PAMR1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1bone trabecula formation (GO:0060346)5.80760487
2mesenchymal-epithelial cell signaling (GO:0060638)4.97428798
3skin morphogenesis (GO:0043589)4.93028385
4cell migration involved in heart development (GO:0060973)4.92383524
5type B pancreatic cell proliferation (GO:0044342)4.89577697
6endodermal cell differentiation (GO:0035987)4.84044362
7planar cell polarity pathway involved in neural tube closure (GO:0090179)4.65025767
8kidney mesenchyme development (GO:0072074)4.44558085
9regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)4.32884567
10COPI coating of Golgi vesicle (GO:0048205)4.30861680
11Golgi transport vesicle coating (GO:0048200)4.30861680
12regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)4.30103301
13metanephric mesenchyme development (GO:0072075)4.29436121
14synaptic vesicle docking involved in exocytosis (GO:0016081)4.25888878
15collagen metabolic process (GO:0032963)4.22916692
16collagen catabolic process (GO:0030574)4.06281394
17paraxial mesoderm development (GO:0048339)3.98639578
18extracellular fibril organization (GO:0043206)3.92113546
19multicellular organismal macromolecule metabolic process (GO:0044259)3.91916590
20tooth mineralization (GO:0034505)3.86812882
21endocardial cushion development (GO:0003197)3.81603557
22regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.76778589
23adhesion of symbiont to host (GO:0044406)3.70383177
24multicellular organismal catabolic process (GO:0044243)3.69621670
25multicellular organismal metabolic process (GO:0044236)3.69098863
26maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.67813955
27glutamate secretion (GO:0014047)3.66271228
28negative regulation of chondrocyte differentiation (GO:0032331)3.62104471
29negative regulation of smooth muscle cell migration (GO:0014912)3.60630846
30extracellular matrix disassembly (GO:0022617)3.56457073
31protein retention in ER lumen (GO:0006621)3.56218967
32basement membrane organization (GO:0071711)3.51587852
33outer ear morphogenesis (GO:0042473)3.50987783
34Wnt signaling pathway, planar cell polarity pathway (GO:0060071)3.41352668
35cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.41077157
36regulation of branching involved in salivary gland morphogenesis (GO:0060693)3.37141145
37heparan sulfate proteoglycan biosynthetic process (GO:0015012)3.34450736
38apoptotic cell clearance (GO:0043277)3.33878215
39extracellular regulation of signal transduction (GO:1900115)3.33749602
40extracellular negative regulation of signal transduction (GO:1900116)3.33749602
41neuron projection extension involved in neuron projection guidance (GO:1902284)3.32340212
42axon extension involved in axon guidance (GO:0048846)3.32340212
43regulation of establishment of planar polarity (GO:0090175)3.25472605
44vascular endothelial growth factor signaling pathway (GO:0038084)3.24421849
45positive regulation of endothelial cell apoptotic process (GO:2000353)3.21337735
46presynaptic membrane assembly (GO:0097105)3.20922667
47negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.16826025
48cellular response to vitamin D (GO:0071305)3.15888994
49regulation of synaptic vesicle exocytosis (GO:2000300)3.13797520
50postsynaptic membrane organization (GO:0001941)3.12664905
51barbed-end actin filament capping (GO:0051016)3.12254472
52cell adhesion mediated by integrin (GO:0033627)3.11483853
53extracellular matrix organization (GO:0030198)3.11437382
54pericardium development (GO:0060039)3.11110533
55fibril organization (GO:0097435)3.10549949
56extracellular structure organization (GO:0043062)3.10267684
57synaptic vesicle exocytosis (GO:0016079)3.10220681
58regulation of beta-amyloid formation (GO:1902003)3.08214598
59establishment of apical/basal cell polarity (GO:0035089)3.07543387
60substrate-dependent cell migration (GO:0006929)3.05913092
61negative regulation of axon extension involved in axon guidance (GO:0048843)3.05032969
62convergent extension (GO:0060026)3.05028936
63cochlea morphogenesis (GO:0090103)3.04580499
64protein heterotrimerization (GO:0070208)3.04039682
65G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.02794475
66response to gravity (GO:0009629)3.01113411
67sequestering of extracellular ligand from receptor (GO:0035581)3.00003171
68muscle cell migration (GO:0014812)2.99570809
69smooth muscle tissue development (GO:0048745)2.99206160
70cellular response to amino acid stimulus (GO:0071230)2.97951400
71collagen fibril organization (GO:0030199)2.97541969
72cell-substrate junction assembly (GO:0007044)2.96616438
73negative regulation of BMP signaling pathway (GO:0030514)2.95894472
74establishment of tissue polarity (GO:0007164)2.95555858
75establishment of planar polarity (GO:0001736)2.95555858
76middle ear morphogenesis (GO:0042474)2.93813866
77protein localization to cell surface (GO:0034394)2.92003991
78hemidesmosome assembly (GO:0031581)2.91334233
79peptide hormone processing (GO:0016486)2.91331761
80cell proliferation involved in metanephros development (GO:0072203)2.90513979
81endothelial cell morphogenesis (GO:0001886)2.87970516
82polarized epithelial cell differentiation (GO:0030859)2.86915496
83cell migration involved in sprouting angiogenesis (GO:0002042)2.85425528
84positive regulation of smoothened signaling pathway (GO:0045880)2.84587448
85negative regulation of embryonic development (GO:0045992)2.84283094
86positive regulation of fibroblast migration (GO:0010763)2.83690566
87neurotransmitter-gated ion channel clustering (GO:0072578)2.83256175
88substrate adhesion-dependent cell spreading (GO:0034446)2.82806786
89heparan sulfate proteoglycan metabolic process (GO:0030201)2.81969979
90retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.81781354
91non-canonical Wnt signaling pathway (GO:0035567)2.79338625
92venous blood vessel morphogenesis (GO:0048845)2.79301705
93positive regulation of vesicle fusion (GO:0031340)2.77262957
94presynaptic membrane organization (GO:0097090)2.75638037
95alanine transport (GO:0032328)2.74530028
96lung vasculature development (GO:0060426)2.73296094
97regulation of amyloid precursor protein catabolic process (GO:1902991)2.72002438
98proline transport (GO:0015824)2.71863377
99cerebellar granule cell differentiation (GO:0021707)2.71060512
100negative regulation of cartilage development (GO:0061037)2.70828865
101positive regulation of blood vessel endothelial cell migration (GO:0043536)2.68864236
102positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.66588315
103trabecula formation (GO:0060343)2.65310040
104mesodermal cell differentiation (GO:0048333)2.65157642
105positive regulation of mesenchymal cell proliferation (GO:0002053)2.65094601
106positive regulation of cartilage development (GO:0061036)2.63356469
107wound healing, spreading of epidermal cells (GO:0035313)2.62026428
108long-term synaptic potentiation (GO:0060291)2.61078239
109regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.61067197
110regulation of smooth muscle cell migration (GO:0014910)2.60346060
111vocalization behavior (GO:0071625)2.60150482
112mechanosensory behavior (GO:0007638)2.59257405
113regulation of synaptic vesicle transport (GO:1902803)2.57646708
114locomotory exploration behavior (GO:0035641)2.53339022
115keratan sulfate catabolic process (GO:0042340)2.48579099
116adhesion of symbiont to host cell (GO:0044650)2.46269793
117virion attachment to host cell (GO:0019062)2.46269793
118membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.46224156
119growth hormone secretion (GO:0030252)2.43606241
120positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.43526880
121positive regulation of glycogen biosynthetic process (GO:0045725)2.42602203
122peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.42527752
123regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.42094867
124negative regulation of hormone metabolic process (GO:0032351)2.39644748
125negative regulation of hormone biosynthetic process (GO:0032353)2.39644748
126endocrine pancreas development (GO:0031018)2.39455599
127insulin secretion (GO:0030073)2.38669666
128signal peptide processing (GO:0006465)2.34051917
129activation of protein kinase A activity (GO:0034199)2.32248604
130regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.31684441
131chondroitin sulfate catabolic process (GO:0030207)2.31588502
132detection of calcium ion (GO:0005513)2.30125966
133dermatan sulfate biosynthetic process (GO:0030208)2.28872605
134L-serine transport (GO:0015825)2.28828292
135toxin metabolic process (GO:0009404)2.28580135
136extracellular matrix assembly (GO:0085029)2.28393972
137exocrine pancreas development (GO:0031017)2.26322014
138regulation of short-term neuronal synaptic plasticity (GO:0048172)2.25989656
139renal tubule morphogenesis (GO:0061333)2.24040108
140positive regulation of cellular amide metabolic process (GO:0034250)2.21968879
141regulation of vesicle fusion (GO:0031338)2.21722637
142eosinophil chemotaxis (GO:0048245)2.18519480
143blood vessel maturation (GO:0001955)2.18498697
144synaptic vesicle maturation (GO:0016188)2.18442155
145dermatan sulfate metabolic process (GO:0030205)2.17815371
146neuron cell-cell adhesion (GO:0007158)2.17713979
147membrane repolarization during action potential (GO:0086011)2.17677477
148response to auditory stimulus (GO:0010996)2.16885943
149chondrocyte proliferation (GO:0035988)2.16294277
150negative regulation of osteoblast proliferation (GO:0033689)2.14679140
151regulation of glutamate receptor signaling pathway (GO:1900449)2.13123249
152neurotransmitter secretion (GO:0007269)2.12893716
153nitric oxide mediated signal transduction (GO:0007263)2.12726741
154regulation of extracellular matrix disassembly (GO:0010715)2.10974610
155positive regulation of neurotransmitter secretion (GO:0001956)2.10126829
156positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.10029762
157UDP-N-acetylglucosamine metabolic process (GO:0006047)2.08282569
158positive regulation of glycogen metabolic process (GO:0070875)2.08013414
159positive regulation of synapse assembly (GO:0051965)2.07383862
160glomerular basement membrane development (GO:0032836)2.05455449
161regulation of insulin secretion (GO:0050796)2.03228868
162regulation of positive chemotaxis (GO:0050926)2.02107284
163positive regulation of positive chemotaxis (GO:0050927)2.01935885
164positive regulation of cardiac muscle hypertrophy (GO:0010613)2.01739792
165positive regulation of muscle hypertrophy (GO:0014742)2.01739792
166peptide secretion (GO:0002790)2.01227121
167peptide hormone secretion (GO:0030072)1.99818503
168auditory behavior (GO:0031223)1.99294219
169negative regulation of synaptic transmission, GABAergic (GO:0032229)1.97654520
170neuronal action potential propagation (GO:0019227)1.97562205
171regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)1.97019995
172glomerular visceral epithelial cell development (GO:0072015)1.96890043
173cellular response to vitamin (GO:0071295)1.96817530
174regulation of calcium ion-dependent exocytosis (GO:0017158)1.96644235
175regulation of neurotransmitter secretion (GO:0046928)1.96549484
176positive regulation of excitatory postsynaptic membrane potential (GO:2000463)1.96119007
177regulation of ER to Golgi vesicle-mediated transport (GO:0060628)1.95788176
178protein localization to synapse (GO:0035418)1.95360546
179zinc ion transport (GO:0006829)1.94275508
180regulation of synaptic transmission, glutamatergic (GO:0051966)1.93887017

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human3.34651059
2GBX2_23144817_ChIP-Seq_PC3_Human3.04584616
3TP63_17297297_ChIP-ChIP_HaCaT_Human3.02316726
4RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.77205915
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.67007779
6EZH2_22144423_ChIP-Seq_EOC_Human2.62255923
7SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.61310208
8* BRD4_25478319_ChIP-Seq_HGPS_Human2.54276094
9SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.40278589
10SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.38882155
11EED_16625203_ChIP-ChIP_MESCs_Mouse2.35738641
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.35118502
13CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.18196493
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.09825783
15RNF2_18974828_ChIP-Seq_MESCs_Mouse2.07065822
16EZH2_18974828_ChIP-Seq_MESCs_Mouse2.07065822
17SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.05126030
18JARID2_20075857_ChIP-Seq_MESCs_Mouse2.03574627
19GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.02414148
20EZH2_27304074_Chip-Seq_ESCs_Mouse1.98040913
21EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.95712658
22ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.92987024
23JARID2_20064375_ChIP-Seq_MESCs_Mouse1.91458719
24PIAS1_25552417_ChIP-Seq_VCAP_Human1.91008096
25DROSHA_22980978_ChIP-Seq_HELA_Human1.80177636
26ELK3_25401928_ChIP-Seq_HUVEC_Human1.79779272
27RBPJ_22232070_ChIP-Seq_NCS_Mouse1.76718921
28CDX2_19796622_ChIP-Seq_MESCs_Mouse1.75274486
29CTBP2_25329375_ChIP-Seq_LNCAP_Human1.69822903
30THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.67935924
31SUZ12_27294783_Chip-Seq_ESCs_Mouse1.65695440
32SMC1_22415368_ChIP-Seq_MEFs_Mouse1.65440424
33EZH2_27294783_Chip-Seq_ESCs_Mouse1.64185085
34RNF2_27304074_Chip-Seq_ESCs_Mouse1.60203314
35PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.56898483
36RARG_19884340_ChIP-ChIP_MEFs_Mouse1.55231173
37NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.54731485
38NRF2_20460467_ChIP-Seq_MEFs_Mouse1.54731485
39SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.54201476
40TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.52730547
41ZNF217_24962896_ChIP-Seq_MCF-7_Human1.51802885
42SA1_22415368_ChIP-Seq_MEFs_Mouse1.51016503
43SMC3_22415368_ChIP-Seq_MEFs_Mouse1.48944337
44TP53_22127205_ChIP-Seq_IMR90_Human1.48341295
45HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.46394752
46SMAD4_21799915_ChIP-Seq_A2780_Human1.45232486
47TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.44977508
48ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.44893640
49AR_21572438_ChIP-Seq_LNCaP_Human1.44374858
50IKZF1_21737484_ChIP-ChIP_HCT116_Human1.43744762
51BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.42547327
52ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.42163913
53POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.40033401
54EP300_21415370_ChIP-Seq_HL-1_Mouse1.39620317
55P300_27058665_Chip-Seq_ZR-75-30cells_Human1.39474375
56PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.39243983
57NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.39003779
58NR3C1_23031785_ChIP-Seq_PC12_Mouse1.38853691
59* NFIB_24661679_ChIP-Seq_LUNG_Mouse1.36211567
60SMAD_19615063_ChIP-ChIP_OVARY_Human1.35175589
61ISL1_27105846_Chip-Seq_CPCs_Mouse1.34828223
62SOX9_24532713_ChIP-Seq_HFSC_Mouse1.32529591
63TP53_18474530_ChIP-ChIP_U2OS_Human1.32345279
64UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.32120005
65ZFP281_18757296_ChIP-ChIP_E14_Mouse1.32049681
66REST_21632747_ChIP-Seq_MESCs_Mouse1.31773111
67CLOCK_20551151_ChIP-Seq_293T_Human1.31604012
68FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.31246602
69TP53_23651856_ChIP-Seq_MEFs_Mouse1.30036201
70CJUN_26792858_Chip-Seq_BT549_Human1.29078910
71P300_19829295_ChIP-Seq_ESCs_Human1.26367351
72ERG_21242973_ChIP-ChIP_JURKAT_Human1.26312682
73* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.26116320
74UBF1/2_26484160_Chip-Seq_HMECs_Human1.24795743
75ESR1_21235772_ChIP-Seq_MCF-7_Human1.24498554
76BCAT_22108803_ChIP-Seq_LS180_Human1.22202768
77PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.21195213
78CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.18909745
79TOP2B_26459242_ChIP-Seq_MCF-7_Human1.18602868
80JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.17839665
81TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.17298055
82CTBP1_25329375_ChIP-Seq_LNCAP_Human1.17066672
83RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.16737145
84RXR_22108803_ChIP-Seq_LS180_Human1.16562599
85TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.15930444
86PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.15929018
87* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.15928750
88SOX2_21211035_ChIP-Seq_LN229_Gbm1.14898614
89AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.14844070
90DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.14566365
91ZFP281_27345836_Chip-Seq_ESCs_Mouse1.14399528
92PPAR_26484153_Chip-Seq_NCI-H1993_Human1.14114655
93ZFP57_27257070_Chip-Seq_ESCs_Mouse1.13151466
94TBX20_22328084_ChIP-Seq_HEART_Mouse1.12089901
95TBX20_22080862_ChIP-Seq_HEART_Mouse1.12089901
96ESR2_21235772_ChIP-Seq_MCF-7_Human1.10543666
97AR_25329375_ChIP-Seq_VCAP_Human1.10510436
98HIF1A_21447827_ChIP-Seq_MCF-7_Human1.09620929
99* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.09350322
100ARNT_22903824_ChIP-Seq_MCF-7_Human1.07155307
101OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07052987
102AHR_22903824_ChIP-Seq_MCF-7_Human1.06480051
103SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05850808
104ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.05705979
105WT1_19549856_ChIP-ChIP_CCG9911_Human1.05382654
106NR3C1_21868756_ChIP-Seq_MCF10A_Human1.03448946
107POU3F2_20337985_ChIP-ChIP_501MEL_Human1.02219168
108STAT6_21828071_ChIP-Seq_BEAS2B_Human1.01416195
109KDM2B_26808549_Chip-Seq_K562_Human1.01324961
110SMAD3_21741376_ChIP-Seq_EPCs_Human1.01173514
111SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.00650384
112AR_19668381_ChIP-Seq_PC3_Human1.00556857
113REST_18959480_ChIP-ChIP_MESCs_Mouse1.00357417
114* STAT3_23295773_ChIP-Seq_U87_Human0.99994201
115RING1B_27294783_Chip-Seq_ESCs_Mouse0.99946053
116NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.99264160
117SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.99197206
118SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.99193270
119SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.99193270
120TET1_21490601_ChIP-Seq_MESCs_Mouse0.98675523
121TBX3_20139965_ChIP-Seq_ESCs_Mouse0.97921049
122TBX3_20139965_ChIP-Seq_MESCs_Mouse0.97471566
123TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.96599976
124SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.96231840
125OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.96177976
126TP53_16413492_ChIP-PET_HCT116_Human0.95419640
127ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.95243221
128GATA2_21666600_ChIP-Seq_HMVEC_Human0.94813212
129TP53_20018659_ChIP-ChIP_R1E_Mouse0.94110782
130EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.92627626
131CBX2_27304074_Chip-Seq_ESCs_Mouse0.92515168
132* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.92085241
133MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.91706137
134SALL4_18804426_ChIP-ChIP_XEN_Mouse0.91678126
135* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.91582353
136NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.91210011
137RAD21_21589869_ChIP-Seq_MESCs_Mouse0.90805183
138P63_26484246_Chip-Seq_KERATINOCYTES_Human0.90576223
139TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.90547927
140WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.90379149
141RARB_27405468_Chip-Seq_BRAIN_Mouse0.89857057
142CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.89234908
143CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.88920249
144VDR_22108803_ChIP-Seq_LS180_Human0.88542248
145FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.88276162
146TCF4_23295773_ChIP-Seq_U87_Human0.88270929
147TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.87648667
148DNAJC2_21179169_ChIP-ChIP_NT2_Human0.86940463
149LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86164458
150YAP1_20516196_ChIP-Seq_MESCs_Mouse0.85306274
151SMAD4_21741376_ChIP-Seq_HESCs_Human0.84974099
152SOX2_20726797_ChIP-Seq_SW620_Human0.83944802
153TAF15_26573619_Chip-Seq_HEK293_Human0.83727525
154SMAD3_21741376_ChIP-Seq_HESCs_Human0.82154312
155* NANOG_18555785_Chip-Seq_ESCs_Mouse0.81070995

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen5.07210144
2MP0005503_abnormal_tendon_morphology3.89660565
3MP0005275_abnormal_skin_tensile3.76142640
4MP0009780_abnormal_chondrocyte_physiolo3.61652396
5MP0000013_abnormal_adipose_tissue3.54823443
6MP0002837_dystrophic_cardiac_calcinosis2.67457886
7MP0002909_abnormal_adrenal_gland2.57768616
8MP0010386_abnormal_urinary_bladder2.55498854
9MP0003183_abnormal_peptide_metabolism2.50088309
10MP0010030_abnormal_orbit_morphology2.24041514
11MP0003279_aneurysm2.10315619
12MP0003195_calcinosis2.09121236
13MP0002254_reproductive_system_inflammat2.04094258
14MP0001958_emphysema2.02836522
15MP0004859_abnormal_synaptic_plasticity1.97857437
16MP0003566_abnormal_cell_adhesion1.97347255
17MP0005645_abnormal_hypothalamus_physiol1.96233787
18MP0003283_abnormal_digestive_organ1.95440588
19MP0003705_abnormal_hypodermis_morpholog1.89094712
20MP0009384_cardiac_valve_regurgitation1.87101057
21MP0004272_abnormal_basement_membrane1.86394781
22MP0005084_abnormal_gallbladder_morpholo1.80432308
23MP0000767_abnormal_smooth_muscle1.78306209
24MP0003941_abnormal_skin_development1.71937096
25MP0000003_abnormal_adipose_tissue1.66782222
26MP0006054_spinal_hemorrhage1.64242160
27MP0000428_abnormal_craniofacial_morphol1.63240464
28MP0003122_maternal_imprinting1.62461077
29MP0003950_abnormal_plasma_membrane1.59248602
30MP0003880_abnormal_central_pattern1.56606908
31MP0003329_amyloid_beta_deposits1.56285363
32MP0004858_abnormal_nervous_system1.55809876
33MP0003091_abnormal_cell_migration1.54953550
34MP0002138_abnormal_hepatobiliary_system1.52931190
35MP0003635_abnormal_synaptic_transmissio1.51901046
36MP0005023_abnormal_wound_healing1.51752652
37MP0002896_abnormal_bone_mineralization1.51608936
38MP0004270_analgesia1.50968192
39MP0005379_endocrine/exocrine_gland_phen1.46483836
40MP0005257_abnormal_intraocular_pressure1.46021653
41MP0002295_abnormal_pulmonary_circulatio1.44658192
42MP0001243_abnormal_dermal_layer1.42339781
43MP0001944_abnormal_pancreas_morphology1.42220748
44MP0005220_abnormal_exocrine_pancreas1.41922320
45MP0002876_abnormal_thyroid_physiology1.40326779
46MP0001849_ear_inflammation1.36979347
47MP0005508_abnormal_skeleton_morphology1.36247854
48MP0002928_abnormal_bile_duct1.34306932
49MP0002108_abnormal_muscle_morphology1.27079755
50MP0004043_abnormal_pH_regulation1.26320250
51MP0001502_abnormal_circadian_rhythm1.25217879
52MP0003385_abnormal_body_wall1.24396477
53MP0000049_abnormal_middle_ear1.23511046
54MP0008004_abnormal_stomach_pH1.22165161
55MP0003045_fibrosis1.18475921
56MP0002734_abnormal_mechanical_nocicepti1.18455440
57MP0009745_abnormal_behavioral_response1.17128634
58MP0009053_abnormal_anal_canal1.17026919
59MP0005390_skeleton_phenotype1.16996767
60MP0002063_abnormal_learning/memory/cond1.15839968
61MP0005623_abnormal_meninges_morphology1.15570181
62MP0002064_seizures1.14991912
63MP0005646_abnormal_pituitary_gland1.14079449
64MP0002572_abnormal_emotion/affect_behav1.13880137
65MP0002736_abnormal_nociception_after1.09987935
66MP0001299_abnormal_eye_distance/1.09950842
67MP0001968_abnormal_touch/_nociception1.09033642
68MP0001501_abnormal_sleep_pattern1.08183066
69MP0000163_abnormal_cartilage_morphology1.02354548
70MP0000762_abnormal_tongue_morphology1.01937305
71MP0003300_gastrointestinal_ulcer1.00238011
72MP0002693_abnormal_pancreas_physiology0.99207533
73MP0003252_abnormal_bile_duct0.96905793
74MP0002060_abnormal_skin_morphology0.96506735
75MP0002168_other_aberrant_phenotype0.95960355
76MP0001348_abnormal_lacrimal_gland0.95080885
77MP0000432_abnormal_head_morphology0.94883522
78MP0009046_muscle_twitch0.93363544
79MP0005171_absent_coat_pigmentation0.93148635
80MP0000751_myopathy0.91859270
81MP0002877_abnormal_melanocyte_morpholog0.91729491
82MP0003879_abnormal_hair_cell0.91451885
83MP0010368_abnormal_lymphatic_system0.91074843
84MP0010352_gastrointestinal_tract_polyps0.89974914
85MP0001664_abnormal_digestion0.89395858
86MP0001440_abnormal_grooming_behavior0.89219445
87MP0000733_abnormal_muscle_development0.88713981
88MP0005197_abnormal_uvea_morphology0.88554513
89MP0003633_abnormal_nervous_system0.86590973
90MP0003868_abnormal_feces_composition0.86576967
91MP0003115_abnormal_respiratory_system0.86194106
92MP0000538_abnormal_urinary_bladder0.84576367
93MP0001542_abnormal_bone_strength0.83748687
94MP0004233_abnormal_muscle_weight0.83673957
95MP0008569_lethality_at_weaning0.83592373
96MP0005164_abnormal_response_to0.83544222
97MP0003755_abnormal_palate_morphology0.83038482
98MP0002078_abnormal_glucose_homeostasis0.82253180
99MP0003942_abnormal_urinary_system0.80303007
100MP0000230_abnormal_systemic_arterial0.80163764
101MP0002128_abnormal_blood_circulation0.79074314
102MP0002733_abnormal_thermal_nociception0.79048515
103MP0000604_amyloidosis0.78302735
104MP0002282_abnormal_trachea_morphology0.78160668
105MP0002933_joint_inflammation0.77407289
106MP0005365_abnormal_bile_salt0.77041875
107MP0005595_abnormal_vascular_smooth0.77020288
108MP0002116_abnormal_craniofacial_bone0.76862316
109MP0002932_abnormal_joint_morphology0.76369193
110MP0002115_abnormal_skeleton_extremities0.75696483
111MP0002557_abnormal_social/conspecific_i0.75416578
112MP0002233_abnormal_nose_morphology0.74686241
113MP0000759_abnormal_skeletal_muscle0.74682843
114MP0000534_abnormal_ureter_morphology0.74495371
115MP0002113_abnormal_skeleton_development0.73954179
116MP0002067_abnormal_sensory_capabilities0.73546514
117MP0000749_muscle_degeneration0.72949959
118MP0001765_abnormal_ion_homeostasis0.72232771
119MP0004130_abnormal_muscle_cell0.71835716
120MP0003690_abnormal_glial_cell0.71337027
121MP0003959_abnormal_lean_body0.70837856
122MP0001270_distended_abdomen0.70529600
123MP0000462_abnormal_digestive_system0.69472696
124MP0001915_intracranial_hemorrhage0.69425895
125MP0001970_abnormal_pain_threshold0.69393364
126MP0002133_abnormal_respiratory_system0.69175274
127MP0005388_respiratory_system_phenotype0.69175274
128MP0001614_abnormal_blood_vessel0.68995454
129MP0003075_altered_response_to0.68914415
130MP0002249_abnormal_larynx_morphology0.68602782
131MP0001756_abnormal_urination0.68565405
132MP0003448_altered_tumor_morphology0.68496866
133MP0000750_abnormal_muscle_regeneration0.67955856
134MP0002998_abnormal_bone_remodeling0.67460735
135MP0003935_abnormal_craniofacial_develop0.66649371
136MP0001175_abnormal_lung_morphology0.66496042
137MP0002114_abnormal_axial_skeleton0.66040356
138MP0008961_abnormal_basal_metabolism0.65544948
139MP0002272_abnormal_nervous_system0.64518180
140MP0004134_abnormal_chest_morphology0.64400738
141MP0002090_abnormal_vision0.63568453
142MP0009250_abnormal_appendicular_skeleto0.62740287
143MP0001879_abnormal_lymphatic_vessel0.62083388
144MP0002109_abnormal_limb_morphology0.61817031
145MP0003937_abnormal_limbs/digits/tail_de0.60206954
146MP0002697_abnormal_eye_size0.57670114
147MP0002177_abnormal_outer_ear0.56595243
148MP0005193_abnormal_anterior_eye0.55914212
149MP0003795_abnormal_bone_structure0.55817675
150MP0002089_abnormal_postnatal_growth/wei0.55200881
151MP0005369_muscle_phenotype0.54993065
152MP0000467_abnormal_esophagus_morphology0.54981453
153MP0004883_abnormal_blood_vessel0.50532357
154MP0002925_abnormal_cardiovascular_devel0.49338494
155MP0009840_abnormal_foam_cell0.47946112
156MP0001661_extended_life_span0.47518420
157MP0002092_abnormal_eye_morphology0.47511936
158MP0001533_abnormal_skeleton_physiology0.47305283
159MP0005620_abnormal_muscle_contractility0.46020932
160MP0002111_abnormal_tail_morphology0.43985282

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)4.82047772
2Slender build (HP:0001533)4.21533366
3Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.75699065
4Genu recurvatum (HP:0002816)3.57144760
5Epileptic encephalopathy (HP:0200134)3.49618145
6Premature rupture of membranes (HP:0001788)3.45553623
7Hyperinsulinemic hypoglycemia (HP:0000825)3.26938965
8Abnormality of calcium-phosphate metabolism (HP:0100530)3.19431757
9Hyperventilation (HP:0002883)3.19359485
10Bowel diverticulosis (HP:0005222)3.14989193
11Broad metatarsal (HP:0001783)3.11295243
12Coronal craniosynostosis (HP:0004440)3.09712930
13Cervical subluxation (HP:0003308)3.09142434
14Ketoacidosis (HP:0001993)3.06907160
15Aortic dissection (HP:0002647)3.04376112
16Peritonitis (HP:0002586)3.02572745
17Striae distensae (HP:0001065)3.01660049
18Hypoglycemic seizures (HP:0002173)2.93941626
19Megalencephaly (HP:0001355)2.85704259
20Soft skin (HP:0000977)2.82994263
21Vascular tortuosity (HP:0004948)2.82934659
22Aplasia involving bones of the extremities (HP:0009825)2.78640477
23Aplasia involving bones of the upper limbs (HP:0009823)2.78640477
24Aplasia of the phalanges of the hand (HP:0009802)2.78640477
25Arterial tortuosity (HP:0005116)2.78148780
26Narrow nasal bridge (HP:0000446)2.77684708
27Wide anterior fontanel (HP:0000260)2.77674046
28Focal motor seizures (HP:0011153)2.76305297
29Abnormality of dentin (HP:0010299)2.74964905
30Gout (HP:0001997)2.73870120
31Ankle contracture (HP:0006466)2.73383569
32Atrophic scars (HP:0001075)2.71157250
33Cerebral aneurysm (HP:0004944)2.69925577
34Aortic aneurysm (HP:0004942)2.68020422
35Fragile skin (HP:0001030)2.66526089
36Overgrowth (HP:0001548)2.64477152
37Hypoglycemic coma (HP:0001325)2.63816780
38Follicular hyperkeratosis (HP:0007502)2.61400444
39Abnormality of skeletal muscle fiber size (HP:0012084)2.59970277
40Neonatal short-limb short stature (HP:0008921)2.55880155
41Symptomatic seizures (HP:0011145)2.55550595
42Elbow flexion contracture (HP:0002987)2.47068507
43Mitral stenosis (HP:0001718)2.46348275
44Osteolytic defects of the phalanges of the hand (HP:0009771)2.45737870
45Osteolytic defects of the hand bones (HP:0009699)2.45737870
46Epileptiform EEG discharges (HP:0011182)2.45262487
47Atonic seizures (HP:0010819)2.40463002
48Vertebral compression fractures (HP:0002953)2.40325276
49Late onset (HP:0003584)2.40291107
50Mitral regurgitation (HP:0001653)2.40189183
51Bladder diverticulum (HP:0000015)2.39575822
52Hyperextensible skin (HP:0000974)2.38721682
53Dilatation of the ascending aorta (HP:0005111)2.38519909
54Wrist flexion contracture (HP:0001239)2.38359109
55Increased connective tissue (HP:0009025)2.36684102
56Hyperglycemia (HP:0003074)2.35493521
57Mild short stature (HP:0003502)2.34690278
58Shallow orbits (HP:0000586)2.31905890
59Abnormality of the acetabulum (HP:0003170)2.31595229
60Aortic valve stenosis (HP:0001650)2.31440172
61EEG with generalized epileptiform discharges (HP:0011198)2.30475249
62Dysostosis multiplex (HP:0000943)2.27202359
63Abnormal delivery (HP:0001787)2.26364981
64Hypoventilation (HP:0002791)2.25248535
65Large for gestational age (HP:0001520)2.24995397
66Joint stiffness (HP:0001387)2.22375517
67Abnormal pancreas size (HP:0012094)2.21333573
68Round ear (HP:0100830)2.20406597
69Natal tooth (HP:0000695)2.18681141
70Bell-shaped thorax (HP:0001591)2.18607734
71Mildly elevated creatine phosphokinase (HP:0008180)2.18282246
72Hypsarrhythmia (HP:0002521)2.18278908
73Generalized amyotrophy (HP:0003700)2.17848636
74Pheochromocytoma (HP:0002666)2.16865871
75Spondylolisthesis (HP:0003302)2.16188072
76Mucopolysacchariduria (HP:0008155)2.15681996
77Urinary glycosaminoglycan excretion (HP:0003541)2.15681996
78Turricephaly (HP:0000262)2.12785908
79Limb-girdle muscle weakness (HP:0003325)2.10019709
80Mitral valve prolapse (HP:0001634)2.09822572
81Absent frontal sinuses (HP:0002688)2.09071375
82Hypercortisolism (HP:0001578)2.09011385
83Disproportionate tall stature (HP:0001519)2.08601488
84Camptodactyly of toe (HP:0001836)2.07414688
85Protruding ear (HP:0000411)2.03140528
86Ulnar bowing (HP:0003031)2.03085593
87Aneurysm (HP:0002617)2.02839738
88Deviation of the hallux (HP:0010051)2.02076527
89Mesomelia (HP:0003027)2.01268165
90Delayed cranial suture closure (HP:0000270)1.99634575
91Broad long bones (HP:0005622)1.99366746
92Osteoarthritis (HP:0002758)1.99304825
93Biconcave vertebral bodies (HP:0004586)1.99209373
94Breech presentation (HP:0001623)1.98460198
95Premature skin wrinkling (HP:0100678)1.97742755
96Partial duplication of the phalanx of hand (HP:0009999)1.97433707
97Hypokalemia (HP:0002900)1.96583657
98Insulin-resistant diabetes mellitus (HP:0000831)1.96403237
99Wormian bones (HP:0002645)1.95736861
100Neuroendocrine neoplasm (HP:0100634)1.95410565
101Hepatoblastoma (HP:0002884)1.93926710
102Inguinal hernia (HP:0000023)1.93653656
103Abnormality of mucopolysaccharide metabolism (HP:0011020)1.92589867
104Abnormality of polysaccharide metabolism (HP:0011012)1.92589867
105Abnormality of glycosaminoglycan metabolism (HP:0004371)1.92589867
106Enlarged kidneys (HP:0000105)1.91113506
107Facial shape deformation (HP:0011334)1.90998267
108Potter facies (HP:0002009)1.90998267
109Long toe (HP:0010511)1.90517215
110Hallux valgus (HP:0001822)1.88766394
111Type 1 muscle fiber predominance (HP:0003803)1.88499630
112Ovoid vertebral bodies (HP:0003300)1.85704923
113Short nail (HP:0001799)1.85629963
114Increased variability in muscle fiber diameter (HP:0003557)1.85106597
115Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.84929536
116Neurofibrillary tangles (HP:0002185)1.83825073
117Retinal atrophy (HP:0001105)1.83687202
118Achilles tendon contracture (HP:0001771)1.82825939
119Infantile muscular hypotonia (HP:0008947)1.82406791
120Renal duplication (HP:0000075)1.82301973
121Broad ribs (HP:0000885)1.81449212
122Redundant skin (HP:0001582)1.80055464
123Delayed closure of the anterior fontanelle (HP:0001476)1.79091173
124Abnormality of skull ossification (HP:0002703)1.78297629
125Blue sclerae (HP:0000592)1.77932478
126Agitation (HP:0000713)1.77898524
127Cerebral inclusion bodies (HP:0100314)1.75932299
128Congenital glaucoma (HP:0001087)1.74711439
129Ectopia lentis (HP:0001083)1.74382113
130Nonimmune hydrops fetalis (HP:0001790)1.72858639
131Distal upper limb amyotrophy (HP:0007149)1.72738346
132Upper limb amyotrophy (HP:0009129)1.72738346
133Cardiovascular calcification (HP:0011915)1.69202058
134Neoplasm of the heart (HP:0100544)1.68227944
135Blue irides (HP:0000635)1.67714039
136Joint laxity (HP:0001388)1.67349099
137Focal seizures (HP:0007359)1.66812316
138Thoracolumbar scoliosis (HP:0002944)1.66065775
139Visual hallucinations (HP:0002367)1.65865030
140Pancreatic islet-cell hyperplasia (HP:0004510)1.65710865
141Patent foramen ovale (HP:0001655)1.65462619
142Torticollis (HP:0000473)1.65216464
143Partial duplication of thumb phalanx (HP:0009944)1.64883326
144Spinal rigidity (HP:0003306)1.64757874
145Spinal cord lesions (HP:0100561)1.64179030
146Syringomyelia (HP:0003396)1.64179030
147Hydroureter (HP:0000072)1.63274665
148Hypoplasia of the odontoid process (HP:0003311)1.62274380
149Aortic regurgitation (HP:0001659)1.62191016
150Skin nodule (HP:0200036)1.61012480
151Tarsal synostosis (HP:0008368)1.60964704
152Flared iliac wings (HP:0002869)1.60862452
153Arachnodactyly (HP:0001166)1.60461240
154Ketosis (HP:0001946)1.60302799
155Osteopenia (HP:0000938)1.57753761
156Oligomenorrhea (HP:0000876)1.57414980
157Abnormality of the pancreatic islet cells (HP:0006476)1.57348963
158Abnormality of endocrine pancreas physiology (HP:0012093)1.57348963

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.03715810
2INSRR3.21851648
3MAPK153.08878825
4EPHA43.02177200
5DAPK22.96187261
6PRKD32.68999933
7LMTK22.56415201
8PAK22.54613670
9NTRK32.33320420
10NEK92.17098933
11LATS22.04356887
12LIMK12.01340462
13FRK1.98003945
14DDR21.92165409
15MAP3K121.89996889
16CAMKK21.82823715
17AKT31.80084734
18CDK191.76574598
19WNK31.72878189
20TESK11.70302547
21LATS11.65349475
22TRIB31.63889167
23DAPK11.62694755
24GRK71.58018010
25CCNB11.56506093
26PAK41.54211512
27SIK11.53078830
28MAP3K91.49875691
29STK381.47271464
30MAP2K71.44358772
31MAP3K41.44355320
32ERN11.43117429
33FLT31.42362873
34PDGFRA1.41677081
35FER1.38469479
36MYLK1.37551637
37PLK21.37467496
38ERBB41.28403499
39KIT1.28142191
40PHKG11.26409386
41PHKG21.26409386
42NTRK11.24028085
43MOS1.19617821
44GRK11.18483915
45PDK31.17645170
46PDK41.17645170
47EPHA31.16175592
48ROCK21.14669182
49PRKCH1.12315365
50PAK31.09698230
51ABL21.08737706
52OXSR11.08625512
53MAP3K21.07874795
54PIK3CG1.07832135
55EPHB21.07368924
56ADRBK21.06341688
57NTRK21.04861474
58MAP3K61.02713130
59SGK4941.02588577
60SGK2231.02588577
61SGK21.00599359
62CAMKK10.96871949
63PIM20.96526159
64TRPM70.96372160
65RPS6KA20.95420404
66EEF2K0.94844760
67SGK30.91981143
68CDC42BPA0.91174324
69PRKCE0.90901299
70WNK40.90896336
71ARAF0.90069365
72PDK20.87037664
73MAP2K40.86017148
74PTK2B0.83144895
75ADRBK10.80793280
76DAPK30.79262331
77CLK10.78987741
78MAP3K130.78661087
79MTOR0.78529589
80MAP2K10.77114140
81PRKG20.76302635
82HIPK20.75882133
83CDK50.74961071
84PTK20.73733497
85DYRK1B0.73471535
86UHMK10.71453003
87GSK3A0.70963619
88GRK50.70924494
89BMPR1B0.70820497
90EPHB10.70453042
91MAPK70.70384423
92PKN20.70014458
93MAP3K10.69465098
94BRAF0.65364976
95PRKD20.65235590
96TYRO30.64451249
97CAMK2B0.64133069
98ILK0.63305930
99KSR20.62847310
100STK30.62093238
101PRKCG0.61649663
102PAK60.61314959
103CAMK2A0.60563089
104TGFBR10.60424356
105SMG10.59469106
106BMX0.59256983
107MAPK130.58521003
108PAK10.58008573
109RPS6KL10.55354776
110RPS6KC10.55354776
111GRK60.54332632
112DMPK0.54135119
113PRKD10.53113688
114PTK60.49941872
115SGK10.47790887
116MET0.47450308
117MAP3K70.47209314
118MELK0.46929168
119ROCK10.46822042
120CAMK2D0.46481254
121PRPF4B0.46174126
122TTN0.45647759
123PRKCI0.41357609
124IRAK30.41340590
125MARK10.41303526
126CAMK1G0.41182438
127DYRK1A0.40678811
128MARK20.40397577
129ICK0.39156114
130FGFR40.38916269
131MINK10.38847397
132MAPK120.38789511
133TGFBR20.38625181
134RPS6KA60.38345638
135PDGFRB0.37144893
136TIE10.36791520
137FGFR10.36090912
138RIPK10.36043231
139STK38L0.35018225
140EPHA20.35007944
141SRC0.34205912
142CAMK2G0.34003276
143PDPK10.33919785
144KSR10.33563959
145CDK80.33311264
146TAOK30.33306856
147CAMK10.33009116
148TAOK20.32915172
149FGFR20.32796190
150WNK10.31983940
151NME10.31525861
152JAK10.31056264
153MAPK40.27732054
154CDK150.27197040
155INSR0.26790527
156CDK11A0.25666442
157MAP2K30.22676088

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049503.73787984
2Insulin secretion_Homo sapiens_hsa049112.78647134
3Synaptic vesicle cycle_Homo sapiens_hsa047212.33152525
4Basal cell carcinoma_Homo sapiens_hsa052172.21526943
5Vibrio cholerae infection_Homo sapiens_hsa051102.05573158
6Collecting duct acid secretion_Homo sapiens_hsa049661.77440420
7Regulation of actin cytoskeleton_Homo sapiens_hsa048101.76686156
8Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.76075165
9Amphetamine addiction_Homo sapiens_hsa050311.75265595
10Melanoma_Homo sapiens_hsa052181.66155829
11PI3K-Akt signaling pathway_Homo sapiens_hsa041511.65703399
12Protein digestion and absorption_Homo sapiens_hsa049741.63690257
13Hippo signaling pathway_Homo sapiens_hsa043901.60965191
14Nicotine addiction_Homo sapiens_hsa050331.60017157
15TGF-beta signaling pathway_Homo sapiens_hsa043501.56850072
16Protein export_Homo sapiens_hsa030601.55464641
17Cocaine addiction_Homo sapiens_hsa050301.55046342
18Adherens junction_Homo sapiens_hsa045201.53378398
19Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.51854207
20Circadian rhythm_Homo sapiens_hsa047101.50338141
21GABAergic synapse_Homo sapiens_hsa047271.49425472
22ECM-receptor interaction_Homo sapiens_hsa045121.46539266
23Circadian entrainment_Homo sapiens_hsa047131.46034457
24Small cell lung cancer_Homo sapiens_hsa052221.43468230
25Sulfur metabolism_Homo sapiens_hsa009201.37614443
26Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.34712628
27Pancreatic secretion_Homo sapiens_hsa049721.33652890
28Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.32537950
29Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.30728284
30MicroRNAs in cancer_Homo sapiens_hsa052061.29966863
31Pathways in cancer_Homo sapiens_hsa052001.29842990
32Morphine addiction_Homo sapiens_hsa050321.29531594
33Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.28944066
34Aldosterone synthesis and secretion_Homo sapiens_hsa049251.27670051
35Central carbon metabolism in cancer_Homo sapiens_hsa052301.26283726
36Rheumatoid arthritis_Homo sapiens_hsa053231.21460102
37Complement and coagulation cascades_Homo sapiens_hsa046101.21075049
38Gastric acid secretion_Homo sapiens_hsa049711.20232366
39Renin secretion_Homo sapiens_hsa049241.19387235
40Salivary secretion_Homo sapiens_hsa049701.18722856
41Type I diabetes mellitus_Homo sapiens_hsa049401.17075580
42Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.16730569
43Glutamatergic synapse_Homo sapiens_hsa047241.16665407
44Type II diabetes mellitus_Homo sapiens_hsa049301.15120122
45Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.13952278
46Long-term potentiation_Homo sapiens_hsa047201.12984333
47Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.12527407
48Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.09366531
49Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.07290549
50Phospholipase D signaling pathway_Homo sapiens_hsa040721.05815947
51Rap1 signaling pathway_Homo sapiens_hsa040151.05534279
52Glioma_Homo sapiens_hsa052141.03823343
53Tight junction_Homo sapiens_hsa045301.02309837
54Taste transduction_Homo sapiens_hsa047421.01565960
55Nitrogen metabolism_Homo sapiens_hsa009101.01046717
56Lysosome_Homo sapiens_hsa041421.00838444
57Thyroid hormone synthesis_Homo sapiens_hsa049181.00822346
58Dopaminergic synapse_Homo sapiens_hsa047281.00476504
59Prostate cancer_Homo sapiens_hsa052150.96905662
60Glucagon signaling pathway_Homo sapiens_hsa049220.95641506
61Dilated cardiomyopathy_Homo sapiens_hsa054140.94333064
62Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.93704077
63cAMP signaling pathway_Homo sapiens_hsa040240.91515111
64Chronic myeloid leukemia_Homo sapiens_hsa052200.91034582
65Vascular smooth muscle contraction_Homo sapiens_hsa042700.89774664
66Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.87539542
67Olfactory transduction_Homo sapiens_hsa047400.87049600
68Fatty acid biosynthesis_Homo sapiens_hsa000610.86459252
69SNARE interactions in vesicular transport_Homo sapiens_hsa041300.86112874
70Melanogenesis_Homo sapiens_hsa049160.84642201
71Starch and sucrose metabolism_Homo sapiens_hsa005000.84632666
72Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.83948871
73Calcium signaling pathway_Homo sapiens_hsa040200.83457123
74Notch signaling pathway_Homo sapiens_hsa043300.83099421
75Estrogen signaling pathway_Homo sapiens_hsa049150.82971720
76Glycosaminoglycan degradation_Homo sapiens_hsa005310.82871831
77Focal adhesion_Homo sapiens_hsa045100.81131908
78Prion diseases_Homo sapiens_hsa050200.80509104
79Leukocyte transendothelial migration_Homo sapiens_hsa046700.79690255
80Cholinergic synapse_Homo sapiens_hsa047250.79417380
81Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.79403214
82Serotonergic synapse_Homo sapiens_hsa047260.79342293
83N-Glycan biosynthesis_Homo sapiens_hsa005100.77897436
84cGMP-PKG signaling pathway_Homo sapiens_hsa040220.77236773
85Carbohydrate digestion and absorption_Homo sapiens_hsa049730.75915772
86Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.75779343
87Galactose metabolism_Homo sapiens_hsa000520.75420166
88Ras signaling pathway_Homo sapiens_hsa040140.74122203
89Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.74013412
90GnRH signaling pathway_Homo sapiens_hsa049120.73555784
91Fatty acid metabolism_Homo sapiens_hsa012120.73487866
92Fatty acid degradation_Homo sapiens_hsa000710.72508412
93Amoebiasis_Homo sapiens_hsa051460.72268794
94Oxytocin signaling pathway_Homo sapiens_hsa049210.71894705
95Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.69334253
96Endocytosis_Homo sapiens_hsa041440.67404293
97Phagosome_Homo sapiens_hsa041450.67320624
98Neurotrophin signaling pathway_Homo sapiens_hsa047220.66265555
99p53 signaling pathway_Homo sapiens_hsa041150.65246377
100Gap junction_Homo sapiens_hsa045400.64995241
101Thyroid hormone signaling pathway_Homo sapiens_hsa049190.63749468
102Other glycan degradation_Homo sapiens_hsa005110.63517917
103Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.63447339
104Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.62506414
105Insulin resistance_Homo sapiens_hsa049310.56628542
106Malaria_Homo sapiens_hsa051440.55509649
107Endometrial cancer_Homo sapiens_hsa052130.54258630
108Thyroid cancer_Homo sapiens_hsa052160.54031098
109Bladder cancer_Homo sapiens_hsa052190.53974640
110Longevity regulating pathway - mammal_Homo sapiens_hsa042110.53467953
111Platelet activation_Homo sapiens_hsa046110.52805440
112Long-term depression_Homo sapiens_hsa047300.52398122
113Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.51943565
114Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.51659122
115Axon guidance_Homo sapiens_hsa043600.51027941
116MAPK signaling pathway_Homo sapiens_hsa040100.49829378
117Hedgehog signaling pathway_Homo sapiens_hsa043400.48855073
118AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.47306107
119Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.46422165
120Vitamin digestion and absorption_Homo sapiens_hsa049770.46165022
121Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.45335055
122Pertussis_Homo sapiens_hsa051330.45147419
123Sphingolipid signaling pathway_Homo sapiens_hsa040710.44999836
124Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.44697428
125Renin-angiotensin system_Homo sapiens_hsa046140.43793984
126Bile secretion_Homo sapiens_hsa049760.43215857
127HTLV-I infection_Homo sapiens_hsa051660.43071250
128Shigellosis_Homo sapiens_hsa051310.42956537
129Wnt signaling pathway_Homo sapiens_hsa043100.42922366
130Regulation of autophagy_Homo sapiens_hsa041400.42032937
131Fructose and mannose metabolism_Homo sapiens_hsa000510.41342075
132Propanoate metabolism_Homo sapiens_hsa006400.41133821
133Choline metabolism in cancer_Homo sapiens_hsa052310.40682073
134Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.40397869
135Proteoglycans in cancer_Homo sapiens_hsa052050.39844224
136Renal cell carcinoma_Homo sapiens_hsa052110.39148080
137Ovarian steroidogenesis_Homo sapiens_hsa049130.39069765
138TNF signaling pathway_Homo sapiens_hsa046680.38732899
139Pancreatic cancer_Homo sapiens_hsa052120.38608170
140mTOR signaling pathway_Homo sapiens_hsa041500.38391973
141Sphingolipid metabolism_Homo sapiens_hsa006000.37890005
142Insulin signaling pathway_Homo sapiens_hsa049100.37611038
143Adipocytokine signaling pathway_Homo sapiens_hsa049200.37205924
144ErbB signaling pathway_Homo sapiens_hsa040120.35685790
145AMPK signaling pathway_Homo sapiens_hsa041520.32268957
146Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.30824910
147Glutathione metabolism_Homo sapiens_hsa004800.26872191
148Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.25669616
149Colorectal cancer_Homo sapiens_hsa052100.25544199
150Lysine degradation_Homo sapiens_hsa003100.25070815
151Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.24673876

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