NECAP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene likely encodes a member of the adaptin-ear-binding coat-associated protein family. Studies of a similar protein in rat suggest a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants have been described. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.89842786
2negative regulation of cell killing (GO:0031342)4.89842786
3antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.39958601
4antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.39958601
5antigen processing and presentation of endogenous antigen (GO:0019883)4.33829244
6antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.26799595
7neutrophil activation involved in immune response (GO:0002283)4.21246520
8positive regulation by symbiont of host defense response (GO:0052509)4.05156510
9modulation by symbiont of host defense response (GO:0052031)4.05156510
10modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.05156510
11modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.05156510
12positive regulation by organism of defense response of other organism involved in symbiotic interact4.05156510
13modulation by symbiont of host immune response (GO:0052553)4.05156510
14negative regulation of interleukin-12 production (GO:0032695)3.98099696
15regulation of gamma-delta T cell activation (GO:0046643)3.83598958
16positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.70701630
17regulation of interferon-beta biosynthetic process (GO:0045357)3.69155773
18regulation of T cell tolerance induction (GO:0002664)3.65677707
19immunoglobulin mediated immune response (GO:0016064)3.58436570
20negative thymic T cell selection (GO:0045060)3.55246356
21negative T cell selection (GO:0043383)3.53140157
22positive regulation of interferon-alpha production (GO:0032727)3.53035530
23ribosomal small subunit assembly (GO:0000028)3.52274240
24detection of other organism (GO:0098543)3.51283788
25positive regulation of antigen processing and presentation (GO:0002579)3.43006027
26detection of bacterium (GO:0016045)3.42020529
27positive regulation of gamma-delta T cell activation (GO:0046645)3.37718411
28Arp2/3 complex-mediated actin nucleation (GO:0034314)3.37214727
29regulation of interferon-alpha production (GO:0032647)3.34033616
30positive thymic T cell selection (GO:0045059)3.33682919
31regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.29260699
32regulation of tolerance induction (GO:0002643)3.24150161
33NIK/NF-kappaB signaling (GO:0038061)3.21447431
34neutrophil activation (GO:0042119)3.15300733
35negative regulation of erythrocyte differentiation (GO:0045647)3.12109902
36regulation of natural killer cell mediated immunity (GO:0002715)3.11998986
37regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.11998986
38positive regulation of B cell differentiation (GO:0045579)3.10902155
39cellular extravasation (GO:0045123)3.09480973
40regulation of T cell mediated cytotoxicity (GO:0001914)3.09164340
41granulocyte activation (GO:0036230)3.07299574
42regulation of B cell receptor signaling pathway (GO:0050855)3.05653014
43DNA deamination (GO:0045006)3.04166915
44negative regulation of T cell mediated immunity (GO:0002710)3.03987317
45regulation of antigen processing and presentation (GO:0002577)3.03251461
46regulation of interleukin-2 biosynthetic process (GO:0045076)3.02836953
47response to interleukin-15 (GO:0070672)3.02436676
48positive regulation of T cell mediated cytotoxicity (GO:0001916)2.99789285
49positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.97045251
50thymic T cell selection (GO:0045061)2.95188637
51response to peptidoglycan (GO:0032494)2.94915010
52viral transcription (GO:0019083)2.94330685
53response to type I interferon (GO:0034340)2.91979194
54cellular response to type I interferon (GO:0071357)2.91625081
55type I interferon signaling pathway (GO:0060337)2.91625081
56response to muramyl dipeptide (GO:0032495)2.91610461
57detection of external biotic stimulus (GO:0098581)2.91340753
58myeloid dendritic cell activation (GO:0001773)2.90408326
59positive regulation of tolerance induction (GO:0002645)2.89845029
60T cell selection (GO:0045058)2.89798337
61negative regulation of lymphocyte mediated immunity (GO:0002707)2.89747110
62regulation of alpha-beta T cell proliferation (GO:0046640)2.89706003
63B cell mediated immunity (GO:0019724)2.89408478
64cellular response to zinc ion (GO:0071294)2.88184922
65respiratory burst (GO:0045730)2.87223787
66regulation of mast cell degranulation (GO:0043304)2.86987883
67regulation of dendritic cell antigen processing and presentation (GO:0002604)2.84673434
68cellular response to interleukin-15 (GO:0071350)2.83903125
69negative regulation of innate immune response (GO:0045824)2.83866261
70leukocyte aggregation (GO:0070486)2.83799926
71myeloid dendritic cell differentiation (GO:0043011)2.82552958
72macrophage activation involved in immune response (GO:0002281)2.81098274
73negative regulation of leukocyte mediated immunity (GO:0002704)2.80594167
74pinocytosis (GO:0006907)2.80337335
75antigen processing and presentation via MHC class Ib (GO:0002475)2.79846121
76dendritic cell differentiation (GO:0097028)2.79712277
77positive T cell selection (GO:0043368)2.76688684
78regulation of regulatory T cell differentiation (GO:0045589)2.75482974
79regulation of leukocyte mediated cytotoxicity (GO:0001910)2.74892913
80translational termination (GO:0006415)2.72857346
81interferon-gamma-mediated signaling pathway (GO:0060333)2.70118012
82T-helper 1 type immune response (GO:0042088)2.68887396
83regulation of B cell differentiation (GO:0045577)2.68157813
84cellular response to interferon-beta (GO:0035458)2.67911627
85regulation of protein heterodimerization activity (GO:0043497)2.66060568
86positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.65939352
87positive regulation of interferon-beta production (GO:0032728)2.65254258
88amino sugar catabolic process (GO:0046348)2.64137560
89positive regulation of type 2 immune response (GO:0002830)2.64008610
90detection of molecule of bacterial origin (GO:0032490)2.63511717
91positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.63321556
92natural killer cell mediated immunity (GO:0002228)2.63008358
93natural killer cell mediated cytotoxicity (GO:0042267)2.63008358
94positive regulation of immunoglobulin mediated immune response (GO:0002891)2.62870389
95positive regulation of B cell mediated immunity (GO:0002714)2.62870389
96response to interferon-beta (GO:0035456)2.62844692
97positive regulation of isotype switching (GO:0045830)2.62171883
98defense response to protozoan (GO:0042832)2.61988766
99germinal center formation (GO:0002467)2.61937379
100cellular response to interferon-gamma (GO:0071346)2.61922778
101heme biosynthetic process (GO:0006783)2.61719739
102positive regulation of interleukin-17 production (GO:0032740)2.61591775
103regulation of interleukin-12 biosynthetic process (GO:0045075)2.61495599
104negative regulation of cytokine production involved in immune response (GO:0002719)2.60695599
105T cell costimulation (GO:0031295)2.60242860
106regulation of mast cell activation involved in immune response (GO:0033006)2.59511068
107positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.58532634
108myeloid cell activation involved in immune response (GO:0002275)2.57560327
109positive regulation of NF-kappaB import into nucleus (GO:0042346)2.55855251
110negative regulation of phagocytosis (GO:0050765)2.54287935
111T cell migration (GO:0072678)2.54203346
112telomere maintenance via semi-conservative replication (GO:0032201)2.52830458
113lipopolysaccharide-mediated signaling pathway (GO:0031663)2.50994187
114deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.50168691
115response to protozoan (GO:0001562)2.50146956
116DNA strand elongation involved in DNA replication (GO:0006271)2.49816731
117B cell receptor signaling pathway (GO:0050853)2.49274091
118SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.47873975
119regulation of RIG-I signaling pathway (GO:0039535)2.46497442
120positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.45923909
121response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.45461036
122response to host immune response (GO:0052572)2.45461036
123actin nucleation (GO:0045010)2.44709207
124positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.42546396
125protein targeting to ER (GO:0045047)2.42136280
126leukocyte cell-cell adhesion (GO:0007159)2.41756829
127regulation of necroptotic process (GO:0060544)2.41648921
128positive regulation of natural killer cell differentiation (GO:0032825)2.40853098
129cotranslational protein targeting to membrane (GO:0006613)2.40444669
130positive regulation of macrophage differentiation (GO:0045651)2.39237720
131antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.35496397
132translational elongation (GO:0006414)2.35279256
133regulation of type I interferon-mediated signaling pathway (GO:0060338)2.34547329
134regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.33720654
135erythrocyte maturation (GO:0043249)2.33688525
136DNA strand elongation (GO:0022616)2.33207576
137ribosomal small subunit biogenesis (GO:0042274)2.32250507
138positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.31452687
139myeloid leukocyte activation (GO:0002274)2.30037336
140establishment of protein localization to endoplasmic reticulum (GO:0072599)2.29661216
141heme metabolic process (GO:0042168)2.29627744
142tolerance induction (GO:0002507)2.29208784
143response to interferon-alpha (GO:0035455)2.28824208
144positive regulation of interleukin-12 production (GO:0032735)2.27851723
145regulation of erythrocyte differentiation (GO:0045646)2.27661338
146dendritic cell chemotaxis (GO:0002407)2.27551945
147regulation of gamma-delta T cell differentiation (GO:0045586)2.27155714
148activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO2.27063913
149regulation of T-helper 1 cell differentiation (GO:0045625)2.27022231
150T cell apoptotic process (GO:0070231)2.26323000

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.49140710
2IRF8_22096565_ChIP-ChIP_GC-B_Human4.04082749
3* IRF8_21731497_ChIP-ChIP_J774_Mouse3.82520759
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.98697319
5IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.91634309
6* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.67325139
7BP1_19119308_ChIP-ChIP_Hs578T_Human2.66044064
8SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.60338452
9FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.50833988
10* IRF8_27001747_Chip-Seq_BMDM_Mouse2.45140516
11MYB_21317192_ChIP-Seq_ERMYB_Mouse2.35753601
12* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.32099510
13EGR1_19374776_ChIP-ChIP_THP-1_Human2.30119839
14NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.23620606
15VDR_21846776_ChIP-Seq_THP-1_Human2.22771670
16SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.22342975
17SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.16854451
18STAT4_19710469_ChIP-ChIP_TH1__Mouse2.10133851
19SPI1_23547873_ChIP-Seq_NB4_Human2.07113118
20MYC_22102868_ChIP-Seq_BL_Human2.00676876
21NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.95465563
22STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.94115561
23SCL_19346495_ChIP-Seq_HPC-7_Human1.93251877
24FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.86613871
25ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.83037647
26TP63_17297297_ChIP-ChIP_HaCaT_Human1.82699026
27MAF_26560356_Chip-Seq_TH1_Human1.80994772
28TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.79102860
29IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.78235491
30ELF1_17652178_ChIP-ChIP_JURKAT_Human1.76136074
31VDR_24763502_ChIP-Seq_THP-1_Human1.75271561
32NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.75040917
33RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.74841930
34* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.73964947
35MYC_18555785_ChIP-Seq_MESCs_Mouse1.72090790
36MYB_26560356_Chip-Seq_TH2_Human1.71089280
37RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.69416224
38FOXM1_23109430_ChIP-Seq_U2OS_Human1.69377683
39RUNX1_22412390_ChIP-Seq_EML_Mouse1.66189516
40NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.65908436
41GATA1_22025678_ChIP-Seq_K562_Human1.61720947
42KDM2B_26808549_Chip-Seq_SUP-B15_Human1.56795130
43GATA1_22383799_ChIP-Seq_G1ME_Mouse1.55655389
44SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.54190931
45E2F4_17652178_ChIP-ChIP_JURKAT_Human1.53343782
46STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.49703759
47VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.47005795
48* ELK3_25401928_ChIP-Seq_HUVEC_Human1.44179120
49LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.43389492
50* GABP_17652178_ChIP-ChIP_JURKAT_Human1.42351482
51LXR_22292898_ChIP-Seq_THP-1_Human1.41609394
52EST1_17652178_ChIP-ChIP_JURKAT_Human1.39954454
53* MYB_26560356_Chip-Seq_TH1_Human1.39659951
54CREB1_15753290_ChIP-ChIP_HEK293T_Human1.38865191
55* UTX_26944678_Chip-Seq_JUKART_Human1.36754020
56ERG_20887958_ChIP-Seq_HPC-7_Mouse1.36672995
57TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.36093198
58FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.35105924
59MYC_18358816_ChIP-ChIP_MESCs_Mouse1.34310500
60* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.33274940
61* VDR_23849224_ChIP-Seq_CD4+_Human1.32772542
62GATA2_21666600_ChIP-Seq_HMVEC_Human1.31708175
63CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.30952055
64MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.29941398
65E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.29933321
66HOXB4_20404135_ChIP-ChIP_EML_Mouse1.29503777
67PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.28426861
68TFEB_21752829_ChIP-Seq_HELA_Human1.28062404
69* ETS1_20019798_ChIP-Seq_JURKAT_Human1.27699470
70* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.26041111
71* MAF_26560356_Chip-Seq_TH2_Human1.25480907
72TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.24547696
73SPI1_23127762_ChIP-Seq_K562_Human1.24248882
74VDR_24787735_ChIP-Seq_THP-1_Human1.24165601
75* XRN2_22483619_ChIP-Seq_HELA_Human1.22840904
76BCL6_27268052_Chip-Seq_Bcells_Human1.21832287
77* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.20903915
78CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.20807711
79GATA2_22383799_ChIP-Seq_G1ME_Mouse1.20202912
80MYC_19079543_ChIP-ChIP_MESCs_Mouse1.19472628
81CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.19397200
82SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.18640554
83Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.18615487
84DCP1A_22483619_ChIP-Seq_HELA_Human1.16954900
85ELF1_20517297_ChIP-Seq_JURKAT_Human1.16297596
86RUNX_20019798_ChIP-Seq_JUKART_Human1.16160879
87RARG_19884340_ChIP-ChIP_MEFs_Mouse1.15544703
88STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.14981834
89TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.14875931
90GATA3_26560356_Chip-Seq_TH2_Human1.14612522
91BCOR_27268052_Chip-Seq_Bcells_Human1.14158178
92TCF7_22412390_ChIP-Seq_EML_Mouse1.13142101
93CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.12893955
94KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.12578146
95* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.11477694
96FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.10729469
97LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.10724430
98MYC_19030024_ChIP-ChIP_MESCs_Mouse1.10665226
99NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.10449564
100PU.1_20513432_ChIP-Seq_Bcells_Mouse1.09116713
101* GATA1_19941827_ChIP-Seq_MEL_Mouse1.07364317
102NCOR1_26117541_ChIP-Seq_K562_Human1.06937771
103SMAD_19615063_ChIP-ChIP_OVARY_Human1.06732908
104GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.06683641
105PU_27001747_Chip-Seq_BMDM_Mouse1.05221213
106HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.05098031
107THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.04188545
108STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.04082844
109E2F1_18555785_ChIP-Seq_MESCs_Mouse1.03375173
110CIITA_25753668_ChIP-Seq_RAJI_Human1.02019806
111CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.01067689
112PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.00624254
113KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.99432685
114GATA3_27048872_Chip-Seq_THYMUS_Human0.99070569
115GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.98890562
116CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.97519915
117SRF_21415370_ChIP-Seq_HL-1_Mouse0.97108477
118PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97003209
119FOXP3_21729870_ChIP-Seq_TREG_Human0.96340279
120* CTCF_27219007_Chip-Seq_ERYTHROID_Human0.96070528
121STAT6_21828071_ChIP-Seq_BEAS2B_Human0.95926608
122E2F1_21310950_ChIP-Seq_MCF-7_Human0.93482453
123KDM2B_26808549_Chip-Seq_DND41_Human0.90270522
124GATA1_19941826_ChIP-Seq_K562_Human0.90098731
125SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88576862
126GATA2_19941826_ChIP-Seq_K562_Human0.83869763
127* KDM2B_26808549_Chip-Seq_JURKAT_Human0.83572049
128* CTCF_26484167_Chip-Seq_Bcells_Mouse0.82040417
129GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81874238

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.93284889
2MP0000685_abnormal_immune_system3.06298651
3MP0003436_decreased_susceptibility_to2.82331935
4MP0005671_abnormal_response_to2.61524834
5MP0009785_altered_susceptibility_to2.61303299
6MP0002148_abnormal_hypersensitivity_rea2.60487948
7MP0005000_abnormal_immune_tolerance2.58628991
8MP0001790_abnormal_immune_system2.50893693
9MP0005387_immune_system_phenotype2.50893693
10MP0005025_abnormal_response_to2.43757764
11MP0003303_peritoneal_inflammation2.42065554
12MP0002419_abnormal_innate_immunity2.38503957
13MP0002452_abnormal_antigen_presenting2.38499901
14MP0006054_spinal_hemorrhage2.36508871
15MP0001800_abnormal_humoral_immune2.33840613
16MP0005058_abnormal_lysosome_morphology2.29282990
17MP0006082_CNS_inflammation2.22922353
18MP0002723_abnormal_immune_serum2.21999075
19MP0003656_abnormal_erythrocyte_physiolo2.18422141
20MP0002420_abnormal_adaptive_immunity2.14641968
21MP0001819_abnormal_immune_cell2.14574679
22MP0009333_abnormal_splenocyte_physiolog2.13334391
23MP0003724_increased_susceptibility_to2.12178140
24MP0001545_abnormal_hematopoietic_system2.07475011
25MP0005397_hematopoietic_system_phenotyp2.07475011
26MP0002396_abnormal_hematopoietic_system2.06370826
27MP0002405_respiratory_system_inflammati1.96482008
28MP0002398_abnormal_bone_marrow1.94610163
29MP0001853_heart_inflammation1.82265451
30MP0002166_altered_tumor_susceptibility1.78043851
31MP0000716_abnormal_immune_system1.78001768
32MP0005464_abnormal_platelet_physiology1.69616167
33MP0004947_skin_inflammation1.69176712
34MP0000689_abnormal_spleen_morphology1.68438504
35MP0003763_abnormal_thymus_physiology1.65270879
36MP0001533_abnormal_skeleton_physiology1.64876168
37MP0002722_abnormal_immune_system1.63288243
38MP0002429_abnormal_blood_cell1.61669852
39MP0008260_abnormal_autophagy1.58541519
40MP0010155_abnormal_intestine_physiology1.52833615
41MP0002006_tumorigenesis1.51191819
42MP0001845_abnormal_inflammatory_respons1.50359448
43MP0000858_altered_metastatic_potential1.49640937
44MP0000490_abnormal_crypts_of1.49452191
45MP0003300_gastrointestinal_ulcer1.47734590
46MP0010352_gastrointestinal_tract_polyps1.46322734
47MP0003172_abnormal_lysosome_physiology1.42847273
48MP0004510_myositis1.42821773
49MP0009278_abnormal_bone_marrow1.41521340
50MP0003448_altered_tumor_morphology1.40906263
51MP0004147_increased_porphyrin_level1.40194845
52MP0009840_abnormal_foam_cell1.40041473
53MP0000343_altered_response_to1.39466329
54MP0005310_abnormal_salivary_gland1.37900987
55MP0008438_abnormal_cutaneous_collagen1.34005776
56MP0003693_abnormal_embryo_hatching1.31220203
57MP0000465_gastrointestinal_hemorrhage1.29448136
58MP0002132_abnormal_respiratory_system1.28999983
59MP0008469_abnormal_protein_level1.26153110
60MP0005451_abnormal_body_composition1.26105134
61MP0001873_stomach_inflammation1.25735842
62MP0002877_abnormal_melanocyte_morpholog1.22513914
63MP0003279_aneurysm1.21401843
64MP0010307_abnormal_tumor_latency1.18159085
65MP0008007_abnormal_cellular_replicative1.17203063
66MP0004808_abnormal_hematopoietic_stem1.15229207
67MP0003186_abnormal_redox_activity1.14491037
68MP0003566_abnormal_cell_adhesion1.14042614
69MP0000703_abnormal_thymus_morphology1.12096654
70MP0002933_joint_inflammation1.11203832
71MP0005174_abnormal_tail_pigmentation1.10131369
72MP0008057_abnormal_DNA_replication1.07650870
73MP0003191_abnormal_cellular_cholesterol1.07537897
74MP0009764_decreased_sensitivity_to1.06811793
75MP0003077_abnormal_cell_cycle1.05063515
76MP0005166_decreased_susceptibility_to1.04980250
77MP0004957_abnormal_blastocyst_morpholog1.04851612
78MP0005023_abnormal_wound_healing1.01905562
79MP0008004_abnormal_stomach_pH1.01224623
80MP0003111_abnormal_nucleus_morphology1.00922119
81MP0003806_abnormal_nucleotide_metabolis1.00172340
82MP0003866_abnormal_defecation0.98469787
83MP0004883_abnormal_blood_vessel0.98282940
84MP0002019_abnormal_tumor_incidence0.97574532
85MP0003091_abnormal_cell_migration0.96245852
86MP0002998_abnormal_bone_remodeling0.95171505
87MP0003453_abnormal_keratinocyte_physiol0.93757313
88MP0003075_altered_response_to0.93111367
89MP0001851_eye_inflammation0.92487582
90MP0000249_abnormal_blood_vessel0.91776552
91MP0001958_emphysema0.91045398
92MP0010094_abnormal_chromosome_stability0.88516264
93MP0001243_abnormal_dermal_layer0.84880610
94MP0005167_abnormal_blood-brain_barrier0.82762379
95MP0005390_skeleton_phenotype0.82519630
96MP0003183_abnormal_peptide_metabolism0.80902844
97MP0001542_abnormal_bone_strength0.80346070
98MP0002138_abnormal_hepatobiliary_system0.78719016
99MP0002254_reproductive_system_inflammat0.77300603
100MP0009765_abnormal_xenobiotic_induced0.76561488
101MP0000604_amyloidosis0.74069013
102MP0005165_increased_susceptibility_to0.70906772
103MP0003705_abnormal_hypodermis_morpholog0.70824286
104MP0000313_abnormal_cell_death0.70086075
105MP0003828_pulmonary_edema0.69672081
106MP0009931_abnormal_skin_appearance0.69572026
107MP0000920_abnormal_myelination0.68903696
108MP0001663_abnormal_digestive_system0.66147744
109MP0009763_increased_sensitivity_to0.66051203
110MP0003795_abnormal_bone_structure0.65856389
111MP0001915_intracranial_hemorrhage0.65391738
112MP0002277_abnormal_respiratory_mucosa0.64845239
113MP0002095_abnormal_skin_pigmentation0.64512509
114MP0005076_abnormal_cell_differentiation0.64375029
115MP0002139_abnormal_hepatobiliary_system0.64242457
116MP0005164_abnormal_response_to0.64107787
117MP0002136_abnormal_kidney_physiology0.63667173
118MP0004381_abnormal_hair_follicle0.60692192
119MP0000767_abnormal_smooth_muscle0.60541008
120MP0005075_abnormal_melanosome_morpholog0.59385030
121MP0008874_decreased_physiological_sensi0.59223592
122MP0000609_abnormal_liver_physiology0.57310560

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)5.07845484
2Eczematoid dermatitis (HP:0000976)4.62282352
3Recurrent bacterial skin infections (HP:0005406)4.53998948
4Chronic otitis media (HP:0000389)4.17347821
5Elevated erythrocyte sedimentation rate (HP:0003565)4.04775219
6Petechiae (HP:0000967)3.99542957
7Abnormality of the heme biosynthetic pathway (HP:0010472)3.94006367
8Vacuolated lymphocytes (HP:0001922)3.91695570
9Abnormality of macrophages (HP:0004311)3.89087932
10Abnormal number of erythroid precursors (HP:0012131)3.88190632
11Increased cerebral lipofuscin (HP:0011813)3.81867182
12Abnormality of cells of the erythroid lineage (HP:0012130)3.79576202
13Increased neuronal autofluorescent lipopigment (HP:0002074)3.60131842
14Recurrent viral infections (HP:0004429)3.39383361
15Autoimmune thrombocytopenia (HP:0001973)3.30972974
16Cellulitis (HP:0100658)3.29063157
17Recurrent fungal infections (HP:0002841)3.25285976
18Recurrent skin infections (HP:0001581)3.12222889
19Myositis (HP:0100614)3.10270841
20Pulmonary infiltrates (HP:0002113)3.00922774
21Mediastinal lymphadenopathy (HP:0100721)2.98594891
22Pustule (HP:0200039)2.90890415
23Gastrointestinal infarctions (HP:0005244)2.84452749
24Interstitial pulmonary disease (HP:0006530)2.83359974
25Encephalitis (HP:0002383)2.77410194
26Poor head control (HP:0002421)2.76081772
27Thrombocytosis (HP:0001894)2.74998203
28Systemic lupus erythematosus (HP:0002725)2.69618788
29Hemoptysis (HP:0002105)2.68893329
30Nasal polyposis (HP:0100582)2.68251680
31Recurrent gram-negative bacterial infections (HP:0005420)2.65468753
32IgM deficiency (HP:0002850)2.64668718
33Abnormality of liposaccharide metabolism (HP:0010968)2.64595692
34Abnormality of glycosphingolipid metabolism (HP:0004343)2.64595692
35Abnormality of glycolipid metabolism (HP:0010969)2.64595692
36Recurrent bronchitis (HP:0002837)2.60366682
37Abnormality of the nasal mucosa (HP:0000433)2.60010344
38Reticulocytopenia (HP:0001896)2.57634237
39Chronic obstructive pulmonary disease (HP:0006510)2.56807570
40Obstructive lung disease (HP:0006536)2.56807570
41Dysostosis multiplex (HP:0000943)2.54064452
42Basal ganglia calcification (HP:0002135)2.52702854
43Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.52674102
44Orchitis (HP:0100796)2.51726599
45Chronic diarrhea (HP:0002028)2.50189999
46Vasculitis (HP:0002633)2.49040730
47Abnormality of T cell physiology (HP:0011840)2.48068423
48Pallor (HP:0000980)2.47211365
49Keratoconjunctivitis sicca (HP:0001097)2.45724766
50Increased serum ferritin (HP:0003281)2.45489197
51Stomatitis (HP:0010280)2.45323781
52Abnormality of mucopolysaccharide metabolism (HP:0011020)2.45295981
53Abnormality of polysaccharide metabolism (HP:0011012)2.45295981
54Abnormality of glycosaminoglycan metabolism (HP:0004371)2.45295981
55Loss of speech (HP:0002371)2.43118536
56Chronic mucocutaneous candidiasis (HP:0002728)2.39637639
57Recurrent cutaneous fungal infections (HP:0011370)2.39637639
58Hepatosplenomegaly (HP:0001433)2.37303969
59Vertebral compression fractures (HP:0002953)2.36980759
60Hypergammaglobulinemia (HP:0010702)2.34825135
61Leukocytosis (HP:0001974)2.34727212
62Urticaria (HP:0001025)2.34135831
63Osteolytic defects of the phalanges of the hand (HP:0009771)2.30142657
64Osteolytic defects of the hand bones (HP:0009699)2.30142657
65Agammaglobulinemia (HP:0004432)2.29925473
66Axonal loss (HP:0003447)2.28895368
67Hematochezia (HP:0002573)2.28031108
68Meningitis (HP:0001287)2.26650228
69Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.26073538
70Inflammation of the large intestine (HP:0002037)2.24881387
71Gingivitis (HP:0000230)2.23349945
72Abnormality of T cells (HP:0002843)2.22760206
73Gastrointestinal inflammation (HP:0004386)2.21858001
74Increased IgE level (HP:0003212)2.21708778
75Keratoconjunctivitis (HP:0001096)2.20487454
76Chest pain (HP:0100749)2.18263955
77Colitis (HP:0002583)2.16277313
78Prolonged bleeding time (HP:0003010)2.15626420
79Spontaneous hematomas (HP:0007420)2.14222867
80Osteomyelitis (HP:0002754)2.13894594
81Gingival bleeding (HP:0000225)2.13070416
82Hypertensive crisis (HP:0100735)2.11910605
83Recurrent pneumonia (HP:0006532)2.11394294
84Polycythemia (HP:0001901)2.11182827
85Recurrent lower respiratory tract infections (HP:0002783)2.11024273
86Retrobulbar optic neuritis (HP:0100654)2.09725192
87Optic neuritis (HP:0100653)2.09725192
88Agnosia (HP:0010524)2.09361571
89Skin ulcer (HP:0200042)2.09023803
90Glomerulopathy (HP:0100820)2.08248991
91Emphysema (HP:0002097)2.07111391
92Increased IgM level (HP:0003496)2.07017429
93Periodontitis (HP:0000704)2.05392277
94Restrictive lung disease (HP:0002091)2.04330190
95Gastrointestinal stroma tumor (HP:0100723)2.04049966
96Abnormality of cells of the lymphoid lineage (HP:0012140)2.03778407
97Pulmonary embolism (HP:0002204)2.02519753
98Lymphopenia (HP:0001888)2.01509711
99Abnormality of eosinophils (HP:0001879)2.01044633
100Amyloidosis (HP:0011034)2.00967409
101Epistaxis (HP:0000421)2.00676920
102Eosinophilia (HP:0001880)1.99901852
103Abnormal delayed hypersensitivity skin test (HP:0002963)1.99886322
104IgA deficiency (HP:0002720)1.98797193
105Panhypogammaglobulinemia (HP:0003139)1.98391891
106Abnormality of T cell number (HP:0011839)1.97639961
107Abnormality of reticulocytes (HP:0004312)1.97095407
108Purpura (HP:0000979)1.96534081
109Progressive neurologic deterioration (HP:0002344)1.96400958
110Severe combined immunodeficiency (HP:0004430)1.96089127
111Mucopolysacchariduria (HP:0008155)1.95890471
112Urinary glycosaminoglycan excretion (HP:0003541)1.95890471
113Arterial thrombosis (HP:0004420)1.95663359
114Joint swelling (HP:0001386)1.94681356
115Granulocytopenia (HP:0001913)1.91925595
116Abnormality of iron homeostasis (HP:0011031)1.88873809
117Abnormal platelet function (HP:0011869)1.85242172
118Impaired platelet aggregation (HP:0003540)1.85242172
119Fatigue (HP:0012378)1.84142992
120T lymphocytopenia (HP:0005403)1.83750152
121IgG deficiency (HP:0004315)1.83438816
122Combined immunodeficiency (HP:0005387)1.82526841
123Albinism (HP:0001022)1.82126819
124Autoimmune hemolytic anemia (HP:0001890)1.82026427

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K13.32892514
2BLK3.02174709
3NME22.96637078
4PRPF4B2.92297155
5PIM22.77032152
6TBK12.66813278
7TYK22.63668333
8MAP3K142.25849364
9TESK22.19739783
10STK102.15417592
11IRAK42.14129958
12ERN12.05984104
13JAK32.00147124
14KIT1.98848065
15IKBKB1.95857546
16IKBKE1.84694314
17LRRK21.82167707
18KDR1.77386551
19MST41.76938814
20ZAP701.70101682
21TAOK21.65652048
22TRIB31.62408950
23EIF2AK11.61097974
24CLK11.58092362
25EPHB11.54957290
26RPS6KA41.54828218
27CSF1R1.49007316
28BTK1.47962474
29BUB11.47141604
30IRAK31.46421925
31TGFBR21.46068950
32PBK1.45625085
33SCYL21.40318253
34STK161.34553402
35PIM11.29806009
36STK41.27430038
37SIK31.26793351
38MAP3K101.20656679
39FGR1.20622460
40JAK11.18813330
41SYK1.18806191
42TXK1.16324300
43PAK41.11939758
44TESK11.11450073
45MAP3K111.10281619
46TIE11.08712902
47GRK71.06126474
48WEE11.03910187
49LYN1.03889675
50MAP2K31.02882027
51CHUK1.00317779
52CSK0.99316398
53TEC0.98750093
54MAP3K80.97023959
55MAP3K10.94572364
56CAMKK20.93154615
57GRK60.93112754
58PRKG20.92889298
59TNK20.91121945
60LCK0.90488043
61EIF2AK30.89953180
62NEK20.87204974
63CDC42BPA0.86488585
64RIPK40.85632626
65EEF2K0.85086157
66TAOK10.85040895
67HCK0.85012321
68MAP3K130.84982803
69ITK0.82751688
70JAK20.82451043
71TLK10.81831628
72NEK90.81565497
73BRSK20.81144560
74MAP3K30.79612862
75SMG10.79458375
76TRPM70.76259695
77DYRK30.73353106
78SIK20.70763397
79PRKCQ0.69527467
80MATK0.68923737
81ILK0.65871833
82CDK40.65051154
83VRK10.64893839
84MAPK70.62657576
85MARK30.62206984
86PDK10.62179680
87ARAF0.61601343
88MAPKAPK20.60488522
89KSR20.60087390
90FLT30.59470760
91SIK10.58961700
92PKN20.58725532
93NLK0.58336178
94RPS6KA50.58092381
95BMX0.57829746
96ABL20.56053731
97RPS6KB20.55826276
98FGFR40.55717839
99IRAK10.55636578
100PDPK10.54257212
101PRKD20.54088476
102MAPK110.54061891
103BMPR20.53610923
104PIK3CG0.52318606
105TAOK30.51939484
106PAK10.51781102
107RAF10.51730351
108DYRK1B0.48966736
109RIPK10.47489207
110CDK60.47008176
111PTK60.46701732
112PRKCD0.46214420
113CDC70.46182659
114MAP2K20.45292558
115RPS6KC10.44884958
116RPS6KL10.44884958
117MAPKAPK50.42909528
118AURKB0.42712449
119MAPK120.41788710
120TTN0.41063042
121FYN0.40539574
122CAMKK10.38607081
123RPS6KA60.38435280
124MARK20.38275645
125MAP3K50.37706175
126ABL10.37131303
127TGFBR10.36854954
128FES0.36096970
129CDK70.35433272
130MOS0.34500015
131HIPK20.33989683
132EPHA30.32794792
133MAP3K60.32576841
134EGFR0.31653375
135EIF2AK20.31352113
136RPS6KA20.31072458
137DDR20.30534552
138MAPKAPK30.30132985
139CDK190.28906499

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030302.64835238
2Leishmaniasis_Homo sapiens_hsa051402.45785115
3Ribosome_Homo sapiens_hsa030102.36541441
4Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.29188664
5NF-kappa B signaling pathway_Homo sapiens_hsa040642.09949207
6Primary immunodeficiency_Homo sapiens_hsa053402.00812102
7Antigen processing and presentation_Homo sapiens_hsa046121.98625376
8Measles_Homo sapiens_hsa051621.92515782
9Malaria_Homo sapiens_hsa051441.90981177
10Intestinal immune network for IgA production_Homo sapiens_hsa046721.85014021
11Toll-like receptor signaling pathway_Homo sapiens_hsa046201.85011574
12Other glycan degradation_Homo sapiens_hsa005111.83443834
13Proteasome_Homo sapiens_hsa030501.79588267
14Osteoclast differentiation_Homo sapiens_hsa043801.78338188
15Legionellosis_Homo sapiens_hsa051341.78128179
16Mismatch repair_Homo sapiens_hsa034301.75280775
17Lysosome_Homo sapiens_hsa041421.74518576
18Base excision repair_Homo sapiens_hsa034101.74093799
19Allograft rejection_Homo sapiens_hsa053301.72745992
20B cell receptor signaling pathway_Homo sapiens_hsa046621.62495974
21Herpes simplex infection_Homo sapiens_hsa051681.60759241
22Pertussis_Homo sapiens_hsa051331.60690330
23Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.59530709
24Graft-versus-host disease_Homo sapiens_hsa053321.58897233
25Hematopoietic cell lineage_Homo sapiens_hsa046401.54203079
26Apoptosis_Homo sapiens_hsa042101.52942524
27Shigellosis_Homo sapiens_hsa051311.52066923
28Tuberculosis_Homo sapiens_hsa051521.47263675
29Toxoplasmosis_Homo sapiens_hsa051451.46456618
30RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.44496444
31Glycosaminoglycan degradation_Homo sapiens_hsa005311.40514343
32Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.39108839
33Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.37596283
34Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.37271768
35Influenza A_Homo sapiens_hsa051641.36439983
36NOD-like receptor signaling pathway_Homo sapiens_hsa046211.35378208
37Staphylococcus aureus infection_Homo sapiens_hsa051501.31823721
38Asthma_Homo sapiens_hsa053101.29713720
39Jak-STAT signaling pathway_Homo sapiens_hsa046301.21539076
40Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.19517065
41Viral myocarditis_Homo sapiens_hsa054161.17996345
42Salmonella infection_Homo sapiens_hsa051321.16857698
43TNF signaling pathway_Homo sapiens_hsa046681.14973589
44Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.13942086
45Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.13287314
46Homologous recombination_Homo sapiens_hsa034401.10503460
47Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.10114836
48p53 signaling pathway_Homo sapiens_hsa041151.10097744
49Hepatitis B_Homo sapiens_hsa051611.09180681
50Nucleotide excision repair_Homo sapiens_hsa034201.08521787
51Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.07174365
52Pyrimidine metabolism_Homo sapiens_hsa002401.05333015
53Epstein-Barr virus infection_Homo sapiens_hsa051691.04613971
54Spliceosome_Homo sapiens_hsa030401.04307536
55Leukocyte transendothelial migration_Homo sapiens_hsa046701.03098311
56Phagosome_Homo sapiens_hsa041451.00480653
57Viral carcinogenesis_Homo sapiens_hsa052030.98492961
58Rheumatoid arthritis_Homo sapiens_hsa053230.98432915
59Chemokine signaling pathway_Homo sapiens_hsa040620.97763447
60RNA polymerase_Homo sapiens_hsa030200.95643664
61Small cell lung cancer_Homo sapiens_hsa052220.95458718
62Chronic myeloid leukemia_Homo sapiens_hsa052200.94459576
63Non-homologous end-joining_Homo sapiens_hsa034500.92078318
64Acute myeloid leukemia_Homo sapiens_hsa052210.92037990
65Autoimmune thyroid disease_Homo sapiens_hsa053200.89292854
66Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.89261166
67AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.87492031
68Cell cycle_Homo sapiens_hsa041100.86426464
69Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.81000773
70T cell receptor signaling pathway_Homo sapiens_hsa046600.80486941
71Pentose phosphate pathway_Homo sapiens_hsa000300.80425614
72Hepatitis C_Homo sapiens_hsa051600.77789040
73Pancreatic cancer_Homo sapiens_hsa052120.76235310
74Systemic lupus erythematosus_Homo sapiens_hsa053220.75315215
75Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.72462917
76Sulfur relay system_Homo sapiens_hsa041220.71072207
77Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.70878834
78Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.70281592
79HTLV-I infection_Homo sapiens_hsa051660.69463561
80Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.67881989
81Prion diseases_Homo sapiens_hsa050200.65550574
82Platelet activation_Homo sapiens_hsa046110.63751257
83Non-small cell lung cancer_Homo sapiens_hsa052230.63544404
84African trypanosomiasis_Homo sapiens_hsa051430.63019630
85Bladder cancer_Homo sapiens_hsa052190.61681577
86Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.61420493
87Sphingolipid metabolism_Homo sapiens_hsa006000.61394578
88Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.61317298
89Protein export_Homo sapiens_hsa030600.59389624
90SNARE interactions in vesicular transport_Homo sapiens_hsa041300.59318031
91Amoebiasis_Homo sapiens_hsa051460.58873380
92Transcriptional misregulation in cancer_Homo sapiens_hsa052020.58564242
93One carbon pool by folate_Homo sapiens_hsa006700.55424064
94Caffeine metabolism_Homo sapiens_hsa002320.51895849
95Endocytosis_Homo sapiens_hsa041440.49618202
96RNA transport_Homo sapiens_hsa030130.48323623
97Prolactin signaling pathway_Homo sapiens_hsa049170.47809921
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.46610680
99Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.46324310
100Neurotrophin signaling pathway_Homo sapiens_hsa047220.44673973
101Notch signaling pathway_Homo sapiens_hsa043300.41162406
102MicroRNAs in cancer_Homo sapiens_hsa052060.40187119
103Renin-angiotensin system_Homo sapiens_hsa046140.39616451
104N-Glycan biosynthesis_Homo sapiens_hsa005100.38926736
105Adipocytokine signaling pathway_Homo sapiens_hsa049200.37812375
106Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.37812363
107VEGF signaling pathway_Homo sapiens_hsa043700.36800875
108HIF-1 signaling pathway_Homo sapiens_hsa040660.36596292
109Complement and coagulation cascades_Homo sapiens_hsa046100.36570513
110Renal cell carcinoma_Homo sapiens_hsa052110.35467232
111Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.34743862
112RNA degradation_Homo sapiens_hsa030180.34539525
113Proteoglycans in cancer_Homo sapiens_hsa052050.33061329
114Fanconi anemia pathway_Homo sapiens_hsa034600.32345366
115Type I diabetes mellitus_Homo sapiens_hsa049400.32026083
116Phospholipase D signaling pathway_Homo sapiens_hsa040720.28725481
117Galactose metabolism_Homo sapiens_hsa000520.24670851
118Regulation of actin cytoskeleton_Homo sapiens_hsa048100.23201204
119MAPK signaling pathway_Homo sapiens_hsa040100.22097352
120FoxO signaling pathway_Homo sapiens_hsa040680.21246035
121Collecting duct acid secretion_Homo sapiens_hsa049660.17836518
122Dorso-ventral axis formation_Homo sapiens_hsa043200.15281317
123Regulation of autophagy_Homo sapiens_hsa041400.14755583
124Colorectal cancer_Homo sapiens_hsa052100.12409596
125mTOR signaling pathway_Homo sapiens_hsa041500.11856845
126Sulfur metabolism_Homo sapiens_hsa009200.11192929

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