NKIRAS1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuronal action potential propagation (GO:0019227)5.20924754
2neuron cell-cell adhesion (GO:0007158)5.01873344
3synaptic vesicle exocytosis (GO:0016079)4.77431502
4presynaptic membrane assembly (GO:0097105)4.67522640
5vocalization behavior (GO:0071625)4.47041072
6presynaptic membrane organization (GO:0097090)4.46670926
7protein localization to synapse (GO:0035418)4.26611081
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.23585611
9regulation of short-term neuronal synaptic plasticity (GO:0048172)4.21338866
10mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.16476733
11positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.10459556
12glutamate secretion (GO:0014047)4.08859323
13negative regulation of synaptic transmission, GABAergic (GO:0032229)4.00686809
14regulation of synaptic vesicle exocytosis (GO:2000300)3.99701409
15gamma-aminobutyric acid signaling pathway (GO:0007214)3.92536710
16regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.88091504
17neuron-neuron synaptic transmission (GO:0007270)3.83924499
18ionotropic glutamate receptor signaling pathway (GO:0035235)3.81214198
19regulation of glutamate receptor signaling pathway (GO:1900449)3.73490711
20chaperone-mediated protein transport (GO:0072321)3.72720920
21glutamate receptor signaling pathway (GO:0007215)3.69014675
22synaptic transmission, glutamatergic (GO:0035249)3.62314029
23positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.61321948
24postsynaptic membrane organization (GO:0001941)3.59106874
25regulation of synaptic vesicle transport (GO:1902803)3.57431467
26positive regulation of mitochondrial fission (GO:0090141)3.54420916
27neurotransmitter secretion (GO:0007269)3.54277992
28transmission of nerve impulse (GO:0019226)3.48308268
29mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.47989223
30pyrimidine nucleobase catabolic process (GO:0006208)3.42118444
31ATP hydrolysis coupled proton transport (GO:0015991)3.38538418
32energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.38538418
33neurotransmitter-gated ion channel clustering (GO:0072578)3.37013881
34energy coupled proton transport, down electrochemical gradient (GO:0015985)3.31452665
35ATP synthesis coupled proton transport (GO:0015986)3.31452665
36long-chain fatty acid biosynthetic process (GO:0042759)3.31060424
37respiratory electron transport chain (GO:0022904)3.30745640
38negative regulation of neurotransmitter transport (GO:0051589)3.28235851
39startle response (GO:0001964)3.25589554
40synaptic vesicle maturation (GO:0016188)3.25337003
41behavioral response to cocaine (GO:0048148)3.23894103
42neurotransmitter transport (GO:0006836)3.23548882
43gamma-aminobutyric acid transport (GO:0015812)3.23161206
44neuron recognition (GO:0008038)3.22982208
45electron transport chain (GO:0022900)3.22721077
46membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.19427046
47regulation of excitatory postsynaptic membrane potential (GO:0060079)3.18369954
48nucleobase catabolic process (GO:0046113)3.17961633
49positive regulation of synapse assembly (GO:0051965)3.17081985
50regulation of glutamate secretion (GO:0014048)3.16800375
51transferrin transport (GO:0033572)3.14186083
52positive regulation of membrane potential (GO:0045838)3.12889523
53regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.12164718
54regulation of hexokinase activity (GO:1903299)3.10158364
55regulation of glucokinase activity (GO:0033131)3.10158364
56neuromuscular process controlling posture (GO:0050884)3.09191424
57regulation of postsynaptic membrane potential (GO:0060078)3.08106671
58proline transport (GO:0015824)3.07980613
59response to histamine (GO:0034776)3.06542904
60long-term synaptic potentiation (GO:0060291)3.05724029
61regulation of neuronal synaptic plasticity (GO:0048168)3.04011096
62synaptic vesicle docking involved in exocytosis (GO:0016081)3.03959793
63righting reflex (GO:0060013)3.03746962
64G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.01698765
65negative regulation of dendrite morphogenesis (GO:0050774)2.98553360
66regulation of long-term neuronal synaptic plasticity (GO:0048169)2.98133158
67locomotory exploration behavior (GO:0035641)2.97869654
68regulation of vesicle fusion (GO:0031338)2.97659991
69regulation of dopamine metabolic process (GO:0042053)2.96728674
70regulation of catecholamine metabolic process (GO:0042069)2.96728674
71neurofilament cytoskeleton organization (GO:0060052)2.96040181
72adult walking behavior (GO:0007628)2.95383787
73regulation of neurotransmitter levels (GO:0001505)2.94632894
74regulation of neurotransmitter secretion (GO:0046928)2.94585561
75regulation of synapse structural plasticity (GO:0051823)2.93794096
76ferric iron transport (GO:0015682)2.92481527
77trivalent inorganic cation transport (GO:0072512)2.92481527
78long-term memory (GO:0007616)2.90434462
79neurotransmitter uptake (GO:0001504)2.89487253
80regulation of synaptic transmission, glutamatergic (GO:0051966)2.87665438
81serotonin receptor signaling pathway (GO:0007210)2.86934668
82protein localization to cilium (GO:0061512)2.85021630
83synaptic vesicle endocytosis (GO:0048488)2.84540029
84axon ensheathment in central nervous system (GO:0032291)2.84063813
85central nervous system myelination (GO:0022010)2.84063813
86exploration behavior (GO:0035640)2.82948786
87negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.82236185
88cerebellar granule cell differentiation (GO:0021707)2.82213639
89detection of calcium ion (GO:0005513)2.81874565
90protein polyglutamylation (GO:0018095)2.81694833
91regulation of neurotransmitter transport (GO:0051588)2.79871391
92regulation of voltage-gated calcium channel activity (GO:1901385)2.79780551
93regulation of protein kinase A signaling (GO:0010738)2.79491893
94striatum development (GO:0021756)2.78752872
95synaptic transmission, dopaminergic (GO:0001963)2.77729895
96dopamine transport (GO:0015872)2.76216771
97synaptic transmission (GO:0007268)2.76000574
98regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.74703526
99C4-dicarboxylate transport (GO:0015740)2.74693251
100positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.74676230
101membrane depolarization (GO:0051899)2.74169811
102regulation of synaptic plasticity (GO:0048167)2.73247945
103calcium-mediated signaling using intracellular calcium source (GO:0035584)2.72689088
104nonmotile primary cilium assembly (GO:0035058)2.72537665
105brain morphogenesis (GO:0048854)2.71887587
106positive regulation of meiosis (GO:0045836)2.71675457
107glycosphingolipid biosynthetic process (GO:0006688)2.70539774
108positive regulation of synaptic transmission, GABAergic (GO:0032230)2.70356236
109membrane hyperpolarization (GO:0060081)2.69094950
110learning (GO:0007612)2.68160334
111establishment of synaptic vesicle localization (GO:0097480)2.67601654
112synaptic vesicle transport (GO:0048489)2.67601654
113response to cocaine (GO:0042220)2.67506420
114positive regulation of neurotransmitter transport (GO:0051590)2.66167315
115cellular sodium ion homeostasis (GO:0006883)2.63949830
116regulation of cilium movement (GO:0003352)2.59624353
117dendritic spine morphogenesis (GO:0060997)2.58214108
118retinal cone cell development (GO:0046549)2.56694685
119negative regulation of cytosolic calcium ion concentration (GO:0051481)2.54028432
120piRNA metabolic process (GO:0034587)2.53038623
121regulation of neurotransmitter uptake (GO:0051580)2.52911310
122cellular potassium ion homeostasis (GO:0030007)2.51992890
123positive regulation of meiotic cell cycle (GO:0051446)2.49525158
124water-soluble vitamin biosynthetic process (GO:0042364)2.47960488
125respiratory chain complex IV assembly (GO:0008535)2.47693005
126regulation of meiosis I (GO:0060631)2.46916316
127axonal fasciculation (GO:0007413)2.46636164
128calcium ion-dependent exocytosis (GO:0017156)2.45517642
129protein complex biogenesis (GO:0070271)2.45403043
130regulation of calcium ion-dependent exocytosis (GO:0017158)2.45231878
131response to pheromone (GO:0019236)2.42578320
132neuromuscular synaptic transmission (GO:0007274)2.41351111
133regulation of dendritic spine morphogenesis (GO:0061001)2.40073482
134behavioral response to nicotine (GO:0035095)2.39950707
135chemosensory behavior (GO:0007635)2.39621080
136positive regulation of amino acid transport (GO:0051957)2.38495228
137membrane depolarization during action potential (GO:0086010)2.38281567
138proteasome assembly (GO:0043248)2.36899702
139intraciliary transport (GO:0042073)2.35694305
140regulation of type B pancreatic cell apoptotic process (GO:2000674)2.35291793
141negative regulation of dendrite development (GO:2000171)2.34824016
142regulation of dendritic spine development (GO:0060998)2.34022514
143regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.33937664
144positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.31999666
145ADP metabolic process (GO:0046031)2.31162121
146regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.30110425
147cellular ketone body metabolic process (GO:0046950)2.29080353
148regulation of cell communication by electrical coupling (GO:0010649)2.28575893
149response to nitrosative stress (GO:0051409)2.27812655
150positive regulation of amine transport (GO:0051954)2.27379233
151synapse assembly (GO:0007416)2.26999966
152auditory behavior (GO:0031223)2.26561299
153negative regulation of membrane potential (GO:0045837)2.26147836
154regulation of microtubule-based movement (GO:0060632)2.25270801
155anterograde axon cargo transport (GO:0008089)2.24855839
156mitochondrial respiratory chain complex assembly (GO:0033108)2.24355966

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.12114209
2GBX2_23144817_ChIP-Seq_PC3_Human4.30108003
3TAF15_26573619_Chip-Seq_HEK293_Human3.12153747
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.86767544
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.82807163
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.71756744
7EZH2_27304074_Chip-Seq_ESCs_Mouse2.39108567
8ZFP57_27257070_Chip-Seq_ESCs_Mouse2.38990085
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.37867634
10REST_21632747_ChIP-Seq_MESCs_Mouse2.32791400
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.28207752
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.27540435
13RNF2_18974828_ChIP-Seq_MESCs_Mouse2.27540435
14TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.24296191
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.23358565
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.23124631
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.18776785
18CTBP1_25329375_ChIP-Seq_LNCAP_Human2.16782624
19GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.16702479
20CTBP2_25329375_ChIP-Seq_LNCAP_Human2.16336351
21SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.11113628
22MTF2_20144788_ChIP-Seq_MESCs_Mouse2.09286894
23BMI1_23680149_ChIP-Seq_NPCS_Mouse2.05567901
24* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.90972743
25P300_19829295_ChIP-Seq_ESCs_Human1.87816690
26NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.86689682
27EZH2_27294783_Chip-Seq_ESCs_Mouse1.86248890
28SUZ12_27294783_Chip-Seq_ESCs_Mouse1.85635641
29VDR_22108803_ChIP-Seq_LS180_Human1.85070227
30REST_18959480_ChIP-ChIP_MESCs_Mouse1.84316200
31CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.82044355
32RNF2_27304074_Chip-Seq_ESCs_Mouse1.77849057
33SMAD4_21799915_ChIP-Seq_A2780_Human1.77227089
34AR_21572438_ChIP-Seq_LNCaP_Human1.76859535
35IGF1R_20145208_ChIP-Seq_DFB_Human1.68948472
36CBX2_27304074_Chip-Seq_ESCs_Mouse1.68272526
37GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.67686237
38FUS_26573619_Chip-Seq_HEK293_Human1.67318457
39SALL1_21062744_ChIP-ChIP_HESCs_Human1.66749686
40HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.64402268
41PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.60851814
42RARB_27405468_Chip-Seq_BRAIN_Mouse1.59099506
43KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.57698654
44SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.54360958
45SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.52324438
46NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.52215650
47RNF2_27304074_Chip-Seq_NSC_Mouse1.51169094
48PIAS1_25552417_ChIP-Seq_VCAP_Human1.50573723
49E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.50358497
50FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.50328247
51DROSHA_22980978_ChIP-Seq_HELA_Human1.48279953
52SMAD3_21741376_ChIP-Seq_EPCs_Human1.47559867
53PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.47178574
54TOP2B_26459242_ChIP-Seq_MCF-7_Human1.46979809
55OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.44502456
56HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.43573144
57ER_23166858_ChIP-Seq_MCF-7_Human1.40069978
58FLI1_27457419_Chip-Seq_LIVER_Mouse1.39561634
59IKZF1_21737484_ChIP-ChIP_HCT116_Human1.39346285
60SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34250663
61NANOG_18555785_Chip-Seq_ESCs_Mouse1.34165799
62PCGF2_27294783_Chip-Seq_ESCs_Mouse1.33586240
63* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.30213113
64AR_25329375_ChIP-Seq_VCAP_Human1.29501068
65TP53_22573176_ChIP-Seq_HFKS_Human1.28590545
66CBP_20019798_ChIP-Seq_JUKART_Human1.28510141
67IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.28510141
68RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.26211304
69TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.25528941
70STAT3_23295773_ChIP-Seq_U87_Human1.23430967
71RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.22411479
72EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.21960701
73NR3C1_23031785_ChIP-Seq_PC12_Mouse1.21439337
74MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.19152516
75ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.18886207
76TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.17705707
77KLF5_20875108_ChIP-Seq_MESCs_Mouse1.17357174
78P53_22387025_ChIP-Seq_ESCs_Mouse1.16637925
79GABP_17652178_ChIP-ChIP_JURKAT_Human1.15933541
80AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.14928468
81E2F1_18555785_Chip-Seq_ESCs_Mouse1.14703100
82TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.14653779
83PRDM14_20953172_ChIP-Seq_ESCs_Human1.14538593
84NR3C1_21868756_ChIP-Seq_MCF10A_Human1.14112634
85TCF4_23295773_ChIP-Seq_U87_Human1.13838004
86RUNX2_22187159_ChIP-Seq_PCA_Human1.13722690
87SOX2_19829295_ChIP-Seq_ESCs_Human1.13501277
88NANOG_19829295_ChIP-Seq_ESCs_Human1.13501277
89* JUN_21703547_ChIP-Seq_K562_Human1.11916478
90CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11773002
91CMYC_18555785_Chip-Seq_ESCs_Mouse1.11281196
92SOX2_21211035_ChIP-Seq_LN229_Gbm1.11242003
93EZH2_27294783_Chip-Seq_NPCs_Mouse1.11120452
94SUZ12_18555785_Chip-Seq_ESCs_Mouse1.10261976
95SUZ12_27294783_Chip-Seq_NPCs_Mouse1.09944087
96SMAD_19615063_ChIP-ChIP_OVARY_Human1.09688401
97MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.08726622
98EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.07814600
99SMAD4_21741376_ChIP-Seq_EPCs_Human1.07693635
100ZNF274_21170338_ChIP-Seq_K562_Hela1.07191110
101CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.06425000
102SOX2_18555785_Chip-Seq_ESCs_Mouse1.06249338
103TCF4_22108803_ChIP-Seq_LS180_Human1.06058998
104FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.05544638
105P53_22127205_ChIP-Seq_FIBROBLAST_Human1.05532017
106MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05210180
107STAT3_18555785_Chip-Seq_ESCs_Mouse1.04963590
108CDX2_19796622_ChIP-Seq_MESCs_Mouse1.04871732
109P300_18555785_Chip-Seq_ESCs_Mouse1.04417892
110FLI1_21867929_ChIP-Seq_TH2_Mouse1.04196901
111RBPJ_22232070_ChIP-Seq_NCS_Mouse1.03989307
112PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.03331860
113ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.03274963
114EST1_17652178_ChIP-ChIP_JURKAT_Human1.02867893
115RUNX1_27457419_Chip-Seq_LIVER_Mouse1.01030375
116TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99735116
117KDM2B_26808549_Chip-Seq_REH_Human0.99731647
118GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.99669335
119EWS_26573619_Chip-Seq_HEK293_Human0.99325692
120MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.97570230
121BCAT_22108803_ChIP-Seq_LS180_Human0.97295930
122TAL1_26923725_Chip-Seq_HPCs_Mouse0.96803938
123PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.96414162
124HTT_18923047_ChIP-ChIP_STHdh_Human0.95520581
125NMYC_18555785_Chip-Seq_ESCs_Mouse0.95513889

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.62179862
2MP0004859_abnormal_synaptic_plasticity4.13074103
3MP0003635_abnormal_synaptic_transmissio3.36536639
4MP0004270_analgesia3.21241760
5MP0009046_muscle_twitch3.19705382
6MP0009745_abnormal_behavioral_response3.18634091
7MP0002064_seizures3.02227067
8MP0001968_abnormal_touch/_nociception2.92719727
9MP0002272_abnormal_nervous_system2.77610552
10MP0002063_abnormal_learning/memory/cond2.68972804
11MP0006276_abnormal_autonomic_nervous2.65397145
12MP0001529_abnormal_vocalization2.63800117
13MP0002572_abnormal_emotion/affect_behav2.62753144
14MP0001486_abnormal_startle_reflex2.61915704
15MP0002736_abnormal_nociception_after2.59157060
16MP0002734_abnormal_mechanical_nocicepti2.49054379
17MP0002735_abnormal_chemical_nociception2.38740834
18MP0001440_abnormal_grooming_behavior2.31525622
19MP0002822_catalepsy2.27714510
20MP0001501_abnormal_sleep_pattern2.20781703
21MP0001905_abnormal_dopamine_level2.20107251
22MP0004142_abnormal_muscle_tone2.16461812
23MP0002067_abnormal_sensory_capabilities2.12857964
24MP0005423_abnormal_somatic_nervous2.09741852
25MP0008877_abnormal_DNA_methylation2.00707956
26MP0005646_abnormal_pituitary_gland1.95428320
27MP0002733_abnormal_thermal_nociception1.94002041
28MP0001970_abnormal_pain_threshold1.93755851
29MP0001188_hyperpigmentation1.86380038
30MP0001984_abnormal_olfaction1.77327086
31MP0000569_abnormal_digit_pigmentation1.76860695
32MP0005386_behavior/neurological_phenoty1.76090567
33MP0004924_abnormal_behavior1.76090567
34MP0003195_calcinosis1.76021338
35MP0002837_dystrophic_cardiac_calcinosis1.72987164
36MP0000778_abnormal_nervous_system1.67264460
37MP0002557_abnormal_social/conspecific_i1.62115550
38MP0002184_abnormal_innervation1.60977505
39MP0003329_amyloid_beta_deposits1.43751583
40MP0002876_abnormal_thyroid_physiology1.43067720
41MP0008569_lethality_at_weaning1.41008986
42MP0005645_abnormal_hypothalamus_physiol1.39605046
43MP0003879_abnormal_hair_cell1.38163176
44MP0004742_abnormal_vestibular_system1.37890284
45MP0005253_abnormal_eye_physiology1.36286557
46MP0002066_abnormal_motor_capabilities/c1.35472122
47MP0010386_abnormal_urinary_bladder1.35362606
48MP0004145_abnormal_muscle_electrophysio1.31958151
49MP0000955_abnormal_spinal_cord1.31779552
50MP0002882_abnormal_neuron_morphology1.29856564
51MP0001502_abnormal_circadian_rhythm1.29645932
52MP0003787_abnormal_imprinting1.28084827
53MP0005551_abnormal_eye_electrophysiolog1.26094509
54MP0003136_yellow_coat_color1.25115264
55MP0002229_neurodegeneration1.22815957
56MP0005409_darkened_coat_color1.21167313
57MP0003122_maternal_imprinting1.20157896
58MP0001986_abnormal_taste_sensitivity1.19955021
59MP0003121_genomic_imprinting1.19168415
60MP0001963_abnormal_hearing_physiology1.18011944
61MP0001485_abnormal_pinna_reflex1.14764972
62MP0000920_abnormal_myelination1.13282440
63MP0004811_abnormal_neuron_physiology1.12199407
64MP0005171_absent_coat_pigmentation1.11216530
65MP0001299_abnormal_eye_distance/1.09604374
66MP0002638_abnormal_pupillary_reflex1.09424621
67MP0005379_endocrine/exocrine_gland_phen1.07360638
68MP0000751_myopathy1.05474255
69MP0000372_irregular_coat_pigmentation1.00805257
70MP0005187_abnormal_penis_morphology0.97601515
71MP0002752_abnormal_somatic_nervous0.97357889
72MP0004885_abnormal_endolymph0.96481459
73MP0002090_abnormal_vision0.96351154
74MP0003633_abnormal_nervous_system0.95054159
75MP0008260_abnormal_autophagy0.93458013
76MP0002909_abnormal_adrenal_gland0.93350427
77MP0009780_abnormal_chondrocyte_physiolo0.93297940
78MP0004133_heterotaxia0.92251132
79MP0003631_nervous_system_phenotype0.91712134
80MP0002160_abnormal_reproductive_system0.90353598
81MP0005535_abnormal_body_temperature0.89950596
82MP0002234_abnormal_pharynx_morphology0.88288388
83MP0000026_abnormal_inner_ear0.87807517
84MP0003646_muscle_fatigue0.86210097
85MP0008872_abnormal_physiological_respon0.85085674
86MP0000631_abnormal_neuroendocrine_gland0.84892128
87MP0000013_abnormal_adipose_tissue0.84573935
88MP0000749_muscle_degeneration0.84177475
89MP0005084_abnormal_gallbladder_morpholo0.83755060
90MP0002152_abnormal_brain_morphology0.83114181
91MP0000427_abnormal_hair_cycle0.82390017
92MP0002069_abnormal_eating/drinking_beha0.82025434
93MP0001664_abnormal_digestion0.80361054
94MP0008874_decreased_physiological_sensi0.77866155
95MP0003186_abnormal_redox_activity0.77122744
96MP0004043_abnormal_pH_regulation0.76505115
97MP0005332_abnormal_amino_acid0.75869924
98MP0003634_abnormal_glial_cell0.75768033
99MP0004085_abnormal_heartbeat0.75197070
100MP0002102_abnormal_ear_morphology0.75041017
101MP0006035_abnormal_mitochondrial_morpho0.74744485
102MP0006072_abnormal_retinal_apoptosis0.74306172
103MP0002163_abnormal_gland_morphology0.73037043
104MP0006292_abnormal_olfactory_placode0.72862362
105MP0003632_abnormal_nervous_system0.71014647
106MP0004215_abnormal_myocardial_fiber0.70735953
107MP0004147_increased_porphyrin_level0.69899526
108MP0008875_abnormal_xenobiotic_pharmacok0.69503068
109MP0003690_abnormal_glial_cell0.68831277
110MP0003698_abnormal_male_reproductive0.68723041
111MP0002928_abnormal_bile_duct0.66995640
112MP0004484_altered_response_of0.66806511
113MP0003137_abnormal_impulse_conducting0.64746257
114MP0005499_abnormal_olfactory_system0.64621798
115MP0005394_taste/olfaction_phenotype0.64621798
116MP0004858_abnormal_nervous_system0.64603331
117MP0006036_abnormal_mitochondrial_physio0.60225531
118MP0002751_abnormal_autonomic_nervous0.59431571
119MP0005410_abnormal_fertilization0.58391329
120MP0001177_atelectasis0.57170049

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.37204052
2Atonic seizures (HP:0010819)5.28281613
3Myokymia (HP:0002411)4.92765627
4Febrile seizures (HP:0002373)4.50133495
5Epileptic encephalopathy (HP:0200134)4.41847110
6Focal seizures (HP:0007359)4.39426560
7Acute necrotizing encephalopathy (HP:0006965)4.33808551
8Abnormal mitochondria in muscle tissue (HP:0008316)3.96277549
9Progressive macrocephaly (HP:0004481)3.78468365
10Absence seizures (HP:0002121)3.78269685
11Mitochondrial inheritance (HP:0001427)3.66883994
12Hyperventilation (HP:0002883)3.62974307
13Dialeptic seizures (HP:0011146)3.57830532
14Acute encephalopathy (HP:0006846)3.47535199
15Generalized tonic-clonic seizures (HP:0002069)3.38889677
16Visual hallucinations (HP:0002367)3.34826718
17Progressive cerebellar ataxia (HP:0002073)3.29257127
18Increased CSF lactate (HP:0002490)3.13551378
19Hepatocellular necrosis (HP:0001404)3.07525754
20Broad-based gait (HP:0002136)3.05396613
21Pheochromocytoma (HP:0002666)3.00293023
22Abnormal hair whorl (HP:0010721)2.96480578
23Increased circulating renin level (HP:0000848)2.88246552
24Neuroendocrine neoplasm (HP:0100634)2.84436614
25Gaze-evoked nystagmus (HP:0000640)2.78602107
26Optic disc pallor (HP:0000543)2.74557877
27Hypothermia (HP:0002045)2.74348178
28Gait imbalance (HP:0002141)2.73128186
29Medial flaring of the eyebrow (HP:0010747)2.71580827
30Limb dystonia (HP:0002451)2.69187141
31Pancreatic fibrosis (HP:0100732)2.64987046
32Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.63264077
33Degeneration of the lateral corticospinal tracts (HP:0002314)2.63264077
34Congenital primary aphakia (HP:0007707)2.53611722
35Dysmetria (HP:0001310)2.50530777
36Methylmalonic acidemia (HP:0002912)2.49848052
37Sensory axonal neuropathy (HP:0003390)2.49632994
38Pancreatic cysts (HP:0001737)2.47142186
39Increased serum pyruvate (HP:0003542)2.46501886
40Abnormality of glycolysis (HP:0004366)2.46501886
41Abnormal eating behavior (HP:0100738)2.43926225
42Polyphagia (HP:0002591)2.43502447
43Increased hepatocellular lipid droplets (HP:0006565)2.42713048
44Abnormality of the labia minora (HP:0012880)2.42405573
45Fetal akinesia sequence (HP:0001989)2.41888333
46Type II lissencephaly (HP:0007260)2.41712980
47Nephrogenic diabetes insipidus (HP:0009806)2.40872164
48Renal Fanconi syndrome (HP:0001994)2.40677759
49True hermaphroditism (HP:0010459)2.40016872
50Progressive inability to walk (HP:0002505)2.38691669
51Hypoglycemic coma (HP:0001325)2.37563937
52Anxiety (HP:0000739)2.37441956
53Hemiparesis (HP:0001269)2.35848188
54Poor suck (HP:0002033)2.35488217
55Amblyopia (HP:0000646)2.34888667
56Leukodystrophy (HP:0002415)2.34886139
57Abnormality of midbrain morphology (HP:0002418)2.30768421
58Molar tooth sign on MRI (HP:0002419)2.30768421
59Abnormality of the corticospinal tract (HP:0002492)2.30075102
60Hepatic necrosis (HP:0002605)2.27276607
61Muscular hypotonia of the trunk (HP:0008936)2.25380532
62Cerebral edema (HP:0002181)2.25091809
63Inability to walk (HP:0002540)2.22051597
64Delusions (HP:0000746)2.21313703
65Neurofibrillary tangles (HP:0002185)2.20538705
66Supranuclear gaze palsy (HP:0000605)2.19224552
67Dynein arm defect of respiratory motile cilia (HP:0012255)2.17631915
68Absent/shortened dynein arms (HP:0200106)2.17631915
69Genital tract atresia (HP:0001827)2.16944935
70Intestinal atresia (HP:0011100)2.16581081
71Oligodactyly (hands) (HP:0001180)2.16281906
72Esotropia (HP:0000565)2.16023182
73Cerebral hypomyelination (HP:0006808)2.15722663
74Vaginal atresia (HP:0000148)2.14516864
75Abnormal ciliary motility (HP:0012262)2.14242735
76Dysdiadochokinesis (HP:0002075)2.13290966
77Scanning speech (HP:0002168)2.11687073
78Epileptiform EEG discharges (HP:0011182)2.11254843
79Lactic acidosis (HP:0003128)2.09566873
80Nephronophthisis (HP:0000090)2.09151789
81Truncal ataxia (HP:0002078)2.07796219
82Respiratory failure (HP:0002878)2.04745712
83Retinal dysplasia (HP:0007973)2.04240363
84Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.03850585
85Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.02811997
86Decreased activity of mitochondrial respiratory chain (HP:0008972)2.02389465
87Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.02389465
88X-linked dominant inheritance (HP:0001423)2.01021063
89Generalized myoclonic seizures (HP:0002123)2.00541379
90Decreased circulating renin level (HP:0003351)2.00192741
91Lipid accumulation in hepatocytes (HP:0006561)1.99598712
92Lissencephaly (HP:0001339)1.98075811
93Action tremor (HP:0002345)1.97881905
94Absent speech (HP:0001344)1.97246272
95Spastic gait (HP:0002064)1.96841245
96Drooling (HP:0002307)1.96830085
97Excessive salivation (HP:0003781)1.96830085
98Hyperinsulinemic hypoglycemia (HP:0000825)1.95218184
99Blue irides (HP:0000635)1.94412265
100Impaired vibration sensation in the lower limbs (HP:0002166)1.91151672
101EEG with generalized epileptiform discharges (HP:0011198)1.90987652
102Failure to thrive in infancy (HP:0001531)1.90822726
1033-Methylglutaconic aciduria (HP:0003535)1.89790829
104Poor coordination (HP:0002370)1.88802006
105Exercise intolerance (HP:0003546)1.88710142
106Specific learning disability (HP:0001328)1.87646147
107Increased intramyocellular lipid droplets (HP:0012240)1.87079876
108Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.87079498
109Cerebral inclusion bodies (HP:0100314)1.85618030
110Poor speech (HP:0002465)1.82987381
111Abnormal respiratory motile cilium physiology (HP:0012261)1.82069166
112Status epilepticus (HP:0002133)1.81170755
113Akinesia (HP:0002304)1.81111451
114Ankle clonus (HP:0011448)1.81050428
115Methylmalonic aciduria (HP:0012120)1.80297126
116Delayed gross motor development (HP:0002194)1.80189860
117Abnormal respiratory epithelium morphology (HP:0012253)1.79272571
118Abnormal respiratory motile cilium morphology (HP:0005938)1.79272571
119Pachygyria (HP:0001302)1.78958058
120Intention tremor (HP:0002080)1.77590914
121Abnormality of alanine metabolism (HP:0010916)1.76461577
122Hyperalaninemia (HP:0003348)1.76461577
123Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.76461577
124Optic nerve hypoplasia (HP:0000609)1.76027275
125Bundle branch block (HP:0011710)1.75967727
126CNS hypomyelination (HP:0003429)1.75487563
127Poor eye contact (HP:0000817)1.75386514
128Congenital malformation of the right heart (HP:0011723)1.74976143
129Double outlet right ventricle (HP:0001719)1.74976143
130Hypsarrhythmia (HP:0002521)1.74618279
131Urinary bladder sphincter dysfunction (HP:0002839)1.74443699
132Ketoacidosis (HP:0001993)1.71970048
133Renal cortical cysts (HP:0000803)1.71582528
134Hypoglycemic seizures (HP:0002173)1.69818313
135Exercise-induced muscle cramps (HP:0003710)1.69552911
136Aplasia/Hypoplasia of the tibia (HP:0005772)1.69112771
137Abnormality of the renal cortex (HP:0011035)1.68630720

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.70320822
2MAP3K123.69390824
3NTRK33.36344798
4FRK3.20599497
5MAP2K73.15414205
6EPHA42.92590475
7MAP3K42.82591738
8TNIK2.29804478
9TRIM282.27223161
10OXSR12.26812894
11MAP4K22.26784279
12CDK192.25478112
13MINK12.06121290
14MAP2K42.03878501
15PNCK2.02886309
16ERBB32.02141409
17PLK21.89505672
18ARAF1.79574494
19STK391.76564781
20MAP3K91.74655194
21PRPF4B1.73052318
22GRK51.68109690
23NME11.65498539
24MARK11.64741034
25MAPK131.54808797
26BMPR21.53632692
27OBSCN1.39711419
28GRK71.35219174
29RIPK41.34900908
30DAPK21.29749327
31BCR1.29149357
32GRK11.25953489
33CAMK2A1.23811859
34BCKDK1.22902705
35NTRK21.22410629
36CAMK2B1.22219286
37STK161.21706946
38MUSK1.20031314
39AKT31.19192213
40CDK51.13836362
41PRKCG1.12558106
42SGK4941.08519126
43SGK2231.08519126
44DAPK11.08063777
45UHMK11.06603354
46PAK61.05943789
47FES1.04975003
48BRAF1.00742967
49CAMKK20.99510433
50NTRK10.98735900
51TNK20.96875268
52WNK40.95517069
53ADRBK20.95431696
54NEK60.93095118
55STK38L0.91602282
56SIK30.91101668
57PRKCE0.88089539
58DYRK20.88048002
59CCNB10.86893853
60CSNK1G20.86315834
61CAMK2D0.85073563
62MAPKAPK50.82833602
63CAMK2G0.80659479
64PLK30.78952937
65EPHA30.78594323
66FGR0.77837707
67SGK20.76522327
68CSNK1G30.76338970
69PINK10.75595534
70MAP2K60.75100390
71DYRK1A0.74526339
72TIE10.73368758
73PKN10.72891499
74BMPR1B0.70470303
75PHKG10.70017936
76PHKG20.70017936
77KSR10.69396585
78CDK180.69368344
79PDK20.67816244
80ACVR1B0.67645764
81CDK140.66730891
82TSSK60.65652538
83WNK10.64356629
84KSR20.63773436
85MAP3K130.62363335
86CDK150.62335093
87ADRBK10.61085797
88CDK30.60577115
89PTK2B0.57500445
90MYLK0.56757626
91ROCK20.56628984
92MAP3K60.55728919
93IRAK20.55466881
94FGFR20.55159872
95INSRR0.54193917
96LMTK20.53976673
97CDK11A0.53126867
98WNK30.51439340
99CSNK1G10.51038012
100CAMK10.50426017
101PRKACA0.49809252
102PRKCI0.49639280
103STK110.48053624
104LIMK10.47694675
105PRKCZ0.47452655
106SGK10.46373689
107MAP3K20.45665387
108MST40.45478447
109BRSK10.42376595
110PRKACB0.42342388
111EIF2AK30.42208780
112CSNK1D0.41136496
113CAMK40.40985418
114CSNK1A1L0.40953495
115PAK30.40045578
116NEK10.40030017
117PLK10.39491019
118CSNK1E0.39213036
119ERBB40.39051627
120CSNK1A10.38964293
121ZAK0.38838893
122PRKAA10.38296816
123CAMKK10.37866619
124RAF10.36715564
125PRKG10.36549866
126FER0.36316066
127MKNK20.36228602
128YES10.36083048
129PDK30.33149726

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.05910736
2Oxidative phosphorylation_Homo sapiens_hsa001903.72454665
3Synaptic vesicle cycle_Homo sapiens_hsa047213.47397419
4Collecting duct acid secretion_Homo sapiens_hsa049663.07818848
5Parkinsons disease_Homo sapiens_hsa050122.81580223
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.69979529
7GABAergic synapse_Homo sapiens_hsa047272.51120337
8Alzheimers disease_Homo sapiens_hsa050102.49223408
9Morphine addiction_Homo sapiens_hsa050322.30192092
10Glutamatergic synapse_Homo sapiens_hsa047242.20698272
11Amphetamine addiction_Homo sapiens_hsa050312.16901426
12Circadian entrainment_Homo sapiens_hsa047132.14904438
13Taste transduction_Homo sapiens_hsa047422.14490158
14Olfactory transduction_Homo sapiens_hsa047402.11086759
15Long-term potentiation_Homo sapiens_hsa047202.02822851
16Serotonergic synapse_Homo sapiens_hsa047262.01454224
17Huntingtons disease_Homo sapiens_hsa050161.92428058
18Dopaminergic synapse_Homo sapiens_hsa047281.85357301
19Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.85328456
20Vibrio cholerae infection_Homo sapiens_hsa051101.79705117
21Cardiac muscle contraction_Homo sapiens_hsa042601.78504729
22Propanoate metabolism_Homo sapiens_hsa006401.78346332
23Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.74931779
24Salivary secretion_Homo sapiens_hsa049701.74046303
25Maturity onset diabetes of the young_Homo sapiens_hsa049501.70924205
26Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.64891567
27Insulin secretion_Homo sapiens_hsa049111.60019775
28Long-term depression_Homo sapiens_hsa047301.51325908
29Phototransduction_Homo sapiens_hsa047441.48806294
30Cholinergic synapse_Homo sapiens_hsa047251.42359063
31Renin secretion_Homo sapiens_hsa049241.42287341
32Cocaine addiction_Homo sapiens_hsa050301.42130924
33Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.41082033
34Calcium signaling pathway_Homo sapiens_hsa040201.39814268
35Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.35755195
36Fatty acid elongation_Homo sapiens_hsa000621.29681071
37Gastric acid secretion_Homo sapiens_hsa049711.28693527
38Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.24495775
39Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.23892770
40Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.23291198
41Folate biosynthesis_Homo sapiens_hsa007901.18469789
42Oxytocin signaling pathway_Homo sapiens_hsa049211.12107881
43Peroxisome_Homo sapiens_hsa041461.10417932
44Aldosterone synthesis and secretion_Homo sapiens_hsa049251.10053683
45Basal transcription factors_Homo sapiens_hsa030221.05047085
46Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.04573998
47Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.01152801
48beta-Alanine metabolism_Homo sapiens_hsa004101.00534478
49Primary bile acid biosynthesis_Homo sapiens_hsa001201.00470529
50Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.00348454
51Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.99660971
52Rheumatoid arthritis_Homo sapiens_hsa053230.99541069
53Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.95270939
54Nitrogen metabolism_Homo sapiens_hsa009100.94514426
55Vitamin B6 metabolism_Homo sapiens_hsa007500.93913647
562-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.89617330
57GnRH signaling pathway_Homo sapiens_hsa049120.88940204
58SNARE interactions in vesicular transport_Homo sapiens_hsa041300.86704046
59Gap junction_Homo sapiens_hsa045400.85452330
60Regulation of autophagy_Homo sapiens_hsa041400.83198284
61cAMP signaling pathway_Homo sapiens_hsa040240.82360464
62Axon guidance_Homo sapiens_hsa043600.81690845
63Butanoate metabolism_Homo sapiens_hsa006500.81476757
64Arginine and proline metabolism_Homo sapiens_hsa003300.79883253
65Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.79418751
66RNA polymerase_Homo sapiens_hsa030200.78886134
67Ether lipid metabolism_Homo sapiens_hsa005650.77832693
68Protein export_Homo sapiens_hsa030600.76188839
69Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.75591554
70Vascular smooth muscle contraction_Homo sapiens_hsa042700.75567687
71RNA degradation_Homo sapiens_hsa030180.75324465
72Sulfur metabolism_Homo sapiens_hsa009200.74761422
73Phosphatidylinositol signaling system_Homo sapiens_hsa040700.70765132
74Arginine biosynthesis_Homo sapiens_hsa002200.70657115
75Fatty acid metabolism_Homo sapiens_hsa012120.70281689
76Tryptophan metabolism_Homo sapiens_hsa003800.69316278
77Fanconi anemia pathway_Homo sapiens_hsa034600.68826202
78Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.68718536
79Pyruvate metabolism_Homo sapiens_hsa006200.64006986
80Cysteine and methionine metabolism_Homo sapiens_hsa002700.63698274
81Selenocompound metabolism_Homo sapiens_hsa004500.63602207
82Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.63482305
83Melanogenesis_Homo sapiens_hsa049160.61040412
84Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.57419527
85Pancreatic secretion_Homo sapiens_hsa049720.56639136
86Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.55757325
87Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.55310271
88cGMP-PKG signaling pathway_Homo sapiens_hsa040220.54326572
89Purine metabolism_Homo sapiens_hsa002300.53104510
90Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.52243914
91ErbB signaling pathway_Homo sapiens_hsa040120.51901307
92Circadian rhythm_Homo sapiens_hsa047100.50463002
93Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.50261471
94Phagosome_Homo sapiens_hsa041450.49234716
95Sphingolipid metabolism_Homo sapiens_hsa006000.48513253
96Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.46797851
97Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.45652987
98Ovarian steroidogenesis_Homo sapiens_hsa049130.45178803
99Mineral absorption_Homo sapiens_hsa049780.44845218
100Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.44263919
101Estrogen signaling pathway_Homo sapiens_hsa049150.43972934
102Linoleic acid metabolism_Homo sapiens_hsa005910.42723125
103Oocyte meiosis_Homo sapiens_hsa041140.42347256
104Carbon metabolism_Homo sapiens_hsa012000.41939785
105Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.41705722
106Ras signaling pathway_Homo sapiens_hsa040140.41493537
107Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.40693669
108Glycerophospholipid metabolism_Homo sapiens_hsa005640.39513419
109Type I diabetes mellitus_Homo sapiens_hsa049400.37737393
110Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.37669906
111Fatty acid degradation_Homo sapiens_hsa000710.37486828
112Steroid biosynthesis_Homo sapiens_hsa001000.35629567
113Metabolic pathways_Homo sapiens_hsa011000.33625804
114Thyroid hormone synthesis_Homo sapiens_hsa049180.32875850
115Dorso-ventral axis formation_Homo sapiens_hsa043200.32457581
116Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.32249212
117MAPK signaling pathway_Homo sapiens_hsa040100.32077613
118Type II diabetes mellitus_Homo sapiens_hsa049300.30624762
119Inositol phosphate metabolism_Homo sapiens_hsa005620.29951520
120Tyrosine metabolism_Homo sapiens_hsa003500.29903697
121Alcoholism_Homo sapiens_hsa050340.29052795
122Choline metabolism in cancer_Homo sapiens_hsa052310.28442344
123Dilated cardiomyopathy_Homo sapiens_hsa054140.28323234
124Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.28061084
125Phenylalanine metabolism_Homo sapiens_hsa003600.25695442
126African trypanosomiasis_Homo sapiens_hsa051430.25369230
127Phospholipase D signaling pathway_Homo sapiens_hsa040720.24973927
128Glucagon signaling pathway_Homo sapiens_hsa049220.24451873
129Proteasome_Homo sapiens_hsa030500.22830830

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