NOP10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nop10p. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)7.16656049
2chaperone-mediated protein transport (GO:0072321)6.32797926
3DNA deamination (GO:0045006)6.24972763
4viral transcription (GO:0019083)6.19718187
5translational termination (GO:0006415)6.02858085
6ribosomal small subunit biogenesis (GO:0042274)5.80802466
7maturation of SSU-rRNA (GO:0030490)5.70799981
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.45372714
9cotranslational protein targeting to membrane (GO:0006613)5.36069147
10translational elongation (GO:0006414)5.32285521
11protein targeting to ER (GO:0045047)5.31803606
12ribosomal large subunit biogenesis (GO:0042273)5.19528246
13protein neddylation (GO:0045116)5.06716982
14protein localization to endoplasmic reticulum (GO:0070972)5.06249500
15establishment of protein localization to endoplasmic reticulum (GO:0072599)5.04157888
16translational initiation (GO:0006413)4.74316057
17cellular protein complex disassembly (GO:0043624)4.74034252
18viral life cycle (GO:0019058)4.70980071
19nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.66501996
20telomere maintenance via semi-conservative replication (GO:0032201)4.60926333
21proteasome assembly (GO:0043248)4.60670923
22mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.52973102
23DNA strand elongation involved in DNA replication (GO:0006271)4.43823484
24establishment of integrated proviral latency (GO:0075713)4.36893426
25ribonucleoprotein complex biogenesis (GO:0022613)4.34743542
26translation (GO:0006412)4.25780230
27DNA strand elongation (GO:0022616)4.24056098
28deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.16600961
29ATP synthesis coupled proton transport (GO:0015986)4.14431710
30energy coupled proton transport, down electrochemical gradient (GO:0015985)4.14431710
31protein complex disassembly (GO:0043241)4.11884619
32telomere maintenance via recombination (GO:0000722)3.99579446
33hydrogen ion transmembrane transport (GO:1902600)3.95742376
34regulation of mitochondrial translation (GO:0070129)3.95014533
35macromolecular complex disassembly (GO:0032984)3.94281034
36DNA replication initiation (GO:0006270)3.90727665
37transcription elongation from RNA polymerase III promoter (GO:0006385)3.87202587
38termination of RNA polymerase III transcription (GO:0006386)3.87202587
39cellular component biogenesis (GO:0044085)3.86635763
40positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.84206042
41ATP biosynthetic process (GO:0006754)3.82730161
42signal transduction involved in cell cycle checkpoint (GO:0072395)3.82119122
43formation of translation preinitiation complex (GO:0001731)3.82027284
44* rRNA processing (GO:0006364)3.79546036
45inner mitochondrial membrane organization (GO:0007007)3.77540614
46spliceosomal snRNP assembly (GO:0000387)3.75398866
47protein localization to mitochondrion (GO:0070585)3.74979836
48CENP-A containing nucleosome assembly (GO:0034080)3.74555262
49positive regulation of ligase activity (GO:0051351)3.70460955
50chromatin remodeling at centromere (GO:0031055)3.69159436
51rRNA modification (GO:0000154)3.68165957
52nuclear-transcribed mRNA catabolic process (GO:0000956)3.67047952
53respiratory chain complex IV assembly (GO:0008535)3.65886543
54* rRNA metabolic process (GO:0016072)3.64323639
55purine nucleoside triphosphate biosynthetic process (GO:0009145)3.62518203
56exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.62241714
57nucleobase biosynthetic process (GO:0046112)3.61845457
58mitotic recombination (GO:0006312)3.60245718
59purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.60126204
60negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.58104311
61* pseudouridine synthesis (GO:0001522)3.57100757
62protein complex biogenesis (GO:0070271)3.56753517
63DNA replication checkpoint (GO:0000076)3.56073464
64nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.53145287
65establishment of protein localization to mitochondrial membrane (GO:0090151)3.52746226
66purine nucleobase biosynthetic process (GO:0009113)3.51549559
67telomere maintenance via telomere lengthening (GO:0010833)3.51539540
68establishment of viral latency (GO:0019043)3.51257028
69ribosome biogenesis (GO:0042254)3.50414474
70mRNA catabolic process (GO:0006402)3.50361178
71mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.48196959
72mitochondrial respiratory chain complex I assembly (GO:0032981)3.48196959
73NADH dehydrogenase complex assembly (GO:0010257)3.48196959
74proton transport (GO:0015992)3.46353574
75regulation of ubiquitin-protein transferase activity (GO:0051438)3.46016750
76nucleotide-excision repair, DNA gap filling (GO:0006297)3.44883478
77antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.44597916
78mitochondrial respiratory chain complex assembly (GO:0033108)3.44472265
79protein targeting to membrane (GO:0006612)3.42510277
80transcription-coupled nucleotide-excision repair (GO:0006283)3.40901502
81spliceosomal complex assembly (GO:0000245)3.38673387
82hydrogen transport (GO:0006818)3.38404311
83rRNA methylation (GO:0031167)3.38321919
84regulation of ligase activity (GO:0051340)3.36111550
85GTP biosynthetic process (GO:0006183)3.35688304
86mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.32971995
87RNA catabolic process (GO:0006401)3.31784240
88respiratory electron transport chain (GO:0022904)3.31562337
89positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.30950962
90mitochondrial transport (GO:0006839)3.29710486
91regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.29161405
92regulation of cellular amino acid metabolic process (GO:0006521)3.26973211
93negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.26679657
94negative regulation of ligase activity (GO:0051352)3.26679657
95maturation of 5.8S rRNA (GO:0000460)3.25137671
96ribonucleoside triphosphate biosynthetic process (GO:0009201)3.25045239
97DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.24392624
98protein targeting to mitochondrion (GO:0006626)3.24151853
99electron transport chain (GO:0022900)3.23683480
100anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.21837949
101tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.21233322
102RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.21233322
103intracellular protein transmembrane import (GO:0044743)3.21110716
1047-methylguanosine mRNA capping (GO:0006370)3.20618948
105pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.20302422
106intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.19997179
107signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.19997179
108antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.19878116
109regulation of cellular amine metabolic process (GO:0033238)3.18463157
110signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.17805663
111signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.17805663
112signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.17805663
1137-methylguanosine RNA capping (GO:0009452)3.17264648
114RNA capping (GO:0036260)3.17264648
115deoxyribose phosphate biosynthetic process (GO:0046385)3.15932583
1162-deoxyribonucleotide biosynthetic process (GO:0009265)3.15932583
117UTP biosynthetic process (GO:0006228)3.15734113
118guanosine-containing compound biosynthetic process (GO:1901070)3.14610544
119cytochrome complex assembly (GO:0017004)3.13985466
120oxidative phosphorylation (GO:0006119)3.13691481
121DNA unwinding involved in DNA replication (GO:0006268)3.13082470
122positive regulation of cell cycle arrest (GO:0071158)3.12990464
123establishment of protein localization to mitochondrion (GO:0072655)3.11801154
124negative regulation of protein ubiquitination (GO:0031397)3.10483211
125signal transduction involved in DNA damage checkpoint (GO:0072422)3.10343533
126signal transduction involved in DNA integrity checkpoint (GO:0072401)3.10343533
127water-soluble vitamin biosynthetic process (GO:0042364)3.08061950

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.47266982
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.67094962
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.26590103
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.11892929
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.87383059
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.85106213
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.64253860
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.42096158
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.23502807
10MYC_18358816_ChIP-ChIP_MESCs_Mouse3.22128386
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.21540766
12SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.16011780
13CREB1_15753290_ChIP-ChIP_HEK293T_Human3.03670937
14MYC_19079543_ChIP-ChIP_MESCs_Mouse3.02753378
15E2F4_17652178_ChIP-ChIP_JURKAT_Human2.97312639
16MYC_19030024_ChIP-ChIP_MESCs_Mouse2.94366056
17ELF1_17652178_ChIP-ChIP_JURKAT_Human2.88815576
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.71708335
19* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.66666815
20* VDR_23849224_ChIP-Seq_CD4+_Human2.63769002
21XRN2_22483619_ChIP-Seq_HELA_Human2.54752919
22CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.49172226
23FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.48340595
24DCP1A_22483619_ChIP-Seq_HELA_Human2.37433844
25* FOXP3_21729870_ChIP-Seq_TREG_Human2.28772784
26E2F1_18555785_ChIP-Seq_MESCs_Mouse2.27307585
27FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.24950181
28NELFA_20434984_ChIP-Seq_ESCs_Mouse2.21016905
29THAP11_20581084_ChIP-Seq_MESCs_Mouse2.18687419
30SRF_21415370_ChIP-Seq_HL-1_Mouse2.14029560
31* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.12164233
32E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.12125324
33TTF2_22483619_ChIP-Seq_HELA_Human2.11503683
34GABP_19822575_ChIP-Seq_HepG2_Human1.99430742
35ELK1_19687146_ChIP-ChIP_HELA_Human1.99346006
36YY1_21170310_ChIP-Seq_MESCs_Mouse1.96914678
37FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.94296955
38* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.93028705
39FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.81536208
40HOXB4_20404135_ChIP-ChIP_EML_Mouse1.81461744
41BP1_19119308_ChIP-ChIP_Hs578T_Human1.81067049
42PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.80172851
43FOXM1_23109430_ChIP-Seq_U2OS_Human1.76310110
44ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.73569836
45PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.71720700
46MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.69664371
47POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.63055716
48MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.61689232
49MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.60876522
50ERG_20887958_ChIP-Seq_HPC-7_Mouse1.60507251
51MYCN_18555785_ChIP-Seq_MESCs_Mouse1.58313619
52E2F1_21310950_ChIP-Seq_MCF-7_Human1.53181317
53YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.50364911
54NANOG_18555785_ChIP-Seq_MESCs_Mouse1.47617779
55NOTCH1_21737748_ChIP-Seq_TLL_Human1.47011880
56* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.46163159
57SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.46019541
58CIITA_25753668_ChIP-Seq_RAJI_Human1.45207096
59ZFX_18555785_ChIP-Seq_MESCs_Mouse1.45130589
60AR_21909140_ChIP-Seq_LNCAP_Human1.32804272
61MYC_18940864_ChIP-ChIP_HL60_Human1.32000958
62ELK1_22589737_ChIP-Seq_MCF10A_Human1.24944215
63SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.24302723
64PADI4_21655091_ChIP-ChIP_MCF-7_Human1.20813734
65POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.20027084
66BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.19840672
67KDM5A_27292631_Chip-Seq_BREAST_Human1.19348772
68RBPJ_22232070_ChIP-Seq_NCS_Mouse1.18376603
69CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.10084635
70GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.07508941
71NANOG_16153702_ChIP-ChIP_HESCs_Human1.07498119
72* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.07188331
73SPI1_23547873_ChIP-Seq_NB4_Human1.07074481
74CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.04697532
75CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.03136029
76IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.01406453
77E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.98422555
78KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.98038668
79ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.96954252
80CTCF_18555785_ChIP-Seq_MESCs_Mouse0.96840790
81STAT3_1855785_ChIP-Seq_MESCs_Mouse0.96669468
82SOX2_16153702_ChIP-ChIP_HESCs_Human0.95585304
83HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.94599104
84HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.89925431
85CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.88176840
86EWS_26573619_Chip-Seq_HEK293_Human0.87938637
87HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.87929678
88ELF5_23300383_ChIP-Seq_T47D_Human0.85033476
89SOX17_20123909_ChIP-Seq_XEN_Mouse0.84649911
90ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.84621170
91TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.84315660
92POU5F1_16153702_ChIP-ChIP_HESCs_Human0.83907162
93DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.83755667
94VDR_22108803_ChIP-Seq_LS180_Human0.83603037
95NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.83197402
96SOX2_18555785_ChIP-Seq_MESCs_Mouse0.82721405
97* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82097021
98IRF1_19129219_ChIP-ChIP_H3396_Human0.82031060
99DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.80521670
100KLF4_18555785_ChIP-Seq_MESCs_Mouse0.80397849
101SRY_22984422_ChIP-ChIP_TESTIS_Rat0.80328851
102TFEB_21752829_ChIP-Seq_HELA_Human0.80258991
103ZNF274_21170338_ChIP-Seq_K562_Hela0.77815774
104SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.77163653
105CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.76674468
106RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.75756406
107POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.74369807
108TP53_22573176_ChIP-Seq_HFKS_Human0.73160760
109FLI1_27457419_Chip-Seq_LIVER_Mouse0.71629325
110SOX2_18692474_ChIP-Seq_MEFs_Mouse0.71362941
111HTT_18923047_ChIP-ChIP_STHdh_Human0.71328811
112MYC_22102868_ChIP-Seq_BL_Human0.71011772
113* GATA1_22383799_ChIP-Seq_G1ME_Mouse0.68448984
114STAT4_19710469_ChIP-ChIP_TH1__Mouse0.67974708
115VDR_21846776_ChIP-Seq_THP-1_Human0.67231049
116EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.66777094
117ERG_20517297_ChIP-Seq_VCAP_Human0.66234720
118OCT4_18692474_ChIP-Seq_MEFs_Mouse0.64811506
119ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.64379313

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.30028157
2MP0009379_abnormal_foot_pigmentation4.85749995
3MP0004957_abnormal_blastocyst_morpholog4.17859047
4MP0010094_abnormal_chromosome_stability3.95243278
5MP0008057_abnormal_DNA_replication3.70659821
6MP0003077_abnormal_cell_cycle3.36819689
7MP0008058_abnormal_DNA_repair3.30463996
8MP0003111_abnormal_nucleus_morphology3.28968836
9MP0002396_abnormal_hematopoietic_system2.86580295
10MP0003941_abnormal_skin_development2.66692037
11MP0008932_abnormal_embryonic_tissue2.52941264
12MP0008007_abnormal_cellular_replicative2.50918818
13MP0003186_abnormal_redox_activity2.49752013
14MP0003806_abnormal_nucleotide_metabolis2.47278690
15MP0006036_abnormal_mitochondrial_physio2.24003416
16MP0003786_premature_aging2.11719127
17MP0005084_abnormal_gallbladder_morpholo2.09030199
18MP0002837_dystrophic_cardiac_calcinosis2.07023879
19MP0003011_delayed_dark_adaptation2.03585269
20MP0000490_abnormal_crypts_of2.02077375
21MP0004147_increased_porphyrin_level1.99121756
22MP0006072_abnormal_retinal_apoptosis1.95791939
23MP0002132_abnormal_respiratory_system1.93125101
24MP0003123_paternal_imprinting1.90615637
25MP0009333_abnormal_splenocyte_physiolog1.77131773
26MP0003136_yellow_coat_color1.71771294
27MP0003763_abnormal_thymus_physiology1.70835964
28MP0006035_abnormal_mitochondrial_morpho1.70656267
29MP0003718_maternal_effect1.68723577
30MP0001853_heart_inflammation1.67145241
31MP0005075_abnormal_melanosome_morpholog1.61967346
32MP0001293_anophthalmia1.60526062
33MP0002254_reproductive_system_inflammat1.58926935
34MP0001545_abnormal_hematopoietic_system1.57585118
35MP0005397_hematopoietic_system_phenotyp1.57585118
36MP0008877_abnormal_DNA_methylation1.56015544
37MP0001986_abnormal_taste_sensitivity1.53857760
38MP0005174_abnormal_tail_pigmentation1.52805692
39MP0000350_abnormal_cell_proliferation1.46021920
40MP0001835_abnormal_antigen_presentation1.43407531
41MP0009697_abnormal_copulation1.42044530
42MP0006292_abnormal_olfactory_placode1.41818401
43MP0001529_abnormal_vocalization1.41591894
44MP0002736_abnormal_nociception_after1.40227971
45MP0000313_abnormal_cell_death1.40100169
46MP0003315_abnormal_perineum_morphology1.38988664
47MP0008995_early_reproductive_senescence1.37547859
48MP0005671_abnormal_response_to1.36334527
49MP0010030_abnormal_orbit_morphology1.34471224
50MP0001730_embryonic_growth_arrest1.33311404
51MP0002019_abnormal_tumor_incidence1.31632817
52MP0002398_abnormal_bone_marrow1.26285509
53MP0001764_abnormal_homeostasis1.26241164
54MP0002095_abnormal_skin_pigmentation1.24772469
55MP0008875_abnormal_xenobiotic_pharmacok1.22996230
56MP0003195_calcinosis1.22949991
57MP0000358_abnormal_cell_content/1.22706951
58MP0002722_abnormal_immune_system1.22431395
59MP0003724_increased_susceptibility_to1.22082814
60MP0000689_abnormal_spleen_morphology1.21277128
61MP0009785_altered_susceptibility_to1.21199311
62MP0006054_spinal_hemorrhage1.18426403
63MP0004808_abnormal_hematopoietic_stem1.18082832
64MP0002148_abnormal_hypersensitivity_rea1.16332261
65MP0002160_abnormal_reproductive_system1.14348839
66MP0002102_abnormal_ear_morphology1.13538342
67MP0001188_hyperpigmentation1.09585540
68MP0005395_other_phenotype1.08558886
69MP0000703_abnormal_thymus_morphology1.07993405
70MP0002429_abnormal_blood_cell1.07577961
71MP0004142_abnormal_muscle_tone1.04871306
72MP0005410_abnormal_fertilization1.03526666
73MP0003656_abnormal_erythrocyte_physiolo1.03266260
74MP0000858_altered_metastatic_potential1.02243532
75MP0002638_abnormal_pupillary_reflex1.01450587
76MP0002163_abnormal_gland_morphology1.01294717
77MP0005025_abnormal_response_to1.00923438
78MP0006082_CNS_inflammation1.00303589
79MP0000372_irregular_coat_pigmentation0.98731142
80MP0000716_abnormal_immune_system0.98644430
81MP0005332_abnormal_amino_acid0.96708933
82MP0001697_abnormal_embryo_size0.94369472
83MP0002080_prenatal_lethality0.94014084
84MP0002210_abnormal_sex_determination0.93335009
85MP0002420_abnormal_adaptive_immunity0.91983746
86MP0002938_white_spotting0.90414580
87MP0001819_abnormal_immune_cell0.90072405
88MP0001727_abnormal_embryo_implantation0.89786252
89MP0001905_abnormal_dopamine_level0.89094847
90MP0005266_abnormal_metabolism0.88530687
91MP0002090_abnormal_vision0.88080844
92MP0001984_abnormal_olfaction0.86369461
93MP0005389_reproductive_system_phenotype0.86205231
94MP0008872_abnormal_physiological_respon0.84846098
95MP0001881_abnormal_mammary_gland0.84813214
96MP0002277_abnormal_respiratory_mucosa0.84761413
97MP0001145_abnormal_male_reproductive0.84309681
98MP0000015_abnormal_ear_pigmentation0.83942829
99MP0004019_abnormal_vitamin_homeostasis0.83565545
100MP0002139_abnormal_hepatobiliary_system0.83437627
101MP0001800_abnormal_humoral_immune0.83262866
102MP0005253_abnormal_eye_physiology0.82991515
103MP0001485_abnormal_pinna_reflex0.82925667
104MP0002723_abnormal_immune_serum0.82341370
105MP0005499_abnormal_olfactory_system0.81496409
106MP0005394_taste/olfaction_phenotype0.81496409
107MP0005000_abnormal_immune_tolerance0.81325949
108MP0002405_respiratory_system_inflammati0.80353651
109MP0002452_abnormal_antigen_presenting0.79695885
110MP0002006_tumorigenesis0.78525083
111MP0001929_abnormal_gametogenesis0.77733059
112MP0003567_abnormal_fetal_cardiomyocyte0.76942233
113MP0010386_abnormal_urinary_bladder0.76542280
114MP0005379_endocrine/exocrine_gland_phen0.75024041
115MP0005636_abnormal_mineral_homeostasis0.73732382
116MP0008789_abnormal_olfactory_epithelium0.73617255
117MP0002876_abnormal_thyroid_physiology0.73365424
118MP0000653_abnormal_sex_gland0.73223161
119MP0008873_increased_physiological_sensi0.71985834
120MP0000343_altered_response_to0.71782726
121MP0005319_abnormal_enzyme/_coenzyme0.71513677
122MP0001119_abnormal_female_reproductive0.70567282
123MP0005408_hypopigmentation0.70279244
124MP0002166_altered_tumor_susceptibility0.70145533
125MP0010155_abnormal_intestine_physiology0.69512074
126MP0005380_embryogenesis_phenotype0.68129821
127MP0001672_abnormal_embryogenesis/_devel0.68129821
128MP0003866_abnormal_defecation0.67513173
129MP0001663_abnormal_digestive_system0.65020825
130MP0005409_darkened_coat_color0.64168461
131MP0003436_decreased_susceptibility_to0.63848353
132MP0001873_stomach_inflammation0.63758788
133MP0000685_abnormal_immune_system0.62152968
134MP0001919_abnormal_reproductive_system0.61469415
135MP0005551_abnormal_eye_electrophysiolog0.59947094
136MP0004215_abnormal_myocardial_fiber0.59828045
137MP0005085_abnormal_gallbladder_physiolo0.54849602
138MP0001968_abnormal_touch/_nociception0.54460717
139MP0001542_abnormal_bone_strength0.54028966
140MP0000631_abnormal_neuroendocrine_gland0.54007681
141MP0002751_abnormal_autonomic_nervous0.53434639
142MP0008469_abnormal_protein_level0.53366136
143MP0009765_abnormal_xenobiotic_induced0.51980504

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)6.74480965
2Abnormal number of erythroid precursors (HP:0012131)6.47925750
3Reticulocytopenia (HP:0001896)5.61476875
4Mitochondrial inheritance (HP:0001427)4.88914807
5Hepatocellular necrosis (HP:0001404)4.76413347
6Acute necrotizing encephalopathy (HP:0006965)4.74885913
7Abnormal mitochondria in muscle tissue (HP:0008316)4.47080691
8Increased CSF lactate (HP:0002490)4.43203108
9Increased hepatocellular lipid droplets (HP:0006565)4.42792579
10Decreased activity of mitochondrial respiratory chain (HP:0008972)4.33330017
11Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.33330017
12Macrocytic anemia (HP:0001972)4.31831488
13Hepatic necrosis (HP:0002605)4.26411477
14Pallor (HP:0000980)4.07728550
15Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.99997643
16Acute encephalopathy (HP:0006846)3.94316102
17Lipid accumulation in hepatocytes (HP:0006561)3.92951923
18Progressive macrocephaly (HP:0004481)3.83443425
19Birth length less than 3rd percentile (HP:0003561)3.76704060
20Increased serum lactate (HP:0002151)3.71200295
21Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.67554096
22Renal Fanconi syndrome (HP:0001994)3.54609134
23Increased intramyocellular lipid droplets (HP:0012240)3.53078317
24Exertional dyspnea (HP:0002875)3.49381593
25Congenital, generalized hypertrichosis (HP:0004540)3.37965175
263-Methylglutaconic aciduria (HP:0003535)3.30128846
27Aplasia/Hypoplasia of the sacrum (HP:0008517)3.26481463
28Type I transferrin isoform profile (HP:0003642)3.25130213
29Exercise intolerance (HP:0003546)3.12454905
30Lactic acidosis (HP:0003128)3.09338814
31Methylmalonic acidemia (HP:0002912)2.98884211
32Increased muscle lipid content (HP:0009058)2.98765043
33Respiratory difficulties (HP:0002880)2.95821994
34Respiratory failure (HP:0002878)2.91396615
35Microvesicular hepatic steatosis (HP:0001414)2.84156203
3611 pairs of ribs (HP:0000878)2.83127787
37Abnormality of the heme biosynthetic pathway (HP:0010472)2.81040144
38Generalized aminoaciduria (HP:0002909)2.79806523
39Methylmalonic aciduria (HP:0012120)2.74039729
40Thrombocytosis (HP:0001894)2.73478627
41Cerebral edema (HP:0002181)2.67784749
42Abnormality of methionine metabolism (HP:0010901)2.66090529
43Amniotic constriction ring (HP:0009775)2.65360985
44Abnormality of placental membranes (HP:0011409)2.65360985
45Chromsome breakage (HP:0040012)2.62648220
46Colon cancer (HP:0003003)2.60434560
47Abnormality of the preputium (HP:0100587)2.54986565
48Microretrognathia (HP:0000308)2.52962427
49Breast hypoplasia (HP:0003187)2.49106410
50Reduced antithrombin III activity (HP:0001976)2.45501979
51Absent thumb (HP:0009777)2.45282440
52Increased serum pyruvate (HP:0003542)2.45014132
53Abnormality of glycolysis (HP:0004366)2.45014132
54* Aplastic anemia (HP:0001915)2.41345553
55Septo-optic dysplasia (HP:0100842)2.37523485
56Abnormality of aspartate family amino acid metabolism (HP:0010899)2.32718086
57Chromosomal breakage induced by crosslinking agents (HP:0003221)2.31441728
58Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.31429816
59Abnormal protein N-linked glycosylation (HP:0012347)2.30934454
60Abnormal protein glycosylation (HP:0012346)2.30934454
61Abnormal glycosylation (HP:0012345)2.30934454
62Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.30934454
63* Pancytopenia (HP:0001876)2.29528465
64IgM deficiency (HP:0002850)2.26408676
65Cerebral hypomyelination (HP:0006808)2.25116421
66Abnormality of renal resorption (HP:0011038)2.20673127
67CNS demyelination (HP:0007305)2.20384566
68Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.20354104
69Abnormality of alanine metabolism (HP:0010916)2.20354104
70Hyperalaninemia (HP:0003348)2.20354104
71Abnormality of chromosome stability (HP:0003220)2.20065220
72X-linked dominant inheritance (HP:0001423)2.19895988
73Optic disc pallor (HP:0000543)2.17597651
74Emotional lability (HP:0000712)2.15385801
75Meckel diverticulum (HP:0002245)2.14243818
76Abnormality of the anterior horn cell (HP:0006802)2.10345129
77Degeneration of anterior horn cells (HP:0002398)2.10345129
78Muscle fiber atrophy (HP:0100295)2.07948834
79Carpal bone hypoplasia (HP:0001498)2.07882643
80Myelodysplasia (HP:0002863)2.07457319
81Abnormality of the ileum (HP:0001549)2.07159397
82Type 2 muscle fiber atrophy (HP:0003554)2.04780509
83Abnormality of reticulocytes (HP:0004312)2.03899258
84Megaloblastic anemia (HP:0001889)2.02841181
85Leukodystrophy (HP:0002415)1.99260412
86* Rough bone trabeculation (HP:0100670)1.99132314
87Nausea (HP:0002018)1.98452732
88Abnormal hemoglobin (HP:0011902)1.98425738
89Abnormal spermatogenesis (HP:0008669)1.97577501
90Trismus (HP:0000211)1.95854999
91Dicarboxylic aciduria (HP:0003215)1.94214262
92Abnormality of dicarboxylic acid metabolism (HP:0010995)1.94214262
93Petechiae (HP:0000967)1.93880959
94Hyperphosphaturia (HP:0003109)1.91853030
95Triphalangeal thumb (HP:0001199)1.91469889
96Abnormality of serum amino acid levels (HP:0003112)1.91388435
97Absent septum pellucidum (HP:0001331)1.88282526
98Poor head control (HP:0002421)1.86760406
99Cleft eyelid (HP:0000625)1.86609527
100Aplasia/Hypoplasia of the uvula (HP:0010293)1.85832766
101Secondary amenorrhea (HP:0000869)1.85744566
102Pancreatic cysts (HP:0001737)1.82770656
103Multiple enchondromatosis (HP:0005701)1.81887992
104Abnormality of urine glucose concentration (HP:0011016)1.81366559
105Glycosuria (HP:0003076)1.81366559
106Abnormality of the labia minora (HP:0012880)1.80848420
107Severe visual impairment (HP:0001141)1.79489759
108Abnormal pupillary function (HP:0007686)1.79010204
109Horseshoe kidney (HP:0000085)1.77719782
110Abnormal urine phosphate concentration (HP:0012599)1.76927735
111Congenital ichthyosiform erythroderma (HP:0007431)1.76791512
112Pancreatic fibrosis (HP:0100732)1.75990793
113* Bone marrow hypocellularity (HP:0005528)1.75924337
114Gliosis (HP:0002171)1.75041871
115Homocystinuria (HP:0002156)1.74963526
116Abnormality of homocysteine metabolism (HP:0010919)1.74963526
117Abnormality of aromatic amino acid family metabolism (HP:0004338)1.74582593
118Blindness (HP:0000618)1.74582580
119Hypoplasia of the radius (HP:0002984)1.74436692
120Patellar aplasia (HP:0006443)1.73480146
121Selective tooth agenesis (HP:0001592)1.72857174
122Renal tubular dysfunction (HP:0000124)1.72639068
123Progressive muscle weakness (HP:0003323)1.71644711
124Absent rod-and cone-mediated responses on ERG (HP:0007688)1.71599385
125Abnormality of vitamin B metabolism (HP:0004340)1.71122945
126Hypoglycemic coma (HP:0001325)1.70424275
127Hyperglycinemia (HP:0002154)1.69907017
128Hypoplasia of the pons (HP:0012110)1.69680188
129Depressed nasal ridge (HP:0000457)1.69483501
130Abnormality of the vitamin B12 metabolism (HP:0004341)1.69474474
131* Premature graying of hair (HP:0002216)1.68598178
132Abnormality of the pons (HP:0007361)1.68167969
133Aplasia/hypoplasia of the uterus (HP:0008684)1.64976864
134Vomiting (HP:0002013)1.62769588
135Lethargy (HP:0001254)1.62078464
136Aplasia/Hypoplasia of the patella (HP:0006498)1.61526372
137Parakeratosis (HP:0001036)1.61407986
138Abnormality of the septum pellucidum (HP:0007375)1.60133102
139* Sparse eyelashes (HP:0000653)1.59722992
140Testicular atrophy (HP:0000029)1.59016760

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK26.01835043
2STK164.22822093
3NME24.17559781
4BUB13.60997760
5WEE13.56547014
6EIF2AK13.40714693
7VRK13.06923767
8CDC72.99521078
9PIM22.54554686
10SRPK12.44751444
11EIF2AK32.44200840
12TLK12.41724766
13ACVR1B2.14083210
14NUAK12.05222587
15NME11.94048155
16MAP3K121.91108014
17TAF11.87836329
18PLK41.75367698
19BRSK21.74368124
20TSSK61.74327420
21PBK1.66843142
22TESK21.64825467
23PLK11.43036412
24MKNK11.40147839
25NEK11.36864505
26AURKB1.32683073
27IRAK31.30587432
28PDK21.26948857
29MKNK21.25776511
30CDK71.25543978
31CDK81.24681503
32CCNB11.24290876
33WNK31.24029641
34TEC1.23747359
35BRAF1.23436028
36KDR1.22810770
37RPS6KB21.19739555
38DYRK31.17510082
39ATR1.15987926
40MAP3K111.13869801
41SCYL21.12359851
42BCKDK1.12072743
43AURKA1.07801361
44ZAK1.07674159
45IRAK41.07633549
46CDK191.06750151
47NEK21.05994080
48TTK1.02316879
49EIF2AK20.98877331
50MST40.94994501
51MYLK0.94492695
52BRSK10.93455412
53MAP4K20.87270398
54PLK30.85037372
55CSNK2A10.84271349
56TESK10.83955667
57GRK10.83670546
58TRIM280.82699463
59CSNK2A20.81831794
60PASK0.81339926
61TGFBR10.80953680
62FLT30.80851977
63RPS6KA40.78042990
64DAPK30.76464105
65TNIK0.75934446
66MAP4K10.74902824
67ABL20.73967645
68OXSR10.73721111
69MUSK0.71428328
70CHEK20.71069729
71BTK0.69916180
72PIM10.69683600
73INSRR0.65527831
74CSNK1G30.65240337
75BMPR1B0.65151119
76CSNK1G10.64369624
77DAPK10.60709084
78TXK0.60548709
79MAP3K80.60199021
80TIE10.59124094
81LRRK20.58847854
82KIT0.58328498
83STK40.56292791
84ADRBK20.54138335
85RPS6KA50.52691875
86BLK0.52432429
87ARAF0.52131902
88PAK40.52058853
89CHEK10.51196553
90CSNK1G20.49986476
91ATM0.46831852
92ILK0.46802955
93LIMK10.46751981
94CDK40.44813895
95LYN0.44230921
96DYRK20.42599857
97IKBKB0.42267121
98MAP2K60.41003491
99YES10.40628360
100SYK0.40448314
101TAOK20.40422016
102PAK10.40213321
103GRK70.40193985
104MAPKAPK30.39207597
105MAP2K20.38511068
106ALK0.38303328
107PRKG20.37272292
108CDK20.35613414
109MAP2K30.35376485
110STK240.35328010
111PRKCI0.35056238
112PLK20.34984192
113ZAP700.33633494
114PIK3CG0.33334196
115MAPKAPK50.32057156
116CSNK1A1L0.31660978
117ERBB40.29744819
118MAPK40.29191035
119RPS6KA60.28095557
120MATK0.27491208
121RAF10.27130485
122PRKCG0.26974797
123NLK0.26720744
124CSNK1A10.25027530
125MAP2K70.21404296
126STK30.21291710
127CSNK1E0.20745713
128STK390.20278313
129MAP3K50.20187965
130WNK40.19507012
131GRK50.18931559

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.59419546
2DNA replication_Homo sapiens_hsa030304.45065117
3Proteasome_Homo sapiens_hsa030504.02697944
4RNA polymerase_Homo sapiens_hsa030203.64197584
5Mismatch repair_Homo sapiens_hsa034303.63785201
6Oxidative phosphorylation_Homo sapiens_hsa001903.06048152
7* Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.88559880
8Parkinsons disease_Homo sapiens_hsa050122.86239499
9Pyrimidine metabolism_Homo sapiens_hsa002402.85491616
10Homologous recombination_Homo sapiens_hsa034402.83872487
11Spliceosome_Homo sapiens_hsa030402.83691981
12Base excision repair_Homo sapiens_hsa034102.56200052
13Nucleotide excision repair_Homo sapiens_hsa034202.53831452
14Protein export_Homo sapiens_hsa030602.25390583
15Huntingtons disease_Homo sapiens_hsa050162.23970694
16RNA transport_Homo sapiens_hsa030132.08119982
17One carbon pool by folate_Homo sapiens_hsa006701.98776218
18Fanconi anemia pathway_Homo sapiens_hsa034601.85363361
19Alzheimers disease_Homo sapiens_hsa050101.79650793
20RNA degradation_Homo sapiens_hsa030181.75220496
21Non-homologous end-joining_Homo sapiens_hsa034501.70309343
22Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.68690142
23Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.67280657
24Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.63674509
25Purine metabolism_Homo sapiens_hsa002301.60033149
26Basal transcription factors_Homo sapiens_hsa030221.60016728
27Cell cycle_Homo sapiens_hsa041101.55495868
28Folate biosynthesis_Homo sapiens_hsa007901.34340302
29Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.22538620
30Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.15299844
31Sulfur relay system_Homo sapiens_hsa041221.04593310
32Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.02776132
33Sulfur metabolism_Homo sapiens_hsa009200.95215798
34Collecting duct acid secretion_Homo sapiens_hsa049660.93673483
35Propanoate metabolism_Homo sapiens_hsa006400.90386224
36p53 signaling pathway_Homo sapiens_hsa041150.89432257
37Pentose phosphate pathway_Homo sapiens_hsa000300.89254089
38Cysteine and methionine metabolism_Homo sapiens_hsa002700.88894692
39Systemic lupus erythematosus_Homo sapiens_hsa053220.87200207
40Epstein-Barr virus infection_Homo sapiens_hsa051690.86250200
41Drug metabolism - other enzymes_Homo sapiens_hsa009830.80443951
42Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.78842408
43Glutathione metabolism_Homo sapiens_hsa004800.78550315
44Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.76405693
45Cardiac muscle contraction_Homo sapiens_hsa042600.76260320
46Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.72237013
47Cyanoamino acid metabolism_Homo sapiens_hsa004600.68242465
48N-Glycan biosynthesis_Homo sapiens_hsa005100.67145373
49Metabolic pathways_Homo sapiens_hsa011000.65008516
50mRNA surveillance pathway_Homo sapiens_hsa030150.64912406
51Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.63924305
52Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.62879633
53Vitamin digestion and absorption_Homo sapiens_hsa049770.60668961
54Rheumatoid arthritis_Homo sapiens_hsa053230.59654392
55Antigen processing and presentation_Homo sapiens_hsa046120.58875966
56Herpes simplex infection_Homo sapiens_hsa051680.56443147
57Primary immunodeficiency_Homo sapiens_hsa053400.56176436
58Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.52674366
59Steroid biosynthesis_Homo sapiens_hsa001000.51191125
60Biosynthesis of amino acids_Homo sapiens_hsa012300.50936106
61Vitamin B6 metabolism_Homo sapiens_hsa007500.49741310
62Caffeine metabolism_Homo sapiens_hsa002320.49658933
63Chemical carcinogenesis_Homo sapiens_hsa052040.49133288
64SNARE interactions in vesicular transport_Homo sapiens_hsa041300.47641663
65Carbon metabolism_Homo sapiens_hsa012000.46779584
66Legionellosis_Homo sapiens_hsa051340.45527681
67Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.40893660
68Arachidonic acid metabolism_Homo sapiens_hsa005900.40700967
69Tryptophan metabolism_Homo sapiens_hsa003800.38225906
70Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.35359605
71Butanoate metabolism_Homo sapiens_hsa006500.33979888
72Selenocompound metabolism_Homo sapiens_hsa004500.33752086
73Hematopoietic cell lineage_Homo sapiens_hsa046400.33404711
74Primary bile acid biosynthesis_Homo sapiens_hsa001200.32907725
75Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.32245172
76Galactose metabolism_Homo sapiens_hsa000520.32133272
77Thyroid cancer_Homo sapiens_hsa052160.31614984
78Allograft rejection_Homo sapiens_hsa053300.31055184
79Phototransduction_Homo sapiens_hsa047440.30894728
80Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.30414860
81Maturity onset diabetes of the young_Homo sapiens_hsa049500.30305015
822-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.29154439
83Mineral absorption_Homo sapiens_hsa049780.28713975
84Other glycan degradation_Homo sapiens_hsa005110.28577720
85Viral carcinogenesis_Homo sapiens_hsa052030.28422116
86Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.28113895
87Regulation of autophagy_Homo sapiens_hsa041400.28077288
88Pyruvate metabolism_Homo sapiens_hsa006200.27419998
89Nitrogen metabolism_Homo sapiens_hsa009100.27068935
90Retinol metabolism_Homo sapiens_hsa008300.25641768
91Intestinal immune network for IgA production_Homo sapiens_hsa046720.25611954
92Fructose and mannose metabolism_Homo sapiens_hsa000510.24630168
93Alcoholism_Homo sapiens_hsa050340.22709220
94Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.21601336
95Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.21261669
96Oocyte meiosis_Homo sapiens_hsa041140.20908640
97Measles_Homo sapiens_hsa051620.20825423
98Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.20351194
99RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.20141873
100Asthma_Homo sapiens_hsa053100.19560384
101Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.17930800
102Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.17832238
103Arginine and proline metabolism_Homo sapiens_hsa003300.17539639
104Graft-versus-host disease_Homo sapiens_hsa053320.16469911
105Fatty acid degradation_Homo sapiens_hsa000710.16139889
106Tyrosine metabolism_Homo sapiens_hsa003500.15976414
107beta-Alanine metabolism_Homo sapiens_hsa004100.15300811
108HTLV-I infection_Homo sapiens_hsa051660.15064997
109Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.14923815
110Phenylalanine metabolism_Homo sapiens_hsa003600.14227011
111Apoptosis_Homo sapiens_hsa042100.13982270
112Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.13599496
113Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.13327528
114Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.11252177
115Vibrio cholerae infection_Homo sapiens_hsa051100.10432819
116Peroxisome_Homo sapiens_hsa041460.09862918
117Renin-angiotensin system_Homo sapiens_hsa046140.09796947
118Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.09317127
119Pentose and glucuronate interconversions_Homo sapiens_hsa000400.09197361
120NF-kappa B signaling pathway_Homo sapiens_hsa040640.08475607
121Fatty acid elongation_Homo sapiens_hsa000620.08396551
122Type I diabetes mellitus_Homo sapiens_hsa049400.07324212
123Autoimmune thyroid disease_Homo sapiens_hsa053200.06261719
124Transcriptional misregulation in cancer_Homo sapiens_hsa052020.05959637
125Influenza A_Homo sapiens_hsa051640.05931508
126Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.05255910
127Linoleic acid metabolism_Homo sapiens_hsa005910.05032019
128NOD-like receptor signaling pathway_Homo sapiens_hsa046210.04963616

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »