OLFML2A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1metanephric mesenchyme development (GO:0072075)6.56526835
2atrioventricular valve morphogenesis (GO:0003181)6.54371362
3protein heterotrimerization (GO:0070208)6.16585965
4cell proliferation involved in metanephros development (GO:0072203)6.00819898
5cell migration involved in heart development (GO:0060973)5.92047961
6epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)5.90450924
7kidney mesenchyme development (GO:0072074)5.89631233
8endocardial cushion morphogenesis (GO:0003203)5.83560800
9vascular endothelial growth factor signaling pathway (GO:0038084)5.67177507
10cell proliferation involved in kidney development (GO:0072111)5.38323741
11glomerular filtration (GO:0003094)5.30044325
12retina vasculature morphogenesis in camera-type eye (GO:0061299)5.25613046
13positive regulation of phosphoprotein phosphatase activity (GO:0032516)5.10134433
14glomerulus development (GO:0032835)5.04397021
15positive regulation of calcium ion import (GO:0090280)4.93031884
16renal filtration (GO:0097205)4.92933349
17muscle filament sliding (GO:0030049)4.84417691
18actin-myosin filament sliding (GO:0033275)4.84417691
19mesenchyme morphogenesis (GO:0072132)4.77208566
20endothelium development (GO:0003158)4.37585290
21cGMP-mediated signaling (GO:0019934)4.33868745
22smooth muscle tissue development (GO:0048745)4.32921804
23glycoprotein catabolic process (GO:0006516)4.31555860
24actin-mediated cell contraction (GO:0070252)4.30231247
25activation of MAPKKK activity (GO:0000185)4.26614477
26extracellular fibril organization (GO:0043206)4.14567387
27mesenchymal cell development (GO:0014031)4.06701329
28positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517)4.03309363
29positive regulation of smooth muscle cell migration (GO:0014911)4.02677335
30cellular response to vascular endothelial growth factor stimulus (GO:0035924)3.98557233
31aorta morphogenesis (GO:0035909)3.94595476
32relaxation of smooth muscle (GO:0044557)3.91620788
33plasma membrane repair (GO:0001778)3.89861632
34muscle cell migration (GO:0014812)3.86215627
35regulation of integrin-mediated signaling pathway (GO:2001044)3.85300534
36cardiac epithelial to mesenchymal transition (GO:0060317)3.84940042
37myofibril assembly (GO:0030239)3.83380739
38regulation of axon extension involved in axon guidance (GO:0048841)3.80912017
39positive regulation of metanephros development (GO:0072216)3.76219452
40germ cell migration (GO:0008354)3.74947476
41basement membrane organization (GO:0071711)3.71837553
42endodermal cell differentiation (GO:0035987)3.67989036
43regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.67264742
44negative regulation of homotypic cell-cell adhesion (GO:0034111)3.63558761
45sarcomere organization (GO:0045214)3.59734736
46negative regulation of protein localization to cell surface (GO:2000009)3.55758236
47endothelial cell morphogenesis (GO:0001886)3.51472349
48skin morphogenesis (GO:0043589)3.49961299
49positive regulation of DNA biosynthetic process (GO:2000573)3.49915595
50positive regulation of monocyte chemotaxis (GO:0090026)3.46584861
51peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)3.41876451
52heart valve morphogenesis (GO:0003179)3.41746649
53regulation of skeletal muscle contraction (GO:0014819)3.41565772
54positive regulation of signal transduction by p53 class mediator (GO:1901798)3.40268478
55negative regulation of chondrocyte differentiation (GO:0032331)3.38566308
56stem cell development (GO:0048864)3.37444195
57regulation of axon guidance (GO:1902667)3.36822268
58positive regulation of vascular permeability (GO:0043117)3.33296867
59fibril organization (GO:0097435)3.31821787
60myoblast fusion (GO:0007520)3.31129321
61skeletal muscle contraction (GO:0003009)3.30344965
62collagen fibril organization (GO:0030199)3.29219455
63tonic smooth muscle contraction (GO:0014820)3.28549429
64regulation of endothelial cell differentiation (GO:0045601)3.26839541
65negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.26677075
66glomerular basement membrane development (GO:0032836)3.23352390
67macroautophagy (GO:0016236)3.22766642
68actin filament-based movement (GO:0030048)3.19477600
69regulation of calcium ion import (GO:0090279)3.18825873
70actomyosin structure organization (GO:0031032)3.18594315
71regulation of cellular extravasation (GO:0002691)3.16714968
72lymph vessel development (GO:0001945)3.16035632
73striated muscle atrophy (GO:0014891)3.11743488
74patterning of blood vessels (GO:0001569)3.11642779
75cellular response to BMP stimulus (GO:0071773)3.11210689
76response to BMP (GO:0071772)3.11210689
77muscle cell fate commitment (GO:0042693)3.08176254
78regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.07262290
79keratan sulfate catabolic process (GO:0042340)3.07073209
80import into cell (GO:0098657)3.06265674
81hemidesmosome assembly (GO:0031581)3.05979628
82muscle cell cellular homeostasis (GO:0046716)3.04840439
83lymphangiogenesis (GO:0001946)3.04426903
84response to stimulus involved in regulation of muscle adaptation (GO:0014874)3.04085056
85histamine transport (GO:0051608)3.03621218
86negative regulation of nitric-oxide synthase activity (GO:0051001)3.03007495
87regulation of metanephros development (GO:0072215)3.01888003
88extracellular matrix assembly (GO:0085029)3.01760501
89enteric nervous system development (GO:0048484)2.99429282
90negative regulation of platelet activation (GO:0010544)2.99000795
91collagen metabolic process (GO:0032963)2.98960360
92syncytium formation by plasma membrane fusion (GO:0000768)2.98038322
93response to inactivity (GO:0014854)2.97310508
94positive regulation of odontogenesis (GO:0042482)2.95976054
95collagen catabolic process (GO:0030574)2.94719968
96cardiac myofibril assembly (GO:0055003)2.94420535
97nephron tubule development (GO:0072080)2.93704749
98skeletal muscle tissue development (GO:0007519)2.93645415
99negative regulation of cartilage development (GO:0061037)2.92862042
100Notch receptor processing (GO:0007220)2.91785235
101chondrocyte proliferation (GO:0035988)2.87985975
102sprouting angiogenesis (GO:0002040)2.87333213
103platelet-derived growth factor receptor signaling pathway (GO:0048008)2.87206750
104peripheral nervous system axon ensheathment (GO:0032292)2.86980309
105myelination in peripheral nervous system (GO:0022011)2.86980309
106regulation of cardiac muscle cell differentiation (GO:2000725)2.84584832
107extracellular matrix disassembly (GO:0022617)2.83091279
108multicellular organismal macromolecule metabolic process (GO:0044259)2.81233493
109sequestering of extracellular ligand from receptor (GO:0035581)2.81013286
110cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.80890518
111positive regulation of endothelial cell apoptotic process (GO:2000353)2.78575675
112heart morphogenesis (GO:0003007)2.76094885
113nephron epithelium development (GO:0072009)2.76006246
114muscle organ development (GO:0007517)2.75523065
115bone trabecula formation (GO:0060346)2.75361806
116regulation of monocyte chemotaxis (GO:0090025)2.74679603
117iron ion import (GO:0097286)2.74390464
118neural crest cell development (GO:0014032)2.73432980
119multicellular organismal catabolic process (GO:0044243)2.72433915
120artery smooth muscle contraction (GO:0014824)2.71779108
121striated muscle contraction (GO:0006941)2.71759951
122dermatan sulfate biosynthetic process (GO:0030208)2.71742521
123renal tubule development (GO:0061326)2.71700581
124myoblast migration (GO:0051451)2.71137124
125negative regulation of receptor activity (GO:2000272)2.70292788
126negative regulation of gluconeogenesis (GO:0045721)2.70125895
127response to gravity (GO:0009629)2.69951954
128muscle structure development (GO:0061061)2.68693284
129negative regulation of potassium ion transmembrane transport (GO:1901380)2.68366508
130desmosome organization (GO:0002934)2.68115566
131outflow tract morphogenesis (GO:0003151)2.67502699
132histamine secretion (GO:0001821)2.67164104
133positive regulation of astrocyte differentiation (GO:0048711)2.66611683
134* extracellular matrix organization (GO:0030198)2.66132963
135regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.65274882
136multicellular organismal metabolic process (GO:0044236)2.65250493
137* extracellular structure organization (GO:0043062)2.65143742
138positive regulation of phosphatase activity (GO:0010922)2.65138237
139muscle atrophy (GO:0014889)2.64740677
140regulation of smooth muscle cell migration (GO:0014910)2.64256544
141muscle tissue development (GO:0060537)2.62756917
142glomerular visceral epithelial cell development (GO:0072015)2.62001394
143virion attachment to host cell (GO:0019062)2.61782730
144adhesion of symbiont to host cell (GO:0044650)2.61782730
145axon extension involved in axon guidance (GO:0048846)2.61655951
146neuron projection extension involved in neuron projection guidance (GO:1902284)2.61655951
147muscle cell proliferation (GO:0033002)2.61205013
148cell-substrate junction assembly (GO:0007044)2.61067671
149positive regulation of kidney development (GO:0090184)2.60250178
150regulation of sarcomere organization (GO:0060297)2.58388352
151regulation of transforming growth factor beta2 production (GO:0032909)2.57911281
152response to muscle activity (GO:0014850)2.57803191
153dermatan sulfate metabolic process (GO:0030205)2.57526212
154vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.55951107
155cardiac muscle contraction (GO:0060048)2.55722532
156cell-matrix adhesion (GO:0007160)2.55233943
157vascular smooth muscle contraction (GO:0014829)2.55026622
158cardiac ventricle morphogenesis (GO:0003208)2.54518408
159substrate adhesion-dependent cell spreading (GO:0034446)2.54387816
160induction of positive chemotaxis (GO:0050930)2.52639791
161ganglion development (GO:0061548)2.52278813
162response to hyperoxia (GO:0055093)2.48993875
163response to increased oxygen levels (GO:0036296)2.48993875
164positive regulation of catecholamine secretion (GO:0033605)2.48662702
165cardiac chamber morphogenesis (GO:0003206)2.47591290

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human4.03201072
2TP63_17297297_ChIP-ChIP_HaCaT_Human2.89120249
3TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.48372816
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.47428135
5* ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.36260638
6SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.35867313
7EED_16625203_ChIP-ChIP_MESCs_Mouse2.34981341
8SMAD_19615063_ChIP-ChIP_OVARY_Human2.32613555
9PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.24170983
10SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.17701912
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.09975414
12SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.09731779
13WT1_19549856_ChIP-ChIP_CCG9911_Human2.04684404
14EP300_21415370_ChIP-Seq_HL-1_Mouse2.03269099
15CLOCK_20551151_ChIP-Seq_293T_Human2.02531514
16STAT6_21828071_ChIP-Seq_BEAS2B_Human1.99930795
17EZH2_18974828_ChIP-Seq_MESCs_Mouse1.99586695
18RNF2_18974828_ChIP-Seq_MESCs_Mouse1.99586695
19CDX2_19796622_ChIP-Seq_MESCs_Mouse1.99458453
20* CJUN_26792858_Chip-Seq_BT549_Human1.88240306
21ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.85389542
22KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.83303011
23KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.83303011
24KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.83303011
25GBX2_23144817_ChIP-Seq_PC3_Human1.82220661
26RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.81727396
27ESR2_21235772_ChIP-Seq_MCF-7_Human1.80088219
28PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.78105919
29EZH2_22144423_ChIP-Seq_EOC_Human1.73719062
30JARID2_20075857_ChIP-Seq_MESCs_Mouse1.73484190
31MTF2_20144788_ChIP-Seq_MESCs_Mouse1.73090105
32ZNF217_24962896_ChIP-Seq_MCF-7_Human1.71658537
33ESR1_21235772_ChIP-Seq_MCF-7_Human1.68746562
34EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.68004960
35TP53_18474530_ChIP-ChIP_U2OS_Human1.67497863
36JARID2_20064375_ChIP-Seq_MESCs_Mouse1.66997781
37* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.64981323
38* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.62584879
39EZH2_27304074_Chip-Seq_ESCs_Mouse1.61752137
40GATA2_21666600_ChIP-Seq_HMVEC_Human1.59595938
41SUZ12_27294783_Chip-Seq_ESCs_Mouse1.58355054
42AR_21572438_ChIP-Seq_LNCaP_Human1.58230278
43CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.57351221
44TP53_16413492_ChIP-PET_HCT116_Human1.53820213
45PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.48444102
46SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.47451934
47* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.46607336
48EZH2_27294783_Chip-Seq_ESCs_Mouse1.46302167
49FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.46272504
50CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.45808179
51RNF2_27304074_Chip-Seq_ESCs_Mouse1.45803531
52* RARG_19884340_ChIP-ChIP_MEFs_Mouse1.45550077
53PIAS1_25552417_ChIP-Seq_VCAP_Human1.44549612
54FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.39987322
55ESR1_20079471_ChIP-ChIP_T-47D_Human1.36691779
56* SMC3_22415368_ChIP-Seq_MEFs_Mouse1.29757915
57ARNT_22903824_ChIP-Seq_MCF-7_Human1.29577220
58SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.29148308
59AHR_22903824_ChIP-Seq_MCF-7_Human1.28428692
60SOX9_24532713_ChIP-Seq_HFSC_Mouse1.24871583
61STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.24739164
62BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.24157276
63NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.19272759
64NRF2_20460467_ChIP-Seq_MEFs_Mouse1.19272759
65TP53_23651856_ChIP-Seq_MEFs_Mouse1.16231958
66JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.16202549
67THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.15549919
68GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15138278
69IKZF1_21737484_ChIP-ChIP_HCT116_Human1.13684884
70PPAR_26484153_Chip-Seq_NCI-H1993_Human1.12125713
71AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.11871609
72NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.11123968
73* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.10757455
74DROSHA_22980978_ChIP-Seq_HELA_Human1.09912933
75FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.09529548
76CBX2_27304074_Chip-Seq_ESCs_Mouse1.08494731
77NR3C1_21868756_ChIP-Seq_MCF10A_Human1.07221981
78CTNNB1_20460455_ChIP-Seq_HCT116_Human1.07208692
79TCF4_18268006_ChIP-ChIP_LS174T_Human1.07183367
80* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.07022999
81TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.06706414
82BRD4_25478319_ChIP-Seq_HGPS_Human1.06685627
83TP53_20018659_ChIP-ChIP_R1E_Mouse1.06597510
84RING1B_27294783_Chip-Seq_ESCs_Mouse1.05403235
85CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.05209383
86MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.04790177
87SMC1_22415368_ChIP-Seq_MEFs_Mouse1.04436181
88SOX2_20726797_ChIP-Seq_SW620_Human1.04363436
89BMI1_23680149_ChIP-Seq_NPCS_Mouse1.04128537
90NFIB_24661679_ChIP-Seq_LUNG_Mouse1.03826547
91IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.03430576
92SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.03148299
93TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.00466362
94SMAD3_21741376_ChIP-Seq_HESCs_Human1.00285487
95* P300_19829295_ChIP-Seq_ESCs_Human0.99655485
96* ISL1_27105846_Chip-Seq_CPCs_Mouse0.99407491
97SMAD3_21741376_ChIP-Seq_EPCs_Human0.99019648
98* RING1B_27294783_Chip-Seq_NPCs_Mouse0.98268941
99TP63_23658742_ChIP-Seq_EP156T_Human0.97925628
100JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.97177328
101PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.96782119
102SMAD4_21799915_ChIP-Seq_A2780_Human0.95712206
103GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.95225926
104P63_26484246_Chip-Seq_KERATINOCYTES_Human0.94585131
105SA1_22415368_ChIP-Seq_MEFs_Mouse0.94227192
106CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.93897711
107* PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.93841278
108KDM2B_26808549_Chip-Seq_REH_Human0.93241704
109ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.92894680
110PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.92531187
111ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.91806620
112SMAD4_21741376_ChIP-Seq_HESCs_Human0.90695463
113ZFP57_27257070_Chip-Seq_ESCs_Mouse0.90356513
114AR_25329375_ChIP-Seq_VCAP_Human0.90024520
115* NFI_21473784_ChIP-Seq_ESCs_Mouse0.89290861
116RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.88589588
117TBX20_22328084_ChIP-Seq_HEART_Mouse0.86793805
118TBX20_22080862_ChIP-Seq_HEART_Mouse0.86793805
119NR3C1_23031785_ChIP-Seq_PC12_Mouse0.86580291
120TOP2B_26459242_ChIP-Seq_MCF-7_Human0.85836685
121BCAT_22108803_ChIP-Seq_LS180_Human0.85262507
122* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.84151753
123* SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.83921663
124* SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.83921663

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004272_abnormal_basement_membrane5.82871355
2MP0003279_aneurysm4.80652666
3MP0008438_abnormal_cutaneous_collagen3.50624833
4MP0009278_abnormal_bone_marrow3.13479524
5MP0005503_abnormal_tendon_morphology3.01137668
6MP0003705_abnormal_hypodermis_morpholog2.95647873
7MP0003724_increased_susceptibility_to2.83662136
8MP0000767_abnormal_smooth_muscle2.68967240
9MP0005257_abnormal_intraocular_pressure2.64529725
10MP0004084_abnormal_cardiac_muscle2.47547305
11MP0002254_reproductive_system_inflammat2.44732532
12MP0010368_abnormal_lymphatic_system2.37703229
13MP0005623_abnormal_meninges_morphology2.34622324
14MP0001879_abnormal_lymphatic_vessel2.32852077
15MP0005165_increased_susceptibility_to2.29099251
16MP0006054_spinal_hemorrhage2.28042512
17MP0001958_emphysema2.27301010
18MP0000751_myopathy2.09511523
19MP0005164_abnormal_response_to2.02535537
20MP0005595_abnormal_vascular_smooth2.02387816
21MP0000013_abnormal_adipose_tissue2.00563852
22MP0005171_absent_coat_pigmentation1.99788412
23MP0004087_abnormal_muscle_fiber1.98266599
24MP0005508_abnormal_skeleton_morphology1.97318279
25MP0005275_abnormal_skin_tensile1.90565655
26MP0003828_pulmonary_edema1.82934423
27MP0001542_abnormal_bone_strength1.82503408
28MP0010030_abnormal_orbit_morphology1.77068450
29MP0000759_abnormal_skeletal_muscle1.64389867
30MP0004036_abnormal_muscle_relaxation1.63271570
31MP0009780_abnormal_chondrocyte_physiolo1.63236232
32MP0002269_muscular_atrophy1.62692641
33MP0004883_abnormal_blood_vessel1.61752494
34MP0000462_abnormal_digestive_system1.60264028
35MP0003091_abnormal_cell_migration1.58944633
36MP0002295_abnormal_pulmonary_circulatio1.57872767
37MP0005369_muscle_phenotype1.57595180
38MP0002106_abnormal_muscle_physiology1.53727720
39MP0004145_abnormal_muscle_electrophysio1.53104884
40MP0002009_preneoplasia1.50055258
41MP0005330_cardiomyopathy1.49748162
42MP0000762_abnormal_tongue_morphology1.48862480
43MP0005367_renal/urinary_system_phenotyp1.46812672
44MP0000516_abnormal_urinary_system1.46812672
45MP0002108_abnormal_muscle_morphology1.46617033
46MP0003045_fibrosis1.44083369
47MP0001346_abnormal_lacrimal_gland1.43877598
48MP0009250_abnormal_appendicular_skeleto1.43558566
49MP0003385_abnormal_body_wall1.41830121
50MP0003283_abnormal_digestive_organ1.41478823
51MP0005023_abnormal_wound_healing1.40013183
52MP0001661_extended_life_span1.36664083
53MP0002060_abnormal_skin_morphology1.35378188
54MP0004858_abnormal_nervous_system1.33937741
55MP0003566_abnormal_cell_adhesion1.26495216
56MP0000733_abnormal_muscle_development1.21892196
57MP0009384_cardiac_valve_regurgitation1.21213663
58MP0000049_abnormal_middle_ear1.20558419
59MP0002128_abnormal_blood_circulation1.16821512
60MP0000003_abnormal_adipose_tissue1.15220524
61MP0002837_dystrophic_cardiac_calcinosis1.13701216
62MP0002938_white_spotting1.13573032
63MP0003941_abnormal_skin_development1.12951185
64MP0005620_abnormal_muscle_contractility1.12174999
65MP0000749_muscle_degeneration1.10878477
66MP0005390_skeleton_phenotype1.07747278
67MP0009379_abnormal_foot_pigmentation1.06121898
68MP0003075_altered_response_to1.05138999
69MP0000747_muscle_weakness1.03644161
70MP0000613_abnormal_salivary_gland1.03319440
71MP0001614_abnormal_blood_vessel1.02521887
72MP0000534_abnormal_ureter_morphology1.02151575
73MP0010630_abnormal_cardiac_muscle1.01424789
74MP0004134_abnormal_chest_morphology1.00385057
75MP0004185_abnormal_adipocyte_glucose0.99305532
76MP0002896_abnormal_bone_mineralization0.96702681
77MP0000579_abnormal_nail_morphology0.96668872
78MP0003137_abnormal_impulse_conducting0.96435750
79MP0002932_abnormal_joint_morphology0.93869774
80MP0008775_abnormal_heart_ventricle0.93458909
81MP0000383_abnormal_hair_follicle0.92943590
82MP0000163_abnormal_cartilage_morphology0.92699817
83MP0001270_distended_abdomen0.91462146
84MP0002925_abnormal_cardiovascular_devel0.90739904
85MP0006138_congestive_heart_failure0.90561417
86MP0003935_abnormal_craniofacial_develop0.89981585
87MP0000249_abnormal_blood_vessel0.88484418
88MP0002133_abnormal_respiratory_system0.88350839
89MP0005388_respiratory_system_phenotype0.88350839
90MP0003115_abnormal_respiratory_system0.87909809
91MP0000750_abnormal_muscle_regeneration0.87837750
92MP0002233_abnormal_nose_morphology0.87644439
93MP0002249_abnormal_larynx_morphology0.87575004
94MP0000343_altered_response_to0.87547699
95MP0004130_abnormal_muscle_cell0.86806083
96MP0000230_abnormal_systemic_arterial0.86121976
97MP0005670_abnormal_white_adipose0.85997632
98MP0005167_abnormal_blood-brain_barrier0.83873663
99MP0002933_joint_inflammation0.82301598
100MP0003950_abnormal_plasma_membrane0.82108258
101MP0004484_altered_response_of0.81324741
102MP0000538_abnormal_urinary_bladder0.79327850
103MP0005397_hematopoietic_system_phenotyp0.78887908
104MP0001545_abnormal_hematopoietic_system0.78887908
105MP0003942_abnormal_urinary_system0.78684178
106MP0002166_altered_tumor_susceptibility0.78673915
107MP0000647_abnormal_sebaceous_gland0.78545054
108MP0001544_abnormal_cardiovascular_syste0.78436708
109MP0005385_cardiovascular_system_phenoty0.78436708
110MP0009764_decreased_sensitivity_to0.78029524
111MP0002127_abnormal_cardiovascular_syste0.78017294
112MP0003755_abnormal_palate_morphology0.75914277
113MP0005375_adipose_tissue_phenotype0.74904688
114MP0001299_abnormal_eye_distance/0.74495568
115MP0004215_abnormal_myocardial_fiber0.73685426
116MP0002972_abnormal_cardiac_muscle0.72479273
117MP0005187_abnormal_penis_morphology0.72266766
118MP0004085_abnormal_heartbeat0.71848421
119MP0001851_eye_inflammation0.71586383
120MP0002098_abnormal_vibrissa_morphology0.71278658
121MP0000566_synostosis0.71101235
122MP0004233_abnormal_muscle_weight0.69720173
123MP0003448_altered_tumor_morphology0.69385047
124MP0001915_intracranial_hemorrhage0.68926877
125MP0002115_abnormal_skeleton_extremities0.68640153
126MP0002168_other_aberrant_phenotype0.67759940
127MP0002114_abnormal_axial_skeleton0.66627512
128MP0000432_abnormal_head_morphology0.64668615
129MP0000467_abnormal_esophagus_morphology0.64588956
130MP0002177_abnormal_outer_ear0.64141417
131MP0001243_abnormal_dermal_layer0.64081723
132MP0002116_abnormal_craniofacial_bone0.63185795
133MP0009053_abnormal_anal_canal0.60734039
134MP0000266_abnormal_heart_morphology0.58214045
135MP0002113_abnormal_skeleton_development0.56877523
136MP0000858_altered_metastatic_potential0.56875528
137MP0002234_abnormal_pharynx_morphology0.55837135
138MP0010771_integument_phenotype0.53365720

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)5.66048176
2Popliteal pterygium (HP:0009756)5.55692051
3Aortic dissection (HP:0002647)5.13857287
4Protrusio acetabuli (HP:0003179)4.78715482
5Atrophic scars (HP:0001075)4.65739789
6Aortic aneurysm (HP:0004942)4.63551887
7Short hallux (HP:0010109)4.62489226
8Ankle contracture (HP:0006466)4.62034600
9Distal arthrogryposis (HP:0005684)4.60408518
10Bone cyst (HP:0012062)4.57777306
11Round ear (HP:0100830)4.54525483
12Cerebellar dysplasia (HP:0007033)4.46669004
13Aplasia/Hypoplasia of the hallux (HP:0008362)4.18400559
14Gowers sign (HP:0003391)4.09538281
15Neonatal short-limb short stature (HP:0008921)4.08544352
16Type II lissencephaly (HP:0007260)3.98266133
17Abnormality of dentin (HP:0010299)3.97685392
18Difficulty climbing stairs (HP:0003551)3.92656711
19Broad metatarsal (HP:0001783)3.90742613
20Amniotic constriction ring (HP:0009775)3.89066676
21Abnormality of placental membranes (HP:0011409)3.89066676
22Retinal atrophy (HP:0001105)3.88825582
23Type 1 muscle fiber predominance (HP:0003803)3.85916479
24Follicular hyperkeratosis (HP:0007502)3.76851833
25Fetal akinesia sequence (HP:0001989)3.75012887
26Cerebral aneurysm (HP:0004944)3.64785586
27Ulnar deviation of the wrist (HP:0003049)3.63521621
28Aplasia of the musculature (HP:0100854)3.59514747
29Buphthalmos (HP:0000557)3.51595260
30Fragile skin (HP:0001030)3.44006915
31Calcaneovalgus deformity (HP:0001848)3.43130104
32Pulmonary artery stenosis (HP:0004415)3.35976420
33Fatigable weakness (HP:0003473)3.32221979
34Abnormality of the neuromuscular junction (HP:0003398)3.32221979
35Abnormality of Sharpey fibers (HP:0100685)3.30226832
36Chondrocalcinosis (HP:0000934)3.27536702
37Retinal dysplasia (HP:0007973)3.25097543
38Type 2 muscle fiber atrophy (HP:0003554)3.16604872
39Soft skin (HP:0000977)3.12260391
40Nemaline bodies (HP:0003798)3.11674647
41Venous insufficiency (HP:0005293)3.09761608
42Pterygium (HP:0001059)3.07641196
43Malignant hyperthermia (HP:0002047)3.06335963
44Spinal rigidity (HP:0003306)3.03816884
45Fatigue (HP:0012378)3.02126555
46Increased connective tissue (HP:0009025)2.94246587
47Morphological abnormality of the middle ear (HP:0008609)2.93165949
48Thin ribs (HP:0000883)2.83552163
49Venous abnormality (HP:0002624)2.82111672
50Hypoplasia of the iris (HP:0007676)2.73563899
51Ulnar claw (HP:0001178)2.73069706
52Muscle fiber atrophy (HP:0100295)2.72154079
53Aortic regurgitation (HP:0001659)2.70339270
54Bladder diverticulum (HP:0000015)2.69133212
55Hypoplasia of the pons (HP:0012110)2.69071681
56Absent phalangeal crease (HP:0006109)2.66976469
57Hip contracture (HP:0003273)2.66657333
58Increased variability in muscle fiber diameter (HP:0003557)2.66573893
59Aplasia/Hypoplasia involving the musculature (HP:0001460)2.65331761
60Neoplasm of the lung (HP:0100526)2.63965790
61Mesomelia (HP:0003027)2.62533857
62Mildly elevated creatine phosphokinase (HP:0008180)2.61560300
63Pseudobulbar signs (HP:0002200)2.60483296
64Wormian bones (HP:0002645)2.59476212
65Akinesia (HP:0002304)2.59254197
66Nonimmune hydrops fetalis (HP:0001790)2.57885030
67Limited hip movement (HP:0008800)2.57844506
68Muscle fiber inclusion bodies (HP:0100299)2.57230757
69Biconcave vertebral bodies (HP:0004586)2.56394231
70Slender build (HP:0001533)2.55181022
71Congenital glaucoma (HP:0001087)2.44658568
72Absent toe (HP:0010760)2.43551919
73Femoral bowing (HP:0002980)2.42494478
74Peritonitis (HP:0002586)2.41913558
75Abnormality of the pons (HP:0007361)2.41296876
76Megalocornea (HP:0000485)2.40196218
77Trismus (HP:0000211)2.40049235
78Right ventricular cardiomyopathy (HP:0011663)2.39535097
79Abnormality of skeletal muscle fiber size (HP:0012084)2.39067717
80Deformed tarsal bones (HP:0008119)2.38153652
81Dilatation of the ascending aorta (HP:0005111)2.37680962
82Hyporeflexia of lower limbs (HP:0002600)2.36584110
83Calf muscle hypertrophy (HP:0008981)2.35754874
84Shallow orbits (HP:0000586)2.34343284
85Aplasia cutis congenita (HP:0001057)2.34158374
86Vascular tortuosity (HP:0004948)2.33669693
87Infantile muscular hypotonia (HP:0008947)2.33618500
88Hypercalcemia (HP:0003072)2.33478342
89Generalized muscle weakness (HP:0003324)2.32655615
90Sudden death (HP:0001699)2.29634303
91Congenital, generalized hypertrichosis (HP:0004540)2.28335322
92Aplasia/Hypoplasia affecting the retina (HP:0008061)2.27523424
93Fibular hypoplasia (HP:0003038)2.26862371
94Gingival overgrowth (HP:0000212)2.26861370
95Hypoplastic ischia (HP:0003175)2.26460558
96Prominent supraorbital ridges (HP:0000336)2.26232755
97Abnormality of the ischium (HP:0003174)2.23196217
98Weak cry (HP:0001612)2.22130306
99Submucous cleft hard palate (HP:0000176)2.20211528
100Segmental peripheral demyelination/remyelination (HP:0003481)2.16960633
101Adactyly (HP:0009776)2.16691802
102Upper limb muscle weakness (HP:0003484)2.16410213
103Aneurysm (HP:0002617)2.14631426
104Abnormality of the calcaneus (HP:0008364)2.14542872
105Neoplasm of the respiratory system (HP:0100606)2.14100485
106Abnormal finger flexion creases (HP:0006143)2.11103081
107Muscular dystrophy (HP:0003560)2.10288718
108Osteolytic defects of the hand bones (HP:0009699)2.09003548
109Osteolytic defects of the phalanges of the hand (HP:0009771)2.09003548
110Scapular winging (HP:0003691)2.06745331
111Lipoatrophy (HP:0100578)2.06420705
112Cervical subluxation (HP:0003308)2.05243453
113Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.05147054
114Easy fatigability (HP:0003388)2.04980326
115Stroke (HP:0001297)2.04840114
116Muscle hypertrophy of the lower extremities (HP:0008968)2.04515510
117Preaxial foot polydactyly (HP:0001841)2.03397945
118Wrist flexion contracture (HP:0001239)2.02067010
119Benign neoplasm of the central nervous system (HP:0100835)2.00178895
120Decreased electroretinogram (ERG) amplitude (HP:0000654)1.99206791
121Tibial bowing (HP:0002982)1.96725397
122Arterial tortuosity (HP:0005116)1.96686581
123Mild short stature (HP:0003502)1.96651928
124Breech presentation (HP:0001623)1.96597111
125Entropion (HP:0000621)1.95494309
126Distal lower limb amyotrophy (HP:0008944)1.93935013
127Narrow nasal bridge (HP:0000446)1.93810264
128Metatarsus adductus (HP:0001840)1.93727327
129Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.91924096
130Short 4th metacarpal (HP:0010044)1.91924096
131Asymmetric septal hypertrophy (HP:0001670)1.91717278
132Bowel diverticulosis (HP:0005222)1.91391169
133Mitral valve prolapse (HP:0001634)1.90104803
134Mesangial abnormality (HP:0001966)1.89693726
135Ectopia lentis (HP:0001083)1.88466276
136Wide anterior fontanel (HP:0000260)1.87793026
137Neck muscle weakness (HP:0000467)1.87633600
138Distal lower limb muscle weakness (HP:0009053)1.87575725
139Craniofacial hyperostosis (HP:0004493)1.86920958
140Knee flexion contracture (HP:0006380)1.85742335
141Genu recurvatum (HP:0002816)1.85211232
142Keratoconus (HP:0000563)1.84852725
143Increased corneal curvature (HP:0100692)1.84852725
144Joint laxity (HP:0001388)1.84750654
145Delayed gross motor development (HP:0002194)1.84402488
146Blue sclerae (HP:0000592)1.84117453
147Muscle fiber splitting (HP:0003555)1.82256996
148Broad hallux (HP:0010055)1.80777642
149Abnormality of the calf musculature (HP:0001430)1.79682541
150Milia (HP:0001056)1.79468811
151Humeroradial synostosis (HP:0003041)1.78950670
152Synostosis involving the elbow (HP:0003938)1.78950670
153Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.78814627
154Abnormality of the phalanges of the 2nd finger (HP:0009541)1.77155237
155Ventricular tachycardia (HP:0004756)1.71448050
156Cranial hyperostosis (HP:0004437)1.70526789
157Stomach cancer (HP:0012126)1.70009763
158Generalized amyotrophy (HP:0003700)1.69381619
159Abnormal delivery (HP:0001787)1.68669941
160Hyperextensible skin (HP:0000974)1.66837886

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MYLK5.73191659
2PDGFRA4.42897811
3KIT4.42885940
4EPHA33.33596529
5STK103.21380042
6TTN3.16814158
7TIE13.02353578
8EPHB22.89763815
9DMPK2.88989157
10MARK32.88939307
11ZAK2.68891205
12FGFR42.41060268
13LIMK12.30964785
14EPHB12.18864065
15MAPK152.14755081
16MAPKAPK32.04282497
17TGFBR21.85881542
18PDGFRB1.85366764
19FRK1.83771447
20PAK21.81540749
21CDC42BPA1.75125082
22DDR21.61288622
23FER1.60121985
24BMPR1B1.56099540
25KDR1.47379187
26PIK3CG1.46907895
27ABL21.46872355
28IRAK11.44431713
29EEF2K1.39358016
30PIK3CA1.37018439
31TGFBR11.34497220
32MST1R1.32715052
33EPHA21.32388137
34RIPK11.31014858
35ADRBK11.30989002
36STK111.28327090
37FGFR21.27907053
38TRIB31.26423564
39PRKD21.25036703
40FGFR31.23795068
41MAP2K21.17507688
42MET1.15585889
43NUAK11.14529925
44LATS21.10740276
45ROCK11.04460441
46NLK1.03509005
47ILK1.00205612
48LATS10.99726836
49MUSK0.98912123
50TESK10.94903946
51MELK0.93077057
52MAP3K70.91471937
53INSRR0.89682370
54TRPM70.87687879
55ERN10.86179996
56MAP2K10.81133326
57PTK2B0.79747519
58MAPK70.79581478
59NEK90.79259450
60CAMK10.79112743
61GRK10.73200919
62PAK40.69261261
63MAP3K140.68940971
64CLK10.68873641
65MAPKAPK50.66197180
66CASK0.66043958
67MARK10.65499466
68STK380.64322251
69DAPK30.63500019
70PRKCE0.63377760
71PIM10.61161109
72JAK10.61116516
73NEK60.61089398
74ERBB30.61044961
75ADRBK20.60990063
76LMTK20.60030595
77ERBB20.59999410
78FLT30.58020417
79CDK80.57814083
80TSSK60.57267060
81CDK90.56646976
82PTK20.56590143
83HIPK20.55821097
84CAMK2D0.55692057
85CCNB10.55360187
86PRKCH0.54163841
87OBSCN0.53871275
88INSR0.53533776
89PNCK0.53362238
90STK30.51009737
91PTK60.50634017
92RPS6KA20.47645444
93CAMK2G0.46772725
94MTOR0.46714072
95STK390.46254937
96CAMK1D0.45935504
97SIK10.45346433
98STK38L0.44968074
99PRKD30.44083758
100MAP3K60.43569605
101JAK30.43309495
102PRKAA20.42753015
103CAMK1G0.41855974
104CAMK2A0.40965748
105ABL10.40860273
106ROCK20.39953378
107ERBB40.38598301
108RET0.38540215
109CDK30.36856963
110RPS6KA40.36308036
111GSK3A0.35805270
112MAP3K20.35178534
113CAMK40.34349265
114MAP3K30.33259511
115CAMK2B0.33167611
116MAPK40.31033681
117PHKG10.30563866
118PHKG20.30563866
119IGF1R0.30133741
120WNK10.29615701
121IRAK30.28688460
122PRKD10.28037790
123SGK4940.27353317
124SGK2230.27353317
125MOS0.26924364
126IKBKE0.26912030
127BCR0.26228946
128AKT30.25756135
129IRAK20.25745927
130PRKG20.24693319
131MAPK120.24097360
132RPS6KL10.24036955
133RPS6KC10.24036955
134MAPKAPK20.22805646
135TYK20.22804727
136PAK30.22269867
137EIF2AK20.22227457
138NTRK10.21467204

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045124.34880441
2Focal adhesion_Homo sapiens_hsa045102.96435518
3Dorso-ventral axis formation_Homo sapiens_hsa043202.71192512
4Protein digestion and absorption_Homo sapiens_hsa049742.67500697
5Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.56538691
6Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.14477130
7Dilated cardiomyopathy_Homo sapiens_hsa054142.13097030
8Amoebiasis_Homo sapiens_hsa051462.04179395
9Notch signaling pathway_Homo sapiens_hsa043301.91618874
10Vascular smooth muscle contraction_Homo sapiens_hsa042701.89776483
11AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.82512272
12Cardiac muscle contraction_Homo sapiens_hsa042601.78194994
13Malaria_Homo sapiens_hsa051441.71707626
14Adherens junction_Homo sapiens_hsa045201.69094748
15Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.66974763
16PI3K-Akt signaling pathway_Homo sapiens_hsa041511.55583456
17Leukocyte transendothelial migration_Homo sapiens_hsa046701.55342193
18TGF-beta signaling pathway_Homo sapiens_hsa043501.54465705
19Axon guidance_Homo sapiens_hsa043601.48817991
20Toxoplasmosis_Homo sapiens_hsa051451.42088368
21Small cell lung cancer_Homo sapiens_hsa052221.40332627
22Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.38499643
23cGMP-PKG signaling pathway_Homo sapiens_hsa040221.37565254
24Thyroid hormone synthesis_Homo sapiens_hsa049181.36673807
25Hippo signaling pathway_Homo sapiens_hsa043901.34583933
26MicroRNAs in cancer_Homo sapiens_hsa052061.34045315
27Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.33636295
28Regulation of actin cytoskeleton_Homo sapiens_hsa048101.33473427
29Renin secretion_Homo sapiens_hsa049241.32016558
30Melanoma_Homo sapiens_hsa052181.28491658
31Pathways in cancer_Homo sapiens_hsa052001.26743882
32African trypanosomiasis_Homo sapiens_hsa051431.26430134
33Rap1 signaling pathway_Homo sapiens_hsa040151.23089097
34Gap junction_Homo sapiens_hsa045401.17551839
35Tight junction_Homo sapiens_hsa045301.17016674
36Intestinal immune network for IgA production_Homo sapiens_hsa046721.16664344
37Prostate cancer_Homo sapiens_hsa052151.15848041
38Platelet activation_Homo sapiens_hsa046111.14549964
39Proteoglycans in cancer_Homo sapiens_hsa052051.13884868
40Circadian rhythm_Homo sapiens_hsa047101.13318938
41Basal cell carcinoma_Homo sapiens_hsa052171.12656758
42Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.07794721
43Rheumatoid arthritis_Homo sapiens_hsa053231.02961508
44Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.02167310
45Viral myocarditis_Homo sapiens_hsa054161.01315022
46NF-kappa B signaling pathway_Homo sapiens_hsa040641.00375738
47Ras signaling pathway_Homo sapiens_hsa040140.99702373
48Choline metabolism in cancer_Homo sapiens_hsa052310.98812329
49cAMP signaling pathway_Homo sapiens_hsa040240.98371340
50Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.98271280
51TNF signaling pathway_Homo sapiens_hsa046680.96186939
52SNARE interactions in vesicular transport_Homo sapiens_hsa041300.95012972
53Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.93649193
54MAPK signaling pathway_Homo sapiens_hsa040100.92863656
55Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.90671130
56Insulin secretion_Homo sapiens_hsa049110.84449214
57Leishmaniasis_Homo sapiens_hsa051400.84160354
58Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.83978757
59Hedgehog signaling pathway_Homo sapiens_hsa043400.83680524
60Calcium signaling pathway_Homo sapiens_hsa040200.82913822
61Phospholipase D signaling pathway_Homo sapiens_hsa040720.81867419
62Ovarian steroidogenesis_Homo sapiens_hsa049130.81602069
63Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.80084249
64Glucagon signaling pathway_Homo sapiens_hsa049220.80003840
65Salivary secretion_Homo sapiens_hsa049700.78771619
66Glioma_Homo sapiens_hsa052140.77339786
67Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.77206218
68PPAR signaling pathway_Homo sapiens_hsa033200.77123615
69Sulfur relay system_Homo sapiens_hsa041220.77094283
70Estrogen signaling pathway_Homo sapiens_hsa049150.77050477
71Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.77001716
72Pertussis_Homo sapiens_hsa051330.73723183
73Phototransduction_Homo sapiens_hsa047440.71691670
74Melanogenesis_Homo sapiens_hsa049160.70269579
75AMPK signaling pathway_Homo sapiens_hsa041520.70238247
76Oxytocin signaling pathway_Homo sapiens_hsa049210.69983315
77Osteoclast differentiation_Homo sapiens_hsa043800.69793263
78Wnt signaling pathway_Homo sapiens_hsa043100.69102817
79Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.67533330
80Mineral absorption_Homo sapiens_hsa049780.67337215
81Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.65060785
82HTLV-I infection_Homo sapiens_hsa051660.64401368
83Cyanoamino acid metabolism_Homo sapiens_hsa004600.64348601
84Thyroid hormone signaling pathway_Homo sapiens_hsa049190.62721057
85Toll-like receptor signaling pathway_Homo sapiens_hsa046200.62492024
86alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.61188647
87Circadian entrainment_Homo sapiens_hsa047130.60896632
88Salmonella infection_Homo sapiens_hsa051320.60602558
89Sulfur metabolism_Homo sapiens_hsa009200.59491484
90Histidine metabolism_Homo sapiens_hsa003400.58874404
91Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.58265266
92Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.57502563
93Gastric acid secretion_Homo sapiens_hsa049710.57409434
94Renal cell carcinoma_Homo sapiens_hsa052110.53546361
95Jak-STAT signaling pathway_Homo sapiens_hsa046300.53143209
96ABC transporters_Homo sapiens_hsa020100.51248286
97Chemokine signaling pathway_Homo sapiens_hsa040620.51242370
98Adipocytokine signaling pathway_Homo sapiens_hsa049200.51120213
99Glycerolipid metabolism_Homo sapiens_hsa005610.50528672
100Prion diseases_Homo sapiens_hsa050200.49783550
101Hepatitis B_Homo sapiens_hsa051610.49604759
102Linoleic acid metabolism_Homo sapiens_hsa005910.49270261
103Longevity regulating pathway - mammal_Homo sapiens_hsa042110.49244423
104Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.48235278
105Arachidonic acid metabolism_Homo sapiens_hsa005900.46695635
106Transcriptional misregulation in cancer_Homo sapiens_hsa052020.46419058
107Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.45700623
108Hepatitis C_Homo sapiens_hsa051600.44512737
109Bile secretion_Homo sapiens_hsa049760.44507874
110Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.43859545
111Influenza A_Homo sapiens_hsa051640.43661426
112Hematopoietic cell lineage_Homo sapiens_hsa046400.43358151
113Pancreatic cancer_Homo sapiens_hsa052120.43181676
114Glycosaminoglycan degradation_Homo sapiens_hsa005310.42348194
115Apoptosis_Homo sapiens_hsa042100.41828729
116Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.41718367
117Nitrogen metabolism_Homo sapiens_hsa009100.41127578
118Pancreatic secretion_Homo sapiens_hsa049720.40294358
119Prolactin signaling pathway_Homo sapiens_hsa049170.39904705
120Chronic myeloid leukemia_Homo sapiens_hsa052200.37907304
121Aldosterone synthesis and secretion_Homo sapiens_hsa049250.37642647
122Endometrial cancer_Homo sapiens_hsa052130.37413783
123Cocaine addiction_Homo sapiens_hsa050300.35946041
124Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.35481615
125Insulin resistance_Homo sapiens_hsa049310.35200190
126Long-term depression_Homo sapiens_hsa047300.35115922
127Renin-angiotensin system_Homo sapiens_hsa046140.35107135
128Ether lipid metabolism_Homo sapiens_hsa005650.34641043
129Bladder cancer_Homo sapiens_hsa052190.31442101
130Cholinergic synapse_Homo sapiens_hsa047250.30460257
131Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.27555514
132Tryptophan metabolism_Homo sapiens_hsa003800.27234530
133Serotonergic synapse_Homo sapiens_hsa047260.26508670

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