OSGEP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.23870279
2DNA deamination (GO:0045006)5.99670015
3viral transcription (GO:0019083)5.33823868
4ribosomal small subunit biogenesis (GO:0042274)5.18376505
5deoxyribonucleoside monophosphate metabolic process (GO:0009162)5.16948066
6translational termination (GO:0006415)5.13021996
7telomere maintenance via semi-conservative replication (GO:0032201)4.99608564
8DNA strand elongation involved in DNA replication (GO:0006271)4.96465156
9DNA strand elongation (GO:0022616)4.74604874
10SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.67426881
11cotranslational protein targeting to membrane (GO:0006613)4.60749622
12protein targeting to ER (GO:0045047)4.55685119
13translational elongation (GO:0006414)4.50199890
14maturation of SSU-rRNA (GO:0030490)4.49592265
15telomere maintenance via recombination (GO:0000722)4.40948362
16DNA replication initiation (GO:0006270)4.39860402
17ribosomal large subunit biogenesis (GO:0042273)4.38194513
18protein localization to endoplasmic reticulum (GO:0070972)4.32146893
19establishment of protein localization to endoplasmic reticulum (GO:0072599)4.31377457
20mitotic recombination (GO:0006312)4.09295728
21proteasome assembly (GO:0043248)4.08694768
22establishment of integrated proviral latency (GO:0075713)4.07919494
23viral life cycle (GO:0019058)4.06794820
24mitochondrial respiratory chain complex assembly (GO:0033108)3.99116456
25translational initiation (GO:0006413)3.93683872
26cellular protein complex disassembly (GO:0043624)3.91944252
27nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.90888020
28telomere maintenance via telomere lengthening (GO:0010833)3.87699740
29nucleotide-excision repair, DNA gap filling (GO:0006297)3.80450079
30cytochrome complex assembly (GO:0017004)3.76380695
31ribonucleoprotein complex biogenesis (GO:0022613)3.68018588
32pseudouridine synthesis (GO:0001522)3.64787526
33DNA unwinding involved in DNA replication (GO:0006268)3.61258449
34termination of RNA polymerase III transcription (GO:0006386)3.59681179
35transcription elongation from RNA polymerase III promoter (GO:0006385)3.59681179
36translation (GO:0006412)3.57403170
37CENP-A containing nucleosome assembly (GO:0034080)3.52489011
38transcription-coupled nucleotide-excision repair (GO:0006283)3.51749766
39spliceosomal snRNP assembly (GO:0000387)3.44850227
40chromatin remodeling at centromere (GO:0031055)3.44545544
41protein complex disassembly (GO:0043241)3.44441250
42exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.39854261
43nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.38422261
44establishment of viral latency (GO:0019043)3.31232448
45rRNA processing (GO:0006364)3.27820379
46negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.27629049
47respiratory chain complex IV assembly (GO:0008535)3.27004452
48mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.26345235
49macromolecular complex disassembly (GO:0032984)3.26154718
50DNA replication checkpoint (GO:0000076)3.25619226
51peptidyl-histidine modification (GO:0018202)3.22968727
52cellular component biogenesis (GO:0044085)3.21185627
53rRNA metabolic process (GO:0016072)3.16179864
54spliceosomal complex assembly (GO:0000245)3.15711702
55regulation of B cell receptor signaling pathway (GO:0050855)3.15437204
56rRNA modification (GO:0000154)3.14789581
57regulation of mitochondrial translation (GO:0070129)3.13823357
58nuclear-transcribed mRNA catabolic process (GO:0000956)3.13122456
59deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.12146774
60mannosylation (GO:0097502)3.11885733
61DNA damage response, detection of DNA damage (GO:0042769)3.11815087
62formation of translation preinitiation complex (GO:0001731)3.10954556
63L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.05665621
64regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.04765991
65negative regulation of ligase activity (GO:0051352)3.04138233
66negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.04138233
67signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.03442354
68signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.03442354
69nucleobase biosynthetic process (GO:0046112)3.01908803
70IMP biosynthetic process (GO:0006188)3.01343994
71mitochondrial respiratory chain complex I assembly (GO:0032981)3.00890123
72NADH dehydrogenase complex assembly (GO:0010257)3.00890123
73mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.00890123
74recombinational repair (GO:0000725)3.00862344
75somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.00846845
76isotype switching (GO:0045190)3.00846845
77somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.00846845
78double-strand break repair via homologous recombination (GO:0000724)3.00038721
79iron-sulfur cluster assembly (GO:0016226)2.97856721
80metallo-sulfur cluster assembly (GO:0031163)2.97856721
81DNA ligation (GO:0006266)2.97725447
82viral mRNA export from host cell nucleus (GO:0046784)2.97621219
83mRNA catabolic process (GO:0006402)2.97328593
84positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.96606347
85positive regulation of B cell differentiation (GO:0045579)2.96409757
86regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.96116578
87pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.95411045
88deoxyribonucleotide biosynthetic process (GO:0009263)2.94640874
89DNA catabolic process, exonucleolytic (GO:0000738)2.94179024
90signal transduction involved in cell cycle checkpoint (GO:0072395)2.94162976
91pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.93763148
92energy coupled proton transport, down electrochemical gradient (GO:0015985)2.93549517
93ATP synthesis coupled proton transport (GO:0015986)2.93549517
94histone H2A acetylation (GO:0043968)2.93257219
95signal transduction involved in DNA integrity checkpoint (GO:0072401)2.92970405
96signal transduction involved in DNA damage checkpoint (GO:0072422)2.92970405
97anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.91638964
98DNA replication-independent nucleosome organization (GO:0034724)2.90606141
99DNA replication-independent nucleosome assembly (GO:0006336)2.90606141
100protein K6-linked ubiquitination (GO:0085020)2.89734892
101cullin deneddylation (GO:0010388)2.89301311
102DNA double-strand break processing (GO:0000729)2.88963105
103antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.87895956
104pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.86613200
105purine nucleobase biosynthetic process (GO:0009113)2.86582380
106telomere organization (GO:0032200)2.85101744
107centriole replication (GO:0007099)2.84920666
108RNA catabolic process (GO:0006401)2.84861356
109* adenosine metabolic process (GO:0046085)2.84599769
1107-methylguanosine RNA capping (GO:0009452)2.84272649
111RNA capping (GO:0036260)2.84272649
112DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.84174230
113telomere maintenance (GO:0000723)2.84167997
114regulation of cellular amino acid metabolic process (GO:0006521)2.83903067
115deoxyribose phosphate biosynthetic process (GO:0046385)2.83856002
1162-deoxyribonucleotide biosynthetic process (GO:0009265)2.83856002
117protein targeting to membrane (GO:0006612)2.83815137
118protein complex biogenesis (GO:0070271)2.81185057
119replication fork processing (GO:0031297)2.81131354
120pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.80892168
121intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.79078011
122signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.79078011
123somatic diversification of immune receptors via somatic mutation (GO:0002566)2.78621912
124somatic hypermutation of immunoglobulin genes (GO:0016446)2.78621912
125mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.77820622
126signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.77786549
127positive regulation of granulocyte differentiation (GO:0030854)2.75460718
128preassembly of GPI anchor in ER membrane (GO:0016254)2.75212546
129tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.73920361
130RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.73920361
131protein deneddylation (GO:0000338)2.73240364
132mismatch repair (GO:0006298)2.69670145
133RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.68384347
134negative regulation of mRNA processing (GO:0050686)2.66117985
135base-excision repair, AP site formation (GO:0006285)2.65287892
136purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.64365334
137kinetochore assembly (GO:0051382)2.61348041
138* tRNA processing (GO:0008033)2.59576974
139GMP metabolic process (GO:0046037)2.59269925
140neural tube formation (GO:0001841)2.57773665
141negative regulation of B cell apoptotic process (GO:0002903)2.57013164
142C-terminal protein lipidation (GO:0006501)2.56089003
143water-soluble vitamin biosynthetic process (GO:0042364)2.55049955
144regulation of B cell apoptotic process (GO:0002902)2.55030608
145maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.54520610
146regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.53023386
147regulation of mitotic spindle checkpoint (GO:1903504)2.53023386
148positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.52080930
149purine deoxyribonucleotide catabolic process (GO:0009155)2.49692531
150DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.49402473
151fucose catabolic process (GO:0019317)2.45613960
152L-fucose metabolic process (GO:0042354)2.45613960
153L-fucose catabolic process (GO:0042355)2.45613960
154respiratory electron transport chain (GO:0022904)2.45136591
155negative regulation of DNA-dependent DNA replication (GO:2000104)2.44784572
156negative regulation of mast cell activation (GO:0033004)2.44742899
157electron transport chain (GO:0022900)2.42514380
158regulation of translation in response to stress (GO:0043555)2.42005066

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.45295735
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.25127921
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.16569470
4* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.78460696
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.61571427
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.54836897
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.48051444
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.44270091
9ELF1_17652178_ChIP-ChIP_JURKAT_Human3.32361139
10HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.15606048
11ETS1_20019798_ChIP-Seq_JURKAT_Human3.08687711
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.06900021
13CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.94535269
14NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.92141242
15E2F4_17652178_ChIP-ChIP_JURKAT_Human2.90667391
16* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.69329618
17* CREB1_15753290_ChIP-ChIP_HEK293T_Human2.66971876
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.57885160
19* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.56083954
20* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.55646045
21VDR_23849224_ChIP-Seq_CD4+_Human2.53966764
22FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.43591515
23XRN2_22483619_ChIP-Seq_HELA_Human2.35877766
24SRF_21415370_ChIP-Seq_HL-1_Mouse2.29347855
25SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.27760367
26ZNF274_21170338_ChIP-Seq_K562_Hela2.24275919
27DCP1A_22483619_ChIP-Seq_HELA_Human2.22916360
28E2F1_18555785_ChIP-Seq_MESCs_Mouse2.16626647
29FOXP3_21729870_ChIP-Seq_TREG_Human2.12623799
30E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.12235536
31TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.08033104
32NELFA_20434984_ChIP-Seq_ESCs_Mouse2.05669412
33TTF2_22483619_ChIP-Seq_HELA_Human1.98173630
34YY1_21170310_ChIP-Seq_MESCs_Mouse1.97894502
35MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.94947531
36THAP11_20581084_ChIP-Seq_MESCs_Mouse1.94243627
37FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.93923977
38FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.93225197
39FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.81982618
40GABP_19822575_ChIP-Seq_HepG2_Human1.81328244
41* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.77444604
42ERG_20887958_ChIP-Seq_HPC-7_Mouse1.76800651
43SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.70791339
44ELK1_19687146_ChIP-ChIP_HELA_Human1.69619143
45CIITA_25753668_ChIP-Seq_RAJI_Human1.66021104
46ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.64626816
47SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.61675735
48FOXM1_23109430_ChIP-Seq_U2OS_Human1.58526637
49SALL1_21062744_ChIP-ChIP_HESCs_Human1.58444431
50CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.54211479
51PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.48284051
52IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.45413315
53PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.44581529
54NOTCH1_21737748_ChIP-Seq_TLL_Human1.43681147
55* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.42061955
56E2F1_21310950_ChIP-Seq_MCF-7_Human1.41488677
57CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.39905405
58MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.38940176
59MYC_18940864_ChIP-ChIP_HL60_Human1.36804291
60YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.34845376
61NANOG_18555785_ChIP-Seq_MESCs_Mouse1.34760287
62SPI1_23547873_ChIP-Seq_NB4_Human1.33442698
63MYB_26560356_Chip-Seq_TH2_Human1.33108272
64ZFX_18555785_ChIP-Seq_MESCs_Mouse1.32818317
65POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.31536904
66GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.29332635
67MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.23723558
68KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.22074836
69GATA3_26560356_Chip-Seq_TH2_Human1.19632276
70POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.16626181
71AR_21909140_ChIP-Seq_LNCAP_Human1.14741699
72CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.13970299
73VDR_21846776_ChIP-Seq_THP-1_Human1.13036634
74EWS_26573619_Chip-Seq_HEK293_Human1.12645946
75VDR_22108803_ChIP-Seq_LS180_Human1.12449286
76* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.12078080
77IRF1_19129219_ChIP-ChIP_H3396_Human1.11895722
78ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.10966504
79IRF8_22096565_ChIP-ChIP_GC-B_Human1.10753810
80HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.09692891
81CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.08869552
82TP53_22573176_ChIP-Seq_HFKS_Human1.07011307
83IRF8_21731497_ChIP-ChIP_J774_Mouse1.05417473
84* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.03957935
85SCL_19346495_ChIP-Seq_HPC-7_Human1.03813916
86IGF1R_20145208_ChIP-Seq_DFB_Human1.03331655
87ELK1_22589737_ChIP-Seq_MCF10A_Human1.02609892
88RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.00467314
89ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.99732813
90STAT4_19710469_ChIP-ChIP_TH1__Mouse0.98503683
91GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98344868
92SOX2_18555785_ChIP-Seq_MESCs_Mouse0.96491005
93EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.95928456
94TP63_19390658_ChIP-ChIP_HaCaT_Human0.95561612
95* KDM5A_27292631_Chip-Seq_BREAST_Human0.94600614
96BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.92784845
97MYB_26560356_Chip-Seq_TH1_Human0.92283299
98TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.92093713
99GATA3_27048872_Chip-Seq_THYMUS_Human0.92080436
100TFEB_21752829_ChIP-Seq_HELA_Human0.91273542
101FUS_26573619_Chip-Seq_HEK293_Human0.91141252
102EGR1_23403033_ChIP-Seq_LIVER_Mouse0.90253709
103MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.90159231
104LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.90049783
105CTCF_18555785_ChIP-Seq_MESCs_Mouse0.89991540
106FLI1_27457419_Chip-Seq_LIVER_Mouse0.88861550
107HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.86535291
108DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.84336639
109FOXA1_25329375_ChIP-Seq_VCAP_Human0.83156993
110FOXA1_27270436_Chip-Seq_PROSTATE_Human0.83156993
111CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.82677553
112* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81870767
113SRY_22984422_ChIP-ChIP_TESTIS_Rat0.81607009
114MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.81567809
115AR_20517297_ChIP-Seq_VCAP_Human0.81391815
116* EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.80367743
117PADI4_21655091_ChIP-ChIP_MCF-7_Human0.79021498
118STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.78685558
119GATA1_22383799_ChIP-Seq_G1ME_Mouse0.77957756
120PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.77843399
121CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.77830780
122GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.77471177
123RBPJ_22232070_ChIP-Seq_NCS_Mouse0.77342402
124PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.77166323
125YY1_22570637_ChIP-Seq_MALME-3M_Human0.76694601
126MYC_22102868_ChIP-Seq_BL_Human0.71719478

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching3.84504694
2MP0010094_abnormal_chromosome_stability3.51540582
3MP0008058_abnormal_DNA_repair3.48663030
4MP0004957_abnormal_blastocyst_morpholog3.05211274
5MP0002396_abnormal_hematopoietic_system2.98413437
6MP0003111_abnormal_nucleus_morphology2.98252735
7MP0008057_abnormal_DNA_replication2.92122401
8MP0002132_abnormal_respiratory_system2.69341133
9MP0003077_abnormal_cell_cycle2.64607264
10MP0008007_abnormal_cellular_replicative2.42880730
11MP0009697_abnormal_copulation2.39409770
12MP0009379_abnormal_foot_pigmentation2.31794736
13MP0001835_abnormal_antigen_presentation2.29461983
14MP0000490_abnormal_crypts_of2.14707469
15MP0006292_abnormal_olfactory_placode2.10355042
16MP0008932_abnormal_embryonic_tissue2.08931769
17MP0003195_calcinosis2.01490848
18MP0000569_abnormal_digit_pigmentation1.99300344
19MP0000685_abnormal_immune_system1.96698634
20MP0003786_premature_aging1.94096085
21MP0004043_abnormal_pH_regulation1.92821722
22MP0003763_abnormal_thymus_physiology1.88836653
23MP0004147_increased_porphyrin_level1.88148454
24MP0008872_abnormal_physiological_respon1.88087997
25MP0003136_yellow_coat_color1.88015480
26MP0002148_abnormal_hypersensitivity_rea1.69512050
27MP0009785_altered_susceptibility_to1.68551562
28MP0009333_abnormal_splenocyte_physiolog1.67219393
29MP0003186_abnormal_redox_activity1.63152084
30MP0005075_abnormal_melanosome_morpholog1.62667818
31MP0005671_abnormal_response_to1.61916704
32MP0002163_abnormal_gland_morphology1.53889624
33MP0001986_abnormal_taste_sensitivity1.50051912
34MP0003011_delayed_dark_adaptation1.46951741
35MP0001853_heart_inflammation1.46625811
36MP0002277_abnormal_respiratory_mucosa1.46061742
37MP0002138_abnormal_hepatobiliary_system1.44629252
38MP0005551_abnormal_eye_electrophysiolog1.43569588
39MP0002398_abnormal_bone_marrow1.43275078
40MP0005025_abnormal_response_to1.42992984
41MP0005646_abnormal_pituitary_gland1.42859545
42MP0001800_abnormal_humoral_immune1.42455948
43MP0006036_abnormal_mitochondrial_physio1.37485288
44MP0003315_abnormal_perineum_morphology1.37329161
45MP0000689_abnormal_spleen_morphology1.35406490
46MP0001529_abnormal_vocalization1.32681615
47MP0005000_abnormal_immune_tolerance1.31700674
48MP0003724_increased_susceptibility_to1.31265575
49MP0002722_abnormal_immune_system1.31028361
50MP0002452_abnormal_antigen_presenting1.30725417
51MP0000465_gastrointestinal_hemorrhage1.29901011
52MP0002420_abnormal_adaptive_immunity1.29393231
53MP0004381_abnormal_hair_follicle1.27445420
54MP0001819_abnormal_immune_cell1.26429186
55MP0005645_abnormal_hypothalamus_physiol1.25586534
56MP0000716_abnormal_immune_system1.24701466
57MP0003787_abnormal_imprinting1.24387905
58MP0008875_abnormal_xenobiotic_pharmacok1.23364294
59MP0002723_abnormal_immune_serum1.22925405
60MP0000313_abnormal_cell_death1.21764938
61MP0002429_abnormal_blood_cell1.21432069
62MP0002736_abnormal_nociception_after1.16634412
63MP0002822_catalepsy1.15410871
64MP0001790_abnormal_immune_system1.13455912
65MP0005387_immune_system_phenotype1.13455912
66MP0005379_endocrine/exocrine_gland_phen1.12376986
67MP0003656_abnormal_erythrocyte_physiolo1.12197579
68MP0000015_abnormal_ear_pigmentation1.11877159
69MP0002095_abnormal_skin_pigmentation1.11128300
70MP0002102_abnormal_ear_morphology1.10523365
71MP0000703_abnormal_thymus_morphology1.10471919
72MP0008877_abnormal_DNA_methylation1.09322318
73MP0002019_abnormal_tumor_incidence1.08929662
74MP0004133_heterotaxia1.08901068
75MP0002405_respiratory_system_inflammati1.08336266
76MP0000566_synostosis1.08217796
77MP0001293_anophthalmia1.07937993
78MP0005174_abnormal_tail_pigmentation1.06876248
79MP0000350_abnormal_cell_proliferation1.06610886
80MP0002938_white_spotting1.05183076
81MP0008260_abnormal_autophagy1.04563990
82MP0002638_abnormal_pupillary_reflex1.03582112
83MP0003718_maternal_effect1.03541458
84MP0001188_hyperpigmentation1.03440409
85MP0005464_abnormal_platelet_physiology1.02987260
86MP0001968_abnormal_touch/_nociception1.01953972
87MP0009764_decreased_sensitivity_to1.01695609
88MP0002210_abnormal_sex_determination1.00452866
89MP0002419_abnormal_innate_immunity0.99744019
90MP0006072_abnormal_retinal_apoptosis0.97573519
91MP0004808_abnormal_hematopoietic_stem0.96565182
92MP0008995_early_reproductive_senescence0.94597482
93MP0001545_abnormal_hematopoietic_system0.94306713
94MP0005397_hematopoietic_system_phenotyp0.94306713
95MP0003172_abnormal_lysosome_physiology0.94134983
96MP0005409_darkened_coat_color0.93594563
97MP0002876_abnormal_thyroid_physiology0.92945280
98MP0005084_abnormal_gallbladder_morpholo0.92246909
99MP0003436_decreased_susceptibility_to0.92125151
100MP0000613_abnormal_salivary_gland0.89890409
101MP0001929_abnormal_gametogenesis0.89698078
102MP0005310_abnormal_salivary_gland0.89240580
103MP0010155_abnormal_intestine_physiology0.88828388
104MP0000372_irregular_coat_pigmentation0.88004916
105MP0002166_altered_tumor_susceptibility0.86952467
106MP0009046_muscle_twitch0.86696836
107MP0000858_altered_metastatic_potential0.86369037
108MP0004742_abnormal_vestibular_system0.85080748
109MP0006035_abnormal_mitochondrial_morpho0.84973516
110MP0000049_abnormal_middle_ear0.83921047
111MP0001873_stomach_inflammation0.83672641
112MP0006054_spinal_hemorrhage0.83386020
113MP0005266_abnormal_metabolism0.83329877
114MP0003698_abnormal_male_reproductive0.81942975
115MP0004142_abnormal_muscle_tone0.80841755
116MP0003866_abnormal_defecation0.80638478
117MP0001730_embryonic_growth_arrest0.80184350
118MP0001919_abnormal_reproductive_system0.78728544
119MP0002693_abnormal_pancreas_physiology0.78285423
120MP0001145_abnormal_male_reproductive0.77525708
121MP0008789_abnormal_olfactory_epithelium0.76265334
122MP0000358_abnormal_cell_content/0.75815561
123MP0003252_abnormal_bile_duct0.75665540
124MP0001764_abnormal_homeostasis0.75454615
125MP0000631_abnormal_neuroendocrine_gland0.75365159
126MP0005253_abnormal_eye_physiology0.74823998
127MP0001119_abnormal_female_reproductive0.73705691
128MP0005451_abnormal_body_composition0.70989759
129MP0002160_abnormal_reproductive_system0.69155698
130MP0005389_reproductive_system_phenotype0.68566997
131MP0001905_abnormal_dopamine_level0.65737406
132MP0003806_abnormal_nucleotide_metabolis0.64966942
133MP0002249_abnormal_larynx_morphology0.62219531

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.52194549
2Abnormal number of erythroid precursors (HP:0012131)5.43656085
3Reticulocytopenia (HP:0001896)4.84606810
4Hepatocellular necrosis (HP:0001404)3.77091500
53-Methylglutaconic aciduria (HP:0003535)3.68286190
6Decreased activity of mitochondrial respiratory chain (HP:0008972)3.49912660
7Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.49912660
8Mitochondrial inheritance (HP:0001427)3.48438653
9Pallor (HP:0000980)3.40078022
10Hepatic necrosis (HP:0002605)3.39310444
11Macrocytic anemia (HP:0001972)3.36850827
12Type I transferrin isoform profile (HP:0003642)3.35253151
13Birth length less than 3rd percentile (HP:0003561)3.33704276
14Panhypogammaglobulinemia (HP:0003139)3.26391745
15Aplastic anemia (HP:0001915)3.22834537
16Aplasia/Hypoplasia of the sacrum (HP:0008517)3.15769911
17Microvesicular hepatic steatosis (HP:0001414)3.13899152
18Acute necrotizing encephalopathy (HP:0006965)3.08235781
19Absent rod-and cone-mediated responses on ERG (HP:0007688)3.05333477
20Increased hepatocellular lipid droplets (HP:0006565)3.04208347
21Increased CSF lactate (HP:0002490)3.02123501
22Increased serum lactate (HP:0002151)2.84393526
23Abnormal mitochondria in muscle tissue (HP:0008316)2.76277881
24Oral leukoplakia (HP:0002745)2.75857519
25Asplenia (HP:0001746)2.72086594
26Chromsome breakage (HP:0040012)2.68244529
27Lipid accumulation in hepatocytes (HP:0006561)2.68067497
28Nephronophthisis (HP:0000090)2.63208780
29Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.62822072
30Abnormality of the heme biosynthetic pathway (HP:0010472)2.59705002
31Chromosomal breakage induced by crosslinking agents (HP:0003221)2.59473119
32Breast hypoplasia (HP:0003187)2.57333863
33Chronic otitis media (HP:0000389)2.54800599
34Abnormal protein N-linked glycosylation (HP:0012347)2.51272585
35Abnormal protein glycosylation (HP:0012346)2.51272585
36Abnormal glycosylation (HP:0012345)2.51272585
37Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.51272585
38Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.48558393
39Abnormality of the preputium (HP:0100587)2.47317324
40Severe combined immunodeficiency (HP:0004430)2.45273727
41Abnormality of alanine metabolism (HP:0010916)2.43163445
42Hyperalaninemia (HP:0003348)2.43163445
43Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.43163445
44Aplasia/Hypoplasia of the spleen (HP:0010451)2.42844537
45Respiratory difficulties (HP:0002880)2.42250138
46Cerebral hypomyelination (HP:0006808)2.41419671
47Thrombocytosis (HP:0001894)2.40782447
48Acute encephalopathy (HP:0006846)2.40619016
49Abnormality of the prostate (HP:0008775)2.39430630
50Molar tooth sign on MRI (HP:0002419)2.38740041
51Abnormality of midbrain morphology (HP:0002418)2.38740041
52Exertional dyspnea (HP:0002875)2.37082867
53Prostate neoplasm (HP:0100787)2.36121048
54Type 2 muscle fiber atrophy (HP:0003554)2.33326317
55Cerebral edema (HP:0002181)2.31120561
56Pancytopenia (HP:0001876)2.29494831
57Muscle fiber atrophy (HP:0100295)2.28924013
58IgM deficiency (HP:0002850)2.27601993
59Exercise intolerance (HP:0003546)2.23405632
60CNS demyelination (HP:0007305)2.23283877
61Reduced antithrombin III activity (HP:0001976)2.22829476
62Microretrognathia (HP:0000308)2.21455764
63Progressive macrocephaly (HP:0004481)2.21279754
64Congenital stationary night blindness (HP:0007642)2.19999023
65Clubbing of toes (HP:0100760)2.19678675
66Abnormality of the ileum (HP:0001549)2.18956434
67Progressive microcephaly (HP:0000253)2.18369321
68Abnormal rod and cone electroretinograms (HP:0008323)2.18058380
69Meckel diverticulum (HP:0002245)2.18005210
70Renal Fanconi syndrome (HP:0001994)2.17503702
71Abnormality of T cell physiology (HP:0011840)2.17136508
72Duplicated collecting system (HP:0000081)2.16115286
73Degeneration of anterior horn cells (HP:0002398)2.15942117
74Abnormality of the anterior horn cell (HP:0006802)2.15942117
75Increased serum pyruvate (HP:0003542)2.15141157
76Abnormality of glycolysis (HP:0004366)2.15141157
77Petechiae (HP:0000967)2.12997680
78Elevated erythrocyte sedimentation rate (HP:0003565)2.12764674
7911 pairs of ribs (HP:0000878)2.11923237
80Bone marrow hypocellularity (HP:0005528)2.11849952
81True hermaphroditism (HP:0010459)2.10782753
82IgG deficiency (HP:0004315)2.10537688
83Methylmalonic aciduria (HP:0012120)2.10330728
84Absent thumb (HP:0009777)2.09618326
85Abnormality of the renal medulla (HP:0100957)2.09536140
86Lactic acidosis (HP:0003128)2.08850450
87Renal cortical cysts (HP:0000803)2.08192202
88Rough bone trabeculation (HP:0100670)2.08060871
89Abnormal delayed hypersensitivity skin test (HP:0002963)2.06913378
90Severe visual impairment (HP:0001141)2.06772177
91Premature graying of hair (HP:0002216)2.06688107
92Abnormality of the renal cortex (HP:0011035)2.05189284
93Stomatitis (HP:0010280)2.04827642
94Emotional lability (HP:0000712)2.04508812
95Triphalangeal thumb (HP:0001199)2.01437679
96Abnormality of the renal collecting system (HP:0004742)2.00474449
97Respiratory failure (HP:0002878)2.00471600
98Abnormality of B cell number (HP:0010975)2.00166147
99Dicarboxylic aciduria (HP:0003215)1.99007488
100Abnormality of dicarboxylic acid metabolism (HP:0010995)1.99007488
101Sparse eyelashes (HP:0000653)1.98991299
102Abnormality of DNA repair (HP:0003254)1.96870991
103Opisthotonus (HP:0002179)1.96687998
104Albinism (HP:0001022)1.95216151
105Combined immunodeficiency (HP:0005387)1.93955636
106Increased intramyocellular lipid droplets (HP:0012240)1.93539465
107Neutropenia (HP:0001875)1.93209643
108Medial flaring of the eyebrow (HP:0010747)1.92684776
109Methylmalonic acidemia (HP:0002912)1.92641528
110Myelodysplasia (HP:0002863)1.92342776
111Colon cancer (HP:0003003)1.91849716
112Abnormality of chromosome stability (HP:0003220)1.91529879
113Duplication of thumb phalanx (HP:0009942)1.89671995
114Agammaglobulinemia (HP:0004432)1.88734612
115Trismus (HP:0000211)1.88121756
116Sloping forehead (HP:0000340)1.87834276
117Abnormality of the pons (HP:0007361)1.87188235
118Supernumerary spleens (HP:0009799)1.86016586
119Lethargy (HP:0001254)1.85935383
120Partial duplication of thumb phalanx (HP:0009944)1.85014968
121Pancreatic cysts (HP:0001737)1.84926448
122Agnosia (HP:0010524)1.84185778
123Aplasia/Hypoplasia of the uvula (HP:0010293)1.83333977
124B lymphocytopenia (HP:0010976)1.81707587
125Poor head control (HP:0002421)1.81418219
126Lymphoma (HP:0002665)1.81045192
127Pendular nystagmus (HP:0012043)1.80859736
128Patellar aplasia (HP:0006443)1.80691015
129Optic disc pallor (HP:0000543)1.77910528
130Hypoplasia of the pons (HP:0012110)1.77129156
131Horseshoe kidney (HP:0000085)1.77115802
132Optic nerve coloboma (HP:0000588)1.76754105
133Small intestinal stenosis (HP:0012848)1.76717123
134Duodenal stenosis (HP:0100867)1.76717123
135Pancreatic fibrosis (HP:0100732)1.76441063
136Recurrent fungal infections (HP:0002841)1.75805912
137Attenuation of retinal blood vessels (HP:0007843)1.75392702
138Hypochromic microcytic anemia (HP:0004840)1.75356072
139Parakeratosis (HP:0001036)1.73594990
140Aplasia/Hypoplasia of the patella (HP:0006498)1.72832052
141Abnormality of the labia minora (HP:0012880)1.72436538
142Abolished electroretinogram (ERG) (HP:0000550)1.72163346
143Abnormality of T cells (HP:0002843)1.71597692
144Large for gestational age (HP:0001520)1.71464561
145Abnormality of lateral ventricle (HP:0030047)1.71152971
146Increased muscle lipid content (HP:0009058)1.70642575
147Recurrent cutaneous fungal infections (HP:0011370)1.70263629
148Chronic mucocutaneous candidiasis (HP:0002728)1.70263629

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK164.10203988
2NUAK14.06452238
3VRK23.82617974
4MAP4K23.45851187
5NME23.22949905
6BUB13.12252122
7FRK2.91316138
8WEE12.85694560
9VRK12.80310568
10TLK12.51371203
11CDC72.31933971
12DYRK32.14958706
13ACVR1B2.09575335
14SRPK12.08351897
15BLK2.05047226
16PBK1.98523426
17TNK21.89214070
18MAPKAPK31.75000488
19IRAK41.74493955
20TESK21.70441326
21MKNK11.63197714
22PIM21.61266616
23EIF2AK11.61213701
24CCNB11.60190518
25CDK191.55045064
26YES11.50681282
27CDK71.46296290
28MAP4K11.43287406
29PDK21.41564763
30TAOK31.41436991
31RPS6KA41.37167400
32MUSK1.36971280
33RPS6KB21.30280362
34CLK11.27857543
35MKNK21.25671103
36CDK81.25070441
37PASK1.23540712
38MAPKAPK51.20975580
39EIF2AK21.17092774
40TNIK1.17080320
41RIPK41.14688685
42ZAK1.13640222
43BTK1.13626493
44ATR1.13555819
45RPS6KA51.13044846
46IRAK31.09331405
47LATS11.08480850
48EIF2AK31.07501357
49TTK1.05538795
50TEC1.05031557
51EEF2K1.04706775
52PINK11.04400068
53AURKB1.04191543
54PLK11.02354945
55KDR1.01643735
56ADRBK21.00494061
57DAPK10.99811313
58WNK30.97918924
59KIT0.95958183
60TSSK60.94915420
61IKBKE0.93605241
62IKBKB0.92804935
63TGFBR10.89432383
64OXSR10.89101430
65BRAF0.86991257
66AURKA0.86820831
67FLT30.85017515
68BCKDK0.84630755
69STK40.84006891
70PLK30.83973221
71GRK10.81803592
72NEK20.78384834
73NEK10.76623510
74DYRK20.76530445
75ITK0.75701394
76PRPF4B0.75482922
77FES0.75348925
78SIK20.74578289
79TXK0.73893969
80BRSK20.72853328
81CDK90.71969907
82TAF10.70927123
83CSNK1G10.70671498
84NME10.69175112
85PIM10.68401559
86CSNK2A10.68254253
87TRPM70.68221674
88TBK10.65790821
89JAK30.65342186
90CDK40.64649739
91LYN0.63849442
92PLK40.63122676
93CSNK1G20.62726937
94PIK3CG0.60839040
95CSNK2A20.59934401
96CHEK20.58047570
97MST40.57822930
98BRD40.56289242
99IRAK10.56259646
100GRK60.55316209
101RPS6KA60.55292360
102MAP3K80.54638139
103CSNK1A1L0.54395694
104PAK10.54063001
105MYLK0.53587662
106ATM0.52386178
107PLK20.51078122
108CDK30.50901998
109SYK0.50649346
110TAOK20.50026874
111CSF1R0.49619078
112PIK3CA0.49220366
113TRIM280.48357551
114ZAP700.47532583
115NLK0.47484448
116TYK20.46623084
117CHEK10.45963340
118PRKCQ0.45775711
119STK100.45369327
120LCK0.44896153
121MAPK110.44280685
122MAPK130.44253193
123NEK90.43510507
124MAPKAPK20.43125950
125BMPR1B0.42966354
126DAPK20.41320574
127RPS6KL10.40935904
128RPS6KC10.40935904
129CSNK1G30.40096075
130BMPR20.39923580
131PHKG10.39081519
132PHKG20.39081519
133IRAK20.37750510
134OBSCN0.37278671
135INSRR0.35260964

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.77229652
2Ribosome_Homo sapiens_hsa030104.69651465
3Mismatch repair_Homo sapiens_hsa034303.94150474
4Proteasome_Homo sapiens_hsa030503.40249327
5RNA polymerase_Homo sapiens_hsa030203.29051209
6Homologous recombination_Homo sapiens_hsa034403.09074698
7Base excision repair_Homo sapiens_hsa034103.02503353
8Spliceosome_Homo sapiens_hsa030402.78773850
9Nucleotide excision repair_Homo sapiens_hsa034202.76611393
10Pyrimidine metabolism_Homo sapiens_hsa002402.65099602
11Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.35662533
12Protein export_Homo sapiens_hsa030602.19046520
13Oxidative phosphorylation_Homo sapiens_hsa001902.18848516
14Non-homologous end-joining_Homo sapiens_hsa034502.13715430
15Fanconi anemia pathway_Homo sapiens_hsa034602.12644077
16Parkinsons disease_Homo sapiens_hsa050122.10597929
17Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.08310153
18One carbon pool by folate_Homo sapiens_hsa006701.77480856
19RNA transport_Homo sapiens_hsa030131.70126629
20Basal transcription factors_Homo sapiens_hsa030221.69567438
21Cell cycle_Homo sapiens_hsa041101.62103753
22Huntingtons disease_Homo sapiens_hsa050161.62041448
23RNA degradation_Homo sapiens_hsa030181.58771670
24Purine metabolism_Homo sapiens_hsa002301.57856830
25Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.50548926
26Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.40382099
27Type I diabetes mellitus_Homo sapiens_hsa049401.36119780
28Butanoate metabolism_Homo sapiens_hsa006501.34438881
29Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.33597192
30Folate biosynthesis_Homo sapiens_hsa007901.31980878
31Propanoate metabolism_Homo sapiens_hsa006401.29093658
32Alzheimers disease_Homo sapiens_hsa050101.27403442
33Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.26406033
34Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.13857226
35Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.05531221
36Primary immunodeficiency_Homo sapiens_hsa053400.99246850
37Herpes simplex infection_Homo sapiens_hsa051680.98696570
38Sulfur relay system_Homo sapiens_hsa041220.96561968
39Peroxisome_Homo sapiens_hsa041460.92822010
40Fatty acid elongation_Homo sapiens_hsa000620.89541080
41Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.87468251
42Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.87394913
43Systemic lupus erythematosus_Homo sapiens_hsa053220.85467427
44Selenocompound metabolism_Homo sapiens_hsa004500.83952572
45Phototransduction_Homo sapiens_hsa047440.83574528
46Intestinal immune network for IgA production_Homo sapiens_hsa046720.83480637
47Caffeine metabolism_Homo sapiens_hsa002320.82016760
48Arachidonic acid metabolism_Homo sapiens_hsa005900.81858628
49Tryptophan metabolism_Homo sapiens_hsa003800.81303335
50Epstein-Barr virus infection_Homo sapiens_hsa051690.80834739
51Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.80481744
52p53 signaling pathway_Homo sapiens_hsa041150.80012423
53Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.78978186
54Glutathione metabolism_Homo sapiens_hsa004800.77564188
55Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.73208014
56Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.71337926
57mRNA surveillance pathway_Homo sapiens_hsa030150.71272434
58NF-kappa B signaling pathway_Homo sapiens_hsa040640.71134152
59Antigen processing and presentation_Homo sapiens_hsa046120.70720851
60Hematopoietic cell lineage_Homo sapiens_hsa046400.69291152
61Pentose phosphate pathway_Homo sapiens_hsa000300.66469936
62Legionellosis_Homo sapiens_hsa051340.65550368
63SNARE interactions in vesicular transport_Homo sapiens_hsa041300.64719672
64Asthma_Homo sapiens_hsa053100.62535591
65Measles_Homo sapiens_hsa051620.60794431
66Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.59064066
67Allograft rejection_Homo sapiens_hsa053300.57748779
68Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.56071073
69Metabolic pathways_Homo sapiens_hsa011000.55176028
70Staphylococcus aureus infection_Homo sapiens_hsa051500.54082852
71Primary bile acid biosynthesis_Homo sapiens_hsa001200.52827050
72Cyanoamino acid metabolism_Homo sapiens_hsa004600.51223332
73Drug metabolism - other enzymes_Homo sapiens_hsa009830.49851207
74Rheumatoid arthritis_Homo sapiens_hsa053230.49613511
75Chemical carcinogenesis_Homo sapiens_hsa052040.49438460
76RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.47187157
77alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.46780479
78Collecting duct acid secretion_Homo sapiens_hsa049660.46667828
79Cardiac muscle contraction_Homo sapiens_hsa042600.46436913
80Nitrogen metabolism_Homo sapiens_hsa009100.46315826
81Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.45915554
82Autoimmune thyroid disease_Homo sapiens_hsa053200.45886415
83Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.45646792
84Maturity onset diabetes of the young_Homo sapiens_hsa049500.44789441
85Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.42414199
86Other glycan degradation_Homo sapiens_hsa005110.42144181
87NOD-like receptor signaling pathway_Homo sapiens_hsa046210.40656774
88Lysine degradation_Homo sapiens_hsa003100.40288145
89Cysteine and methionine metabolism_Homo sapiens_hsa002700.39831066
90Transcriptional misregulation in cancer_Homo sapiens_hsa052020.39461489
91Leishmaniasis_Homo sapiens_hsa051400.37368621
92HTLV-I infection_Homo sapiens_hsa051660.37279443
93Viral carcinogenesis_Homo sapiens_hsa052030.36348159
94Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.34662500
95N-Glycan biosynthesis_Homo sapiens_hsa005100.33869926
96Sphingolipid metabolism_Homo sapiens_hsa006000.32645039
97Fatty acid metabolism_Homo sapiens_hsa012120.32461634
98Olfactory transduction_Homo sapiens_hsa047400.32366504
99Malaria_Homo sapiens_hsa051440.31624182
100Graft-versus-host disease_Homo sapiens_hsa053320.31065425
101Apoptosis_Homo sapiens_hsa042100.30205556
102Viral myocarditis_Homo sapiens_hsa054160.29478870
103Regulation of autophagy_Homo sapiens_hsa041400.28793145
104Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.27159226
105Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.26650602
106Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.25574616
107Fatty acid degradation_Homo sapiens_hsa000710.25340780
108Alcoholism_Homo sapiens_hsa050340.25023097
109Influenza A_Homo sapiens_hsa051640.23417399
1102-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.22982237
111Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.22906182
112Ether lipid metabolism_Homo sapiens_hsa005650.21568232
113Pertussis_Homo sapiens_hsa051330.21505692
114Linoleic acid metabolism_Homo sapiens_hsa005910.21266449
115Jak-STAT signaling pathway_Homo sapiens_hsa046300.19511816
116Steroid biosynthesis_Homo sapiens_hsa001000.19442412
117Shigellosis_Homo sapiens_hsa051310.18496639
118Notch signaling pathway_Homo sapiens_hsa043300.17936250
119Hepatitis B_Homo sapiens_hsa051610.17037487
120B cell receptor signaling pathway_Homo sapiens_hsa046620.16853795
121Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.16472009
122Arginine and proline metabolism_Homo sapiens_hsa003300.15042991
123Galactose metabolism_Homo sapiens_hsa000520.11591819
124Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.11223226
125Thyroid cancer_Homo sapiens_hsa052160.10587601
126Toll-like receptor signaling pathway_Homo sapiens_hsa046200.08139377
127Basal cell carcinoma_Homo sapiens_hsa052170.07543537
128Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.06565426
129Carbon metabolism_Homo sapiens_hsa012000.06029857
130Biosynthesis of amino acids_Homo sapiens_hsa012300.05996168

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