PAK1IP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1maturation of SSU-rRNA (GO:0030490)4.92505530
2proteasome assembly (GO:0043248)4.69463219
3purine nucleobase biosynthetic process (GO:0009113)4.54291956
4nucleobase biosynthetic process (GO:0046112)4.45227597
5formation of translation preinitiation complex (GO:0001731)4.36857004
6mitotic metaphase plate congression (GO:0007080)4.36647216
7chaperone-mediated protein transport (GO:0072321)4.36505556
8establishment of integrated proviral latency (GO:0075713)4.33552431
9DNA replication checkpoint (GO:0000076)4.31796174
10ribosome biogenesis (GO:0042254)4.19930221
11DNA replication initiation (GO:0006270)4.15061250
12ribosome assembly (GO:0042255)4.11818389
13mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.11288580
14CENP-A containing nucleosome assembly (GO:0034080)4.07598408
15DNA deamination (GO:0045006)3.99880485
16ribosomal small subunit assembly (GO:0000028)3.98254442
17chromatin remodeling at centromere (GO:0031055)3.97314428
18negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.96587959
19rRNA modification (GO:0000154)3.95037764
20DNA double-strand break processing (GO:0000729)3.94665146
21anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.93437297
22maturation of 5.8S rRNA (GO:0000460)3.92780005
23ribonucleoprotein complex biogenesis (GO:0022613)3.91297890
24positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.90938308
25DNA strand elongation involved in DNA replication (GO:0006271)3.89575368
26regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.88709574
27cullin deneddylation (GO:0010388)3.81287716
28protein deneddylation (GO:0000338)3.78676412
29transcription elongation from RNA polymerase III promoter (GO:0006385)3.75701560
30termination of RNA polymerase III transcription (GO:0006386)3.75701560
31ribosomal large subunit biogenesis (GO:0042273)3.75590014
327-methylguanosine mRNA capping (GO:0006370)3.74827615
33DNA strand elongation (GO:0022616)3.74624151
34metaphase plate congression (GO:0051310)3.74081075
35telomere maintenance via semi-conservative replication (GO:0032201)3.70399949
36regulation of mitochondrial translation (GO:0070129)3.69560542
37transcription from mitochondrial promoter (GO:0006390)3.69311962
38rRNA processing (GO:0006364)3.67123661
397-methylguanosine RNA capping (GO:0009452)3.66996406
40RNA capping (GO:0036260)3.66996406
41negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.56745997
42negative regulation of ligase activity (GO:0051352)3.56745997
43ribosomal small subunit biogenesis (GO:0042274)3.54265063
44regulation of mitotic spindle checkpoint (GO:1903504)3.54168245
45regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.54168245
46rRNA metabolic process (GO:0016072)3.54002417
47positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.52171952
48mitochondrial RNA metabolic process (GO:0000959)3.51203779
49telomere maintenance via recombination (GO:0000722)3.50289234
50termination of RNA polymerase I transcription (GO:0006363)3.49164042
51DNA replication-independent nucleosome organization (GO:0034724)3.48649861
52DNA replication-independent nucleosome assembly (GO:0006336)3.48649861
53protein localization to kinetochore (GO:0034501)3.48066159
54DNA catabolic process, exonucleolytic (GO:0000738)3.48048398
55DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.47445278
56attachment of spindle microtubules to kinetochore (GO:0008608)3.44860800
57regulation of cellular amino acid metabolic process (GO:0006521)3.41883715
58intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.41761938
59signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.41761938
60energy coupled proton transport, down electrochemical gradient (GO:0015985)3.41709936
61ATP synthesis coupled proton transport (GO:0015986)3.41709936
62negative regulation of DNA-dependent DNA replication (GO:2000104)3.41295406
63signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.41042347
64signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.41042347
65signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.41042347
66mitotic nuclear envelope disassembly (GO:0007077)3.40596014
67transcription elongation from RNA polymerase I promoter (GO:0006362)3.40091321
68establishment of viral latency (GO:0019043)3.37660220
69mitochondrial respiratory chain complex assembly (GO:0033108)3.37365012
70rRNA methylation (GO:0031167)3.37166783
71respiratory chain complex IV assembly (GO:0008535)3.37081279
72spliceosomal snRNP assembly (GO:0000387)3.36407465
73protein targeting to mitochondrion (GO:0006626)3.35525972
74histone exchange (GO:0043486)3.35321197
75signal transduction involved in DNA damage checkpoint (GO:0072422)3.35165786
76signal transduction involved in DNA integrity checkpoint (GO:0072401)3.35165786
77positive regulation of ligase activity (GO:0051351)3.34496318
78transcription from RNA polymerase I promoter (GO:0006360)3.33147659
79transcription-coupled nucleotide-excision repair (GO:0006283)3.31760750
80signal transduction involved in cell cycle checkpoint (GO:0072395)3.30567138
81establishment of chromosome localization (GO:0051303)3.30325943
82DNA damage response, detection of DNA damage (GO:0042769)3.30294030
83IMP biosynthetic process (GO:0006188)3.29551095
84G1/S transition of mitotic cell cycle (GO:0000082)3.27893921
85cell cycle G1/S phase transition (GO:0044843)3.27893921
86mitotic recombination (GO:0006312)3.26936077
87spindle checkpoint (GO:0031577)3.25159877
88regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.24468387
89DNA replication-dependent nucleosome assembly (GO:0006335)3.22889568
90DNA replication-dependent nucleosome organization (GO:0034723)3.22889568
91pseudouridine synthesis (GO:0001522)3.22767789
92protein complex biogenesis (GO:0070271)3.20938889
93mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.20662302
94somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.18941918
95somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.18941918
96isotype switching (GO:0045190)3.18941918
97regulation of spindle organization (GO:0090224)3.18013823
98translational initiation (GO:0006413)3.16878728
99histone mRNA metabolic process (GO:0008334)3.16737232
100kinetochore organization (GO:0051383)3.16723777
101tRNA aminoacylation (GO:0043039)3.16717454
102amino acid activation (GO:0043038)3.16717454
103cellular component biogenesis (GO:0044085)3.15386215
104tRNA aminoacylation for protein translation (GO:0006418)3.15146982
105L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.14944392
106NADH dehydrogenase complex assembly (GO:0010257)3.14836940
107mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.14836940
108mitochondrial respiratory chain complex I assembly (GO:0032981)3.14836940
109replication fork processing (GO:0031297)3.14782881
110antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.14529507
111mitotic spindle checkpoint (GO:0071174)3.14189181
112translational termination (GO:0006415)3.14035334
113nuclear envelope disassembly (GO:0051081)3.13876668
114membrane disassembly (GO:0030397)3.13876668
115negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.10783861
116negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.10783861
117negative regulation of mitotic sister chromatid segregation (GO:0033048)3.10783861
118negative regulation of mitotic sister chromatid separation (GO:2000816)3.10783861
119negative regulation of sister chromatid segregation (GO:0033046)3.10783861
120viral transcription (GO:0019083)3.10328171
121telomere maintenance via telomere lengthening (GO:0010833)3.10071531
122protein neddylation (GO:0045116)3.09971303
123viral mRNA export from host cell nucleus (GO:0046784)3.09476247
124regulation of ubiquitin-protein transferase activity (GO:0051438)3.09147565
125transcription initiation from RNA polymerase I promoter (GO:0006361)3.07807005
126establishment of protein localization to mitochondrial membrane (GO:0090151)3.07599787
127DNA unwinding involved in DNA replication (GO:0006268)3.05948370
128nuclear pore organization (GO:0006999)3.04555958
129IMP metabolic process (GO:0046040)3.03671091
130kinetochore assembly (GO:0051382)3.01367371
131folic acid metabolic process (GO:0046655)2.99464353
132protein K6-linked ubiquitination (GO:0085020)2.99041649
133transcription elongation from RNA polymerase II promoter (GO:0006368)2.98770493
134exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.96597445
135regulation of ligase activity (GO:0051340)2.96169403
136antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.95827302
137nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.94558138
138folic acid-containing compound biosynthetic process (GO:0009396)2.92534268
139DNA-templated transcription, elongation (GO:0006354)2.91552069

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.11019734
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.47008904
3* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.01890514
4* GABP_17652178_ChIP-ChIP_JURKAT_Human3.69430621
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.61018568
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.58441713
7* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.54190685
8* ETS1_20019798_ChIP-Seq_JURKAT_Human3.33315279
9E2F4_17652178_ChIP-ChIP_JURKAT_Human3.26710842
10CREB1_15753290_ChIP-ChIP_HEK293T_Human3.12707291
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.98990275
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.96891747
13MYC_19030024_ChIP-ChIP_MESCs_Mouse2.95591884
14FOXM1_23109430_ChIP-Seq_U2OS_Human2.95583097
15FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.83735199
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.74586087
17* VDR_23849224_ChIP-Seq_CD4+_Human2.61325869
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.60530912
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.60400558
20NELFA_20434984_ChIP-Seq_ESCs_Mouse2.53035302
21XRN2_22483619_ChIP-Seq_HELA_Human2.37988243
22HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.36752572
23DCP1A_22483619_ChIP-Seq_HELA_Human2.29471380
24MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.27168791
25* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.26845380
26E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.22634543
27* FOXP3_21729870_ChIP-Seq_TREG_Human2.16201607
28ELF1_17652178_ChIP-ChIP_JURKAT_Human2.07642169
29GABP_19822575_ChIP-Seq_HepG2_Human2.06679689
30CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.04882923
31* ELK1_19687146_ChIP-ChIP_HELA_Human2.01919867
32THAP11_20581084_ChIP-Seq_MESCs_Mouse2.00975273
33PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.00115502
34AR_21909140_ChIP-Seq_LNCAP_Human1.98276350
35TTF2_22483619_ChIP-Seq_HELA_Human1.97653954
36POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.91991870
37SRF_21415370_ChIP-Seq_HL-1_Mouse1.90612163
38MYCN_18555785_ChIP-Seq_MESCs_Mouse1.89946055
39MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.89179060
40* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.84018630
41SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.83875628
42SALL1_21062744_ChIP-ChIP_HESCs_Human1.82501087
43YY1_21170310_ChIP-Seq_MESCs_Mouse1.82186838
44E2F1_21310950_ChIP-Seq_MCF-7_Human1.76207157
45MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.73263292
46NANOG_18555785_ChIP-Seq_MESCs_Mouse1.72996715
47YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.70539224
48ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.64349824
49* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.64101537
50SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.58347882
51* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.58208804
52TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.53691352
53PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.53661837
54ZFX_18555785_ChIP-Seq_MESCs_Mouse1.47323657
55TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.41830046
56PADI4_21655091_ChIP-ChIP_MCF-7_Human1.41351625
57* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.37974280
58KDM5A_27292631_Chip-Seq_BREAST_Human1.35888019
59NOTCH1_21737748_ChIP-Seq_TLL_Human1.35111958
60POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.33786721
61ZNF274_21170338_ChIP-Seq_K562_Hela1.32497563
62STAT3_1855785_ChIP-Seq_MESCs_Mouse1.26563286
63EWS_26573619_Chip-Seq_HEK293_Human1.26447287
64CIITA_25753668_ChIP-Seq_RAJI_Human1.24342033
65ERG_20887958_ChIP-Seq_HPC-7_Mouse1.22406458
66POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.21787466
67ELK1_22589737_ChIP-Seq_MCF10A_Human1.21197333
68* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.20353474
69VDR_22108803_ChIP-Seq_LS180_Human1.17873815
70* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.16724824
71TFEB_21752829_ChIP-Seq_HELA_Human1.16479346
72HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.15925799
73EGR1_19374776_ChIP-ChIP_THP-1_Human1.13990455
74NANOG_16153702_ChIP-ChIP_HESCs_Human1.13257979
75CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.10688176
76FLI1_27457419_Chip-Seq_LIVER_Mouse1.10280995
77ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.10191189
78FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.09987150
79BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.09610097
80* MYC_18940864_ChIP-ChIP_HL60_Human1.09377624
81* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.08534076
82RBPJ_22232070_ChIP-Seq_NCS_Mouse1.06629963
83E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.03685908
84DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.02822003
85FUS_26573619_Chip-Seq_HEK293_Human1.01998789
86POU5F1_16153702_ChIP-ChIP_HESCs_Human1.00060590
87SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.98031507
88SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.98010534
89* PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.97136923
90CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.97037939
91CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.96934406
92SOX2_18555785_ChIP-Seq_MESCs_Mouse0.94106123
93HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.91679133
94SOX2_16153702_ChIP-ChIP_HESCs_Human0.91355609
95KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.90929973
96* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.88821285
97SPI1_23547873_ChIP-Seq_NB4_Human0.87856229
98CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.87594296
99* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.85348681
100CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.85109143
101* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.84998227
102* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.83313173
103NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.82230040
104DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.82223682
105SOX17_20123909_ChIP-Seq_XEN_Mouse0.80346338
106PCGF2_27294783_Chip-Seq_ESCs_Mouse0.78589521
107HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.78562713
108ELF5_23300383_ChIP-Seq_T47D_Human0.77551855
109* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.77294561
110FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.77212904
111* KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.76768807
112OCT4_18692474_ChIP-Seq_MEFs_Mouse0.76419064
113* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.74597663
114NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.74451156
115IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.73794699
116TP63_19390658_ChIP-ChIP_HaCaT_Human0.73665819
117SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.73442523
118POU3F2_20337985_ChIP-ChIP_501MEL_Human0.72535155
119RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.68138434
120IRF1_19129219_ChIP-ChIP_H3396_Human0.65725348
121SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.65121505
122GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.64185832
123P300_19829295_ChIP-Seq_ESCs_Human0.61427991

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.28682867
2MP0010094_abnormal_chromosome_stability4.85140720
3MP0004957_abnormal_blastocyst_morpholog4.80378295
4MP0003111_abnormal_nucleus_morphology4.30423167
5MP0003077_abnormal_cell_cycle4.00330842
6MP0008058_abnormal_DNA_repair3.91662902
7MP0008057_abnormal_DNA_replication3.40831037
8MP0008877_abnormal_DNA_methylation3.17041814
9MP0003718_maternal_effect2.99738034
10MP0008932_abnormal_embryonic_tissue2.93637971
11MP0003786_premature_aging2.93162449
12MP0008007_abnormal_cellular_replicative2.86878960
13MP0003123_paternal_imprinting2.53186203
14MP0003806_abnormal_nucleotide_metabolis2.15935020
15MP0002396_abnormal_hematopoietic_system2.10369989
16MP0001730_embryonic_growth_arrest2.08051836
17MP0000350_abnormal_cell_proliferation1.99327206
18MP0009333_abnormal_splenocyte_physiolog1.90280541
19MP0002102_abnormal_ear_morphology1.81195903
20MP0003186_abnormal_redox_activity1.78338219
21MP0002210_abnormal_sex_determination1.64948055
22MP0006072_abnormal_retinal_apoptosis1.63240624
23MP0000490_abnormal_crypts_of1.62869028
24MP0008260_abnormal_autophagy1.62632698
25MP0002938_white_spotting1.56147680
26MP0004147_increased_porphyrin_level1.54244294
27MP0006292_abnormal_olfactory_placode1.53293162
28MP0003890_abnormal_embryonic-extraembry1.50744909
29MP0010307_abnormal_tumor_latency1.49215417
30MP0001697_abnormal_embryo_size1.46346195
31MP0000313_abnormal_cell_death1.43081325
32MP0005380_embryogenesis_phenotype1.40419217
33MP0001672_abnormal_embryogenesis/_devel1.40419217
34MP0002019_abnormal_tumor_incidence1.38973769
35MP0002080_prenatal_lethality1.37871075
36MP0002132_abnormal_respiratory_system1.36785954
37MP0003763_abnormal_thymus_physiology1.36378521
38MP0008789_abnormal_olfactory_epithelium1.36251036
39MP0003315_abnormal_perineum_morphology1.34815419
40MP0001145_abnormal_male_reproductive1.33326462
41MP0003195_calcinosis1.31822325
42MP0010352_gastrointestinal_tract_polyps1.29821967
43MP0001929_abnormal_gametogenesis1.28128149
44MP0005171_absent_coat_pigmentation1.28115037
45MP0000653_abnormal_sex_gland1.27343676
46MP0001119_abnormal_female_reproductive1.25388231
47MP0001542_abnormal_bone_strength1.21197432
48MP0003984_embryonic_growth_retardation1.20727041
49MP0005397_hematopoietic_system_phenotyp1.18918864
50MP0001545_abnormal_hematopoietic_system1.18918864
51MP0004808_abnormal_hematopoietic_stem1.18035137
52MP0002088_abnormal_embryonic_growth/wei1.16649014
53MP0009379_abnormal_foot_pigmentation1.15682253
54MP0005075_abnormal_melanosome_morpholog1.14599366
55MP0003136_yellow_coat_color1.13315431
56MP0009697_abnormal_copulation1.13255374
57MP0006036_abnormal_mitochondrial_physio1.11871261
58MP0002398_abnormal_bone_marrow1.08910517
59MP0002160_abnormal_reproductive_system1.08563375
60MP0003937_abnormal_limbs/digits/tail_de1.08177989
61MP0003121_genomic_imprinting1.07683773
62MP0002085_abnormal_embryonic_tissue1.04904066
63MP0001188_hyperpigmentation1.02587592
64MP0005389_reproductive_system_phenotype1.02478069
65MP0000689_abnormal_spleen_morphology1.02401741
66MP0008995_early_reproductive_senescence1.01835405
67MP0000358_abnormal_cell_content/1.01435925
68MP0002086_abnormal_extraembryonic_tissu1.00647624
69MP0001764_abnormal_homeostasis1.00041913
70MP0005671_abnormal_response_to0.99726308
71MP0002722_abnormal_immune_system0.99060782
72MP0000858_altered_metastatic_potential0.97713228
73MP0003567_abnormal_fetal_cardiomyocyte0.97513585
74MP0006035_abnormal_mitochondrial_morpho0.96253984
75MP0002254_reproductive_system_inflammat0.94546759
76MP0000703_abnormal_thymus_morphology0.92756981
77MP0001853_heart_inflammation0.91620997
78MP0002090_abnormal_vision0.91567224
79MP0002429_abnormal_blood_cell0.90492486
80MP0005253_abnormal_eye_physiology0.90013532
81MP0000647_abnormal_sebaceous_gland0.88439807
82MP0003646_muscle_fatigue0.88171110
83MP0002736_abnormal_nociception_after0.87847127
84MP0009785_altered_susceptibility_to0.87632702
85MP0002084_abnormal_developmental_patter0.87364608
86MP0004215_abnormal_myocardial_fiber0.85135487
87MP0002653_abnormal_ependyma_morphology0.85126297
88MP0009672_abnormal_birth_weight0.83804898
89MP0001835_abnormal_antigen_presentation0.83315148
90MP0005395_other_phenotype0.82937487
91MP0005408_hypopigmentation0.82533009
92MP0003941_abnormal_skin_development0.82488005
93MP0003950_abnormal_plasma_membrane0.81740810
94MP0002095_abnormal_skin_pigmentation0.81656502
95MP0005384_cellular_phenotype0.81179123
96MP0002234_abnormal_pharynx_morphology0.78973623
97MP0003656_abnormal_erythrocyte_physiolo0.77725814
98MP0002233_abnormal_nose_morphology0.76673727
99MP0003699_abnormal_female_reproductive0.76202212
100MP0003119_abnormal_digestive_system0.76072841
101MP0004197_abnormal_fetal_growth/weight/0.75279058
102MP0003221_abnormal_cardiomyocyte_apopto0.74384537
103MP0005621_abnormal_cell_physiology0.74196415
104MP0002837_dystrophic_cardiac_calcinosis0.73577733
105MP0000716_abnormal_immune_system0.73042421
106MP0005084_abnormal_gallbladder_morpholo0.72831726
107MP0005499_abnormal_olfactory_system0.72701779
108MP0005394_taste/olfaction_phenotype0.72701779
109MP0001986_abnormal_taste_sensitivity0.71769921
110MP0001919_abnormal_reproductive_system0.71587958
111MP0001286_abnormal_eye_development0.70985089
112MP0005266_abnormal_metabolism0.69123591
113MP0001727_abnormal_embryo_implantation0.67820615
114MP0002751_abnormal_autonomic_nervous0.67770576
115MP0001984_abnormal_olfaction0.66719947
116MP0010030_abnormal_orbit_morphology0.66498367
117MP0001324_abnormal_eye_pigmentation0.66051478
118MP0002111_abnormal_tail_morphology0.65638303
119MP0002420_abnormal_adaptive_immunity0.64579696
120MP0005332_abnormal_amino_acid0.63262159
121MP0005023_abnormal_wound_healing0.63168817
122MP0001819_abnormal_immune_cell0.63080957
123MP0002723_abnormal_immune_serum0.62180907
124MP0002161_abnormal_fertility/fecundity0.61198670
125MP0003698_abnormal_male_reproductive0.60929462
126MP0003448_altered_tumor_morphology0.60926097
127MP0000372_irregular_coat_pigmentation0.60359653
128MP0002452_abnormal_antigen_presenting0.60123125
129MP0002405_respiratory_system_inflammati0.59694036
130MP0008872_abnormal_physiological_respon0.59340264
131MP0000015_abnormal_ear_pigmentation0.57989428
132MP0005410_abnormal_fertilization0.57847036
133MP0001800_abnormal_humoral_immune0.57047618
134MP0001529_abnormal_vocalization0.56386312
135MP0005551_abnormal_eye_electrophysiolog0.55743896
136MP0002148_abnormal_hypersensitivity_rea0.54801116
137MP0001661_extended_life_span0.54076994
138MP0001293_anophthalmia0.53995324
139MP0000427_abnormal_hair_cycle0.53891399
140MP0000750_abnormal_muscle_regeneration0.53255751

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.46046667
2Breast hypoplasia (HP:0003187)4.59894096
3Carpal bone hypoplasia (HP:0001498)3.69397598
4Reticulocytopenia (HP:0001896)3.63843346
5Abnormality of cells of the erythroid lineage (HP:0012130)3.58020880
6Abnormal number of erythroid precursors (HP:0012131)3.53289644
7Degeneration of anterior horn cells (HP:0002398)3.49154188
8Abnormality of the anterior horn cell (HP:0006802)3.49154188
9Oral leukoplakia (HP:0002745)3.37761973
10Rough bone trabeculation (HP:0100670)3.36794615
11Chromsome breakage (HP:0040012)3.32160314
12Patellar aplasia (HP:0006443)3.26908043
13Aplastic anemia (HP:0001915)3.26124388
14Cerebral hypomyelination (HP:0006808)3.25703360
15Cerebral edema (HP:0002181)3.19085820
16Aplasia/Hypoplasia of the patella (HP:0006498)3.08563496
17Chromosomal breakage induced by crosslinking agents (HP:0003221)3.03527103
18Premature ovarian failure (HP:0008209)2.97865787
19Abnormality of methionine metabolism (HP:0010901)2.96315118
20Agnosia (HP:0010524)2.91805100
21Methylmalonic acidemia (HP:0002912)2.89928992
22Irregular epiphyses (HP:0010582)2.88203794
23Abnormality of the labia minora (HP:0012880)2.83362927
24Abnormality of the preputium (HP:0100587)2.80475176
25Renal Fanconi syndrome (HP:0001994)2.79650230
26Secondary amenorrhea (HP:0000869)2.77611603
27Macrocytic anemia (HP:0001972)2.75994065
28Acute necrotizing encephalopathy (HP:0006965)2.68161652
29Abnormality of the heme biosynthetic pathway (HP:0010472)2.66977166
3011 pairs of ribs (HP:0000878)2.63236456
31Increased CSF lactate (HP:0002490)2.62049168
32Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.61980062
33Meckel diverticulum (HP:0002245)2.61457385
34Abnormality of chromosome stability (HP:0003220)2.58616106
35Increased serum lactate (HP:0002151)2.58120196
36Abnormal trabecular bone morphology (HP:0100671)2.57568522
37Abnormal spermatogenesis (HP:0008669)2.52700397
38Abnormality of serum amino acid levels (HP:0003112)2.52179992
39Mitochondrial inheritance (HP:0001427)2.50121994
40Abnormality of the ileum (HP:0001549)2.50051156
41Abnormality of glycolysis (HP:0004366)2.49424121
42Increased serum pyruvate (HP:0003542)2.49424121
43Absent thumb (HP:0009777)2.48733081
44Pallor (HP:0000980)2.48722859
45Microretrognathia (HP:0000308)2.48039540
46Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.47714136
47Decreased activity of mitochondrial respiratory chain (HP:0008972)2.47714136
48Methylmalonic aciduria (HP:0012120)2.47210834
49Abnormal mitochondria in muscle tissue (HP:0008316)2.45942234
50Hepatocellular necrosis (HP:0001404)2.45477898
51Selective tooth agenesis (HP:0001592)2.45369310
52Colon cancer (HP:0003003)2.44722819
53Myelodysplasia (HP:0002863)2.43389575
543-Methylglutaconic aciduria (HP:0003535)2.43152364
55Abnormality of aspartate family amino acid metabolism (HP:0010899)2.43120955
56Hyperglycinemia (HP:0002154)2.39778232
57Absent radius (HP:0003974)2.37721596
58Type 2 muscle fiber atrophy (HP:0003554)2.36436619
59Abnormality of alanine metabolism (HP:0010916)2.35730542
60Hyperalaninemia (HP:0003348)2.35730542
61Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.35730542
62Leukodystrophy (HP:0002415)2.34062427
63Horseshoe kidney (HP:0000085)2.32191086
64Increased hepatocellular lipid droplets (HP:0006565)2.30904634
65Bone marrow hypocellularity (HP:0005528)2.29414283
66Respiratory failure (HP:0002878)2.28860208
67Impulsivity (HP:0100710)2.27798295
68Premature graying of hair (HP:0002216)2.26943459
69Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.26353732
70Glossoptosis (HP:0000162)2.25418773
71Muscle fiber atrophy (HP:0100295)2.23862808
72Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.21830851
73Hepatic necrosis (HP:0002605)2.21635010
74Absent forearm bone (HP:0003953)2.20594133
75Aplasia involving forearm bones (HP:0009822)2.20594133
76Cleft eyelid (HP:0000625)2.19943730
77Trismus (HP:0000211)2.19198608
78Abnormality of the duodenum (HP:0002246)2.19027454
79Increased intramyocellular lipid droplets (HP:0012240)2.17467169
80Reduced antithrombin III activity (HP:0001976)2.15343477
81Amaurosis fugax (HP:0100576)2.13061877
82Ependymoma (HP:0002888)2.12291635
83Pancytopenia (HP:0001876)2.11604739
84Aplasia/Hypoplasia of the uvula (HP:0010293)2.11500054
85Medulloblastoma (HP:0002885)2.11053742
86Small intestinal stenosis (HP:0012848)2.09809971
87Duodenal stenosis (HP:0100867)2.09809971
88CNS hypomyelination (HP:0003429)2.08443796
89Lethargy (HP:0001254)2.07171338
90Supernumerary spleens (HP:0009799)2.06744408
91Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.06480811
92Abnormal protein N-linked glycosylation (HP:0012347)2.06480811
93Abnormal protein glycosylation (HP:0012346)2.06480811
94Abnormal glycosylation (HP:0012345)2.06480811
95Hypoplasia of the capital femoral epiphysis (HP:0003090)2.06243923
96Neoplasm of the pancreas (HP:0002894)2.04547259
97Acute encephalopathy (HP:0006846)2.04540177
98Microvesicular hepatic steatosis (HP:0001414)2.02241573
99Multiple enchondromatosis (HP:0005701)2.00307461
100Neoplasm of the adrenal gland (HP:0100631)1.98954610
101Rhabdomyosarcoma (HP:0002859)1.98856644
102Sparse eyelashes (HP:0000653)1.98301602
103Atrophy/Degeneration involving motor neurons (HP:0007373)1.97511053
104Progressive macrocephaly (HP:0004481)1.96879011
105Respiratory difficulties (HP:0002880)1.96250028
106Cellular immunodeficiency (HP:0005374)1.95516930
107Exertional dyspnea (HP:0002875)1.95279367
108Azoospermia (HP:0000027)1.94895240
109Amniotic constriction ring (HP:0009775)1.94637026
110Abnormality of placental membranes (HP:0011409)1.94637026
111Lipid accumulation in hepatocytes (HP:0006561)1.91761389
112Type I transferrin isoform profile (HP:0003642)1.91589543
113Optic disc pallor (HP:0000543)1.90263592
114Sloping forehead (HP:0000340)1.89736444
115Exercise intolerance (HP:0003546)1.88243678
116Abnormality of the pons (HP:0007361)1.88159049
117Nephroblastoma (Wilms tumor) (HP:0002667)1.87803800
118Postnatal microcephaly (HP:0005484)1.87608106
119Lymphoma (HP:0002665)1.87358924
120Sensory axonal neuropathy (HP:0003390)1.85211415
121CNS demyelination (HP:0007305)1.84851610
122Megaloblastic anemia (HP:0001889)1.83378777
123Absent epiphyses (HP:0010577)1.83139283
124Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.83139283
125Lactic acidosis (HP:0003128)1.82886929
126Abnormal lung lobation (HP:0002101)1.82366677
127Facial cleft (HP:0002006)1.81486942
128Abnormality of sulfur amino acid metabolism (HP:0004339)1.80689727
129Aplasia/Hypoplasia of the fovea (HP:0008060)1.80585333
130Hypoplasia of the fovea (HP:0007750)1.80585333
131Embryonal renal neoplasm (HP:0011794)1.80324171
132Hypoplasia of the pons (HP:0012110)1.79901970
133Abnormality of homocysteine metabolism (HP:0010919)1.78730869
134Homocystinuria (HP:0002156)1.78730869
135Abnormality of the carotid arteries (HP:0005344)1.77410369
136Abnormality of serine family amino acid metabolism (HP:0010894)1.77280744
137Abnormality of glycine metabolism (HP:0010895)1.77280744
138Triphalangeal thumb (HP:0001199)1.76986684
139Median cleft lip (HP:0000161)1.76819760
140Abnormality of the vitamin B12 metabolism (HP:0004341)1.75399438
141Glioma (HP:0009733)1.74501249

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.87493424
2WEE14.37931018
3EIF2AK14.02261958
4VRK23.14058267
5CDC73.13947002
6TSSK63.06650439
7STK162.82846731
8SRPK12.80206489
9NME22.59697332
10TRIM282.51036578
11PLK42.41299291
12ACVR1B2.41296994
13EIF2AK32.36736354
14BRSK22.05782841
15TTK2.02093080
16NUAK11.97720691
17NEK11.94961715
18VRK11.94755393
19PLK31.94259252
20PLK11.90788576
21NEK21.85185631
22CCNB11.74215010
23TAF11.64166578
24PIM21.52415141
25MKNK11.47167261
26PBK1.46716054
27WNK31.44549607
28NME11.41093778
29AURKB1.37052397
30EPHA21.36447909
31MST41.33881710
32BMPR1B1.32717487
33RPS6KB21.31032027
34BRAF1.25944941
35ZAK1.25848280
36MKNK21.25842297
37RPS6KA41.21374497
38PNCK1.21035953
39AURKA1.19909166
40CDK71.17774798
41BRSK11.16126078
42AKT31.15500601
43ATR1.14530123
44TNIK1.12940140
45ARAF1.08329871
46MAP4K21.08319249
47EIF2AK21.07107767
48DYRK31.03799784
49CHEK21.01650183
50TLK11.00089600
51ERBB30.99531983
52BCR0.96894229
53CSNK1G10.94599328
54STK38L0.91283715
55BMPR20.91170704
56TESK20.90657988
57MAP3K120.87875810
58PDK40.87210074
59PDK30.87210074
60MAP3K80.85879344
61PIM10.85590830
62PDK20.85395213
63CSNK1G30.83582246
64CHEK10.82693077
65CDK80.82607552
66PASK0.81352318
67MAP3K30.80148309
68TXK0.79893566
69ALK0.77214449
70FRK0.76645589
71STK100.75634057
72MAPKAPK30.74381662
73OXSR10.70753853
74CSNK1G20.70613813
75CSNK2A10.70540637
76CSNK2A20.70040426
77FLT30.66355095
78PAK40.65132102
79RAF10.65049714
80BCKDK0.64857052
81PRKCI0.61164851
82CSNK1A1L0.60925612
83STK240.58738845
84IRAK30.58507754
85MAP2K30.58347832
86MOS0.58288788
87SCYL20.58140433
88PAK10.57633438
89GRK10.56622901
90MAP3K110.55762613
91CSNK1E0.55670108
92ATM0.55176220
93STK390.55145572
94IRAK40.53644444
95ABL20.52677485
96TGFBR10.51803499
97CDK40.51258815
98PLK20.51226238
99CLK10.49333019
100KDR0.48970297
101CDK20.48565217
102ERBB40.48281030
103ZAP700.45812745
104TAOK20.43844911
105MAP3K50.43618639
106TEC0.43342822
107FGFR10.42930923
108ADRBK20.42521831
109DYRK20.41350809
110MAP4K10.40382414
111STK40.39699206
112MAP3K60.38747105
113IKBKB0.37988684
114MAP3K40.37194938
115* CDK10.35294489
116CDK30.33472257
117DAPK10.31739259
118LATS20.30897768
119MAPKAPK50.30896352
120MARK30.30084081
121RPS6KA50.29912944
122MAP2K70.29821282
123TESK10.29636607
124NEK90.28098598
125PRKDC0.26756185
126WNK40.26029382
127STK30.25400093
128MINK10.25377475
129MELK0.24952623
130LIMK10.23311453
131CSNK1A10.21395660
132CDK90.20338714
133PRKCG0.19823867
134INSRR0.19478010
135LYN0.19326445
136YES10.19161441
137PRKACB0.17884234

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.66516120
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.14288836
3RNA polymerase_Homo sapiens_hsa030204.12334814
4DNA replication_Homo sapiens_hsa030304.08072276
5Mismatch repair_Homo sapiens_hsa034303.57891213
6Ribosome_Homo sapiens_hsa030103.46192521
7RNA transport_Homo sapiens_hsa030133.04938328
8Spliceosome_Homo sapiens_hsa030402.98541113
9Homologous recombination_Homo sapiens_hsa034402.87373116
10Nucleotide excision repair_Homo sapiens_hsa034202.64802735
11Pyrimidine metabolism_Homo sapiens_hsa002402.62462167
12Base excision repair_Homo sapiens_hsa034102.59493700
13Basal transcription factors_Homo sapiens_hsa030222.39369671
14Cell cycle_Homo sapiens_hsa041102.31798486
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.25239065
16RNA degradation_Homo sapiens_hsa030182.05567555
17One carbon pool by folate_Homo sapiens_hsa006702.02770187
18Fanconi anemia pathway_Homo sapiens_hsa034601.91918953
19Non-homologous end-joining_Homo sapiens_hsa034501.82774429
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.65277204
21Vitamin B6 metabolism_Homo sapiens_hsa007501.62449543
22Propanoate metabolism_Homo sapiens_hsa006401.61451546
23Purine metabolism_Homo sapiens_hsa002301.56119029
24p53 signaling pathway_Homo sapiens_hsa041151.46897513
25mRNA surveillance pathway_Homo sapiens_hsa030151.40428764
26Oxidative phosphorylation_Homo sapiens_hsa001901.35258569
27Epstein-Barr virus infection_Homo sapiens_hsa051691.34461897
28Huntingtons disease_Homo sapiens_hsa050161.24146829
29Parkinsons disease_Homo sapiens_hsa050121.23603106
30Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.20953455
31Protein export_Homo sapiens_hsa030601.17600370
32Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.16205483
33Fatty acid elongation_Homo sapiens_hsa000621.09721956
34Steroid biosynthesis_Homo sapiens_hsa001001.05149185
35Antigen processing and presentation_Homo sapiens_hsa046121.04139820
36Folate biosynthesis_Homo sapiens_hsa007901.03965626
37Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.03815682
38Oocyte meiosis_Homo sapiens_hsa041140.92597617
39Cysteine and methionine metabolism_Homo sapiens_hsa002700.90254178
40Herpes simplex infection_Homo sapiens_hsa051680.85486136
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.84054009
42Drug metabolism - other enzymes_Homo sapiens_hsa009830.82233265
43Pentose phosphate pathway_Homo sapiens_hsa000300.77784757
44Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.77130436
45Sulfur metabolism_Homo sapiens_hsa009200.76853863
46Legionellosis_Homo sapiens_hsa051340.76659982
47Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.74693409
48Regulation of autophagy_Homo sapiens_hsa041400.72689787
49Biosynthesis of amino acids_Homo sapiens_hsa012300.71993218
50Graft-versus-host disease_Homo sapiens_hsa053320.71550241
51Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.69706350
52Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.67141921
53Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.66021313
54Systemic lupus erythematosus_Homo sapiens_hsa053220.64405093
55Cardiac muscle contraction_Homo sapiens_hsa042600.61991652
56Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.57509662
57Thyroid cancer_Homo sapiens_hsa052160.55400276
58Cyanoamino acid metabolism_Homo sapiens_hsa004600.55227786
59Viral carcinogenesis_Homo sapiens_hsa052030.54552865
60Caffeine metabolism_Homo sapiens_hsa002320.53573401
61Glutathione metabolism_Homo sapiens_hsa004800.52772692
62Pentose and glucuronate interconversions_Homo sapiens_hsa000400.51627635
63Sulfur relay system_Homo sapiens_hsa041220.50275261
64Peroxisome_Homo sapiens_hsa041460.50119700
65Alzheimers disease_Homo sapiens_hsa050100.50098599
66Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.47226479
67Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.46358462
68NOD-like receptor signaling pathway_Homo sapiens_hsa046210.43734441
69Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.43682340
70Fatty acid metabolism_Homo sapiens_hsa012120.43124473
71N-Glycan biosynthesis_Homo sapiens_hsa005100.42670745
72Fructose and mannose metabolism_Homo sapiens_hsa000510.42511523
73Carbon metabolism_Homo sapiens_hsa012000.42493720
74Butanoate metabolism_Homo sapiens_hsa006500.42155120
75Allograft rejection_Homo sapiens_hsa053300.41486055
76Selenocompound metabolism_Homo sapiens_hsa004500.40928200
77Metabolic pathways_Homo sapiens_hsa011000.39330699
78HTLV-I infection_Homo sapiens_hsa051660.38857431
79Collecting duct acid secretion_Homo sapiens_hsa049660.38590743
80Fatty acid degradation_Homo sapiens_hsa000710.37476591
81Primary immunodeficiency_Homo sapiens_hsa053400.37353113
82Measles_Homo sapiens_hsa051620.37322659
83Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.37076606
84NF-kappa B signaling pathway_Homo sapiens_hsa040640.36306450
85beta-Alanine metabolism_Homo sapiens_hsa004100.35216908
86Apoptosis_Homo sapiens_hsa042100.33990514
87Tryptophan metabolism_Homo sapiens_hsa003800.33650897
88Type I diabetes mellitus_Homo sapiens_hsa049400.33405097
89Rheumatoid arthritis_Homo sapiens_hsa053230.33268351
90Shigellosis_Homo sapiens_hsa051310.32476906
91Arachidonic acid metabolism_Homo sapiens_hsa005900.31065174
92Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.30004385
93Hematopoietic cell lineage_Homo sapiens_hsa046400.29626088
94Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.29486620
95Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.29395527
96Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.28575726
97Influenza A_Homo sapiens_hsa051640.28194420
98Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.26600446
99RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.26568490
100Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.22070272
101Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.21874256
1022-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.21733537
103Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.19846666
104SNARE interactions in vesicular transport_Homo sapiens_hsa041300.19775941
105Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.19437153
106Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.17813922
107Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.17055685
108Vitamin digestion and absorption_Homo sapiens_hsa049770.16648095
109Primary bile acid biosynthesis_Homo sapiens_hsa001200.16336348
110Galactose metabolism_Homo sapiens_hsa000520.16024523
111Hepatitis B_Homo sapiens_hsa051610.14855167
112Nitrogen metabolism_Homo sapiens_hsa009100.14543991
113Maturity onset diabetes of the young_Homo sapiens_hsa049500.13647046
114Phototransduction_Homo sapiens_hsa047440.13267508
115Phagosome_Homo sapiens_hsa041450.13052637
116Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.13012425
117Retinol metabolism_Homo sapiens_hsa008300.12580559
118Pyruvate metabolism_Homo sapiens_hsa006200.12494182
119Chemical carcinogenesis_Homo sapiens_hsa052040.12096827
120HIF-1 signaling pathway_Homo sapiens_hsa040660.11954042
121Asthma_Homo sapiens_hsa053100.11953229
122Tyrosine metabolism_Homo sapiens_hsa003500.11859960
123TGF-beta signaling pathway_Homo sapiens_hsa043500.11158516
124Intestinal immune network for IgA production_Homo sapiens_hsa046720.10910439
125Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.10210528
126Transcriptional misregulation in cancer_Homo sapiens_hsa052020.08533534
127Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.08347241
128Circadian rhythm_Homo sapiens_hsa047100.06600112
129Small cell lung cancer_Homo sapiens_hsa052220.06018830
130Vibrio cholerae infection_Homo sapiens_hsa051100.05906877
131Alcoholism_Homo sapiens_hsa050340.05219235
132Arginine and proline metabolism_Homo sapiens_hsa003300.04955094
133Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.03938754
134Hippo signaling pathway_Homo sapiens_hsa043900.02400823

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »