PAQR9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.15929795
2L-phenylalanine catabolic process (GO:0006559)7.15929795
3L-phenylalanine metabolic process (GO:0006558)6.83682113
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)6.83682113
5aromatic amino acid family catabolic process (GO:0009074)6.40223568
6triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.12332435
7protein-lipid complex assembly (GO:0065005)6.03462904
8alpha-linolenic acid metabolic process (GO:0036109)5.81216246
9indole-containing compound catabolic process (GO:0042436)5.75456950
10indolalkylamine catabolic process (GO:0046218)5.75456950
11tryptophan catabolic process (GO:0006569)5.75456950
12kynurenine metabolic process (GO:0070189)5.74398811
13intestinal cholesterol absorption (GO:0030299)5.72274501
14bile acid biosynthetic process (GO:0006699)5.68795466
15glyoxylate metabolic process (GO:0046487)5.56816948
16tryptophan metabolic process (GO:0006568)5.40768127
17plasma lipoprotein particle organization (GO:0071827)5.35530497
18protoporphyrinogen IX metabolic process (GO:0046501)5.29910820
19urea metabolic process (GO:0019627)5.28256368
20urea cycle (GO:0000050)5.28256368
21negative regulation of fibrinolysis (GO:0051918)5.23381152
22high-density lipoprotein particle remodeling (GO:0034375)5.23210274
23cysteine metabolic process (GO:0006534)5.19182891
24protein-lipid complex subunit organization (GO:0071825)5.05818608
25regulation of fibrinolysis (GO:0051917)5.05501600
26regulation of plasminogen activation (GO:0010755)5.04228909
27sulfur amino acid catabolic process (GO:0000098)4.99788083
28fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.96497517
29regulation of protein activation cascade (GO:2000257)4.94812270
30complement activation, alternative pathway (GO:0006957)4.93837774
31protein carboxylation (GO:0018214)4.93438361
32peptidyl-glutamic acid carboxylation (GO:0017187)4.93438361
33nitrogen cycle metabolic process (GO:0071941)4.86388837
34bile acid metabolic process (GO:0008206)4.85769595
35serine family amino acid catabolic process (GO:0009071)4.84776961
36lysine catabolic process (GO:0006554)4.79038574
37lysine metabolic process (GO:0006553)4.79038574
38regulation of triglyceride catabolic process (GO:0010896)4.73946521
39cellular ketone body metabolic process (GO:0046950)4.71872502
40reverse cholesterol transport (GO:0043691)4.63198001
41aromatic amino acid family metabolic process (GO:0009072)4.62315173
42regulation of complement activation (GO:0030449)4.59166238
43amino-acid betaine metabolic process (GO:0006577)4.56767009
44protein-lipid complex remodeling (GO:0034368)4.54869465
45macromolecular complex remodeling (GO:0034367)4.54869465
46plasma lipoprotein particle remodeling (GO:0034369)4.54869465
47regulation of cholesterol esterification (GO:0010872)4.53491286
48triglyceride homeostasis (GO:0070328)4.50839969
49acylglycerol homeostasis (GO:0055090)4.50839969
50tyrosine metabolic process (GO:0006570)4.48561052
51alpha-amino acid catabolic process (GO:1901606)4.46435398
52homocysteine metabolic process (GO:0050667)4.42470817
53protoporphyrinogen IX biosynthetic process (GO:0006782)4.33379341
54glutamate metabolic process (GO:0006536)4.32824175
55phospholipid efflux (GO:0033700)4.31311678
56positive regulation of blood coagulation (GO:0030194)4.28064142
57positive regulation of hemostasis (GO:1900048)4.28064142
58coenzyme catabolic process (GO:0009109)4.25792351
59dicarboxylic acid biosynthetic process (GO:0043650)4.25353678
60plasma lipoprotein particle clearance (GO:0034381)4.25031580
61negative regulation of sterol transport (GO:0032372)4.23863042
62negative regulation of cholesterol transport (GO:0032375)4.23863042
63cellular amino acid catabolic process (GO:0009063)4.14266443
64hemoglobin metabolic process (GO:0020027)4.13953931
65ketone body metabolic process (GO:1902224)4.07841893
66indolalkylamine metabolic process (GO:0006586)4.05712830
67bile acid and bile salt transport (GO:0015721)4.03798156
68cholesterol efflux (GO:0033344)4.01218266
69negative regulation of hemostasis (GO:1900047)4.00324684
70negative regulation of blood coagulation (GO:0030195)4.00324684
71cellular modified amino acid catabolic process (GO:0042219)3.97301346
72glycine metabolic process (GO:0006544)3.94542001
73regulation of apoptotic cell clearance (GO:2000425)3.93894988
74amine catabolic process (GO:0009310)3.92924080
75cellular biogenic amine catabolic process (GO:0042402)3.92924080
76peptidyl-glutamic acid modification (GO:0018200)3.91712480
77short-chain fatty acid metabolic process (GO:0046459)3.90720566
78proline metabolic process (GO:0006560)3.89688457
79acetyl-CoA metabolic process (GO:0006084)3.88807304
80imidazole-containing compound metabolic process (GO:0052803)3.88766664
81porphyrin-containing compound metabolic process (GO:0006778)3.88384164
82ethanol oxidation (GO:0006069)3.88006934
83serine family amino acid metabolic process (GO:0009069)3.86310626
84positive regulation of coagulation (GO:0050820)3.86094774
85positive regulation of lipid catabolic process (GO:0050996)3.85960817
86benzene-containing compound metabolic process (GO:0042537)3.85218792
87drug catabolic process (GO:0042737)3.84526620
88positive regulation of fatty acid biosynthetic process (GO:0045723)3.79178075
89plasma lipoprotein particle assembly (GO:0034377)3.77450266
90phospholipid homeostasis (GO:0055091)3.76749266
91cellular glucuronidation (GO:0052695)3.76748983
92low-density lipoprotein particle remodeling (GO:0034374)3.74929371
93porphyrin-containing compound biosynthetic process (GO:0006779)3.73844423
94arginine metabolic process (GO:0006525)3.71574020
95organic acid catabolic process (GO:0016054)3.71204555
96carboxylic acid catabolic process (GO:0046395)3.71204555
97aspartate family amino acid catabolic process (GO:0009068)3.66885892
98fibrinolysis (GO:0042730)3.66749956
99negative regulation of lipase activity (GO:0060192)3.65237451
100positive regulation of fatty acid beta-oxidation (GO:0032000)3.65009195
101fatty acid beta-oxidation (GO:0006635)3.63308669
102negative regulation of fatty acid biosynthetic process (GO:0045717)3.61073573
103monocarboxylic acid catabolic process (GO:0072329)3.59944756
1042-oxoglutarate metabolic process (GO:0006103)3.59354675
105fatty acid oxidation (GO:0019395)3.59123847
106cofactor catabolic process (GO:0051187)3.58871606
107negative regulation of coagulation (GO:0050819)3.58236228
108blood coagulation, intrinsic pathway (GO:0007597)3.57732077
109regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)3.56231308
110positive regulation of triglyceride lipase activity (GO:0061365)3.55890549
111positive regulation of lipoprotein lipase activity (GO:0051006)3.55890549
112regulation of cholesterol homeostasis (GO:2000188)3.54679383
113regulation of bile acid biosynthetic process (GO:0070857)3.54317760
114serine family amino acid biosynthetic process (GO:0009070)3.52761598
115lipid oxidation (GO:0034440)3.52470293
116cholesterol homeostasis (GO:0042632)3.51987366
117regulation of fatty acid biosynthetic process (GO:0042304)3.51910114
118very-low-density lipoprotein particle assembly (GO:0034379)3.51899271
119exogenous drug catabolic process (GO:0042738)3.50883137
120fatty acid catabolic process (GO:0009062)3.50688532
121cytolysis (GO:0019835)3.48576020
122aldehyde catabolic process (GO:0046185)3.47331569
123sterol homeostasis (GO:0055092)3.46871546
124phosphatidylethanolamine biosynthetic process (GO:0006646)3.45947291
125complement activation, classical pathway (GO:0006958)3.44865434
126negative regulation of wound healing (GO:0061045)3.42101077
127epoxygenase P450 pathway (GO:0019373)3.40754832
128phosphatidylethanolamine metabolic process (GO:0046337)3.37575665
129cholesterol transport (GO:0030301)3.36560693
130sterol transport (GO:0015918)3.36560693
131acute-phase response (GO:0006953)3.36524311
132protein activation cascade (GO:0072376)3.35190005
133lipoprotein metabolic process (GO:0042157)3.33851234
134embryonic retina morphogenesis in camera-type eye (GO:0060059)3.30654614
135response to mercury ion (GO:0046689)3.28938228
136intestinal absorption (GO:0050892)3.25554266
137regulation of cell-cell adhesion mediated by cadherin (GO:2000047)3.25430788
138tetrapyrrole biosynthetic process (GO:0033014)3.25261137
139regulation of cholesterol biosynthetic process (GO:0045540)3.24254790
140heme metabolic process (GO:0042168)3.23544723
141positive regulation of steroid metabolic process (GO:0045940)3.18905910
142response to methylmercury (GO:0051597)3.16455552
143oxygen transport (GO:0015671)3.15336622
144polyketide metabolic process (GO:0030638)3.12176696
145doxorubicin metabolic process (GO:0044598)3.12176696
146daunorubicin metabolic process (GO:0044597)3.12176696

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse7.60152532
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse6.43843031
3* LXR_22158963_ChIP-Seq_LIVER_Mouse5.95793114
4EGR1_23403033_ChIP-Seq_LIVER_Mouse5.94478732
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.97569512
6FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.95512758
7CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.16540734
8* NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.86479605
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.19946928
10CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.29555026
11TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.00686571
12ESR1_17901129_ChIP-ChIP_LIVER_Mouse10.7776724
13TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.98583003
14HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.70102141
15FOXA2_19822575_ChIP-Seq_HepG2_Human1.67412874
16TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.66678597
17KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.63515453
18HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.58339397
19HTT_18923047_ChIP-ChIP_STHdh_Human1.51543135
20* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.39432227
21THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.38961800
22GATA1_22025678_ChIP-Seq_K562_Human1.37458771
23HNF4A_19822575_ChIP-Seq_HepG2_Human1.34094506
24PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.33827538
25CLOCK_20551151_ChIP-Seq_293T_Human1.30835981
26* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.26268783
27ELF1_20517297_ChIP-Seq_JURKAT_Human1.23602605
28E2F7_22180533_ChIP-Seq_HELA_Human1.22385752
29NFIB_24661679_ChIP-Seq_LUNG_Mouse1.18599738
30TCF4_18268006_ChIP-ChIP_LS174T_Human1.17383239
31SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.13397266
32ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.12806073
33GATA3_20176728_ChIP-ChIP_TSCs_Mouse1.12685720
34RAC3_21632823_ChIP-Seq_H3396_Human1.10895473
35NANOG_21062744_ChIP-ChIP_HESCs_Human1.07825068
36GATA6_25053715_ChIP-Seq_YYC3_Human1.04916140
37P68_20966046_ChIP-Seq_HELA_Human1.04823732
38RBPJ_22232070_ChIP-Seq_NCS_Mouse1.04779063
39NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.03758547
40TAF15_26573619_Chip-Seq_HEK293_Human1.03517645
41SMC4_20622854_ChIP-Seq_HELA_Human1.03234688
42RXRA_24833708_ChIP-Seq_LIVER_Mouse0.99945140
43BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.98828073
44EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.97686234
45ZNF263_19887448_ChIP-Seq_K562_Human0.97203783
46PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.97140754
47EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.94549468
48* PHF8_20622854_ChIP-Seq_HELA_Human0.91353748
49YY1_22570637_ChIP-Seq_MALME-3M_Human0.91254550
50ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.90203407
51MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.89664976
52SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88035679
53GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85540224
54ESR1_15608294_ChIP-ChIP_MCF-7_Human0.85365529
55SOX11_22085726_ChIP-Seq_ESNs_Mouse0.84422551
56STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.83623320
57AUTS2_25519132_ChIP-Seq_293T-REX_Human0.82722071
58GBX2_23144817_ChIP-Seq_PC3_Human0.82391581
59* BCOR_27268052_Chip-Seq_Bcells_Human0.81790402
60GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.80419082
61STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.80232773
62ERG_21242973_ChIP-ChIP_JURKAT_Human0.80173875
63MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.79639778
64OCT4_20526341_ChIP-Seq_ESCs_Human0.78746781
65ERA_21632823_ChIP-Seq_H3396_Human0.78156982
66GATA1_22383799_ChIP-Seq_G1ME_Mouse0.77797824
67* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.77144898
68SOX2_22085726_ChIP-Seq_NPCs_Mouse0.76391666
69CBX2_22325352_ChIP-Seq_293T-Rex_Human0.75881692
70KDM2B_26808549_Chip-Seq_K562_Human0.74872295
71FOXO3_23340844_ChIP-Seq_DLD1_Human0.74273531
72NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.74164317
73NRF2_20460467_ChIP-Seq_MEFs_Mouse0.74164317
74SPI1_20517297_ChIP-Seq_HL60_Human0.73480949
75BCAT_22108803_ChIP-Seq_LS180_Human0.73090828
76SOX2_21211035_ChIP-Seq_LN229_Human0.72507537
77AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.71620309
78* SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.70826606
79ESR2_21235772_ChIP-Seq_MCF-7_Human0.70649266
80SOX2_27498859_Chip-Seq_STOMACH_Mouse0.69415816
81NANOG_20526341_ChIP-Seq_ESCs_Human0.69094767
82STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.68624164
83BCL6_27268052_Chip-Seq_Bcells_Human0.68015051
84CSB_26484114_Chip-Seq_FIBROBLAST_Human0.67794301
85TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.67699074
86* FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.67040714
87NCOR1_26117541_ChIP-Seq_K562_Human0.66536409
88ESR1_20079471_ChIP-ChIP_T-47D_Human0.66321239
89PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.65419593
90E2F1_20622854_ChIP-Seq_HELA_Human0.65214041
91POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.65010033
92TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.65010033
93RAD21_21589869_ChIP-Seq_MESCs_Mouse0.63952001
94* SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.63767190
95NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.63712871
96PIAS1_25552417_ChIP-Seq_VCAP_Human0.62272635
97POU5F1_16518401_ChIP-PET_MESCs_Mouse0.62023221
98* OCT4_19829295_ChIP-Seq_ESCs_Human0.61939100
99GF1_26923725_Chip-Seq_HPCs_Mouse0.61862631
100EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.61823000
101RARG_19884340_ChIP-ChIP_MEFs_Mouse0.61149961
102IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.61049494
103PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.60814463
104* SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.60327643
105GATA1_19941826_ChIP-Seq_K562_Human0.60300099
106RARA_24833708_ChIP-Seq_LIVER_Mouse0.59921666
107AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.59801400
108LXR_22292898_ChIP-Seq_THP-1_Human0.58208325
109SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.57509329
110MYC_19915707_ChIP-ChIP_AK7_Human0.56838259
111BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.56645068
112CBP_21632823_ChIP-Seq_H3396_Human0.56309223
113ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.56155222
114REST_21632747_ChIP-Seq_MESCs_Mouse0.55814249
115* MTF2_20144788_ChIP-Seq_MESCs_Mouse0.55469711
116Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.54660534
117* REST_18959480_ChIP-ChIP_MESCs_Mouse0.54324248
118GATA4_25053715_ChIP-Seq_YYC3_Human0.54081546
119* GATA1_19941827_ChIP-Seq_MEL_Mouse0.53267485
120KAP1_22055183_ChIP-Seq_ESCs_Mouse0.52706964
121BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.52610816
122CTCF_27219007_Chip-Seq_Bcells_Human0.52566632
123DROSHA_22980978_ChIP-Seq_HELA_Human0.52426176
124EGR1_19032775_ChIP-ChIP_M12_Human0.52054046
125* SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.51989088
126DNAJC2_21179169_ChIP-ChIP_NT2_Human0.51844023
127NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.51812572
128PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.51585263
129SMAD4_21741376_ChIP-Seq_EPCs_Human0.49527482
130* SMAD4_21741376_ChIP-Seq_HESCs_Human0.49032413
131MYC_27129775_Chip-Seq_CORNEA_Mouse0.48808638
132EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.48533362
133CTBP1_25329375_ChIP-Seq_LNCAP_Human0.48495630
134* ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.48171883
135FOXA1_25552417_ChIP-Seq_VCAP_Human0.48110625
136SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.47926104
137* GATA2_19941826_ChIP-Seq_K562_Human0.47804106
138STAT1_17558387_ChIP-Seq_HELA_Human0.47103774
139CBP_20019798_ChIP-Seq_JUKART_Human0.46470218
140IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.46470218
141* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.46090701
142SOX2_21211035_ChIP-Seq_LN229_Gbm0.45845985
143TAF2_19829295_ChIP-Seq_ESCs_Human0.45519856
144ESET_19884257_ChIP-Seq_ESCs_Mouse0.45424552
145P53_21459846_ChIP-Seq_SAOS-2_Human0.45237192
146CTBP2_25329375_ChIP-Seq_LNCAP_Human0.45230037
147RARB_24833708_ChIP-Seq_LIVER_Mouse0.44824844
148* CEBPB_22108803_ChIP-Seq_LS180_Human0.44388429
149PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.44184443
150CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.44099939
151NCOR_22424771_ChIP-Seq_293T_Human0.43441518
152SALL4_18804426_ChIP-ChIP_XEN_Mouse0.43136320
153FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.42812767
154CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.42801868

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.16680437
2MP0005360_urolithiasis7.24490894
3MP0005085_abnormal_gallbladder_physiolo6.27544477
4MP0005365_abnormal_bile_salt6.08504406
5MP0008875_abnormal_xenobiotic_pharmacok4.84908712
6MP0003252_abnormal_bile_duct3.81739417
7MP0003806_abnormal_nucleotide_metabolis3.75314311
8MP0010329_abnormal_lipoprotein_level3.64693641
9MP0005083_abnormal_biliary_tract3.04758976
10MP0005410_abnormal_fertilization2.96953887
11MP0009840_abnormal_foam_cell2.91499861
12MP0005332_abnormal_amino_acid2.78600531
13MP0003122_maternal_imprinting2.78529386
14MP0003195_calcinosis2.73348395
15MP0001666_abnormal_nutrient_absorption2.41414173
16MP0003191_abnormal_cellular_cholesterol2.25000728
17MP0002118_abnormal_lipid_homeostasis2.22735502
18MP0004019_abnormal_vitamin_homeostasis2.10740441
19MP0000609_abnormal_liver_physiology2.09608435
20MP0003878_abnormal_ear_physiology2.05263471
21MP0005377_hearing/vestibular/ear_phenot2.05263471
22MP0000566_synostosis1.97615159
23MP0003868_abnormal_feces_composition1.84413429
24MP0002138_abnormal_hepatobiliary_system1.82347993
25MP0005319_abnormal_enzyme/_coenzyme1.79083220
26MP0005584_abnormal_enzyme/coenzyme_acti1.64781151
27MP0001764_abnormal_homeostasis1.57429969
28MP0003172_abnormal_lysosome_physiology1.49619788
29MP0003123_paternal_imprinting1.45060191
30MP0003656_abnormal_erythrocyte_physiolo1.43805004
31MP0001915_intracranial_hemorrhage1.40163746
32MP0009697_abnormal_copulation1.39443222
33MP0002089_abnormal_postnatal_growth/wei1.38014966
34MP0003646_muscle_fatigue1.34201436
35MP0002132_abnormal_respiratory_system1.33877367
36MP0005451_abnormal_body_composition1.33136004
37MP0003698_abnormal_male_reproductive1.29963747
38MP0000604_amyloidosis1.28533866
39MP0003011_delayed_dark_adaptation1.27810080
40MP0002837_dystrophic_cardiac_calcinosis1.24373837
41MP0004130_abnormal_muscle_cell1.19964537
42MP0009643_abnormal_urine_homeostasis1.18670358
43MP0005670_abnormal_white_adipose1.11843383
44MP0002876_abnormal_thyroid_physiology1.11280276
45MP0001929_abnormal_gametogenesis1.10500221
46MP0002822_catalepsy1.09873334
47MP0003329_amyloid_beta_deposits1.08645883
48MP0005647_abnormal_sex_gland1.06754236
49MP0005535_abnormal_body_temperature1.05846280
50MP0006036_abnormal_mitochondrial_physio1.04689855
51MP0000598_abnormal_liver_morphology1.03536556
52MP0003186_abnormal_redox_activity1.02776922
53MP0005636_abnormal_mineral_homeostasis1.00264395
54MP0002078_abnormal_glucose_homeostasis0.96412377
55MP0002971_abnormal_brown_adipose0.95417291
56MP0002249_abnormal_larynx_morphology0.93155933
57MP0009764_decreased_sensitivity_to0.91201037
58MP0002161_abnormal_fertility/fecundity0.89735291
59MP0003705_abnormal_hypodermis_morpholog0.87842982
60MP0009763_increased_sensitivity_to0.86830142
61MP0009642_abnormal_blood_homeostasis0.86064579
62MP0005334_abnormal_fat_pad0.85549402
63MP0002254_reproductive_system_inflammat0.85261622
64MP0003690_abnormal_glial_cell0.83826485
65MP0000749_muscle_degeneration0.83225462
66MP0005084_abnormal_gallbladder_morpholo0.83158611
67MP0010368_abnormal_lymphatic_system0.83004402
68MP0003718_maternal_effect0.81241217
69MP0006035_abnormal_mitochondrial_morpho0.76917081
70MP0005376_homeostasis/metabolism_phenot0.75219859
71MP0005448_abnormal_energy_balance0.73164596
72MP0008469_abnormal_protein_level0.70433432
73MP0009765_abnormal_xenobiotic_induced0.68987915
74MP0001545_abnormal_hematopoietic_system0.68974861
75MP0005397_hematopoietic_system_phenotyp0.68974861
76MP0008874_decreased_physiological_sensi0.67853754
77MP0005666_abnormal_adipose_tissue0.67385583
78MP0001756_abnormal_urination0.66136122
79MP0005187_abnormal_penis_morphology0.65304705
80MP0001661_extended_life_span0.65062716
81MP0005266_abnormal_metabolism0.65043755
82MP0003121_genomic_imprinting0.64576703
83MP0004036_abnormal_muscle_relaxation0.61568699
84MP0010630_abnormal_cardiac_muscle0.60853689
85MP0003567_abnormal_fetal_cardiomyocyte0.60512180
86MP0003890_abnormal_embryonic-extraembry0.60451706
87MP0008872_abnormal_physiological_respon0.58063412
88MP0003632_abnormal_nervous_system0.57998239
89MP0001529_abnormal_vocalization0.57226200
90MP0008775_abnormal_heart_ventricle0.56434256
91MP0003953_abnormal_hormone_level0.55969683
92MP0000003_abnormal_adipose_tissue0.55805270
93MP0003699_abnormal_female_reproductive0.55774760
94MP0000639_abnormal_adrenal_gland0.55680847
95MP0000751_myopathy0.54462457
96MP0004087_abnormal_muscle_fiber0.54291320
97MP0003075_altered_response_to0.53686191
98MP0005408_hypopigmentation0.52820313
99MP0005220_abnormal_exocrine_pancreas0.51498395
100MP0002210_abnormal_sex_determination0.51365625
101MP0008260_abnormal_autophagy0.50918720
102MP0000230_abnormal_systemic_arterial0.50340976
103MP0004043_abnormal_pH_regulation0.50237472
104MP0000653_abnormal_sex_gland0.49452727
105MP0002928_abnormal_bile_duct0.48291069
106MP0001730_embryonic_growth_arrest0.47532331
107MP0002282_abnormal_trachea_morphology0.46787928
108MP0002106_abnormal_muscle_physiology0.45741922
109MP0005375_adipose_tissue_phenotype0.45451514
110MP0005076_abnormal_cell_differentiation0.45360332
111MP0003638_abnormal_response/metabolism_0.43982646
112MP0004147_increased_porphyrin_level0.42694880
113MP0004859_abnormal_synaptic_plasticity0.42328388
114MP0009115_abnormal_fat_cell0.42146898
115MP0003633_abnormal_nervous_system0.41678496
116MP0001984_abnormal_olfaction0.39883717
117MP0002090_abnormal_vision0.39518188
118MP0002136_abnormal_kidney_physiology0.39451746
119MP0002970_abnormal_white_adipose0.39202674
120MP0005166_decreased_susceptibility_to0.38259270
121MP0001765_abnormal_ion_homeostasis0.38064601
122MP0009780_abnormal_chondrocyte_physiolo0.37949992
123MP0002069_abnormal_eating/drinking_beha0.36622141
124MP0002909_abnormal_adrenal_gland0.35218714
125MP0005395_other_phenotype0.35205485
126MP0009672_abnormal_birth_weight0.34686119
127MP0006276_abnormal_autonomic_nervous0.34169227
128MP0005330_cardiomyopathy0.33135208
129MP0008873_increased_physiological_sensi0.32677160
130MP0005595_abnormal_vascular_smooth0.32119048
131MP0002269_muscular_atrophy0.31794149
132MP0003879_abnormal_hair_cell0.31562093
133MP0009053_abnormal_anal_canal0.31341722
134MP0009745_abnormal_behavioral_response0.31268657
135MP0003631_nervous_system_phenotype0.30194867
136MP0005167_abnormal_blood-brain_barrier0.29939442
137MP0005452_abnormal_adipose_tissue0.29858079
138MP0005464_abnormal_platelet_physiology0.29801604
139MP0004883_abnormal_blood_vessel0.29112560
140MP0002168_other_aberrant_phenotype0.29067182

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)6.90156812
2Abnormality of aromatic amino acid family metabolism (HP:0004338)6.78027590
3Intrahepatic cholestasis (HP:0001406)6.77586930
4Prolonged partial thromboplastin time (HP:0003645)6.02192050
5Xanthomatosis (HP:0000991)6.01410733
6Abnormality of monocarboxylic acid metabolism (HP:0010996)5.92521464
7Hypobetalipoproteinemia (HP:0003563)5.90636622
8Hyperlipoproteinemia (HP:0010980)5.35661437
9Abnormality of the heme biosynthetic pathway (HP:0010472)5.27664098
10Complement deficiency (HP:0004431)4.92004507
11Hyperammonemia (HP:0001987)4.56625763
12Hypolipoproteinemia (HP:0010981)4.54668853
13Osteomalacia (HP:0002749)4.51794079
14Hyperglycinemia (HP:0002154)4.48540208
15Ketosis (HP:0001946)4.47009847
16Epidermoid cyst (HP:0200040)4.44045995
17Joint hemorrhage (HP:0005261)4.35394044
18Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.16922065
19Hyperglycinuria (HP:0003108)4.14397866
20Hypoalphalipoproteinemia (HP:0003233)4.11178558
21Abnormality of the common coagulation pathway (HP:0010990)4.10234042
22Abnormality of serine family amino acid metabolism (HP:0010894)4.06528832
23Abnormality of glycine metabolism (HP:0010895)4.06528832
24Abnormality of glutamine family amino acid metabolism (HP:0010902)3.93808478
25Hypoglycemic coma (HP:0001325)3.93402175
26Abnormality of aspartate family amino acid metabolism (HP:0010899)3.83942949
27Abnormality of sulfur amino acid metabolism (HP:0004339)3.83717529
28Abnormality of methionine metabolism (HP:0010901)3.79920848
29Fat malabsorption (HP:0002630)3.69570363
30Abnormality of fatty-acid metabolism (HP:0004359)3.54719665
31Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.49574507
32Abnormality of complement system (HP:0005339)3.48083959
33Ketoacidosis (HP:0001993)3.42743095
34Hypercholesterolemia (HP:0003124)3.42511081
35Conjugated hyperbilirubinemia (HP:0002908)3.42402277
36Polycythemia (HP:0001901)3.41698124
37Abnormality of the intrinsic pathway (HP:0010989)3.35109168
38Hyperbilirubinemia (HP:0002904)3.27046805
39Abnormality of pyrimidine metabolism (HP:0004353)3.15082442
40Delayed CNS myelination (HP:0002188)3.10258574
41Hypochromic microcytic anemia (HP:0004840)3.02094161
42Spontaneous abortion (HP:0005268)3.01457897
43Abnormality of serum amino acid levels (HP:0003112)2.99304564
44Metabolic acidosis (HP:0001942)2.86108868
45Abnormality of nucleobase metabolism (HP:0010932)2.82424385
46Skin nodule (HP:0200036)2.81212984
47Hepatocellular carcinoma (HP:0001402)2.80868620
48Hypochromic anemia (HP:0001931)2.75749198
49Acanthocytosis (HP:0001927)2.75520788
50Gout (HP:0001997)2.71531401
51Abnormality of dicarboxylic acid metabolism (HP:0010995)2.71271671
52Dicarboxylic aciduria (HP:0003215)2.71271671
53Abnormality of purine metabolism (HP:0004352)2.66095356
54Abnormal gallbladder morphology (HP:0012437)2.64758170
55Lethargy (HP:0001254)2.64031527
56Cholelithiasis (HP:0001081)2.64030052
57Steatorrhea (HP:0002570)2.63797268
58Cholecystitis (HP:0001082)2.61543780
59Abnormal gallbladder physiology (HP:0012438)2.61543780
60Cerebral edema (HP:0002181)2.56496796
61Myocardial infarction (HP:0001658)2.55972924
62Abnormality of reticulocytes (HP:0004312)2.55246914
63Potter facies (HP:0002009)2.52093603
64Facial shape deformation (HP:0011334)2.52093603
65Hypoglycemic seizures (HP:0002173)2.47568102
66Paralysis (HP:0003470)2.46335835
67Neonatal onset (HP:0003623)2.41927981
68Sensorimotor neuropathy (HP:0007141)2.35065776
69Vascular calcification (HP:0004934)2.34180511
70Systemic lupus erythematosus (HP:0002725)2.33398201
71Toxemia of pregnancy (HP:0100603)2.32062243
72Irritability (HP:0000737)2.30850846
73Brushfield spots (HP:0001088)2.27034980
74Poikilocytosis (HP:0004447)2.25725632
75Mitral stenosis (HP:0001718)2.23376128
76Amyloidosis (HP:0011034)2.22332382
77Spastic diplegia (HP:0001264)2.21200370
78Vomiting (HP:0002013)2.20661237
79Abnormal hemoglobin (HP:0011902)2.20309135
80Broad alveolar ridges (HP:0000187)2.18167626
81Malnutrition (HP:0004395)2.17048373
82Purpura (HP:0000979)2.16668823
83Status epilepticus (HP:0002133)2.16626151
84Diaphragmatic weakness (HP:0009113)2.16188090
85Nephritis (HP:0000123)2.13686860
86Hyperinsulinemic hypoglycemia (HP:0000825)2.11787982
87Abnormality of the gallbladder (HP:0005264)2.10988454
88Pancreatitis (HP:0001733)2.07801663
89Microcytic anemia (HP:0001935)2.07410945
90Pancreatic islet-cell hyperplasia (HP:0004510)2.06796080
91Late onset (HP:0003584)2.06435719
92Cardiovascular calcification (HP:0011915)2.05869348
93Generalized aminoaciduria (HP:0002909)2.05509826
94Glomerulonephritis (HP:0000099)2.04292830
95Hyperventilation (HP:0002883)2.03679570
96Enlarged kidneys (HP:0000105)2.03084382
97Prenatal maternal abnormality (HP:0002686)2.01933774
98Renal cortical cysts (HP:0000803)1.95730914
99Abnormality of the Achilles tendon (HP:0005109)1.93281376
100Hemorrhage of the eye (HP:0011885)1.91492102
101Bifid scrotum (HP:0000048)1.89146587
102Hydroxyprolinuria (HP:0003080)1.88887627
103Abnormality of proline metabolism (HP:0010907)1.88887627
104Rickets (HP:0002748)1.87798283
105Thrombophlebitis (HP:0004418)1.87240796
106Abnormality of transition element cation homeostasis (HP:0011030)1.86728168
107Esophageal varix (HP:0002040)1.86042170
108Hyperuricemia (HP:0002149)1.85314527
109Increased purine levels (HP:0004368)1.85314527
110Increased serum pyruvate (HP:0003542)1.84942664
111Broad palm (HP:0001169)1.84847454
112Menorrhagia (HP:0000132)1.84831583
113Gingival bleeding (HP:0000225)1.83654933
114Opisthotonus (HP:0002179)1.82986158
115Recurrent gram-negative bacterial infections (HP:0005420)1.81814468
116Proximal tubulopathy (HP:0000114)1.81513900
117Alkalosis (HP:0001948)1.80493179
118Reticulocytosis (HP:0001923)1.77325929
119Confusion (HP:0001289)1.76877407
120Hypertriglyceridemia (HP:0002155)1.76682781
121Abnormality of the lumbar spine (HP:0100712)1.76059071
122Hypophosphatemic rickets (HP:0004912)1.75232294
123Acute hepatic failure (HP:0006554)1.74690699
124Widely patent fontanelles and sutures (HP:0004492)1.72384020
125Submucous cleft hard palate (HP:0000176)1.71597632
126Vaginal fistula (HP:0004320)1.70964119
127Hepatoblastoma (HP:0002884)1.68369413
128Abnormality of urine glucose concentration (HP:0011016)1.68199645
129Glycosuria (HP:0003076)1.68199645
130Rhabdomyolysis (HP:0003201)1.66961939
131Abnormal tarsal ossification (HP:0008369)1.65608448
132Asymmetric septal hypertrophy (HP:0001670)1.64977540
133Neoplasm of the liver (HP:0002896)1.64415866
134Ileus (HP:0002595)1.63439720
135Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.63160864
136Arthropathy (HP:0003040)1.63139750
137Hyperkalemia (HP:0002153)1.62761696
138Impulsivity (HP:0100710)1.57972095
139Back pain (HP:0003418)1.57296580
140Abnormality of iron homeostasis (HP:0011031)1.56505058

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK6.16955000
2EIF2AK13.94650166
3SIK13.68564032
4FGFR43.32302532
5MAP2K43.26748731
6CDK123.18302766
7AKT33.03992008
8WNK12.91960164
9ERN12.88676561
10OBSCN2.82214531
11INSRR2.81303085
12DAPK22.65098085
13PLK42.64433979
14DYRK1B2.55122899
15EPHA42.53150467
16ERBB42.13141999
17TAOK32.03551856
18PKN21.86235266
19BRD41.75514067
20TRIB31.74331809
21PINK11.69412149
22PRPF4B1.60704697
23MAP3K41.60419630
24MST1R1.59851644
25PNCK1.54013259
26MAPK111.51403472
27DYRK31.49250118
28CAMK1D1.45240088
29PDK31.43675477
30PDK41.43675477
31NTRK31.41259778
32MAP3K71.37701303
33CAMK1G1.37683212
34TYRO31.25568316
35SGK11.23252099
36BRAF1.22948744
37FGFR21.17883646
38ABL21.17841504
39PRKAA21.15202443
40FRK1.14536820
41KSR21.13531594
42PIK3CG1.12127705
43DDR21.10513570
44STK41.09858331
45MAPK121.09579929
46TAOK21.08354822
47PRKCZ1.07794646
48BMX1.07706948
49FLT31.05082254
50SGK31.03687683
51JAK21.02376167
52CAMKK10.99956325
53SGK20.97229215
54MAP2K70.96200932
55PRKCG0.94357778
56PLK20.94239676
57PDPK10.92656453
58MAP3K90.91973420
59FGFR10.91217099
60PRKAA10.90335662
61SGK4940.90154867
62SGK2230.90154867
63PRKACG0.88829445
64MINK10.88278830
65STK380.88162053
66GRK60.86962875
67CDK70.86585568
68PIK3CA0.85821493
69CDK40.81923831
70DAPK10.81641140
71MTOR0.80778666
72RET0.80556288
73LATS10.80357828
74CAMK2G0.79316762
75RIPK10.78430586
76PHKG10.78089556
77PHKG20.78089556
78TTN0.77814938
79PDK10.76962469
80PTK60.76347842
81PDGFRA0.75704494
82MAP2K30.75153072
83MAPK40.74825747
84JAK10.74513283
85MAP2K60.74278441
86ERBB20.73852599
87MAP3K130.73252710
88MARK10.72360363
89PAK60.72283754
90MAP3K30.72011094
91TYK20.70789319
92NTRK10.68526960
93LATS20.68224958
94NEK90.67298371
95PAK30.66154284
96PTK2B0.64782667
97MAP3K20.63577388
98MAP2K10.62122287
99MAP3K60.61224160
100STK38L0.61128696
101RPS6KA10.60840019
102UHMK10.60723670
103BRSK10.59522677
104CAMK40.58955589
105KDR0.58791362
106AKT20.57621652
107MAP3K80.57534396
108PDK20.56415239
109RPS6KL10.56145054
110RPS6KC10.56145054
111TIE10.54592269
112GRK50.54486789
113CAMK2A0.53573082
114KSR10.53192907
115CSNK1E0.51674571
116CSNK1D0.51301203
117MAP3K10.50061820
118RPS6KA50.49771821
119PRKG10.49731399
120TESK10.49652147
121PIM10.49631863
122EEF2K0.49343123
123ICK0.49022679
124IRAK30.48460084
125RPS6KB10.48110477
126MAP3K50.47906102
127TAOK10.47777419
128PRKCQ0.47624204
129GSK3B0.46812814
130CDK20.46488902
131GSK3A0.46336885
132PKN10.45991295
133MAP3K110.45965697
134AKT10.44832051
135MAPK70.44797089
136WNK40.44229892
137CDK10.44184832
138PRKCH0.43813060
139SIK20.42675933
140MAP3K100.41633500
141LMTK20.40574941
142RPS6KA60.40372539
143RPS6KA30.40329085
144MET0.39924548
145MAPK140.39280526
146CSNK1G20.38259318
147FGFR30.38166157
148BRSK20.38066844
149CAMK10.36778853
150PRKCA0.36253669
151PRKACA0.34812686
152NEK10.34435106

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.35173514
2Nitrogen metabolism_Homo sapiens_hsa009103.69066410
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.46490508
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.14375189
5Arginine biosynthesis_Homo sapiens_hsa002203.00796122
6Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.81677288
7Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.72613178
8Fatty acid degradation_Homo sapiens_hsa000712.68676950
9Tryptophan metabolism_Homo sapiens_hsa003802.60436229
10Complement and coagulation cascades_Homo sapiens_hsa046102.54645545
11Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.51839646
12Butanoate metabolism_Homo sapiens_hsa006502.38812449
13Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.34919271
14Propanoate metabolism_Homo sapiens_hsa006402.25804970
15Peroxisome_Homo sapiens_hsa041462.11750817
16Fatty acid metabolism_Homo sapiens_hsa012122.07685980
17PPAR signaling pathway_Homo sapiens_hsa033202.04494616
18Pentose and glucuronate interconversions_Homo sapiens_hsa000402.04112069
19Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.87176736
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.79442055
21Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.76823060
222-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.76236953
23beta-Alanine metabolism_Homo sapiens_hsa004101.76228863
24Chemical carcinogenesis_Homo sapiens_hsa052041.69713168
25Histidine metabolism_Homo sapiens_hsa003401.68823358
26Steroid hormone biosynthesis_Homo sapiens_hsa001401.66103782
27Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.64524371
28Pyruvate metabolism_Homo sapiens_hsa006201.60005553
29Bile secretion_Homo sapiens_hsa049761.59939327
30Drug metabolism - other enzymes_Homo sapiens_hsa009831.50583535
31Staphylococcus aureus infection_Homo sapiens_hsa051501.50355870
32Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.49503315
33Retinol metabolism_Homo sapiens_hsa008301.47529241
34Phenylalanine metabolism_Homo sapiens_hsa003601.46827939
35Fatty acid elongation_Homo sapiens_hsa000621.41606944
36Caffeine metabolism_Homo sapiens_hsa002321.38916178
37Selenocompound metabolism_Homo sapiens_hsa004501.32892774
38Tyrosine metabolism_Homo sapiens_hsa003501.32647894
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.32594154
40Carbon metabolism_Homo sapiens_hsa012001.25784863
41Starch and sucrose metabolism_Homo sapiens_hsa005001.21633493
42Cysteine and methionine metabolism_Homo sapiens_hsa002701.20887437
43Sulfur metabolism_Homo sapiens_hsa009201.19479089
44Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.17962017
45ABC transporters_Homo sapiens_hsa020101.17787765
46Biosynthesis of amino acids_Homo sapiens_hsa012301.14834091
47Fat digestion and absorption_Homo sapiens_hsa049751.13724952
48Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.13358082
49Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.95158426
50Cyanoamino acid metabolism_Homo sapiens_hsa004600.94403595
51Steroid biosynthesis_Homo sapiens_hsa001000.94270472
52Folate biosynthesis_Homo sapiens_hsa007900.91585337
53Vitamin B6 metabolism_Homo sapiens_hsa007500.88129864
54Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.86529794
55Arginine and proline metabolism_Homo sapiens_hsa003300.84845831
56Fatty acid biosynthesis_Homo sapiens_hsa000610.83207207
57Glycerolipid metabolism_Homo sapiens_hsa005610.82745778
58Maturity onset diabetes of the young_Homo sapiens_hsa049500.82256602
59Lysine degradation_Homo sapiens_hsa003100.80469318
60Sulfur relay system_Homo sapiens_hsa041220.80031516
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.77834069
62Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.75621630
63Vitamin digestion and absorption_Homo sapiens_hsa049770.74715057
64Glycosaminoglycan degradation_Homo sapiens_hsa005310.56211379
65Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.50475572
66Glutathione metabolism_Homo sapiens_hsa004800.47067365
67Pentose phosphate pathway_Homo sapiens_hsa000300.46773361
68Metabolic pathways_Homo sapiens_hsa011000.42386605
69Other glycan degradation_Homo sapiens_hsa005110.39890317
70Renin-angiotensin system_Homo sapiens_hsa046140.39650443
71Prion diseases_Homo sapiens_hsa050200.35186992
72One carbon pool by folate_Homo sapiens_hsa006700.34672511
73Adipocytokine signaling pathway_Homo sapiens_hsa049200.34626668
74Glucagon signaling pathway_Homo sapiens_hsa049220.31935846
75N-Glycan biosynthesis_Homo sapiens_hsa005100.30925648
76Insulin resistance_Homo sapiens_hsa049310.30135515
77Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.26077194
78Circadian rhythm_Homo sapiens_hsa047100.25642026
79Glycerophospholipid metabolism_Homo sapiens_hsa005640.23561867
80Fructose and mannose metabolism_Homo sapiens_hsa000510.22933037
81Arachidonic acid metabolism_Homo sapiens_hsa005900.19260457
82Galactose metabolism_Homo sapiens_hsa000520.18848450
83alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.18832561
84Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.17618802
85AMPK signaling pathway_Homo sapiens_hsa041520.14090571
86Non-small cell lung cancer_Homo sapiens_hsa052230.13406069
87Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.08733643
88Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.08575719
89Linoleic acid metabolism_Homo sapiens_hsa005910.05813483
90Insulin signaling pathway_Homo sapiens_hsa049100.05145905
91Mineral absorption_Homo sapiens_hsa049780.05108124
92Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.03432525
93mTOR signaling pathway_Homo sapiens_hsa041500.03384231
94Thyroid hormone signaling pathway_Homo sapiens_hsa049190.02612997
95GABAergic synapse_Homo sapiens_hsa047270.02185964
96HIF-1 signaling pathway_Homo sapiens_hsa040660.00256732
97Regulation of autophagy_Homo sapiens_hsa04140-0.1704023
98Retrograde endocannabinoid signaling_Homo sapiens_hsa04723-0.1699990
99Glutamatergic synapse_Homo sapiens_hsa04724-0.1605772
100Insulin secretion_Homo sapiens_hsa04911-0.1557790
101Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960-0.1371969
102African trypanosomiasis_Homo sapiens_hsa05143-0.1321889
103Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.1292673
104Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.1192449
105Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.0967756
106Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.0954194
107Aldosterone synthesis and secretion_Homo sapiens_hsa04925-0.0934458
108Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014-0.0898137
109Nicotine addiction_Homo sapiens_hsa05033-0.0730704
110Thyroid hormone synthesis_Homo sapiens_hsa04918-0.0576751
111Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.0483598
112Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0359888
113Type II diabetes mellitus_Homo sapiens_hsa04930-0.0339283
114Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533-0.0097693
115Systemic lupus erythematosus_Homo sapiens_hsa05322-0.0013513

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