NUP155

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)6.17213387
2nuclear pore organization (GO:0006999)6.06638497
3DNA unwinding involved in DNA replication (GO:0006268)5.27773633
4protein localization to kinetochore (GO:0034501)5.14316239
5mitotic sister chromatid cohesion (GO:0007064)4.89380756
6pore complex assembly (GO:0046931)4.66019909
7* mitotic nuclear envelope disassembly (GO:0007077)4.41895667
8DNA double-strand break processing (GO:0000729)4.41025741
9mitotic chromosome condensation (GO:0007076)4.36238649
10DNA replication-dependent nucleosome organization (GO:0034723)4.33609400
11DNA replication-dependent nucleosome assembly (GO:0006335)4.33609400
12protein localization to chromosome, centromeric region (GO:0071459)4.31133511
13sister chromatid segregation (GO:0000819)4.26706253
14regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.26336617
15DNA replication initiation (GO:0006270)4.23283217
16kinetochore organization (GO:0051383)4.16187408
17* nuclear envelope disassembly (GO:0051081)4.13280144
18* membrane disassembly (GO:0030397)4.13280144
19mitotic metaphase plate congression (GO:0007080)4.12255099
20mitotic sister chromatid segregation (GO:0000070)4.10014573
21IMP biosynthetic process (GO:0006188)4.06735761
22DNA duplex unwinding (GO:0032508)4.04414321
23folic acid-containing compound biosynthetic process (GO:0009396)4.04339226
24DNA geometric change (GO:0032392)4.03629144
25non-recombinational repair (GO:0000726)4.02950852
26double-strand break repair via nonhomologous end joining (GO:0006303)4.02950852
27DNA strand elongation involved in DNA replication (GO:0006271)3.99567526
28pre-miRNA processing (GO:0031054)3.91662655
29regulation of histone H3-K9 methylation (GO:0051570)3.91433664
30regulation of spindle organization (GO:0090224)3.90943342
31replication fork processing (GO:0031297)3.85698599
32regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.84756273
33metaphase plate congression (GO:0051310)3.82099672
34DNA strand elongation (GO:0022616)3.80269547
35negative regulation of histone methylation (GO:0031061)3.68507032
36regulation of sister chromatid cohesion (GO:0007063)3.64358122
37heterochromatin organization (GO:0070828)3.63240624
38regulation of centrosome duplication (GO:0010824)3.59426979
39positive regulation of chromosome segregation (GO:0051984)3.59031716
40nucleobase biosynthetic process (GO:0046112)3.58739514
41chromatin remodeling at centromere (GO:0031055)3.58155162
42telomere maintenance via semi-conservative replication (GO:0032201)3.57239282
43dosage compensation (GO:0007549)3.54995734
44regulation of RNA export from nucleus (GO:0046831)3.54570869
45IMP metabolic process (GO:0046040)3.53423738
46regulation of mitotic spindle organization (GO:0060236)3.52433008
47DNA replication checkpoint (GO:0000076)3.52119038
48mitotic recombination (GO:0006312)3.50575459
49chromatin assembly (GO:0031497)3.49153537
50negative regulation of DNA-dependent DNA replication (GO:2000104)3.49087481
51attachment of spindle microtubules to kinetochore (GO:0008608)3.47633583
52CENP-A containing nucleosome assembly (GO:0034080)3.46652199
53regulation of DNA endoreduplication (GO:0032875)3.45628693
54DNA replication-independent nucleosome organization (GO:0034724)3.45173583
55DNA replication-independent nucleosome assembly (GO:0006336)3.45173583
56positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.43848134
57positive regulation of mitotic sister chromatid separation (GO:1901970)3.43848134
58positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.43848134
59chromatin assembly or disassembly (GO:0006333)3.43163343
60regulation of translational fidelity (GO:0006450)3.42637513
61maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.40171230
62kinetochore assembly (GO:0051382)3.39412367
63regulation of centriole replication (GO:0046599)3.39307727
64postreplication repair (GO:0006301)3.39286552
65DNA conformation change (GO:0071103)3.37098420
66regulation of centrosome cycle (GO:0046605)3.36621397
67meiotic chromosome segregation (GO:0045132)3.35230534
68telomere maintenance via recombination (GO:0000722)3.34903349
69regulation of chromosome segregation (GO:0051983)3.34791337
70establishment of chromosome localization (GO:0051303)3.34538248
71DNA topological change (GO:0006265)3.34327629
72microtubule depolymerization (GO:0007019)3.32473016
73spindle checkpoint (GO:0031577)3.31515407
74protein localization to chromosome (GO:0034502)3.30945058
75regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.26129111
76somatic diversification of immune receptors via somatic mutation (GO:0002566)3.25747719
77somatic hypermutation of immunoglobulin genes (GO:0016446)3.25747719
78spindle assembly checkpoint (GO:0071173)3.25066637
79regulation of mitotic metaphase/anaphase transition (GO:0030071)3.24510385
80DNA ligation (GO:0006266)3.23229391
81regulation of mitotic spindle checkpoint (GO:1903504)3.21427217
82regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.21427217
83translesion synthesis (GO:0019985)3.19804441
84negative regulation of chromosome segregation (GO:0051985)3.19792272
85purine nucleobase biosynthetic process (GO:0009113)3.19391207
86DNA catabolic process, exonucleolytic (GO:0000738)3.18759210
87* nuclear envelope organization (GO:0006998)3.17501745
88synapsis (GO:0007129)3.16633875
89regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.15846355
90regulation of posttranscriptional gene silencing (GO:0060147)3.15384521
91regulation of gene silencing by miRNA (GO:0060964)3.15384521
92regulation of gene silencing by RNA (GO:0060966)3.15384521
93mitotic spindle checkpoint (GO:0071174)3.14746797
94mitotic spindle assembly checkpoint (GO:0007094)3.14092337
95histone exchange (GO:0043486)3.14090759
96negative regulation of mitotic sister chromatid segregation (GO:0033048)3.13125133
97negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.13125133
98negative regulation of sister chromatid segregation (GO:0033046)3.13125133
99negative regulation of mitotic sister chromatid separation (GO:2000816)3.13125133
100chromosome condensation (GO:0030261)3.10950154
101regulation of nuclear cell cycle DNA replication (GO:0033262)3.10801497
102regulation of helicase activity (GO:0051095)3.10394616
103telomere maintenance (GO:0000723)3.09949832
104telomere maintenance via telomere lengthening (GO:0010833)3.09028090
105negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.08818472
106telomere organization (GO:0032200)3.07536784
107DNA synthesis involved in DNA repair (GO:0000731)3.06665307
108chromosome segregation (GO:0007059)3.06261321
109sister chromatid cohesion (GO:0007062)3.06060852
110regulation of mitotic sister chromatid separation (GO:0010965)3.05929928
111regulation of mitotic sister chromatid segregation (GO:0033047)3.05929928
112regulation of sister chromatid segregation (GO:0033045)3.05929928
113protein K6-linked ubiquitination (GO:0085020)3.05050044
114formation of translation preinitiation complex (GO:0001731)3.04900297
115nucleotide-excision repair, DNA gap filling (GO:0006297)3.04686006
116negative regulation of DNA repair (GO:0045738)3.04559312
117regulation of DNA-dependent DNA replication (GO:0090329)3.04299886
118ATP-dependent chromatin remodeling (GO:0043044)3.03955141
119DNA packaging (GO:0006323)3.03666203
120ribosome assembly (GO:0042255)3.02374693
121negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.02247719

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.86066021
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.60435689
3* MYC_18555785_ChIP-Seq_MESCs_Mouse3.68279978
4FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.60591250
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.08489860
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.03437925
7* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.87767282
8MYC_19079543_ChIP-ChIP_MESCs_Mouse2.72623633
9EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.68331436
10AR_21909140_ChIP-Seq_LNCAP_Human2.54709018
11* E2F1_21310950_ChIP-Seq_MCF-7_Human2.52598405
12* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.50042583
13SALL1_21062744_ChIP-ChIP_HESCs_Human2.31198375
14NELFA_20434984_ChIP-Seq_ESCs_Mouse2.27853429
15RBPJ_22232070_ChIP-Seq_NCS_Mouse2.20810948
16MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.15872114
17* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.08511298
18* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.03759787
19E2F7_22180533_ChIP-Seq_HELA_Human11.3164320
20MYC_22102868_ChIP-Seq_BL_Human1.93501948
21MYCN_18555785_ChIP-Seq_MESCs_Mouse1.89266117
22* XRN2_22483619_ChIP-Seq_HELA_Human1.85091544
23* EST1_17652178_ChIP-ChIP_JURKAT_Human1.78002952
24TP63_19390658_ChIP-ChIP_HaCaT_Human1.77594954
25CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.72685953
26SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.71222233
27POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.70631352
28HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.67365720
29CREB1_15753290_ChIP-ChIP_HEK293T_Human1.67057877
30KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.65581928
31EWS_26573619_Chip-Seq_HEK293_Human1.63607640
32* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.61635751
33PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.59931328
34FUS_26573619_Chip-Seq_HEK293_Human1.56407257
35* VDR_23849224_ChIP-Seq_CD4+_Human1.53968199
36NANOG_18555785_ChIP-Seq_MESCs_Mouse1.53476188
37NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.52310931
38ELK1_19687146_ChIP-ChIP_HELA_Human1.52289650
39* ETS1_20019798_ChIP-Seq_JURKAT_Human1.51967526
40CIITA_25753668_ChIP-Seq_RAJI_Human1.51391278
41FOXP3_21729870_ChIP-Seq_TREG_Human1.51041796
42KDM5A_27292631_Chip-Seq_BREAST_Human1.49812566
43POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.46219242
44HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.42059813
45ZFX_18555785_ChIP-Seq_MESCs_Mouse1.41533887
46TTF2_22483619_ChIP-Seq_HELA_Human1.41338054
47E2F1_18555785_ChIP-Seq_MESCs_Mouse1.40755916
48SOX2_18555785_ChIP-Seq_MESCs_Mouse1.39858085
49NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.39489973
50ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.36363819
51MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.32579162
52DCP1A_22483619_ChIP-Seq_HELA_Human1.30011230
53* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.27253856
54* GABP_17652178_ChIP-ChIP_JURKAT_Human1.26004114
55* GABP_19822575_ChIP-Seq_HepG2_Human1.23104565
56STAT3_1855785_ChIP-Seq_MESCs_Mouse1.21522268
57* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.18137565
58POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.17996681
59TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.17023421
60HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.15599807
61HOXB4_20404135_ChIP-ChIP_EML_Mouse1.14696403
62NOTCH1_21737748_ChIP-Seq_TLL_Human1.14548551
63E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.14183864
64ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.14113832
65THAP11_20581084_ChIP-Seq_MESCs_Mouse1.13831864
66KLF4_18555785_ChIP-Seq_MESCs_Mouse1.13822615
67* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.13576286
68CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.12752637
69SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.12493561
70ZNF274_21170338_ChIP-Seq_K562_Hela1.12160529
71POU3F2_20337985_ChIP-ChIP_501MEL_Human1.10847688
72FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.10253218
73* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.09506388
74DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.09169594
75NANOG_21062744_ChIP-ChIP_HESCs_Human1.08849482
76ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.08790333
77* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.08165834
78TFEB_21752829_ChIP-Seq_HELA_Human1.06887100
79E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.06531269
80KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.06275176
81TCF3_18692474_ChIP-Seq_MEFs_Mouse1.03318439
82SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.02523938
83SRF_21415370_ChIP-Seq_HL-1_Mouse1.02378770
84ELF1_17652178_ChIP-ChIP_JURKAT_Human1.02086434
85* POU5F1_16153702_ChIP-ChIP_HESCs_Human1.01632657
86TCF3_18692474_ChIP-Seq_MESCs_Mouse1.00044323
87* ESR1_15608294_ChIP-ChIP_MCF-7_Human0.98865973
88PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.98830090
89CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.97975044
90ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.95040888
91IGF1R_20145208_ChIP-Seq_DFB_Human0.94656200
92KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.93950875
93KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.93950875
94KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.93950875
95CHD1_26751641_Chip-Seq_LNCaP_Human0.93875131
96SOX17_20123909_ChIP-Seq_XEN_Mouse0.92163543
97* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.90606458
98KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.87134527
99* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.86834121
100* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.86553381
101* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.85430289
102VDR_21846776_ChIP-Seq_THP-1_Human0.84225740
103NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.84055847
104ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.83869631
105DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.83513379
106BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.82738277
107PKCTHETA_26484144_Chip-Seq_BREAST_Human0.82219688
108NANOG_16153702_ChIP-ChIP_HESCs_Human0.79515236
109VDR_22108803_ChIP-Seq_LS180_Human0.79280014
110RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.78311939
111TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.78082290
112NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.76810726
113HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.74649163
114SOX2_16153702_ChIP-ChIP_HESCs_Human0.74375633
115ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.74167768
116TAF15_26573619_Chip-Seq_HEK293_Human0.73972601
117* MYC_18940864_ChIP-ChIP_HL60_Human0.73389026
118HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.69550556
119PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.68736117
120CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.65819875
121* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.65035966
122SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.64862849
123SOX9_26525672_Chip-Seq_HEART_Mouse0.64729847
124YY1_21170310_ChIP-Seq_MESCs_Mouse0.64137519
125FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.62334284
126BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.61455255
127IRF1_19129219_ChIP-ChIP_H3396_Human0.60203817

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability4.31634386
2MP0003111_abnormal_nucleus_morphology4.01473596
3MP0003693_abnormal_embryo_hatching3.96399514
4MP0008057_abnormal_DNA_replication3.96142810
5MP0003077_abnormal_cell_cycle3.49518044
6MP0004957_abnormal_blastocyst_morpholog3.47273385
7MP0010352_gastrointestinal_tract_polyps3.04607156
8MP0008058_abnormal_DNA_repair2.61914816
9MP0010307_abnormal_tumor_latency2.52552251
10MP0003123_paternal_imprinting2.49005465
11MP0008007_abnormal_cellular_replicative2.41061291
12MP0001730_embryonic_growth_arrest2.38698078
13MP0009697_abnormal_copulation2.27131615
14MP0003705_abnormal_hypodermis_morpholog2.26990674
15MP0000350_abnormal_cell_proliferation2.25842916
16MP0005076_abnormal_cell_differentiation2.23221524
17MP0008932_abnormal_embryonic_tissue2.14688822
18MP0002396_abnormal_hematopoietic_system2.12886237
19MP0001672_abnormal_embryogenesis/_devel2.00811590
20MP0005380_embryogenesis_phenotype2.00811590
21MP0003121_genomic_imprinting2.00016409
22MP0002009_preneoplasia1.99135626
23MP0003890_abnormal_embryonic-extraembry1.97302703
24MP0004197_abnormal_fetal_growth/weight/1.95633548
25MP0008877_abnormal_DNA_methylation1.92875214
26MP0002084_abnormal_developmental_patter1.90718244
27MP0003984_embryonic_growth_retardation1.85600931
28MP0000372_irregular_coat_pigmentation1.84436653
29MP0002088_abnormal_embryonic_growth/wei1.83693226
30MP0001697_abnormal_embryo_size1.82765917
31MP0002085_abnormal_embryonic_tissue1.78431527
32MP0002086_abnormal_extraembryonic_tissu1.75793727
33MP0001293_anophthalmia1.71706126
34MP0000537_abnormal_urethra_morphology1.70742834
35MP0009053_abnormal_anal_canal1.69525149
36MP0006292_abnormal_olfactory_placode1.68339603
37MP0003567_abnormal_fetal_cardiomyocyte1.58938642
38MP0010030_abnormal_orbit_morphology1.58472335
39* MP0002080_prenatal_lethality1.58216071
40MP0001661_extended_life_span1.57791155
41MP0004808_abnormal_hematopoietic_stem1.54619551
42MP0003136_yellow_coat_color1.53616773
43MP0000569_abnormal_digit_pigmentation1.51357490
44MP0003786_premature_aging1.44687132
45MP0003937_abnormal_limbs/digits/tail_de1.36457108
46MP0002102_abnormal_ear_morphology1.36168275
47MP0005171_absent_coat_pigmentation1.29129889
48MP0009672_abnormal_birth_weight1.28886520
49MP0000490_abnormal_crypts_of1.28322843
50MP0009703_decreased_birth_body1.26775684
51MP0002234_abnormal_pharynx_morphology1.25735432
52MP0000313_abnormal_cell_death1.20663929
53MP0003119_abnormal_digestive_system1.18069950
54MP0002092_abnormal_eye_morphology1.16159378
55MP0002697_abnormal_eye_size1.14728120
56MP0002019_abnormal_tumor_incidence1.13840390
57MP0000428_abnormal_craniofacial_morphol1.12151864
58MP0006054_spinal_hemorrhage1.12090220
59MP0005408_hypopigmentation1.12087526
60MP0000733_abnormal_muscle_development1.08957933
61MP0001915_intracranial_hemorrhage1.08340848
62MP0003566_abnormal_cell_adhesion1.07970752
63MP0003115_abnormal_respiratory_system1.04741878
64MP0000647_abnormal_sebaceous_gland1.00213560
65MP0003935_abnormal_craniofacial_develop0.99673858
66MP0002111_abnormal_tail_morphology0.99331858
67MP0002210_abnormal_sex_determination0.99132315
68MP0000432_abnormal_head_morphology0.96197120
69MP0005023_abnormal_wound_healing0.94440325
70MP0010234_abnormal_vibrissa_follicle0.92699811
71MP0001286_abnormal_eye_development0.92635981
72MP0006072_abnormal_retinal_apoptosis0.92579411
73MP0003646_muscle_fatigue0.92297958
74MP0001145_abnormal_male_reproductive0.89169609
75MP0002925_abnormal_cardiovascular_devel0.88742631
76MP0002877_abnormal_melanocyte_morpholog0.87804772
77MP0009278_abnormal_bone_marrow0.87333479
78MP0002938_white_spotting0.86269364
79MP0001849_ear_inflammation0.86188933
80MP0000703_abnormal_thymus_morphology0.86089226
81MP0000358_abnormal_cell_content/0.84977181
82MP0006035_abnormal_mitochondrial_morpho0.84628726
83MP0000427_abnormal_hair_cycle0.84226316
84MP0005397_hematopoietic_system_phenotyp0.83943925
85MP0001545_abnormal_hematopoietic_system0.83943925
86MP0005391_vision/eye_phenotype0.83487227
87MP0003943_abnormal_hepatobiliary_system0.82965239
88MP0002233_abnormal_nose_morphology0.82376160
89MP0000631_abnormal_neuroendocrine_gland0.82093473
90MP0000015_abnormal_ear_pigmentation0.80360831
91MP0003698_abnormal_male_reproductive0.79333942
92MP0003315_abnormal_perineum_morphology0.78048012
93MP0004264_abnormal_extraembryonic_tissu0.77625660
94MP0003941_abnormal_skin_development0.77214226
95MP0002095_abnormal_skin_pigmentation0.76987578
96MP0003755_abnormal_palate_morphology0.76850241
97MP0005253_abnormal_eye_physiology0.75283104
98MP0003787_abnormal_imprinting0.74382914
99MP0005621_abnormal_cell_physiology0.73904337
100MP0005384_cellular_phenotype0.73717432
101MP0000653_abnormal_sex_gland0.73115876
102MP0005174_abnormal_tail_pigmentation0.71853091
103MP0001346_abnormal_lacrimal_gland0.71620641
104MP0001929_abnormal_gametogenesis0.71434303
105MP0003861_abnormal_nervous_system0.70617545
106MP0003385_abnormal_body_wall0.70610143
107MP0000383_abnormal_hair_follicle0.69726252
108MP0001324_abnormal_eye_pigmentation0.69654019
109MP0008995_early_reproductive_senescence0.69174532
110MP0003806_abnormal_nucleotide_metabolis0.68783773
111MP0005395_other_phenotype0.68340960
112MP0005187_abnormal_penis_morphology0.68174759
113MP0010678_abnormal_skin_adnexa0.68071894
114MP0002932_abnormal_joint_morphology0.67211363
115MP0002751_abnormal_autonomic_nervous0.66950229
116MP0003718_maternal_effect0.66576805
117MP0000266_abnormal_heart_morphology0.65887722
118MP0001119_abnormal_female_reproductive0.65559164
119MP0002161_abnormal_fertility/fecundity0.64044876
120MP0002090_abnormal_vision0.62893921
121MP0003699_abnormal_female_reproductive0.62753733
122MP0008770_decreased_survivor_rate0.62632397
123MP0004233_abnormal_muscle_weight0.61914083
124MP0005367_renal/urinary_system_phenotyp0.61133715
125MP0000516_abnormal_urinary_system0.61133715
126MP0002114_abnormal_axial_skeleton0.61037687
127MP0002075_abnormal_coat/hair_pigmentati0.60855050
128MP0003942_abnormal_urinary_system0.59999169
129MP0002160_abnormal_reproductive_system0.59672455
130MP0000371_diluted_coat_color0.58600471
131MP0000477_abnormal_intestine_morphology0.57825434
132MP0005248_abnormal_Harderian_gland0.56742685
133MP0002116_abnormal_craniofacial_bone0.56622986
134MP0002722_abnormal_immune_system0.55830386

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)3.86659149
2Ependymoma (HP:0002888)3.66980471
3Volvulus (HP:0002580)3.56805830
4Medulloblastoma (HP:0002885)3.55907558
5Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.53466965
6Short 4th metacarpal (HP:0010044)3.53466965
7Chromosomal breakage induced by crosslinking agents (HP:0003221)3.48711662
8Colon cancer (HP:0003003)3.34313086
9Selective tooth agenesis (HP:0001592)3.30067500
10Abnormality of chromosome stability (HP:0003220)3.10942172
11Increased nuchal translucency (HP:0010880)3.06191360
12Rhabdomyosarcoma (HP:0002859)3.01335185
13Astrocytoma (HP:0009592)2.99820718
14Abnormality of the astrocytes (HP:0100707)2.99820718
15Ectopic kidney (HP:0000086)2.98900106
16Deviation of the thumb (HP:0009603)2.93971016
17Proximal placement of thumb (HP:0009623)2.88200567
18Birth length less than 3rd percentile (HP:0003561)2.82661686
19Impulsivity (HP:0100710)2.74117848
20Clubbing of toes (HP:0100760)2.71342037
21Neoplasm of the oral cavity (HP:0100649)2.70047776
22Abnormality of the labia minora (HP:0012880)2.67849126
23Glioma (HP:0009733)2.66880574
24Abnormal number of incisors (HP:0011064)2.56955672
25Neoplasm of striated muscle (HP:0009728)2.51042873
26Agnosia (HP:0010524)2.50741367
27Reticulocytopenia (HP:0001896)2.48162353
28Meckel diverticulum (HP:0002245)2.47685841
29Abnormality of the 4th metacarpal (HP:0010012)2.47601267
30Prominent nose (HP:0000448)2.43057252
31Patellar aplasia (HP:0006443)2.37724477
32Long eyelashes (HP:0000527)2.37647383
33Aplasia/Hypoplasia of the uvula (HP:0010293)2.37583235
34Small intestinal stenosis (HP:0012848)2.36352466
35Duodenal stenosis (HP:0100867)2.36352466
36Abnormality of the ileum (HP:0001549)2.34137723
37Biliary tract neoplasm (HP:0100574)2.33480016
38Basal cell carcinoma (HP:0002671)2.31486937
39Abnormality of the preputium (HP:0100587)2.23919257
40Myelodysplasia (HP:0002863)2.23293816
41Abnormality of cochlea (HP:0000375)2.22523230
42Absent radius (HP:0003974)2.22117953
43Aplasia/Hypoplasia of the patella (HP:0006498)2.21274999
44Atresia of the external auditory canal (HP:0000413)2.21115451
45Malignant gastrointestinal tract tumors (HP:0006749)2.20113609
46Gastrointestinal carcinoma (HP:0002672)2.20113609
47Triphalangeal thumb (HP:0001199)2.18281264
48Cafe-au-lait spot (HP:0000957)2.17197946
49High pitched voice (HP:0001620)2.16309984
50Abnormality of the fingertips (HP:0001211)2.13672982
51Cortical dysplasia (HP:0002539)2.13597722
52Neoplasm of the adrenal cortex (HP:0100641)2.11458390
53Abnormality of the anterior horn cell (HP:0006802)2.09584130
54Degeneration of anterior horn cells (HP:0002398)2.09584130
55Abnormality of the renal collecting system (HP:0004742)2.07733324
56Facial hemangioma (HP:0000329)2.07381658
57Arteriovenous malformation (HP:0100026)2.06993640
58Abnormal lung lobation (HP:0002101)2.04803064
59Absent forearm bone (HP:0003953)2.04028913
60Aplasia involving forearm bones (HP:0009822)2.04028913
61Missing ribs (HP:0000921)2.03271801
62Abnormality of the carotid arteries (HP:0005344)2.03054814
63Deep philtrum (HP:0002002)2.01577240
64Neoplasm of the pancreas (HP:0002894)2.00562681
65Choanal atresia (HP:0000453)2.00354646
66Abnormality of the duodenum (HP:0002246)2.00046652
67Short humerus (HP:0005792)1.99082789
68Sloping forehead (HP:0000340)1.97991085
69Aplasia/hypoplasia of the humerus (HP:0006507)1.97315592
70Heterotopia (HP:0002282)1.95536410
71Nephroblastoma (Wilms tumor) (HP:0002667)1.92683007
72Skull defect (HP:0001362)1.92525306
73Breast hypoplasia (HP:0003187)1.92517254
74Renal duplication (HP:0000075)1.91886280
75Aplasia/Hypoplasia of the sternum (HP:0006714)1.91093107
76Abnormality of abdominal situs (HP:0011620)1.90015568
77Abdominal situs inversus (HP:0003363)1.90015568
78Abnormality of methionine metabolism (HP:0010901)1.88951132
79Pancreatic islet-cell hyperplasia (HP:0004510)1.88246165
80Sandal gap (HP:0001852)1.87230123
81Abnormality of DNA repair (HP:0003254)1.87197977
8211 pairs of ribs (HP:0000878)1.86943099
83Embryonal neoplasm (HP:0002898)1.84817036
84Cutaneous melanoma (HP:0012056)1.84013091
85Absent thumb (HP:0009777)1.83597705
86Ovarian neoplasm (HP:0100615)1.83390208
87Rectal prolapse (HP:0002035)1.80748986
88Abnormality of glycolysis (HP:0004366)1.80560428
89Embryonal renal neoplasm (HP:0011794)1.80487776
90Microvesicular hepatic steatosis (HP:0001414)1.80483120
91Cutis marmorata (HP:0000965)1.80458017
92Facial cleft (HP:0002006)1.80192390
93Intestinal atresia (HP:0011100)1.79891327
94Neoplasm of the colon (HP:0100273)1.79453387
95Squamous cell carcinoma (HP:0002860)1.79261598
96Horseshoe kidney (HP:0000085)1.78841011
97Truncal obesity (HP:0001956)1.78565586
98Skin tags (HP:0010609)1.78446441
99Supernumerary ribs (HP:0005815)1.76910307
100Renovascular hypertension (HP:0100817)1.75873369
101Broad thumb (HP:0011304)1.75528148
102Abnormality of chromosome segregation (HP:0002916)1.75305763
103Intestinal polyp (HP:0005266)1.75252777
104Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.74638101
105Urethral obstruction (HP:0000796)1.74288671
106Short thumb (HP:0009778)1.74261665
107Duplicated collecting system (HP:0000081)1.74139378
108Bifid tongue (HP:0010297)1.72311122
109Uterine neoplasm (HP:0010784)1.72171892
110Broad palm (HP:0001169)1.71528095
111Supernumerary spleens (HP:0009799)1.71206898
112Amaurosis fugax (HP:0100576)1.71162464
113Intestinal polyposis (HP:0200008)1.71130251
114Pelvic girdle muscle weakness (HP:0003749)1.70852040
115Oral leukoplakia (HP:0002745)1.70781402
116Tracheoesophageal fistula (HP:0002575)1.70065436
117Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.68540857
118Abnormality of alanine metabolism (HP:0010916)1.68540857
119Hyperalaninemia (HP:0003348)1.68540857
120Supernumerary bones of the axial skeleton (HP:0009144)1.68279685
121Cerebellar dysplasia (HP:0007033)1.68123972
122Low anterior hairline (HP:0000294)1.68072783
123Breast carcinoma (HP:0003002)1.67673823
124Abnormality of the calcaneus (HP:0008364)1.66147977
125Aplasia/Hypoplasia of the sacrum (HP:0008517)1.64586617
126Small hand (HP:0200055)1.64487111
127Morphological abnormality of the inner ear (HP:0011390)1.63980030
128Abnormal auditory evoked potentials (HP:0006958)1.62776624
129Abnormality of the pons (HP:0007361)1.56884588
130Astigmatism (HP:0000483)1.56646330
131Ureteral duplication (HP:0000073)1.56100605
132Preaxial hand polydactyly (HP:0001177)1.54602304
133Oligodactyly (hands) (HP:0001180)1.54058478
134Hypopigmentation of the fundus (HP:0007894)1.53213225
135Partial agenesis of the corpus callosum (HP:0001338)1.52473878
136High anterior hairline (HP:0009890)1.52247065
137Hypoplasia of the pons (HP:0012110)1.50729534
138Bone marrow hypocellularity (HP:0005528)1.49427178
139Neoplasm of the adrenal gland (HP:0100631)1.47800225
140Aqueductal stenosis (HP:0002410)1.47702373
141Homocystinuria (HP:0002156)1.47333976
142Abnormality of homocysteine metabolism (HP:0010919)1.47333976
143Increased serum pyruvate (HP:0003542)1.47191716
144Neoplasm of the small intestine (HP:0100833)1.46530426
145Gastrointestinal atresia (HP:0002589)1.45930970
146Limb hypertonia (HP:0002509)1.45885122
147Single umbilical artery (HP:0001195)1.44423404

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.75415518
2CDK123.94257587
3WEE13.42213204
4NEK23.00013238
5BUB12.69352720
6TTK2.55745304
7SRPK12.47576463
8PBK2.38092244
9EEF2K2.33226613
10NEK12.23646725
11TRIM282.02314047
12ATR1.97621147
13MKNK11.91172704
14PLK11.87827530
15RPS6KB21.85421211
16BRD41.83900983
17TSSK61.78791079
18AURKB1.75862446
19BRSK21.75618035
20MAP3K101.74010991
21LATS11.72521990
22PASK1.72235222
23PLK31.71708656
24SCYL21.70350025
25TLK11.69738509
26CDK71.66645015
27ACVR1B1.66217452
28CDK41.63343270
29EIF2AK11.61299218
30BMPR1B1.60857110
31PKN21.60584767
32CHEK21.58917759
33CHEK11.51828942
34NUAK11.48202731
35TAF11.46078393
36STK101.45050513
37PLK41.41826553
38ZAK1.41028434
39PDK21.40609662
40RPS6KA41.37359631
41STK31.37080736
42EPHA21.36709376
43MKNK21.35988112
44CDK61.34854666
45ATM1.32963501
46MAP3K81.32941170
47STK41.27312920
48TGFBR11.20507665
49WNK31.20485158
50MST1R1.15579317
51ALK1.14063766
52DYRK31.13265300
53CCNB11.12213872
54MST41.12014074
55TTN1.10669641
56MTOR1.09945724
57CDK21.09248402
58MELK1.07576003
59PLK21.03659806
60PAK41.02877880
61STK391.00196133
62VRK20.97512967
63VRK10.95854987
64TNIK0.94655685
65PIM10.93615245
66FLT30.92388594
67CAMK1D0.90985111
68CDK10.87230059
69AURKA0.85170272
70BRSK10.81568666
71CSNK1G10.72706467
72EIF2AK30.72697229
73PAK20.72388737
74FGFR10.71659237
75PNCK0.67359931
76CSNK1D0.64580033
77CDK90.62401258
78WNK40.61852206
79NME10.61411089
80BCR0.61201821
81NEK90.60748692
82PRKDC0.60507560
83STK160.59968808
84CSNK1G30.59854890
85CSNK1A1L0.58980167
86PDGFRA0.58362335
87LRRK20.56866963
88ERBB40.56640696
89CSNK2A20.56325347
90SMG10.55583456
91PTK60.55201330
92CSNK1E0.55064836
93CDK30.54631313
94AKT20.51623198
95RPS6KA50.51462199
96MAPK140.51209757
97LATS20.49505212
98STK38L0.48726980
99MAPKAPK50.46158954
100RPS6KB10.46104535
101FRK0.44712743
102TESK20.44166343
103FGFR20.43741475
104EIF2AK20.42430183
105CSNK1G20.42011771
106FGFR30.41679824
107CSNK2A10.41322793
108AKT10.40611096
109RIPK10.39090025
110MAPK10.37942510
111CDK80.37478094
112GSK3B0.37294305
113BRAF0.37124263
114MAP3K40.36955758
115OXSR10.36582472
116BMX0.36191705
117MET0.36143472
118ERBB30.35588354
119PAK10.34846989
120NME20.34538314
121MAP2K30.33347777
122ICK0.33173802
123CAMK1G0.32622629
124CLK10.31302560
125CHUK0.30187217
126AKT30.30137524
127SIK10.29031421
128RAF10.27336284
129CSF1R0.26704442
130ERBB20.26024459
131TRIB30.25365130
132MAPK130.24442676

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.60216339
2Mismatch repair_Homo sapiens_hsa034304.10495152
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.46506264
4One carbon pool by folate_Homo sapiens_hsa006703.31113432
5* RNA transport_Homo sapiens_hsa030133.26380796
6Cell cycle_Homo sapiens_hsa041103.22852193
7Spliceosome_Homo sapiens_hsa030403.00916796
8Homologous recombination_Homo sapiens_hsa034402.79737611
9Base excision repair_Homo sapiens_hsa034102.74955887
10Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.61056724
11Nucleotide excision repair_Homo sapiens_hsa034202.52915293
12Fanconi anemia pathway_Homo sapiens_hsa034602.52472187
13Non-homologous end-joining_Homo sapiens_hsa034502.42522635
14Systemic lupus erythematosus_Homo sapiens_hsa053222.32035907
15mRNA surveillance pathway_Homo sapiens_hsa030152.26913267
16RNA degradation_Homo sapiens_hsa030181.90870974
17RNA polymerase_Homo sapiens_hsa030201.79444042
18p53 signaling pathway_Homo sapiens_hsa041151.76654745
19Pyrimidine metabolism_Homo sapiens_hsa002401.59675319
20Viral carcinogenesis_Homo sapiens_hsa052031.56094602
21Protein export_Homo sapiens_hsa030601.51013284
22Ribosome_Homo sapiens_hsa030101.46968832
23Basal transcription factors_Homo sapiens_hsa030221.46135640
24Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.44451103
25Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.44196312
26MicroRNAs in cancer_Homo sapiens_hsa052061.44130200
27Propanoate metabolism_Homo sapiens_hsa006401.22191976
28Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.20605020
29Selenocompound metabolism_Homo sapiens_hsa004501.19025671
30Small cell lung cancer_Homo sapiens_hsa052221.18606716
31Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.14908859
32Pyruvate metabolism_Homo sapiens_hsa006201.13316368
33Oocyte meiosis_Homo sapiens_hsa041141.12165155
34HTLV-I infection_Homo sapiens_hsa051661.11501222
35Lysine degradation_Homo sapiens_hsa003101.10281058
36Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.10280111
37Antigen processing and presentation_Homo sapiens_hsa046121.04170193
38Epstein-Barr virus infection_Homo sapiens_hsa051691.03742379
39Basal cell carcinoma_Homo sapiens_hsa052171.03674345
40Transcriptional misregulation in cancer_Homo sapiens_hsa052021.02004565
41Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.00544793
42Herpes simplex infection_Homo sapiens_hsa051681.00521722
43Alcoholism_Homo sapiens_hsa050341.00366897
44Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.99817397
45Adherens junction_Homo sapiens_hsa045200.99383302
46Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.97135119
47Steroid biosynthesis_Homo sapiens_hsa001000.97035218
48Thyroid cancer_Homo sapiens_hsa052160.92629469
49Hippo signaling pathway_Homo sapiens_hsa043900.91451495
50Chronic myeloid leukemia_Homo sapiens_hsa052200.88939873
51Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.87304296
52Colorectal cancer_Homo sapiens_hsa052100.87098235
53Proteasome_Homo sapiens_hsa030500.84820935
54TGF-beta signaling pathway_Homo sapiens_hsa043500.84533713
552-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.82132272
56Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.81028222
57Biosynthesis of amino acids_Homo sapiens_hsa012300.77300810
58Folate biosynthesis_Homo sapiens_hsa007900.75483457
59mTOR signaling pathway_Homo sapiens_hsa041500.73314601
60Purine metabolism_Homo sapiens_hsa002300.72936000
61Central carbon metabolism in cancer_Homo sapiens_hsa052300.70793447
62Fatty acid elongation_Homo sapiens_hsa000620.69123850
63Cyanoamino acid metabolism_Homo sapiens_hsa004600.68434744
64Prostate cancer_Homo sapiens_hsa052150.66025373
65Viral myocarditis_Homo sapiens_hsa054160.63994690
66Notch signaling pathway_Homo sapiens_hsa043300.63158600
67Proteoglycans in cancer_Homo sapiens_hsa052050.61519026
68Hedgehog signaling pathway_Homo sapiens_hsa043400.61426515
69Hepatitis B_Homo sapiens_hsa051610.60831515
70Cysteine and methionine metabolism_Homo sapiens_hsa002700.60250937
71Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.57585487
72Pathways in cancer_Homo sapiens_hsa052000.55744814
73Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.54512507
74Bladder cancer_Homo sapiens_hsa052190.54173776
75Huntingtons disease_Homo sapiens_hsa050160.53411501
76Apoptosis_Homo sapiens_hsa042100.52887377
77Nitrogen metabolism_Homo sapiens_hsa009100.52007167
78Endometrial cancer_Homo sapiens_hsa052130.51900923
79Fatty acid biosynthesis_Homo sapiens_hsa000610.51630339
80Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.51416029
81Non-small cell lung cancer_Homo sapiens_hsa052230.51231052
82Drug metabolism - other enzymes_Homo sapiens_hsa009830.48909390
83Thyroid hormone signaling pathway_Homo sapiens_hsa049190.48826765
84Fatty acid metabolism_Homo sapiens_hsa012120.47805965
85Butanoate metabolism_Homo sapiens_hsa006500.47347690
86Legionellosis_Homo sapiens_hsa051340.46310244
87Pancreatic cancer_Homo sapiens_hsa052120.45796040
88Wnt signaling pathway_Homo sapiens_hsa043100.45534512
89Metabolic pathways_Homo sapiens_hsa011000.43628000
90Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.41611387
91Arginine biosynthesis_Homo sapiens_hsa002200.41258183
92FoxO signaling pathway_Homo sapiens_hsa040680.40916925
93NF-kappa B signaling pathway_Homo sapiens_hsa040640.40850700
94Parkinsons disease_Homo sapiens_hsa050120.40062262
95Sulfur metabolism_Homo sapiens_hsa009200.39726328
96N-Glycan biosynthesis_Homo sapiens_hsa005100.38946111
97HIF-1 signaling pathway_Homo sapiens_hsa040660.38457726
98Glutathione metabolism_Homo sapiens_hsa004800.37325476
99Pentose phosphate pathway_Homo sapiens_hsa000300.37157011
100Melanoma_Homo sapiens_hsa052180.35977429
101Vitamin B6 metabolism_Homo sapiens_hsa007500.34220049
102Focal adhesion_Homo sapiens_hsa045100.33493794
103PI3K-Akt signaling pathway_Homo sapiens_hsa041510.32210385
104Tight junction_Homo sapiens_hsa045300.31983718
105Measles_Homo sapiens_hsa051620.31786536
106Acute myeloid leukemia_Homo sapiens_hsa052210.30322928
107Oxidative phosphorylation_Homo sapiens_hsa001900.28254686
108Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.27765583
109Sulfur relay system_Homo sapiens_hsa041220.27665477
110Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.27573489
111ECM-receptor interaction_Homo sapiens_hsa045120.26643171
112Influenza A_Homo sapiens_hsa051640.26542343
113NOD-like receptor signaling pathway_Homo sapiens_hsa046210.25423502
114Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.25086759
115Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.21953672
116Leukocyte transendothelial migration_Homo sapiens_hsa046700.21724453
117Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.21605407
118Renin-angiotensin system_Homo sapiens_hsa046140.21463094
119AMPK signaling pathway_Homo sapiens_hsa041520.20915551
120Shigellosis_Homo sapiens_hsa051310.20728969
121Neurotrophin signaling pathway_Homo sapiens_hsa047220.20637000
122Carbon metabolism_Homo sapiens_hsa012000.20132924
123Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.19115757
124Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.18721871
125Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.18432309
126Glioma_Homo sapiens_hsa052140.18130443
127Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.18097814
128Regulation of actin cytoskeleton_Homo sapiens_hsa048100.17958078
129Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.15645726
130Arginine and proline metabolism_Homo sapiens_hsa003300.15617468
131Renal cell carcinoma_Homo sapiens_hsa052110.14316567
132Pentose and glucuronate interconversions_Homo sapiens_hsa000400.14071437
133Phototransduction_Homo sapiens_hsa047440.12910316
134Tryptophan metabolism_Homo sapiens_hsa003800.12522462
135beta-Alanine metabolism_Homo sapiens_hsa004100.08500811
136Alzheimers disease_Homo sapiens_hsa050100.08202488
137Vitamin digestion and absorption_Homo sapiens_hsa049770.07134979
138Peroxisome_Homo sapiens_hsa041460.05029337

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