NOL4L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)5.58606963
2acrosome reaction (GO:0007340)5.00603853
3sperm motility (GO:0030317)4.95787805
4fusion of sperm to egg plasma membrane (GO:0007342)4.84098407
5piRNA metabolic process (GO:0034587)4.80054719
6axonemal dynein complex assembly (GO:0070286)4.68534744
7behavioral response to nicotine (GO:0035095)4.64807712
8neuron cell-cell adhesion (GO:0007158)4.58251766
9epithelial cilium movement (GO:0003351)4.49156515
10multicellular organism reproduction (GO:0032504)4.49075207
11acrosome assembly (GO:0001675)4.36475710
12central nervous system myelination (GO:0022010)4.21897162
13axon ensheathment in central nervous system (GO:0032291)4.21897162
14sperm-egg recognition (GO:0035036)4.14184212
15regulation of cilium movement (GO:0003352)4.10082500
16cilium movement (GO:0003341)4.02834624
17male meiosis (GO:0007140)3.96400132
18neurotransmitter-gated ion channel clustering (GO:0072578)3.92020952
19plasma membrane fusion (GO:0045026)3.78928598
20epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.73125920
21binding of sperm to zona pellucida (GO:0007339)3.71836128
22cell-cell recognition (GO:0009988)3.71059251
23olfactory bulb development (GO:0021772)3.70134577
24spermatid development (GO:0007286)3.69044653
25neural tube formation (GO:0001841)3.68055789
26dendritic spine morphogenesis (GO:0060997)3.58934772
27gamma-aminobutyric acid transport (GO:0015812)3.58134721
28neuron recognition (GO:0008038)3.57769356
29DNA methylation involved in gamete generation (GO:0043046)3.56743263
30motile cilium assembly (GO:0044458)3.55627766
31negative regulation of synaptic transmission, GABAergic (GO:0032229)3.55297910
32protein localization to synapse (GO:0035418)3.52658593
33synapse assembly (GO:0007416)3.50091600
34head development (GO:0060322)3.49851969
35microtubule depolymerization (GO:0007019)3.48264901
36reproduction (GO:0000003)3.44150376
37pyrimidine nucleobase catabolic process (GO:0006208)3.41632459
38microtubule severing (GO:0051013)3.41536490
39axonal fasciculation (GO:0007413)3.38094033
40vocalization behavior (GO:0071625)3.35161118
41calcium ion-dependent exocytosis (GO:0017156)3.34291104
42regulation of short-term neuronal synaptic plasticity (GO:0048172)3.31133396
43negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.30612217
44cell migration in hindbrain (GO:0021535)3.29074377
45somite development (GO:0061053)3.28222862
46ventricular system development (GO:0021591)3.26432466
47positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.23771484
48establishment of mitochondrion localization (GO:0051654)3.22169267
49synaptonemal complex organization (GO:0070193)3.22129445
50presynaptic membrane assembly (GO:0097105)3.18718536
51cerebral cortex radially oriented cell migration (GO:0021799)3.14624454
52neurofilament cytoskeleton organization (GO:0060052)3.14250782
53retinal ganglion cell axon guidance (GO:0031290)3.14183716
54cell wall macromolecule catabolic process (GO:0016998)3.13572307
55cell wall macromolecule metabolic process (GO:0044036)3.13572307
56regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.12630859
57central nervous system projection neuron axonogenesis (GO:0021952)3.11675133
58G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.11335984
59spinal cord development (GO:0021510)3.08805210
60single fertilization (GO:0007338)3.08073944
61positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.05772073
62synaptonemal complex assembly (GO:0007130)3.05499238
63regulation of microtubule-based movement (GO:0060632)3.04137004
64sequestering of actin monomers (GO:0042989)3.03265093
65cell recognition (GO:0008037)3.02722359
66regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.00802389
67presynaptic membrane organization (GO:0097090)2.99469819
68sperm capacitation (GO:0048240)2.96381387
69calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.96366383
70dendrite morphogenesis (GO:0048813)2.96171435
71layer formation in cerebral cortex (GO:0021819)2.92939249
72negative regulation of inclusion body assembly (GO:0090084)2.91794212
73forebrain neuron differentiation (GO:0021879)2.91638742
74membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.91403797
75regulation of synapse structural plasticity (GO:0051823)2.89518929
76protein localization to cilium (GO:0061512)2.86814971
77neuronal action potential (GO:0019228)2.86130151
78postsynaptic membrane organization (GO:0001941)2.85814780
79protein polyglutamylation (GO:0018095)2.85536223
80synaptic vesicle exocytosis (GO:0016079)2.83223754
81response to pheromone (GO:0019236)2.83068912
82microtubule polymerization or depolymerization (GO:0031109)2.82271604
83transmission of nerve impulse (GO:0019226)2.80582852
84dendrite development (GO:0016358)2.80330817
85ionotropic glutamate receptor signaling pathway (GO:0035235)2.79806146
86regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.78771853
87auditory behavior (GO:0031223)2.77112015
88synaptic vesicle maturation (GO:0016188)2.76966193
89long-chain fatty acid biosynthetic process (GO:0042759)2.76077852
90startle response (GO:0001964)2.75143641
91locomotory exploration behavior (GO:0035641)2.74885584
92fertilization (GO:0009566)2.73952106
93negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.73380409
94negative regulation of translation, ncRNA-mediated (GO:0040033)2.73380409
95regulation of translation, ncRNA-mediated (GO:0045974)2.73380409
96negative regulation of neurotransmitter transport (GO:0051589)2.72737558
97sympathetic nervous system development (GO:0048485)2.71746978
98hippocampus development (GO:0021766)2.71475440
99regulation of synaptic vesicle exocytosis (GO:2000300)2.69547319
100negative regulation of microtubule polymerization (GO:0031115)2.69145911
101negative regulation of neurotransmitter secretion (GO:0046929)2.68479856
102eye photoreceptor cell differentiation (GO:0001754)2.68185337
103photoreceptor cell differentiation (GO:0046530)2.68185337
104negative regulation of telomere maintenance (GO:0032205)2.67106263
105transepithelial transport (GO:0070633)2.66400096
106glial cell proliferation (GO:0014009)2.66088889
107glycosphingolipid biosynthetic process (GO:0006688)2.64592011
108mechanosensory behavior (GO:0007638)2.62054561
109exploration behavior (GO:0035640)2.61901925
110negative regulation of oligodendrocyte differentiation (GO:0048715)2.61878408
111membrane depolarization during action potential (GO:0086010)2.60479553
112negative regulation of axon extension (GO:0030517)2.60423588
113negative regulation of dendrite development (GO:2000171)2.59743928
114kidney morphogenesis (GO:0060993)2.59313022
115nucleobase catabolic process (GO:0046113)2.58176142
116regulation of glutamate receptor signaling pathway (GO:1900449)2.58121788
117myelination (GO:0042552)2.58087532
118central nervous system neuron axonogenesis (GO:0021955)2.57775834
119spermatogenesis (GO:0007283)2.57574777
120positive regulation of oligodendrocyte differentiation (GO:0048714)2.57253699
121regulation of development, heterochronic (GO:0040034)2.56964198
122negative regulation of axon guidance (GO:1902668)2.56826229
123male gamete generation (GO:0048232)2.56526629
124regulation of action potential (GO:0098900)2.56451442
125neuronal ion channel clustering (GO:0045161)2.56418940
126regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.55975331
127positive regulation of mitochondrial fission (GO:0090141)2.55826168
128synaptic transmission, glutamatergic (GO:0035249)2.55709438
129establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.55538541
130mitochondrion transport along microtubule (GO:0047497)2.55538541
131regulation of rhodopsin mediated signaling pathway (GO:0022400)2.54585664
132axon ensheathment (GO:0008366)2.53996995
133ensheathment of neurons (GO:0007272)2.53996995
134glutamate receptor signaling pathway (GO:0007215)2.53826777
135activated T cell proliferation (GO:0050798)2.53750469
136limb bud formation (GO:0060174)2.53465353
137adult walking behavior (GO:0007628)2.53025648
138regulation of collateral sprouting (GO:0048670)2.51543787
139positive regulation of amino acid transport (GO:0051957)2.51475155
140positive regulation of synapse assembly (GO:0051965)2.51415950
141positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.49018291
142regulation of feeding behavior (GO:0060259)2.48551866
143negative regulation of axon extension involved in axon guidance (GO:0048843)2.48415911
144response to auditory stimulus (GO:0010996)2.47854423
145rhodopsin mediated signaling pathway (GO:0016056)2.47734122
146negative regulation of axonogenesis (GO:0050771)2.47129371
147heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.47001086
148regulation of timing of cell differentiation (GO:0048505)2.46117412
149detection of light stimulus involved in sensory perception (GO:0050962)2.45952984
150detection of light stimulus involved in visual perception (GO:0050908)2.45952984
151negative regulation of astrocyte differentiation (GO:0048712)2.45319686
152neuron-neuron synaptic transmission (GO:0007270)2.45289058
153negative regulation of glial cell differentiation (GO:0045686)2.44063067
154regulation of telomere maintenance (GO:0032204)2.43435856
155regulation of glutamate secretion (GO:0014048)2.43252388
156regulation of synaptic transmission, glutamatergic (GO:0051966)2.39695410
157synapse organization (GO:0050808)2.39612607
158nonmotile primary cilium assembly (GO:0035058)2.39091478
159protein insertion into membrane (GO:0051205)2.38406347
160regulation of synapse maturation (GO:0090128)2.37768969

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.88671090
2GBX2_23144817_ChIP-Seq_PC3_Human2.84360869
3IGF1R_20145208_ChIP-Seq_DFB_Human2.75534143
4MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.70614374
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.59277875
6TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.52002846
7ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.40081254
8CBX2_27304074_Chip-Seq_ESCs_Mouse2.30845529
9REST_21632747_ChIP-Seq_MESCs_Mouse2.23527560
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.22084796
11NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.10393476
12VDR_22108803_ChIP-Seq_LS180_Human2.09452049
13JARID2_20064375_ChIP-Seq_MESCs_Mouse2.09216329
14SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.96807985
15RNF2_27304074_Chip-Seq_NSC_Mouse1.94206456
16SUZ12_27294783_Chip-Seq_ESCs_Mouse1.91171489
17EZH2_27294783_Chip-Seq_ESCs_Mouse1.89880731
18CTBP2_25329375_ChIP-Seq_LNCAP_Human1.87168903
19RNF2_27304074_Chip-Seq_ESCs_Mouse1.82134264
20ZFP57_27257070_Chip-Seq_ESCs_Mouse1.81735676
21RBPJ_22232070_ChIP-Seq_NCS_Mouse1.79008012
22TAF15_26573619_Chip-Seq_HEK293_Human1.78276605
23RNF2_18974828_ChIP-Seq_MESCs_Mouse1.75501624
24EZH2_18974828_ChIP-Seq_MESCs_Mouse1.75501624
25SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.73535178
26SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.71881879
27JARID2_20075857_ChIP-Seq_MESCs_Mouse1.69631667
28BMI1_23680149_ChIP-Seq_NPCS_Mouse1.69555377
29CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.62027126
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.60520119
31DROSHA_22980978_ChIP-Seq_HELA_Human1.60515719
32SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.60335302
33MTF2_20144788_ChIP-Seq_MESCs_Mouse1.58836892
34GATA1_26923725_Chip-Seq_HPCs_Mouse1.58155013
35EED_16625203_ChIP-ChIP_MESCs_Mouse1.57068722
36ZNF274_21170338_ChIP-Seq_K562_Hela1.54460411
37GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.51834713
38SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.50229547
39REST_18959480_ChIP-ChIP_MESCs_Mouse1.48609788
40SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.48414631
41FUS_26573619_Chip-Seq_HEK293_Human1.47022581
42SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.41587059
43SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.41395752
44SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40658841
45TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39969021
46POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.39969021
47ER_23166858_ChIP-Seq_MCF-7_Human1.38570968
48SMAD3_21741376_ChIP-Seq_EPCs_Human1.36650570
49PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.35303876
50STAT6_21828071_ChIP-Seq_BEAS2B_Human1.34909242
51RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.30290217
52IRF1_19129219_ChIP-ChIP_H3396_Human1.30197294
53MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.28465133
54POU3F2_20337985_ChIP-ChIP_501MEL_Human1.28275816
55TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27940548
56EWS_26573619_Chip-Seq_HEK293_Human1.27906889
57PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.27409855
58RARB_27405468_Chip-Seq_BRAIN_Mouse1.27260830
59P300_19829295_ChIP-Seq_ESCs_Human1.26988276
60CBP_20019798_ChIP-Seq_JUKART_Human1.24753519
61IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.24753519
62OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23924948
63TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.23673009
64CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.22481421
65TOP2B_26459242_ChIP-Seq_MCF-7_Human1.21511321
66HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.19525576
67PIAS1_25552417_ChIP-Seq_VCAP_Human1.19285570
68SMAD4_21799915_ChIP-Seq_A2780_Human1.18341146
69KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.17742771
70CDX2_19796622_ChIP-Seq_MESCs_Mouse1.17017480
71PRDM14_20953172_ChIP-Seq_ESCs_Human1.16743888
72RING1B_27294783_Chip-Seq_ESCs_Mouse1.16686932
73CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16051026
74SALL1_21062744_ChIP-ChIP_HESCs_Human1.14592294
75NANOG_18555785_Chip-Seq_ESCs_Mouse1.14468406
76CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.14213080
77NR3C1_21868756_ChIP-Seq_MCF10A_Human1.14118067
78FLI1_27457419_Chip-Seq_LIVER_Mouse1.13337220
79MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.13230551
80EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.12900875
81BCAT_22108803_ChIP-Seq_LS180_Human1.12076862
82RING1B_27294783_Chip-Seq_NPCs_Mouse1.11744914
83SOX9_26525672_Chip-Seq_HEART_Mouse1.11592895
84SOX2_21211035_ChIP-Seq_LN229_Gbm1.10091124
85PCGF2_27294783_Chip-Seq_ESCs_Mouse1.09520036
86TCF4_23295773_ChIP-Seq_U87_Human1.09382635
87P53_22127205_ChIP-Seq_FIBROBLAST_Human1.09289720
88TP63_19390658_ChIP-ChIP_HaCaT_Human1.08897537
89RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.08624656
90AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.07445862
91TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.06310637
92SMAD3_21741376_ChIP-Seq_ESCs_Human1.04330717
93STAT3_23295773_ChIP-Seq_U87_Human1.04085030
94ETV2_25802403_ChIP-Seq_MESCs_Mouse1.03845332
95MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.02761961
96CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.01636145
97CMYC_18555785_Chip-Seq_ESCs_Mouse0.99930377
98FLI1_21867929_ChIP-Seq_TH2_Mouse0.99756839
99EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.99703233
100GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.98798338
101TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.97925280
102AHR_22903824_ChIP-Seq_MCF-7_Human0.97738580
103IKZF1_21737484_ChIP-ChIP_HCT116_Human0.97704995
104ARNT_22903824_ChIP-Seq_MCF-7_Human0.96596993
105UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.95097458
106TAL1_26923725_Chip-Seq_HPCs_Mouse0.94642890
107CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.94538976
108E2F1_18555785_Chip-Seq_ESCs_Mouse0.94510014
109TP53_22573176_ChIP-Seq_HFKS_Human0.94416926
110AR_19668381_ChIP-Seq_PC3_Human0.94292139
111TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.93547989
112TCF4_22108803_ChIP-Seq_LS180_Human0.93031169
113RUNX2_22187159_ChIP-Seq_PCA_Human0.91434101
114POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.91423701
115KDM2B_26808549_Chip-Seq_REH_Human0.90934602
116VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.90876356
117STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.90837982
118WDR5_24793694_ChIP-Seq_LNCAP_Human0.90488608
119SUZ12_18555785_Chip-Seq_ESCs_Mouse0.90459112
120SOX2_19829295_ChIP-Seq_ESCs_Human0.90228855
121NANOG_19829295_ChIP-Seq_ESCs_Human0.90228855
122AR_21572438_ChIP-Seq_LNCaP_Human0.89865486
123KLF5_20875108_ChIP-Seq_MESCs_Mouse0.89844395
124AR_25329375_ChIP-Seq_VCAP_Human0.89301379
125BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.88399423

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization4.41662531
2MP0003880_abnormal_central_pattern3.41370301
3MP0004859_abnormal_synaptic_plasticity3.37197542
4MP0004270_analgesia3.08119488
5MP0005423_abnormal_somatic_nervous3.01488700
6MP0000778_abnormal_nervous_system2.84363536
7MP0003635_abnormal_synaptic_transmissio2.36972929
8MP0003698_abnormal_male_reproductive2.17862168
9MP0008877_abnormal_DNA_methylation2.17748918
10MP0002734_abnormal_mechanical_nocicepti2.16479553
11MP0001486_abnormal_startle_reflex2.15359121
12MP0002653_abnormal_ependyma_morphology2.13725574
13MP0002063_abnormal_learning/memory/cond2.09066630
14MP0002102_abnormal_ear_morphology1.97456537
15MP0009046_muscle_twitch1.94632118
16MP0005551_abnormal_eye_electrophysiolog1.93000847
17MP0001529_abnormal_vocalization1.91903941
18MP0001968_abnormal_touch/_nociception1.87853764
19MP0002572_abnormal_emotion/affect_behav1.85490715
20MP0002184_abnormal_innervation1.83569417
21MP0006276_abnormal_autonomic_nervous1.83022819
22MP0002272_abnormal_nervous_system1.82814547
23MP0004133_heterotaxia1.79927608
24MP0002064_seizures1.79483576
25MP0008995_early_reproductive_senescence1.77570130
26MP0009745_abnormal_behavioral_response1.76938938
27MP0003195_calcinosis1.75775806
28MP0001929_abnormal_gametogenesis1.69065612
29MP0002735_abnormal_chemical_nociception1.68965993
30MP0005394_taste/olfaction_phenotype1.68473917
31MP0005499_abnormal_olfactory_system1.68473917
32MP0008789_abnormal_olfactory_epithelium1.68421392
33MP0001984_abnormal_olfaction1.67564891
34MP0002882_abnormal_neuron_morphology1.66899871
35MP0004742_abnormal_vestibular_system1.65611716
36MP0003724_increased_susceptibility_to1.58890439
37MP0000955_abnormal_spinal_cord1.54024231
38MP0001188_hyperpigmentation1.53584944
39MP0004885_abnormal_endolymph1.51400367
40MP0000569_abnormal_digit_pigmentation1.49995364
41MP0001440_abnormal_grooming_behavior1.49535226
42MP0001905_abnormal_dopamine_level1.49033236
43MP0000465_gastrointestinal_hemorrhage1.48034241
44MP0002752_abnormal_somatic_nervous1.48000695
45MP0002557_abnormal_social/conspecific_i1.44404547
46MP0002067_abnormal_sensory_capabilities1.43582235
47MP0004811_abnormal_neuron_physiology1.43386292
48MP0002733_abnormal_thermal_nociception1.43220698
49MP0003861_abnormal_nervous_system1.41671584
50MP0002736_abnormal_nociception_after1.39451989
51MP0002152_abnormal_brain_morphology1.38834698
52MP0005645_abnormal_hypothalamus_physiol1.38355774
53MP0000920_abnormal_myelination1.38181373
54MP0006072_abnormal_retinal_apoptosis1.38060990
55MP0005409_darkened_coat_color1.37289014
56MP0002210_abnormal_sex_determination1.36201733
57MP0001485_abnormal_pinna_reflex1.33252171
58MP0005253_abnormal_eye_physiology1.30907214
59MP0003011_delayed_dark_adaptation1.30290757
60MP0005386_behavior/neurological_phenoty1.29871244
61MP0004924_abnormal_behavior1.29871244
62MP0001970_abnormal_pain_threshold1.28200569
63MP0005367_renal/urinary_system_phenotyp1.25551601
64MP0000516_abnormal_urinary_system1.25551601
65MP0002229_neurodegeneration1.23762050
66MP0002161_abnormal_fertility/fecundity1.22056029
67MP0001501_abnormal_sleep_pattern1.21761364
68MP0003634_abnormal_glial_cell1.20211153
69MP0003938_abnormal_ear_development1.18614199
70MP0005195_abnormal_posterior_eye1.18490339
71MP0000631_abnormal_neuroendocrine_gland1.16936202
72MP0002876_abnormal_thyroid_physiology1.16448742
73MP0006292_abnormal_olfactory_placode1.15676863
74MP0003567_abnormal_fetal_cardiomyocyte1.14672009
75MP0005084_abnormal_gallbladder_morpholo1.14379721
76MP0002928_abnormal_bile_duct1.14210073
77MP0002638_abnormal_pupillary_reflex1.13252920
78MP0001963_abnormal_hearing_physiology1.12827846
79MP0002751_abnormal_autonomic_nervous1.11011675
80MP0001145_abnormal_male_reproductive1.10925017
81MP0002066_abnormal_motor_capabilities/c1.10201259
82MP0005646_abnormal_pituitary_gland1.08866112
83MP0005167_abnormal_blood-brain_barrier1.04928602
84MP0005623_abnormal_meninges_morphology1.04596262
85MP0003787_abnormal_imprinting1.04202998
86MP0004858_abnormal_nervous_system1.01993688
87MP0000026_abnormal_inner_ear1.01602616
88MP0002909_abnormal_adrenal_gland1.00860732
89MP0003329_amyloid_beta_deposits1.00584935
90MP0005187_abnormal_penis_morphology1.00187058
91MP0008569_lethality_at_weaning0.99097733
92MP0003890_abnormal_embryonic-extraembry0.98935867
93MP0008872_abnormal_physiological_respon0.98505614
94MP0003122_maternal_imprinting0.98346742
95MP0000653_abnormal_sex_gland0.96403872
96MP0000462_abnormal_digestive_system0.95864625
97MP0003632_abnormal_nervous_system0.95445419
98MP0005171_absent_coat_pigmentation0.95222513
99MP0001502_abnormal_circadian_rhythm0.93218052
100MP0000537_abnormal_urethra_morphology0.90046691
101MP0004134_abnormal_chest_morphology0.89927301
102MP0002069_abnormal_eating/drinking_beha0.86301178
103MP0003119_abnormal_digestive_system0.86177520
104MP0000566_synostosis0.84820190
105MP0002160_abnormal_reproductive_system0.83239689
106MP0002822_catalepsy0.82938741
107MP0004147_increased_porphyrin_level0.82710049
108MP0001986_abnormal_taste_sensitivity0.80863734
109MP0005391_vision/eye_phenotype0.80337052
110MP0002938_white_spotting0.80113132
111MP0003937_abnormal_limbs/digits/tail_de0.79559501
112MP0003631_nervous_system_phenotype0.77509695
113MP0000049_abnormal_middle_ear0.77053524
114MP0003121_genomic_imprinting0.76215434
115MP0003950_abnormal_plasma_membrane0.75621081
116MP0003283_abnormal_digestive_organ0.75203841
117MP0003633_abnormal_nervous_system0.75091882
118MP0001324_abnormal_eye_pigmentation0.74635303
119MP0003315_abnormal_perineum_morphology0.74472273
120MP0004142_abnormal_muscle_tone0.74232598
121MP0001293_anophthalmia0.73171993
122MP0004085_abnormal_heartbeat0.67862798
123MP0004145_abnormal_muscle_electrophysio0.65119565
124MP0004043_abnormal_pH_regulation0.64565452
125MP0002277_abnormal_respiratory_mucosa0.61735505
126MP0010770_preweaning_lethality0.56095150

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)6.11912348
2Dynein arm defect of respiratory motile cilia (HP:0012255)6.05240967
3Absent/shortened dynein arms (HP:0200106)6.05240967
4Abnormal respiratory epithelium morphology (HP:0012253)4.49088824
5Abnormal respiratory motile cilium morphology (HP:0005938)4.49088824
6Abnormal respiratory motile cilium physiology (HP:0012261)4.39287433
7Abnormal ciliary motility (HP:0012262)3.82753879
8Rhinitis (HP:0012384)3.43284986
9Hyperventilation (HP:0002883)3.39525787
10Pancreatic cysts (HP:0001737)3.31648049
11Abnormality of the corticospinal tract (HP:0002492)3.19641268
12Chronic hepatic failure (HP:0100626)3.16994147
13Degeneration of the lateral corticospinal tracts (HP:0002314)3.06622945
14Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.06622945
15Nephronophthisis (HP:0000090)3.05576715
16Myokymia (HP:0002411)2.94745918
17Agitation (HP:0000713)2.80969891
18Chronic bronchitis (HP:0004469)2.64991234
19Infertility (HP:0000789)2.61144480
20Epileptic encephalopathy (HP:0200134)2.59129326
21Medial flaring of the eyebrow (HP:0010747)2.56027308
22Thyroid-stimulating hormone excess (HP:0002925)2.52355749
23Gait imbalance (HP:0002141)2.51290580
24Progressive cerebellar ataxia (HP:0002073)2.46980790
25Type II lissencephaly (HP:0007260)2.45264927
26Ankle clonus (HP:0011448)2.43892189
27Amyotrophic lateral sclerosis (HP:0007354)2.43495740
28Dyschromatopsia (HP:0007641)2.35667674
29Methylmalonic acidemia (HP:0002912)2.33246825
30Abnormality of macular pigmentation (HP:0008002)2.29635830
31Congenital stationary night blindness (HP:0007642)2.29240479
32Hypothermia (HP:0002045)2.28486767
33Tented upper lip vermilion (HP:0010804)2.27527383
34Focal seizures (HP:0007359)2.25827247
35Cystic liver disease (HP:0006706)2.25140904
36Limb dystonia (HP:0002451)2.25079377
37Supranuclear gaze palsy (HP:0000605)2.24828292
38Decreased central vision (HP:0007663)2.24131880
39Abnormality of midbrain morphology (HP:0002418)2.22829557
40Molar tooth sign on MRI (HP:0002419)2.22829557
41Renal cortical cysts (HP:0000803)2.22741774
42Lissencephaly (HP:0001339)2.22059396
43Pendular nystagmus (HP:0012043)2.21881096
44Spastic gait (HP:0002064)2.21852613
45Broad-based gait (HP:0002136)2.21790774
46Failure to thrive in infancy (HP:0001531)2.21671119
47Hypsarrhythmia (HP:0002521)2.20556648
48Abnormality of the renal cortex (HP:0011035)2.19893093
49Abnormality of the renal medulla (HP:0100957)2.19756473
50Mutism (HP:0002300)2.17068958
51Insidious onset (HP:0003587)2.14918984
52Termporal pattern (HP:0011008)2.14918984
53Neurofibrillary tangles (HP:0002185)2.14514662
54Decreased circulating renin level (HP:0003351)2.14483572
55Exotropia (HP:0000577)2.14094727
56Sensory axonal neuropathy (HP:0003390)2.13465771
57Choroideremia (HP:0001139)2.11955886
58Inability to walk (HP:0002540)2.10342656
59Occipital encephalocele (HP:0002085)2.10075863
60Anencephaly (HP:0002323)2.08272820
61Focal motor seizures (HP:0011153)2.07472337
62Hypoplasia of the brainstem (HP:0002365)2.06921207
63Aplasia/Hypoplasia of the brainstem (HP:0007362)2.06921207
64Dyskinesia (HP:0100660)2.06535148
65Pachygyria (HP:0001302)2.06376637
66Bony spicule pigmentary retinopathy (HP:0007737)2.05999563
67Genital tract atresia (HP:0001827)2.04707903
68Methylmalonic aciduria (HP:0012120)2.03274198
69Vaginal atresia (HP:0000148)2.03115890
70Severe combined immunodeficiency (HP:0004430)2.02084279
71Atonic seizures (HP:0010819)2.00104983
72Stomach cancer (HP:0012126)2.00037815
73Abnormal hair whorl (HP:0010721)1.98848842
74Abnormality of the labia minora (HP:0012880)1.98698183
75Thyroiditis (HP:0100646)1.98282248
76Dialeptic seizures (HP:0011146)1.97659986
77Pancreatic fibrosis (HP:0100732)1.95845424
78Narrow forehead (HP:0000341)1.95680798
79Congenital primary aphakia (HP:0007707)1.95458877
80Retinal dysplasia (HP:0007973)1.94653967
81Excessive salivation (HP:0003781)1.93617553
82Drooling (HP:0002307)1.93617553
83Keratoconus (HP:0000563)1.92834085
84Increased corneal curvature (HP:0100692)1.92834085
85Abnormal biliary tract physiology (HP:0012439)1.92084033
86Bile duct proliferation (HP:0001408)1.92084033
87Peripheral hypomyelination (HP:0007182)1.91409573
88Abnormal eating behavior (HP:0100738)1.91084566
89Sclerocornea (HP:0000647)1.91071422
90Oligodactyly (hands) (HP:0001180)1.90020282
91Male pseudohermaphroditism (HP:0000037)1.89873468
92Hepatoblastoma (HP:0002884)1.89521156
93Central scotoma (HP:0000603)1.88402520
94Intestinal atresia (HP:0011100)1.88346500
95Protruding tongue (HP:0010808)1.86740326
96Severe visual impairment (HP:0001141)1.86123936
97Male infertility (HP:0003251)1.85663072
98Urinary bladder sphincter dysfunction (HP:0002839)1.84982317
99Abnormality of the vitamin B12 metabolism (HP:0004341)1.82743472
100Cerebral hypomyelination (HP:0006808)1.82727960
101Akinesia (HP:0002304)1.82577038
102Aqueductal stenosis (HP:0002410)1.82142320
103Abnormality of the lower motor neuron (HP:0002366)1.79024745
104Cortical dysplasia (HP:0002539)1.78196924
105Nephrogenic diabetes insipidus (HP:0009806)1.78106135
106Broad alveolar ridges (HP:0000187)1.77937556
107Esotropia (HP:0000565)1.77836895
108Optic nerve hypoplasia (HP:0000609)1.76428293
109Polyphagia (HP:0002591)1.75858764
110Anophthalmia (HP:0000528)1.75310693
111Hemiparesis (HP:0001269)1.74496035
112Spastic tetraplegia (HP:0002510)1.73833820
113Polymicrogyria (HP:0002126)1.73566534
114Gaze-evoked nystagmus (HP:0000640)1.72778315
115Absent speech (HP:0001344)1.72555772
116Morphological abnormality of the middle ear (HP:0008609)1.72259643
117Abnormal rod and cone electroretinograms (HP:0008323)1.70271602
118Renal hypoplasia (HP:0000089)1.70202664
119Febrile seizures (HP:0002373)1.70165347
120Abnormality of vitamin B metabolism (HP:0004340)1.69926040
121Absent rod-and cone-mediated responses on ERG (HP:0007688)1.69887058
122Lower limb muscle weakness (HP:0007340)1.69070911
123Abolished electroretinogram (ERG) (HP:0000550)1.68175777
124Postaxial hand polydactyly (HP:0001162)1.67270258
125Absent septum pellucidum (HP:0001331)1.67033354
126Midline defect of the nose (HP:0004122)1.66961419
127Specific learning disability (HP:0001328)1.64884542
128Progressive inability to walk (HP:0002505)1.64761779
129Overriding aorta (HP:0002623)1.63506264
130Action tremor (HP:0002345)1.63188361
131Aplasia/Hypoplasia of the lens (HP:0008063)1.63087909
132True hermaphroditism (HP:0010459)1.62426992
133Attenuation of retinal blood vessels (HP:0007843)1.59955236
134Postaxial foot polydactyly (HP:0001830)1.59277901
135Genetic anticipation (HP:0003743)1.58200841
136Heterotopia (HP:0002282)1.57394038
137Anosmia (HP:0000458)1.57254817
138Poor coordination (HP:0002370)1.55839365
139Cerebral inclusion bodies (HP:0100314)1.55272255
140Amblyopia (HP:0000646)1.55003395
141Abnormality of the septum pellucidum (HP:0007375)1.53863429
142Widely spaced teeth (HP:0000687)1.53658289
143Urinary urgency (HP:0000012)1.50161367
144Fetal akinesia sequence (HP:0001989)1.48851548
145Hypoplasia of the corpus callosum (HP:0002079)1.48626164
146Morphological abnormality of the pyramidal tract (HP:0002062)1.48057503
147Aplasia/Hypoplasia of the tongue (HP:0010295)1.47394789
148Visual hallucinations (HP:0002367)1.47038265
149EEG with generalized epileptiform discharges (HP:0011198)1.46949537
150Epileptiform EEG discharges (HP:0011182)1.46934252

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK15.99995274
2PNCK3.33421510
3STK392.94933617
4ICK2.66616595
5PRKD32.66052152
6MAP4K22.61049106
7FRK2.57065063
8MAPK132.23522668
9TIE12.20366400
10DYRK22.17594148
11PINK12.04919991
12TAOK32.04260698
13TRIM282.02727715
14NTRK21.94100074
15PDK41.89258573
16PDK31.89258573
17IRAK21.87384839
18NTRK31.75181539
19WNK41.74124439
20EPHA41.72768189
21OXSR11.71824180
22EPHA31.69724136
23TESK11.66962382
24MAP2K71.64650643
25MAP3K91.62976560
26CASK1.60100757
27PLK41.56477922
28BCR1.52635973
29MAP3K41.51108307
30ADRBK21.50341795
31MINK11.50278089
32TNIK1.45389886
33SIK31.42355243
34UHMK11.41017398
35PAK61.37903133
36CAMKK21.35411794
37PKN11.30873464
38TYRO31.29317152
39PDK21.20618613
40PRPF4B1.18019139
41ERBB31.15200937
42BRD41.11825415
43CDK191.10492584
44TLK11.09879782
45TXK1.09258781
46GRK61.07760800
47BMPR1B1.07254068
48MAP2K41.04850423
49CSNK1G21.04772333
50NUAK11.04368566
51SGK21.03306999
52AKT31.03181401
53WNK31.01982745
54PLK21.00132167
55DYRK1B0.99401564
56CSNK1G30.95645134
57IRAK10.95588283
58LATS20.95035840
59PHKG20.94925527
60PHKG10.94925527
61CDK50.94856188
62LIMK10.91260634
63KSR10.90446015
64SGK4940.90284594
65SGK2230.90284594
66PTK2B0.90117054
67WNK10.86778430
68BCKDK0.86079470
69CSNK1A1L0.83879077
70INSRR0.82383242
71CAMK2B0.82234691
72CAMK1G0.80998154
73NEK60.77623436
74DAPK20.77529747
75TAOK10.77432317
76SIK20.76294394
77NTRK10.74917047
78ACVR1B0.73655996
79MARK20.73631890
80CAMK2A0.71026054
81CDK30.70250982
82PRKCG0.69768170
83BUB10.68573464
84FES0.68251963
85MAPK150.67717186
86CDK140.67690656
87CHEK20.67117678
88CAMK40.67054697
89DYRK1A0.66932266
90TNK20.66643832
91CDK180.66224396
92CCNB10.63710579
93CDK150.63636468
94SRPK10.63401295
95PAK30.59394783
96CAMKK10.59035434
97PRKCZ0.58642211
98CSNK1G10.57405611
99PLK30.57401893
100CDK11A0.55118896
101CAMK2D0.54611257
102ADRBK10.53695475
103STK380.53393556
104PRKCE0.52874207
105STK110.51557701
106FGFR20.50925178
107MATK0.49898020
108MKNK10.49317858
109CAMK10.47836717
110MAP3K60.45733863
111BMPR20.45605421
112EPHB20.45057949
113SGK30.44424170
114ROCK20.44280002
115PRKACA0.44230083
116EPHB10.43935421
117DYRK30.43278750
118PRKD20.42956231
119MAP3K70.42896517
120LYN0.42167066
121YES10.41658968
122ERBB20.41467298
123FYN0.41305448
124CSNK1D0.39783968
125NME10.39495564
126KSR20.39452173
127SYK0.38156789
128RPS6KA40.37979002
129GRK10.37091910
130GSK3B0.36858208
131MAP4K10.36819664
132TEC0.36782695
133PRKG10.36639158
134CSNK1A10.36543981
135MAPK100.36436506
136STK160.36321046
137GRK50.36175409
138IGF1R0.33735538
139LCK0.33527774
140PRKAA10.32914977
141CSNK1E0.32306501
142RPS6KA20.32216717
143MAP2K60.31952524
144MAPK80.31921675
145CDK10.31365779
146PBK0.31119083
147TTK0.30504845
148MAPKAPK50.30358472
149MAPK90.29320722

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047443.20304474
2Taurine and hypotaurine metabolism_Homo sapiens_hsa004303.05550475
3Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.60762627
4Nicotine addiction_Homo sapiens_hsa050332.41250436
5Axon guidance_Homo sapiens_hsa043602.35290138
6Synaptic vesicle cycle_Homo sapiens_hsa047212.34806702
7Glutamatergic synapse_Homo sapiens_hsa047242.17241395
8Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.92780895
9Olfactory transduction_Homo sapiens_hsa047401.91295577
10Circadian entrainment_Homo sapiens_hsa047131.88315740
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.80676793
12Ether lipid metabolism_Homo sapiens_hsa005651.75987414
13Morphine addiction_Homo sapiens_hsa050321.74853562
14Dopaminergic synapse_Homo sapiens_hsa047281.70959832
15Serotonergic synapse_Homo sapiens_hsa047261.70915949
16Maturity onset diabetes of the young_Homo sapiens_hsa049501.67855032
17GABAergic synapse_Homo sapiens_hsa047271.67586429
18Amphetamine addiction_Homo sapiens_hsa050311.66191653
19Long-term potentiation_Homo sapiens_hsa047201.63678750
20Cholinergic synapse_Homo sapiens_hsa047251.57397898
21Regulation of autophagy_Homo sapiens_hsa041401.49013512
22Oocyte meiosis_Homo sapiens_hsa041141.47566192
23Butanoate metabolism_Homo sapiens_hsa006501.45186208
24Dorso-ventral axis formation_Homo sapiens_hsa043201.39206119
25Basal transcription factors_Homo sapiens_hsa030221.38046780
26Collecting duct acid secretion_Homo sapiens_hsa049661.38037357
27Cocaine addiction_Homo sapiens_hsa050301.37335148
28Taste transduction_Homo sapiens_hsa047421.32984579
29Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.31672209
30Steroid biosynthesis_Homo sapiens_hsa001001.28344702
31Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.25611566
32Fat digestion and absorption_Homo sapiens_hsa049751.24846867
33Insulin secretion_Homo sapiens_hsa049111.23408068
34Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.20947845
35Long-term depression_Homo sapiens_hsa047301.19167189
36Hedgehog signaling pathway_Homo sapiens_hsa043401.18998977
37Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.17223473
38Vitamin B6 metabolism_Homo sapiens_hsa007501.17061262
39Gap junction_Homo sapiens_hsa045401.16217472
40Renin secretion_Homo sapiens_hsa049241.15520298
41Protein export_Homo sapiens_hsa030601.14170848
42Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.14085697
43Salivary secretion_Homo sapiens_hsa049701.13816173
44Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.09959784
45Huntingtons disease_Homo sapiens_hsa050161.09333668
46Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.08503076
47Gastric acid secretion_Homo sapiens_hsa049711.04610530
48Sphingolipid metabolism_Homo sapiens_hsa006001.04506221
49ErbB signaling pathway_Homo sapiens_hsa040121.02779168
50Renal cell carcinoma_Homo sapiens_hsa052110.99833596
51Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.99377027
52Oxytocin signaling pathway_Homo sapiens_hsa049210.99314635
53mRNA surveillance pathway_Homo sapiens_hsa030150.98835040
54Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.97294791
55Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.95256154
56Fanconi anemia pathway_Homo sapiens_hsa034600.94751863
57Cardiac muscle contraction_Homo sapiens_hsa042600.94718841
58Tryptophan metabolism_Homo sapiens_hsa003800.94452530
59Vibrio cholerae infection_Homo sapiens_hsa051100.93158065
60Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.92391911
61Nitrogen metabolism_Homo sapiens_hsa009100.92193252
62Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.90894311
63Aldosterone synthesis and secretion_Homo sapiens_hsa049250.89199921
64Vitamin digestion and absorption_Homo sapiens_hsa049770.89012685
65Wnt signaling pathway_Homo sapiens_hsa043100.88599197
66Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.85529562
67Estrogen signaling pathway_Homo sapiens_hsa049150.84737929
68Calcium signaling pathway_Homo sapiens_hsa040200.84732183
69Ras signaling pathway_Homo sapiens_hsa040140.84356740
70Mineral absorption_Homo sapiens_hsa049780.81753641
71Melanogenesis_Homo sapiens_hsa049160.81602783
72Caffeine metabolism_Homo sapiens_hsa002320.79793190
73Tight junction_Homo sapiens_hsa045300.79324916
74Glycerolipid metabolism_Homo sapiens_hsa005610.79228902
75Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.79097792
76GnRH signaling pathway_Homo sapiens_hsa049120.78311849
77Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.78093246
78Phosphatidylinositol signaling system_Homo sapiens_hsa040700.77806194
79Alcoholism_Homo sapiens_hsa050340.77804925
80RNA polymerase_Homo sapiens_hsa030200.76716530
81cAMP signaling pathway_Homo sapiens_hsa040240.76609528
82Basal cell carcinoma_Homo sapiens_hsa052170.75688833
83Selenocompound metabolism_Homo sapiens_hsa004500.75372413
84Endocytosis_Homo sapiens_hsa041440.74536933
85SNARE interactions in vesicular transport_Homo sapiens_hsa041300.74017884
86Choline metabolism in cancer_Homo sapiens_hsa052310.73792586
87Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.72044748
88Phospholipase D signaling pathway_Homo sapiens_hsa040720.72023870
89Sphingolipid signaling pathway_Homo sapiens_hsa040710.72016989
90Linoleic acid metabolism_Homo sapiens_hsa005910.71822877
91alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.70750356
92Circadian rhythm_Homo sapiens_hsa047100.70552115
93Glycerophospholipid metabolism_Homo sapiens_hsa005640.70385542
94Hippo signaling pathway_Homo sapiens_hsa043900.69421257
95ABC transporters_Homo sapiens_hsa020100.68700257
96Oxidative phosphorylation_Homo sapiens_hsa001900.68559297
97cGMP-PKG signaling pathway_Homo sapiens_hsa040220.66430003
98Notch signaling pathway_Homo sapiens_hsa043300.66049623
99Type II diabetes mellitus_Homo sapiens_hsa049300.65566375
100Vascular smooth muscle contraction_Homo sapiens_hsa042700.63776283
101MAPK signaling pathway_Homo sapiens_hsa040100.62909928
102Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.62794091
103Alzheimers disease_Homo sapiens_hsa050100.62266878
104Colorectal cancer_Homo sapiens_hsa052100.61128341
105Peroxisome_Homo sapiens_hsa041460.59783076
106Glioma_Homo sapiens_hsa052140.59514489
107Ovarian steroidogenesis_Homo sapiens_hsa049130.59400574
108Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.59324799
109Steroid hormone biosynthesis_Homo sapiens_hsa001400.58268739
110Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.57709429
111Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.56778283
112Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.56104794
113Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.56017272
114Arachidonic acid metabolism_Homo sapiens_hsa005900.55707654
115Carbohydrate digestion and absorption_Homo sapiens_hsa049730.54434115
116Thyroid hormone signaling pathway_Homo sapiens_hsa049190.54308458
117Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.53600221
118Chemical carcinogenesis_Homo sapiens_hsa052040.52313557
119Purine metabolism_Homo sapiens_hsa002300.51618342
120Parkinsons disease_Homo sapiens_hsa050120.51345900
121Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.48075845
122Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.47819970
123Spliceosome_Homo sapiens_hsa030400.47550450
124Endometrial cancer_Homo sapiens_hsa052130.47547123
125Retinol metabolism_Homo sapiens_hsa008300.44586569
126Rap1 signaling pathway_Homo sapiens_hsa040150.41431015
127Pancreatic secretion_Homo sapiens_hsa049720.40919352
128Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.40605725
129Starch and sucrose metabolism_Homo sapiens_hsa005000.37663483
130Primary immunodeficiency_Homo sapiens_hsa053400.35760156
131Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.29721372
132Renin-angiotensin system_Homo sapiens_hsa046140.29291320
133Chemokine signaling pathway_Homo sapiens_hsa040620.28629950

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