MP0000537_abnormal_urethra_morphology1.24678871
65MP0002090_abnormal_vision1.24071762
66MP0000631_abnormal_neuroendocrine_gland1.23143235
67MP0009780_abnormal_chondrocyte_physiolo1.19333352
68MP0000751_myopathy1.16648143
69MP0005248_abnormal_Harderian_gland1.16003871
70MP0003631_nervous_system_phenotype1.13650083
71MP0002638_abnormal_pupillary_reflex1.07728735
72MP0002909_abnormal_adrenal_gland1.07140422
73MP0002752_abnormal_somatic_nervous1.06367920
74MP0003938_abnormal_ear_development1.06325588
75MP0005253_abnormal_eye_physiology1.03941258
76MP0002229_neurodegeneration1.03029934
77MP0003890_abnormal_embryonic-extraembry1.01613727
78MP0002233_abnormal_nose_morphology1.00985724
79MP0003755_abnormal_palate_morphology1.00484652
80MP0003632_abnormal_nervous_system0.98879177
81MP0003937_abnormal_limbs/digits/tail_de0.98682637
82MP0002751_abnormal_autonomic_nervous0.97560663
83MP0001177_atelectasis0.95973535
84MP0008877_abnormal_DNA_methylation0.95588511
85MP0006072_abnormal_retinal_apoptosis0.94550210
86MP0003122_maternal_imprinting0.93458752
87MP0002234_abnormal_pharynx_morphology0.93186640
88MP0001963_abnormal_hearing_physiology0.92293991
89MP0004145_abnormal_muscle_electrophysio0.90498230
90MP0000566_synostosis0.89240467
91MP0003879_abnormal_hair_cell0.86988807
92MP0000383_abnormal_hair_follicle0.86629475
93MP0002653_abnormal_ependyma_morphology0.83507787
94MP0005623_abnormal_meninges_morphology0.81836916
95MP0003861_abnormal_nervous_system0.81366919
96MP0002069_abnormal_eating/drinking_beha0.81191243
97MP0003385_abnormal_body_wall0.79058583
98MP0000516_abnormal_urinary_system0.78799798
99MP0005367_renal/urinary_system_phenotyp0.78799798
100MP0000534_abnormal_ureter_morphology0.78043804
101MP0003942_abnormal_urinary_system0.77900473
102MP0003119_abnormal_digestive_system0.77875762
103MP0001299_abnormal_eye_distance/0.77767762
104MP0010030_abnormal_orbit_morphology0.76526249
105MP0010386_abnormal_urinary_bladder0.76289164
106MP0000647_abnormal_sebaceous_gland0.75885661
107MP0005195_abnormal_posterior_eye0.74737338
108MP0005394_taste/olfaction_phenotype0.74371188
109MP0005499_abnormal_olfactory_system0.74371188
110MP0004085_abnormal_heartbeat0.73276847
111MP0002837_dystrophic_cardiac_calcinosis0.72211961
112MP0005171_absent_coat_pigmentation0.71619891
113MP0001943_abnormal_respiration0.71250339
114MP0005535_abnormal_body_temperature0.71116812
115MP0004215_abnormal_myocardial_fiber0.69782509
116MP0004043_abnormal_pH_regulation0.69393021
117MP0003137_abnormal_impulse_conducting0.67008280
118MP0006292_abnormal_olfactory_placode0.65816476
119MP0002102_abnormal_ear_morphology0.61628460
120MP0003183_abnormal_peptide_metabolism0.61497779
121MP0003283_abnormal_digestive_organ0.58778094
122MP0000026_abnormal_inner_ear0.58323356
123MP0004130_abnormal_muscle_cell0.58196677
124MP0010770_preweaning_lethality0.56802633
125MP0002082_postnatal_lethality0.56802633
126MP0003075_altered_response_to0.55306347

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.65523964
2Myokymia (HP:0002411)5.35023096
3Hyperventilation (HP:0002883)4.09655297
4Focal seizures (HP:0007359)4.02941742
5Epileptic encephalopathy (HP:0200134)3.82174017
6Abnormality of the corticospinal tract (HP:0002492)3.68506472
7Excessive salivation (HP:0003781)3.65705460
8Drooling (HP:0002307)3.65705460
9Progressive cerebellar ataxia (HP:0002073)3.54190229
10Action tremor (HP:0002345)3.47886449
11Congenital primary aphakia (HP:0007707)3.43832073
12Impaired vibration sensation in the lower limbs (HP:0002166)3.39638424
13Dysdiadochokinesis (HP:0002075)3.37314428
14Medial flaring of the eyebrow (HP:0010747)3.27623532
15Febrile seizures (HP:0002373)3.25916094
16Atonic seizures (HP:0010819)3.23834629
17Broad-based gait (HP:0002136)3.19482801
18Degeneration of the lateral corticospinal tracts (HP:0002314)3.15829949
19Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.15829949
20Nephrogenic diabetes insipidus (HP:0009806)3.12397916
21Visual hallucinations (HP:0002367)3.10664602
22Absence seizures (HP:0002121)2.99233619
23Pancreatic fibrosis (HP:0100732)2.98790981
24Generalized tonic-clonic seizures (HP:0002069)2.98665635
25Poor eye contact (HP:0000817)2.97767818
26Genital tract atresia (HP:0001827)2.94403107
27Vaginal atresia (HP:0000148)2.94188583
28Pheochromocytoma (HP:0002666)2.90733086
29True hermaphroditism (HP:0010459)2.90541669
30Nephronophthisis (HP:0000090)2.78539726
31Impaired social interactions (HP:0000735)2.77819900
32Abnormal social behavior (HP:0012433)2.77819900
33Absent speech (HP:0001344)2.74793374
34Neuroendocrine neoplasm (HP:0100634)2.74273301
35Dysmetria (HP:0001310)2.73545561
36Dialeptic seizures (HP:0011146)2.71227910
37Anxiety (HP:0000739)2.62963168
38Exotropia (HP:0000577)2.60802454
39Amblyopia (HP:0000646)2.59815736
40Truncal ataxia (HP:0002078)2.59384607
41Neurofibrillary tangles (HP:0002185)2.57914644
42Pancreatic cysts (HP:0001737)2.55050160
43Ankle clonus (HP:0011448)2.53437414
44Abnormal eating behavior (HP:0100738)2.51298038
45Abnormality of salivation (HP:0100755)2.50708798
46Progressive inability to walk (HP:0002505)2.49500088
47Mutism (HP:0002300)2.47839582
48Epileptiform EEG discharges (HP:0011182)2.45760090
49Abnormality of midbrain morphology (HP:0002418)2.45714785
50Molar tooth sign on MRI (HP:0002419)2.45714785
51Retinal dysplasia (HP:0007973)2.45589751
52Cortical dysplasia (HP:0002539)2.44142676
53Poor coordination (HP:0002370)2.41995786
54Blue irides (HP:0000635)2.40531069
55Short tibia (HP:0005736)2.35069879
56Open mouth (HP:0000194)2.34996740
57EEG with generalized epileptiform discharges (HP:0011198)2.34339604
58Depression (HP:0000716)2.33670534
59Urinary bladder sphincter dysfunction (HP:0002839)2.33596797
60Aplasia/Hypoplasia of the tibia (HP:0005772)2.32414311
61Rib fusion (HP:0000902)2.31044407
62Absent septum pellucidum (HP:0001331)2.30283398
63Spastic gait (HP:0002064)2.29610568
64Polyphagia (HP:0002591)2.27733886
65Cerebral inclusion bodies (HP:0100314)2.27591969
66Type II lissencephaly (HP:0007260)2.25095857
67Occipital encephalocele (HP:0002085)2.24454520
68Hand muscle atrophy (HP:0009130)2.24055823
69Supranuclear gaze palsy (HP:0000605)2.23972203
70Lissencephaly (HP:0001339)2.23688723
71Aplasia/Hypoplasia of the tongue (HP:0010295)2.23535808
72Hypsarrhythmia (HP:0002521)2.23037294
73Pachygyria (HP:0001302)2.21635416
74Hypoventilation (HP:0002791)2.20069688
75Peripheral hypomyelination (HP:0007182)2.19513593
76Scanning speech (HP:0002168)2.17104802
77Abnormality of the renal medulla (HP:0100957)2.16849357
78Hemiparesis (HP:0001269)2.16093974
79Scotoma (HP:0000575)2.14354098
80Postural instability (HP:0002172)2.14277909
81Impaired vibratory sensation (HP:0002495)2.13913161
82Limb dystonia (HP:0002451)2.13608917
83Postaxial hand polydactyly (HP:0001162)2.13267548
84Generalized hypotonia (HP:0001290)2.12879154
85Sensorimotor neuropathy (HP:0007141)2.12803679
86Intention tremor (HP:0002080)2.11776330
87Postaxial foot polydactyly (HP:0001830)2.11356341
88Macroorchidism (HP:0000053)2.11122630
89Morphological abnormality of the middle ear (HP:0008609)2.10502138
90Failure to thrive in infancy (HP:0001531)2.10457773
91Gaze-evoked nystagmus (HP:0000640)2.10217556
92Congenital stationary night blindness (HP:0007642)2.10094872
93Neoplasm of the peripheral nervous system (HP:0100007)2.10078880
94Megalencephaly (HP:0001355)2.08693198
95Stereotypic behavior (HP:0000733)2.08017685
96Optic nerve hypoplasia (HP:0000609)2.07453783
97Lower limb muscle weakness (HP:0007340)2.07286209
98Termporal pattern (HP:0011008)2.07174025
99Insidious onset (HP:0003587)2.07174025
100Inability to walk (HP:0002540)2.06959342
101Septo-optic dysplasia (HP:0100842)2.06835593
102Agitation (HP:0000713)2.05620990
103Genetic anticipation (HP:0003743)2.03938186
104Broad foot (HP:0001769)2.03106788
105Fibular aplasia (HP:0002990)2.01170590
106Hyperthyroidism (HP:0000836)2.01050795
107Aplasia/Hypoplasia of the brainstem (HP:0007362)2.00900081
108Hypoplasia of the brainstem (HP:0002365)2.00900081
109Gait ataxia (HP:0002066)1.99761330
110Torticollis (HP:0000473)1.98048867
111Aplasia/Hypoplasia of the lens (HP:0008063)1.97701908
112Narrow nasal bridge (HP:0000446)1.97112917
113Sclerocornea (HP:0000647)1.96602638
114Decreased testicular size (HP:0008734)1.94075374
115Cystic liver disease (HP:0006706)1.91694661
116Micropenis (HP:0000054)1.90824952
117Central scotoma (HP:0000603)1.89940291
118Specific learning disability (HP:0001328)1.89877731
119Incomplete penetrance (HP:0003829)1.89215765
120Hepatoblastoma (HP:0002884)1.88723841
121Gait imbalance (HP:0002141)1.88592369
122Abnormality of the septum pellucidum (HP:0007375)1.87633346
123Anterior segment dysgenesis (HP:0007700)1.86305229
124Focal dystonia (HP:0004373)1.85862079
125Renal dysplasia (HP:0000110)1.85132641
126Cutaneous finger syndactyly (HP:0010554)1.83152149
127Sleep apnea (HP:0010535)1.82555345
128Anencephaly (HP:0002323)1.80903953
129Narrow forehead (HP:0000341)1.80874412
130Relative macrocephaly (HP:0004482)1.79964091
131Overgrowth (HP:0001548)1.79716626
132Akinesia (HP:0002304)1.79280705
133Vertebral arch anomaly (HP:0008438)1.79243772
134Widely spaced teeth (HP:0000687)1.78848730
135Poor suck (HP:0002033)1.78780501
136Aplasia involving bones of the upper limbs (HP:0009823)1.77950252
137Aplasia of the phalanges of the hand (HP:0009802)1.77950252
138Aplasia involving bones of the extremities (HP:0009825)1.77950252
139Obstructive sleep apnea (HP:0002870)1.77550067
140Short foot (HP:0001773)1.77410737
141Intestinal atresia (HP:0011100)1.77327111
142Split foot (HP:0001839)1.77094287
143Thickened helices (HP:0000391)1.74878831
144Esotropia (HP:0000565)1.73908087
145Hypoplasia of the corpus callosum (HP:0002079)1.73493500
146Spastic tetraplegia (HP:0002510)1.72604898
147Abnormality of glycolysis (HP:0004366)1.72508458
148Left ventricular hypertrophy (HP:0001712)1.71349328
149Polymicrogyria (HP:0002126)1.71145962
150Cutaneous syndactyly (HP:0012725)1.70930214
151Renal hypoplasia (HP:0000089)1.70099512
152Preaxial hand polydactyly (HP:0001177)1.69909253
153Vitreoretinal degeneration (HP:0000655)1.68768655
154Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.66940647
155Anomalous pulmonary venous return (HP:0010772)1.66733273
156Aplasia/Hypoplasia of the fibula (HP:0006492)1.66663717
157Chorioretinal coloboma (HP:0000567)1.66518684
158Growth hormone deficiency (HP:0000824)1.61752081
159Anophthalmia (HP:0000528)1.60316421
160Abnormality of the intervertebral disk (HP:0005108)1.58643133
161Abnormality of the lower motor neuron (HP:0002366)1.57987385
162Abnormality of the labia minora (HP:0012880)1.56657924
163Amyotrophic lateral sclerosis (HP:0007354)1.56584025

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.11556040
2MARK14.09120353
3NTRK33.30993274
4MAP4K23.17867631
5NTRK22.81170767
6MAP3K42.73372085
7EPHA42.65589756
8MINK12.28105041
9MAP2K72.22203576
10MAPK132.10753558
11MAP3K92.04469233
12TRIM281.92820392
13TNIK1.92784752
14NTRK11.76621365
15PHKG11.68852102
16PHKG21.68852102
17PAK61.67013206
18BCKDK1.66399984
19CDK51.53391347
20PLK21.52019364
21OXSR11.45744851
22CDK191.44373461
23PRKD31.43107791
24TYRO31.42669156
25SCYL21.42559633
26NME11.40247538
27UHMK11.35457239
28MAP2K41.33955751
29FGFR21.33599893
30FES1.29738736
31MUSK1.27532091
32KSR11.21484361
33PAK31.20868924
34STK241.17480758
35KSR21.17278829
36CSNK1G11.16444085
37ARAF1.15008979
38DYRK1B1.11728291
39DYRK21.11491653
40PRKCG1.10007893
41PNCK1.06969293
42DAPK21.04962190
43PINK11.04151462
44CAMK2A1.02683448
45GRK71.02624507
46BCR1.02050839
47GRK51.02035100
48STK391.01489911
49RET1.00577030
50DYRK30.97395799
51TIE10.96864059
52DYRK1A0.96571216
53CDK140.95106342
54SIK20.94869894
55DMPK0.93071982
56LIMK10.92952338
57CDK180.92779719
58LATS20.92328690
59CCNB10.91894912
60PRPF4B0.91438854
61PKN10.89982385
62CDK150.88759470
63SGK4940.88597317
64SGK2230.88597317
65TESK10.88119233
66ROCK20.87915853
67CAMK2B0.86860306
68ERBB30.86816024
69PRKCE0.84011163
70PIM20.83456934
71CAMKK20.81537416
72ADRBK20.80961187
73PRKCH0.80095977
74FGR0.78077194
75SRPK10.76753271
76CDK11A0.76253057
77CSNK1G20.73919713
78EPHB20.72445196
79CAMK1G0.72358379
80MAP3K20.70749662
81LMTK20.67289766
82CAMK1D0.67131108
83EPHB10.64457708
84SIK30.63837261
85WNK40.63172553
86RPS6KA40.62908010
87STK38L0.62177440
88MAP3K120.61963812
89CAMK2D0.60439918
90YES10.59523159
91MARK20.59042666
92AKT30.58185946
93FER0.57248824
94BMPR1B0.57241552
95ROCK10.56588220
96FYN0.55313487
97ADRBK10.55217449
98PRKD20.53602377
99CSNK1A1L0.52499011
100WNK30.52459434
101PRKCZ0.51874006
102CAMKK10.51552252
103FRK0.50762122
104CAMK2G0.50454353
105PTK2B0.49770796
106SGK20.49297311
107MAP3K60.44135200
108CSNK1G30.42529502
109RAF10.42052353
110GRK10.41231288
111MOS0.41013711
112EPHA30.40882040
113ERBB40.40659159
114CSNK1A10.40584641
115SRC0.40135039
116PRKG10.40112027
117PRKACA0.39951088
118RPS6KA20.39208723
119PDGFRB0.38989045
120PTK20.38591270
121MAPK120.38047427
122RPS6KA30.37758086
123CAMK10.37524000
124ERBB20.37456208
125CSNK1D0.36721484
126PRKAA10.36463735
127DAPK10.36443574
128STK380.36373787
129CSNK1E0.36321151
130PRKACB0.36272809
131MAPK100.35773640
132MAPK90.35506719

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.51988866
2Synaptic vesicle cycle_Homo sapiens_hsa047213.01517943
3GABAergic synapse_Homo sapiens_hsa047272.73338581
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.64710982
5Glutamatergic synapse_Homo sapiens_hsa047242.58748529
6Circadian entrainment_Homo sapiens_hsa047132.43587897
7Morphine addiction_Homo sapiens_hsa050322.34773273
8Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.23130703
9Olfactory transduction_Homo sapiens_hsa047402.03303289
10Dopaminergic synapse_Homo sapiens_hsa047282.00814407
11Cholinergic synapse_Homo sapiens_hsa047251.95771119
12Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.90569625
13Amphetamine addiction_Homo sapiens_hsa050311.89935225
14Long-term potentiation_Homo sapiens_hsa047201.88721084
15Salivary secretion_Homo sapiens_hsa049701.81891635
16Collecting duct acid secretion_Homo sapiens_hsa049661.77480910
17Serotonergic synapse_Homo sapiens_hsa047261.73394240
18Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.71829274
19Long-term depression_Homo sapiens_hsa047301.71268278
20Insulin secretion_Homo sapiens_hsa049111.63578062
21Renin secretion_Homo sapiens_hsa049241.63349972
22Gastric acid secretion_Homo sapiens_hsa049711.60116254
23Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.59945760
24Cocaine addiction_Homo sapiens_hsa050301.59244463
25Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.54834563
26Axon guidance_Homo sapiens_hsa043601.51120009
27Taste transduction_Homo sapiens_hsa047421.40786739
28Aldosterone synthesis and secretion_Homo sapiens_hsa049251.39507768
29Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.38956198
30Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.38293576
31Vibrio cholerae infection_Homo sapiens_hsa051101.33393762
32Gap junction_Homo sapiens_hsa045401.31967764
33Oxytocin signaling pathway_Homo sapiens_hsa049211.31150583
34Protein export_Homo sapiens_hsa030601.31061816
35Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.23206351
36Oxidative phosphorylation_Homo sapiens_hsa001901.19402966
37Calcium signaling pathway_Homo sapiens_hsa040201.18542276
38GnRH signaling pathway_Homo sapiens_hsa049121.17824592
39Basal cell carcinoma_Homo sapiens_hsa052171.17739787
40Dorso-ventral axis formation_Homo sapiens_hsa043201.17124352
41Hippo signaling pathway_Homo sapiens_hsa043901.16267263
42Phototransduction_Homo sapiens_hsa047441.13802266
43Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.09325501
44Cardiac muscle contraction_Homo sapiens_hsa042601.07810001
45Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.07105882
46Butanoate metabolism_Homo sapiens_hsa006501.05354720
47Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.04765524
48Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.01764131
49Alzheimers disease_Homo sapiens_hsa050101.01064050
50Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.00520865
51cAMP signaling pathway_Homo sapiens_hsa040241.00352906
52ErbB signaling pathway_Homo sapiens_hsa040120.99174017
53Estrogen signaling pathway_Homo sapiens_hsa049150.95332554
54Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.92716771
55Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.89296105
56Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.87843750
57Parkinsons disease_Homo sapiens_hsa050120.87219302
58Sulfur relay system_Homo sapiens_hsa041220.84600323
59Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.83680799
60Glioma_Homo sapiens_hsa052140.83667301
61Steroid biosynthesis_Homo sapiens_hsa001000.83648374
62Type II diabetes mellitus_Homo sapiens_hsa049300.82313949
63Dilated cardiomyopathy_Homo sapiens_hsa054140.81811233
64Melanogenesis_Homo sapiens_hsa049160.81462956
65Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.77951704
66cGMP-PKG signaling pathway_Homo sapiens_hsa040220.76347063
67Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.75359302
68Basal transcription factors_Homo sapiens_hsa030220.73909441
69Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.73381571
70Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.73030036
71Nitrogen metabolism_Homo sapiens_hsa009100.72541195
72Fatty acid elongation_Homo sapiens_hsa000620.71590709
73Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.71152741
74Vascular smooth muscle contraction_Homo sapiens_hsa042700.70783686
75Phospholipase D signaling pathway_Homo sapiens_hsa040720.69876696
76Thyroid hormone synthesis_Homo sapiens_hsa049180.69178842
77SNARE interactions in vesicular transport_Homo sapiens_hsa041300.67317550
78Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.67011524
79Sphingolipid signaling pathway_Homo sapiens_hsa040710.63077199
80Phosphatidylinositol signaling system_Homo sapiens_hsa040700.62595265
81Wnt signaling pathway_Homo sapiens_hsa043100.62275569
82Sulfur metabolism_Homo sapiens_hsa009200.61563069
83Pancreatic secretion_Homo sapiens_hsa049720.60146449
84AMPK signaling pathway_Homo sapiens_hsa041520.57749209
85Ras signaling pathway_Homo sapiens_hsa040140.56995759
86Choline metabolism in cancer_Homo sapiens_hsa052310.56989728
87Vitamin B6 metabolism_Homo sapiens_hsa007500.56271613
88Endometrial cancer_Homo sapiens_hsa052130.55309275
89Renal cell carcinoma_Homo sapiens_hsa052110.55043312
90Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.54316257
91Alcoholism_Homo sapiens_hsa050340.53810979
92MAPK signaling pathway_Homo sapiens_hsa040100.51704569
93Rap1 signaling pathway_Homo sapiens_hsa040150.51192478
94Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.50450575
95Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.50023791
96Circadian rhythm_Homo sapiens_hsa047100.49659921
97Huntingtons disease_Homo sapiens_hsa050160.49406510
98Selenocompound metabolism_Homo sapiens_hsa004500.48971991
99Ether lipid metabolism_Homo sapiens_hsa005650.47072260
100African trypanosomiasis_Homo sapiens_hsa051430.46761846
101Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.46613466
102Protein digestion and absorption_Homo sapiens_hsa049740.45174700
103ECM-receptor interaction_Homo sapiens_hsa045120.44431188
104Phagosome_Homo sapiens_hsa041450.44218724
105Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.44124676
106Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.43514185
107Ovarian steroidogenesis_Homo sapiens_hsa049130.43246318
108Bile secretion_Homo sapiens_hsa049760.43207369
109Thyroid hormone signaling pathway_Homo sapiens_hsa049190.41480574
110Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.39855201
111Notch signaling pathway_Homo sapiens_hsa043300.39643167
112Hedgehog signaling pathway_Homo sapiens_hsa043400.39451723
113Peroxisome_Homo sapiens_hsa041460.38466803
114Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.38417748
115Rheumatoid arthritis_Homo sapiens_hsa053230.38130360
116Prion diseases_Homo sapiens_hsa050200.37628834
117Regulation of autophagy_Homo sapiens_hsa041400.36397767
118Tight junction_Homo sapiens_hsa045300.35954939
119Arginine and proline metabolism_Homo sapiens_hsa003300.35018351
120Neurotrophin signaling pathway_Homo sapiens_hsa047220.34704203
121Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.34284976
122Colorectal cancer_Homo sapiens_hsa052100.33177243
123TGF-beta signaling pathway_Homo sapiens_hsa043500.33083570
124Glucagon signaling pathway_Homo sapiens_hsa049220.32566096
125VEGF signaling pathway_Homo sapiens_hsa043700.31934445
126Oocyte meiosis_Homo sapiens_hsa041140.31340968
127Endocytosis_Homo sapiens_hsa041440.30675639

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »