NLE1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)4.80806559
2nucleobase biosynthetic process (GO:0046112)4.44462173
3ribosome biogenesis (GO:0042254)4.40053450
4formation of translation preinitiation complex (GO:0001731)4.39472771
5mitotic chromosome condensation (GO:0007076)4.36965154
6IMP biosynthetic process (GO:0006188)4.31705364
7DNA strand elongation involved in DNA replication (GO:0006271)4.29703734
8ribosomal small subunit assembly (GO:0000028)4.25327364
9telomere maintenance via semi-conservative replication (GO:0032201)4.23897510
10DNA strand elongation (GO:0022616)4.17395369
11folic acid-containing compound biosynthetic process (GO:0009396)4.15170625
12maturation of SSU-rRNA (GO:0030490)4.14622788
13DNA replication initiation (GO:0006270)4.14083672
14purine nucleobase biosynthetic process (GO:0009113)4.03037251
15pseudouridine synthesis (GO:0001522)4.01035592
16protein localization to kinetochore (GO:0034501)3.82679094
17sister chromatid segregation (GO:0000819)3.78467390
18regulation of mitochondrial translation (GO:0070129)3.75031414
19DNA replication checkpoint (GO:0000076)3.74264235
20DNA unwinding involved in DNA replication (GO:0006268)3.73690072
21telomere maintenance via recombination (GO:0000722)3.69881484
22* ribonucleoprotein complex biogenesis (GO:0022613)3.68817920
23rRNA processing (GO:0006364)3.60431781
24protein complex localization (GO:0031503)3.59443752
25IMP metabolic process (GO:0046040)3.55966730
26mitotic nuclear envelope disassembly (GO:0007077)3.53608066
27establishment of integrated proviral latency (GO:0075713)3.52469762
28ribosome assembly (GO:0042255)3.50263831
29telomere maintenance via telomere lengthening (GO:0010833)3.49111954
30mitotic metaphase plate congression (GO:0007080)3.49046986
31L-serine metabolic process (GO:0006563)3.48847270
32rRNA metabolic process (GO:0016072)3.48096412
33heterochromatin organization (GO:0070828)3.46772780
34proline biosynthetic process (GO:0006561)3.43532116
35regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.42633791
36negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.38711396
37mitotic recombination (GO:0006312)3.37811994
38maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.34015486
39nuclear pore organization (GO:0006999)3.29332382
40pore complex assembly (GO:0046931)3.29158119
41tRNA methylation (GO:0030488)3.27895249
42spliceosomal snRNP assembly (GO:0000387)3.27115406
43cellular protein complex localization (GO:0034629)3.24119806
44viral transcription (GO:0019083)3.23385874
45nucleotide-excision repair, DNA gap filling (GO:0006297)3.22480736
46somatic hypermutation of immunoglobulin genes (GO:0016446)3.20236612
47somatic diversification of immune receptors via somatic mutation (GO:0002566)3.20236612
48nuclear envelope disassembly (GO:0051081)3.20179664
49membrane disassembly (GO:0030397)3.20179664
50viral mRNA export from host cell nucleus (GO:0046784)3.19626815
51rRNA transcription (GO:0009303)3.18680366
52rRNA modification (GO:0000154)3.18327307
53DNA duplex unwinding (GO:0032508)3.17644545
54translational termination (GO:0006415)3.17409069
55DNA geometric change (GO:0032392)3.17113454
56protein localization to chromosome, centromeric region (GO:0071459)3.15861974
57kinetochore assembly (GO:0051382)3.15600818
58translational initiation (GO:0006413)3.12785483
59mitotic sister chromatid cohesion (GO:0007064)3.12329448
60replication fork processing (GO:0031297)3.11825971
61maturation of 5.8S rRNA (GO:0000460)3.09089052
62kinetochore organization (GO:0051383)3.09072584
63transcription from mitochondrial promoter (GO:0006390)3.08600915
64base-excision repair (GO:0006284)3.07507686
65DNA strand renaturation (GO:0000733)3.05428206
66tRNA aminoacylation for protein translation (GO:0006418)3.03522610
67amino acid activation (GO:0043038)3.03094980
68tRNA aminoacylation (GO:0043039)3.03094980
69ribosomal small subunit biogenesis (GO:0042274)3.02068008
70regulation of nuclear cell cycle DNA replication (GO:0033262)3.01853226
71translational elongation (GO:0006414)3.00968044
72DNA topological change (GO:0006265)3.00230584
73negative regulation of RNA splicing (GO:0033119)2.98492127
74CENP-A containing nucleosome assembly (GO:0034080)2.97152890
75metaphase plate congression (GO:0051310)2.96948063
76transcription elongation from RNA polymerase III promoter (GO:0006385)2.96738616
77termination of RNA polymerase III transcription (GO:0006386)2.96738616
78peptidyl-arginine methylation (GO:0018216)2.95991252
79peptidyl-arginine N-methylation (GO:0035246)2.95991252
80mitochondrial RNA metabolic process (GO:0000959)2.95896031
81negative regulation of mRNA metabolic process (GO:1903312)2.95618238
82folic acid metabolic process (GO:0046655)2.95446794
83tRNA modification (GO:0006400)2.94286120
84chromatin assembly (GO:0031497)2.93327159
85pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.93242011
86regulation of translational elongation (GO:0006448)2.93027294
87DNA conformation change (GO:0071103)2.92827947
88peptidyl-arginine omega-N-methylation (GO:0035247)2.92372391
89histone H2A acetylation (GO:0043968)2.91931447
90chromatin assembly or disassembly (GO:0006333)2.91518013
91chromatin remodeling at centromere (GO:0031055)2.90235958
92mismatch repair (GO:0006298)2.89951397
93DNA replication-dependent nucleosome assembly (GO:0006335)2.89318460
94DNA replication-dependent nucleosome organization (GO:0034723)2.89318460
95nuclear pore complex assembly (GO:0051292)2.87855044
96negative regulation of sister chromatid segregation (GO:0033046)2.87440871
97negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.87440871
98negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.87440871
99negative regulation of mitotic sister chromatid segregation (GO:0033048)2.87440871
100negative regulation of mitotic sister chromatid separation (GO:2000816)2.87440871
101RNA splicing, via transesterification reactions (GO:0000375)2.87304636
102meiotic chromosome segregation (GO:0045132)2.87257938
103nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.87195324
104ncRNA processing (GO:0034470)2.86310299
105termination of RNA polymerase II transcription (GO:0006369)2.86118428
106mRNA splicing, via spliceosome (GO:0000398)2.85990011
107RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.85990011
108histone arginine methylation (GO:0034969)2.84983819
109negative regulation of mRNA processing (GO:0050686)2.84776385
110telomere maintenance (GO:0000723)2.82767420
111transcription-coupled nucleotide-excision repair (GO:0006283)2.82682625
112telomere organization (GO:0032200)2.82665659
113regulation of double-strand break repair via homologous recombination (GO:0010569)2.81413741
114snRNA processing (GO:0016180)2.79159161
115DNA replication-independent nucleosome organization (GO:0034724)2.78382150
116DNA replication-independent nucleosome assembly (GO:0006336)2.78382150
117regulation of translational fidelity (GO:0006450)2.75820825
118regulation of helicase activity (GO:0051095)2.75340020
119snRNA metabolic process (GO:0016073)2.74520994
120* ribosomal large subunit biogenesis (GO:0042273)2.74342408
121mitotic sister chromatid segregation (GO:0000070)2.73130196
122mitochondrial DNA metabolic process (GO:0032042)2.71470906
123ncRNA metabolic process (GO:0034660)2.69823476
124spliceosomal tri-snRNP complex assembly (GO:0000244)2.69118694
125dosage compensation (GO:0007549)2.68647028
126* cellular component biogenesis (GO:0044085)2.65845746
127DNA-templated transcription, termination (GO:0006353)2.65808742
128rRNA methylation (GO:0031167)2.61737773
129RNA export from nucleus (GO:0006405)2.61280447
130negative regulation of chromosome segregation (GO:0051985)2.61245271
131establishment of chromosome localization (GO:0051303)2.61066276
132mitochondrial DNA replication (GO:0006264)2.60837190

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.10134282
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.30502555
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.61128582
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.22742586
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.19595670
6MYC_19079543_ChIP-ChIP_MESCs_Mouse3.09420863
7* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.85753520
8* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.83695405
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.78650470
10* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.69634470
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.58955083
12NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.57230315
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.56206531
14KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.53250459
15MYC_22102868_ChIP-Seq_BL_Human2.37632457
16GABP_17652178_ChIP-ChIP_JURKAT_Human2.33493696
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.28209196
18XRN2_22483619_ChIP-Seq_HELA_Human2.20085982
19NELFA_20434984_ChIP-Seq_ESCs_Mouse2.13712753
20CREB1_15753290_ChIP-ChIP_HEK293T_Human2.11083537
21* VDR_23849224_ChIP-Seq_CD4+_Human2.07231515
22ELF1_17652178_ChIP-ChIP_JURKAT_Human2.01460432
23FOXP3_21729870_ChIP-Seq_TREG_Human1.98955326
24* NOTCH1_21737748_ChIP-Seq_TLL_Human1.93181561
25SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.91971583
26* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.86364099
27CIITA_25753668_ChIP-Seq_RAJI_Human1.85688144
28E2F1_21310950_ChIP-Seq_MCF-7_Human1.84904857
29GABP_19822575_ChIP-Seq_HepG2_Human1.84599858
30* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.83870364
31DCP1A_22483619_ChIP-Seq_HELA_Human1.81305774
32MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.81216237
33CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.80905585
34NANOG_18555785_ChIP-Seq_MESCs_Mouse1.80475508
35EGR1_19374776_ChIP-ChIP_THP-1_Human1.80214631
36YY1_21170310_ChIP-Seq_MESCs_Mouse1.78369704
37MYCN_18555785_ChIP-Seq_MESCs_Mouse1.77587550
38TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.74967650
39TTF2_22483619_ChIP-Seq_HELA_Human1.72411495
40MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.71488057
41POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.69661855
42YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.64477937
43ZNF263_19887448_ChIP-Seq_K562_Human1.58628523
44HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.56319714
45TP63_19390658_ChIP-ChIP_HaCaT_Human1.55608156
46SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.53846968
47KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.52558863
48PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50444124
49SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.49952182
50FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.48933766
51VDR_21846776_ChIP-Seq_THP-1_Human1.47629627
52E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.46658614
53KDM5A_27292631_Chip-Seq_BREAST_Human1.46643709
54FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.41517149
55MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.41321552
56ZFX_18555785_ChIP-Seq_MESCs_Mouse1.40317919
57PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.37673922
58HOXB4_20404135_ChIP-ChIP_EML_Mouse1.36247461
59ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.35448757
60SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.34862308
61SRF_21415370_ChIP-Seq_HL-1_Mouse1.34739794
62ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.33230475
63CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.32843157
64AR_21909140_ChIP-Seq_LNCAP_Human1.32049093
65STAT3_1855785_ChIP-Seq_MESCs_Mouse1.31262126
66ELK1_19687146_ChIP-ChIP_HELA_Human1.24999163
67DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.23535263
68DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.22896554
69ERG_20887958_ChIP-Seq_HPC-7_Mouse1.22700049
70CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.21889038
71TFEB_21752829_ChIP-Seq_HELA_Human1.20210581
72CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.19964939
73POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.19744350
74KLF4_18555785_ChIP-Seq_MESCs_Mouse1.17592322
75POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.15951486
76TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.13618973
77SOX2_18555785_ChIP-Seq_MESCs_Mouse1.08528987
78SPI1_23547873_ChIP-Seq_NB4_Human1.07203984
79CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.06782837
80* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.06467058
81GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.06330367
82HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.06207322
83FOXP1_21924763_ChIP-Seq_HESCs_Human1.04912529
84* TET1_21451524_ChIP-Seq_MESCs_Mouse1.04505183
85CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.04363754
86E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.00763063
87IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.00683737
88CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.00496818
89CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.99736964
90ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.99435441
91TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.99115352
92KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.98823866
93KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.97855552
94BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.96775741
95CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.96593760
96TBX5_21415370_ChIP-Seq_HL-1_Mouse0.93823984
97SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.92422198
98SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.92349038
99P68_20966046_ChIP-Seq_HELA_Human0.92233197
100KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.91283089
101KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.91283089
102KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.91283089
103ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.89432147
104MYC_18940864_ChIP-ChIP_HL60_Human0.89023495
105RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.88708973
106SCL_19346495_ChIP-Seq_HPC-7_Human0.88584797
107PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.88545972
108CHD1_26751641_Chip-Seq_LNCaP_Human0.88157389
109SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.88077796
110MYB_26560356_Chip-Seq_TH1_Human0.87659126
111PADI4_21655091_ChIP-ChIP_MCF-7_Human0.87357540
112NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.86763986
113MAF_26560356_Chip-Seq_TH1_Human0.86651992
114NANOG_21062744_ChIP-ChIP_HESCs_Human0.84953277
115MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.84540650
116SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.83456610
117KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.82909576
118RACK7_27058665_Chip-Seq_MCF-7_Human0.82619262

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003111_abnormal_nucleus_morphology4.24408796
2* MP0003693_abnormal_embryo_hatching4.22423747
3MP0010094_abnormal_chromosome_stability4.21703901
4MP0008057_abnormal_DNA_replication4.12192666
5MP0008058_abnormal_DNA_repair3.57609769
6MP0004957_abnormal_blastocyst_morpholog3.57381138
7MP0003077_abnormal_cell_cycle3.52491083
8MP0002396_abnormal_hematopoietic_system3.20900163
9MP0008007_abnormal_cellular_replicative2.70762603
10MP0000490_abnormal_crypts_of2.20043306
11MP0003763_abnormal_thymus_physiology2.16945487
12MP0004233_abnormal_muscle_weight2.13973594
13MP0003786_premature_aging2.05271347
14MP0000350_abnormal_cell_proliferation1.98686687
15* MP0008932_abnormal_embryonic_tissue1.95679955
16MP0009333_abnormal_splenocyte_physiolog1.90779508
17MP0004808_abnormal_hematopoietic_stem1.86015624
18MP0006292_abnormal_olfactory_placode1.84210385
19MP0003123_paternal_imprinting1.83523639
20MP0000537_abnormal_urethra_morphology1.81649392
21MP0005397_hematopoietic_system_phenotyp1.80416455
22MP0001545_abnormal_hematopoietic_system1.80416455
23MP0001730_embryonic_growth_arrest1.78701756
24MP0009672_abnormal_birth_weight1.73811775
25MP0002132_abnormal_respiratory_system1.70370275
26MP0005075_abnormal_melanosome_morpholog1.68816053
27MP0006035_abnormal_mitochondrial_morpho1.66719214
28MP0010307_abnormal_tumor_latency1.65159845
29MP0004185_abnormal_adipocyte_glucose1.63815388
30MP0010352_gastrointestinal_tract_polyps1.61295149
31MP0002398_abnormal_bone_marrow1.60947568
32MP0001346_abnormal_lacrimal_gland1.59432119
33MP0001672_abnormal_embryogenesis/_devel1.57180213
34MP0005380_embryogenesis_phenotype1.57180213
35MP0000703_abnormal_thymus_morphology1.54414265
36MP0000313_abnormal_cell_death1.53254831
37MP0005377_hearing/vestibular/ear_phenot1.52197737
38MP0003878_abnormal_ear_physiology1.52197737
39MP0009278_abnormal_bone_marrow1.49160751
40MP0002722_abnormal_immune_system1.44765644
41MP0000689_abnormal_spleen_morphology1.44441412
42MP0002019_abnormal_tumor_incidence1.44217957
43MP0001697_abnormal_embryo_size1.43320676
44MP0003984_embryonic_growth_retardation1.39972495
45MP0003890_abnormal_embryonic-extraembry1.39686231
46MP0001661_extended_life_span1.38698304
47* MP0002080_prenatal_lethality1.36923194
48MP0002088_abnormal_embryonic_growth/wei1.36274532
49MP0003315_abnormal_perineum_morphology1.34960450
50MP0005451_abnormal_body_composition1.34660261
51MP0001835_abnormal_antigen_presentation1.33436871
52MP0000685_abnormal_immune_system1.32253717
53MP0005501_abnormal_skin_physiology1.31850340
54MP0003705_abnormal_hypodermis_morpholog1.31237316
55MP0002085_abnormal_embryonic_tissue1.31061614
56MP0002086_abnormal_extraembryonic_tissu1.26178902
57MP0009697_abnormal_copulation1.23633843
58MP0009053_abnormal_anal_canal1.23032650
59MP0008877_abnormal_DNA_methylation1.22514190
60MP0002084_abnormal_developmental_patter1.20765694
61MP0005671_abnormal_response_to1.20720985
62MP0002429_abnormal_blood_cell1.19995261
63MP0001188_hyperpigmentation1.18649746
64MP0001800_abnormal_humoral_immune1.18260756
65MP0005174_abnormal_tail_pigmentation1.15645944
66MP0001293_anophthalmia1.15305049
67MP0000716_abnormal_immune_system1.14576602
68MP0004197_abnormal_fetal_growth/weight/1.12267014
69MP0000015_abnormal_ear_pigmentation1.10046657
70MP0002697_abnormal_eye_size1.09838748
71MP0003718_maternal_effect1.09327757
72MP0010030_abnormal_orbit_morphology1.09137498
73MP0002160_abnormal_reproductive_system1.08028024
74MP0002405_respiratory_system_inflammati1.07440035
75MP0003937_abnormal_limbs/digits/tail_de1.05798621
76MP0006036_abnormal_mitochondrial_physio1.05564669
77MP0003941_abnormal_skin_development1.05162664
78MP0005083_abnormal_biliary_tract1.04331097
79MP0002420_abnormal_adaptive_immunity1.01616757
80MP0001819_abnormal_immune_cell1.00486373
81MP0001853_heart_inflammation0.99827449
82MP0002452_abnormal_antigen_presenting0.99186003
83MP0002249_abnormal_larynx_morphology0.99165465
84MP0004133_heterotaxia0.97941203
85MP0002796_impaired_skin_barrier0.96290127
86MP0002653_abnormal_ependyma_morphology0.95548009
87MP0005623_abnormal_meninges_morphology0.95034356
88MP0003121_genomic_imprinting0.94536672
89MP0000371_diluted_coat_color0.94529994
90MP0002723_abnormal_immune_serum0.93809333
91MP0008260_abnormal_autophagy0.92007280
92MP0000049_abnormal_middle_ear0.90471250
93MP0003943_abnormal_hepatobiliary_system0.90354867
94MP0003567_abnormal_fetal_cardiomyocyte0.88718032
95MP0002210_abnormal_sex_determination0.88250602
96MP0001929_abnormal_gametogenesis0.86833644
97MP0005076_abnormal_cell_differentiation0.86792184
98MP0002075_abnormal_coat/hair_pigmentati0.86583889
99MP0002877_abnormal_melanocyte_morpholog0.85489957
100MP0000858_altered_metastatic_potential0.84757426
101MP0002234_abnormal_pharynx_morphology0.83662027
102MP0000678_abnormal_parathyroid_gland0.83500328
103MP0003119_abnormal_digestive_system0.83266013
104MP0008789_abnormal_olfactory_epithelium0.82939416
105MP0003221_abnormal_cardiomyocyte_apopto0.82481494
106MP0003136_yellow_coat_color0.81876708
107MP0010155_abnormal_intestine_physiology0.81740330
108MP0009703_decreased_birth_body0.79622749
109MP0001119_abnormal_female_reproductive0.77838097
110MP0001849_ear_inflammation0.77467367
111MP0001915_intracranial_hemorrhage0.76550383
112MP0003861_abnormal_nervous_system0.75700657
113MP0002095_abnormal_skin_pigmentation0.75424808
114MP0005499_abnormal_olfactory_system0.75164584
115MP0005394_taste/olfaction_phenotype0.75164584
116MP0001145_abnormal_male_reproductive0.74880669
117MP0005220_abnormal_exocrine_pancreas0.73625021
118MP0005621_abnormal_cell_physiology0.73249504
119MP0001873_stomach_inflammation0.72689338
120MP0005384_cellular_phenotype0.72541214
121MP0002092_abnormal_eye_morphology0.72306509
122MP0003942_abnormal_urinary_system0.70390737
123MP0005025_abnormal_response_to0.70247863
124MP0002111_abnormal_tail_morphology0.68972438
125MP0000358_abnormal_cell_content/0.68868729
126MP0003806_abnormal_nucleotide_metabolis0.67350721
127MP0001790_abnormal_immune_system0.66530860
128MP0005387_immune_system_phenotype0.66530860
129MP0002114_abnormal_axial_skeleton0.66407813
130MP0001186_pigmentation_phenotype0.66216555
131MP0002938_white_spotting0.66146357
132MP0001286_abnormal_eye_development0.65808838
133MP0008995_early_reproductive_senescence0.63539749
134MP0000003_abnormal_adipose_tissue0.63327463
135MP0002161_abnormal_fertility/fecundity0.62640028
136MP0009785_altered_susceptibility_to0.62516755
137MP0000579_abnormal_nail_morphology0.62037423
138MP0005000_abnormal_immune_tolerance0.61929491
139MP0003385_abnormal_body_wall0.61767965
140MP0001764_abnormal_homeostasis0.61719150
141MP0005464_abnormal_platelet_physiology0.61601531
142MP0002089_abnormal_postnatal_growth/wei0.61201770
143MP0000653_abnormal_sex_gland0.61166228
144MP0003699_abnormal_female_reproductive0.61048981
145MP0000477_abnormal_intestine_morphology0.61040437
146MP0009250_abnormal_appendicular_skeleto0.60451882
147MP0000747_muscle_weakness0.59806189
148MP0003698_abnormal_male_reproductive0.58801948
149MP0000428_abnormal_craniofacial_morphol0.58500612

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.38801643
2Chromosomal breakage induced by crosslinking agents (HP:0003221)4.37360721
3Chromsome breakage (HP:0040012)4.10939330
4Selective tooth agenesis (HP:0001592)3.88068935
5Reticulocytopenia (HP:0001896)3.72488868
6Progressive muscle weakness (HP:0003323)3.51681708
7Aplastic anemia (HP:0001915)3.47776204
8Abnormal number of erythroid precursors (HP:0012131)3.47115733
9Abnormality of cells of the erythroid lineage (HP:0012130)3.43442365
10Abnormality of the ileum (HP:0001549)3.21743961
11Abnormality of the preputium (HP:0100587)3.15842058
12Ependymoma (HP:0002888)3.14094681
13Meckel diverticulum (HP:0002245)3.11685759
14Oral leukoplakia (HP:0002745)3.08610626
15Aplasia/Hypoplasia of the uvula (HP:0010293)3.03827782
16Myelodysplasia (HP:0002863)3.03666933
17Absent thumb (HP:0009777)2.98969978
18Abnormal number of incisors (HP:0011064)2.96597578
19Testicular atrophy (HP:0000029)2.95870816
20Broad distal phalanx of finger (HP:0009836)2.95647558
21Patellar aplasia (HP:0006443)2.95594000
22Abnormality of chromosome stability (HP:0003220)2.89608307
23Rough bone trabeculation (HP:0100670)2.83258422
24Breast hypoplasia (HP:0003187)2.81909820
25Aplasia/Hypoplasia of the sacrum (HP:0008517)2.81781541
26Premature graying of hair (HP:0002216)2.81011473
27IgM deficiency (HP:0002850)2.77432125
28Aplasia/Hypoplasia of the patella (HP:0006498)2.73624517
29Bone marrow hypocellularity (HP:0005528)2.71397452
30Progressive external ophthalmoplegia (HP:0000590)2.69674262
31Degeneration of anterior horn cells (HP:0002398)2.69038938
32Abnormality of the anterior horn cell (HP:0006802)2.69038938
33Vaginal fistula (HP:0004320)2.66789149
34Medulloblastoma (HP:0002885)2.59380516
35Thrombocytosis (HP:0001894)2.57078386
36Agnosia (HP:0010524)2.54208221
37Lymphoma (HP:0002665)2.52671614
38Pallor (HP:0000980)2.48477196
39Abnormality of DNA repair (HP:0003254)2.43989945
40Proximal placement of thumb (HP:0009623)2.43167092
41Absent radius (HP:0003974)2.40705286
42Hypoplasia of the capital femoral epiphysis (HP:0003090)2.35581982
43Duodenal stenosis (HP:0100867)2.35106728
44Small intestinal stenosis (HP:0012848)2.35106728
45Duplicated collecting system (HP:0000081)2.33703950
46Deviation of the thumb (HP:0009603)2.32300141
47Duplication of thumb phalanx (HP:0009942)2.31009004
48Ragged-red muscle fibers (HP:0003200)2.31006810
49Squamous cell carcinoma (HP:0002860)2.30657458
50Ulnar bowing (HP:0003031)2.28891215
51Basal cell carcinoma (HP:0002671)2.26646756
52Abnormality of the renal collecting system (HP:0004742)2.26085546
53Tracheoesophageal fistula (HP:0002575)2.25860356
54Abnormality of the labia minora (HP:0012880)2.23521514
55Impulsivity (HP:0100710)2.23098947
56Poikiloderma (HP:0001029)2.21550321
57Ectopic kidney (HP:0000086)2.20575237
58Prominent nose (HP:0000448)2.20229067
59Acute lymphatic leukemia (HP:0006721)2.20081734
60Cellular immunodeficiency (HP:0005374)2.19381292
61Absent forearm bone (HP:0003953)2.19288146
62Aplasia involving forearm bones (HP:0009822)2.19288146
63Abnormality of T cell physiology (HP:0011840)2.18778376
64Increased nuchal translucency (HP:0010880)2.18243359
65Premature ovarian failure (HP:0008209)2.18049009
66Reduced antithrombin III activity (HP:0001976)2.17689404
67Multiple enchondromatosis (HP:0005701)2.16941889
68Abnormality of the carotid arteries (HP:0005344)2.16155293
69Clubbing of toes (HP:0100760)2.13827137
70Colon cancer (HP:0003003)2.10277362
71Abnormality of cochlea (HP:0000375)2.09774782
72Microretrognathia (HP:0000308)2.09467132
73Macrocytic anemia (HP:0001972)2.07257278
74Intestinal fistula (HP:0100819)2.06920247
75Atresia of the external auditory canal (HP:0000413)2.05554969
76Muscle fiber atrophy (HP:0100295)2.05417201
77Cleft eyelid (HP:0000625)2.05235398
78Sloping forehead (HP:0000340)2.05094501
79Cerebral hypomyelination (HP:0006808)2.04662837
80Short thumb (HP:0009778)2.03718245
81Rib fusion (HP:0000902)2.03629971
82Carpal bone hypoplasia (HP:0001498)2.03219296
83Abnormal lung lobation (HP:0002101)2.02468329
84Panhypogammaglobulinemia (HP:0003139)2.02150887
85Supernumerary spleens (HP:0009799)2.01924047
86Increased serum lactate (HP:0002151)2.01699191
87Amaurosis fugax (HP:0100576)2.01114446
88Abnormality of T cells (HP:0002843)2.00571128
89IgG deficiency (HP:0004315)2.00093446
90Pancytopenia (HP:0001876)2.00072855
91Abnormality of glycolysis (HP:0004366)1.99022404
92Type 2 muscle fiber atrophy (HP:0003554)1.98747995
93Trismus (HP:0000211)1.98742406
94Abnormal umbilical cord blood vessels (HP:0011403)1.96156024
95Single umbilical artery (HP:0001195)1.96156024
96Abnormality of the fetal cardiovascular system (HP:0010948)1.96156024
97Type I transferrin isoform profile (HP:0003642)1.95964715
98Abnormal protein glycosylation (HP:0012346)1.95478524
99Abnormal glycosylation (HP:0012345)1.95478524
100Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.95478524
101Abnormal protein N-linked glycosylation (HP:0012347)1.95478524
102Neoplasm of the pancreas (HP:0002894)1.95083030
103Abnormality of the umbilical cord (HP:0010881)1.95061283
104Tongue fasciculations (HP:0001308)1.94985309
105Abnormality of the astrocytes (HP:0100707)1.94311207
106Astrocytoma (HP:0009592)1.94311207
107Abnormal trabecular bone morphology (HP:0100671)1.93974029
10811 pairs of ribs (HP:0000878)1.93931742
109Hypoplasia of the pons (HP:0012110)1.93075125
110Microvesicular hepatic steatosis (HP:0001414)1.93046205
111Rectovaginal fistula (HP:0000143)1.92990513
112Rectal fistula (HP:0100590)1.92990513
113Abnormality of the duodenum (HP:0002246)1.91705081
114Absent epiphyses (HP:0010577)1.88522867
115Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.88522867
116Glioma (HP:0009733)1.87784110
117Triphalangeal thumb (HP:0001199)1.86782200
118Cafe-au-lait spot (HP:0000957)1.84988642
119Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.84879757
120Abnormality of the phalanges of the hallux (HP:0010057)1.84569376
121Petechiae (HP:0000967)1.83307202
122Preauricular skin tag (HP:0000384)1.82398817
123Septate vagina (HP:0001153)1.82121585
124Pustule (HP:0200039)1.80668365
125Abnormal delayed hypersensitivity skin test (HP:0002963)1.80301696
126Capillary hemangiomas (HP:0005306)1.80183745
127Sensory axonal neuropathy (HP:0003390)1.79825938
128Leukopenia (HP:0001882)1.76394881
129Abnormality of homocysteine metabolism (HP:0010919)1.76092174
130Homocystinuria (HP:0002156)1.76092174
131Urethral obstruction (HP:0000796)1.75895330
132Choanal atresia (HP:0000453)1.75772553
133Hyperacusis (HP:0010780)1.74838400
134Slender long bone (HP:0003100)1.74568279
135Facial hemangioma (HP:0000329)1.74080244
136Optic nerve coloboma (HP:0000588)1.73928654
137Neoplasm of the oral cavity (HP:0100649)1.73400764
138Secondary amenorrhea (HP:0000869)1.72998625
139Abnormality of the pons (HP:0007361)1.72275753
140Pulmonary fibrosis (HP:0002206)1.71665534
141Horseshoe kidney (HP:0000085)1.71617590
142Acute myeloid leukemia (HP:0004808)1.70955865
143Rhabdomyosarcoma (HP:0002859)1.70681300
144Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.70632867
145IgA deficiency (HP:0002720)1.69872348
146Ureteral duplication (HP:0000073)1.69193758
147Premature skin wrinkling (HP:0100678)1.67344273
148Sparse lateral eyebrow (HP:0005338)1.66171311

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB13.51724600
2SMG13.28189058
3WEE13.16052113
4CDC72.90323839
5TSSK62.85176023
6MAP4K12.74253883
7VRK22.65063859
8TRIB32.38617316
9EEF2K2.27245557
10EIF2AK12.18794636
11NME22.17466401
12SRPK12.09425067
13NEK22.08687324
14CDK72.05923657
15CDK122.01865284
16TTK1.96137175
17ACVR1B1.94524518
18PIM21.92870644
19MKNK21.88692976
20PASK1.86313856
21PBK1.86116134
22ATR1.85597711
23RPS6KB21.81067767
24PLK11.74222272
25MKNK11.66792021
26NME11.61652897
27TAF11.60965028
28DYRK31.58861318
29TXK1.55674710
30CDK41.53908366
31TAOK21.53349700
32MAP3K111.49272766
33STK161.43805252
34FLT31.40535122
35PLK41.39968879
36AURKB1.39107211
37STK101.38038043
38CAMK1D1.35752412
39MAP3K101.35611660
40PIM11.34341074
41RAF11.31850777
42CHEK21.28660466
43RPS6KA41.28509809
44EPHA21.25108438
45VRK11.21088988
46CHEK11.20146074
47ZAP701.18912647
48TGFBR11.12270422
49AKT31.11837427
50BTK1.11333250
51TLK11.11225556
52MAP3K81.10275176
53ZAK1.07568693
54EIF2AK31.06952172
55JAK31.06004628
56MST1R1.01585958
57ALK1.00230791
58CAMK1G1.00175166
59NEK10.98028484
60BRD40.97712642
61CCNB10.97482227
62CDK80.97119638
63PDK20.97109487
64STK40.96173872
65BRSK20.91318529
66BRAF0.89832942
67AURKA0.88485085
68PLK30.87684497
69CDK20.87036783
70MAP2K30.86519321
71CDK190.85544587
72EIF2AK20.84616051
73ATM0.82355449
74KIT0.82262528
75BLK0.81500635
76IKBKB0.78113884
77CDK90.76826827
78TEC0.75801477
79TESK20.75420502
80SCYL20.73136108
81DAPK10.70376647
82MATK0.69925064
83ARAF0.69880460
84CSNK2A20.69237465
85GRK60.68876671
86PRKCI0.68213723
87SIK10.67850176
88PRKD30.67373619
89ICK0.66964202
90PAK40.65080697
91BCKDK0.65072824
92CSNK2A10.62973261
93IRAK20.62829288
94KDR0.62126867
95PRPF4B0.61734666
96PKN20.61383877
97BRSK10.60836478
98STK30.60730215
99CDK60.60517717
100CHUK0.60039045
101KSR20.58207406
102NUAK10.55058436
103CSF1R0.54932429
104RPS6KC10.54667252
105RPS6KL10.54667252
106IRAK40.54252476
107AKT20.53264177
108YES10.52623341
109RPS6KA60.52608479
110CSNK1G30.52496836
111IRAK30.52287852
112MTOR0.52223080
113CDK10.51766361
114SYK0.50199965
115TNK20.49993647
116LYN0.49825997
117SIK30.49082222
118PAK10.48552098
119CLK10.46831582
120TAOK10.45789050
121CDK11A0.43020937
122RPS6KA50.42779572
123MAPKAPK50.42554919
124RPS6KB10.41662142
125CSNK1A1L0.41011194
126MAPK110.40427392
127CSNK1G10.39751945
128MELK0.37538289
129ILK0.36878522
130CDK150.35952042
131RPS6KA10.35000308
132PRKDC0.32247288
133CDK180.31883181

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.60029192
2Mismatch repair_Homo sapiens_hsa034304.07677747
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.82464028
4Base excision repair_Homo sapiens_hsa034103.37376347
5Spliceosome_Homo sapiens_hsa030403.15586389
6One carbon pool by folate_Homo sapiens_hsa006702.99903931
7Ribosome_Homo sapiens_hsa030102.96548446
8Homologous recombination_Homo sapiens_hsa034402.88562869
9RNA polymerase_Homo sapiens_hsa030202.84237045
10RNA transport_Homo sapiens_hsa030132.82770100
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.63622413
12Nucleotide excision repair_Homo sapiens_hsa034202.55225084
13Cell cycle_Homo sapiens_hsa041102.34630685
14Fanconi anemia pathway_Homo sapiens_hsa034602.31324740
15Proteasome_Homo sapiens_hsa030502.26073738
16Pyrimidine metabolism_Homo sapiens_hsa002402.22006725
17Non-homologous end-joining_Homo sapiens_hsa034501.75313859
18mRNA surveillance pathway_Homo sapiens_hsa030151.71894827
19RNA degradation_Homo sapiens_hsa030181.70111760
20p53 signaling pathway_Homo sapiens_hsa041151.65790572
21Basal transcription factors_Homo sapiens_hsa030221.58965627
22Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.55939089
23Primary immunodeficiency_Homo sapiens_hsa053401.49465123
24Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.46974919
25Herpes simplex infection_Homo sapiens_hsa051681.34485555
26Sulfur relay system_Homo sapiens_hsa041221.26748169
27Purine metabolism_Homo sapiens_hsa002301.20061542
28Epstein-Barr virus infection_Homo sapiens_hsa051691.19182050
29Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.13835542
30Carbon metabolism_Homo sapiens_hsa012001.12624984
31Pyruvate metabolism_Homo sapiens_hsa006201.11225711
32Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.04702932
33Folate biosynthesis_Homo sapiens_hsa007901.03976589
34Antigen processing and presentation_Homo sapiens_hsa046121.03318742
35NF-kappa B signaling pathway_Homo sapiens_hsa040640.99433969
36Measles_Homo sapiens_hsa051620.96352223
37Viral carcinogenesis_Homo sapiens_hsa052030.95641518
38Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.94174015
39Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.87362748
40Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.86895850
41Legionellosis_Homo sapiens_hsa051340.86680989
42Alcoholism_Homo sapiens_hsa050340.86555126
43Pentose phosphate pathway_Homo sapiens_hsa000300.84908778
44HTLV-I infection_Homo sapiens_hsa051660.84787792
45Acute myeloid leukemia_Homo sapiens_hsa052210.82413781
46Huntingtons disease_Homo sapiens_hsa050160.81705989
47Transcriptional misregulation in cancer_Homo sapiens_hsa052020.81194839
48Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.79798460
49Intestinal immune network for IgA production_Homo sapiens_hsa046720.79686643
50Steroid biosynthesis_Homo sapiens_hsa001000.77253047
51Vitamin B6 metabolism_Homo sapiens_hsa007500.76303617
52Biosynthesis of amino acids_Homo sapiens_hsa012300.74877977
53Notch signaling pathway_Homo sapiens_hsa043300.74306140
54Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.73859535
55Cysteine and methionine metabolism_Homo sapiens_hsa002700.71648397
56Apoptosis_Homo sapiens_hsa042100.68464721
57Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.67105496
58Systemic lupus erythematosus_Homo sapiens_hsa053220.66957955
59Hematopoietic cell lineage_Homo sapiens_hsa046400.66442594
60Drug metabolism - other enzymes_Homo sapiens_hsa009830.64860461
61Parkinsons disease_Homo sapiens_hsa050120.64331520
62RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.63436397
63Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.60614950
64Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.59386740
65Hepatitis B_Homo sapiens_hsa051610.57936394
66Small cell lung cancer_Homo sapiens_hsa052220.57362987
67Influenza A_Homo sapiens_hsa051640.54568755
68Cyanoamino acid metabolism_Homo sapiens_hsa004600.54190224
69Selenocompound metabolism_Homo sapiens_hsa004500.54147125
70Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.53421322
71MicroRNAs in cancer_Homo sapiens_hsa052060.52594709
72Shigellosis_Homo sapiens_hsa051310.52329295
73Allograft rejection_Homo sapiens_hsa053300.51236775
74Fructose and mannose metabolism_Homo sapiens_hsa000510.50490090
75Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.48720258
76Arginine and proline metabolism_Homo sapiens_hsa003300.48659412
77Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.48320728
78Fatty acid elongation_Homo sapiens_hsa000620.48028517
79Colorectal cancer_Homo sapiens_hsa052100.46965004
80mTOR signaling pathway_Homo sapiens_hsa041500.46452848
81Oocyte meiosis_Homo sapiens_hsa041140.46382968
82Jak-STAT signaling pathway_Homo sapiens_hsa046300.45841487
83Oxidative phosphorylation_Homo sapiens_hsa001900.45275717
84Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.45180566
85Thyroid cancer_Homo sapiens_hsa052160.44860361
86Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.44782314
87Metabolic pathways_Homo sapiens_hsa011000.44574269
88Chronic myeloid leukemia_Homo sapiens_hsa052200.42923936
89Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.42179339
90NOD-like receptor signaling pathway_Homo sapiens_hsa046210.42165035
91Leishmaniasis_Homo sapiens_hsa051400.42102915
92HIF-1 signaling pathway_Homo sapiens_hsa040660.41145149
93Arginine biosynthesis_Homo sapiens_hsa002200.40786946
94Basal cell carcinoma_Homo sapiens_hsa052170.40364275
95Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.39683571
96Non-small cell lung cancer_Homo sapiens_hsa052230.38209746
97Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.36625634
98Viral myocarditis_Homo sapiens_hsa054160.33886348
99Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.33613412
100Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.33240465
101Galactose metabolism_Homo sapiens_hsa000520.32852054
102Hippo signaling pathway_Homo sapiens_hsa043900.32419049
103T cell receptor signaling pathway_Homo sapiens_hsa046600.31829957
104B cell receptor signaling pathway_Homo sapiens_hsa046620.31666187
105Pancreatic cancer_Homo sapiens_hsa052120.31593337
106Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.30069433
107TGF-beta signaling pathway_Homo sapiens_hsa043500.29644548
108N-Glycan biosynthesis_Homo sapiens_hsa005100.28972288
109Glutathione metabolism_Homo sapiens_hsa004800.28895878
110Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.28567393
111Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.27744164
112Prostate cancer_Homo sapiens_hsa052150.27623758
113Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.27450815
114Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.26599340
115Hedgehog signaling pathway_Homo sapiens_hsa043400.26515712
116Vitamin digestion and absorption_Homo sapiens_hsa049770.25630245
117Wnt signaling pathway_Homo sapiens_hsa043100.23638416
118Pathways in cancer_Homo sapiens_hsa052000.23245561
119Endometrial cancer_Homo sapiens_hsa052130.22571827
120Toll-like receptor signaling pathway_Homo sapiens_hsa046200.22526377
121Graft-versus-host disease_Homo sapiens_hsa053320.22201536
122Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.21418635
123Central carbon metabolism in cancer_Homo sapiens_hsa052300.21414650
124Alzheimers disease_Homo sapiens_hsa050100.21147501
125AMPK signaling pathway_Homo sapiens_hsa041520.21101052
126Asthma_Homo sapiens_hsa053100.20786009
127Autoimmune thyroid disease_Homo sapiens_hsa053200.19441623
128Lysine degradation_Homo sapiens_hsa003100.18883088
129Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.18545168
130TNF signaling pathway_Homo sapiens_hsa046680.18022336
131Melanoma_Homo sapiens_hsa052180.17803919
132Regulation of autophagy_Homo sapiens_hsa041400.17750557
133Fatty acid biosynthesis_Homo sapiens_hsa000610.17442744
134Bladder cancer_Homo sapiens_hsa052190.16038874
135Circadian rhythm_Homo sapiens_hsa047100.15850498
1362-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.15269413
137Longevity regulating pathway - mammal_Homo sapiens_hsa042110.15175310

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