NEIL3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic chromosome condensation (GO:0007076)6.05494887
2attachment of spindle microtubules to kinetochore (GO:0008608)6.02266258
3protein localization to kinetochore (GO:0034501)5.97438805
4kinetochore organization (GO:0051383)5.89431415
5meiotic chromosome segregation (GO:0045132)5.70111363
6mitotic sister chromatid segregation (GO:0000070)5.55605002
7CENP-A containing nucleosome assembly (GO:0034080)5.55597462
8protein localization to chromosome, centromeric region (GO:0071459)5.46617342
9sister chromatid segregation (GO:0000819)5.35690456
10chromatin remodeling at centromere (GO:0031055)5.26415505
11nuclear pore complex assembly (GO:0051292)5.22567672
12mitotic metaphase plate congression (GO:0007080)5.19144362
13kinetochore assembly (GO:0051382)5.16371297
14metaphase plate congression (GO:0051310)4.86853251
15DNA replication-independent nucleosome organization (GO:0034724)4.78745288
16DNA replication-independent nucleosome assembly (GO:0006336)4.78745288
17nuclear pore organization (GO:0006999)4.76887288
18establishment of chromosome localization (GO:0051303)4.76004972
19mitotic recombination (GO:0006312)4.75850772
20telomere maintenance via semi-conservative replication (GO:0032201)4.74148479
21telomere maintenance via recombination (GO:0000722)4.62235496
22microtubule depolymerization (GO:0007019)4.40051432
23regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.33965384
24histone exchange (GO:0043486)4.30913295
25DNA strand elongation involved in DNA replication (GO:0006271)4.28291831
26DNA replication checkpoint (GO:0000076)4.25331669
27chromosome segregation (GO:0007059)4.20243606
28protein localization to chromosome (GO:0034502)4.14664150
29DNA strand elongation (GO:0022616)4.14275822
30regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.10274052
31DNA synthesis involved in DNA repair (GO:0000731)4.02580074
32regulation of spindle organization (GO:0090224)4.00638850
33spindle checkpoint (GO:0031577)3.99655902
34pore complex assembly (GO:0046931)3.97430854
35DNA replication initiation (GO:0006270)3.93344151
36DNA topological change (GO:0006265)3.93327367
37mitotic sister chromatid cohesion (GO:0007064)3.92208663
38nucleotide-excision repair, DNA gap filling (GO:0006297)3.90590255
39regulation of DNA endoreduplication (GO:0032875)3.87976741
40DNA unwinding involved in DNA replication (GO:0006268)3.87809258
41telomere maintenance via telomere lengthening (GO:0010833)3.84350577
42positive regulation of mitotic sister chromatid separation (GO:1901970)3.83896209
43positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.83896209
44positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.83896209
45establishment of integrated proviral latency (GO:0075713)3.81172692
46histone-serine phosphorylation (GO:0035404)3.77084834
47DNA ligation (GO:0006266)3.75094468
48V(D)J recombination (GO:0033151)3.73567228
49regulation of chromosome segregation (GO:0051983)3.69910112
50negative regulation of DNA-dependent DNA replication (GO:2000104)3.68762084
51spindle assembly checkpoint (GO:0071173)3.68562651
52protein K6-linked ubiquitination (GO:0085020)3.64282426
53regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.64133474
54maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.61990726
55regulation of mitotic metaphase/anaphase transition (GO:0030071)3.60005053
56negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.59996163
57double-strand break repair via nonhomologous end joining (GO:0006303)3.54543755
58non-recombinational repair (GO:0000726)3.54543755
59negative regulation of mitotic sister chromatid separation (GO:2000816)3.54491333
60negative regulation of mitotic sister chromatid segregation (GO:0033048)3.54491333
61negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.54491333
62negative regulation of sister chromatid segregation (GO:0033046)3.54491333
63regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.54438500
64chromosome condensation (GO:0030261)3.54088639
65negative regulation of chromosome segregation (GO:0051985)3.53665038
66DNA strand renaturation (GO:0000733)3.52927701
67chromatin assembly or disassembly (GO:0006333)3.52910003
68regulation of sister chromatid segregation (GO:0033045)3.51442240
69regulation of mitotic sister chromatid separation (GO:0010965)3.51442240
70regulation of mitotic sister chromatid segregation (GO:0033047)3.51442240
71mismatch repair (GO:0006298)3.50096763
72positive regulation of chromosome segregation (GO:0051984)3.46913129
73mitotic spindle assembly checkpoint (GO:0007094)3.45579458
74positive regulation of DNA-dependent DNA replication (GO:2000105)3.43620397
75negative regulation of mitosis (GO:0045839)3.42751216
76regulation of centrosome duplication (GO:0010824)3.40976910
77regulation of double-strand break repair via homologous recombination (GO:0010569)3.36608435
78mitotic spindle checkpoint (GO:0071174)3.35530462
79DNA packaging (GO:0006323)3.34679273
80telomere maintenance (GO:0000723)3.32904844
81DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla3.32216821
82spindle assembly involved in mitosis (GO:0090307)3.31204543
83regulation of mitotic spindle organization (GO:0060236)3.29059918
84telomere organization (GO:0032200)3.29035214
85regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.28862652
86regulation of mitotic spindle checkpoint (GO:1903504)3.28862652
87microtubule polymerization or depolymerization (GO:0031109)3.28772095
88deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.28538754
89mitotic nuclear envelope disassembly (GO:0007077)3.26740522
90mitotic G2 DNA damage checkpoint (GO:0007095)3.26508100
91regulation of sister chromatid cohesion (GO:0007063)3.26096509
92ATP-dependent chromatin remodeling (GO:0043044)3.23861179
93replication fork processing (GO:0031297)3.22844439
94regulation of nuclear cell cycle DNA replication (GO:0033262)3.22654603
95DNA damage response, signal transduction resulting in transcription (GO:0042772)3.22377079
96mitotic spindle organization (GO:0007052)3.21172044
97DNA replication-dependent nucleosome assembly (GO:0006335)3.21072181
98DNA replication-dependent nucleosome organization (GO:0034723)3.21072181
99synapsis (GO:0007129)3.16832949
100negative regulation of cell division (GO:0051782)3.10943508
101translesion synthesis (GO:0019985)3.10563650
102microtubule anchoring (GO:0034453)3.10510604
103sister chromatid cohesion (GO:0007062)3.09380660
104deoxyribonucleotide biosynthetic process (GO:0009263)3.09187847
105mitotic G2/M transition checkpoint (GO:0044818)3.08220970
106regulation of centriole replication (GO:0046599)3.07431503
107negative regulation of cell cycle G2/M phase transition (GO:1902750)3.07137639
108centriole replication (GO:0007099)3.05767183
109mitotic cell cycle (GO:0000278)3.05452472
110DNA double-strand break processing (GO:0000729)3.01937531
111regulation of exit from mitosis (GO:0007096)3.00596880
112regulation of centrosome cycle (GO:0046605)3.00238123
113negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)3.00213558
114resolution of meiotic recombination intermediates (GO:0000712)2.97476897
115DNA conformation change (GO:0071103)2.96875549
116nuclear envelope disassembly (GO:0051081)2.96402482
117membrane disassembly (GO:0030397)2.96402482
118chromosome organization (GO:0051276)2.96184582

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human8.12483993
2E2F4_17652178_ChIP-ChIP_JURKAT_Human5.44267206
3FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human5.07971218
4MYCN_21190229_ChIP-Seq_SHEP-21N_Human3.01773482
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.75871317
6E2F1_21310950_ChIP-Seq_MCF-7_Human2.66727442
7AR_21909140_ChIP-Seq_LNCAP_Human2.62624356
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.58060796
9E2F7_22180533_ChIP-Seq_HELA_Human11.7518638
10MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.97523484
11MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.94117569
12KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.90264576
13ELF1_17652178_ChIP-ChIP_JURKAT_Human1.87217245
14TP63_19390658_ChIP-ChIP_HaCaT_Human1.82913555
15CIITA_25753668_ChIP-Seq_RAJI_Human1.70131205
16HOXB4_20404135_ChIP-ChIP_EML_Mouse1.70007270
17MYC_18555785_ChIP-Seq_MESCs_Mouse1.69563279
18SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.69053655
19IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.68532111
20FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.63272088
21EST1_17652178_ChIP-ChIP_JURKAT_Human1.62092738
22PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.61603366
23FOXP3_21729870_ChIP-Seq_TREG_Human1.60866435
24VDR_23849224_ChIP-Seq_CD4+_Human1.57116588
25HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.50482315
26ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.50234860
27SCL_19346495_ChIP-Seq_HPC-7_Human1.49386834
28EGR1_19374776_ChIP-ChIP_THP-1_Human1.47959396
29ELK1_19687146_ChIP-ChIP_HELA_Human1.47269669
30SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.45436737
31NELFA_20434984_ChIP-Seq_ESCs_Mouse1.42908527
32MYC_19030024_ChIP-ChIP_MESCs_Mouse1.42859583
33YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.42595311
34POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.42367305
35MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.34931781
36DCP1A_22483619_ChIP-Seq_HELA_Human1.31344543
37E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.30049824
38GABP_17652178_ChIP-ChIP_JURKAT_Human1.29220047
39MYCN_18555785_ChIP-Seq_MESCs_Mouse1.27887136
40MYC_18358816_ChIP-ChIP_MESCs_Mouse1.26707352
41IRF8_21731497_ChIP-ChIP_J774_Mouse1.26230836
42JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.25484778
43E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.25354496
44ERG_20887958_ChIP-Seq_HPC-7_Mouse1.23874201
45HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.23234390
46ZFX_18555785_ChIP-Seq_MESCs_Mouse1.22928620
47SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.22164218
48FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.22012083
49SALL1_21062744_ChIP-ChIP_HESCs_Human1.21840970
50STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.20890242
51CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.20815670
52PADI4_21655091_ChIP-ChIP_MCF-7_Human1.17536259
53EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.16317063
54ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.13144580
55SPI1_23547873_ChIP-Seq_NB4_Human1.12344510
56CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.12129294
57* EWS_26573619_Chip-Seq_HEK293_Human1.11919618
58NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.11616505
59POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.11611583
60RBPJ_22232070_ChIP-Seq_NCS_Mouse1.10692677
61SRF_21415370_ChIP-Seq_HL-1_Mouse1.10624025
62TTF2_22483619_ChIP-Seq_HELA_Human1.09856051
63MYC_18940864_ChIP-ChIP_HL60_Human1.09507113
64GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.07183350
65FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.03912502
66CREB1_15753290_ChIP-ChIP_HEK293T_Human1.03591323
67ETS1_20019798_ChIP-Seq_JURKAT_Human1.01097896
68TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.00424009
69MYC_19079543_ChIP-ChIP_MESCs_Mouse0.98237895
70XRN2_22483619_ChIP-Seq_HELA_Human0.98109890
71GABP_19822575_ChIP-Seq_HepG2_Human0.97902000
72IRF8_22096565_ChIP-ChIP_GC-B_Human0.95880833
73PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.95283358
74IGF1R_20145208_ChIP-Seq_DFB_Human0.95210365
75SOX2_18555785_ChIP-Seq_MESCs_Mouse0.94932490
76* E2F1_18555785_ChIP-Seq_MESCs_Mouse0.94444666
77MYC_22102868_ChIP-Seq_BL_Human0.93634220
78MYB_21317192_ChIP-Seq_ERMYB_Mouse0.91662563
79THAP11_20581084_ChIP-Seq_MESCs_Mouse0.91127017
80TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.89768895
81KDM5A_27292631_Chip-Seq_BREAST_Human0.88895377
82* MYB_26560356_Chip-Seq_TH2_Human0.88066769
83NANOG_18555785_ChIP-Seq_MESCs_Mouse0.87667296
84FLI1_27457419_Chip-Seq_LIVER_Mouse0.86419999
85SOX2_16153702_ChIP-ChIP_HESCs_Human0.86130126
86PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.86005287
87SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.85394291
88HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.85291710
89PCGF2_27294783_Chip-Seq_ESCs_Mouse0.84583583
90VDR_21846776_ChIP-Seq_THP-1_Human0.84289036
91MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.82308378
92NOTCH1_21737748_ChIP-Seq_TLL_Human0.82260310
93CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.82115854
94NANOG_16153702_ChIP-ChIP_HESCs_Human0.81939560
95STAT4_19710469_ChIP-ChIP_TH1__Mouse0.81164851
96SOX17_20123909_ChIP-Seq_XEN_Mouse0.80376131
97IRF1_19129219_ChIP-ChIP_H3396_Human0.79807107
98CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.77369611
99MYB_26560356_Chip-Seq_TH1_Human0.77318820
100BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.76362537
101CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.74168581
102GATA2_22383799_ChIP-Seq_G1ME_Mouse0.73458420
103POU3F2_20337985_ChIP-ChIP_501MEL_Human0.72946396
104SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.72573633
105FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.72330311
106NFE2_27457419_Chip-Seq_LIVER_Mouse0.72279135
107RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.72127023
108CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.71760054
109IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.69481854
110FUS_26573619_Chip-Seq_HEK293_Human0.69443672
111VDR_22108803_ChIP-Seq_LS180_Human0.69000477
112CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.68658483
113CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.68209488
114KAP1_22055183_ChIP-Seq_ESCs_Mouse0.67535642
115DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.67113011
116LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.64268553
117POU5F1_16153702_ChIP-ChIP_HESCs_Human0.64227254
118ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.64190997
119FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.63928598
120* KLF4_18555785_ChIP-Seq_MESCs_Mouse0.63910730
121CHD1_26751641_Chip-Seq_LNCaP_Human0.63390305
122ZNF274_21170338_ChIP-Seq_K562_Hela0.62616618
123YY1_21170310_ChIP-Seq_MESCs_Mouse0.58566863
124FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.55874669
125TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.55666100
126TFEB_21752829_ChIP-Seq_HELA_Human0.54391761
127KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.53990547
128CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.53609030

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability5.12189417
2MP0003693_abnormal_embryo_hatching4.81329607
3MP0003111_abnormal_nucleus_morphology4.43598474
4MP0008057_abnormal_DNA_replication3.82148890
5MP0003077_abnormal_cell_cycle3.65542576
6MP0008058_abnormal_DNA_repair3.42363681
7MP0002396_abnormal_hematopoietic_system2.96450154
8MP0000569_abnormal_digit_pigmentation2.78315218
9MP0004957_abnormal_blastocyst_morpholog2.62681195
10MP0008877_abnormal_DNA_methylation2.53385698
11MP0008007_abnormal_cellular_replicative2.41919081
12MP0003787_abnormal_imprinting2.12067690
13MP0008932_abnormal_embryonic_tissue1.97424670
14MP0000490_abnormal_crypts_of1.95198645
15MP0000015_abnormal_ear_pigmentation1.94473545
16MP0005174_abnormal_tail_pigmentation1.88026805
17MP0004147_increased_porphyrin_level1.87752867
18MP0004808_abnormal_hematopoietic_stem1.84217552
19MP0002102_abnormal_ear_morphology1.80685694
20MP0003121_genomic_imprinting1.75588603
21MP0006292_abnormal_olfactory_placode1.74295410
22MP0003718_maternal_effect1.73334285
23MP0002095_abnormal_skin_pigmentation1.67323209
24MP0003763_abnormal_thymus_physiology1.66739333
25MP0001188_hyperpigmentation1.64090849
26MP0010307_abnormal_tumor_latency1.62622658
27MP0003786_premature_aging1.55767014
28MP0010352_gastrointestinal_tract_polyps1.51972487
29MP0002398_abnormal_bone_marrow1.50422433
30MP0001835_abnormal_antigen_presentation1.49493471
31MP0009697_abnormal_copulation1.48815085
32MP0000566_synostosis1.47764288
33MP0001119_abnormal_female_reproductive1.45533064
34MP0000350_abnormal_cell_proliferation1.44258689
35MP0001986_abnormal_taste_sensitivity1.41141091
36MP0000703_abnormal_thymus_morphology1.38245221
37MP0002877_abnormal_melanocyte_morpholog1.37012091
38MP0002019_abnormal_tumor_incidence1.34690913
39MP0004197_abnormal_fetal_growth/weight/1.30715598
40MP0001293_anophthalmia1.30681744
41MP0002210_abnormal_sex_determination1.29138541
42MP0005397_hematopoietic_system_phenotyp1.29111651
43MP0001545_abnormal_hematopoietic_system1.29111651
44MP0002084_abnormal_developmental_patter1.25995363
45MP0010030_abnormal_orbit_morphology1.23869689
46MP0000313_abnormal_cell_death1.23298920
47MP0002009_preneoplasia1.22579705
48MP0002722_abnormal_immune_system1.22256298
49MP0000689_abnormal_spleen_morphology1.22155357
50MP0001800_abnormal_humoral_immune1.19189297
51MP0001286_abnormal_eye_development1.18727122
52MP0000372_irregular_coat_pigmentation1.15548520
53MP0001929_abnormal_gametogenesis1.12691391
54MP0002420_abnormal_adaptive_immunity1.10920592
55MP0001819_abnormal_immune_cell1.09561037
56MP0002452_abnormal_antigen_presenting1.08650329
57MP0009278_abnormal_bone_marrow1.08372878
58MP0003656_abnormal_erythrocyte_physiolo1.08127379
59MP0003806_abnormal_nucleotide_metabolis1.08094808
60MP0005671_abnormal_response_to1.07897208
61MP0002132_abnormal_respiratory_system1.07778570
62MP0000716_abnormal_immune_system1.07650158
63MP0002429_abnormal_blood_cell1.07499454
64MP0003136_yellow_coat_color1.03827380
65MP0009785_altered_susceptibility_to1.00596469
66MP0001529_abnormal_vocalization0.99980463
67MP0005075_abnormal_melanosome_morpholog0.99316449
68MP0000653_abnormal_sex_gland0.98575677
69MP0006035_abnormal_mitochondrial_morpho0.96985127
70MP0003221_abnormal_cardiomyocyte_apopto0.96656216
71MP0001672_abnormal_embryogenesis/_devel0.96317161
72MP0005380_embryogenesis_phenotype0.96317161
73MP0003567_abnormal_fetal_cardiomyocyte0.93000128
74MP0000465_gastrointestinal_hemorrhage0.92882095
75MP0002160_abnormal_reproductive_system0.92653353
76MP0000358_abnormal_cell_content/0.92312002
77MP0003699_abnormal_female_reproductive0.91585866
78MP0009672_abnormal_birth_weight0.91441893
79MP0001873_stomach_inflammation0.91223710
80MP0001697_abnormal_embryo_size0.90787683
81MP0006072_abnormal_retinal_apoptosis0.90290421
82MP0003123_paternal_imprinting0.90283264
83MP0001186_pigmentation_phenotype0.90215921
84MP0002723_abnormal_immune_serum0.89569947
85MP0002697_abnormal_eye_size0.89004440
86MP0002419_abnormal_innate_immunity0.88662370
87MP0001730_embryonic_growth_arrest0.88590891
88MP0001145_abnormal_male_reproductive0.87469549
89MP0002405_respiratory_system_inflammati0.87419326
90MP0002075_abnormal_coat/hair_pigmentati0.85972407
91MP0000647_abnormal_sebaceous_gland0.85485521
92MP0001919_abnormal_reproductive_system0.85360577
93MP0005408_hypopigmentation0.84902662
94MP0009333_abnormal_splenocyte_physiolog0.84384539
95MP0002234_abnormal_pharynx_morphology0.84164633
96MP0002085_abnormal_embryonic_tissue0.83386973
97MP0001790_abnormal_immune_system0.82629429
98MP0005387_immune_system_phenotype0.82629429
99MP0000427_abnormal_hair_cycle0.81792429
100MP0002092_abnormal_eye_morphology0.79387738
101MP0005025_abnormal_response_to0.79290823
102MP0000383_abnormal_hair_follicle0.79026889
103MP0005076_abnormal_cell_differentiation0.78545661
104MP0002006_tumorigenesis0.78513466
105MP0002111_abnormal_tail_morphology0.78259892
106MP0003698_abnormal_male_reproductive0.77666206
107MP0000858_altered_metastatic_potential0.76443391
108MP0001346_abnormal_lacrimal_gland0.76065676
109MP0003890_abnormal_embryonic-extraembry0.75657658
110MP0005389_reproductive_system_phenotype0.75656764
111MP0005621_abnormal_cell_physiology0.74937507
112MP0003984_embryonic_growth_retardation0.74829552
113MP0003943_abnormal_hepatobiliary_system0.74606982
114MP0000685_abnormal_immune_system0.74531992
115MP0005464_abnormal_platelet_physiology0.74463167
116MP0002938_white_spotting0.73860437
117MP0002080_prenatal_lethality0.73276777
118MP0005000_abnormal_immune_tolerance0.72631792
119MP0000428_abnormal_craniofacial_morphol0.71615112
120MP0009703_decreased_birth_body0.70961487
121MP0002088_abnormal_embryonic_growth/wei0.70724467
122MP0008995_early_reproductive_senescence0.69629336
123MP0010155_abnormal_intestine_physiology0.69519165
124MP0003186_abnormal_redox_activity0.68286605
125MP0002161_abnormal_fertility/fecundity0.67867261
126MP0005384_cellular_phenotype0.66298821
127MP0002233_abnormal_nose_morphology0.65664908
128MP0005409_darkened_coat_color0.64857411
129MP0004381_abnormal_hair_follicle0.64476212
130MP0002086_abnormal_extraembryonic_tissu0.64235942
131MP0003861_abnormal_nervous_system0.64022323
132MP0002177_abnormal_outer_ear0.63622260
133MP0008961_abnormal_basal_metabolism0.63586725
134MP0003937_abnormal_limbs/digits/tail_de0.63100959
135MP0002928_abnormal_bile_duct0.62390086
136MP0003935_abnormal_craniofacial_develop0.62132314
137MP0006036_abnormal_mitochondrial_physio0.61682110
138MP0003315_abnormal_perineum_morphology0.61412722
139MP0005391_vision/eye_phenotype0.59962589
140MP0005395_other_phenotype0.58081173
141MP0005171_absent_coat_pigmentation0.55614441
142MP0005266_abnormal_metabolism0.55595772
143MP0002970_abnormal_white_adipose0.54211749
144MP0008789_abnormal_olfactory_epithelium0.54164222

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)7.10869634
2Chromsome breakage (HP:0040012)7.07524452
3Abnormality of chromosome stability (HP:0003220)4.54222307
4Aplasia/Hypoplasia of the uvula (HP:0010293)4.23159535
5Abnormality of the preputium (HP:0100587)4.13454805
6Meckel diverticulum (HP:0002245)3.98536398
7Abnormality of the ileum (HP:0001549)3.86564969
8Ectopic kidney (HP:0000086)3.59784666
9Duodenal stenosis (HP:0100867)3.48445440
10Small intestinal stenosis (HP:0012848)3.48445440
11Duplicated collecting system (HP:0000081)3.40899812
12Clubbing of toes (HP:0100760)3.40213605
13Abnormality of the renal collecting system (HP:0004742)3.34986455
14Cortical dysplasia (HP:0002539)3.30903557
15Birth length less than 3rd percentile (HP:0003561)3.26735014
16Myelodysplasia (HP:0002863)3.19855831
17Volvulus (HP:0002580)3.10644098
18Abnormality of the carotid arteries (HP:0005344)3.10353591
19Abnormality of DNA repair (HP:0003254)3.02160777
20Nephroblastoma (Wilms tumor) (HP:0002667)2.97471785
21Aplasia/Hypoplasia of the sacrum (HP:0008517)2.90058082
22Prostate neoplasm (HP:0100787)2.87785813
23Abnormality of the fingertips (HP:0001211)2.86676891
24Sloping forehead (HP:0000340)2.82103644
25Bone marrow hypocellularity (HP:0005528)2.81491883
26Abnormality of the duodenum (HP:0002246)2.77874466
27Embryonal renal neoplasm (HP:0011794)2.76929734
28Abnormality of the prostate (HP:0008775)2.74978247
29Patellar aplasia (HP:0006443)2.69795794
30Reticulocytopenia (HP:0001896)2.62500200
31Impulsivity (HP:0100710)2.60791269
32Recurrent abscess formation (HP:0002722)2.59317710
33Rhabdomyosarcoma (HP:0002859)2.58953340
34Abnormal lung lobation (HP:0002101)2.44889497
35Aplasia/Hypoplasia of the patella (HP:0006498)2.39786879
36Acute myeloid leukemia (HP:0004808)2.35073076
37Colon cancer (HP:0003003)2.33422760
38Short thumb (HP:0009778)2.32687192
39Abnormality of chromosome segregation (HP:0002916)2.31222272
40Increased nuchal translucency (HP:0010880)2.30841850
41Neoplasm of the colon (HP:0100273)2.26291980
42Recurrent bacterial skin infections (HP:0005406)2.25239543
43Oligodactyly (hands) (HP:0001180)2.18626887
44Panhypogammaglobulinemia (HP:0003139)2.11504801
45Choanal atresia (HP:0000453)2.09722227
46Deep philtrum (HP:0002002)2.08891142
47Abnormality of the heme biosynthetic pathway (HP:0010472)2.07860621
48Triphalangeal thumb (HP:0001199)2.04970445
49Hypoplasia of the capital femoral epiphysis (HP:0003090)2.02693203
50Aplastic anemia (HP:0001915)2.02564239
51Abnormality of the anterior horn cell (HP:0006802)2.01451747
52Degeneration of anterior horn cells (HP:0002398)2.01451747
53Ependymoma (HP:0002888)2.01111266
54IgM deficiency (HP:0002850)1.98729002
55Proximal placement of thumb (HP:0009623)1.97831544
56Cafe-au-lait spot (HP:0000957)1.97529632
57Short 4th metacarpal (HP:0010044)1.96318929
58Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.96318929
59High pitched voice (HP:0001620)1.95993226
60Absent thumb (HP:0009777)1.94837573
61Absent radius (HP:0003974)1.92392870
62Long clavicles (HP:0000890)1.91951900
63Tracheoesophageal fistula (HP:0002575)1.87664423
6411 pairs of ribs (HP:0000878)1.87565950
65Abnormality of B cell number (HP:0010975)1.87049047
66B lymphocytopenia (HP:0010976)1.87049047
67Medulloblastoma (HP:0002885)1.86835780
68Small hand (HP:0200055)1.85425615
69Leukopenia (HP:0001882)1.85136844
70Abnormal number of incisors (HP:0011064)1.85108477
71Type I transferrin isoform profile (HP:0003642)1.84863975
72Breast hypoplasia (HP:0003187)1.83782772
73Ovarian neoplasm (HP:0100615)1.83576912
74Lymphoma (HP:0002665)1.83020981
75Acute lymphatic leukemia (HP:0006721)1.82974573
76Aplasia/Hypoplasia of the earlobes (HP:0009906)1.82711379
77Selective tooth agenesis (HP:0001592)1.81745972
78Recurrent viral infections (HP:0004429)1.81170713
79Glioma (HP:0009733)1.80466021
80Oligohydramnios (HP:0001562)1.79359508
81Hypergonadotropic hypogonadism (HP:0000815)1.79112106
82True hermaphroditism (HP:0010459)1.78532205
83Deviation of the thumb (HP:0009603)1.78433325
84Embryonal neoplasm (HP:0002898)1.76815823
85Aplasia involving forearm bones (HP:0009822)1.76759065
86Absent forearm bone (HP:0003953)1.76759065
87Prominent nose (HP:0000448)1.76042091
88Facial hemangioma (HP:0000329)1.75721971
89Oligodactyly (HP:0012165)1.75656292
90Squamous cell carcinoma (HP:0002860)1.74164454
91Optic nerve coloboma (HP:0000588)1.72602952
92Abnormality of the labia minora (HP:0012880)1.72460067
93Poikiloderma (HP:0001029)1.71877242
94Combined immunodeficiency (HP:0005387)1.71805288
95Thyroiditis (HP:0100646)1.71143463
96Acute necrotizing encephalopathy (HP:0006965)1.71033286
97Arteriovenous malformation (HP:0100026)1.70698602
98Pulmonary fibrosis (HP:0002206)1.70652685
99Mesomelia (HP:0003027)1.69769543
100Astigmatism (HP:0000483)1.69315293
101Abnormal auditory evoked potentials (HP:0006958)1.67247297
102Meningitis (HP:0001287)1.66858445
103Abnormality of the astrocytes (HP:0100707)1.66435197
104Astrocytoma (HP:0009592)1.66435197
105Neoplasm of striated muscle (HP:0009728)1.66325383
106Premature graying of hair (HP:0002216)1.66309701
107Overlapping toe (HP:0001845)1.66207420
108Carpal bone hypoplasia (HP:0001498)1.66175008
109Pancreatic fibrosis (HP:0100732)1.65594703
110Duplication of thumb phalanx (HP:0009942)1.65403286
111Pancytopenia (HP:0001876)1.64191022
112Holoprosencephaly (HP:0001360)1.64057899
113Recurrent pneumonia (HP:0006532)1.63382548
114Horseshoe kidney (HP:0000085)1.63250696
115Mediastinal lymphadenopathy (HP:0100721)1.62150639
116Abnormality of the columella (HP:0009929)1.61597561
117Flared metaphyses (HP:0003015)1.61300834
118Short middle phalanx of the 5th finger (HP:0004220)1.61030003
119Severe combined immunodeficiency (HP:0004430)1.60851617
120Aplasia/Hypoplasia of the sternum (HP:0006714)1.60401134
121Flat capital femoral epiphysis (HP:0003370)1.59485233
122Acute encephalopathy (HP:0006846)1.58983603
123Supernumerary spleens (HP:0009799)1.58323508
124Agnosia (HP:0010524)1.57741052
125Abnormality of the fetal cardiovascular system (HP:0010948)1.56922612
126Abnormal umbilical cord blood vessels (HP:0011403)1.56922612
127Single umbilical artery (HP:0001195)1.56922612
128Lip pit (HP:0100267)1.56196591
129Optic neuritis (HP:0100653)1.56194960
130Retrobulbar optic neuritis (HP:0100654)1.56194960
131Reduced antithrombin III activity (HP:0001976)1.55827408
132Irregular epiphyses (HP:0010582)1.55821146
133Abnormal hair whorl (HP:0010721)1.55645837
134Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.55349417
135Agammaglobulinemia (HP:0004432)1.55116831
136Hypoplasia of the pons (HP:0012110)1.53358428
137Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.52990613
138Abnormality of alanine metabolism (HP:0010916)1.52990613
139Hyperalaninemia (HP:0003348)1.52990613
140Intestinal atresia (HP:0011100)1.52944736
141Microvesicular hepatic steatosis (HP:0001414)1.50993734
142Abnormal mitochondria in muscle tissue (HP:0008316)1.50525389

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.33855052
2NEK23.55044218
3CCNB13.37066155
4BUB13.20711949
5TTK3.19484439
6PLK43.13365115
7WEE12.65691292
8ZAK2.35150879
9PLK12.21637965
10STK42.14937162
11BRSK22.10792218
12VRK12.10737844
13AURKB2.05775136
14TAOK31.97721492
15ATR1.96025419
16SRPK11.95670183
17EIF2AK11.95137609
18BRSK11.94384664
19CHEK21.93733567
20ACVR1B1.90708267
21CLK11.63468873
22STK101.59748340
23TLK11.58765802
24TSSK61.58138007
25EIF2AK21.56869101
26VRK21.53855014
27TEC1.52413214
28MELK1.47113438
29TAF11.46769078
30MST41.43239174
31PNCK1.43159921
32CDK121.42870260
33PLK31.41588461
34TXK1.40447401
35CDK81.35944324
36IRAK41.33493849
37MKNK11.31480326
38CDK71.28062590
39PASK1.25331023
40CDK41.24352322
41NEK11.20261029
42MAP4K11.19768430
43BRAF1.18673837
44CDK91.12418686
45MKNK21.11069696
46MAP3K101.10107434
47AURKA1.07374277
48BRD41.04805508
49CHEK11.03734137
50ATM1.03059999
51SIK31.02468250
52MAP3K141.01326369
53TRIM281.00224910
54YES10.99709504
55RPS6KA40.98776582
56MAP3K80.97325896
57STK30.97099125
58BTK0.96692118
59STK160.94927406
60NUAK10.94375362
61MAP3K60.94037009
62PLK20.93354438
63BMPR20.91771693
64NEK90.91536776
65KIT0.89247910
66PIM10.88117785
67CDK30.87596569
68DYRK30.76971893
69SGK20.76842062
70CDK10.72437828
71TRPM70.67394338
72STK38L0.66115416
73JAK30.63989382
74CDK20.63873661
75ERBB30.61877053
76CHUK0.61638624
77CDK60.60859962
78BMPR1B0.60010782
79EIF2AK30.59521714
80SYK0.56980056
81RPS6KA50.56372111
82CSF1R0.55956700
83LYN0.55137754
84LATS10.55126935
85MAPK130.53990240
86MAPK110.48322753
87EEF2K0.47070814
88ERBB40.46510152
89STK240.43097216
90MAP3K40.42848046
91MUSK0.42133844
92BLK0.41778167
93CSNK2A20.39417403
94AKT10.38942201
95SCYL20.37107028
96ITK0.36630860
97PBK0.35065485
98TGFBR10.34387915
99CDK180.33849883
100MAPK140.33610070
101FLT30.33560740
102CSNK2A10.33517626
103SGK30.33505824
104TYK20.33035454
105CASK0.32815177
106TNIK0.32242369
107PRKCI0.32184979
108CDK150.32007856
109WNK40.31197441
110RPS6KB20.31186579
111MAP2K70.31094753
112MST1R0.30858567
113SMG10.30720720
114IKBKB0.30623775
115MOS0.28800889
116RAF10.28421026
117MARK30.28402246
118CDK140.27673937
119MAP3K130.27508682
120CDK11A0.27241754
121NLK0.26512476
122PDK20.26029329
123CSNK1G10.25326905
124PRKDC0.25024041
125PAK10.24503074
126CSNK1E0.19478403
127CSNK1G30.19017890
128CAMK1G0.18618132
129CSNK1A1L0.18178698
130BCR0.17746084
131WNK30.17717571
132KSR10.17503615
133PKN20.17222425
134MAPKAPK50.16405997
135NME20.15520298

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.94070700
2Mismatch repair_Homo sapiens_hsa034304.03103963
3Homologous recombination_Homo sapiens_hsa034403.94988865
4Fanconi anemia pathway_Homo sapiens_hsa034603.69384634
5Cell cycle_Homo sapiens_hsa041103.58775980
6* Base excision repair_Homo sapiens_hsa034103.39251013
7Non-homologous end-joining_Homo sapiens_hsa034502.96306238
8Nucleotide excision repair_Homo sapiens_hsa034202.69273755
9Spliceosome_Homo sapiens_hsa030402.00475433
10RNA degradation_Homo sapiens_hsa030182.00143813
11Basal transcription factors_Homo sapiens_hsa030221.91645391
12p53 signaling pathway_Homo sapiens_hsa041151.89149533
13Systemic lupus erythematosus_Homo sapiens_hsa053221.87481005
14One carbon pool by folate_Homo sapiens_hsa006701.82041607
15RNA transport_Homo sapiens_hsa030131.76116307
16Pyrimidine metabolism_Homo sapiens_hsa002401.75681210
17Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.69775103
18Primary immunodeficiency_Homo sapiens_hsa053401.46827266
19Herpes simplex infection_Homo sapiens_hsa051681.46083241
20mRNA surveillance pathway_Homo sapiens_hsa030151.40635602
21RNA polymerase_Homo sapiens_hsa030201.35889375
22Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.35446144
23Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.33432875
24NF-kappa B signaling pathway_Homo sapiens_hsa040641.28918130
25Cysteine and methionine metabolism_Homo sapiens_hsa002701.25874655
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.20274912
27Transcriptional misregulation in cancer_Homo sapiens_hsa052021.15984536
28Oocyte meiosis_Homo sapiens_hsa041141.12251820
29Hematopoietic cell lineage_Homo sapiens_hsa046401.11562861
30Purine metabolism_Homo sapiens_hsa002301.05657808
31Viral carcinogenesis_Homo sapiens_hsa052031.05148542
32Selenocompound metabolism_Homo sapiens_hsa004501.04848521
33Measles_Homo sapiens_hsa051621.03355655
34Intestinal immune network for IgA production_Homo sapiens_hsa046720.97372725
35MicroRNAs in cancer_Homo sapiens_hsa052060.96942643
36Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.96465201
37HTLV-I infection_Homo sapiens_hsa051660.96266654
38Pyruvate metabolism_Homo sapiens_hsa006200.95686876
39Pancreatic cancer_Homo sapiens_hsa052120.94222393
40Epstein-Barr virus infection_Homo sapiens_hsa051690.93902539
41Propanoate metabolism_Homo sapiens_hsa006400.92783404
42Hepatitis B_Homo sapiens_hsa051610.92101637
43Alcoholism_Homo sapiens_hsa050340.91605984
44Parkinsons disease_Homo sapiens_hsa050120.90932273
45Biosynthesis of amino acids_Homo sapiens_hsa012300.90025952
46Small cell lung cancer_Homo sapiens_hsa052220.88158804
47Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.87274407
48Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.86268016
49Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.84206434
50RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.80477340
51NOD-like receptor signaling pathway_Homo sapiens_hsa046210.80451755
52Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.79988204
53Huntingtons disease_Homo sapiens_hsa050160.78732159
54Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.78205276
55Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.77110371
56Apoptosis_Homo sapiens_hsa042100.75771336
57Steroid biosynthesis_Homo sapiens_hsa001000.75431612
58Influenza A_Homo sapiens_hsa051640.74807276
59Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.73151553
60Leishmaniasis_Homo sapiens_hsa051400.72574034
61Folate biosynthesis_Homo sapiens_hsa007900.71204483
62Oxidative phosphorylation_Homo sapiens_hsa001900.66899395
63Sulfur relay system_Homo sapiens_hsa041220.66344253
64Chronic myeloid leukemia_Homo sapiens_hsa052200.65821024
65Colorectal cancer_Homo sapiens_hsa052100.64989357
66Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.64574943
67B cell receptor signaling pathway_Homo sapiens_hsa046620.64258770
68Lysine degradation_Homo sapiens_hsa003100.63701295
69Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.63633521
70Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.63552517
71Proteasome_Homo sapiens_hsa030500.63407086
72Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.61741237
73Carbon metabolism_Homo sapiens_hsa012000.60633135
74Glutathione metabolism_Homo sapiens_hsa004800.60562629
75N-Glycan biosynthesis_Homo sapiens_hsa005100.60492937
762-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.59423010
77Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.58991344
78Fatty acid elongation_Homo sapiens_hsa000620.58722828
79Ribosome_Homo sapiens_hsa030100.55615433
80Toll-like receptor signaling pathway_Homo sapiens_hsa046200.54375822
81Ovarian steroidogenesis_Homo sapiens_hsa049130.54332397
82Antigen processing and presentation_Homo sapiens_hsa046120.54313257
83Allograft rejection_Homo sapiens_hsa053300.54256965
84FoxO signaling pathway_Homo sapiens_hsa040680.52410454
85Jak-STAT signaling pathway_Homo sapiens_hsa046300.52351728
86Shigellosis_Homo sapiens_hsa051310.50501945
87Protein export_Homo sapiens_hsa030600.50335985
88Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.49382251
89Autoimmune thyroid disease_Homo sapiens_hsa053200.49170429
90Notch signaling pathway_Homo sapiens_hsa043300.49099932
91Asthma_Homo sapiens_hsa053100.48461506
92Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.47481122
93Prostate cancer_Homo sapiens_hsa052150.46155735
94TNF signaling pathway_Homo sapiens_hsa046680.45099483
95Osteoclast differentiation_Homo sapiens_hsa043800.44362629
96Legionellosis_Homo sapiens_hsa051340.41780546
97Basal cell carcinoma_Homo sapiens_hsa052170.41769832
98Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.41570955
99Non-small cell lung cancer_Homo sapiens_hsa052230.40646923
100Hippo signaling pathway_Homo sapiens_hsa043900.39645552
101Graft-versus-host disease_Homo sapiens_hsa053320.39547590
102TGF-beta signaling pathway_Homo sapiens_hsa043500.39036173
103Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.38877628
104Circadian rhythm_Homo sapiens_hsa047100.38388189
105Viral myocarditis_Homo sapiens_hsa054160.38018705
106Pentose phosphate pathway_Homo sapiens_hsa000300.37434369
107Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.36455890
108Pathways in cancer_Homo sapiens_hsa052000.36316325
109Malaria_Homo sapiens_hsa051440.36255105
110Hedgehog signaling pathway_Homo sapiens_hsa043400.35783372
111Alzheimers disease_Homo sapiens_hsa050100.35095943
112Wnt signaling pathway_Homo sapiens_hsa043100.34453195
113T cell receptor signaling pathway_Homo sapiens_hsa046600.33067007
114Toxoplasmosis_Homo sapiens_hsa051450.32773057
115Metabolic pathways_Homo sapiens_hsa011000.32556732
116Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.32183434
117Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.31986190
118Arachidonic acid metabolism_Homo sapiens_hsa005900.31745064
119Acute myeloid leukemia_Homo sapiens_hsa052210.31205508
120Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.31033668
121Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.30108836
122Other glycan degradation_Homo sapiens_hsa005110.29740646
123Platelet activation_Homo sapiens_hsa046110.29150039
124Chemokine signaling pathway_Homo sapiens_hsa040620.29038169
125Vitamin B6 metabolism_Homo sapiens_hsa007500.28991934
126Tuberculosis_Homo sapiens_hsa051520.28960780
127SNARE interactions in vesicular transport_Homo sapiens_hsa041300.28224275
128Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.26992577
129Adherens junction_Homo sapiens_hsa045200.26120789
130Thyroid cancer_Homo sapiens_hsa052160.25581878
131Drug metabolism - other enzymes_Homo sapiens_hsa009830.23834926
132Hepatitis C_Homo sapiens_hsa051600.23536877
133Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.23311553
134Glycosaminoglycan degradation_Homo sapiens_hsa005310.22394881
135Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.20935206
136Melanoma_Homo sapiens_hsa052180.18962355
137Bladder cancer_Homo sapiens_hsa052190.16474581
138Nitrogen metabolism_Homo sapiens_hsa009100.15929287
139Fatty acid metabolism_Homo sapiens_hsa012120.14853946
140Olfactory transduction_Homo sapiens_hsa047400.08797710
141Central carbon metabolism in cancer_Homo sapiens_hsa052300.08749622
142Glioma_Homo sapiens_hsa052140.08434309
143Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.06307925
144Pentose and glucuronate interconversions_Homo sapiens_hsa000400.06219256
145Peroxisome_Homo sapiens_hsa041460.02779127

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