PALM3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of gene silencing by miRNA (GO:0060964)5.55999542
2regulation of gene silencing by RNA (GO:0060966)5.55999542
3regulation of posttranscriptional gene silencing (GO:0060147)5.55999542
4L-serine metabolic process (GO:0006563)4.88733182
5pre-miRNA processing (GO:0031054)4.76230989
6nuclear pore organization (GO:0006999)4.69105645
7nuclear pore complex assembly (GO:0051292)4.60447079
8serine family amino acid catabolic process (GO:0009071)4.42351595
9histone H4-K12 acetylation (GO:0043983)4.41180062
10protein localization to kinetochore (GO:0034501)4.27422020
11mitotic metaphase plate congression (GO:0007080)4.25424751
12mitotic sister chromatid segregation (GO:0000070)4.19281661
13formation of translation preinitiation complex (GO:0001731)4.12511915
14DNA replication-dependent nucleosome assembly (GO:0006335)4.11413182
15DNA replication-dependent nucleosome organization (GO:0034723)4.11413182
16ribosome biogenesis (GO:0042254)4.05143602
17glycine metabolic process (GO:0006544)4.04869603
18mitotic nuclear envelope disassembly (GO:0007077)4.01413125
19ribosome assembly (GO:0042255)3.95777063
20serine family amino acid biosynthetic process (GO:0009070)3.94627513
21L-alpha-amino acid transmembrane transport (GO:1902475)3.92847556
22erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.92425484
23L-phenylalanine catabolic process (GO:0006559)3.92425484
24erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.87311265
25L-phenylalanine metabolic process (GO:0006558)3.87311265
26heterochromatin organization (GO:0070828)3.86144233
27somatic hypermutation of immunoglobulin genes (GO:0016446)3.82360178
28somatic diversification of immune receptors via somatic mutation (GO:0002566)3.82360178
29regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.80510507
30nuclear envelope disassembly (GO:0051081)3.78777052
31membrane disassembly (GO:0030397)3.78777052
32regulation of hippo signaling (GO:0035330)3.76228392
33DNA replication checkpoint (GO:0000076)3.74149068
34protein localization to chromosome, centromeric region (GO:0071459)3.71720326
35regulation of translational termination (GO:0006449)3.61416728
36glyoxylate metabolic process (GO:0046487)3.59911435
37urea metabolic process (GO:0019627)3.58681026
38paraxial mesoderm development (GO:0048339)3.57052134
39sister chromatid segregation (GO:0000819)3.56757429
40establishment of apical/basal cell polarity (GO:0035089)3.55291177
41histone H2A monoubiquitination (GO:0035518)3.53965061
42pore complex assembly (GO:0046931)3.52489354
43DNA replication initiation (GO:0006270)3.52032900
44regulation of translational fidelity (GO:0006450)3.50871867
45nucleobase biosynthetic process (GO:0046112)3.50506596
46metaphase plate congression (GO:0051310)3.48709334
47regulation of fibrinolysis (GO:0051917)3.44089411
48mitotic chromosome condensation (GO:0007076)3.41312983
49regulation of spindle organization (GO:0090224)3.40748175
50establishment or maintenance of monopolar cell polarity (GO:0061339)3.39235656
51establishment of monopolar cell polarity (GO:0061162)3.39235656
52regulation of mitotic spindle organization (GO:0060236)3.38773405
53trophectodermal cell differentiation (GO:0001829)3.34376122
54epoxygenase P450 pathway (GO:0019373)3.32862730
55negative regulation of histone methylation (GO:0031061)3.32516149
56regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.31429575
57regulation of helicase activity (GO:0051095)3.30809661
58maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.30127884
59protein carboxylation (GO:0018214)3.29220003
60peptidyl-glutamic acid carboxylation (GO:0017187)3.29220003
61intestinal epithelial cell development (GO:0060576)3.29130639
62positive regulation of chromosome segregation (GO:0051984)3.29084026
63omega-hydroxylase P450 pathway (GO:0097267)3.28389610
64exogenous drug catabolic process (GO:0042738)3.28269675
65anterior/posterior axis specification, embryo (GO:0008595)3.27897305
66determination of adult lifespan (GO:0008340)3.27434239
67establishment of integrated proviral latency (GO:0075713)3.27391333
68urea cycle (GO:0000050)3.27125126
69serine family amino acid metabolic process (GO:0009069)3.27013076
70mitotic G1 DNA damage checkpoint (GO:0031571)3.26384337
71regulation of sister chromatid cohesion (GO:0007063)3.26298249
72replication fork processing (GO:0031297)3.25827243
73histone arginine methylation (GO:0034969)3.25631085
74proline metabolic process (GO:0006560)3.23156267
75regulation of RNA export from nucleus (GO:0046831)3.23071526
76ribonucleoprotein complex biogenesis (GO:0022613)3.21338815
77complement activation, alternative pathway (GO:0006957)3.18195236
78DNA duplex unwinding (GO:0032508)3.18195159
79DNA geometric change (GO:0032392)3.17936898
80drug catabolic process (GO:0042737)3.17477859
81purine nucleobase biosynthetic process (GO:0009113)3.15709928
82folic acid-containing compound biosynthetic process (GO:0009396)3.13999437
83DNA unwinding involved in DNA replication (GO:0006268)3.13808577
84negative regulation of sterol transport (GO:0032372)3.11746769
85negative regulation of cholesterol transport (GO:0032375)3.11746769
86regulation of nuclear cell cycle DNA replication (GO:0033262)3.11651369
87regulation of telomere maintenance via telomerase (GO:0032210)3.11553928
88chromatin assembly (GO:0031497)3.10778278
89negative regulation of fibrinolysis (GO:0051918)3.10184708
90regulation of centrosome cycle (GO:0046605)3.09118947
91kinetochore assembly (GO:0051382)3.08306913
92planar cell polarity pathway involved in neural tube closure (GO:0090179)3.08002176
93establishment of chromosome localization (GO:0051303)3.07501636
94transcription from mitochondrial promoter (GO:0006390)3.07222042
95positive regulation of SMAD protein import into nucleus (GO:0060391)3.07120936
96protein complex localization (GO:0031503)3.06115314
97kinetochore organization (GO:0051383)3.04017504
98DNA strand elongation involved in DNA replication (GO:0006271)3.03760402
99histone H4-K8 acetylation (GO:0043982)3.02869465
100histone H4-K5 acetylation (GO:0043981)3.02869465
101nitrogen cycle metabolic process (GO:0071941)3.02815843
102regulation of protein activation cascade (GO:2000257)3.02757566
103convergent extension (GO:0060026)3.01474847
104spliceosomal tri-snRNP complex assembly (GO:0000244)3.01278002
105maturation of SSU-rRNA (GO:0030490)2.98635577
106positive regulation of mitotic sister chromatid separation (GO:1901970)2.97674084
107positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.97674084
108positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.97674084
109trivalent inorganic anion homeostasis (GO:0072506)2.96312775
110phosphate ion homeostasis (GO:0055062)2.96312775
111nuclear envelope organization (GO:0006998)2.96202695
112regulation of double-strand break repair via homologous recombination (GO:0010569)2.95916366
113IMP biosynthetic process (GO:0006188)2.94077221
114mitotic G1/S transition checkpoint (GO:0044819)2.93123576
115regulation of gene silencing (GO:0060968)2.92377814
116regulation of histone H3-K9 methylation (GO:0051570)2.90668723
117mRNA transport (GO:0051028)2.89092245
118lysine metabolic process (GO:0006553)2.87576429
119lysine catabolic process (GO:0006554)2.87576429
120proline biosynthetic process (GO:0006561)2.86747010
121mitochondrial DNA metabolic process (GO:0032042)2.86585508
122negative regulation of chromosome segregation (GO:0051985)2.86333182
123peptidyl-arginine omega-N-methylation (GO:0035247)2.85788047
124intracellular estrogen receptor signaling pathway (GO:0030520)2.85663157
125regulation of complement activation (GO:0030449)2.84687834
126embryonic process involved in female pregnancy (GO:0060136)2.84614937
127DNA strand elongation (GO:0022616)2.84468154
128chromatin assembly or disassembly (GO:0006333)2.84247337
129protein-DNA complex disassembly (GO:0032986)2.83406447
130nucleosome disassembly (GO:0006337)2.83406447
131regulation of chromosome segregation (GO:0051983)2.82343395
132rRNA processing (GO:0006364)2.81637430
133protein K6-linked ubiquitination (GO:0085020)2.80799076
134regulation of double-strand break repair (GO:2000779)2.80411709
135ethanol oxidation (GO:0006069)2.79928897
136negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.79773187
137maturation of 5.8S rRNA (GO:0000460)2.78845695
138folic acid metabolic process (GO:0046655)2.77672213
139intestinal cholesterol absorption (GO:0030299)2.77620002
140spindle assembly (GO:0051225)2.77602076
141regulation of stem cell maintenance (GO:2000036)2.77549807
142rRNA metabolic process (GO:0016072)2.75724987
143regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.71555402
144NADPH regeneration (GO:0006740)2.71262444
145regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.67383379
146cell fate commitment involved in formation of primary germ layer (GO:0060795)2.64552285
147imidazole-containing compound metabolic process (GO:0052803)2.63810342
148negative regulation of lipase activity (GO:0060192)2.63708824
149blood coagulation, intrinsic pathway (GO:0007597)2.62675551
150fibrinolysis (GO:0042730)2.62083079
151notochord development (GO:0030903)2.60675856
152homocysteine metabolic process (GO:0050667)2.60473933
153regulation of catenin import into nucleus (GO:0035412)2.56352001
154cellular modified amino acid catabolic process (GO:0042219)2.55329464
155biotin metabolic process (GO:0006768)2.55198737
156pentose-phosphate shunt (GO:0006098)2.54984965
157regulation of bile acid biosynthetic process (GO:0070857)2.52804006
158sexual reproduction (GO:0019953)2.52723151
159cysteine metabolic process (GO:0006534)2.51797352
160negative regulation of gene silencing (GO:0060969)2.51071260
161regulation of plasminogen activation (GO:0010755)2.50549498
162cellular glucuronidation (GO:0052695)2.49984854
163alpha-amino acid catabolic process (GO:1901606)2.43851273
164glutamate metabolic process (GO:0006536)2.43157420
165regulation of cell fate specification (GO:0042659)2.42979159
166triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.41014360
167regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.38813035
168negative regulation of catenin import into nucleus (GO:0035414)2.38778720
169negative regulation of androgen receptor signaling pathway (GO:0060766)2.38490949
170ethanol metabolic process (GO:0006067)2.37580475
171tetrahydrofolate metabolic process (GO:0046653)2.37042642
172cell-cell junction maintenance (GO:0045217)2.36106010
173uronic acid metabolic process (GO:0006063)2.33908120
174glucuronate metabolic process (GO:0019585)2.33908120
175phospholipid efflux (GO:0033700)2.33840890
176acetyl-CoA metabolic process (GO:0006084)2.33381990
177peptidyl-arginine N-methylation (GO:0035246)2.31036037
178peptidyl-arginine methylation (GO:0018216)2.31036037
179regulation of apoptotic cell clearance (GO:2000425)2.30146239
180drug metabolic process (GO:0017144)2.28773455
181response to misfolded protein (GO:0051788)2.28690394

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.97864353
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.40231004
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.94254653
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.70618672
5KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.42600307
6KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.42600307
7KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.42600307
8ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.27216819
9SMAD1_18555785_ChIP-Seq_MESCs_Mouse3.09629278
10MYC_19079543_ChIP-ChIP_MESCs_Mouse3.09040371
11E2F4_17652178_ChIP-ChIP_JURKAT_Human2.88771284
12POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.74358663
13FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.66497388
14NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.66218428
15MYC_19030024_ChIP-ChIP_MESCs_Mouse2.49966907
16EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.48709297
17NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.44854447
18NANOG_18555785_ChIP-Seq_MESCs_Mouse2.31150506
19MYC_18358816_ChIP-ChIP_MESCs_Mouse2.21677447
20TCF3_18692474_ChIP-Seq_MEFs_Mouse2.12466158
21STAT3_1855785_ChIP-Seq_MESCs_Mouse2.11235698
22ERG_21242973_ChIP-ChIP_JURKAT_Human2.11199586
23ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.10530016
24KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.09376049
25NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.09058360
26SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.07896093
27SALL1_21062744_ChIP-ChIP_HESCs_Human2.05388222
28NELFA_20434984_ChIP-Seq_ESCs_Mouse2.04102252
29CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.03427994
30TCF3_18692474_ChIP-Seq_MESCs_Mouse2.00843204
31POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.96735879
32SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.96651697
33KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.91907066
34SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.89104644
35ETS1_20019798_ChIP-Seq_JURKAT_Human1.83496303
36ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.82982687
37MYC_22102868_ChIP-Seq_BL_Human1.81547849
38XRN2_22483619_ChIP-Seq_HELA_Human1.80236879
39MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.79133380
40POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.77375938
41JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.75181381
42EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.73873848
43EGR1_19374776_ChIP-ChIP_THP-1_Human1.73126303
44MYCN_18555785_ChIP-Seq_MESCs_Mouse1.71319604
45AR_21909140_ChIP-Seq_LNCAP_Human1.69699141
46TP63_19390658_ChIP-ChIP_HaCaT_Human1.65883920
47CREB1_15753290_ChIP-ChIP_HEK293T_Human1.65801492
48PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.64837187
49NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.64450116
50RXR_22158963_ChIP-Seq_LIVER_Mouse1.63451862
51EST1_17652178_ChIP-ChIP_JURKAT_Human1.63010038
52E2F1_18555785_ChIP-Seq_MESCs_Mouse1.61025589
53NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.60616337
54NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.59652882
55MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.59010340
56SOX2_18555785_ChIP-Seq_MESCs_Mouse1.58902004
57KLF4_18555785_ChIP-Seq_MESCs_Mouse1.55948079
58E2F1_21310950_ChIP-Seq_MCF-7_Human1.54239742
59NANOG_21062744_ChIP-ChIP_HESCs_Human1.53310523
60YY1_21170310_ChIP-Seq_MESCs_Mouse1.53272692
61POU5F1_16518401_ChIP-PET_MESCs_Mouse1.52522398
62KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.51858913
63DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.50055448
64LXR_22292898_ChIP-Seq_THP-1_Human1.50016873
65E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.49553096
66* RACK7_27058665_Chip-Seq_MCF-7_Human1.48240781
67KDM5A_27292631_Chip-Seq_BREAST_Human1.45156523
68PPARA_22158963_ChIP-Seq_LIVER_Mouse1.44747395
69FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.43236562
70CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.42557573
71STAT6_21828071_ChIP-Seq_BEAS2B_Human1.41746943
72TTF2_22483619_ChIP-Seq_HELA_Human1.40564527
73GABP_19822575_ChIP-Seq_HepG2_Human1.36001819
74VDR_23849224_ChIP-Seq_CD4+_Human1.35314085
75SOX2_18692474_ChIP-Seq_MESCs_Mouse1.32976865
76DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.32065446
77SOX2_18692474_ChIP-Seq_MEFs_Mouse1.31769461
78POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.29888026
79CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.29511224
80THAP11_20581084_ChIP-Seq_MESCs_Mouse1.27639304
81NANOG_18692474_ChIP-Seq_MEFs_Mouse1.27515691
82* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.27478198
83NANOG_18692474_ChIP-Seq_MESCs_Mouse1.27475024
84HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.27462578
85ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.27349811
86CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.26966859
87GABP_17652178_ChIP-ChIP_JURKAT_Human1.26834269
88OCT4_18692474_ChIP-Seq_MEFs_Mouse1.26763910
89CTCF_27219007_Chip-Seq_Bcells_Human1.25638367
90NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.25286857
91TET1_21451524_ChIP-Seq_MESCs_Mouse1.24897168
92P68_20966046_ChIP-Seq_HELA_Human1.23396572
93CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.20810331
94* KDM2B_26808549_Chip-Seq_K562_Human1.20239589
95TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.20051086
96FOXP3_21729870_ChIP-Seq_TREG_Human1.19569943
97KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.19126001
98ESR1_15608294_ChIP-ChIP_MCF-7_Human1.18965079
99ESR2_21235772_ChIP-Seq_MCF-7_Human1.16306920
100YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.16028838
101ZFX_18555785_ChIP-Seq_MESCs_Mouse1.15670252
102TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.12189939
103CIITA_25753668_ChIP-Seq_RAJI_Human1.11598533
104KAP1_27257070_Chip-Seq_ESCs_Mouse1.11595556
105RARG_19884340_ChIP-ChIP_MEFs_Mouse1.11325920
106CLOCK_20551151_ChIP-Seq_293T_Human1.10177910
107EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.09678901
108WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.09400193
109DCP1A_22483619_ChIP-Seq_HELA_Human1.08966447
110CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.07270795
111SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.06258624
112CREB1_26743006_Chip-Seq_LNCaP_Human1.06256731
113PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.05782207
114ZFP281_18757296_ChIP-ChIP_E14_Mouse1.04882282
115SMC4_20622854_ChIP-Seq_HELA_Human1.04297597
116ZFP281_27345836_Chip-Seq_ESCs_Mouse1.03388214
117FOXP1_21924763_ChIP-Seq_HESCs_Human1.03124044
118SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.02555726
119RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01884803
120ESR1_21235772_ChIP-Seq_MCF-7_Human1.01521577
121PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.01449318
122SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.01092676
123THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.99290542
124MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.98077830
125NANOG_16518401_ChIP-PET_MESCs_Mouse0.98024205
126SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.97866652
127ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.97706755
128SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.97590614
129CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.95918462
130TFEB_21752829_ChIP-Seq_HELA_Human0.95871000
131SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.95402520
132ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.94056628
133SRY_22984422_ChIP-ChIP_TESTIS_Rat0.93691179
134EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.92250113
135ZNF263_19887448_ChIP-Seq_K562_Human0.91897773
136CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.91186769
137POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.91024550
138RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.90213108
139TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.89950872

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.64284959
2MP0004957_abnormal_blastocyst_morpholog4.18594914
3MP0003111_abnormal_nucleus_morphology4.11485446
4MP0008057_abnormal_DNA_replication4.02498192
5MP0010094_abnormal_chromosome_stability3.58643895
6MP0003077_abnormal_cell_cycle3.46155608
7MP0002139_abnormal_hepatobiliary_system3.36973235
8MP0002254_reproductive_system_inflammat2.80379917
9MP0001730_embryonic_growth_arrest2.69804619
10MP0010352_gastrointestinal_tract_polyps2.54321395
11MP0000678_abnormal_parathyroid_gland2.53986412
12MP0008058_abnormal_DNA_repair2.49408059
13MP0005365_abnormal_bile_salt2.47176703
14MP0003123_paternal_imprinting2.44106135
15MP0000350_abnormal_cell_proliferation2.38707346
16MP0002653_abnormal_ependyma_morphology2.37784826
17MP0008932_abnormal_embryonic_tissue2.33555660
18MP0002084_abnormal_developmental_patter2.32276106
19MP0000566_synostosis2.27994006
20MP0005380_embryogenesis_phenotype2.27075208
21MP0001672_abnormal_embryogenesis/_devel2.27075208
22MP0002085_abnormal_embryonic_tissue2.17933456
23MP0003195_calcinosis2.15714172
24MP0001666_abnormal_nutrient_absorption2.15297236
25MP0001849_ear_inflammation2.09136479
26MP0005360_urolithiasis2.08566008
27MP0001697_abnormal_embryo_size2.06712694
28MP0003984_embryonic_growth_retardation1.98663470
29MP0002086_abnormal_extraembryonic_tissu1.98022328
30MP0002088_abnormal_embryonic_growth/wei1.95965897
31MP0004264_abnormal_extraembryonic_tissu1.95884202
32MP0003890_abnormal_embryonic-extraembry1.95810054
33MP0004133_heterotaxia1.94536271
34MP0008875_abnormal_xenobiotic_pharmacok1.91846155
35MP0003119_abnormal_digestive_system1.88821473
36MP0008007_abnormal_cellular_replicative1.83712904
37MP0008877_abnormal_DNA_methylation1.82829126
38MP0003941_abnormal_skin_development1.82788946
39MP0004197_abnormal_fetal_growth/weight/1.80577121
40MP0005085_abnormal_gallbladder_physiolo1.74403348
41MP0002080_prenatal_lethality1.72471427
42MP0010030_abnormal_orbit_morphology1.71909112
43MP0003718_maternal_effect1.70101128
44MP0005076_abnormal_cell_differentiation1.63630695
45MP0003122_maternal_imprinting1.62659650
46MP0003121_genomic_imprinting1.59417181
47MP0003786_premature_aging1.55880326
48MP0001293_anophthalmia1.54272212
49MP0010307_abnormal_tumor_latency1.51087461
50MP0003315_abnormal_perineum_morphology1.43429379
51MP0003806_abnormal_nucleotide_metabolis1.43019490
52MP0003942_abnormal_urinary_system1.37567720
53MP0000490_abnormal_crypts_of1.34598030
54MP0003705_abnormal_hypodermis_morpholog1.33687352
55MP0009053_abnormal_anal_canal1.32470928
56MP0003566_abnormal_cell_adhesion1.28445468
57MP0003136_yellow_coat_color1.27226221
58MP0000537_abnormal_urethra_morphology1.26284728
59MP0002089_abnormal_postnatal_growth/wei1.25912511
60MP0004185_abnormal_adipocyte_glucose1.25452740
61MP0002396_abnormal_hematopoietic_system1.23046781
62MP0000313_abnormal_cell_death1.22246118
63MP0003567_abnormal_fetal_cardiomyocyte1.20251196
64MP0004233_abnormal_muscle_weight1.19879591
65MP0001188_hyperpigmentation1.18889029
66MP0005332_abnormal_amino_acid1.17233749
67MP0002019_abnormal_tumor_incidence1.14193345
68MP0006292_abnormal_olfactory_placode1.12729709
69MP0000049_abnormal_middle_ear1.10639910
70MP0004019_abnormal_vitamin_homeostasis1.09666244
71MP0002138_abnormal_hepatobiliary_system1.08629270
72MP0005023_abnormal_wound_healing1.07949567
73MP0001145_abnormal_male_reproductive1.07803717
74MP0002210_abnormal_sex_determination1.07693880
75MP0005670_abnormal_white_adipose1.07536456
76MP0005083_abnormal_biliary_tract1.05789538
77MP0005257_abnormal_intraocular_pressure1.04195271
78MP0000428_abnormal_craniofacial_morphol1.03554577
79MP0000432_abnormal_head_morphology1.02761857
80MP0003937_abnormal_limbs/digits/tail_de1.00381150
81MP0002111_abnormal_tail_morphology0.98381187
82MP0000579_abnormal_nail_morphology0.97782313
83MP0003861_abnormal_nervous_system0.97727136
84MP0000462_abnormal_digestive_system0.97575611
85MP0009840_abnormal_foam_cell0.95592105
86MP0009703_decreased_birth_body0.93733251
87MP0002697_abnormal_eye_size0.93433517
88MP0000534_abnormal_ureter_morphology0.93289921
89MP0001286_abnormal_eye_development0.91795221
90MP0005501_abnormal_skin_physiology0.91736873
91MP0004782_abnormal_surfactant_physiolog0.90816254
92MP0005623_abnormal_meninges_morphology0.90536021
93MP0003868_abnormal_feces_composition0.90203993
94MP0003755_abnormal_palate_morphology0.88853691
95MP0002796_impaired_skin_barrier0.87977787
96MP0003283_abnormal_digestive_organ0.87678527
97MP0002233_abnormal_nose_morphology0.87363324
98MP0003115_abnormal_respiratory_system0.87279070
99MP0003935_abnormal_craniofacial_develop0.87169917
100MP0001299_abnormal_eye_distance/0.85952132
101MP0009278_abnormal_bone_marrow0.85016932
102MP0003936_abnormal_reproductive_system0.84885167
103MP0001661_extended_life_span0.84613986
104MP0000653_abnormal_sex_gland0.83872363
105MP0005621_abnormal_cell_physiology0.83583680
106MP0002249_abnormal_larynx_morphology0.83498585
107MP0002092_abnormal_eye_morphology0.82656791
108MP0005384_cellular_phenotype0.81872341
109MP0002114_abnormal_axial_skeleton0.81635938
110MP0001348_abnormal_lacrimal_gland0.79458325
111MP0001929_abnormal_gametogenesis0.78996148
112MP0008770_decreased_survivor_rate0.78108952
113MP0003787_abnormal_imprinting0.78014761
114MP0003938_abnormal_ear_development0.77951262
115MP0000703_abnormal_thymus_morphology0.77884200
116MP0005377_hearing/vestibular/ear_phenot0.77497273
117MP0003878_abnormal_ear_physiology0.77497273
118MP0003221_abnormal_cardiomyocyte_apopto0.75863191
119MP0010329_abnormal_lipoprotein_level0.75563688
120MP0003763_abnormal_thymus_physiology0.73667941
121MP0001915_intracranial_hemorrhage0.73287743
122MP0000358_abnormal_cell_content/0.73019112
123MP0004858_abnormal_nervous_system0.72934250
124MP0009672_abnormal_birth_weight0.72911995
125MP0005666_abnormal_adipose_tissue0.72735920
126MP0010234_abnormal_vibrissa_follicle0.72205518
127MP0002925_abnormal_cardiovascular_devel0.71774570
128MP0002160_abnormal_reproductive_system0.70321137
129MP0003252_abnormal_bile_duct0.69988398
130MP0001545_abnormal_hematopoietic_system0.68223975
131MP0005397_hematopoietic_system_phenotyp0.68223975
132MP0009333_abnormal_splenocyte_physiolog0.66704944
133MP0002116_abnormal_craniofacial_bone0.66091674
134MP0002127_abnormal_cardiovascular_syste0.65915516
135MP0005395_other_phenotype0.64520375
136MP0000750_abnormal_muscle_regeneration0.64518097
137MP0000733_abnormal_muscle_development0.63700306
138MP0000003_abnormal_adipose_tissue0.63404504
139MP0002081_perinatal_lethality0.63337281
140MP0002161_abnormal_fertility/fecundity0.63317701

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)4.96826185
2Abnormality of monocarboxylic acid metabolism (HP:0010996)4.65532018
3Deep venous thrombosis (HP:0002625)4.36495830
4Prolonged partial thromboplastin time (HP:0003645)4.27609628
5Abnormality of the labia minora (HP:0012880)4.23448253
6Rib fusion (HP:0000902)3.91716600
7Abnormality of aromatic amino acid family metabolism (HP:0004338)3.75157413
8Abnormality of the astrocytes (HP:0100707)3.73939964
9Astrocytoma (HP:0009592)3.73939964
10Breast hypoplasia (HP:0003187)3.66302234
11Aplasia/hypoplasia of the humerus (HP:0006507)3.54269209
12Absent radius (HP:0003974)3.49541962
13Patellar aplasia (HP:0006443)3.47352070
14Birth length less than 3rd percentile (HP:0003561)3.46219321
15Rhabdomyosarcoma (HP:0002859)3.44478665
16Impulsivity (HP:0100710)3.43448091
17Hypobetalipoproteinemia (HP:0003563)3.43262163
18Short humerus (HP:0005792)3.33062173
19Aplasia involving forearm bones (HP:0009822)3.28195712
20Absent forearm bone (HP:0003953)3.28195712
21Aplasia/Hypoplasia of the patella (HP:0006498)3.24480283
22Neoplasm of the oral cavity (HP:0100649)3.21798505
23Selective tooth agenesis (HP:0001592)3.19036123
24Medulloblastoma (HP:0002885)3.17041243
25Chromsome breakage (HP:0040012)3.16677286
26Chromosomal breakage induced by crosslinking agents (HP:0003221)3.16486456
27Complement deficiency (HP:0004431)3.14695418
28Shawl scrotum (HP:0000049)3.09676926
29Choanal stenosis (HP:0000452)3.08427605
30Carpal bone hypoplasia (HP:0001498)3.03938821
31Glioma (HP:0009733)3.00159568
32Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.95816199
33Hyperphosphatemia (HP:0002905)2.92971018
34Facial hemangioma (HP:0000329)2.91214466
35Supernumerary spleens (HP:0009799)2.88903294
36Cortical dysplasia (HP:0002539)2.88377015
37Intestinal fistula (HP:0100819)2.85290457
38Neoplasm of striated muscle (HP:0009728)2.83484210
39Hyperglycinuria (HP:0003108)2.78689658
40Hyperglycinemia (HP:0002154)2.75711999
41Rectovaginal fistula (HP:0000143)2.73807428
42Rectal fistula (HP:0100590)2.73807428
43Osteomalacia (HP:0002749)2.71813845
44Abnormality of the lower motor neuron (HP:0002366)2.64874565
45Basal cell carcinoma (HP:0002671)2.63203563
46Abnormality of the ileum (HP:0001549)2.63002852
47Bronchomalacia (HP:0002780)2.61593364
48Abnormality of complement system (HP:0005339)2.60178773
49Meckel diverticulum (HP:0002245)2.57134461
50Premature ovarian failure (HP:0008209)2.54989326
51Hepatoblastoma (HP:0002884)2.54661749
52Abnormality of serine family amino acid metabolism (HP:0010894)2.52811265
53Abnormality of glycine metabolism (HP:0010895)2.52811265
54Absent thumb (HP:0009777)2.48457774
55Intrahepatic cholestasis (HP:0001406)2.44791281
56Conjugated hyperbilirubinemia (HP:0002908)2.44785744
57Abnormal number of incisors (HP:0011064)2.42154650
58Abdominal situs inversus (HP:0003363)2.38695081
59Abnormality of abdominal situs (HP:0011620)2.38695081
60Abnormality of the lacrimal duct (HP:0011481)2.36749503
61Spinal muscular atrophy (HP:0007269)2.36367667
62Multiple enchondromatosis (HP:0005701)2.36010408
63Septo-optic dysplasia (HP:0100842)2.34549286
64Cerebral hypomyelination (HP:0006808)2.34166067
65Colon cancer (HP:0003003)2.33156197
66Aplasia/Hypoplasia of the uvula (HP:0010293)2.33041631
67Gout (HP:0001997)2.28601331
68Missing ribs (HP:0000921)2.28292739
69Ulnar claw (HP:0001178)2.26029594
70Agnosia (HP:0010524)2.24719556
71Abnormality of chromosome stability (HP:0003220)2.23622175
72Ectopic kidney (HP:0000086)2.23036061
73Turricephaly (HP:0000262)2.22823823
74Anal stenosis (HP:0002025)2.20295901
75Degeneration of anterior horn cells (HP:0002398)2.16588104
76Abnormality of the anterior horn cell (HP:0006802)2.16588104
77Abnormality of the preputium (HP:0100587)2.15843877
78Vaginal fistula (HP:0004320)2.14643871
79Fused cervical vertebrae (HP:0002949)2.13698415
80Neonatal hypoglycemia (HP:0001998)2.13575289
81Rickets (HP:0002748)2.13489958
82Abnormality of pyrimidine metabolism (HP:0004353)2.13341698
83Tongue fasciculations (HP:0001308)2.12845017
84Partial duplication of thumb phalanx (HP:0009944)2.12397819
85Vertebral clefting (HP:0008428)2.10316382
86Muscle fibrillation (HP:0010546)2.09110736
87Rough bone trabeculation (HP:0100670)2.08415108
88Abnormal hair whorl (HP:0010721)2.08361694
89Vertebral fusion (HP:0002948)2.07577630
90Increased nuchal translucency (HP:0010880)2.07180946
91Supernumerary ribs (HP:0005815)2.05687331
92Absent septum pellucidum (HP:0001331)2.04504792
93Supernumerary bones of the axial skeleton (HP:0009144)2.01119061
94Bicornuate uterus (HP:0000813)2.00973367
95Trismus (HP:0000211)2.00170348
96Ulnar bowing (HP:0003031)1.99704979
97Shallow orbits (HP:0000586)1.99456545
98Bifid scrotum (HP:0000048)1.99349003
99Hypolipoproteinemia (HP:0010981)1.98791962
100Nasolacrimal duct obstruction (HP:0000579)1.98176139
101Facial cleft (HP:0002006)1.97745735
102Abnormality of the salivary glands (HP:0010286)1.96889154
103Prominent nose (HP:0000448)1.95406527
104Biliary tract neoplasm (HP:0100574)1.95283915
105Hemorrhage of the eye (HP:0011885)1.94931383
106Cafe-au-lait spot (HP:0000957)1.94457648
107Horseshoe kidney (HP:0000085)1.93217912
108Deviation of the thumb (HP:0009603)1.93029949
109Proximal placement of thumb (HP:0009623)1.92928484
110Sparse lateral eyebrow (HP:0005338)1.92834145
111High anterior hairline (HP:0009890)1.92597659
112Tetany (HP:0001281)1.92075231
113Hypercholesterolemia (HP:0003124)1.91697023
114Breast aplasia (HP:0100783)1.91411505
115Hypoparathyroidism (HP:0000829)1.91381397
116Hemivertebrae (HP:0002937)1.91134460
117Abnormality of sulfur amino acid metabolism (HP:0004339)1.91086366
118Esophageal atresia (HP:0002032)1.91004743
119Delayed puberty (HP:0000823)1.90997451
120Annular pancreas (HP:0001734)1.89633683
121Overriding aorta (HP:0002623)1.89205524
122Abnormality of the septum pellucidum (HP:0007375)1.88567072
123Heterotopia (HP:0002282)1.88182745
124Squamous cell carcinoma (HP:0002860)1.87596608
125Tracheoesophageal fistula (HP:0002575)1.84584530
126Abnormality of the intrinsic pathway (HP:0010989)1.83843758
127Myelodysplasia (HP:0002863)1.83737761
128Duodenal stenosis (HP:0100867)1.83553262
129Small intestinal stenosis (HP:0012848)1.83553262
130Patent foramen ovale (HP:0001655)1.83345500
131Duplication of thumb phalanx (HP:0009942)1.83206567
132Aplasia/Hypoplasia of the sternum (HP:0006714)1.82830761
133Dysautonomia (HP:0002459)1.81847597
134Abnormality of the nasolacrimal system (HP:0000614)1.81451213
135Spastic diplegia (HP:0001264)1.80632161
136Aplasia involving bones of the upper limbs (HP:0009823)1.80154423
137Aplasia of the phalanges of the hand (HP:0009802)1.80154423
138Aplasia involving bones of the extremities (HP:0009825)1.80154423
139Joint hemorrhage (HP:0005261)1.79328043
140Reticulocytopenia (HP:0001896)1.78771359
141Abnormal urine phosphate concentration (HP:0012599)1.78739455
142Hyperacusis (HP:0010780)1.77024003
143Volvulus (HP:0002580)1.76932108
144Myelomeningocele (HP:0002475)1.76125943
145Broad thumb (HP:0011304)1.75286853
146Gastrointestinal carcinoma (HP:0002672)1.75017141
147Malignant gastrointestinal tract tumors (HP:0006749)1.75017141
148Metaphyseal cupping (HP:0003021)1.75016146
149Atrophy/Degeneration involving motor neurons (HP:0007373)1.74255142
150Neoplasm of the pancreas (HP:0002894)1.73805407
151Abnormal trabecular bone morphology (HP:0100671)1.72663552
152Broad alveolar ridges (HP:0000187)1.72428191
153Spontaneous abortion (HP:0005268)1.72286157
154Aplasia/Hypoplasia of the breasts (HP:0010311)1.72265047
155Atresia of the external auditory canal (HP:0000413)1.70731785
156Short thumb (HP:0009778)1.69951174
157Broad metatarsal (HP:0001783)1.69499853
158Partial duplication of the phalanx of hand (HP:0009999)1.68363277
159Abnormal lung lobation (HP:0002101)1.68209669
160Abnormality of methionine metabolism (HP:0010901)1.66986144
161Bilateral microphthalmos (HP:0007633)1.66504311
162Arnold-Chiari malformation (HP:0002308)1.64441138
163Self-mutilation (HP:0000742)1.63900889
164Hypercalciuria (HP:0002150)1.62801662
165Generalized hypotonia (HP:0001290)1.62413641
166Coronal craniosynostosis (HP:0004440)1.62088927
167Synostosis involving the elbow (HP:0003938)1.60081918
168Humeroradial synostosis (HP:0003041)1.60081918
169Cholecystitis (HP:0001082)1.59851654
170Abnormal gallbladder physiology (HP:0012438)1.59851654
171Renovascular hypertension (HP:0100817)1.59593916
172Seborrheic dermatitis (HP:0001051)1.57825154
173Abnormality of serum amino acid levels (HP:0003112)1.57081310
174Abnormality of reticulocytes (HP:0004312)1.56729460
175Pseudobulbar signs (HP:0002200)1.56114419
176Reticulocytosis (HP:0001923)1.51595142
177Hypophosphatemic rickets (HP:0004912)1.51046020
178Nephroblastoma (Wilms tumor) (HP:0002667)1.50492558
179Nephrocalcinosis (HP:0000121)1.48652263

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK125.59214522
2CDC73.35547426
3EPHA23.13218343
4LATS23.04178861
5TRIB33.00965689
6TTK2.96242035
7SMG12.92713589
8WEE12.88119811
9BUB12.85770323
10NEK12.68877333
11NME12.53740083
12NEK22.52941765
13FGFR42.29048245
14CDK72.24527280
15MUSK2.21191114
16RPS6KB22.20982350
17STK38L2.11694292
18CHEK22.04645375
19SIK12.02420798
20CAMK1D1.99791561
21PLK11.97214291
22TSSK61.88312466
23VRK21.87610364
24TYRO31.82152514
25PBK1.77066299
26STK101.76925716
27AKT31.76591844
28CAMK1G1.72445040
29RIPK11.62616265
30PNCK1.59969306
31LATS11.55786774
32PLK41.54930767
33CHEK11.48754700
34ALK1.45786174
35ICK1.45408693
36SRPK11.41921336
37FGFR21.39118372
38MAPKAPK31.29259501
39AURKB1.28017431
40TNIK1.25077431
41MTOR1.24003607
42BMPR1B1.23287927
43MAP3K91.22167752
44PRKCI1.20722236
45CDK41.20120488
46TAF11.18252272
47ATR1.17456875
48AURKA1.16352649
49MAP3K81.15598339
50BRSK21.15036827
51CDK21.14891772
52MAP3K61.13686460
53TESK21.12610357
54PLK31.11110181
55PAK41.09961936
56PIM11.09523861
57CSNK1E1.07694158
58TAOK11.05488438
59BRD41.05471576
60DDR21.05043757
61STK381.02391459
62GRK61.01453022
63PRPF4B0.97187465
64ATM0.93836483
65MST1R0.92267970
66RPS6KA20.91219884
67EEF2K0.89503422
68CDK80.88718674
69DYRK30.86257550
70BRSK10.85802598
71MATK0.84559465
72CDK60.84044434
73MAP2K20.83955871
74STK30.81494995
75NTRK10.79540946
76DMPK0.78499216
77STK160.76887314
78WNK40.76728715
79MKNK10.75202422
80EIF2AK10.74974087
81CDK10.74506630
82PDGFRA0.72080524
83TAOK20.71467423
84CSNK2A20.68417962
85PTK60.68416372
86MELK0.65617326
87PRKG20.62973305
88MARK20.62014728
89AKT20.60930420
90MAP3K100.60508030
91PASK0.60506454
92MAP3K110.60019444
93MARK30.60008155
94SCYL20.59856655
95MAPK100.58984155
96NME20.58463693
97OXSR10.57023151
98ACVR1B0.56150270
99MET0.55998050
100PAK10.55098649
101CSNK1D0.52053680
102PRKD20.50791133
103MAPK140.50565879
104BMX0.50491133
105ERBB40.48348229
106DYRK20.48242971
107FGR0.47980368
108MKNK20.46457435
109MST40.46390414
110CDK190.45280443
111GSK3B0.44695922
112RPS6KA10.44536473
113SGK4940.44369230
114SGK2230.44369230
115BRAF0.42976308
116CDK11A0.42051135
117MAPK110.41884097
118STK40.41707178
119PAK60.41142271
120RAF10.38935534
121ILK0.38795825
122MAPK90.38774676
123AKT10.38136395
124RPS6KL10.38098343
125RPS6KC10.38098343
126CDK150.37585276
127PRKCG0.37582964
128CSNK2A10.37315164
129MAPK10.37088068
130PINK10.36493529
131ARAF0.35123951
132PTK20.34490624
133DAPK10.34103644
134PAK20.34057297
135CSK0.33322727
136PRKDC0.31236206
137PDK40.28436473
138PDK30.28436473
139KSR20.27962414
140WNK30.24797890
141FGFR10.24438233

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.47106532
2Mismatch repair_Homo sapiens_hsa034303.96566938
3RNA transport_Homo sapiens_hsa030133.73769754
4DNA replication_Homo sapiens_hsa030303.57416766
5Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.35492124
6Spliceosome_Homo sapiens_hsa030403.19083441
7RNA polymerase_Homo sapiens_hsa030202.80157802
8Cell cycle_Homo sapiens_hsa041102.71495800
9Base excision repair_Homo sapiens_hsa034102.60286317
10Basal transcription factors_Homo sapiens_hsa030222.43040429
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.42746426
12Nucleotide excision repair_Homo sapiens_hsa034202.42046972
13Homologous recombination_Homo sapiens_hsa034402.33849338
14mRNA surveillance pathway_Homo sapiens_hsa030152.32178320
15Caffeine metabolism_Homo sapiens_hsa002322.26302435
16Arginine biosynthesis_Homo sapiens_hsa002202.21903310
17One carbon pool by folate_Homo sapiens_hsa006702.17738686
18Fanconi anemia pathway_Homo sapiens_hsa034602.17633484
19Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.11252381
20Retinol metabolism_Homo sapiens_hsa008302.09158377
21p53 signaling pathway_Homo sapiens_hsa041152.05581831
22Pentose and glucuronate interconversions_Homo sapiens_hsa000402.05504388
23Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.01384484
24Primary bile acid biosynthesis_Homo sapiens_hsa001201.89550390
25Ribosome_Homo sapiens_hsa030101.89451158
26Complement and coagulation cascades_Homo sapiens_hsa046101.86727515
27Phenylalanine metabolism_Homo sapiens_hsa003601.85728289
28Proteasome_Homo sapiens_hsa030501.80878718
29RNA degradation_Homo sapiens_hsa030181.75965270
30Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.73769770
31Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.70876118
32Fatty acid degradation_Homo sapiens_hsa000711.61229295
33Hippo signaling pathway_Homo sapiens_hsa043901.58004834
34Tyrosine metabolism_Homo sapiens_hsa003501.56951799
35Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.56388057
36Pyrimidine metabolism_Homo sapiens_hsa002401.55374130
37Chemical carcinogenesis_Homo sapiens_hsa052041.52600852
38Steroid biosynthesis_Homo sapiens_hsa001001.47696232
39Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.47601183
40Pyruvate metabolism_Homo sapiens_hsa006201.46282945
41mTOR signaling pathway_Homo sapiens_hsa041501.41657555
42Drug metabolism - other enzymes_Homo sapiens_hsa009831.40383177
43Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.39193262
44Oocyte meiosis_Homo sapiens_hsa041141.37657108
45Bile secretion_Homo sapiens_hsa049761.37640380
46Vitamin B6 metabolism_Homo sapiens_hsa007501.35940709
47Non-homologous end-joining_Homo sapiens_hsa034501.31970183
48Thyroid cancer_Homo sapiens_hsa052161.30471277
49Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.27514887
50Steroid hormone biosynthesis_Homo sapiens_hsa001401.23407143
51Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.21426133
52Basal cell carcinoma_Homo sapiens_hsa052171.16841872
53Epstein-Barr virus infection_Homo sapiens_hsa051691.16671121
54Hedgehog signaling pathway_Homo sapiens_hsa043401.13850343
55Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.10894559
56Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.09445593
57Fat digestion and absorption_Homo sapiens_hsa049751.08108594
58MicroRNAs in cancer_Homo sapiens_hsa052061.08101808
59Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.08069206
60Histidine metabolism_Homo sapiens_hsa003401.06051623
61Cyanoamino acid metabolism_Homo sapiens_hsa004601.05586398
62Viral carcinogenesis_Homo sapiens_hsa052031.04698571
63Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.03520816
64Adherens junction_Homo sapiens_hsa045201.03114021
65Biosynthesis of amino acids_Homo sapiens_hsa012301.02493962
66Fructose and mannose metabolism_Homo sapiens_hsa000510.98989530
67Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.95926113
68Starch and sucrose metabolism_Homo sapiens_hsa005000.94002100
69Colorectal cancer_Homo sapiens_hsa052100.93070700
70Notch signaling pathway_Homo sapiens_hsa043300.90240830
712-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.90091385
72Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.89681258
73Prion diseases_Homo sapiens_hsa050200.89377864
74Fatty acid metabolism_Homo sapiens_hsa012120.88159166
75TGF-beta signaling pathway_Homo sapiens_hsa043500.86860080
76Vitamin digestion and absorption_Homo sapiens_hsa049770.84379931
77Tight junction_Homo sapiens_hsa045300.83558045
78Small cell lung cancer_Homo sapiens_hsa052220.83199235
79HTLV-I infection_Homo sapiens_hsa051660.80624173
80Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.79098366
81Butanoate metabolism_Homo sapiens_hsa006500.79003407
82Bladder cancer_Homo sapiens_hsa052190.76814098
83Linoleic acid metabolism_Homo sapiens_hsa005910.71510069
84Tryptophan metabolism_Homo sapiens_hsa003800.71345101
85Central carbon metabolism in cancer_Homo sapiens_hsa052300.69505546
86Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.68562937
87Wnt signaling pathway_Homo sapiens_hsa043100.68201680
88beta-Alanine metabolism_Homo sapiens_hsa004100.67396244
89Herpes simplex infection_Homo sapiens_hsa051680.65305729
90Cysteine and methionine metabolism_Homo sapiens_hsa002700.64877024
91PPAR signaling pathway_Homo sapiens_hsa033200.64702565
92Purine metabolism_Homo sapiens_hsa002300.63712474
93Endometrial cancer_Homo sapiens_hsa052130.61039557
94Pathways in cancer_Homo sapiens_hsa052000.60453254
95Antigen processing and presentation_Homo sapiens_hsa046120.59813513
96Arachidonic acid metabolism_Homo sapiens_hsa005900.58605787
97Thyroid hormone signaling pathway_Homo sapiens_hsa049190.57803040
98Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.57537468
99Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.56765943
100Lysine degradation_Homo sapiens_hsa003100.55968988
101Metabolic pathways_Homo sapiens_hsa011000.55497906
102Regulation of actin cytoskeleton_Homo sapiens_hsa048100.54910111
103Longevity regulating pathway - mammal_Homo sapiens_hsa042110.53207493
104Primary immunodeficiency_Homo sapiens_hsa053400.51331800
105Melanoma_Homo sapiens_hsa052180.50948759
106Prostate cancer_Homo sapiens_hsa052150.49936748
107Chronic myeloid leukemia_Homo sapiens_hsa052200.49672001
108Acute myeloid leukemia_Homo sapiens_hsa052210.47543776
109HIF-1 signaling pathway_Homo sapiens_hsa040660.47364528
110Transcriptional misregulation in cancer_Homo sapiens_hsa052020.45646415
111Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.45538843
112VEGF signaling pathway_Homo sapiens_hsa043700.44627349
113Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.41122650
114Peroxisome_Homo sapiens_hsa041460.40570498
115Glucagon signaling pathway_Homo sapiens_hsa049220.40111638
116Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.40057407
117Fatty acid elongation_Homo sapiens_hsa000620.39695497
118Pentose phosphate pathway_Homo sapiens_hsa000300.37997305
119Folate biosynthesis_Homo sapiens_hsa007900.37113469
120Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.36583172
121Non-small cell lung cancer_Homo sapiens_hsa052230.36068196
122Apoptosis_Homo sapiens_hsa042100.36002904
123Fatty acid biosynthesis_Homo sapiens_hsa000610.35491617
124Proteoglycans in cancer_Homo sapiens_hsa052050.35359241
125Arginine and proline metabolism_Homo sapiens_hsa003300.34388125
126FoxO signaling pathway_Homo sapiens_hsa040680.33875779
127Renal cell carcinoma_Homo sapiens_hsa052110.33828367
128Choline metabolism in cancer_Homo sapiens_hsa052310.33761761
129Propanoate metabolism_Homo sapiens_hsa006400.33716617
130Pancreatic cancer_Homo sapiens_hsa052120.32466342
131T cell receptor signaling pathway_Homo sapiens_hsa046600.32306337
132Systemic lupus erythematosus_Homo sapiens_hsa053220.32097261
133Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.30251344
134Selenocompound metabolism_Homo sapiens_hsa004500.30033019
135Thyroid hormone synthesis_Homo sapiens_hsa049180.29071608
136Maturity onset diabetes of the young_Homo sapiens_hsa049500.28684972
137PI3K-Akt signaling pathway_Homo sapiens_hsa041510.28508197
138ErbB signaling pathway_Homo sapiens_hsa040120.27760883
139Galactose metabolism_Homo sapiens_hsa000520.27582669
140Dorso-ventral axis formation_Homo sapiens_hsa043200.26731677
141Glutathione metabolism_Homo sapiens_hsa004800.26354599
142Carbon metabolism_Homo sapiens_hsa012000.26175489
143Shigellosis_Homo sapiens_hsa051310.25918065
144Sulfur relay system_Homo sapiens_hsa041220.25714673
145Rap1 signaling pathway_Homo sapiens_hsa040150.25362567
146Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.23754041
147Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.23284471
148Inositol phosphate metabolism_Homo sapiens_hsa005620.22777509
149Regulation of autophagy_Homo sapiens_hsa041400.21353347
150AMPK signaling pathway_Homo sapiens_hsa041520.21284905
151Insulin signaling pathway_Homo sapiens_hsa049100.21189373

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