NOP9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA strand elongation involved in DNA replication (GO:0006271)4.34417830
2DNA unwinding involved in DNA replication (GO:0006268)4.29898754
3folic acid-containing compound biosynthetic process (GO:0009396)4.27270171
4protein localization to kinetochore (GO:0034501)4.20017633
5DNA replication initiation (GO:0006270)4.15205305
6nucleobase biosynthetic process (GO:0046112)4.14280018
7DNA strand elongation (GO:0022616)4.11720028
8DNA replication-dependent nucleosome assembly (GO:0006335)4.04045348
9DNA replication-dependent nucleosome organization (GO:0034723)4.04045348
10protein localization to chromosome, centromeric region (GO:0071459)4.01587272
11mitotic nuclear envelope disassembly (GO:0007077)3.97806273
12focal adhesion assembly (GO:0048041)3.96898511
13cell-substrate adherens junction assembly (GO:0007045)3.96898511
14formation of translation preinitiation complex (GO:0001731)3.95999036
15Golgi transport vesicle coating (GO:0048200)3.93196526
16COPI coating of Golgi vesicle (GO:0048205)3.93196526
17purine nucleobase biosynthetic process (GO:0009113)3.89225893
18maturation of SSU-rRNA (GO:0030490)3.88694206
19telomere maintenance via semi-conservative replication (GO:0032201)3.86055011
20DNA replication checkpoint (GO:0000076)3.84839609
21adherens junction assembly (GO:0034333)3.81692316
22nuclear pore organization (GO:0006999)3.80987614
23folic acid metabolic process (GO:0046655)3.77185306
24DNA deamination (GO:0045006)3.77002013
25membrane disassembly (GO:0030397)3.68670674
26nuclear envelope disassembly (GO:0051081)3.68670674
27nuclear pore complex assembly (GO:0051292)3.62702752
28protein localization to endosome (GO:0036010)3.57422340
29viral transcription (GO:0019083)3.56334565
30embryonic process involved in female pregnancy (GO:0060136)3.55419752
31translational termination (GO:0006415)3.54271404
32mitotic metaphase plate congression (GO:0007080)3.53520104
33cell-substrate junction assembly (GO:0007044)3.52975196
34pinocytosis (GO:0006907)3.52089268
35regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.51380908
36IMP biosynthetic process (GO:0006188)3.45497088
37ribosome biogenesis (GO:0042254)3.44286236
38negative regulation of erythrocyte differentiation (GO:0045647)3.44150589
39ribosome assembly (GO:0042255)3.43048833
40ribosomal small subunit assembly (GO:0000028)3.40871000
41telomere maintenance via recombination (GO:0000722)3.39925161
42mitotic sister chromatid segregation (GO:0000070)3.35672733
43translational initiation (GO:0006413)3.34200569
44ribosomal large subunit biogenesis (GO:0042273)3.31262466
45translational elongation (GO:0006414)3.30418184
46regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.30234918
47ribonucleoprotein complex biogenesis (GO:0022613)3.28672215
48regulation of NFAT protein import into nucleus (GO:0051532)3.27594338
49mitotic recombination (GO:0006312)3.22037435
50mitotic chromosome condensation (GO:0007076)3.19318067
51regulation of spindle organization (GO:0090224)3.19240551
52regulation of histone H3-K27 methylation (GO:0061085)3.19050739
53chromatin remodeling at centromere (GO:0031055)3.17548548
54regulation of RNA export from nucleus (GO:0046831)3.15677333
55mannose metabolic process (GO:0006013)3.14437495
56ribosomal small subunit biogenesis (GO:0042274)3.14386915
57nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.11828330
58IMP metabolic process (GO:0046040)3.10266763
59proline biosynthetic process (GO:0006561)3.09440770
60regulation of glucose import in response to insulin stimulus (GO:2001273)3.08812815
61cytoskeletal anchoring at plasma membrane (GO:0007016)3.08646888
62CENP-A containing nucleosome assembly (GO:0034080)3.08584849
63regulation of nucleobase-containing compound transport (GO:0032239)3.08155897
64rRNA processing (GO:0006364)3.06019535
65regulation of cholesterol homeostasis (GO:2000188)3.05506804
66telomere maintenance via telomere lengthening (GO:0010833)3.05322827
67apoptotic process involved in morphogenesis (GO:0060561)3.02421714
68histone exchange (GO:0043486)3.01680396
69spliceosomal snRNP assembly (GO:0000387)3.01224589
70retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.01216229
71sister chromatid segregation (GO:0000819)3.01051546
72DNA replication-independent nucleosome organization (GO:0034724)3.00873681
73DNA replication-independent nucleosome assembly (GO:0006336)3.00873681
74heterochromatin organization (GO:0070828)3.00682228
75regulation of mammary gland epithelial cell proliferation (GO:0033599)3.00280538
76attachment of spindle microtubules to kinetochore (GO:0008608)2.99840608
77metaphase plate congression (GO:0051310)2.99262367
783-UTR-mediated mRNA stabilization (GO:0070935)2.98968604
79glycine metabolic process (GO:0006544)2.98426594
80cellular response to epidermal growth factor stimulus (GO:0071364)2.98175960
81rRNA metabolic process (GO:0016072)2.98062543
82translesion synthesis (GO:0019985)2.97932033
83activation of Rac GTPase activity (GO:0032863)2.97561266
84spliceosomal tri-snRNP complex assembly (GO:0000244)2.97018476
85negative regulation of fatty acid transport (GO:2000192)2.96545764
86regulation of early endosome to late endosome transport (GO:2000641)2.95180037
87nuclear envelope organization (GO:0006998)2.94583914
88DNA duplex unwinding (GO:0032508)2.93734044
89chromosome condensation (GO:0030261)2.93027208
90DNA geometric change (GO:0032392)2.92604636
91RNA stabilization (GO:0043489)2.91959648
92mRNA stabilization (GO:0048255)2.91959648
93histone H3-K36 demethylation (GO:0070544)2.91688372
94SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.90069857
95epithelial cell differentiation involved in prostate gland development (GO:0060742)2.87579377
96tetrahydrofolate metabolic process (GO:0046653)2.87482067
97nucleotide-excision repair, DNA gap filling (GO:0006297)2.86231015
98negative regulation of cell size (GO:0045792)2.85716148
99pteridine-containing compound biosynthetic process (GO:0042559)2.83792640
100protein complex localization (GO:0031503)2.81799436
101desmosome organization (GO:0002934)2.81013735
102protein targeting to ER (GO:0045047)2.80916983
103regulation of chromosome segregation (GO:0051983)2.80198392
104cotranslational protein targeting to membrane (GO:0006613)2.80130901
105cellular protein complex disassembly (GO:0043624)2.79705057
106maternal placenta development (GO:0001893)2.78943276
107chromatin assembly or disassembly (GO:0006333)2.78774068
108binding of sperm to zona pellucida (GO:0007339)2.77204957
109protein localization to chromosome (GO:0034502)2.77161364
110pseudouridine synthesis (GO:0001522)2.75244449
111pore complex assembly (GO:0046931)2.75050276
112negative regulation of chromosome segregation (GO:0051985)2.73630449
113folic acid-containing compound metabolic process (GO:0006760)2.73585369
114negative regulation of fibrinolysis (GO:0051918)2.73518546
115positive regulation of chromosome segregation (GO:0051984)2.73488412
116hemidesmosome assembly (GO:0031581)2.72850735
117viral life cycle (GO:0019058)2.72803214
118regulation of translational termination (GO:0006449)2.72260035
119response to laminar fluid shear stress (GO:0034616)2.72088601
120DNA conformation change (GO:0071103)2.71654916
121regulation of histone H3-K9 methylation (GO:0051570)2.69715253
122cellular hyperosmotic response (GO:0071474)2.68700443
123negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.68004765
124DNA packaging (GO:0006323)2.67528590
125stress fiber assembly (GO:0043149)2.67419733
126negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.67144360
127negative regulation of sister chromatid segregation (GO:0033046)2.67144360
128negative regulation of mitotic sister chromatid separation (GO:2000816)2.67144360
129negative regulation of mitotic sister chromatid segregation (GO:0033048)2.67144360
130positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.67112483
131establishment of chromosome localization (GO:0051303)2.66717842
132synaptonemal complex assembly (GO:0007130)2.66324661
133mitotic sister chromatid cohesion (GO:0007064)2.65800348
134regulation of translational fidelity (GO:0006450)2.65503533
135establishment of protein localization to endoplasmic reticulum (GO:0072599)2.65425360
136chaperone-mediated protein complex assembly (GO:0051131)2.64230560
137protein localization to endoplasmic reticulum (GO:0070972)2.63730688
138regulation of mitotic spindle organization (GO:0060236)2.63437913
139protein complex disassembly (GO:0043241)2.62668734
140insulin-like growth factor receptor signaling pathway (GO:0048009)2.62183206
141maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.61003086
142response to epidermal growth factor (GO:0070849)2.60663468
143L-serine metabolic process (GO:0006563)2.60205127
144spindle assembly checkpoint (GO:0071173)2.59324490
145basement membrane organization (GO:0071711)2.58385911
146protein retention in ER lumen (GO:0006621)2.57958256
147positive regulation of Cdc42 GTPase activity (GO:0043089)2.57573636
148modulation by symbiont of host cellular process (GO:0044068)2.57434522
149pentose-phosphate shunt (GO:0006098)2.56762573
150activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.54793656
151protein-lipid complex assembly (GO:0065005)2.53872287
152epithelial cell-cell adhesion (GO:0090136)2.53042797
153positive regulation of nuclease activity (GO:0032075)2.48770274
154positive regulation of extracellular matrix organization (GO:1903055)2.48371700
155skin morphogenesis (GO:0043589)2.47081635
156intracellular estrogen receptor signaling pathway (GO:0030520)2.47074066
157very-low-density lipoprotein particle assembly (GO:0034379)2.46998671
158hypotonic response (GO:0006971)2.46831393
159urea cycle (GO:0000050)2.45385656
160plasma lipoprotein particle assembly (GO:0034377)2.45306980
161regulation of extracellular matrix disassembly (GO:0010715)2.44656188
162protein export from nucleus (GO:0006611)2.42176531
163glucose 6-phosphate metabolic process (GO:0051156)2.40703681
164low-density lipoprotein particle clearance (GO:0034383)2.40664748
165cellular protein complex localization (GO:0034629)2.39228160
166glucocorticoid receptor signaling pathway (GO:0042921)2.37882059
167dicarboxylic acid biosynthetic process (GO:0043650)2.37284519
168positive regulation of myotube differentiation (GO:0010831)2.33964785
169peptidyl-lysine dimethylation (GO:0018027)2.33841315
170COPII vesicle coating (GO:0048208)2.33523946
171regulation of apoptotic cell clearance (GO:2000425)2.33305385
172regulation of cholesterol biosynthetic process (GO:0045540)2.31503569
173proline metabolic process (GO:0006560)2.30355306
174positive regulation of keratinocyte differentiation (GO:0045618)2.30229694
175planar cell polarity pathway involved in neural tube closure (GO:0090179)2.30194846
176regulation of extracellular matrix organization (GO:1903053)2.28740413
177barbed-end actin filament capping (GO:0051016)2.28540846
178regulation of nuclease activity (GO:0032069)2.27928327
179ER-nucleus signaling pathway (GO:0006984)2.27300410
180surfactant homeostasis (GO:0043129)2.25617599
181endoplasmic reticulum unfolded protein response (GO:0030968)2.25576778
182modulation by virus of host morphology or physiology (GO:0019048)2.25125076
183branching involved in mammary gland duct morphogenesis (GO:0060444)2.24449564
184negative regulation of viral release from host cell (GO:1902187)2.23542513
185positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.23370918
186NADH metabolic process (GO:0006734)2.22936558
187modulation by virus of host process (GO:0019054)2.22933358
188corticosteroid receptor signaling pathway (GO:0031958)2.22285207
189negative regulation of myotube differentiation (GO:0010832)2.22178114
190NADPH regeneration (GO:0006740)2.22174220
191positive regulation of blood vessel endothelial cell migration (GO:0043536)2.21392513
192histone lysine demethylation (GO:0070076)2.21330436
193peptidyl-threonine modification (GO:0018210)2.20978934
194urea metabolic process (GO:0019627)2.20943516

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.54370935
2FOXM1_23109430_ChIP-Seq_U2OS_Human3.99849278
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.93899572
4TP63_17297297_ChIP-ChIP_HaCaT_Human3.80414787
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.68120914
6MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.36405891
7E2F4_17652178_ChIP-ChIP_JURKAT_Human3.18096238
8FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.93833482
9MYC_19079543_ChIP-ChIP_MESCs_Mouse2.75705050
10MYC_18358816_ChIP-ChIP_MESCs_Mouse2.65122153
11MYC_19030024_ChIP-ChIP_MESCs_Mouse2.56873769
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.38009817
13JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.35578613
14KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.35156873
15EST1_17652178_ChIP-ChIP_JURKAT_Human2.31780195
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.29147961
17KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.26432785
18TCF7_22412390_ChIP-Seq_EML_Mouse2.25173950
19GABP_17652178_ChIP-ChIP_JURKAT_Human2.21216174
20LXR_22292898_ChIP-Seq_THP-1_Human2.20268125
21ELK3_25401928_ChIP-Seq_HUVEC_Human2.19464655
22XRN2_22483619_ChIP-Seq_HELA_Human2.18183431
23KDM2B_26808549_Chip-Seq_SUP-B15_Human2.16495733
24NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.15619935
25THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.10588907
26NELFA_20434984_ChIP-Seq_ESCs_Mouse2.06526293
27CLOCK_20551151_ChIP-Seq_293T_Human2.06087979
28AR_21909140_ChIP-Seq_LNCAP_Human2.05654765
29RARG_19884340_ChIP-ChIP_MEFs_Mouse2.04350531
30RACK7_27058665_Chip-Seq_MCF-7_Human2.03274092
31MYC_22102868_ChIP-Seq_BL_Human1.96934057
32EGR1_19374776_ChIP-ChIP_THP-1_Human1.93581133
33VDR_23849224_ChIP-Seq_CD4+_Human1.89892419
34KDM2B_26808549_Chip-Seq_DND41_Human1.85002470
35HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.82213389
36DCP1A_22483619_ChIP-Seq_HELA_Human1.81966844
37MYCN_18555785_ChIP-Seq_MESCs_Mouse1.80876842
38KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.80193010
39E2F1_21310950_ChIP-Seq_MCF-7_Human1.79233609
40CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.77060928
41FOXP3_21729870_ChIP-Seq_TREG_Human1.76992169
42ESR2_21235772_ChIP-Seq_MCF-7_Human1.74574573
43GABP_19822575_ChIP-Seq_HepG2_Human1.74076033
44NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.74034654
45EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.73709619
46E2F1_18555785_ChIP-Seq_MESCs_Mouse1.73050158
47PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.71078472
48SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.65907583
49KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.65787759
50TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.64410762
51POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.64201921
52KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.62482314
53MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.62410841
54TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.59080588
55ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.57076437
56STAT3_1855785_ChIP-Seq_MESCs_Mouse1.55230073
57TTF2_22483619_ChIP-Seq_HELA_Human1.55083782
58ZFX_18555785_ChIP-Seq_MESCs_Mouse1.54153403
59KDM2B_26808549_Chip-Seq_K562_Human1.53018756
60NANOG_18555785_ChIP-Seq_MESCs_Mouse1.52468548
61ZFP281_18757296_ChIP-ChIP_E14_Mouse1.50993454
62ELF1_17652178_ChIP-ChIP_JURKAT_Human1.50687324
63RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.50028444
64P300_27058665_Chip-Seq_ZR-75-30cells_Human1.49240058
65KDM5A_27292631_Chip-Seq_BREAST_Human1.47606387
66PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.45433042
67SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.43537227
68VDR_24763502_ChIP-Seq_THP-1_Human1.42779239
69WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.41252686
70KLF4_18555785_ChIP-Seq_MESCs_Mouse1.38746727
71CIITA_25753668_ChIP-Seq_RAJI_Human1.37857110
72STAT6_21828071_ChIP-Seq_BEAS2B_Human1.36924895
73TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.36685584
74TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.36014473
75ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.34428497
76THAP11_20581084_ChIP-Seq_MESCs_Mouse1.33364218
77KDM2B_26808549_Chip-Seq_JURKAT_Human1.33151981
78VDR_21846776_ChIP-Seq_THP-1_Human1.31045019
79SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.30604546
80ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.30603289
81NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.30438783
82KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.29904677
83DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.29323382
84YY1_21170310_ChIP-Seq_MESCs_Mouse1.28863830
85TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.27982828
86ATF3_27146783_Chip-Seq_COLON_Human1.27829047
87PPARA_22158963_ChIP-Seq_LIVER_Mouse1.27824511
88SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.26279856
89TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.24922328
90CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.24890117
91RXR_22158963_ChIP-Seq_LIVER_Mouse1.24036686
92SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.22198415
93UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.21940582
94POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.21512628
95RUNX1_22412390_ChIP-Seq_EML_Mouse1.20753120
96CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.20732326
97HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.20369723
98FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.19823530
99RUNX1_27514584_Chip-Seq_MCF-7_Human1.19486198
100CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.19192146
101EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.19174965
102DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.18790007
103FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.18368118
104E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.18067841
105ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.16640000
106HOXB4_20404135_ChIP-ChIP_EML_Mouse1.15697471
107ERG_20887958_ChIP-Seq_HPC-7_Mouse1.15683476
108ZFP281_27345836_Chip-Seq_ESCs_Mouse1.15577923
109CTCF_27219007_Chip-Seq_ERYTHROID_Human1.15546417
110NCOR1_26117541_ChIP-Seq_K562_Human1.14199313
111SMC4_20622854_ChIP-Seq_HELA_Human1.13467197
112KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.11295599
113CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.11096308
114TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.11002469
115MAF_26560356_Chip-Seq_TH2_Human1.10872136
116NOTCH1_21737748_ChIP-Seq_TLL_Human1.10488960
117UBF1/2_26484160_Chip-Seq_HMECs_Human1.09983520
118E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.09809693
119CREB1_26743006_Chip-Seq_LNCaP_Human1.09745306
120CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.09316276
121TFEB_21752829_ChIP-Seq_HELA_Human1.09136867
122SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.09040569
123SOX2_27498859_Chip-Seq_STOMACH_Mouse1.08747750
124SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.07603827
125TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.06789037
126SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.06627453
127ELK1_19687146_ChIP-ChIP_HELA_Human1.06504861
128YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.04646735
129CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.04293588
130GATA1_19941827_ChIP-Seq_MEL_Mouse1.04164525
131ESR1_15608294_ChIP-ChIP_MCF-7_Human1.03737720
132TP53_22127205_ChIP-Seq_IMR90_Human1.02090360
133SOX9_24532713_ChIP-Seq_HFSC_Mouse1.01020968
134P68_20966046_ChIP-Seq_HELA_Human1.00359350
135MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.00117939
136TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.99713254
137TBX20_22080862_ChIP-Seq_HEART_Mouse0.99309057
138TBX20_22328084_ChIP-Seq_HEART_Mouse0.99309057
139ESR1_21235772_ChIP-Seq_MCF-7_Human0.99257280
140SRF_21415370_ChIP-Seq_HL-1_Mouse0.98693243
141NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.98544191
142SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.97986311
143SA1_27219007_Chip-Seq_ERYTHROID_Human0.97851426
144MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.97581940
145TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.97227349
146CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.97160196
147RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.96716778
148CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.96368458
149TET1_21451524_ChIP-Seq_MESCs_Mouse0.96360966
150ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.96241818
151ERG_21242973_ChIP-ChIP_JURKAT_Human0.96064990
152CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.95592112
153E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.94693723
154SPI1_23547873_ChIP-Seq_NB4_Human0.93691945
155ZNF263_19887448_ChIP-Seq_K562_Human0.92626855
156POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.89316533
157CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.88415933
158HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.88316774
159MYB_21317192_ChIP-Seq_ERMYB_Mouse0.87804023
160SOX2_18555785_ChIP-Seq_MESCs_Mouse0.87661509
161BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.86880931
162PADI4_21655091_ChIP-ChIP_MCF-7_Human0.85983648
163GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.85327786
164KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.83203994
165NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.81935048
166UTX_26944678_Chip-Seq_JUKART_Human0.81111714
167TP63_19390658_ChIP-ChIP_HaCaT_Human0.80800054
168MYB_26560356_Chip-Seq_TH1_Human0.80514660
169MAF_26560356_Chip-Seq_TH1_Human0.80097279
170NANOG_21062744_ChIP-ChIP_HESCs_Human0.80036049
171BRD4_27068464_Chip-Seq_AML-cells_Mouse0.78588814
172GATA1_22383799_ChIP-Seq_G1ME_Mouse0.77684255
173KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.77607189

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.61538916
2MP0003111_abnormal_nucleus_morphology3.95625270
3MP0004957_abnormal_blastocyst_morpholog3.87505045
4MP0010094_abnormal_chromosome_stability3.85621107
5MP0005451_abnormal_body_composition3.74910189
6MP0003077_abnormal_cell_cycle3.36740661
7MP0008057_abnormal_DNA_replication3.20862081
8MP0010234_abnormal_vibrissa_follicle2.67868765
9MP0008058_abnormal_DNA_repair2.61091196
10MP0002877_abnormal_melanocyte_morpholog2.49380229
11MP0008007_abnormal_cellular_replicative2.40272487
12MP0004185_abnormal_adipocyte_glucose2.34485528
13MP0005409_darkened_coat_color2.33608381
14MP0005410_abnormal_fertilization2.27370495
15MP0001730_embryonic_growth_arrest2.25270435
16MP0004233_abnormal_muscle_weight2.22823223
17MP0002396_abnormal_hematopoietic_system2.20591004
18MP0005058_abnormal_lysosome_morphology2.20089914
19MP0010352_gastrointestinal_tract_polyps2.13673783
20MP0003806_abnormal_nucleotide_metabolis2.13643195
21MP0008932_abnormal_embryonic_tissue2.07159101
22MP0000350_abnormal_cell_proliferation2.00663178
23MP0010307_abnormal_tumor_latency1.97067551
24MP0008260_abnormal_autophagy1.95807810
25MP0003453_abnormal_keratinocyte_physiol1.90905478
26MP0003091_abnormal_cell_migration1.86211433
27MP0008877_abnormal_DNA_methylation1.84717462
28MP0000490_abnormal_crypts_of1.74222758
29MP0008438_abnormal_cutaneous_collagen1.69855887
30MP0003786_premature_aging1.68046054
31MP0003191_abnormal_cellular_cholesterol1.67234935
32MP0009840_abnormal_foam_cell1.66060527
33MP0001672_abnormal_embryogenesis/_devel1.63694163
34MP0005380_embryogenesis_phenotype1.63694163
35MP0002796_impaired_skin_barrier1.63165552
36MP0001929_abnormal_gametogenesis1.62686670
37MP0001697_abnormal_embryo_size1.57887002
38MP0003172_abnormal_lysosome_physiology1.55179584
39MP0002080_prenatal_lethality1.53807622
40MP0004808_abnormal_hematopoietic_stem1.53794648
41MP0002210_abnormal_sex_determination1.51165481
42MP0003984_embryonic_growth_retardation1.50535460
43MP0002088_abnormal_embryonic_growth/wei1.48210157
44MP0003123_paternal_imprinting1.47307049
45MP0005397_hematopoietic_system_phenotyp1.44387991
46MP0001545_abnormal_hematopoietic_system1.44387991
47MP0004947_skin_inflammation1.42566693
48MP0002019_abnormal_tumor_incidence1.42103436
49MP0005666_abnormal_adipose_tissue1.41970929
50MP0009333_abnormal_splenocyte_physiolog1.41887124
51MP0005257_abnormal_intraocular_pressure1.40922497
52MP0002009_preneoplasia1.40216949
53MP0001145_abnormal_male_reproductive1.39613832
54MP0000313_abnormal_cell_death1.37684512
55MP0000751_myopathy1.36458326
56MP0003705_abnormal_hypodermis_morpholog1.35973323
57MP0002089_abnormal_postnatal_growth/wei1.35912734
58MP0000733_abnormal_muscle_development1.35019550
59MP0002086_abnormal_extraembryonic_tissu1.34909254
60MP0001348_abnormal_lacrimal_gland1.34805558
61MP0001661_extended_life_span1.32349622
62MP0004858_abnormal_nervous_system1.32165201
63MP0000747_muscle_weakness1.31777603
64MP0002166_altered_tumor_susceptibility1.31015662
65MP0002085_abnormal_embryonic_tissue1.30769096
66MP0000003_abnormal_adipose_tissue1.28194142
67MP0004087_abnormal_muscle_fiber1.27874600
68MP0002139_abnormal_hepatobiliary_system1.27633745
69MP0005076_abnormal_cell_differentiation1.25225412
70MP0002084_abnormal_developmental_patter1.24851072
71MP0005375_adipose_tissue_phenotype1.23043187
72MP0010630_abnormal_cardiac_muscle1.22558856
73MP0004197_abnormal_fetal_growth/weight/1.20693549
74MP0002060_abnormal_skin_morphology1.20473544
75MP0003718_maternal_effect1.19601928
76MP0005360_urolithiasis1.19243471
77MP0003763_abnormal_thymus_physiology1.17333206
78MP0003698_abnormal_male_reproductive1.16306857
79MP0000759_abnormal_skeletal_muscle1.15162139
80MP0000653_abnormal_sex_gland1.13548506
81MP0002398_abnormal_bone_marrow1.12055276
82MP0002722_abnormal_immune_system1.10780820
83MP0000689_abnormal_spleen_morphology1.10267988
84MP0004272_abnormal_basement_membrane1.09357822
85MP0000358_abnormal_cell_content/1.08737308
86MP0000703_abnormal_thymus_morphology1.06970663
87MP0003941_abnormal_skin_development1.05580281
88MP0002653_abnormal_ependyma_morphology1.05280141
89MP0009278_abnormal_bone_marrow1.05248153
90MP0003567_abnormal_fetal_cardiomyocyte1.03971133
91MP0003329_amyloid_beta_deposits1.03184653
92MP0002132_abnormal_respiratory_system0.99521283
93MP0001216_abnormal_epidermal_layer0.99477332
94MP0002269_muscular_atrophy0.98420711
95MP0000579_abnormal_nail_morphology0.98296844
96MP0001293_anophthalmia0.96728322
97MP0004381_abnormal_hair_follicle0.96571823
98MP0000537_abnormal_urethra_morphology0.96445646
99MP0005023_abnormal_wound_healing0.95368237
100MP0003186_abnormal_redox_activity0.92116448
101MP0000858_altered_metastatic_potential0.91945994
102MP0009672_abnormal_birth_weight0.91719215
103MP0002429_abnormal_blood_cell0.90385854
104MP0003303_peritoneal_inflammation0.88025479
105MP0009053_abnormal_anal_canal0.87524239
106MP0000685_abnormal_immune_system0.87410293
107MP0002998_abnormal_bone_remodeling0.86965914
108MP0000598_abnormal_liver_morphology0.86849371
109MP0003221_abnormal_cardiomyocyte_apopto0.85841938
110MP0002006_tumorigenesis0.84670447
111MP0002161_abnormal_fertility/fecundity0.83248367
112MP0000767_abnormal_smooth_muscle0.83203350
113MP0003436_decreased_susceptibility_to0.81782807
114MP0005623_abnormal_meninges_morphology0.81629552
115MP0003656_abnormal_erythrocyte_physiolo0.81180732
116MP0006054_spinal_hemorrhage0.80620073
117MP0009931_abnormal_skin_appearance0.80405383
118MP0000467_abnormal_esophagus_morphology0.79842168
119MP0003115_abnormal_respiratory_system0.79736343
120MP0000678_abnormal_parathyroid_gland0.79382806
121MP0010030_abnormal_orbit_morphology0.79030056
122MP0005464_abnormal_platelet_physiology0.78793637
123MP0001915_intracranial_hemorrhage0.78306954
124MP0003828_pulmonary_edema0.77477290
125MP0000716_abnormal_immune_system0.77293649
126MP0005330_cardiomyopathy0.76937484
127MP0003566_abnormal_cell_adhesion0.76205428
128MP0000609_abnormal_liver_physiology0.76084981
129MP0006138_congestive_heart_failure0.75873405
130MP0002405_respiratory_system_inflammati0.74157349
131MP0000477_abnormal_intestine_morphology0.74093737
132MP0002160_abnormal_reproductive_system0.73287532
133MP0001958_emphysema0.72193378
134MP0005384_cellular_phenotype0.72173465
135MP0002896_abnormal_bone_mineralization0.72152892
136MP0006036_abnormal_mitochondrial_physio0.71625203
137MP0001851_eye_inflammation0.71376059
138MP0005621_abnormal_cell_physiology0.71328132
139MP0004264_abnormal_extraembryonic_tissu0.69499960
140MP0009780_abnormal_chondrocyte_physiolo0.69346520
141MP0002092_abnormal_eye_morphology0.69202816
142MP0005365_abnormal_bile_salt0.68984123
143MP0001800_abnormal_humoral_immune0.68954806
144MP0000377_abnormal_hair_follicle0.68821224
145MP0004130_abnormal_muscle_cell0.68138717
146MP0005501_abnormal_skin_physiology0.66337227
147MP0005085_abnormal_gallbladder_physiolo0.65085230
148MP0001853_heart_inflammation0.64407097
149MP0003890_abnormal_embryonic-extraembry0.63581377
150MP0003300_gastrointestinal_ulcer0.62974158
151MP0001849_ear_inflammation0.62725147
152MP0005319_abnormal_enzyme/_coenzyme0.62083229
153MP0006035_abnormal_mitochondrial_morpho0.60683522
154MP0010155_abnormal_intestine_physiology0.59573941
155MP0001119_abnormal_female_reproductive0.59162190
156MP0002970_abnormal_white_adipose0.56368729
157MP0002452_abnormal_antigen_presenting0.56289616
158MP0003448_altered_tumor_morphology0.56210879

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)3.99311169
2Abnormality of cells of the erythroid lineage (HP:0012130)3.90458345
3Abnormal number of erythroid precursors (HP:0012131)3.79842629
4Birth length less than 3rd percentile (HP:0003561)3.69100605
5Deep venous thrombosis (HP:0002625)3.61150880
6Breast hypoplasia (HP:0003187)3.56831041
7Oral leukoplakia (HP:0002745)3.47587125
8Degeneration of anterior horn cells (HP:0002398)3.43634246
9Abnormality of the anterior horn cell (HP:0006802)3.43634246
10Selective tooth agenesis (HP:0001592)3.42167450
11Impulsivity (HP:0100710)3.30687338
12Multiple enchondromatosis (HP:0005701)3.12252887
13Hyperacusis (HP:0010780)3.10622978
14Ependymoma (HP:0002888)2.97149864
15Macrocytic anemia (HP:0001972)2.88985225
16Asymmetry of the thorax (HP:0001555)2.88069126
17Flat acetabular roof (HP:0003180)2.87019649
18Abnormality of pyrimidine metabolism (HP:0004353)2.84840366
19Nasal polyposis (HP:0100582)2.82369214
20Centrally nucleated skeletal muscle fibers (HP:0003687)2.80511366
21Protrusio acetabuli (HP:0003179)2.78608975
22Rough bone trabeculation (HP:0100670)2.74762860
23Abnormal spermatogenesis (HP:0008669)2.70847138
24Trismus (HP:0000211)2.69172456
25Increased connective tissue (HP:0009025)2.65672747
26Carpal bone hypoplasia (HP:0001498)2.63642940
27Pallor (HP:0000980)2.63557811
28Exercise-induced myalgia (HP:0003738)2.57433779
29Broad face (HP:0000283)2.57079649
30Distal lower limb amyotrophy (HP:0008944)2.56602825
31Rhabdomyosarcoma (HP:0002859)2.52827393
32Cerebral aneurysm (HP:0004944)2.47308193
33Microretrognathia (HP:0000308)2.45256127
34Absent thumb (HP:0009777)2.44265623
35Colon cancer (HP:0003003)2.43684962
36Progressive muscle weakness (HP:0003323)2.43680994
37Basal cell carcinoma (HP:0002671)2.42478167
38Abnormality of chromosome stability (HP:0003220)2.42009742
39Dysmetric saccades (HP:0000641)2.41352045
40Thrombocytosis (HP:0001894)2.39429169
41Patellar aplasia (HP:0006443)2.39423186
42Ankyloglossia (HP:0010296)2.39290617
43Chromsome breakage (HP:0040012)2.37114663
44Abnormality of the nasal mucosa (HP:0000433)2.32403889
45Neoplasm of the pancreas (HP:0002894)2.32017607
46Abnormality of reticulocytes (HP:0004312)2.31294924
47Achilles tendon contracture (HP:0001771)2.31178050
48Prominent nose (HP:0000448)2.29452527
49Premature ovarian failure (HP:0008209)2.29031628
50Abnormality of the preputium (HP:0100587)2.28774700
51Agnosia (HP:0010524)2.28215946
52Secondary amenorrhea (HP:0000869)2.28129369
53Myelodysplasia (HP:0002863)2.27112458
54Atrophy/Degeneration involving motor neurons (HP:0007373)2.26959060
55Aplastic anemia (HP:0001915)2.26702612
56Chromosomal breakage induced by crosslinking agents (HP:0003221)2.26617934
57Abnormality of the Achilles tendon (HP:0005109)2.26320346
58Distal lower limb muscle weakness (HP:0009053)2.24528990
59Meckel diverticulum (HP:0002245)2.24238279
60Aplasia/Hypoplasia of the patella (HP:0006498)2.23820289
61Entropion (HP:0000621)2.23319440
62Medulloblastoma (HP:0002885)2.21529561
63Hemorrhage of the eye (HP:0011885)2.19994855
64Premature rupture of membranes (HP:0001788)2.19222603
6511 pairs of ribs (HP:0000878)2.18199086
66Squamous cell carcinoma (HP:0002860)2.17608575
67Ulnar bowing (HP:0003031)2.17243295
68Megaloblastic anemia (HP:0001889)2.14366686
69Abnormality of oral frenula (HP:0000190)2.13411403
70Abnormality of the ileum (HP:0001549)2.12707697
71Chronic bronchitis (HP:0004469)2.10905926
72Aplasia/Hypoplasia of the uvula (HP:0010293)2.10487419
73Abnormality of skeletal muscle fiber size (HP:0012084)2.07583975
74Vertebral compression fractures (HP:0002953)2.07215109
75Advanced eruption of teeth (HP:0006288)2.06119175
76Cerebral hypomyelination (HP:0006808)2.03739604
77Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.03726849
78Sloping forehead (HP:0000340)2.03360353
79Increased variability in muscle fiber diameter (HP:0003557)2.03196926
80Thin bony cortex (HP:0002753)2.03149883
81Personality changes (HP:0000751)2.02207623
82Abnormality of monocarboxylic acid metabolism (HP:0010996)1.99276222
83Insomnia (HP:0100785)1.98802932
84Hypobetalipoproteinemia (HP:0003563)1.98084664
85Bone marrow hypocellularity (HP:0005528)1.97906714
86Disproportionate tall stature (HP:0001519)1.96349824
87Abnormality of the fingertips (HP:0001211)1.96241749
88Hypoplasia of the capital femoral epiphysis (HP:0003090)1.95457491
89Absent radius (HP:0003974)1.95126268
90Bronchitis (HP:0012387)1.94306093
91Neoplasm of striated muscle (HP:0009728)1.94139810
92Spastic diplegia (HP:0001264)1.93563979
93Myopathic facies (HP:0002058)1.92481974
94Back pain (HP:0003418)1.90856544
95Atresia of the external auditory canal (HP:0000413)1.90287609
96Proximal placement of thumb (HP:0009623)1.90162318
97High pitched voice (HP:0001620)1.90052775
98Premature graying of hair (HP:0002216)1.87306983
99Duodenal stenosis (HP:0100867)1.86933733
100Small intestinal stenosis (HP:0012848)1.86933733
101Subacute progressive viral hepatitis (HP:0006572)1.86871275
102Abnormal ossification of hand bones (HP:0005921)1.86811670
103Syringomyelia (HP:0003396)1.85065377
104Spinal cord lesions (HP:0100561)1.85065377
105Sparse lateral eyebrow (HP:0005338)1.84619046
106Type 1 muscle fiber predominance (HP:0003803)1.84174749
107Horseshoe kidney (HP:0000085)1.83683136
108Recurrent bronchitis (HP:0002837)1.83239538
109Dislocated radial head (HP:0003083)1.83115202
110Lower limb amyotrophy (HP:0007210)1.82957304
111Aplasia/Hypoplasia of the sacrum (HP:0008517)1.82131823
112Deviation of the thumb (HP:0009603)1.81864782
113Abnormality of carpal bone ossification (HP:0006257)1.81797057
114Pancytopenia (HP:0001876)1.81726601
115Missing ribs (HP:0000921)1.81713516
116Abnormal trabecular bone morphology (HP:0100671)1.81018679
117Cleft eyelid (HP:0000625)1.80798081
118Tracheoesophageal fistula (HP:0002575)1.80709033
119Azoospermia (HP:0000027)1.80559639
120Colitis (HP:0002583)1.77630980
121Ureteral duplication (HP:0000073)1.77328777
122Abnormality of the common coagulation pathway (HP:0010990)1.76846359
123Right ventricular cardiomyopathy (HP:0011663)1.76132137
124Osteolytic defects of the hand bones (HP:0009699)1.75662342
125Osteolytic defects of the phalanges of the hand (HP:0009771)1.75662342
126Facial hemangioma (HP:0000329)1.75480318
127Muscle fiber inclusion bodies (HP:0100299)1.75391837
128Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.75194928
129Abnormality of the thoracic spine (HP:0100711)1.75087337
130Absent forearm bone (HP:0003953)1.74152743
131Aplasia involving forearm bones (HP:0009822)1.74152743
132Nemaline bodies (HP:0003798)1.73929041
133Obstructive sleep apnea (HP:0002870)1.73819652
134Ectopic kidney (HP:0000086)1.73146795
135Cafe-au-lait spot (HP:0000957)1.73021047
136Cellular immunodeficiency (HP:0005374)1.72567485
137Progressive external ophthalmoplegia (HP:0000590)1.72358871
138Overlapping toe (HP:0001845)1.71740609
139Aneurysm (HP:0002617)1.71316627
140Increased nuchal translucency (HP:0010880)1.70920599
141Poikiloderma (HP:0001029)1.70759954
142Mildly elevated creatine phosphokinase (HP:0008180)1.70136077
143Cellulitis (HP:0100658)1.69936431
144Hypercholesterolemia (HP:0003124)1.69864961
145Cerebral inclusion bodies (HP:0100314)1.69335864
146Supernumerary spleens (HP:0009799)1.68855581
147Myocardial infarction (HP:0001658)1.68841227
148Insidious onset (HP:0003587)1.68497673
149Termporal pattern (HP:0011008)1.68497673
150Arterial tortuosity (HP:0005116)1.68420764
151Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.67816752
152Reduced antithrombin III activity (HP:0001976)1.67708291
153Amaurosis fugax (HP:0100576)1.67310225
154Long palpebral fissure (HP:0000637)1.66369091
155Abnormality of the radial head (HP:0003995)1.66265812
156Sparse eyelashes (HP:0000653)1.66227752
157Abnormality of the calcaneus (HP:0008364)1.65779128
158Increased serum ferritin (HP:0003281)1.65392613
159Heterotopia (HP:0002282)1.64880420
160IgM deficiency (HP:0002850)1.64592467
161Esophageal varix (HP:0002040)1.63125247
162Abnormality of the distal phalanx of the thumb (HP:0009617)1.63073756
163Slender long bone (HP:0003100)1.62824856
164Eczematoid dermatitis (HP:0000976)1.62741086
165Lymphoma (HP:0002665)1.62490001
166Biconcave vertebral bodies (HP:0004586)1.62477674
167Polygenic inheritance (HP:0010982)1.59191107
168Natal tooth (HP:0000695)1.58883133
169Upper limb amyotrophy (HP:0009129)1.58514222
170Distal upper limb amyotrophy (HP:0007149)1.58514222
171Mitral regurgitation (HP:0001653)1.58447556
172Mitral valve prolapse (HP:0001634)1.58281504
173Ulnar deviation of the wrist (HP:0003049)1.58118533
174Segmental peripheral demyelination/remyelination (HP:0003481)1.57990442
175Cupped ribs (HP:0000887)1.57976411
176Abnormality of nail color (HP:0100643)1.57873937
177Shallow orbits (HP:0000586)1.57689213
178Vertebral arch anomaly (HP:0008438)1.57360080
179Spinal rigidity (HP:0003306)1.57208786
180Abnormality of the salivary glands (HP:0010286)1.56995407
181Fragile skin (HP:0001030)1.56619734
182Abnormality of complement system (HP:0005339)1.56448205
183Hyporeflexia of lower limbs (HP:0002600)1.54575561
184Renal duplication (HP:0000075)1.53291862
185Cervical subluxation (HP:0003308)1.52832037
186Arnold-Chiari malformation (HP:0002308)1.52480919
187Germ cell neoplasia (HP:0100728)1.51950911
188Dilatation of the ascending aorta (HP:0005111)1.50544019
189Asymmetric septal hypertrophy (HP:0001670)1.49986799
190Wormian bones (HP:0002645)1.49227136
191Abnormal foot bone ossification (HP:0010675)1.49010758
192Blue sclerae (HP:0000592)1.48400456
193Vascular tortuosity (HP:0004948)1.48249186
194Viral hepatitis (HP:0006562)1.47488360
195Round ear (HP:0100830)1.47232484
196Fatigue (HP:0012378)1.47224627
197Ragged-red muscle fibers (HP:0003200)1.46726671
198Metaphyseal cupping (HP:0003021)1.46295106

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.25486278
2WEE13.90747961
3SMG13.69867659
4CDC73.36963037
5PRPF4B3.32614611
6NEK23.22226136
7EIF2AK12.94605745
8TTN2.50205305
9SIK12.34453006
10NME22.29939178
11TESK22.15689107
12TTK2.13660517
13PDK42.09603228
14PDK32.09603228
15EEF2K2.04769952
16RIPK12.02911566
17PDGFRA1.91140695
18DYRK31.85065920
19PKN21.84862300
20TESK11.84115859
21ACVR1B1.83564714
22IRAK31.79576340
23CDK121.75748874
24RPS6KA41.75512674
25TLK11.72810233
26EIF2AK31.67173138
27NEK11.66635908
28PLK11.65962320
29MAP3K101.61566732
30FLT31.59670754
31CDK71.59468117
32TRIB31.58321687
33STK101.58165261
34BRSK21.57744763
35SRPK11.56269632
36CDK41.51160368
37MAP3K131.47261245
38RPS6KB21.46594802
39FGFR31.46409218
40MAP3K81.44460977
41MAP4K11.41215827
42SCYL21.40150654
43AURKB1.39935824
44PLK41.37781992
45KSR21.35287547
46ATR1.31735303
47PASK1.28771639
48CHEK21.26982457
49TSSK61.19534759
50BRD41.19009451
51MST1R1.18203021
52PAK41.15523578
53EPHA21.14728755
54MAP2K31.12900444
55STK161.10304480
56BCKDK1.08767830
57CHEK11.08731602
58AURKA1.08450836
59MAP3K141.07099920
60PDK21.03127119
61MAP3K111.00718097
62STK40.98564534
63PIM20.98197546
64VRK10.97596471
65PIM10.97376810
66CDC42BPA0.97280376
67CAMK1D0.95822502
68STK30.95117000
69RIPK40.93015194
70PTK60.92961468
71RET0.91770989
72PDPK10.91088713
73GRK60.90201686
74EPHB10.86688348
75LRRK20.84881175
76MKNK10.84537543
77BRSK10.84453952
78ZAP700.84129798
79ICK0.83696963
80MARK20.82941604
81MAP3K10.82820751
82KDR0.82614528
83CDK60.80574066
84TGFBR10.79664790
85MAPKAPK30.78468137
86MAP3K90.78023158
87TYRO30.74834521
88PAK10.73755398
89CAMK1G0.70497337
90ATM0.70298316
91CDK20.69806543
92ALK0.69758834
93PTK20.69750167
94RPS6KA20.68551850
95SGK30.68270176
96ERN10.67118179
97BLK0.66745281
98MTOR0.64546241
99PLK30.63686168
100MKNK20.63448725
101CCNB10.62799089
102MAPK120.60764959
103CSF1R0.60648934
104JAK10.59850717
105MAP3K70.59028984
106PDK10.57910424
107MAP3K60.57817892
108DYRK1B0.57707513
109PDGFRB0.56064305
110MAP2K20.55199404
111CSNK2A20.54673900
112MAP3K20.54543454
113RPS6KL10.54302217
114RPS6KC10.54302217
115TRPM70.54166773
116NEK90.54034710
117MAP3K30.53399180
118SIK20.52057958
119NTRK10.51291448
120PAK20.50950321
121JAK30.50099071
122MET0.49489399
123PRKD20.48499605
124PRKD30.48095281
125CSNK2A10.47898886
126BTK0.47538528
127CDK90.46823551
128BMX0.46660113
129DDR20.44556919
130TAOK10.43190551
131AKT20.41662810
132RPS6KB10.41610572
133CDK10.41377645
134CDK80.41263408
135MAPK110.40503779
136TBK10.40304995
137MELK0.40177859
138LATS20.40005459
139ARAF0.38926484
140WNK10.38083960
141HIPK20.36533588
142IRAK40.36286920
143RPS6KA50.36174404
144MAP3K50.35687346
145LATS10.34721835
146TYK20.34036642
147FGR0.33983376
148LMTK20.33536968
149MAPK100.33140233
150TAOK20.32736187
151RPS6KA10.32674363
152NEK60.31627652
153CAMKK10.31385542
154MAPKAPK20.29575295
155RPS6KA60.29573452
156IRAK20.29156437
157CSK0.28843204
158EIF2AK20.28306651
159PRKCI0.27087536
160BRAF0.25239115
161CLK10.24635286
162ZAK0.24184215
163FGFR40.22901101
164STK38L0.21975897

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.50112382
2Mismatch repair_Homo sapiens_hsa034303.54780354
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.35733562
4Ribosome_Homo sapiens_hsa030103.00786435
5RNA transport_Homo sapiens_hsa030132.93417668
6One carbon pool by folate_Homo sapiens_hsa006702.90768559
7Spliceosome_Homo sapiens_hsa030402.77288596
8Base excision repair_Homo sapiens_hsa034102.62567151
9RNA polymerase_Homo sapiens_hsa030202.49335946
10Homologous recombination_Homo sapiens_hsa034402.42200993
11Proteasome_Homo sapiens_hsa030502.41596312
12Cell cycle_Homo sapiens_hsa041102.37236565
13Nucleotide excision repair_Homo sapiens_hsa034202.34528796
14Pyrimidine metabolism_Homo sapiens_hsa002402.24586009
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.15704138
16Other glycan degradation_Homo sapiens_hsa005112.09978294
17Non-small cell lung cancer_Homo sapiens_hsa052232.03701762
18Vitamin B6 metabolism_Homo sapiens_hsa007502.00019515
19Selenocompound metabolism_Homo sapiens_hsa004501.72669423
20Pancreatic cancer_Homo sapiens_hsa052121.70929701
21Fanconi anemia pathway_Homo sapiens_hsa034601.70731807
22Endometrial cancer_Homo sapiens_hsa052131.63155468
23Pentose phosphate pathway_Homo sapiens_hsa000301.62657535
24Basal transcription factors_Homo sapiens_hsa030221.59291460
25Sulfur relay system_Homo sapiens_hsa041221.55385811
26mRNA surveillance pathway_Homo sapiens_hsa030151.53454432
27VEGF signaling pathway_Homo sapiens_hsa043701.49274392
28p53 signaling pathway_Homo sapiens_hsa041151.47481571
29Cysteine and methionine metabolism_Homo sapiens_hsa002701.46868124
30Folate biosynthesis_Homo sapiens_hsa007901.46300191
31Biosynthesis of amino acids_Homo sapiens_hsa012301.44133220
32Thyroid hormone signaling pathway_Homo sapiens_hsa049191.42739597
33RNA degradation_Homo sapiens_hsa030181.39191771
34Insulin signaling pathway_Homo sapiens_hsa049101.37673983
35Renal cell carcinoma_Homo sapiens_hsa052111.35920672
36AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.35158807
37Prion diseases_Homo sapiens_hsa050201.33503735
38Glioma_Homo sapiens_hsa052141.30554726
39Cyanoamino acid metabolism_Homo sapiens_hsa004601.29443809
40Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.29072216
41Drug metabolism - other enzymes_Homo sapiens_hsa009831.25381148
42Non-homologous end-joining_Homo sapiens_hsa034501.24917668
43Neurotrophin signaling pathway_Homo sapiens_hsa047221.23394779
44Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.23304143
45Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.21953841
46Systemic lupus erythematosus_Homo sapiens_hsa053221.21788919
47Adherens junction_Homo sapiens_hsa045201.19709516
48Notch signaling pathway_Homo sapiens_hsa043301.17919361
49Prostate cancer_Homo sapiens_hsa052151.17225141
50Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.16988878
51Proteoglycans in cancer_Homo sapiens_hsa052051.16605814
52ErbB signaling pathway_Homo sapiens_hsa040121.16112908
53Focal adhesion_Homo sapiens_hsa045101.13747376
54Insulin resistance_Homo sapiens_hsa049311.10276882
55Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.09029190
56Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.05166929
57Carbon metabolism_Homo sapiens_hsa012001.05140585
58Purine metabolism_Homo sapiens_hsa002301.04664932
59Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.03422558
60Phosphatidylinositol signaling system_Homo sapiens_hsa040701.02888380
61Antigen processing and presentation_Homo sapiens_hsa046120.99731450
62Epstein-Barr virus infection_Homo sapiens_hsa051690.99618923
63Adipocytokine signaling pathway_Homo sapiens_hsa049200.99235533
64Hepatitis C_Homo sapiens_hsa051600.98654177
65Leukocyte transendothelial migration_Homo sapiens_hsa046700.98194061
66Colorectal cancer_Homo sapiens_hsa052100.97690090
67Prolactin signaling pathway_Homo sapiens_hsa049170.97480570
68Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.96314676
69GnRH signaling pathway_Homo sapiens_hsa049120.95486529
70Longevity regulating pathway - mammal_Homo sapiens_hsa042110.95260234
71AMPK signaling pathway_Homo sapiens_hsa041520.94975426
72Inositol phosphate metabolism_Homo sapiens_hsa005620.93005407
73Herpes simplex infection_Homo sapiens_hsa051680.92817299
74Amoebiasis_Homo sapiens_hsa051460.92574485
75Choline metabolism in cancer_Homo sapiens_hsa052310.92560064
76Viral carcinogenesis_Homo sapiens_hsa052030.89716865
77Complement and coagulation cascades_Homo sapiens_hsa046100.88780334
78Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.88226478
79Estrogen signaling pathway_Homo sapiens_hsa049150.87432302
80Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.85996044
81Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.83701507
82Toxoplasmosis_Homo sapiens_hsa051450.83357159
83Osteoclast differentiation_Homo sapiens_hsa043800.83007172
84T cell receptor signaling pathway_Homo sapiens_hsa046600.80016001
85Phospholipase D signaling pathway_Homo sapiens_hsa040720.77671605
86Glycosaminoglycan degradation_Homo sapiens_hsa005310.76249690
87Glutathione metabolism_Homo sapiens_hsa004800.74595777
88Toll-like receptor signaling pathway_Homo sapiens_hsa046200.74174485
89Oocyte meiosis_Homo sapiens_hsa041140.73371881
90Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.72641994
91Glucagon signaling pathway_Homo sapiens_hsa049220.72371605
92Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.71306964
93Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.68392767
94Long-term potentiation_Homo sapiens_hsa047200.68033872
95Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.67699723
962-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.67445725
97Thyroid cancer_Homo sapiens_hsa052160.66865732
98TNF signaling pathway_Homo sapiens_hsa046680.66795559
99FoxO signaling pathway_Homo sapiens_hsa040680.66397522
100Sphingolipid signaling pathway_Homo sapiens_hsa040710.66213154
101Legionellosis_Homo sapiens_hsa051340.65536410
102ECM-receptor interaction_Homo sapiens_hsa045120.65259420
103Fatty acid biosynthesis_Homo sapiens_hsa000610.64262740
104Pyruvate metabolism_Homo sapiens_hsa006200.63994568
105Fructose and mannose metabolism_Homo sapiens_hsa000510.63909723
106Leishmaniasis_Homo sapiens_hsa051400.61235432
107Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.60739853
108Regulation of actin cytoskeleton_Homo sapiens_hsa048100.60660374
109HTLV-I infection_Homo sapiens_hsa051660.60370983
110Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.59466743
111Platelet activation_Homo sapiens_hsa046110.57359357
112Endocytosis_Homo sapiens_hsa041440.54229473
113Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.52453597
114Small cell lung cancer_Homo sapiens_hsa052220.50492325
115Pentose and glucuronate interconversions_Homo sapiens_hsa000400.50386169
116Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.50062041
117Central carbon metabolism in cancer_Homo sapiens_hsa052300.49458511
118Phenylalanine metabolism_Homo sapiens_hsa003600.49309303
119Apoptosis_Homo sapiens_hsa042100.47277482
120Dilated cardiomyopathy_Homo sapiens_hsa054140.46166304
121Bladder cancer_Homo sapiens_hsa052190.43850538
122Pathways in cancer_Homo sapiens_hsa052000.43676535
123Acute myeloid leukemia_Homo sapiens_hsa052210.42346858
124Primary immunodeficiency_Homo sapiens_hsa053400.41298836
125Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.40213900
126Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.40143848
127Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.39960390
128Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.39511956
129MicroRNAs in cancer_Homo sapiens_hsa052060.39179975
130Shigellosis_Homo sapiens_hsa051310.39018966
131Galactose metabolism_Homo sapiens_hsa000520.38423189
132Primary bile acid biosynthesis_Homo sapiens_hsa001200.38202851
133Chronic myeloid leukemia_Homo sapiens_hsa052200.36965079
134Measles_Homo sapiens_hsa051620.36372793
135Transcriptional misregulation in cancer_Homo sapiens_hsa052020.36143859
136Lysine degradation_Homo sapiens_hsa003100.35739386
137N-Glycan biosynthesis_Homo sapiens_hsa005100.34525539
138Fatty acid degradation_Homo sapiens_hsa000710.32764437
139Vitamin digestion and absorption_Homo sapiens_hsa049770.32070522
140Fat digestion and absorption_Homo sapiens_hsa049750.32059963
141Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.29689257
142Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.29508208
143Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.28924980
144Hepatitis B_Homo sapiens_hsa051610.28868184
145Metabolic pathways_Homo sapiens_hsa011000.28366863
146Arginine and proline metabolism_Homo sapiens_hsa003300.27815720
147Influenza A_Homo sapiens_hsa051640.25307214
148Renin-angiotensin system_Homo sapiens_hsa046140.24616318
149NF-kappa B signaling pathway_Homo sapiens_hsa040640.24521016
150Arginine biosynthesis_Homo sapiens_hsa002200.23471527
151Caffeine metabolism_Homo sapiens_hsa002320.19185538
152HIF-1 signaling pathway_Homo sapiens_hsa040660.19181982
153Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.17143095
154B cell receptor signaling pathway_Homo sapiens_hsa046620.17113791
155Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.15141512
156Propanoate metabolism_Homo sapiens_hsa006400.14189221
157mTOR signaling pathway_Homo sapiens_hsa041500.14065088
158RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.13430610
159Tryptophan metabolism_Homo sapiens_hsa003800.13391601
160Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.13373428
161Viral myocarditis_Homo sapiens_hsa054160.13153055

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