OST4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)7.44995959
2ribosomal small subunit biogenesis (GO:0042274)7.31987180
3translational termination (GO:0006415)7.14221083
4SRP-dependent cotranslational protein targeting to membrane (GO:0006614)7.06549667
5ribosomal small subunit assembly (GO:0000028)7.04474009
6cotranslational protein targeting to membrane (GO:0006613)7.03060744
7protein targeting to ER (GO:0045047)6.97568486
8establishment of protein localization to endoplasmic reticulum (GO:0072599)6.65052530
9protein localization to endoplasmic reticulum (GO:0070972)6.62897442
10translational elongation (GO:0006414)5.90004634
11sequestering of actin monomers (GO:0042989)5.75219902
12viral life cycle (GO:0019058)5.64664557
13cellular protein complex disassembly (GO:0043624)5.48080064
14mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.28695581
15nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.12185629
16translational initiation (GO:0006413)5.07772158
17maturation of SSU-rRNA (GO:0030490)5.04391972
18energy coupled proton transport, down electrochemical gradient (GO:0015985)4.93475334
19ATP synthesis coupled proton transport (GO:0015986)4.93475334
20translation (GO:0006412)4.69665906
21ribosomal large subunit biogenesis (GO:0042273)4.68361843
22protein targeting to membrane (GO:0006612)4.66682922
23thrombin receptor signaling pathway (GO:0070493)4.60320062
24mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.52744878
25proteasome assembly (GO:0043248)4.52203743
26protein complex disassembly (GO:0043241)4.51601874
27signal peptide processing (GO:0006465)4.47883474
28protein neddylation (GO:0045116)4.34015016
29macromolecular complex disassembly (GO:0032984)4.25120054
30DNA deamination (GO:0045006)4.23004948
31ATP biosynthetic process (GO:0006754)4.16326711
32platelet dense granule organization (GO:0060155)4.10330786
33respiratory electron transport chain (GO:0022904)4.09911274
34GTP biosynthetic process (GO:0006183)4.04607166
35electron transport chain (GO:0022900)3.99821164
36hydrogen ion transmembrane transport (GO:1902600)3.94041284
37purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.78774263
38purine nucleoside triphosphate biosynthetic process (GO:0009145)3.77355355
39termination of RNA polymerase III transcription (GO:0006386)3.77005395
40transcription elongation from RNA polymerase III promoter (GO:0006385)3.77005395
41nuclear-transcribed mRNA catabolic process (GO:0000956)3.65503602
42pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.58014761
43proton transport (GO:0015992)3.57519193
44blood coagulation, intrinsic pathway (GO:0007597)3.52218773
45mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.51404848
46mitochondrial respiratory chain complex I assembly (GO:0032981)3.51404848
47NADH dehydrogenase complex assembly (GO:0010257)3.51404848
48antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.51283991
49hydrogen transport (GO:0006818)3.50180023
50protein complex biogenesis (GO:0070271)3.49057961
51ribonucleoprotein complex biogenesis (GO:0022613)3.47719325
52mRNA catabolic process (GO:0006402)3.47017107
53UTP biosynthetic process (GO:0006228)3.46985581
54inner mitochondrial membrane organization (GO:0007007)3.43019271
55pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.40320850
56antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.37389974
57negative regulation of appetite (GO:0032099)3.35160345
58negative regulation of response to food (GO:0032096)3.35160345
59L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.34336505
60lipoxygenase pathway (GO:0019372)3.25719783
61establishment of protein localization to membrane (GO:0090150)3.24613930
62autophagic vacuole fusion (GO:0000046)3.22057250
63negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.21931197
64angiogenesis involved in wound healing (GO:0060055)3.21036570
65negative regulation of heart rate (GO:0010459)3.20039542
66cellular component biogenesis (GO:0044085)3.19179814
67ribonucleoside triphosphate biosynthetic process (GO:0009201)3.14325578
68peptidyl-histidine modification (GO:0018202)3.13480050
69triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.13350523
70mitochondrial respiratory chain complex assembly (GO:0033108)3.12202832
71protein targeting (GO:0006605)3.12024940
72positive regulation of endothelial cell differentiation (GO:0045603)3.11404951
73regulation of integrin-mediated signaling pathway (GO:2001044)3.10838073
74RNA catabolic process (GO:0006401)3.10698360
75mitochondrial calcium ion transport (GO:0006851)3.10396233
76guanosine-containing compound biosynthetic process (GO:1901070)3.09839552
77regulation of cellular amino acid metabolic process (GO:0006521)3.07289902
78chaperone-mediated protein transport (GO:0072321)3.05268012
79CTP metabolic process (GO:0046036)3.03022296
80CTP biosynthetic process (GO:0006241)3.03022296
81negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)3.02101978
82UTP metabolic process (GO:0046051)3.01583420
83regulation of platelet activation (GO:0010543)3.00763676
84DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.00150909
85negative regulation of ligase activity (GO:0051352)2.99340161
86negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.99340161
87erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.93402701
88L-phenylalanine catabolic process (GO:0006559)2.93402701
89nucleoside triphosphate biosynthetic process (GO:0009142)2.92727620
90positive regulation of mast cell activation (GO:0033005)2.92447342
91mitochondrial transport (GO:0006839)2.92067190
92regulation of platelet aggregation (GO:0090330)2.90826844
93intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.90735165
94signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.90735165
95rRNA processing (GO:0006364)2.90664212
96positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.89583465
97regulation of lipoprotein metabolic process (GO:0050746)2.89453808
98signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.89401573
99signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.89401573
100signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.89401573
101respiratory chain complex IV assembly (GO:0008535)2.88664124
102positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.88551463
1037-methylguanosine mRNA capping (GO:0006370)2.85734400
104antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.85509653
105oxidative phosphorylation (GO:0006119)2.85164912
106nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.84808096
107establishment of protein localization to mitochondrial membrane (GO:0090151)2.84773044
108RNA capping (GO:0036260)2.84322484
1097-methylguanosine RNA capping (GO:0009452)2.84322484
110establishment of protein localization to organelle (GO:0072594)2.83140058
111protein targeting to mitochondrion (GO:0006626)2.82564181
112exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.82226373
113negative regulation of norepinephrine secretion (GO:0010700)2.80050671
114regulation of oxidative phosphorylation (GO:0002082)2.78743780
115polyamine biosynthetic process (GO:0006596)2.78273390
116positive regulation of protein homodimerization activity (GO:0090073)2.77606022
117rRNA modification (GO:0000154)2.77105262
118negative regulation of platelet activation (GO:0010544)2.76779227
119signal transduction involved in DNA integrity checkpoint (GO:0072401)2.76302819
120signal transduction involved in DNA damage checkpoint (GO:0072422)2.76302819
121regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.76064530
122pyrimidine nucleotide catabolic process (GO:0006244)2.75872757
123rRNA metabolic process (GO:0016072)2.75687332
124regulation of metalloenzyme activity (GO:0048552)2.74800047
125innate immune response in mucosa (GO:0002227)2.74472129
126purine-containing compound salvage (GO:0043101)2.72694704
127regulation of mitochondrial translation (GO:0070129)2.72677634
128deoxyribonucleotide catabolic process (GO:0009264)2.72484445
129G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.72030455
130establishment of protein localization to mitochondrion (GO:0072655)2.71142226
131signal transduction involved in cell cycle checkpoint (GO:0072395)2.71102126
132platelet aggregation (GO:0070527)2.69462304
133pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.68994207
134establishment of integrated proviral latency (GO:0075713)2.68524698
135establishment of viral latency (GO:0019043)2.68352175
136pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.67538791
137leukocyte migration involved in inflammatory response (GO:0002523)2.66583159
138dopamine transport (GO:0015872)2.65718440
139purinergic nucleotide receptor signaling pathway (GO:0035590)2.65163555
140protein localization to mitochondrion (GO:0070585)2.64306703
141mannosylation (GO:0097502)2.61845115
142anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.61207316
143response to interferon-beta (GO:0035456)2.60858232
144GPI anchor biosynthetic process (GO:0006506)2.58955482
145cytochrome complex assembly (GO:0017004)2.58413347
146pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.58346707
147deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.58210594
148L-methionine biosynthetic process (GO:0071265)2.56599085
149amino acid salvage (GO:0043102)2.56599085
150L-methionine salvage (GO:0071267)2.56599085
151neutrophil activation involved in immune response (GO:0002283)2.54785300

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.67662743
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.69954249
3GABP_17652178_ChIP-ChIP_JURKAT_Human4.51235659
4EST1_17652178_ChIP-ChIP_JURKAT_Human4.03170791
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.79631813
6CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.62585440
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.41359422
8CREB1_15753290_ChIP-ChIP_HEK293T_Human3.36727725
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.27096754
10EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.20858266
11NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.17415743
12CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.13917389
13ELF1_17652178_ChIP-ChIP_JURKAT_Human2.92068114
14HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.76525500
15MYC_18358816_ChIP-ChIP_MESCs_Mouse2.61759825
16ELK1_19687146_ChIP-ChIP_HELA_Human2.54380788
17* VDR_23849224_ChIP-Seq_CD4+_Human2.42561167
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.41195291
19BP1_19119308_ChIP-ChIP_Hs578T_Human2.40286860
20MYC_19079543_ChIP-ChIP_MESCs_Mouse2.33733302
21SRF_21415370_ChIP-Seq_HL-1_Mouse2.31065421
22MYC_19030024_ChIP-ChIP_MESCs_Mouse2.30942893
23DCP1A_22483619_ChIP-Seq_HELA_Human2.29166164
24HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.28905032
25XRN2_22483619_ChIP-Seq_HELA_Human2.21260303
26PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.21172560
27CEBPB_24764292_ChIP-Seq_MC3T3_Mouse2.20898021
28E2F1_18555785_ChIP-Seq_MESCs_Mouse2.18407087
29ELK1_22589737_ChIP-Seq_MCF10A_Human2.10897211
30SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.04815801
31TTF2_22483619_ChIP-Seq_HELA_Human1.97200476
32E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.89237576
33HOXB4_20404135_ChIP-ChIP_EML_Mouse1.87291898
34HTT_18923047_ChIP-ChIP_STHdh_Human1.83636283
35FOXP3_21729870_ChIP-Seq_TREG_Human1.81578096
36TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.78021981
37NELFA_20434984_ChIP-Seq_ESCs_Mouse1.77672206
38SRY_22984422_ChIP-ChIP_TESTIS_Rat1.77185839
39TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.76516636
40FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.71614833
41EZH2_22144423_ChIP-Seq_EOC_Human1.70197217
42* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.69822210
43FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.66391622
44TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.62405966
45VDR_22108803_ChIP-Seq_LS180_Human1.62397891
46ERG_20887958_ChIP-Seq_HPC-7_Mouse1.61644327
47RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.60365206
48TRIM28_21343339_ChIP-Seq_HEK293_Human1.60216803
49SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.59440149
50FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.55627500
51GABP_19822575_ChIP-Seq_HepG2_Human1.54313906
52EWS_26573619_Chip-Seq_HEK293_Human1.52475492
53IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.52260400
54SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.51850239
55TP63_17297297_ChIP-ChIP_HaCaT_Human1.51162595
56EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.45347373
57IRF8_22096565_ChIP-ChIP_GC-B_Human1.43699637
58LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.43533772
59THAP11_20581084_ChIP-Seq_MESCs_Mouse1.43057393
60ERG_20517297_ChIP-Seq_VCAP_Human1.42214610
61AR_20517297_ChIP-Seq_VCAP_Human1.41192949
62MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.38021828
63IRF8_21731497_ChIP-ChIP_J774_Mouse1.37021122
64ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.36559385
65E2F4_17652178_ChIP-ChIP_JURKAT_Human1.33691487
66YY1_21170310_ChIP-Seq_MESCs_Mouse1.30500941
67FLI1_27457419_Chip-Seq_LIVER_Mouse1.29895646
68PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.28750699
69SPI1_23547873_ChIP-Seq_NB4_Human1.27984140
70NOTCH1_21737748_ChIP-Seq_TLL_Human1.27660217
71DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.22048600
72ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.19597016
73E2F7_22180533_ChIP-Seq_HELA_Human1.19044731
74* NANOG_20526341_ChIP-Seq_ESCs_Human1.18751366
75CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.18224940
76EGR1_23403033_ChIP-Seq_LIVER_Mouse1.16368253
77FOXA1_25329375_ChIP-Seq_VCAP_Human1.16090914
78FOXA1_27270436_Chip-Seq_PROSTATE_Human1.16090914
79* GATA3_21878914_ChIP-Seq_MCF-7_Human1.15802114
80NANOG_19829295_ChIP-Seq_ESCs_Human1.15337711
81SOX2_19829295_ChIP-Seq_ESCs_Human1.15337711
82GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14916029
83SALL4_22934838_ChIP-ChIP_CD34+_Human1.14717160
84GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.14273046
85TP53_22573176_ChIP-Seq_HFKS_Human1.13785390
86KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.12464493
87HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.11725234
88MYC_18940864_ChIP-ChIP_HL60_Human1.11658432
89HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.10760948
90CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.09686196
91STAT4_19710469_ChIP-ChIP_TH1__Mouse1.09548319
92SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.08800212
93STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.06989343
94SOX17_20123909_ChIP-Seq_XEN_Mouse1.06057863
95POU5F1_16153702_ChIP-ChIP_HESCs_Human1.05672082
96BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.03434479
97MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.01333625
98SCL_19346495_ChIP-Seq_HPC-7_Human1.01057564
99PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.00957862
100NANOG_18555785_ChIP-Seq_MESCs_Mouse1.00462640
101POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.00245936
102IKZF1_21737484_ChIP-ChIP_HCT116_Human0.97872941
103ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.95396963
104MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.93553368
105SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.92948725
106SOX2_16153702_ChIP-ChIP_HESCs_Human0.92544284
107PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.91592785
108ZFX_18555785_ChIP-Seq_MESCs_Mouse0.90341380
109PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.88837929
110PADI4_21655091_ChIP-ChIP_MCF-7_Human0.87860850
111POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.87685265
112NANOG_16153702_ChIP-ChIP_HESCs_Human0.87040100
113MYCN_18555785_ChIP-Seq_MESCs_Mouse0.86318184
114SOX2_22085726_ChIP-Seq_NPCs_Mouse0.86003898
115EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.85568008
116MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.85009744
117CTCF_18555785_ChIP-Seq_MESCs_Mouse0.82823010
118RBPJ_21746931_ChIP-Seq_IB4_Human0.82543663
119KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.82319290
120KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.82319290
121KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.82319290
122IRF1_19129219_ChIP-ChIP_H3396_Human0.81420146
123SPI1_20517297_ChIP-Seq_HL60_Human0.80883503
124TAF2_19829295_ChIP-Seq_ESCs_Human0.79521108
125RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.78855534
126CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.78353467
127CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.78212055
128CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.77879287
129GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.77450634
130STAT1_20625510_ChIP-Seq_HELA_Human0.77244626
131TFEB_21752829_ChIP-Seq_HELA_Human0.75688516
132FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.74747880
133MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.74593636
134CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.74311150
135PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.74036124
136LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.73415445
137RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.71365999
138SOX2_18692474_ChIP-Seq_MEFs_Mouse0.70010133

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005464_abnormal_platelet_physiology6.28950251
2MP0009379_abnormal_foot_pigmentation5.68677588
3MP0008004_abnormal_stomach_pH4.09585885
4MP0003724_increased_susceptibility_to3.35372594
5MP0003186_abnormal_redox_activity2.86555899
6MP0003136_yellow_coat_color2.64777298
7MP0008438_abnormal_cutaneous_collagen2.40946883
8MP0002736_abnormal_nociception_after2.37106549
9MP0002148_abnormal_hypersensitivity_rea2.20770966
10MP0004381_abnormal_hair_follicle2.03304199
11MP0003693_abnormal_embryo_hatching2.02788183
12MP0005503_abnormal_tendon_morphology1.98464195
13MP0004510_myositis1.98251825
14MP0004142_abnormal_muscle_tone1.98021236
15MP0002163_abnormal_gland_morphology1.96996203
16MP0001542_abnormal_bone_strength1.94513395
17MP0002933_joint_inflammation1.88151660
18MP0005379_endocrine/exocrine_gland_phen1.87973249
19MP0005408_hypopigmentation1.87365163
20MP0000372_irregular_coat_pigmentation1.86555493
21MP0002938_white_spotting1.83186180
22MP0003638_abnormal_response/metabolism_1.82523960
23MP0008872_abnormal_physiological_respon1.81249424
24MP0002132_abnormal_respiratory_system1.77416853
25MP0009785_altered_susceptibility_to1.72956015
26MP0001986_abnormal_taste_sensitivity1.69648949
27MP0008932_abnormal_embryonic_tissue1.68478783
28MP0001835_abnormal_antigen_presentation1.68410271
29MP0004957_abnormal_blastocyst_morpholog1.67954130
30MP0009333_abnormal_splenocyte_physiolog1.66858483
31MP0003436_decreased_susceptibility_to1.62086661
32MP0000230_abnormal_systemic_arterial1.61400666
33MP0006054_spinal_hemorrhage1.55826594
34MP0005083_abnormal_biliary_tract1.55311448
35MP0005000_abnormal_immune_tolerance1.54421131
36MP0003941_abnormal_skin_development1.48110486
37MP0004084_abnormal_cardiac_muscle1.46599507
38MP0005410_abnormal_fertilization1.46592655
39MP0005084_abnormal_gallbladder_morpholo1.43218311
40MP0005671_abnormal_response_to1.40964396
41MP0001533_abnormal_skeleton_physiology1.38848786
42MP0005025_abnormal_response_to1.38606677
43MP0003011_delayed_dark_adaptation1.34424263
44MP0004147_increased_porphyrin_level1.31561641
45MP0000343_altered_response_to1.29782826
46MP0001968_abnormal_touch/_nociception1.29215592
47MP0005646_abnormal_pituitary_gland1.28745611
48MP0002419_abnormal_innate_immunity1.28108459
49MP0003786_premature_aging1.27753004
50MP0006082_CNS_inflammation1.26920859
51MP0009250_abnormal_appendicular_skeleto1.26726771
52MP0003195_calcinosis1.23655814
53MP0008775_abnormal_heart_ventricle1.23306523
54MP0005390_skeleton_phenotype1.22699342
55MP0005275_abnormal_skin_tensile1.22125098
56MP0006292_abnormal_olfactory_placode1.17747689
57MP0001663_abnormal_digestive_system1.17438556
58MP0009764_decreased_sensitivity_to1.17086743
59MP0001853_heart_inflammation1.15757015
60MP0006035_abnormal_mitochondrial_morpho1.14450501
61MP0002638_abnormal_pupillary_reflex1.12418797
62MP0008875_abnormal_xenobiotic_pharmacok1.12093647
63MP0002837_dystrophic_cardiac_calcinosis1.11032688
64MP0002277_abnormal_respiratory_mucosa1.10120655
65MP0005409_darkened_coat_color1.09668564
66MP0003718_maternal_effect1.08832080
67MP0000685_abnormal_immune_system1.08255829
68MP0005365_abnormal_bile_salt1.07322737
69MP0002723_abnormal_immune_serum1.06046220
70MP0003656_abnormal_erythrocyte_physiolo1.06028833
71MP0002405_respiratory_system_inflammati1.05890066
72MP0005164_abnormal_response_to1.05556591
73MP0000613_abnormal_salivary_gland1.05183133
74MP0005085_abnormal_gallbladder_physiolo1.03874455
75MP0005075_abnormal_melanosome_morpholog1.03536396
76MP0001879_abnormal_lymphatic_vessel1.03502047
77MP0003806_abnormal_nucleotide_metabolis1.03144642
78MP0002295_abnormal_pulmonary_circulatio1.03080673
79MP0005508_abnormal_skeleton_morphology1.02225757
80MP0002452_abnormal_antigen_presenting1.01990118
81MP0001529_abnormal_vocalization1.01346780
82MP0000762_abnormal_tongue_morphology1.01068834
83MP0002653_abnormal_ependyma_morphology1.01044131
84MP0005387_immune_system_phenotype1.00629813
85MP0001790_abnormal_immune_system1.00629813
86MP0005636_abnormal_mineral_homeostasis0.99241126
87MP0010386_abnormal_urinary_bladder0.98615754
88MP0006276_abnormal_autonomic_nervous0.98099717
89MP0009763_increased_sensitivity_to0.97029998
90MP0008995_early_reproductive_senescence0.96977723
91MP0001905_abnormal_dopamine_level0.96750680
92MP0000858_altered_metastatic_potential0.96567211
93MP0003828_pulmonary_edema0.96517102
94MP0004883_abnormal_blood_vessel0.96334175
95MP0005171_absent_coat_pigmentation0.95838391
96MP0002282_abnormal_trachea_morphology0.95741906
97MP0001346_abnormal_lacrimal_gland0.94373702
98MP0010329_abnormal_lipoprotein_level0.94364050
99MP0003279_aneurysm0.93795469
100MP0002234_abnormal_pharynx_morphology0.93696167
101MP0001756_abnormal_urination0.93633255
102MP0008007_abnormal_cellular_replicative0.93119234
103MP0002420_abnormal_adaptive_immunity0.91333223
104MP0000049_abnormal_middle_ear0.90938369
105MP0001819_abnormal_immune_cell0.90608133
106MP0006036_abnormal_mitochondrial_physio0.90550704
107MP0002733_abnormal_thermal_nociception0.89816586
108MP0004272_abnormal_basement_membrane0.89809681
109MP0005167_abnormal_blood-brain_barrier0.89162777
110MP0008469_abnormal_protein_level0.87757284
111MP0000249_abnormal_blood_vessel0.86937803
112MP0002095_abnormal_skin_pigmentation0.86322242
113MP0001845_abnormal_inflammatory_respons0.84218529
114MP0001800_abnormal_humoral_immune0.84054894
115MP0004036_abnormal_muscle_relaxation0.83871942
116MP0000163_abnormal_cartilage_morphology0.83334823
117MP0001243_abnormal_dermal_layer0.82990895
118MP0001727_abnormal_embryo_implantation0.82650931
119MP0005645_abnormal_hypothalamus_physiol0.81810912
120MP0005058_abnormal_lysosome_morphology0.81485203
121MP0005551_abnormal_eye_electrophysiolog0.79680726
122MP0003795_abnormal_bone_structure0.79572711
123MP0001919_abnormal_reproductive_system0.79127696
124MP0005174_abnormal_tail_pigmentation0.78621681
125MP0005381_digestive/alimentary_phenotyp0.78612799
126MP0002098_abnormal_vibrissa_morphology0.78448199
127MP0010155_abnormal_intestine_physiology0.77346573
128MP0000490_abnormal_crypts_of0.77079389
129MP0009642_abnormal_blood_homeostasis0.76946668
130MP0002006_tumorigenesis0.76713805
131MP0002102_abnormal_ear_morphology0.76498257
132MP0002009_preneoplasia0.75463979
133MP0008057_abnormal_DNA_replication0.75433328
134MP0001851_eye_inflammation0.74976519
135MP0002060_abnormal_skin_morphology0.74329741
136MP0000681_abnormal_thyroid_gland0.74082892
137MP0000920_abnormal_myelination0.73951046
138MP0009697_abnormal_copulation0.73390604
139MP0005165_increased_susceptibility_to0.72618383
140MP0004134_abnormal_chest_morphology0.72522120
141MP0003077_abnormal_cell_cycle0.71934331
142MP0001970_abnormal_pain_threshold0.71543151
143MP0002398_abnormal_bone_marrow0.71349866
144MP0004019_abnormal_vitamin_homeostasis0.71008310
145MP0009765_abnormal_xenobiotic_induced0.70838487
146MP0000465_gastrointestinal_hemorrhage0.69367002
147MP0010030_abnormal_orbit_morphology0.68694164
148MP0008789_abnormal_olfactory_epithelium0.68549342
149MP0000358_abnormal_cell_content/0.66676823
150MP0001764_abnormal_homeostasis0.65957355
151MP0006072_abnormal_retinal_apoptosis0.65777138
152MP0001293_anophthalmia0.65179959
153MP0004215_abnormal_myocardial_fiber0.61508544
154MP0002429_abnormal_blood_cell0.60887363

Predicted human phenotypes

RankGene SetZ-score
1Prolonged bleeding time (HP:0003010)6.19954664
2Menorrhagia (HP:0000132)5.89385196
3Abnormality of cells of the erythroid lineage (HP:0012130)5.47410600
4Increased mean platelet volume (HP:0011877)5.37376063
5Abnormal number of erythroid precursors (HP:0012131)5.13605856
6Abnormal platelet volume (HP:0011876)4.99074809
7Reticulocytopenia (HP:0001896)4.97163693
8Acute necrotizing encephalopathy (HP:0006965)4.50713011
9Mitochondrial inheritance (HP:0001427)4.46146685
10Increased hepatocellular lipid droplets (HP:0006565)4.37996681
11Macrocytic anemia (HP:0001972)4.15054891
12Epistaxis (HP:0000421)4.14157658
13Renal Fanconi syndrome (HP:0001994)3.97362581
14Lipid accumulation in hepatocytes (HP:0006561)3.92734668
15Abnormal mitochondria in muscle tissue (HP:0008316)3.88507652
16Gingival bleeding (HP:0000225)3.88144820
17Hepatocellular necrosis (HP:0001404)3.79512491
18Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.73381971
19Exertional dyspnea (HP:0002875)3.62136701
20Increased CSF lactate (HP:0002490)3.56296104
21Hepatic necrosis (HP:0002605)3.56237121
22Progressive macrocephaly (HP:0004481)3.56010315
23Acute encephalopathy (HP:0006846)3.52633206
24Pallor (HP:0000980)3.51341044
25Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.50999084
26Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.44374026
273-Methylglutaconic aciduria (HP:0003535)3.40636566
28Aplasia/Hypoplasia of the sacrum (HP:0008517)3.39615018
29Impaired platelet aggregation (HP:0003540)3.21376949
30Abnormal platelet function (HP:0011869)3.21376949
31Decreased activity of mitochondrial respiratory chain (HP:0008972)3.20955692
32Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.20955692
33Hyperlipoproteinemia (HP:0010980)3.19408163
34Parakeratosis (HP:0001036)3.06350914
35Increased intramyocellular lipid droplets (HP:0012240)2.98295063
36Type I transferrin isoform profile (HP:0003642)2.84318538
37Congenital, generalized hypertrichosis (HP:0004540)2.77952133
38Abnormality of renal resorption (HP:0011038)2.75789837
39Abnormal hemoglobin (HP:0011902)2.69577325
40Exercise intolerance (HP:0003546)2.67131037
41Respiratory failure (HP:0002878)2.62292079
42Irregular epiphyses (HP:0010582)2.56384632
43Increased muscle lipid content (HP:0009058)2.55160828
44Congenital ichthyosiform erythroderma (HP:0007431)2.54302214
45Respiratory difficulties (HP:0002880)2.50468253
46Poor head control (HP:0002421)2.47071698
47Increased serum lactate (HP:0002151)2.42223093
48Dyschromatopsia (HP:0007641)2.35984834
49Nausea (HP:0002018)2.35106195
50Abnormality of urine glucose concentration (HP:0011016)2.33235940
51Glycosuria (HP:0003076)2.33235940
52Aplastic anemia (HP:0001915)2.33164252
53Vacuolated lymphocytes (HP:0001922)2.30418590
54Carpal bone hypoplasia (HP:0001498)2.29315941
55Hyperphosphaturia (HP:0003109)2.28709864
56Optic disc pallor (HP:0000543)2.22383714
5711 pairs of ribs (HP:0000878)2.21916571
58Paralysis (HP:0003470)2.21753137
59Abnormality of secondary sexual hair (HP:0009888)2.21158023
60Abnormality of the axillary hair (HP:0100134)2.21158023
61Abnormal protein N-linked glycosylation (HP:0012347)2.16628785
62Abnormal protein glycosylation (HP:0012346)2.16628785
63Abnormal glycosylation (HP:0012345)2.16628785
64Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.16628785
65Poikilocytosis (HP:0004447)2.13788228
66Cerebral edema (HP:0002181)2.13107092
67Oral leukoplakia (HP:0002745)2.12879212
68Beaking of vertebral bodies (HP:0004568)2.10137804
69Lactic acidosis (HP:0003128)2.10048953
70Lethargy (HP:0001254)2.02883149
71Abnormal pupillary function (HP:0007686)2.00970953
72Recurrent abscess formation (HP:0002722)2.00446318
73Metaphyseal dysplasia (HP:0100255)2.00400598
74Abnormal ciliary motility (HP:0012262)2.00056600
75Decreased central vision (HP:0007663)1.99423909
76Sparse eyelashes (HP:0000653)1.99221838
77Secondary amenorrhea (HP:0000869)1.97674843
78Leukodystrophy (HP:0002415)1.95647647
79Flat capital femoral epiphysis (HP:0003370)1.95402539
80Delayed epiphyseal ossification (HP:0002663)1.95010197
81Rough bone trabeculation (HP:0100670)1.94969959
82X-linked dominant inheritance (HP:0001423)1.92954018
83Aplasia/hypoplasia of the uterus (HP:0008684)1.92696976
84Spontaneous hematomas (HP:0007420)1.92009393
85Epiphyseal dysplasia (HP:0002656)1.90452358
86Small epiphyses (HP:0010585)1.89249755
87Acanthocytosis (HP:0001927)1.86108758
88Patchy hypopigmentation of hair (HP:0011365)1.85700357
89Vertebral compression fractures (HP:0002953)1.85264557
90Genu varum (HP:0002970)1.83966706
91Increased IgM level (HP:0003496)1.83693098
92Stomatitis (HP:0010280)1.82452394
93Abnormal urine phosphate concentration (HP:0012599)1.80413474
94Pancreatic cysts (HP:0001737)1.80398340
95Concave nail (HP:0001598)1.80256732
96Petechiae (HP:0000967)1.79033210
97Abnormal respiratory motile cilium morphology (HP:0005938)1.78376506
98Abnormal respiratory epithelium morphology (HP:0012253)1.78376506
99Abnormality of the phalanges of the 2nd finger (HP:0009541)1.76457476
100Hepatosplenomegaly (HP:0001433)1.76166102
101Breast hypoplasia (HP:0003187)1.75992620
102Recurrent bacterial skin infections (HP:0005406)1.75342131
103Glossoptosis (HP:0000162)1.75151529
104Abnormal respiratory motile cilium physiology (HP:0012261)1.74901233
105Septo-optic dysplasia (HP:0100842)1.74742440
106Reduced antithrombin III activity (HP:0001976)1.73296151
107Trismus (HP:0000211)1.71983882
108Renal tubular dysfunction (HP:0000124)1.71918156
109Tinnitus (HP:0000360)1.71913384
110Abnormality of the heme biosynthetic pathway (HP:0010472)1.70687867
111Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.70320419
112Abnormality of lateral ventricle (HP:0030047)1.69614022
113Irregular vertebral endplates (HP:0003301)1.69444965
114Partial duplication of thumb phalanx (HP:0009944)1.67594754
115Partial duplication of the phalanx of hand (HP:0009999)1.67535470
116Generalized aminoaciduria (HP:0002909)1.67014182
117Molar tooth sign on MRI (HP:0002419)1.65862178
118Abnormality of midbrain morphology (HP:0002418)1.65862178
119Microvesicular hepatic steatosis (HP:0001414)1.65619853
120Premature rupture of membranes (HP:0001788)1.65505748
121Hypothermia (HP:0002045)1.65498029
122Pancreatic fibrosis (HP:0100732)1.65419286
123Depressed nasal ridge (HP:0000457)1.64851924
124Abnormal tarsal ossification (HP:0008369)1.63738240
125Muscle fiber atrophy (HP:0100295)1.62237979
126Increased serum pyruvate (HP:0003542)1.62074341
127Abnormality of glycolysis (HP:0004366)1.62074341
128Purpura (HP:0000979)1.61612993
129True hermaphroditism (HP:0010459)1.61431086
130Abnormal trabecular bone morphology (HP:0100671)1.60188538
131Bruising susceptibility (HP:0000978)1.59514951
132Type 2 muscle fiber atrophy (HP:0003554)1.59357074
133Aplasia/Hypoplasia of the fovea (HP:0008060)1.59023021
134Hypoplasia of the fovea (HP:0007750)1.59023021
135Delayed cranial suture closure (HP:0000270)1.58360659
136Conjunctival telangiectasia (HP:0000524)1.57013660
137Amniotic constriction ring (HP:0009775)1.56651219
138Abnormality of placental membranes (HP:0011409)1.56651219
139Thrombocytosis (HP:0001894)1.56158234
140Adrenal hypoplasia (HP:0000835)1.55285449
141Absent/shortened dynein arms (HP:0200106)1.54560780
142Dynein arm defect of respiratory motile cilia (HP:0012255)1.54560780
143Degeneration of anterior horn cells (HP:0002398)1.54459648
144Abnormality of the anterior horn cell (HP:0006802)1.54459648
145Joint swelling (HP:0001386)1.53415591
146Pancytopenia (HP:0001876)1.51140373
147Abnormality of aromatic amino acid family metabolism (HP:0004338)1.49374060

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.12164688
2NME24.42363787
3STK163.13968136
4MST43.12036599
5PBK2.94031378
6PIM22.88993363
7BUB12.80294815
8EIF2AK12.77856915
9RIPK42.61945561
10VRK12.59756807
11TLK12.51969247
12EIF2AK32.31413315
13IRAK32.27277457
14TESK21.92624414
15WEE11.89696614
16BMX1.85277885
17NME11.75024382
18IRAK41.69870361
19GRK51.58837894
20BLK1.57154072
21TAF11.55729008
22EPHB21.54403142
23SRPK11.52693413
24TEC1.52680322
25STK391.51637625
26KDR1.50416216
27PLK41.47200486
28MYLK1.46532734
29MUSK1.41920085
30TAOK31.41873885
31BMPR1B1.38625260
32MAPK151.36402699
33LIMK11.34025262
34PTK2B1.29608974
35ZAK1.26331859
36IRAK11.24188933
37ABL21.22943090
38MAPKAPK51.20926213
39TESK11.20741583
40SYK1.20015413
41LRRK21.07651046
42MAP3K31.07589507
43PIK3CG1.07067855
44NEK91.03895176
45GRK61.03316381
46BRSK21.01192921
47MKNK10.99106822
48NUAK10.99000410
49CDK80.98545279
50RPS6KA50.98505597
51MKNK20.95970196
52MAP4K20.93971000
53CSF1R0.93546893
54PNCK0.92546813
55IKBKB0.91833977
56MAPKAPK30.91537226
57STK30.90627633
58WNK40.90421264
59EIF2AK20.86223197
60BTK0.84257385
61RPS6KA40.82312367
62PLK30.82267873
63NLK0.81619330
64IRAK20.80835150
65ADRBK20.80312361
66TXK0.80086026
67DYRK30.78323088
68MAP2K20.74652235
69ZAP700.74514379
70BCR0.72972322
71KIT0.71133208
72PASK0.70937748
73WNK30.70343101
74OXSR10.70067236
75PRKG20.69107045
76PIM10.68751520
77LYN0.67914943
78TRIM280.67820021
79BCKDK0.67611984
80ARAF0.66781145
81CSNK2A10.66470094
82DYRK20.65293287
83ILK0.64879654
84GRK70.62711957
85RPS6KB20.62169706
86TBK10.61967371
87AURKA0.60746233
88AURKB0.59407475
89DAPK10.58945644
90CDK190.58117990
91TYK20.57982754
92CDK70.56320269
93ACVR1B0.56160965
94MAP3K140.53256484
95STK40.53075604
96EPHA20.52612672
97INSRR0.51528166
98CLK10.50979388
99MATK0.50927423
100CSNK2A20.50786942
101MAP3K110.49324137
102MAP4K10.49238376
103MET0.49133261
104PLK20.48485645
105IKBKE0.48079859
106ITK0.47580091
107HCK0.46675225
108MAPK40.46033978
109PRKCG0.45998139
110MAP3K120.45891289
111GRK10.45419374
112ADRBK10.45287815
113BRAF0.45028669
114PRKCD0.44217430
115YES10.44214040
116NEK60.44206832
117DAPK30.43949396
118BMPR20.42980284
119TGFBR10.42551100
120PAK10.42411329
121TIE10.41728745
122PKN10.41688965
123MAPKAPK20.41331587
124TNK20.41143001
125FLT30.40573107
126OBSCN0.39965674
127MAP3K50.39576211
128LCK0.39538354
129PLK10.37353293
130PRKCQ0.36587504
131PRKG10.35722146
132CSNK1G30.35204962
133TNIK0.34566738
134MARK30.34073661
135STK240.33922449
136TAOK20.33253096
137PRKCE0.33206946
138PRKCA0.33057766
139PRKACA0.31329385
140EPHA30.31293988
141FGR0.30988623
142ERBB20.29391963

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.04371863
2Protein export_Homo sapiens_hsa030604.60798374
3Oxidative phosphorylation_Homo sapiens_hsa001903.94999486
4Proteasome_Homo sapiens_hsa030503.69718039
5Parkinsons disease_Homo sapiens_hsa050123.29808076
6RNA polymerase_Homo sapiens_hsa030203.16407863
7Huntingtons disease_Homo sapiens_hsa050162.46568847
8Alzheimers disease_Homo sapiens_hsa050102.36003900
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.35082919
10Pyrimidine metabolism_Homo sapiens_hsa002401.99448772
11DNA replication_Homo sapiens_hsa030301.89973934
12Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.84791490
13Homologous recombination_Homo sapiens_hsa034401.67450630
14Spliceosome_Homo sapiens_hsa030401.61188797
15Mismatch repair_Homo sapiens_hsa034301.56598948
16Nitrogen metabolism_Homo sapiens_hsa009101.55028318
17Platelet activation_Homo sapiens_hsa046111.50693112
18Nucleotide excision repair_Homo sapiens_hsa034201.45324478
19Folate biosynthesis_Homo sapiens_hsa007901.44496805
20Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.43995125
21Basal transcription factors_Homo sapiens_hsa030221.38183831
22Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.37361507
23Sulfur metabolism_Homo sapiens_hsa009201.36525137
24SNARE interactions in vesicular transport_Homo sapiens_hsa041301.35066842
25Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.31696201
26Fatty acid elongation_Homo sapiens_hsa000621.29465234
27Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.27638268
28Glutathione metabolism_Homo sapiens_hsa004801.23411347
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.23119084
30Arachidonic acid metabolism_Homo sapiens_hsa005901.17166513
31Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.13533509
32Steroid biosynthesis_Homo sapiens_hsa001001.06411611
33Base excision repair_Homo sapiens_hsa034101.02350830
34Purine metabolism_Homo sapiens_hsa002301.02198859
35Graft-versus-host disease_Homo sapiens_hsa053321.00353925
36Maturity onset diabetes of the young_Homo sapiens_hsa049501.00206865
37Sphingolipid metabolism_Homo sapiens_hsa006000.97852980
38Malaria_Homo sapiens_hsa051440.96208763
39Other glycan degradation_Homo sapiens_hsa005110.95522503
40Asthma_Homo sapiens_hsa053100.92651965
41RNA degradation_Homo sapiens_hsa030180.90718664
42Rheumatoid arthritis_Homo sapiens_hsa053230.89055691
43Cardiac muscle contraction_Homo sapiens_hsa042600.87764292
44Allograft rejection_Homo sapiens_hsa053300.86842031
45Non-homologous end-joining_Homo sapiens_hsa034500.80917755
46RNA transport_Homo sapiens_hsa030130.80736517
47Sulfur relay system_Homo sapiens_hsa041220.80706011
48Fanconi anemia pathway_Homo sapiens_hsa034600.79643162
49Vibrio cholerae infection_Homo sapiens_hsa051100.77915240
50Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.77069708
51Linoleic acid metabolism_Homo sapiens_hsa005910.74917609
52Primary bile acid biosynthesis_Homo sapiens_hsa001200.73592913
53Hematopoietic cell lineage_Homo sapiens_hsa046400.73061482
54Phototransduction_Homo sapiens_hsa047440.70147235
55Metabolic pathways_Homo sapiens_hsa011000.69585800
56Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.67938905
57Fat digestion and absorption_Homo sapiens_hsa049750.67405785
58Autoimmune thyroid disease_Homo sapiens_hsa053200.64444119
59Ether lipid metabolism_Homo sapiens_hsa005650.64142883
60Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.64025431
61N-Glycan biosynthesis_Homo sapiens_hsa005100.63675749
62Histidine metabolism_Homo sapiens_hsa003400.62669615
63Legionellosis_Homo sapiens_hsa051340.62649484
64Olfactory transduction_Homo sapiens_hsa047400.62038613
65Epstein-Barr virus infection_Homo sapiens_hsa051690.59856144
66Intestinal immune network for IgA production_Homo sapiens_hsa046720.59208239
67Steroid hormone biosynthesis_Homo sapiens_hsa001400.57530190
68Phagosome_Homo sapiens_hsa041450.57269751
69Cell cycle_Homo sapiens_hsa041100.57054250
70Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.56741837
71p53 signaling pathway_Homo sapiens_hsa041150.54878899
72Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.54561381
73Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.54131103
74alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.52800165
75Alcoholism_Homo sapiens_hsa050340.52638323
76Systemic lupus erythematosus_Homo sapiens_hsa053220.52367442
77One carbon pool by folate_Homo sapiens_hsa006700.52071331
78Serotonergic synapse_Homo sapiens_hsa047260.49177115
79Pertussis_Homo sapiens_hsa051330.49152869
80Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.48804234
81Antigen processing and presentation_Homo sapiens_hsa046120.48069024
82Collecting duct acid secretion_Homo sapiens_hsa049660.47643760
83Lysosome_Homo sapiens_hsa041420.46736162
84NF-kappa B signaling pathway_Homo sapiens_hsa040640.46508720
85Herpes simplex infection_Homo sapiens_hsa051680.45055700
86Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.44850052
87NOD-like receptor signaling pathway_Homo sapiens_hsa046210.43735807
88Tyrosine metabolism_Homo sapiens_hsa003500.43252326
89Chemical carcinogenesis_Homo sapiens_hsa052040.42406980
90Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.41982911
91Retinol metabolism_Homo sapiens_hsa008300.41965226
92beta-Alanine metabolism_Homo sapiens_hsa004100.39440754
93Caffeine metabolism_Homo sapiens_hsa002320.39258534
94Arginine and proline metabolism_Homo sapiens_hsa003300.38772278
95Glycerolipid metabolism_Homo sapiens_hsa005610.37398744
96Leishmaniasis_Homo sapiens_hsa051400.37292501
97Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.36476056
98Pentose and glucuronate interconversions_Homo sapiens_hsa000400.35285077
99Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.34863890
100Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.33739110
101Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.32009440
102Phenylalanine metabolism_Homo sapiens_hsa003600.31248085
103Pentose phosphate pathway_Homo sapiens_hsa000300.30596699
104Measles_Homo sapiens_hsa051620.30182296
105Primary immunodeficiency_Homo sapiens_hsa053400.29857447
106Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.29472358
107ECM-receptor interaction_Homo sapiens_hsa045120.29459670
108Regulation of autophagy_Homo sapiens_hsa041400.28703339
109Butanoate metabolism_Homo sapiens_hsa006500.27402880
110Chemokine signaling pathway_Homo sapiens_hsa040620.27073821
111Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.26417335
112Vascular smooth muscle contraction_Homo sapiens_hsa042700.25997394
113Staphylococcus aureus infection_Homo sapiens_hsa051500.25427216
114Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.23644332
115Vitamin digestion and absorption_Homo sapiens_hsa049770.23140108
116Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.22921752
117Type I diabetes mellitus_Homo sapiens_hsa049400.22874062
118RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.21746008
119Renin-angiotensin system_Homo sapiens_hsa046140.21617747
120African trypanosomiasis_Homo sapiens_hsa051430.20699443
121Galactose metabolism_Homo sapiens_hsa000520.20322634
122Peroxisome_Homo sapiens_hsa041460.20062534
123Drug metabolism - other enzymes_Homo sapiens_hsa009830.19547575
124Tryptophan metabolism_Homo sapiens_hsa003800.19366014
125Cysteine and methionine metabolism_Homo sapiens_hsa002700.19210531
126Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.18697968
127TGF-beta signaling pathway_Homo sapiens_hsa043500.16023713
128Shigellosis_Homo sapiens_hsa051310.15621546

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