PARP8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative T cell selection (GO:0043383)5.19098293
2regulation of gamma-delta T cell differentiation (GO:0045586)4.93018661
3regulation of gamma-delta T cell activation (GO:0046643)4.89359817
4response to interleukin-15 (GO:0070672)4.81309281
5cellular response to interleukin-15 (GO:0071350)4.77113900
6activated T cell proliferation (GO:0050798)4.75525064
7antigen processing and presentation of endogenous antigen (GO:0019883)4.63354027
8antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.61051655
9positive T cell selection (GO:0043368)4.57839109
10antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.54516949
11antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.54516949
12positive thymic T cell selection (GO:0045059)4.44904007
13negative regulation of lymphocyte mediated immunity (GO:0002707)4.24198274
14cellular extravasation (GO:0045123)4.19588648
15negative regulation of T cell mediated immunity (GO:0002710)4.17893425
16NIK/NF-kappaB signaling (GO:0038061)4.15315237
17detection of molecule of bacterial origin (GO:0032490)4.14615706
18negative regulation of phagocytosis (GO:0050765)4.01463621
19detection of other organism (GO:0098543)3.92929478
20microglial cell activation (GO:0001774)3.91513396
21T cell selection (GO:0045058)3.87734306
22macrophage activation involved in immune response (GO:0002281)3.86267118
23neutrophil mediated immunity (GO:0002446)3.84338689
24detection of external biotic stimulus (GO:0098581)3.72452138
25negative regulation of interleukin-12 production (GO:0032695)3.69210554
26regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.67504616
27regulation of alpha-beta T cell proliferation (GO:0046640)3.65732567
28negative regulation of leukocyte mediated immunity (GO:0002704)3.64104349
29positive regulation of gamma-delta T cell activation (GO:0046645)3.61658178
30positive regulation of B cell differentiation (GO:0045579)3.58818317
31detection of bacterium (GO:0016045)3.57325151
32positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.55736587
33thymic T cell selection (GO:0045061)3.55048984
34tolerance induction (GO:0002507)3.47626735
35neutrophil activation involved in immune response (GO:0002283)3.46279332
36regulation of B cell receptor signaling pathway (GO:0050855)3.45038658
37antigen processing and presentation via MHC class Ib (GO:0002475)3.42090985
38regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.41369996
39regulation of natural killer cell mediated immunity (GO:0002715)3.41369996
40immunoglobulin mediated immune response (GO:0016064)3.35982767
41regulation of tolerance induction (GO:0002643)3.34546790
42regulation of B cell differentiation (GO:0045577)3.34293800
43regulation of T cell tolerance induction (GO:0002664)3.32270007
44regulation of T cell mediated cytotoxicity (GO:0001914)3.31680354
45positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.31512633
46detection of biotic stimulus (GO:0009595)3.30970803
47regulation of regulatory T cell differentiation (GO:0045589)3.30330096
48hepatocyte apoptotic process (GO:0097284)3.27604452
49response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.27121252
50response to host immune response (GO:0052572)3.27121252
51myeloid leukocyte mediated immunity (GO:0002444)3.25648371
52macrophage activation (GO:0042116)3.24561684
53positive regulation of alpha-beta T cell proliferation (GO:0046641)3.22126380
54negative regulation of adaptive immune response based on somatic recombination of immune receptors b3.18897642
55antigen receptor-mediated signaling pathway (GO:0050851)3.18076037
56positive regulation of tolerance induction (GO:0002645)3.17773142
57negative regulation of cell killing (GO:0031342)3.15208794
58negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.15208794
59regulation of RIG-I signaling pathway (GO:0039535)3.14884194
60positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.14640990
61response to muramyl dipeptide (GO:0032495)3.14428352
62cellular response to interferon-beta (GO:0035458)3.13989103
63positive regulation of T cell mediated cytotoxicity (GO:0001916)3.13121245
64regulation of leukocyte mediated cytotoxicity (GO:0001910)3.11517387
65mast cell activation (GO:0045576)3.09051532
66interferon-gamma-mediated signaling pathway (GO:0060333)3.06629706
67T cell receptor signaling pathway (GO:0050852)3.06312608
68neutrophil activation (GO:0042119)3.03901418
69negative regulation of adaptive immune response (GO:0002820)3.02231947
70Arp2/3 complex-mediated actin nucleation (GO:0034314)3.00196271
71response to host (GO:0075136)2.99977662
72response to host defenses (GO:0052200)2.99977662
73response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.99977662
74positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.99476529
75negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.97760487
76defense response to protozoan (GO:0042832)2.95411863
77response to protozoan (GO:0001562)2.93090077
78regulation of interferon-alpha production (GO:0032647)2.92924230
79response to peptidoglycan (GO:0032494)2.92529180
80B cell receptor signaling pathway (GO:0050853)2.90523692
81leukocyte mediated cytotoxicity (GO:0001909)2.90503128
82positive regulation of natural killer cell mediated immunity (GO:0002717)2.88878862
83positive regulation of antigen processing and presentation (GO:0002579)2.88415385
84regulation of cell killing (GO:0031341)2.87082949
85positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.86192503
86myeloid dendritic cell activation (GO:0001773)2.84202036
87chaperone mediated protein folding requiring cofactor (GO:0051085)2.82332434
88regulation of interleukin-12 biosynthetic process (GO:0045075)2.82178653
89mature B cell differentiation (GO:0002335)2.81533889
90negative regulation of B cell proliferation (GO:0030889)2.76720929
91cellular response to type I interferon (GO:0071357)2.74842348
92type I interferon signaling pathway (GO:0060337)2.74842348
93response to type I interferon (GO:0034340)2.74520968
94T cell migration (GO:0072678)2.74179887
95cellular response to zinc ion (GO:0071294)2.74066645
96B cell homeostasis (GO:0001782)2.71403253
97regulation of necroptotic process (GO:0060544)2.69890910
98positive regulation by symbiont of host defense response (GO:0052509)2.68638022
99modulation by symbiont of host defense response (GO:0052031)2.68638022
100modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.68638022
101modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.68638022
102positive regulation by organism of defense response of other organism involved in symbiotic interact2.68638022
103modulation by symbiont of host immune response (GO:0052553)2.68638022
104granulocyte activation (GO:0036230)2.68594456
105respiratory burst (GO:0045730)2.65129223
106regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.65068621
107interferon-gamma production (GO:0032609)2.64720602
108regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.63317930
109regulation of T cell receptor signaling pathway (GO:0050856)2.62879549
110mature B cell differentiation involved in immune response (GO:0002313)2.59424127
111regulation of antigen processing and presentation (GO:0002577)2.58659506
112dendritic cell differentiation (GO:0097028)2.58627019
113necroptotic process (GO:0070266)2.57912425
114regulation of dendritic cell antigen processing and presentation (GO:0002604)2.55332060
115response to interferon-beta (GO:0035456)2.55161622
116actin nucleation (GO:0045010)2.52946696
117regulation of interferon-beta biosynthetic process (GO:0045357)2.52680293
118regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.49895963
119negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.48258627
120germinal center formation (GO:0002467)2.47708593
121myeloid dendritic cell differentiation (GO:0043011)2.44758536
122leukocyte degranulation (GO:0043299)2.42356902
123definitive hemopoiesis (GO:0060216)2.41237392
124myeloid cell activation involved in immune response (GO:0002275)2.40557625
125regulation of mast cell activation (GO:0033003)2.40027827
126T cell homeostasis (GO:0043029)2.39824528
127megakaryocyte development (GO:0035855)2.38855198
128positive regulation of interferon-beta production (GO:0032728)2.38393630
129natural killer cell mediated immunity (GO:0002228)2.38092698
130natural killer cell mediated cytotoxicity (GO:0042267)2.38092698
131negative regulation of granulocyte differentiation (GO:0030853)2.37494129
132positive regulation of granulocyte differentiation (GO:0030854)2.34453672
133endosome to pigment granule transport (GO:0043485)2.34292874
134endosome to melanosome transport (GO:0035646)2.34292874
135regulation of mast cell degranulation (GO:0043304)2.32743827
136leukocyte aggregation (GO:0070486)2.32377389
137negative thymic T cell selection (GO:0045060)2.32034596
138B cell mediated immunity (GO:0019724)2.31105897
139fucose catabolic process (GO:0019317)2.30129160
140L-fucose metabolic process (GO:0042354)2.30129160
141L-fucose catabolic process (GO:0042355)2.30129160
142lymphocyte homeostasis (GO:0002260)2.29771891
143angiogenesis involved in wound healing (GO:0060055)2.29519931
144positive regulation of protein import into nucleus, translocation (GO:0033160)2.29473909
145dendritic cell chemotaxis (GO:0002407)2.28703955
146Golgi transport vesicle coating (GO:0048200)2.28544490
147COPI coating of Golgi vesicle (GO:0048205)2.28544490
148telomere maintenance via recombination (GO:0000722)2.27015480
149programmed necrotic cell death (GO:0097300)2.26421632
150regulation of response to interferon-gamma (GO:0060330)2.26387995
151dendritic cell migration (GO:0036336)2.26304216
152myeloid leukocyte activation (GO:0002274)2.25777437
153regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.25569841
154positive regulation of interferon-alpha production (GO:0032727)2.25262917

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.26159029
2EGR1_19374776_ChIP-ChIP_THP-1_Human4.60221380
3IRF8_22096565_ChIP-ChIP_GC-B_Human4.52630292
4* IRF8_21731497_ChIP-ChIP_J774_Mouse3.61753462
5MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.58125268
6* IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.54770626
7FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.51358664
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.32533551
9* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.97897163
10SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.81010887
11GATA1_22025678_ChIP-Seq_K562_Human2.77516284
12SCL_19346495_ChIP-Seq_HPC-7_Human2.74929958
13* SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.73049470
14* IRF8_27001747_Chip-Seq_BMDM_Mouse2.73010320
15STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.58606621
16SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.57661558
17* SPI1_23547873_ChIP-Seq_NB4_Human2.53712571
18* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.48354658
19ELF1_17652178_ChIP-ChIP_JURKAT_Human2.38974918
20ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.35742757
21MYC_22102868_ChIP-Seq_BL_Human2.29113683
22NOTCH1_21737748_ChIP-Seq_TLL_Human2.24834471
23VDR_21846776_ChIP-Seq_THP-1_Human2.21310730
24* MYB_26560356_Chip-Seq_TH2_Human2.19131433
25IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.17927029
26RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.16598040
27SFPI1_20887958_ChIP-Seq_HPC-7_Mouse2.08438015
28CIITA_25753668_ChIP-Seq_RAJI_Human2.07182620
29E2F4_17652178_ChIP-ChIP_JURKAT_Human2.05500311
30* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.02717311
31STAT4_19710469_ChIP-ChIP_TH1__Mouse2.01794312
32FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.99009036
33VDR_24763502_ChIP-Seq_THP-1_Human1.93640226
34MYB_26560356_Chip-Seq_TH1_Human1.91423959
35VDR_24787735_ChIP-Seq_THP-1_Human1.85056768
36BRD4_27068464_Chip-Seq_AML-cells_Mouse1.82630535
37BP1_19119308_ChIP-ChIP_Hs578T_Human1.80649008
38MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.78766324
39MAF_26560356_Chip-Seq_TH1_Human1.75497002
40HOXB4_20404135_ChIP-ChIP_EML_Mouse1.70733457
41FOXM1_23109430_ChIP-Seq_U2OS_Human1.69716553
42RUNX1_22412390_ChIP-Seq_EML_Mouse1.69485075
43VDR_23849224_ChIP-Seq_CD4+_Human1.68807068
44STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.67754152
45FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.66900722
46SPI1_23127762_ChIP-Seq_K562_Human1.64293871
47CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.61725876
48ERG_20887958_ChIP-Seq_HPC-7_Mouse1.61650064
49RUNX_20019798_ChIP-Seq_JUKART_Human1.58254176
50TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.57520296
51GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.52462189
52NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.47502582
53GATA3_27048872_Chip-Seq_THYMUS_Human1.46079088
54PU_27001747_Chip-Seq_BMDM_Mouse1.45145686
55LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.43963636
56PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.43317267
57NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.41547982
58LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.41234689
59NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.40893457
60SMAD_19615063_ChIP-ChIP_OVARY_Human1.37916083
61UTX_26944678_Chip-Seq_JUKART_Human1.37827172
62FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.35849985
63* TCF7_22412390_ChIP-Seq_EML_Mouse1.34408037
64FOXP3_21729870_ChIP-Seq_TREG_Human1.33496950
65E2F1_21310950_ChIP-Seq_MCF-7_Human1.33083439
66GABP_17652178_ChIP-ChIP_JURKAT_Human1.30125122
67TFEB_21752829_ChIP-Seq_HELA_Human1.27147105
68GATA3_26560356_Chip-Seq_TH2_Human1.26811001
69ELK1_19687146_ChIP-ChIP_HELA_Human1.26252827
70FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.26012342
71RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.23578070
72EST1_17652178_ChIP-ChIP_JURKAT_Human1.21447230
73KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.19761406
74GATA1_19941827_ChIP-Seq_MEL_Mouse1.16188464
75GATA2_22383799_ChIP-Seq_G1ME_Mouse1.14277358
76GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.11909748
77E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.10619189
78FLI1_27457419_Chip-Seq_LIVER_Mouse1.10256733
79TP63_19390658_ChIP-ChIP_HaCaT_Human1.08181968
80* SMRT_27268052_Chip-Seq_Bcells_Human1.06148906
81MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.04979749
82GATA1_22383799_ChIP-Seq_G1ME_Mouse1.04653692
83Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.04096371
84TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.01650645
85JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.01476272
86BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.00942211
87GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.00561058
88PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.99494416
89VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.99286975
90SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98927113
91DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.97279860
92CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.94979036
93VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.94775118
94EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.94375057
95CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.93681694
96GATA2_21666600_ChIP-Seq_HMVEC_Human0.93117966
97RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.91723010
98NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.90966484
99GATA3_26560356_Chip-Seq_TH1_Human0.89470663
100KDM5A_27292631_Chip-Seq_BREAST_Human0.89147369
101YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.89073289
102SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.89036415
103ETS1_20019798_ChIP-Seq_JURKAT_Human0.88758687
104FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86837849
105CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.86273245
106KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.85909754
107PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.85287978
108KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.85077191
109ETS1_22383799_ChIP-Seq_G1ME_Mouse0.84878757
110CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.84662235
111CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.84581156
112GATA2_19941826_ChIP-Seq_K562_Human0.83693543
113MAF_26560356_Chip-Seq_TH2_Human0.83381232
114KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.83274141
115* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.82796208
116GATA1_19941826_ChIP-Seq_K562_Human0.82534805
117CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.82399495
118GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81101630
119GABP_19822575_ChIP-Seq_HepG2_Human0.81013036
120E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.80703937
121SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.80468812
122PCGF2_27294783_Chip-Seq_ESCs_Mouse0.79319454
123EZH2_27294783_Chip-Seq_NPCs_Mouse0.78341954
124MYC_18555785_ChIP-Seq_MESCs_Mouse0.78214937
125POU3F2_20337985_ChIP-ChIP_501MEL_Human0.77269549
126TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.77091090
127PCGF2_27294783_Chip-Seq_NPCs_Mouse0.76907929
128CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.76693825
129PRDM14_20953172_ChIP-Seq_ESCs_Human0.75532572
130KDM2B_26808549_Chip-Seq_DND41_Human0.74148686
131NFE2_27457419_Chip-Seq_LIVER_Mouse0.73741243
132SUZ12_27294783_Chip-Seq_NPCs_Mouse0.73673662
133BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.72242745
134PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.71028996
135GATA1_19941827_ChIP-Seq_MEL86_Mouse0.70628197
136OCT4_21477851_ChIP-Seq_ESCs_Mouse0.70542052
137ER_23166858_ChIP-Seq_MCF-7_Human0.70129546

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002396_abnormal_hematopoietic_system4.01667260
2MP0001835_abnormal_antigen_presentation3.93260575
3MP0002166_altered_tumor_susceptibility2.76673028
4MP0000685_abnormal_immune_system2.65526451
5MP0005671_abnormal_response_to2.55596659
6MP0003183_abnormal_peptide_metabolism2.49237167
7MP0002148_abnormal_hypersensitivity_rea2.47635969
8MP0001800_abnormal_humoral_immune2.38722898
9MP0002419_abnormal_innate_immunity2.37671358
10MP0006082_CNS_inflammation2.36786901
11MP0002452_abnormal_antigen_presenting2.35262940
12MP0003172_abnormal_lysosome_physiology2.33613067
13MP0000569_abnormal_digit_pigmentation2.33588676
14MP0005000_abnormal_immune_tolerance2.32466349
15MP0004808_abnormal_hematopoietic_stem2.32145770
16MP0003436_decreased_susceptibility_to2.31577517
17MP0008057_abnormal_DNA_replication2.31288973
18MP0003693_abnormal_embryo_hatching2.30810234
19MP0001790_abnormal_immune_system2.28144183
20MP0005387_immune_system_phenotype2.28144183
21MP0002006_tumorigenesis2.27433552
22MP0002723_abnormal_immune_serum2.25492627
23MP0002420_abnormal_adaptive_immunity2.25266853
24MP0001819_abnormal_immune_cell2.24512664
25MP0009785_altered_susceptibility_to2.17946229
26MP0002398_abnormal_bone_marrow2.12221398
27MP0005025_abnormal_response_to2.12002703
28MP0003763_abnormal_thymus_physiology2.10497660
29MP0000015_abnormal_ear_pigmentation2.04115311
30MP0004510_myositis2.04011692
31MP0005174_abnormal_tail_pigmentation1.99612074
32MP0005058_abnormal_lysosome_morphology1.98801996
33MP0002009_preneoplasia1.97312070
34MP0000716_abnormal_immune_system1.91752467
35MP0004381_abnormal_hair_follicle1.87816342
36MP0005464_abnormal_platelet_physiology1.83822719
37MP0001545_abnormal_hematopoietic_system1.78904685
38MP0005397_hematopoietic_system_phenotyp1.78904685
39MP0010094_abnormal_chromosome_stability1.74516658
40MP0002405_respiratory_system_inflammati1.71189670
41MP0008007_abnormal_cellular_replicative1.70659521
42MP0002429_abnormal_blood_cell1.60993551
43MP0000689_abnormal_spleen_morphology1.60308832
44MP0002877_abnormal_melanocyte_morpholog1.59254972
45MP0003303_peritoneal_inflammation1.59251570
46MP0002722_abnormal_immune_system1.57912992
47MP0005310_abnormal_salivary_gland1.57766531
48MP0000465_gastrointestinal_hemorrhage1.56523342
49MP0001873_stomach_inflammation1.55243313
50MP0003111_abnormal_nucleus_morphology1.52683181
51MP0001853_heart_inflammation1.51834971
52MP0009333_abnormal_splenocyte_physiolog1.50938437
53MP0008058_abnormal_DNA_repair1.50134670
54MP0003300_gastrointestinal_ulcer1.44760837
55MP0000703_abnormal_thymus_morphology1.44051765
56MP0003866_abnormal_defecation1.41424224
57MP0003077_abnormal_cell_cycle1.41317359
58MP0010155_abnormal_intestine_physiology1.40101464
59MP0004883_abnormal_blood_vessel1.39599820
60MP0000490_abnormal_crypts_of1.35959749
61MP0010307_abnormal_tumor_latency1.35304447
62MP0001533_abnormal_skeleton_physiology1.35116941
63MP0001845_abnormal_inflammatory_respons1.34236867
64MP0009764_decreased_sensitivity_to1.33578784
65MP0005451_abnormal_body_composition1.33553771
66MP0002132_abnormal_respiratory_system1.33123343
67MP0003787_abnormal_imprinting1.32185733
68MP0003724_increased_susceptibility_to1.23804850
69MP0009278_abnormal_bone_marrow1.23470377
70MP0002095_abnormal_skin_pigmentation1.23344800
71MP0000858_altered_metastatic_potential1.17792550
72MP0005075_abnormal_melanosome_morpholog1.14902212
73MP0001986_abnormal_taste_sensitivity1.11737734
74MP0002163_abnormal_gland_morphology1.09864831
75MP0003656_abnormal_erythrocyte_physiolo1.08498718
76MP0004130_abnormal_muscle_cell1.07659904
77MP0004947_skin_inflammation1.03897015
78MP0003191_abnormal_cellular_cholesterol1.00912029
79MP0005379_endocrine/exocrine_gland_phen1.00692810
80MP0003690_abnormal_glial_cell0.97045109
81MP0003448_altered_tumor_morphology0.96590117
82MP0002019_abnormal_tumor_incidence0.95573546
83MP0002693_abnormal_pancreas_physiology0.95106695
84MP0005164_abnormal_response_to0.94936673
85MP0003045_fibrosis0.92835142
86MP0000371_diluted_coat_color0.92495486
87MP0002928_abnormal_bile_duct0.91128826
88MP0008469_abnormal_protein_level0.88110097
89MP0009763_increased_sensitivity_to0.87680207
90MP0004957_abnormal_blastocyst_morpholog0.86465194
91MP0002138_abnormal_hepatobiliary_system0.82633831
92MP0003943_abnormal_hepatobiliary_system0.80204099
93MP0005076_abnormal_cell_differentiation0.79128786
94MP0000313_abnormal_cell_death0.79055537
95MP0004484_altered_response_of0.78551488
96MP0002998_abnormal_bone_remodeling0.78273383
97MP0002933_joint_inflammation0.76391583
98MP0005621_abnormal_cell_physiology0.74703192
99MP0006054_spinal_hemorrhage0.72760875
100MP0005390_skeleton_phenotype0.69792510
101MP0005166_decreased_susceptibility_to0.68737484
102MP0009765_abnormal_xenobiotic_induced0.67844028
103MP0003828_pulmonary_edema0.67506173
104MP0003221_abnormal_cardiomyocyte_apopto0.67447074
105MP0000350_abnormal_cell_proliferation0.67313371
106MP0010352_gastrointestinal_tract_polyps0.67222917
107MP0008260_abnormal_autophagy0.66534739
108MP0001348_abnormal_lacrimal_gland0.66232942
109MP0000249_abnormal_blood_vessel0.66142175
110MP0001186_pigmentation_phenotype0.65676910
111MP0000604_amyloidosis0.65398773
112MP0003795_abnormal_bone_structure0.63368253
113MP0000681_abnormal_thyroid_gland0.61512892
114MP0005384_cellular_phenotype0.61424325
115MP0002277_abnormal_respiratory_mucosa0.59384791
116MP0009115_abnormal_fat_cell0.58710570
117MP0001851_eye_inflammation0.58332991
118MP0001663_abnormal_digestive_system0.58211038
119MP0003075_altered_response_to0.58041901
120MP0002332_abnormal_exercise_endurance0.57114558
121MP0003786_premature_aging0.56079778
122MP0001944_abnormal_pancreas_morphology0.55999420
123MP0008877_abnormal_DNA_methylation0.55774518
124MP0002254_reproductive_system_inflammat0.55221112
125MP0005376_homeostasis/metabolism_phenot0.53290026
126MP0003252_abnormal_bile_duct0.53141293
127MP0002133_abnormal_respiratory_system0.48507414
128MP0005388_respiratory_system_phenotype0.48507414
129MP0003091_abnormal_cell_migration0.47322087
130MP0008873_increased_physiological_sensi0.47245636

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)6.05350377
2Abnormality of T cell number (HP:0011839)5.69713781
3Stomatitis (HP:0010280)5.24360321
4Recurrent abscess formation (HP:0002722)5.06157899
5Recurrent bacterial skin infections (HP:0005406)4.78239715
6Myositis (HP:0100614)4.34741314
7Elevated erythrocyte sedimentation rate (HP:0003565)4.12717518
8Thrombocytosis (HP:0001894)4.10348898
9Gastrointestinal infarctions (HP:0005244)3.93802564
10IgM deficiency (HP:0002850)3.65565672
11Recurrent fungal infections (HP:0002841)3.62187755
12Eczematoid dermatitis (HP:0000976)3.60400676
13Recurrent viral infections (HP:0004429)3.54349132
14Chronic otitis media (HP:0000389)3.49802935
15Recurrent gram-negative bacterial infections (HP:0005420)3.45080254
16Severe combined immunodeficiency (HP:0004430)3.38400949
17Abnormal delayed hypersensitivity skin test (HP:0002963)3.33485263
18Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.29892499
19Acute myeloid leukemia (HP:0004808)3.24627700
20Autoimmune hemolytic anemia (HP:0001890)3.14363355
21Papilledema (HP:0001085)3.03197106
22Retrobulbar optic neuritis (HP:0100654)3.02953527
23Optic neuritis (HP:0100653)3.02953527
24Mediastinal lymphadenopathy (HP:0100721)3.01515083
25Abnormality of the fingertips (HP:0001211)2.98739424
26Recurrent cutaneous fungal infections (HP:0011370)2.95475432
27Chronic mucocutaneous candidiasis (HP:0002728)2.95475432
28Pustule (HP:0200039)2.94948616
29Recurrent skin infections (HP:0001581)2.93260379
30Panhypogammaglobulinemia (HP:0003139)2.93250991
31Chronic obstructive pulmonary disease (HP:0006510)2.90834493
32Obstructive lung disease (HP:0006536)2.90834493
33Orchitis (HP:0100796)2.86494068
34Abnormality of T cell physiology (HP:0011840)2.81176519
35Meningitis (HP:0001287)2.80085069
36B lymphocytopenia (HP:0010976)2.79261213
37Abnormality of B cell number (HP:0010975)2.79261213
38Gingival bleeding (HP:0000225)2.78151513
39Entropion (HP:0000621)2.77987238
40Increased IgM level (HP:0003496)2.72531435
41Vasculitis (HP:0002633)2.71190032
42Colitis (HP:0002583)2.70847649
43IgG deficiency (HP:0004315)2.68722929
44Basal ganglia calcification (HP:0002135)2.66871424
45Pulmonary infiltrates (HP:0002113)2.66547899
46Eosinophilia (HP:0001880)2.65528260
47Urticaria (HP:0001025)2.62569797
48Pulmonary embolism (HP:0002204)2.62333213
49Recurrent bronchitis (HP:0002837)2.61029815
50Chronic diarrhea (HP:0002028)2.58891791
51Anorexia (HP:0002039)2.58866522
52Acute lymphatic leukemia (HP:0006721)2.57134785
53Stomach cancer (HP:0012126)2.57031000
54Combined immunodeficiency (HP:0005387)2.56452738
55Prolonged bleeding time (HP:0003010)2.49723495
56Abnormality of the prostate (HP:0008775)2.44901416
57Lymphopenia (HP:0001888)2.44752226
58Syringomyelia (HP:0003396)2.41977355
59Spinal cord lesions (HP:0100561)2.41977355
60Petechiae (HP:0000967)2.41550937
61Epistaxis (HP:0000421)2.40879956
62Abnormality of macrophages (HP:0004311)2.38995634
63Spondylolisthesis (HP:0003302)2.37566625
64Gangrene (HP:0100758)2.37363550
65Viral hepatitis (HP:0006562)2.35499244
66Chest pain (HP:0100749)2.35395942
67Dysostosis multiplex (HP:0000943)2.34705265
68Abnormality of cells of the lymphoid lineage (HP:0012140)2.33494202
69Abnormality of T cells (HP:0002843)2.32088519
70Granulocytopenia (HP:0001913)2.30538750
71Encephalitis (HP:0002383)2.29406713
72Hypochromic anemia (HP:0001931)2.28866268
73Periodontitis (HP:0000704)2.28440762
74Gingivitis (HP:0000230)2.27131360
75Lymphoma (HP:0002665)2.25284537
76Hypochromic microcytic anemia (HP:0004840)2.24834766
77Thyroiditis (HP:0100646)2.24066793
78Agammaglobulinemia (HP:0004432)2.22751512
79Abnormality of eosinophils (HP:0001879)2.21110635
80Autoimmune thrombocytopenia (HP:0001973)2.19247605
81Cellulitis (HP:0100658)2.18935875
82Interstitial pulmonary disease (HP:0006530)2.18832527
83Subacute progressive viral hepatitis (HP:0006572)2.17926762
84Episodic fever (HP:0001954)2.15535301
85Neoplasm of the tracheobronchial system (HP:0100552)2.15516602
86Degeneration of anterior horn cells (HP:0002398)2.14886251
87Abnormality of the anterior horn cell (HP:0006802)2.14886251
88Joint swelling (HP:0001386)2.14668287
89Leukocytosis (HP:0001974)2.13446518
90Myelodysplasia (HP:0002863)2.12552720
91Recurrent pneumonia (HP:0006532)2.10646707
92Sepsis (HP:0100806)2.10223888
93Hemoptysis (HP:0002105)2.09731016
94Papilloma (HP:0012740)2.08198211
95Verrucae (HP:0200043)2.08198211
96Acute hepatic failure (HP:0006554)2.07496454
97Inflammation of the large intestine (HP:0002037)2.06250677
98Arterial thrombosis (HP:0004420)2.05405913
99Hypoplasia of the thymus (HP:0000778)2.04249258
100Bronchitis (HP:0012387)2.03948641
101Slow saccadic eye movements (HP:0000514)2.03819322
102Glomerulopathy (HP:0100820)2.03618581
103Increased IgE level (HP:0003212)2.03159891
104IgA deficiency (HP:0002720)2.02933093
105Keratitis (HP:0000491)2.02071969
106Peritonitis (HP:0002586)2.01516578
107Poikiloderma (HP:0001029)2.00732123
108Hemiplegia (HP:0002301)2.00722605
109Emphysema (HP:0002097)2.00187617
110Alveolar cell carcinoma (HP:0006519)1.97545563
111Gastrointestinal stroma tumor (HP:0100723)1.96982976
112Hypergammaglobulinemia (HP:0010702)1.96218246
113Abnormality of the thoracic spine (HP:0100711)1.96095234
114Restrictive lung disease (HP:0002091)1.94343288
115Microcytic anemia (HP:0001935)1.94199559
116Keratoconjunctivitis sicca (HP:0001097)1.94024431
117Prominent nose (HP:0000448)1.93815943
118Recurrent lower respiratory tract infections (HP:0002783)1.93677175
119Hypoproteinemia (HP:0003075)1.93502208
120Abnormality of the endocardium (HP:0004306)1.93255945
121Gastrointestinal inflammation (HP:0004386)1.92046568
122Osteomyelitis (HP:0002754)1.91883291
123Aplastic anemia (HP:0001915)1.89681999
124Leukopenia (HP:0001882)1.88365398
125Albinism (HP:0001022)1.87774019
126Keratoconjunctivitis (HP:0001096)1.87522340
127Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.87379199
128Abnormal protein N-linked glycosylation (HP:0012347)1.87379199
129Abnormal protein glycosylation (HP:0012346)1.87379199
130Abnormal glycosylation (HP:0012345)1.87379199
131Spontaneous hematomas (HP:0007420)1.87187329
132Fatigue (HP:0012378)1.86863045
133Type I transferrin isoform profile (HP:0003642)1.86816128
134Osteolytic defects of the hand bones (HP:0009699)1.83919490
135Osteolytic defects of the phalanges of the hand (HP:0009771)1.83919490
136Disinhibition (HP:0000734)1.83630060
137Abnormality of glycolipid metabolism (HP:0010969)1.83361101
138Abnormality of liposaccharide metabolism (HP:0010968)1.83361101
139Abnormality of glycosphingolipid metabolism (HP:0004343)1.83361101
140Abnormality of the pleura (HP:0002103)1.81911735
141Thoracic kyphosis (HP:0002942)1.81749809
142Increased neuronal autofluorescent lipopigment (HP:0002074)1.81268121
143Mucopolysacchariduria (HP:0008155)1.80372033

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK43.97661329
2KIT3.16043475
3TEC2.98453223
4FLT32.98400040
5MAP4K12.84214166
6TAOK32.61558454
7MAP3K142.58262845
8GRK62.49079219
9IRAK32.23802456
10TXK2.22979139
11CSF1R2.15834107
12BRSK22.13172949
13TYK22.11759537
14BTK2.09585456
15PIM22.04356797
16IKBKB1.86433266
17JAK31.85169861
18PRPF4B1.83859848
19RIPK41.83369424
20ZAP701.78263919
21TBK11.75553869
22TSSK61.68775519
23SYK1.61072441
24ACVR1B1.61028475
25STK161.52725919
26FRK1.50253191
27IKBKE1.44593119
28JAK11.41784733
29CHUK1.40728061
30FGR1.37692593
31TNK21.37556838
32ITK1.36386281
33CAMKK21.33172836
34MAP3K131.24698343
35STK241.22056951
36WEE11.21012057
37ATR1.18793527
38PASK1.15106848
39PIM11.14017513
40BLK1.13674292
41MAP2K31.11120686
42BMPR1B1.11027530
43ERBB31.08606731
44HIPK21.04997144
45RPS6KA41.04576300
46CCNB11.04024413
47NEK21.00615047
48NUAK10.96598567
49EIF2AK20.96369252
50FES0.95108619
51SIK20.94831402
52MAP3K60.93475041
53FGFR40.92602766
54BUB10.91084625
55SCYL20.90905821
56MAP3K30.90467051
57EIF2AK30.90106946
58CLK10.90066905
59STK100.89079430
60LCK0.88944613
61LYN0.88492625
62HCK0.87926966
63PRKCQ0.85507514
64MKNK20.82893715
65MAP3K20.82376292
66PDK10.81984008
67BMPR20.81722824
68MAPK150.80865481
69MAP3K120.79650763
70MAP3K10.78654647
71FGFR30.78051779
72RPS6KA20.74525507
73BRSK10.71813670
74PTK2B0.70896872
75SGK30.70584758
76TAOK10.68567107
77TGFBR10.67277675
78EPHA30.67264706
79GRK70.67222441
80PLK30.66636065
81RPS6KA60.66530436
82CAMKK10.66326074
83EEF2K0.64987416
84DYRK30.64982099
85MAPK70.64433183
86MAP3K50.64357090
87SRPK10.64110125
88VRK10.63440017
89ZAK0.63346571
90NLK0.63008293
91MARK20.62961062
92TGFBR20.59517675
93MATK0.58868292
94PLK40.58798678
95FYN0.58707787
96IRAK20.58282614
97CDK40.58059635
98STK110.56498063
99IRAK10.56357967
100ERN10.55822685
101RPS6KC10.55239032
102RPS6KL10.55239032
103LRRK20.54459268
104MKNK10.53841803
105MAP2K60.53580689
106RIPK10.52853214
107SIK30.52694731
108KSR20.51868411
109EPHB10.51717137
110TRPM70.51518645
111YES10.51506013
112BRD40.51076408
113CHEK20.49672772
114MAPK120.48534437
115RET0.48086233
116PDGFRB0.46699286
117CSNK1A1L0.45748694
118PIK3CA0.45744501
119MAP3K70.45676000
120MARK30.45186650
121PIK3CG0.44847947
122STK380.44656093
123STK30.44387293
124MAP3K110.43555804
125MAPK40.42540904
126SGK20.42331168
127WNK10.41728053
128MAPKAPK20.41621352
129MELK0.41468709
130CDK60.41345797
131RPS6KB10.41151729
132CSK0.40309414
133EIF2AK10.40194855
134GRK50.40089476
135KSR10.39935114
136CDK80.39226290
137JAK20.38505159
138NEK60.38389401
139SGK2230.38320987
140SGK4940.38320987
141EGFR0.37564350
142CDC70.37544749
143CAMK40.37224714
144STK40.34658846
145RAF10.34639924
146DYRK1A0.33611115
147PDPK10.33157923

Predicted pathways (KEGG)

RankGene SetZ-score
1Autoimmune thyroid disease_Homo sapiens_hsa053202.36821816
2NF-kappa B signaling pathway_Homo sapiens_hsa040642.15914558
3Leishmaniasis_Homo sapiens_hsa051402.10627009
4Staphylococcus aureus infection_Homo sapiens_hsa051502.08127283
5Antigen processing and presentation_Homo sapiens_hsa046122.04434302
6Primary immunodeficiency_Homo sapiens_hsa053402.01294172
7DNA replication_Homo sapiens_hsa030301.89171630
8Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.88195510
9Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.75689266
10Intestinal immune network for IgA production_Homo sapiens_hsa046721.72296638
11Osteoclast differentiation_Homo sapiens_hsa043801.72254072
12NOD-like receptor signaling pathway_Homo sapiens_hsa046211.71402637
13Measles_Homo sapiens_hsa051621.70544664
14Non-homologous end-joining_Homo sapiens_hsa034501.69946562
15Base excision repair_Homo sapiens_hsa034101.67521411
16B cell receptor signaling pathway_Homo sapiens_hsa046621.62390458
17Herpes simplex infection_Homo sapiens_hsa051681.59941688
18RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.54393320
19Toll-like receptor signaling pathway_Homo sapiens_hsa046201.53813953
20Homologous recombination_Homo sapiens_hsa034401.53369145
21Protein export_Homo sapiens_hsa030601.47147759
22Glycosaminoglycan degradation_Homo sapiens_hsa005311.40495521
23Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.36898770
24Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.35489084
25Mismatch repair_Homo sapiens_hsa034301.34339410
26Influenza A_Homo sapiens_hsa051641.24219261
27Cell cycle_Homo sapiens_hsa041101.22236020
28Legionellosis_Homo sapiens_hsa051341.21733842
29Hematopoietic cell lineage_Homo sapiens_hsa046401.20628166
30TNF signaling pathway_Homo sapiens_hsa046681.19398877
31Toxoplasmosis_Homo sapiens_hsa051451.18554194
32Epstein-Barr virus infection_Homo sapiens_hsa051691.18000959
33Tuberculosis_Homo sapiens_hsa051521.17725462
34Jak-STAT signaling pathway_Homo sapiens_hsa046301.17633246
35Other glycan degradation_Homo sapiens_hsa005111.16875002
36p53 signaling pathway_Homo sapiens_hsa041151.14158204
37Apoptosis_Homo sapiens_hsa042101.14033423
38Lysosome_Homo sapiens_hsa041421.13254594
39Pertussis_Homo sapiens_hsa051331.12133188
40Shigellosis_Homo sapiens_hsa051311.10756607
41N-Glycan biosynthesis_Homo sapiens_hsa005101.10101737
42Transcriptional misregulation in cancer_Homo sapiens_hsa052021.08816788
43Hepatitis B_Homo sapiens_hsa051611.07506534
44Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.06283978
45Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.05386007
46Fanconi anemia pathway_Homo sapiens_hsa034601.05088777
47Allograft rejection_Homo sapiens_hsa053301.04356072
48Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.01709870
49Chemokine signaling pathway_Homo sapiens_hsa040621.01409036
50Dorso-ventral axis formation_Homo sapiens_hsa043200.99588052
51RNA polymerase_Homo sapiens_hsa030200.96101999
52Acute myeloid leukemia_Homo sapiens_hsa052210.95575078
53Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.95556204
54Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.91896581
55Chronic myeloid leukemia_Homo sapiens_hsa052200.90804118
56Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.90377004
57Phosphatidylinositol signaling system_Homo sapiens_hsa040700.90122665
58T cell receptor signaling pathway_Homo sapiens_hsa046600.88930368
59Spliceosome_Homo sapiens_hsa030400.87382719
60Regulation of autophagy_Homo sapiens_hsa041400.87345711
61Neurotrophin signaling pathway_Homo sapiens_hsa047220.86769586
62Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.86468507
63Type I diabetes mellitus_Homo sapiens_hsa049400.84176632
64Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.83173792
65RNA degradation_Homo sapiens_hsa030180.82404738
66Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.81936900
67RNA transport_Homo sapiens_hsa030130.80144371
68HTLV-I infection_Homo sapiens_hsa051660.79867604
69Nucleotide excision repair_Homo sapiens_hsa034200.79833348
70Carbohydrate digestion and absorption_Homo sapiens_hsa049730.78424407
71Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.77430497
72Salmonella infection_Homo sapiens_hsa051320.77253813
73Viral myocarditis_Homo sapiens_hsa054160.75091045
74VEGF signaling pathway_Homo sapiens_hsa043700.74677134
75Graft-versus-host disease_Homo sapiens_hsa053320.74050420
76Renal cell carcinoma_Homo sapiens_hsa052110.73831927
77Viral carcinogenesis_Homo sapiens_hsa052030.73816639
78Pancreatic cancer_Homo sapiens_hsa052120.72511811
79Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.71057221
80Small cell lung cancer_Homo sapiens_hsa052220.70849184
81Sphingolipid signaling pathway_Homo sapiens_hsa040710.70634593
82Pyrimidine metabolism_Homo sapiens_hsa002400.70299863
83Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.70113069
84Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.69046562
85Malaria_Homo sapiens_hsa051440.68387304
86Maturity onset diabetes of the young_Homo sapiens_hsa049500.68048942
87Platelet activation_Homo sapiens_hsa046110.67701645
88Leukocyte transendothelial migration_Homo sapiens_hsa046700.67450513
89Asthma_Homo sapiens_hsa053100.66262009
90Phagosome_Homo sapiens_hsa041450.65800578
91Prolactin signaling pathway_Homo sapiens_hsa049170.65075768
92Proteasome_Homo sapiens_hsa030500.64623765
93Hepatitis C_Homo sapiens_hsa051600.63459043
94mTOR signaling pathway_Homo sapiens_hsa041500.63363549
95Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.63046261
96Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.62553660
97Choline metabolism in cancer_Homo sapiens_hsa052310.61886667
98Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.61415723
99Endometrial cancer_Homo sapiens_hsa052130.59718474
100SNARE interactions in vesicular transport_Homo sapiens_hsa041300.58599179
101AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.58165360
102Type II diabetes mellitus_Homo sapiens_hsa049300.56532054
103Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.56266330
104Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.55509087
105Rheumatoid arthritis_Homo sapiens_hsa053230.54840489
106Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.54098741
107Insulin resistance_Homo sapiens_hsa049310.52445442
108Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.52044039
109FoxO signaling pathway_Homo sapiens_hsa040680.51804395
110Phospholipase D signaling pathway_Homo sapiens_hsa040720.50697851
111African trypanosomiasis_Homo sapiens_hsa051430.49970834
112Basal transcription factors_Homo sapiens_hsa030220.49656851
113Non-small cell lung cancer_Homo sapiens_hsa052230.49294407
114Colorectal cancer_Homo sapiens_hsa052100.48898728
115MAPK signaling pathway_Homo sapiens_hsa040100.47265143
116Adipocytokine signaling pathway_Homo sapiens_hsa049200.47198503
117Endocytosis_Homo sapiens_hsa041440.46023463
118Renin-angiotensin system_Homo sapiens_hsa046140.45864983
119Inositol phosphate metabolism_Homo sapiens_hsa005620.45631643
120Prostate cancer_Homo sapiens_hsa052150.43647812
121GnRH signaling pathway_Homo sapiens_hsa049120.42427324
122Glycerophospholipid metabolism_Homo sapiens_hsa005640.38995927
123ErbB signaling pathway_Homo sapiens_hsa040120.37421878
124Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.37364943
125HIF-1 signaling pathway_Homo sapiens_hsa040660.35017644
126Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.34603491
127Long-term potentiation_Homo sapiens_hsa047200.34488850
128Longevity regulating pathway - mammal_Homo sapiens_hsa042110.34313473
129Glioma_Homo sapiens_hsa052140.33890047
130Ras signaling pathway_Homo sapiens_hsa040140.32238819
131Cholinergic synapse_Homo sapiens_hsa047250.31709940
132Estrogen signaling pathway_Homo sapiens_hsa049150.30868985
133Systemic lupus erythematosus_Homo sapiens_hsa053220.26077030
134Circadian rhythm_Homo sapiens_hsa047100.24606559

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