NPAT

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore organization (GO:0006999)4.73226373
2regulation of meiosis I (GO:0060631)4.66300961
3nuclear pore complex assembly (GO:0051292)4.59025991
4mitotic sister chromatid cohesion (GO:0007064)4.52617452
5DNA unwinding involved in DNA replication (GO:0006268)4.41123776
6piRNA metabolic process (GO:0034587)4.39062128
7central nervous system myelination (GO:0022010)4.37250728
8axon ensheathment in central nervous system (GO:0032291)4.37250728
9synapsis (GO:0007129)4.35929911
10kinetochore organization (GO:0051383)3.97939339
11regulation of centriole replication (GO:0046599)3.89413393
12positive regulation of chromosome segregation (GO:0051984)3.86122602
13regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.83753470
14mitotic metaphase plate congression (GO:0007080)3.80605318
15DNA replication initiation (GO:0006270)3.80237375
16regulation of RNA export from nucleus (GO:0046831)3.74497128
17CENP-A containing nucleosome assembly (GO:0034080)3.71994715
18mitotic chromosome condensation (GO:0007076)3.66640216
19chromatin remodeling at centromere (GO:0031055)3.66533429
20replication fork processing (GO:0031297)3.66319994
21DNA double-strand break processing (GO:0000729)3.63225812
22metaphase plate congression (GO:0051310)3.61459559
23regulation of DNA endoreduplication (GO:0032875)3.59487637
24attachment of spindle microtubules to kinetochore (GO:0008608)3.59002482
25RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.57363498
26meiotic chromosome segregation (GO:0045132)3.54505215
27phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.50034891
28positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.48193004
29positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.48193004
30positive regulation of mitotic sister chromatid separation (GO:1901970)3.48193004
31DNA replication checkpoint (GO:0000076)3.46855488
32DNA strand elongation involved in DNA replication (GO:0006271)3.46403314
33DNA replication-dependent nucleosome organization (GO:0034723)3.46254094
34DNA replication-dependent nucleosome assembly (GO:0006335)3.46254094
35double-strand break repair via homologous recombination (GO:0000724)3.43175320
36neural tube formation (GO:0001841)3.42256498
37regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.41600859
38pore complex assembly (GO:0046931)3.40198548
39recombinational repair (GO:0000725)3.39653155
40DNA replication-independent nucleosome assembly (GO:0006336)3.39630084
41DNA replication-independent nucleosome organization (GO:0034724)3.39630084
42postreplication repair (GO:0006301)3.37336192
43centriole replication (GO:0007099)3.35530237
44DNA strand elongation (GO:0022616)3.31618383
45regulation of centrosome cycle (GO:0046605)3.31119127
46positive regulation of histone H3-K4 methylation (GO:0051571)3.28352990
47prenylation (GO:0097354)3.28089723
48protein prenylation (GO:0018342)3.28089723
49positive regulation of granulocyte differentiation (GO:0030854)3.24746902
50regulation of centrosome duplication (GO:0010824)3.24288633
51gene silencing by RNA (GO:0031047)3.24261495
52reciprocal meiotic recombination (GO:0007131)3.24034131
53reciprocal DNA recombination (GO:0035825)3.24034131
54histone exchange (GO:0043486)3.23239994
55sister chromatid segregation (GO:0000819)3.22787446
56protein localization to kinetochore (GO:0034501)3.21758960
57kinetochore assembly (GO:0051382)3.21380275
58microtubule polymerization or depolymerization (GO:0031109)3.20922274
59mitotic recombination (GO:0006312)3.20838508
60regulation of histone H3-K9 methylation (GO:0051570)3.18736623
61mitotic nuclear envelope disassembly (GO:0007077)3.17842902
62male meiosis I (GO:0007141)3.16206451
63regulation of sister chromatid cohesion (GO:0007063)3.13442004
64telomere maintenance via semi-conservative replication (GO:0032201)3.12709491
65DNA deamination (GO:0045006)3.12544978
66DNA methylation involved in gamete generation (GO:0043046)3.11177811
67protein K11-linked deubiquitination (GO:0035871)3.10661229
68histone mRNA catabolic process (GO:0071044)3.08862975
69telomere maintenance via recombination (GO:0000722)3.07438217
70male meiosis (GO:0007140)3.05807091
71somatic hypermutation of immunoglobulin genes (GO:0016446)3.05551699
72somatic diversification of immune receptors via somatic mutation (GO:0002566)3.05551699
73maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.04431292
74histone H3-K9 methylation (GO:0051567)3.04104851
75regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.04086066
76regulation of mitotic spindle checkpoint (GO:1903504)3.04086066
77protein K6-linked ubiquitination (GO:0085020)3.03125532
78establishment of chromosome localization (GO:0051303)3.01326542
79nuclear envelope disassembly (GO:0051081)2.99245202
80membrane disassembly (GO:0030397)2.99245202
81DNA ligation (GO:0006266)2.97588902
82ether lipid metabolic process (GO:0046485)2.93359487
83mitotic G2/M transition checkpoint (GO:0044818)2.93055421
84establishment of protein localization to Golgi (GO:0072600)2.92713878
85nucleotide-excision repair, DNA gap filling (GO:0006297)2.92481815
86regulation of nucleobase-containing compound transport (GO:0032239)2.92325152
87monoubiquitinated protein deubiquitination (GO:0035520)2.91622109
88spindle checkpoint (GO:0031577)2.90987719
89microtubule depolymerization (GO:0007019)2.90805310
90regulation of mitotic metaphase/anaphase transition (GO:0030071)2.89827431
91regulation of spindle organization (GO:0090224)2.89782616
92regulation of chromosome segregation (GO:0051983)2.88024090
93DNA topological change (GO:0006265)2.87654868
94positive regulation of histone methylation (GO:0031062)2.87286299
95* regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.85803411
96translesion synthesis (GO:0019985)2.85627966
97mitotic sister chromatid segregation (GO:0000070)2.85627893
98negative regulation of histone methylation (GO:0031061)2.85187856
99sister chromatid cohesion (GO:0007062)2.85059587
100positive regulation of cell cycle checkpoint (GO:1901978)2.84141391
101regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.83287262
102protein localization to chromosome, centromeric region (GO:0071459)2.82406020
103negative regulation of DNA-dependent DNA replication (GO:2000104)2.80299916
104DNA geometric change (GO:0032392)2.79792146
105DNA duplex unwinding (GO:0032508)2.79718063
106somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.79255275
107somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.79255275
108isotype switching (GO:0045190)2.79255275
109regulation of establishment of cell polarity (GO:2000114)2.78778325
110regulation of helicase activity (GO:0051095)2.78490831
111mismatch repair (GO:0006298)2.78251203
112ATP-dependent chromatin remodeling (GO:0043044)2.78058923
113regulation of sister chromatid segregation (GO:0033045)2.77448570
114regulation of mitotic sister chromatid separation (GO:0010965)2.77448570
115regulation of mitotic sister chromatid segregation (GO:0033047)2.77448570
116intra-S DNA damage checkpoint (GO:0031573)2.77171798
117nucleobase biosynthetic process (GO:0046112)2.76372703
118chromatin assembly or disassembly (GO:0006333)2.76285664
119microtubule anchoring (GO:0034453)2.75519050
120meiosis I (GO:0007127)2.74886509
121purine nucleobase biosynthetic process (GO:0009113)2.74806524
122histone H2A acetylation (GO:0043968)2.74099885
123rRNA catabolic process (GO:0016075)2.72880029
124spindle assembly checkpoint (GO:0071173)2.72525414
125centrosome organization (GO:0051297)2.72371190
126DNA-dependent DNA replication (GO:0006261)2.71794817
127histone H3-K9 modification (GO:0061647)2.71600836
128centrosome duplication (GO:0051298)2.71370235
129mitotic spindle checkpoint (GO:0071174)2.71132517
130chromosome segregation (GO:0007059)2.68264957
131double-strand break repair (GO:0006302)2.68174340
132negative regulation of chromosome segregation (GO:0051985)2.67402581
133myelination (GO:0042552)2.66380664
134meiotic cell cycle (GO:0051321)2.65874531
135negative regulation of mitotic sister chromatid separation (GO:2000816)2.65711655
136negative regulation of mitotic sister chromatid segregation (GO:0033048)2.65711655
137negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.65711655
138negative regulation of sister chromatid segregation (GO:0033046)2.65711655
139resolution of meiotic recombination intermediates (GO:0000712)2.65131173
140viral mRNA export from host cell nucleus (GO:0046784)2.65006729
141N-terminal protein amino acid acetylation (GO:0006474)2.64709973
142ensheathment of neurons (GO:0007272)2.64337511
143axon ensheathment (GO:0008366)2.64337511
144regulation of exit from mitosis (GO:0007096)2.64213661
145protein targeting to Golgi (GO:0000042)2.63601312
146DNA synthesis involved in DNA repair (GO:0000731)2.63575664
147negative T cell selection (GO:0043383)2.61338770
148retinal cone cell development (GO:0046549)2.61138011
149negative regulation of translation, ncRNA-mediated (GO:0040033)2.61000472
150regulation of translation, ncRNA-mediated (GO:0045974)2.61000472
151negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.61000472
152chromosome organization involved in meiosis (GO:0070192)2.58722808
153somatic diversification of immune receptors (GO:0002200)2.58354443
154negative regulation of DNA recombination (GO:0045910)2.56599818
155somatic diversification of immune receptors via germline recombination within a single locus (GO:0002.56369123
156somatic cell DNA recombination (GO:0016444)2.56369123
157response to pheromone (GO:0019236)2.56103843
158DNA recombination (GO:0006310)2.55973727
159histone mRNA metabolic process (GO:0008334)2.55495238
160double-strand break repair via nonhomologous end joining (GO:0006303)2.55344989
161non-recombinational repair (GO:0000726)2.55344989
162somatic diversification of immunoglobulins (GO:0016445)2.55166415
163oocyte development (GO:0048599)2.55149299
164meiotic nuclear division (GO:0007126)2.53424800
165somatic recombination of immunoglobulin gene segments (GO:0016447)2.51902082
166regulation of B cell receptor signaling pathway (GO:0050855)2.50620971
167meiotic cell cycle process (GO:1903046)2.50421046
168interkinetic nuclear migration (GO:0022027)2.49172810

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.41885849
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.39633306
3HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.92992129
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.66282546
5SALL1_21062744_ChIP-ChIP_HESCs_Human3.09589929
6* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.06905200
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.01816262
8ZNF274_21170338_ChIP-Seq_K562_Hela2.63062093
9AR_21909140_ChIP-Seq_LNCAP_Human2.56407121
10RBPJ_22232070_ChIP-Seq_NCS_Mouse2.48376192
11MYC_18555785_ChIP-Seq_MESCs_Mouse2.39604738
12CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.35794756
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.32700484
14KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.28328811
15E2F1_21310950_ChIP-Seq_MCF-7_Human2.22184247
16VDR_22108803_ChIP-Seq_LS180_Human2.17567604
17GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.16880039
18MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.16795417
19NOTCH1_21737748_ChIP-Seq_TLL_Human2.10660375
20MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.10363920
21E2F7_22180533_ChIP-Seq_HELA_Human10.9603313
22ZFP57_27257070_Chip-Seq_ESCs_Mouse1.97928868
23TAF15_26573619_Chip-Seq_HEK293_Human1.96801909
24* EST1_17652178_ChIP-ChIP_JURKAT_Human1.90895608
25* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.90070064
26NELFA_20434984_ChIP-Seq_ESCs_Mouse1.88257736
27YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.87799964
28GBX2_23144817_ChIP-Seq_PC3_Human1.85822021
29* CREB1_15753290_ChIP-ChIP_HEK293T_Human1.83681347
30IGF1R_20145208_ChIP-Seq_DFB_Human1.78176359
31ELK1_19687146_ChIP-ChIP_HELA_Human1.77818515
32TP63_19390658_ChIP-ChIP_HaCaT_Human1.77424015
33SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.76567110
34FUS_26573619_Chip-Seq_HEK293_Human1.76326482
35P300_19829295_ChIP-Seq_ESCs_Human1.76251911
36* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.71156084
37PCGF2_27294783_Chip-Seq_ESCs_Mouse1.70952028
38AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.70157366
39POU5F1_16153702_ChIP-ChIP_HESCs_Human1.69752968
40E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.66680305
41* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.65263776
42EWS_26573619_Chip-Seq_HEK293_Human1.64434057
43VDR_23849224_ChIP-Seq_CD4+_Human1.63487269
44STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.61468962
45CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.59263420
46SOX2_18555785_ChIP-Seq_MESCs_Mouse1.58539236
47MYC_19079543_ChIP-ChIP_MESCs_Mouse1.58014613
48* GABP_17652178_ChIP-ChIP_JURKAT_Human1.56379925
49ER_23166858_ChIP-Seq_MCF-7_Human1.52821290
50EZH2_27294783_Chip-Seq_NPCs_Mouse1.49768015
51SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.47748435
52PADI4_21655091_ChIP-ChIP_MCF-7_Human1.47276277
53MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.45490259
54EGR1_19374776_ChIP-ChIP_THP-1_Human1.43155719
55FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.42747446
56TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.42354539
57BCAT_22108803_ChIP-Seq_LS180_Human1.42281319
58PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.41518313
59UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.41414909
60STAT3_23295773_ChIP-Seq_U87_Human1.40379722
61PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.40257730
62CTBP2_25329375_ChIP-Seq_LNCAP_Human1.38138399
63SOX2_16153702_ChIP-ChIP_HESCs_Human1.38038497
64SUZ12_27294783_Chip-Seq_NPCs_Mouse1.37742848
65IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.36710317
66CBP_20019798_ChIP-Seq_JUKART_Human1.36710317
67HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.36217075
68FOXP3_21729870_ChIP-Seq_TREG_Human1.35496719
69ETS1_20019798_ChIP-Seq_JURKAT_Human1.35227600
70IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.33865903
71HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.33214422
72NFE2_27457419_Chip-Seq_LIVER_Mouse1.31407836
73TCF4_23295773_ChIP-Seq_U87_Human1.30364144
74HOXB4_20404135_ChIP-ChIP_EML_Mouse1.30266468
75FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.28169409
76THAP11_20581084_ChIP-Seq_MESCs_Mouse1.28151799
77PCGF2_27294783_Chip-Seq_NPCs_Mouse1.27651088
78CTBP1_25329375_ChIP-Seq_LNCAP_Human1.27501448
79CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.27401679
80SMAD4_21799915_ChIP-Seq_A2780_Human1.26393812
81MYC_18358816_ChIP-ChIP_MESCs_Mouse1.25721791
82* XRN2_22483619_ChIP-Seq_HELA_Human1.25399602
83IRF8_22096565_ChIP-ChIP_GC-B_Human1.23110475
84HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.22158110
85POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.21654117
86TP53_22573176_ChIP-Seq_HFKS_Human1.21016228
87TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.20705806
88POU3F2_20337985_ChIP-ChIP_501MEL_Human1.20649751
89* KDM5A_27292631_Chip-Seq_BREAST_Human1.17489069
90TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16909022
91POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.16909022
92RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.16188228
93RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.15512968
94AR_25329375_ChIP-Seq_VCAP_Human1.15026157
95CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.14876602
96JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.14690251
97NANOG_18555785_Chip-Seq_ESCs_Mouse1.12850837
98GATA3_26560356_Chip-Seq_TH2_Human1.11206954
99EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.11177279
100TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.10553863
101SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.10158132
102* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.10040031
103FOXA1_21572438_ChIP-Seq_LNCaP_Human1.09005719
104CDX2_22108803_ChIP-Seq_LS180_Human1.08905940
105CRX_20693478_ChIP-Seq_RETINA_Mouse1.08324600
106E2F1_18555785_Chip-Seq_ESCs_Mouse1.08028220
107PRDM14_20953172_ChIP-Seq_ESCs_Human1.07936668
108TTF2_22483619_ChIP-Seq_HELA_Human1.07848686
109* MYB_26560356_Chip-Seq_TH2_Human1.07527367
110FLI1_21867929_ChIP-Seq_TH2_Mouse1.07074434
111IRF1_19129219_ChIP-ChIP_H3396_Human1.06483685
112GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.06377174
113E2F1_18555785_ChIP-Seq_MESCs_Mouse1.06312994
114TCF4_22108803_ChIP-Seq_LS180_Human1.06000445
115KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.05299718
116KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.05299718
117KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.05299718
118EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.05175828
119MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.05162970
120POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.05013206
121ZFX_18555785_ChIP-Seq_MESCs_Mouse1.05008655
122OCT4_21477851_ChIP-Seq_ESCs_Mouse1.04690066
123DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.03160578
124P53_22387025_ChIP-Seq_ESCs_Mouse1.02998435
125PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.01363778
126MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.00765587
127RUNX_20019798_ChIP-Seq_JUKART_Human1.00551599
128SOX2_19829295_ChIP-Seq_ESCs_Human1.00130413
129NANOG_19829295_ChIP-Seq_ESCs_Human1.00130413
130SUZ12_18555785_Chip-Seq_ESCs_Mouse0.99134060
131WT1_19549856_ChIP-ChIP_CCG9911_Human0.98884367
132TOP2B_26459242_ChIP-Seq_MCF-7_Human0.98784612
133DCP1A_22483619_ChIP-Seq_HELA_Human0.98368374
134RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.98184691
135PIAS1_25552417_ChIP-Seq_VCAP_Human0.97531968
136SMAD3_21741376_ChIP-Seq_EPCs_Human0.97523999
137CMYC_18555785_Chip-Seq_ESCs_Mouse0.96363561
138BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.96257427
139ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.96251745
140SOX17_20123909_ChIP-Seq_XEN_Mouse0.92662723
141GABP_19822575_ChIP-Seq_HepG2_Human0.92169370
142CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.91872332
143TFEB_21752829_ChIP-Seq_HELA_Human0.90849740
144* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.90033235
145ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.88592877
146MYC_18940864_ChIP-ChIP_HL60_Human0.88043317
147ELF1_17652178_ChIP-ChIP_JURKAT_Human0.88032780
148SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.87781809
149NANOG_16153702_ChIP-ChIP_HESCs_Human0.86467695
150KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.85759939
151ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.85694893
152POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.85492754
153SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.85443175
154OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.84764089
155CIITA_25753668_ChIP-Seq_RAJI_Human0.84695480
156CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.84245856
157TCF3_18692474_ChIP-Seq_MESCs_Mouse0.82886429
158CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.81692807
159NANOG_18555785_ChIP-Seq_MESCs_Mouse0.80561359
160NANOG_21062744_ChIP-ChIP_HESCs_Human0.75865735
161SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.74680998
162PKCTHETA_26484144_Chip-Seq_BREAST_Human0.74261426
163FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.73070149
164GATA1_26923725_Chip-Seq_HPCs_Mouse0.72455244
165SOX9_26525672_Chip-Seq_HEART_Mouse0.72318033
166EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.71992142
167NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.69990139

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.36759008
2MP0010094_abnormal_chromosome_stability3.60516844
3MP0008877_abnormal_DNA_methylation3.40850798
4MP0004957_abnormal_blastocyst_morpholog2.80487509
5MP0003121_genomic_imprinting2.78769610
6MP0003111_abnormal_nucleus_morphology2.77344131
7MP0003077_abnormal_cell_cycle2.73613176
8MP0000372_irregular_coat_pigmentation2.53658913
9MP0008058_abnormal_DNA_repair2.45535217
10MP0003787_abnormal_imprinting2.28715181
11MP0003718_maternal_effect2.28547342
12MP0005075_abnormal_melanosome_morpholog2.24319986
13MP0003123_paternal_imprinting2.19231121
14MP0003937_abnormal_limbs/digits/tail_de2.10651832
15MP0008932_abnormal_embryonic_tissue2.10213837
16MP0003763_abnormal_thymus_physiology2.03815384
17MP0006072_abnormal_retinal_apoptosis2.02164583
18MP0008007_abnormal_cellular_replicative2.02069877
19MP0001293_anophthalmia1.96411845
20MP0003693_abnormal_embryo_hatching1.95046766
21MP0003950_abnormal_plasma_membrane1.92815320
22MP0000566_synostosis1.87445405
23MP0005645_abnormal_hypothalamus_physiol1.81574765
24MP0005171_absent_coat_pigmentation1.72633850
25MP0001730_embryonic_growth_arrest1.68078937
26MP0000015_abnormal_ear_pigmentation1.64206460
27MP0005671_abnormal_response_to1.62723836
28MP0000350_abnormal_cell_proliferation1.61939072
29MP0002938_white_spotting1.58397324
30MP0005174_abnormal_tail_pigmentation1.57598944
31MP0000920_abnormal_myelination1.56500174
32MP0010307_abnormal_tumor_latency1.55397513
33MP0005253_abnormal_eye_physiology1.55125999
34MP0010030_abnormal_orbit_morphology1.54167263
35MP0006292_abnormal_olfactory_placode1.49479124
36MP0002085_abnormal_embryonic_tissue1.49195471
37MP0002084_abnormal_developmental_patter1.48658717
38MP0010678_abnormal_skin_adnexa1.46896589
39MP0000383_abnormal_hair_follicle1.45122906
40MP0002210_abnormal_sex_determination1.43662847
41MP0001672_abnormal_embryogenesis/_devel1.42983005
42MP0005380_embryogenesis_phenotype1.42983005
43MP0004197_abnormal_fetal_growth/weight/1.40435678
44MP0004134_abnormal_chest_morphology1.39386029
45MP0001697_abnormal_embryo_size1.39122092
46MP0003122_maternal_imprinting1.38599583
47MP0001835_abnormal_antigen_presentation1.37879576
48MP0000428_abnormal_craniofacial_morphol1.37395956
49MP0002396_abnormal_hematopoietic_system1.36487636
50MP0003890_abnormal_embryonic-extraembry1.36439062
51MP0003195_calcinosis1.33126777
52MP0000537_abnormal_urethra_morphology1.31588619
53MP0003984_embryonic_growth_retardation1.29683801
54MP0003315_abnormal_perineum_morphology1.29198970
55MP0005551_abnormal_eye_electrophysiolog1.27201900
56MP0000703_abnormal_thymus_morphology1.27089123
57MP0008995_early_reproductive_senescence1.26444010
58MP0005623_abnormal_meninges_morphology1.24450623
59MP0002088_abnormal_embryonic_growth/wei1.23201927
60MP0003786_premature_aging1.20166414
61MP0001800_abnormal_humoral_immune1.19759387
62MP0003136_yellow_coat_color1.19626321
63MP0003755_abnormal_palate_morphology1.19098379
64MP0001145_abnormal_male_reproductive1.18557893
65MP0010352_gastrointestinal_tract_polyps1.18333091
66MP0001929_abnormal_gametogenesis1.18139515
67MP0000689_abnormal_spleen_morphology1.17108049
68MP0002398_abnormal_bone_marrow1.16985589
69MP0001485_abnormal_pinna_reflex1.16442557
70MP0002928_abnormal_bile_duct1.14825672
71MP0009250_abnormal_appendicular_skeleto1.13377361
72MP0002092_abnormal_eye_morphology1.12075421
73MP0002138_abnormal_hepatobiliary_system1.11957692
74MP0000432_abnormal_head_morphology1.11278675
75MP0009053_abnormal_anal_canal1.11097849
76MP0001986_abnormal_taste_sensitivity1.11080014
77MP0002086_abnormal_extraembryonic_tissu1.10181258
78MP0005389_reproductive_system_phenotype1.07730731
79MP0002080_prenatal_lethality1.07542389
80MP0009703_decreased_birth_body1.05840519
81MP0000653_abnormal_sex_gland1.03430455
82MP0001286_abnormal_eye_development1.03249927
83MP0003861_abnormal_nervous_system1.02837082
84MP0005367_renal/urinary_system_phenotyp1.02134744
85MP0000516_abnormal_urinary_system1.02134744
86MP0001119_abnormal_female_reproductive1.01252026
87MP0003938_abnormal_ear_development1.00544489
88MP0005408_hypopigmentation1.00058797
89MP0000569_abnormal_digit_pigmentation0.97646628
90MP0000462_abnormal_digestive_system0.96433750
91MP0003935_abnormal_craniofacial_develop0.96402171
92MP0003943_abnormal_hepatobiliary_system0.96283727
93MP0002019_abnormal_tumor_incidence0.95696321
94MP0002102_abnormal_ear_morphology0.95492965
95MP0002006_tumorigenesis0.95333126
96MP0005395_other_phenotype0.94865059
97MP0000427_abnormal_hair_cycle0.94484394
98MP0004381_abnormal_hair_follicle0.94141927
99MP0000647_abnormal_sebaceous_gland0.93852008
100MP0003385_abnormal_body_wall0.92339926
101MP0004142_abnormal_muscle_tone0.91885665
102MP0002722_abnormal_immune_system0.91721354
103MP0002166_altered_tumor_susceptibility0.91289981
104MP0002114_abnormal_axial_skeleton0.89882347
105MP0004147_increased_porphyrin_level0.89722303
106MP0002111_abnormal_tail_morphology0.89661586
107MP0001324_abnormal_eye_pigmentation0.89610245
108MP0005409_darkened_coat_color0.89334514
109MP0000778_abnormal_nervous_system0.89175489
110MP0001919_abnormal_reproductive_system0.88524212
111MP0002638_abnormal_pupillary_reflex0.87789188
112MP0002277_abnormal_respiratory_mucosa0.87557617
113MP0008961_abnormal_basal_metabolism0.87203503
114MP0001529_abnormal_vocalization0.86380410
115MP0003698_abnormal_male_reproductive0.85551001
116MP0001346_abnormal_lacrimal_gland0.84665189
117MP0004885_abnormal_endolymph0.84359229
118MP0000716_abnormal_immune_system0.84154577
119MP0002420_abnormal_adaptive_immunity0.84019099
120MP0002233_abnormal_nose_morphology0.83810226
121MP0002009_preneoplasia0.83606359
122MP0003942_abnormal_urinary_system0.83590506
123MP0004808_abnormal_hematopoietic_stem0.83379897
124MP0003119_abnormal_digestive_system0.82814368
125MP0000313_abnormal_cell_death0.82653852
126MP0001819_abnormal_immune_cell0.82385554
127MP0000733_abnormal_muscle_development0.81482894
128MP0002095_abnormal_skin_pigmentation0.80617858
129MP0003115_abnormal_respiratory_system0.79968332
130MP0008789_abnormal_olfactory_epithelium0.79819196
131MP0001299_abnormal_eye_distance/0.79494440
132MP0002116_abnormal_craniofacial_bone0.79354410
133MP0002177_abnormal_outer_ear0.79288725
134MP0008872_abnormal_physiological_respon0.79263904
135MP0005076_abnormal_cell_differentiation0.78956292
136MP0003699_abnormal_female_reproductive0.78633841
137MP0005647_abnormal_sex_gland0.78575490
138MP0005391_vision/eye_phenotype0.78266592
139MP0009697_abnormal_copulation0.78008957
140MP0004133_heterotaxia0.77991749
141MP0000631_abnormal_neuroendocrine_gland0.77204208
142MP0000371_diluted_coat_color0.76924219
143MP0005310_abnormal_salivary_gland0.76548677
144MP0002723_abnormal_immune_serum0.76337529
145MP0002452_abnormal_antigen_presenting0.75391745
146MP0002697_abnormal_eye_size0.75324954
147MP0006035_abnormal_mitochondrial_morpho0.75300597
148MP0002160_abnormal_reproductive_system0.75110178
149MP0001984_abnormal_olfaction0.74199101
150MP0003632_abnormal_nervous_system0.73471151
151MP0005646_abnormal_pituitary_gland0.71661624
152MP0002751_abnormal_autonomic_nervous0.71563336
153MP0002429_abnormal_blood_cell0.67973072
154MP0005266_abnormal_metabolism0.66632612
155MP0004215_abnormal_myocardial_fiber0.66356802

Predicted human phenotypes

RankGene SetZ-score
1Volvulus (HP:0002580)3.66646094
2Pancreatic fibrosis (HP:0100732)3.56651732
3Pancreatic cysts (HP:0001737)3.35879538
4Birth length less than 3rd percentile (HP:0003561)3.27502208
5Chromsome breakage (HP:0040012)3.21882031
6Abnormality of the labia minora (HP:0012880)3.19952797
7Abnormality of the renal cortex (HP:0011035)3.07032726
8Ectopic kidney (HP:0000086)3.04991189
9Renal cortical cysts (HP:0000803)2.98083583
10Chromosomal breakage induced by crosslinking agents (HP:0003221)2.92922102
11Chronic hepatic failure (HP:0100626)2.90825654
12True hermaphroditism (HP:0010459)2.85976443
13Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.85866238
14Degeneration of the lateral corticospinal tracts (HP:0002314)2.85866238
15Molar tooth sign on MRI (HP:0002419)2.84962958
16Abnormality of midbrain morphology (HP:0002418)2.84962958
17Thyroiditis (HP:0100646)2.80980670
18T lymphocytopenia (HP:0005403)2.80936088
19Supernumerary spleens (HP:0009799)2.77451918
20Aplasia/Hypoplasia of the tibia (HP:0005772)2.68574455
21Abnormality of T cell number (HP:0011839)2.67206523
22Abnormality of chromosome stability (HP:0003220)2.64362278
23Medulloblastoma (HP:0002885)2.60488609
24Cerebral hypomyelination (HP:0006808)2.59831206
25Severe combined immunodeficiency (HP:0004430)2.57943363
26Embryonal renal neoplasm (HP:0011794)2.57316238
27Nephroblastoma (Wilms tumor) (HP:0002667)2.56478408
28Impulsivity (HP:0100710)2.50953718
29Abnormal biliary tract physiology (HP:0012439)2.48695487
30Bile duct proliferation (HP:0001408)2.48695487
31Facial hemangioma (HP:0000329)2.46320151
32Fair hair (HP:0002286)2.42902533
33Short tibia (HP:0005736)2.40930611
34Nephronophthisis (HP:0000090)2.40419255
35Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.40034584
36Short 4th metacarpal (HP:0010044)2.40034584
37Neoplasm of the oral cavity (HP:0100649)2.38056494
38Duplicated collecting system (HP:0000081)2.37181295
39Cupped ear (HP:0000378)2.35520048
40Absent radius (HP:0003974)2.35140764
41Patellar aplasia (HP:0006443)2.33529005
42Clubbing of toes (HP:0100760)2.31743506
43Abnormal lung lobation (HP:0002101)2.29801010
44Oligodactyly (hands) (HP:0001180)2.26863704
45Aplasia/Hypoplasia of the tongue (HP:0010295)2.26451546
46Abnormality of B cell number (HP:0010975)2.25796798
47Abnormality of the renal medulla (HP:0100957)2.25793862
48Abnormality of the renal collecting system (HP:0004742)2.25186541
49Esophageal atresia (HP:0002032)2.25149837
50Gaze-evoked nystagmus (HP:0000640)2.24802697
51Medial flaring of the eyebrow (HP:0010747)2.19962555
52Panhypogammaglobulinemia (HP:0003139)2.19732630
53Breast hypoplasia (HP:0003187)2.18605212
54Combined immunodeficiency (HP:0005387)2.17541576
55Absent forearm bone (HP:0003953)2.17386493
56Aplasia involving forearm bones (HP:0009822)2.17386493
57Aplasia/Hypoplasia of the patella (HP:0006498)2.16508395
58Increased nuchal translucency (HP:0010880)2.14745847
59Abnormal hair whorl (HP:0010721)2.14191894
60Abnormality of the fingertips (HP:0001211)2.13311625
61Meckel diverticulum (HP:0002245)2.13163023
62Abnormality of the ileum (HP:0001549)2.09679312
63Stenosis of the external auditory canal (HP:0000402)2.09345579
64Atresia of the external auditory canal (HP:0000413)2.08077629
65Congenital stationary night blindness (HP:0007642)2.07416532
66Coronal craniosynostosis (HP:0004440)2.07134286
67Stomach cancer (HP:0012126)2.06870976
68Tubulointerstitial nephritis (HP:0001970)2.04483173
69Neoplasm of the adrenal cortex (HP:0100641)2.03687295
70Median cleft lip (HP:0000161)2.02417311
71Trigonocephaly (HP:0000243)2.01792034
72Abnormal auditory evoked potentials (HP:0006958)1.99321955
73Duodenal stenosis (HP:0100867)1.98026582
74Small intestinal stenosis (HP:0012848)1.98026582
75IgG deficiency (HP:0004315)1.97537705
76Postaxial foot polydactyly (HP:0001830)1.97227054
77Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.96905364
78Abnormality of alanine metabolism (HP:0010916)1.96905364
79Hyperalaninemia (HP:0003348)1.96905364
80Microtia (HP:0008551)1.96145455
81Proximal placement of thumb (HP:0009623)1.95998197
82Abnormality of the phalanges of the hallux (HP:0010057)1.95159623
83Adrenal hypoplasia (HP:0000835)1.95096309
84Generalized hypopigmentation of hair (HP:0011358)1.94689298
85Gastrointestinal atresia (HP:0002589)1.94650373
86Progressive inability to walk (HP:0002505)1.93893992
87B lymphocytopenia (HP:0010976)1.92984462
88Deviation of the thumb (HP:0009603)1.92134659
89Sloping forehead (HP:0000340)1.91470827
90Aplasia/Hypoplasia of the uvula (HP:0010293)1.91244917
91Decreased lacrimation (HP:0000633)1.91083572
92Anteriorly placed anus (HP:0001545)1.90947688
93Pancreatic islet-cell hyperplasia (HP:0004510)1.89328271
94Prominent occiput (HP:0000269)1.89235296
95Abnormality of the parietal bone (HP:0002696)1.88060588
96Alacrima (HP:0000522)1.87717736
97Abnormality of T cells (HP:0002843)1.86923591
98Abnormality of incisor morphology (HP:0011063)1.86821580
99Abnormality of chromosome segregation (HP:0002916)1.86178016
100Aplasia/Hypoplasia of the sternum (HP:0006714)1.85864472
101Dyschromatopsia (HP:0007641)1.85764439
102Ependymoma (HP:0002888)1.85610432
103Aplasia/Hypoplasia of the fovea (HP:0008060)1.85102854
104Hypoplasia of the fovea (HP:0007750)1.85102854
105Stomatitis (HP:0010280)1.84679399
106Cystic liver disease (HP:0006706)1.84644603
107Long eyelashes (HP:0000527)1.84543782
108Abolished electroretinogram (ERG) (HP:0000550)1.83938664
109Rib fusion (HP:0000902)1.83418545
110Clitoromegaly (HP:0000057)1.83400100
111Preaxial hand polydactyly (HP:0001177)1.81573354
112Relative macrocephaly (HP:0004482)1.81384247
113Abnormality of the prostate (HP:0008775)1.80846123
114Prostate neoplasm (HP:0100787)1.80048157
115Abnormality of the corticospinal tract (HP:0002492)1.79998120
116Autoimmune hemolytic anemia (HP:0001890)1.79141626
117Acute myeloid leukemia (HP:0004808)1.78900599
118Colon cancer (HP:0003003)1.78720960
119Abnormality of the distal phalanx of the thumb (HP:0009617)1.78667708
120Glioma (HP:0009733)1.78483893
121Abnormality of the septum pellucidum (HP:0007375)1.78173220
122Abnormality of the incisor (HP:0000676)1.78115471
123Abnormality of the preputium (HP:0100587)1.77724659
124Abnormality of the fovea (HP:0000493)1.77720945
125Congenital hepatic fibrosis (HP:0002612)1.77418258
126Hypoplasia of the thymus (HP:0000778)1.76770775
127Anencephaly (HP:0002323)1.76057431
128Absent septum pellucidum (HP:0001331)1.75801450
129Central scotoma (HP:0000603)1.74990604
130Papillary thyroid carcinoma (HP:0002895)1.74623875
131Broad thumb (HP:0011304)1.73382904
132Duplication of thumb phalanx (HP:0009942)1.72259906
133Abnormality of the astrocytes (HP:0100707)1.71696668
134Astrocytoma (HP:0009592)1.71696668
135Morphological abnormality of the inner ear (HP:0011390)1.71550826
136Small hand (HP:0200055)1.71025175
137Supernumerary bones of the axial skeleton (HP:0009144)1.70612718
138Abnormality of eosinophils (HP:0001879)1.69995618
139Absent rod-and cone-mediated responses on ERG (HP:0007688)1.69297548
140Abnormality of the duodenum (HP:0002246)1.68701415
141Abnormal number of incisors (HP:0011064)1.67854618
142Microglossia (HP:0000171)1.67219355
143Sparse lateral eyebrow (HP:0005338)1.67143166
144Myelodysplasia (HP:0002863)1.66953064
145Attenuation of retinal blood vessels (HP:0007843)1.66884489
146Oligodactyly (HP:0012165)1.66813359
147Low anterior hairline (HP:0000294)1.65933906
148Thyroid-stimulating hormone excess (HP:0002925)1.65918102
149Rhabdomyosarcoma (HP:0002859)1.65612905
150Sensory axonal neuropathy (HP:0003390)1.65410534
151Abnormal delayed hypersensitivity skin test (HP:0002963)1.64990545
152Abnormal rod and cone electroretinograms (HP:0008323)1.64828196
153Hypoplastic pelvis (HP:0008839)1.64416717
154Type II lissencephaly (HP:0007260)1.63540285
155Thyroid carcinoma (HP:0002890)1.63216017
156Agnosia (HP:0010524)1.62576696
157Cafe-au-lait spot (HP:0000957)1.61037231
158Capillary hemangiomas (HP:0005306)1.60405711
159Aqueductal stenosis (HP:0002410)1.60280876
160CNS hypomyelination (HP:0003429)1.59773741
161Intestinal atresia (HP:0011100)1.59436592
162Aplasia/Hypoplasia of the earlobes (HP:0009906)1.58287663
163Supernumerary ribs (HP:0005815)1.58195495
164Abnormality of the columella (HP:0009929)1.58143169
165Premature graying of hair (HP:0002216)1.57796770
166Metaphyseal dysplasia (HP:0100255)1.56453937
167Broad phalanges of the hand (HP:0009768)1.55666490
168Bone marrow hypocellularity (HP:0005528)1.54680801

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.60722230
2STK392.74882832
3CDK122.62058627
4BRD42.53570785
5BUB12.51545407
6WEE12.41861233
7TAOK32.37819625
8MKNK12.33435545
9FGFR22.24239423
10PLK42.19936787
11SRPK12.14449660
12LATS12.03464338
13VRK12.00683005
14TEC1.96741705
15TXK1.95068556
16BRSK21.87661681
17TTK1.87573701
18MKNK21.87429322
19PLK31.86983683
20NEK21.85805511
21PNCK1.71550111
22NUAK11.69497465
23PLK21.68929263
24WNK31.68363252
25TSSK61.66729639
26OXSR11.65267753
27CHEK21.61890903
28ZAK1.60439924
29PASK1.51442468
30BCR1.50683518
31ATR1.48974483
32CHEK11.43811386
33TRIM281.41928186
34AKT31.41593525
35TLK11.40314573
36PLK11.39971179
37TNIK1.38250868
38ADRBK21.38221960
39CSNK1A1L1.37223239
40MAP3K41.35583255
41NLK1.32307667
42MAP4K21.31196379
43MELK1.29283529
44TGFBR11.29237343
45CLK11.28434172
46AURKB1.25470647
47STK31.24370841
48GRK11.21939982
49WNK11.21009680
50ATM1.20029833
51ERBB31.19900919
52MET1.18314640
53RPS6KA51.17480453
54NEK61.17188480
55STK41.16104767
56CSNK1G31.14467789
57INSRR1.11254293
58TRPM71.10689157
59EIF2AK11.09232447
60EPHB11.08394543
61ACVR1B1.07499795
62SGK4941.04710553
63SGK2231.04710553
64PKN11.03498733
65STK101.02683990
66CSNK1G11.01393850
67DYRK31.00559235
68FRK0.97996999
69CDK70.97841702
70ITK0.96875885
71CDK10.95094394
72* CDK20.94032245
73BRSK10.91090686
74TYRO30.89408730
75MST40.84294013
76BTK0.84076086
77PIM10.82142015
78CSNK1D0.79030294
79RPS6KB20.77066404
80CDK190.77008704
81SYK0.76976405
82MAPKAPK50.75616010
83MAP4K10.74969242
84MARK30.74551496
85UHMK10.73615475
86CDK30.69174109
87MAP3K80.68875171
88IKBKE0.68638942
89PAK30.67666514
90SGK20.67032642
91CAMK1G0.66721288
92EPHA20.65774867
93CSNK1G20.65478406
94CDK40.65004734
95CAMKK20.64678708
96IRAK10.64276638
97TESK20.64106889
98YES10.63641019
99EIF2AK30.63378181
100PRKCQ0.62838323
101AURKA0.62735085
102PTK2B0.59760194
103BMPR1B0.59288184
104IRAK40.59075503
105CDK60.57695908
106FGFR10.55885528
107PBK0.55852791
108CSNK1E0.55251790
109CDK90.54504799
110FLT30.54430283
111ALK0.53998501
112LYN0.53969612
113PIK3CG0.52908880
114ROCK20.52327700
115MAPK140.52102496
116PRKDC0.52099786
117GSK3B0.50993668
118PDGFRB0.49785087
119RAF10.49742260
120LCK0.49011956
121CSNK2A20.48543426
122MAP3K140.48337758
123EIF2AK20.47851346
124CCNB10.47406632
125KIT0.46646170
126WNK40.46547959
127STK38L0.46510227
128FES0.46255493
129RPS6KA40.44222671
130PAK10.44057952
131PRKCE0.44030120
132STK240.44022340
133PINK10.43361301
134MAPK100.43241024
135MAPK130.42195873
136BMPR20.42152796
137CASK0.40883169
138MTOR0.40350220
139MAPK10.40033848
140HCK0.39220363
141EGFR0.39195420
142FGFR30.38703184
143DYRK20.38126235
144IKBKB0.37971916
145CAMK2B0.35633143
146LIMK10.35620889
147SGK30.34179608
148PAK20.33394494

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.91348260
2Mismatch repair_Homo sapiens_hsa034303.67747439
3Cell cycle_Homo sapiens_hsa041103.05507040
4Non-homologous end-joining_Homo sapiens_hsa034502.93335151
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.88910672
6Spliceosome_Homo sapiens_hsa030402.74371098
7Homologous recombination_Homo sapiens_hsa034402.69439666
8Nucleotide excision repair_Homo sapiens_hsa034202.67499021
9RNA transport_Homo sapiens_hsa030132.64983100
10Basal transcription factors_Homo sapiens_hsa030222.55624386
11RNA polymerase_Homo sapiens_hsa030202.52605506
12Fanconi anemia pathway_Homo sapiens_hsa034602.51585239
13Base excision repair_Homo sapiens_hsa034102.37687756
14RNA degradation_Homo sapiens_hsa030182.22623747
15mRNA surveillance pathway_Homo sapiens_hsa030152.14664683
16Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.93251248
17Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.87744199
18One carbon pool by folate_Homo sapiens_hsa006701.82232022
19Systemic lupus erythematosus_Homo sapiens_hsa053221.72339852
20Vitamin B6 metabolism_Homo sapiens_hsa007501.59076827
21Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.56591632
22Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.56096853
23p53 signaling pathway_Homo sapiens_hsa041151.46386383
24Steroid biosynthesis_Homo sapiens_hsa001001.43667007
25Pyrimidine metabolism_Homo sapiens_hsa002401.39991973
26Regulation of autophagy_Homo sapiens_hsa041401.37568843
27Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.37217382
28Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.32363912
29Caffeine metabolism_Homo sapiens_hsa002321.30883228
30Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.28494128
31MicroRNAs in cancer_Homo sapiens_hsa052061.25165068
32Intestinal immune network for IgA production_Homo sapiens_hsa046721.24989372
33Viral carcinogenesis_Homo sapiens_hsa052031.22396268
34Type I diabetes mellitus_Homo sapiens_hsa049401.21081705
35Ether lipid metabolism_Homo sapiens_hsa005651.20755342
36Alcoholism_Homo sapiens_hsa050341.19553539
37Maturity onset diabetes of the young_Homo sapiens_hsa049501.19104792
38Allograft rejection_Homo sapiens_hsa053301.19103065
39Selenocompound metabolism_Homo sapiens_hsa004501.18891199
40Graft-versus-host disease_Homo sapiens_hsa053321.18773175
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.17842836
42Protein export_Homo sapiens_hsa030601.17327738
43Oocyte meiosis_Homo sapiens_hsa041141.15496205
44Olfactory transduction_Homo sapiens_hsa047401.10945858
45Asthma_Homo sapiens_hsa053101.09707976
46Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.09706649
47Propanoate metabolism_Homo sapiens_hsa006401.05041319
48TGF-beta signaling pathway_Homo sapiens_hsa043501.02238536
49Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.02040296
50Hedgehog signaling pathway_Homo sapiens_hsa043401.01576536
51Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.00379516
52Purine metabolism_Homo sapiens_hsa002300.97989138
53Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.97415780
54Prostate cancer_Homo sapiens_hsa052150.95094823
55Nitrogen metabolism_Homo sapiens_hsa009100.94538059
56Epstein-Barr virus infection_Homo sapiens_hsa051690.94323547
57Hippo signaling pathway_Homo sapiens_hsa043900.93576817
58Transcriptional misregulation in cancer_Homo sapiens_hsa052020.92818748
59Hematopoietic cell lineage_Homo sapiens_hsa046400.92239125
60Basal cell carcinoma_Homo sapiens_hsa052170.91289240
61Axon guidance_Homo sapiens_hsa043600.88309521
62Renal cell carcinoma_Homo sapiens_hsa052110.86536783
63Jak-STAT signaling pathway_Homo sapiens_hsa046300.85491256
64Butanoate metabolism_Homo sapiens_hsa006500.84943285
65Proteasome_Homo sapiens_hsa030500.83212168
66Tight junction_Homo sapiens_hsa045300.80828205
67Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.80313397
68Small cell lung cancer_Homo sapiens_hsa052220.77659660
69HTLV-I infection_Homo sapiens_hsa051660.75331717
70Wnt signaling pathway_Homo sapiens_hsa043100.74116115
71Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.73569602
72Peroxisome_Homo sapiens_hsa041460.73367699
73Fatty acid elongation_Homo sapiens_hsa000620.70730382
74Notch signaling pathway_Homo sapiens_hsa043300.67587241
75Autoimmune thyroid disease_Homo sapiens_hsa053200.67104971
76Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.67012978
77Circadian rhythm_Homo sapiens_hsa047100.66327962
78Herpes simplex infection_Homo sapiens_hsa051680.65147550
79Sphingolipid metabolism_Homo sapiens_hsa006000.61977832
80Pathways in cancer_Homo sapiens_hsa052000.61304894
81RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.60135669
82Colorectal cancer_Homo sapiens_hsa052100.59735702
83Adherens junction_Homo sapiens_hsa045200.59093469
84Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.58420132
85Cysteine and methionine metabolism_Homo sapiens_hsa002700.56099489
86Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.55474187
87ABC transporters_Homo sapiens_hsa020100.55238798
88Pancreatic cancer_Homo sapiens_hsa052120.54488816
89Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.54389223
90PI3K-Akt signaling pathway_Homo sapiens_hsa041510.53560986
91Platelet activation_Homo sapiens_hsa046110.53103013
92Dorso-ventral axis formation_Homo sapiens_hsa043200.52488681
93Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.51687343
94B cell receptor signaling pathway_Homo sapiens_hsa046620.51299642
95Linoleic acid metabolism_Homo sapiens_hsa005910.49876584
96Hepatitis B_Homo sapiens_hsa051610.49155650
97Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.49100062
98Phosphatidylinositol signaling system_Homo sapiens_hsa040700.48876091
99Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.48435712
100ECM-receptor interaction_Homo sapiens_hsa045120.45280366
101Regulation of actin cytoskeleton_Homo sapiens_hsa048100.44624683
102T cell receptor signaling pathway_Homo sapiens_hsa046600.43867579
103Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.43189558
104Melanoma_Homo sapiens_hsa052180.43069540
105Taste transduction_Homo sapiens_hsa047420.42381590
106Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.40892835
107Ribosome_Homo sapiens_hsa030100.40395030
108SNARE interactions in vesicular transport_Homo sapiens_hsa041300.40270457
109Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.39990345
110alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.38400183
111Lysine degradation_Homo sapiens_hsa003100.38242345
112Thyroid cancer_Homo sapiens_hsa052160.37084447
113Chronic myeloid leukemia_Homo sapiens_hsa052200.35870001
114Serotonergic synapse_Homo sapiens_hsa047260.34573056
115Focal adhesion_Homo sapiens_hsa045100.34500739
116Sphingolipid signaling pathway_Homo sapiens_hsa040710.33248814
117Antigen processing and presentation_Homo sapiens_hsa046120.33110647
118Non-small cell lung cancer_Homo sapiens_hsa052230.32315853
119Glycerolipid metabolism_Homo sapiens_hsa005610.32136161
120NOD-like receptor signaling pathway_Homo sapiens_hsa046210.31511994
121NF-kappa B signaling pathway_Homo sapiens_hsa040640.31424843
122ErbB signaling pathway_Homo sapiens_hsa040120.30937331
123Proteoglycans in cancer_Homo sapiens_hsa052050.30203370
124Endometrial cancer_Homo sapiens_hsa052130.30195407
125Leukocyte transendothelial migration_Homo sapiens_hsa046700.29463546
126Ras signaling pathway_Homo sapiens_hsa040140.29236420
127Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.28585695
128Folate biosynthesis_Homo sapiens_hsa007900.28465964
129MAPK signaling pathway_Homo sapiens_hsa040100.28022440
130FoxO signaling pathway_Homo sapiens_hsa040680.27914069
131mTOR signaling pathway_Homo sapiens_hsa041500.27372752
132Ovarian steroidogenesis_Homo sapiens_hsa049130.27326165
133Thyroid hormone signaling pathway_Homo sapiens_hsa049190.26872674
134Phototransduction_Homo sapiens_hsa047440.26762742
135Measles_Homo sapiens_hsa051620.25188406
136Nicotine addiction_Homo sapiens_hsa050330.24673028
137Viral myocarditis_Homo sapiens_hsa054160.23845407
138Primary immunodeficiency_Homo sapiens_hsa053400.23047085
139Shigellosis_Homo sapiens_hsa051310.20374750
140Inositol phosphate metabolism_Homo sapiens_hsa005620.19159306
141N-Glycan biosynthesis_Homo sapiens_hsa005100.18300379
142Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.18071179

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