NCR1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cellular response to interleukin-15 (GO:0071350)9.18706772
2activated T cell proliferation (GO:0050798)8.98806097
3response to interleukin-15 (GO:0070672)8.04339751
4negative regulation of cell killing (GO:0031342)7.37214227
5negative regulation of leukocyte mediated cytotoxicity (GO:0001911)7.37214227
6* cellular defense response (GO:0006968)6.43803513
7positive regulation of gamma-delta T cell activation (GO:0046645)6.14121855
8regulation of isotype switching to IgG isotypes (GO:0048302)5.98393739
9negative thymic T cell selection (GO:0045060)5.87485628
10* regulation of natural killer cell mediated immunity (GO:0002715)5.61013737
11* regulation of natural killer cell mediated cytotoxicity (GO:0042269)5.61013737
12antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.55457533
13positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)5.52864980
14positive regulation of natural killer cell mediated immunity (GO:0002717)5.52864980
15negative T cell selection (GO:0043383)5.37288163
16regulation of gamma-delta T cell differentiation (GO:0045586)5.35780097
17positive thymic T cell selection (GO:0045059)5.08343654
18T cell migration (GO:0072678)5.06176425
19positive regulation of isotype switching (GO:0045830)4.95592431
20negative regulation of T cell mediated immunity (GO:0002710)4.87812905
21regulation of hypersensitivity (GO:0002883)4.85380677
22substrate-dependent cell migration (GO:0006929)4.79845925
23positive regulation of leukocyte mediated cytotoxicity (GO:0001912)4.78855276
24regulation of gamma-delta T cell activation (GO:0046643)4.74617258
25* natural killer cell activation (GO:0030101)4.73620966
26T cell differentiation involved in immune response (GO:0002292)4.63530608
27alpha-beta T cell differentiation involved in immune response (GO:0002293)4.63530608
28alpha-beta T cell activation involved in immune response (GO:0002287)4.63530608
29thymic T cell selection (GO:0045061)4.62336969
30antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.60764618
31antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.60764618
32* regulation of leukocyte mediated cytotoxicity (GO:0001910)4.55641886
33positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)4.38561852
34leukocyte cell-cell adhesion (GO:0007159)4.33465651
35heterotypic cell-cell adhesion (GO:0034113)4.32173586
36positive regulation of cell killing (GO:0031343)4.30573562
37DNA deamination (GO:0045006)4.23143045
38T cell activation involved in immune response (GO:0002286)4.20622715
39positive regulation of DNA recombination (GO:0045911)4.15054640
40* regulation of cell killing (GO:0031341)4.09503676
41behavioral response to nicotine (GO:0035095)4.08904053
42hypotonic response (GO:0006971)4.08333655
43positive regulation of immunoglobulin mediated immune response (GO:0002891)4.07716805
44positive regulation of B cell mediated immunity (GO:0002714)4.07716805
45leukocyte aggregation (GO:0070486)4.06358416
46alpha-beta T cell activation (GO:0046631)3.94423609
47endoderm formation (GO:0001706)3.90614797
48T cell proliferation (GO:0042098)3.87873509
49antigen processing and presentation of endogenous antigen (GO:0019883)3.87294262
50lymphocyte migration (GO:0072676)3.78012618
51regulation of B cell receptor signaling pathway (GO:0050855)3.76117493
52alpha-beta T cell differentiation (GO:0046632)3.69894406
53regulation of alkaline phosphatase activity (GO:0010692)3.68601038
54positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.67739370
55regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.64423450
56regulation of B cell differentiation (GO:0045577)3.63393836
57regulation of response to interferon-gamma (GO:0060330)3.62259622
58mast cell activation (GO:0045576)3.62017799
59positive T cell selection (GO:0043368)3.60511249
60L-fucose catabolic process (GO:0042355)3.57033967
61fucose catabolic process (GO:0019317)3.57033967
62L-fucose metabolic process (GO:0042354)3.57033967
63regulation of lymphocyte chemotaxis (GO:1901623)3.53080997
64regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.51962334
65positive regulation of T cell mediated cytotoxicity (GO:0001916)3.51936374
66CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.51919188
67T-helper cell differentiation (GO:0042093)3.51919188
68T cell selection (GO:0045058)3.50325094
69positive regulation of lymphocyte mediated immunity (GO:0002708)3.50069733
70regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.49121927
71negative regulation of lymphocyte mediated immunity (GO:0002707)3.46408768
72skin morphogenesis (GO:0043589)3.44591950
73preassembly of GPI anchor in ER membrane (GO:0016254)3.41160556
74positive regulation of defense response to virus by host (GO:0002230)3.39466864
75leukocyte tethering or rolling (GO:0050901)3.38078651
76mast cell degranulation (GO:0043303)3.34955175
77mast cell activation involved in immune response (GO:0002279)3.34955175
78regulation of memory T cell differentiation (GO:0043380)3.34952076
79regulation of isotype switching (GO:0045191)3.31942745
80regulation of T cell mediated cytotoxicity (GO:0001914)3.29969316
81rRNA catabolic process (GO:0016075)3.29521741
82negative regulation of telomere maintenance (GO:0032205)3.28630402
83positive regulation of interferon-gamma production (GO:0032729)3.27978761
84negative regulation of oxidoreductase activity (GO:0051354)3.24807402
85T cell costimulation (GO:0031295)3.24292995
86negative regulation of interleukin-1 beta production (GO:0032691)3.22467789
87* regulation of lymphocyte mediated immunity (GO:0002706)3.21440105
88negative regulation of interleukin-1 production (GO:0032692)3.20961053
89lymphocyte costimulation (GO:0031294)3.16400731
90negative regulation of leukocyte mediated immunity (GO:0002704)3.15651154
91neutrophil activation (GO:0042119)3.14145317
92adaptation of signaling pathway (GO:0023058)3.12827078
93neutrophil activation involved in immune response (GO:0002283)3.10528378
94cytidine deamination (GO:0009972)3.10396729
95cytidine metabolic process (GO:0046087)3.10396729
96cytidine catabolic process (GO:0006216)3.10396729
97B cell receptor signaling pathway (GO:0050853)3.06621242
98positive regulation of T-helper 1 type immune response (GO:0002827)3.06066313
99T cell differentiation (GO:0030217)3.05659280
100regulation of acute inflammatory response to antigenic stimulus (GO:0002864)3.03548417
101negative regulation of mast cell activation (GO:0033004)3.02864719
102regulation of immunoglobulin mediated immune response (GO:0002889)3.02053851
103positive regulation of leukocyte mediated immunity (GO:0002705)3.01871103
104positive regulation of immunoglobulin production (GO:0002639)2.99922608
105growth hormone receptor signaling pathway (GO:0060396)2.99417799
106cell wall macromolecule metabolic process (GO:0044036)2.98104013
107response to protozoan (GO:0001562)2.95533604
108cell adhesion mediated by integrin (GO:0033627)2.95436712
109cortical actin cytoskeleton organization (GO:0030866)2.94819627
110regulation of mesoderm development (GO:2000380)2.94763919
111regulation of B cell mediated immunity (GO:0002712)2.93303260
112platelet dense granule organization (GO:0060155)2.92355303
113granulocyte activation (GO:0036230)2.92121018
114protein polyglutamylation (GO:0018095)2.89500001
115tolerance induction (GO:0002507)2.89227682
116kynurenine metabolic process (GO:0070189)2.86888058
117positive regulation of humoral immune response (GO:0002922)2.86522452
118indole-containing compound catabolic process (GO:0042436)2.86269425
119indolalkylamine catabolic process (GO:0046218)2.86269425
120tryptophan catabolic process (GO:0006569)2.86269425
121pyrimidine ribonucleoside catabolic process (GO:0046133)2.85407335
122T cell receptor signaling pathway (GO:0050852)2.83995443
123cellular extravasation (GO:0045123)2.83373637
124cell wall macromolecule catabolic process (GO:0016998)2.82738112
125dendritic cell chemotaxis (GO:0002407)2.80808452
126hepatocyte apoptotic process (GO:0097284)2.80588568
127* regulation of leukocyte mediated immunity (GO:0002703)2.80470376
128dendritic cell migration (GO:0036336)2.80236483
129sequestering of actin monomers (GO:0042989)2.79627744
130multicellular organism reproduction (GO:0032504)2.77874724
131chaperone-mediated protein transport (GO:0072321)2.75420488
132positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)2.74791756
133regulation of T-helper 1 type immune response (GO:0002825)2.74027198
134sulfation (GO:0051923)2.71313474
135protein-cofactor linkage (GO:0018065)2.70612358
136regulation of germinal center formation (GO:0002634)2.70028479
137establishment of protein localization to mitochondrial membrane (GO:0090151)2.68729403
138GPI anchor metabolic process (GO:0006505)2.67652007
139regulation of activation of Janus kinase activity (GO:0010533)2.64452675
140regulation of rhodopsin mediated signaling pathway (GO:0022400)2.61499942
141regulation of regulatory T cell differentiation (GO:0045589)2.60580108
142positive regulation of oligodendrocyte differentiation (GO:0048714)2.60241789
143head development (GO:0060322)2.58537211
144adenosine metabolic process (GO:0046085)2.57362648
145negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.56613276
146indolalkylamine metabolic process (GO:0006586)2.56315201
147neural tube formation (GO:0001841)2.56121217
148cellular ketone body metabolic process (GO:0046950)2.55321429
149sleep (GO:0030431)2.55050568
150water-soluble vitamin biosynthetic process (GO:0042364)2.52134331
151regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.51763860
152RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.50679861
153negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.49721653
154axoneme assembly (GO:0035082)2.46810349
155RNA destabilization (GO:0050779)2.46405543
156protein K11-linked deubiquitination (GO:0035871)2.45209851
157rhodopsin mediated signaling pathway (GO:0016056)2.44688052
158leukocyte degranulation (GO:0043299)2.40599951
159regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.40415681
160regulation of mitotic spindle checkpoint (GO:1903504)2.40415681
161regulation of alpha-beta T cell proliferation (GO:0046640)2.39956758
162regulation of DNA methylation (GO:0044030)2.39575067
163lysosome localization (GO:0032418)2.38995086
164neurofilament cytoskeleton organization (GO:0060052)2.38441940
165regulation of defense response to virus by host (GO:0050691)2.38348709
166negative regulation of T-helper cell differentiation (GO:0045623)2.37980262
167negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.37980262
168interferon-gamma production (GO:0032609)14.0488241
169cytolysis (GO:0019835)12.1141590

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse6.45059504
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human5.56115827
3STAT3_20064451_ChIP-Seq_CD4+T_Mouse4.52955463
4RUNX_20019798_ChIP-Seq_JUKART_Human4.23291011
5STAT4_19710469_ChIP-ChIP_TH1__Mouse3.85983956
6MYB_26560356_Chip-Seq_TH2_Human3.34135074
7NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.27481650
8FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.25912723
9IRF8_21731497_ChIP-ChIP_J774_Mouse3.17839591
10MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.15636100
11ZNF274_21170338_ChIP-Seq_K562_Hela3.07299160
12STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse3.05860824
13EGR1_19374776_ChIP-ChIP_THP-1_Human2.98171330
14RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.96848715
15STAT6_21828071_ChIP-Seq_BEAS2B_Human2.93442588
16MAF_26560356_Chip-Seq_TH1_Human2.84214146
17VDR_22108803_ChIP-Seq_LS180_Human2.78584717
18MYB_26560356_Chip-Seq_TH1_Human2.77159248
19MYC_22102868_ChIP-Seq_BL_Human2.71805416
20FLI1_27457419_Chip-Seq_LIVER_Mouse2.54644645
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.52431739
22MYB_21317192_ChIP-Seq_ERMYB_Mouse2.52267774
23IRF1_19129219_ChIP-ChIP_H3396_Human2.50477457
24BP1_19119308_ChIP-ChIP_Hs578T_Human2.48457780
25SMAD_19615063_ChIP-ChIP_OVARY_Human2.48098932
26UTX_26944678_Chip-Seq_JUKART_Human2.46461317
27IRF8_22096565_ChIP-ChIP_GC-B_Human2.44186082
28IRF8_27001747_Chip-Seq_BMDM_Mouse2.43971265
29HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.43463599
30TCF7_22412390_ChIP-Seq_EML_Mouse2.38811766
31VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.31567624
32NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.27004302
33GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.25394276
34VDR_21846776_ChIP-Seq_THP-1_Human2.23381894
35IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.22959865
36IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.17149260
37E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.07945421
38SCL_19346495_ChIP-Seq_HPC-7_Human2.07028587
39SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.06269092
40IGF1R_20145208_ChIP-Seq_DFB_Human2.04456324
41GATA3_27048872_Chip-Seq_THYMUS_Human2.01306692
42RUNX1_22412390_ChIP-Seq_EML_Mouse2.01228113
43ZFP57_27257070_Chip-Seq_ESCs_Mouse2.00803220
44KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.00064419
45GBX2_23144817_ChIP-Seq_PC3_Human1.99584722
46PCGF2_27294783_Chip-Seq_ESCs_Mouse1.98633834
47KDM2B_26808549_Chip-Seq_DND41_Human1.95955165
48EZH2_22144423_ChIP-Seq_EOC_Human1.90685264
49KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.90591202
50BRD4_27068464_Chip-Seq_AML-cells_Mouse1.87207639
51RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.83691288
52VDR_24763502_ChIP-Seq_THP-1_Human1.79370669
53EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.75296749
54KDM2B_26808549_Chip-Seq_SUP-B15_Human1.73490946
55TAF15_26573619_Chip-Seq_HEK293_Human1.71922299
56NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.70253435
57POU3F2_20337985_ChIP-ChIP_501MEL_Human1.69682490
58E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.69137105
59SPI1_23127762_ChIP-Seq_K562_Human1.67679432
60P300_19829295_ChIP-Seq_ESCs_Human1.61265742
61CTBP1_25329375_ChIP-Seq_LNCAP_Human1.60018481
62SPI1_23547873_ChIP-Seq_NB4_Human1.59072474
63SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.58739109
64TP53_22573176_ChIP-Seq_HFKS_Human1.56772859
65HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.55365780
66BCAT_22108803_ChIP-Seq_LS180_Human1.55154337
67ER_23166858_ChIP-Seq_MCF-7_Human1.55095787
68SUZ12_27294783_Chip-Seq_NPCs_Mouse1.52799195
69CTBP2_25329375_ChIP-Seq_LNCAP_Human1.50948079
70MAF_26560356_Chip-Seq_TH2_Human1.49566817
71CBP_20019798_ChIP-Seq_JUKART_Human1.48604424
72IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.48604424
73PCGF2_27294783_Chip-Seq_NPCs_Mouse1.48310484
74E2F7_22180533_ChIP-Seq_HELA_Human1.47742536
75NFE2_27457419_Chip-Seq_LIVER_Mouse1.47579383
76GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.47564578
77RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.46131218
78TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.45376949
79MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.44582889
80VDR_24787735_ChIP-Seq_THP-1_Human1.40856962
81FOXA1_25329375_ChIP-Seq_VCAP_Human1.37992115
82FOXA1_27270436_Chip-Seq_PROSTATE_Human1.37992115
83EZH2_27294783_Chip-Seq_NPCs_Mouse1.36784577
84KDM2B_26808549_Chip-Seq_JURKAT_Human1.36715650
85FUS_26573619_Chip-Seq_HEK293_Human1.36675253
86EWS_26573619_Chip-Seq_HEK293_Human1.35284701
87TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.34306501
88GATA1_19941826_ChIP-Seq_K562_Human1.31941385
89MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.31266948
90FOXO3_23340844_ChIP-Seq_DLD1_Human1.28839030
91ETV2_25802403_ChIP-Seq_MESCs_Mouse1.28230494
92PRDM14_20953172_ChIP-Seq_ESCs_Human1.27169154
93* GATA3_21878914_ChIP-Seq_MCF-7_Human1.27046377
94ELK3_25401928_ChIP-Seq_HUVEC_Human1.27013995
95CLOCK_20551151_ChIP-Seq_293T_Human1.26850577
96CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.26314114
97MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.26119095
98GATA2_19941826_ChIP-Seq_K562_Human1.25210360
99GATA3_26560356_Chip-Seq_TH2_Human1.23758350
100UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.22091222
101FOXA1_21572438_ChIP-Seq_LNCaP_Human1.21893610
102PU_27001747_Chip-Seq_BMDM_Mouse1.21408187
103CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.19937484
104NCOR1_26117541_ChIP-Seq_K562_Human1.19714751
105NANOG_20526341_ChIP-Seq_ESCs_Human1.19455180
106NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.18842345
107GATA2_22383799_ChIP-Seq_G1ME_Mouse1.18329873
108AUTS2_25519132_ChIP-Seq_293T-REX_Human1.16177022
109VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.15753174
110TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.15351598
111TCF4_23295773_ChIP-Seq_U87_Human1.14508878
112CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.14043447
113NOTCH1_21737748_ChIP-Seq_TLL_Human1.14026473
114CRX_20693478_ChIP-Seq_RETINA_Mouse1.13046935
115POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.12665637
116TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12665637
117SOX2_19829295_ChIP-Seq_ESCs_Human1.12341196
118NANOG_19829295_ChIP-Seq_ESCs_Human1.12341196
119MYC_18940864_ChIP-ChIP_HL60_Human1.11627818
120MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.11616347
121PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.11542738
122LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.10730711
123GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10507599
124* TCF4_22108803_ChIP-Seq_LS180_Human1.10234460
125GABP_17652178_ChIP-ChIP_JURKAT_Human1.10020251
126NCOR_22424771_ChIP-Seq_293T_Human1.09977237
127LXR_22292898_ChIP-Seq_THP-1_Human1.09828070
128RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.09368926
129SMAD4_21741376_ChIP-Seq_EPCs_Human1.09240602
130STAT3_23295773_ChIP-Seq_U87_Human1.09230059
131THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.08588109
132SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.08225239
133VDR_23849224_ChIP-Seq_CD4+_Human1.08217177
134FLI1_21867929_ChIP-Seq_TH2_Mouse1.08193326
135FOXH1_21741376_ChIP-Seq_EPCs_Human1.08190589
136EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.07927701
137AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.07346166
138FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.05586466
139TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.04927967
140SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04668118
141REST_21632747_ChIP-Seq_MESCs_Mouse1.04621531
142SALL1_21062744_ChIP-ChIP_HESCs_Human1.04055028
143SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.03949702
144BMI1_23680149_ChIP-Seq_NPCS_Mouse1.03618030
145HOXB7_26014856_ChIP-Seq_BT474_Human1.03471552
146RUNX2_22187159_ChIP-Seq_PCA_Human1.03281442
147AR_20517297_ChIP-Seq_VCAP_Human1.02630302
148PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02170926
149SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.01608768
150OCT4_21477851_ChIP-Seq_ESCs_Mouse1.01021958
151GATA2_21666600_ChIP-Seq_HMVEC_Human1.00572659
152ERA_21632823_ChIP-Seq_H3396_Human1.00204268
153FOXH1_21741376_ChIP-Seq_ESCs_Human1.00024624
154AR_25329375_ChIP-Seq_VCAP_Human0.99974301
155PPARA_22158963_ChIP-Seq_LIVER_Mouse0.99442980
156FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.99005600
157SMAD3_21741376_ChIP-Seq_EPCs_Human0.98536506
158GATA1_19941827_ChIP-Seq_MEL_Mouse0.98239355
159PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.97944700
160GATA3_26560356_Chip-Seq_TH1_Human0.97873987
161ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.92976066
162SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.92504098
163GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.92185657
164EGR1_19032775_ChIP-ChIP_M12_Human0.90545019
165LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.89859826
166ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.88592310
167Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.88323668
168GATA1_22383799_ChIP-Seq_G1ME_Mouse0.85514918
169KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.82859553
170RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81008753
171PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.80543064
172CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.77548696
173SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.77245935
174SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.74953418
175SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.74953418
176SPI1_20517297_ChIP-Seq_HL60_Human0.73269010
177CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.72245127
178KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.71755480
179ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.69553323
180PPAR_26484153_Chip-Seq_NCI-H1993_Human0.69369466
181RXR_22158963_ChIP-Seq_LIVER_Mouse0.69058020
182SA1_27219007_Chip-Seq_ERYTHROID_Human0.68142487
183WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.67606048
184GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.66975555
185CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.66514655
186SMRT_27268052_Chip-Seq_Bcells_Human0.65386299
187TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.64568893

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006082_CNS_inflammation6.90818606
2MP0005671_abnormal_response_to6.77695944
3MP0009785_altered_susceptibility_to3.85895266
4MP0003448_altered_tumor_morphology3.41754362
5MP0001835_abnormal_antigen_presentation3.38490858
6MP0008877_abnormal_DNA_methylation3.26118120
7MP0001800_abnormal_humoral_immune3.24029442
8MP0010307_abnormal_tumor_latency3.12289833
9MP0003787_abnormal_imprinting2.95964413
10* MP0005025_abnormal_response_to2.88166690
11MP0001986_abnormal_taste_sensitivity2.80624896
12MP0000858_altered_metastatic_potential2.79691721
13MP0002723_abnormal_immune_serum2.74312174
14MP0005000_abnormal_immune_tolerance2.73715543
15* MP0002420_abnormal_adaptive_immunity2.67264920
16MP0003195_calcinosis2.67212165
17* MP0001819_abnormal_immune_cell2.64217128
18MP0003950_abnormal_plasma_membrane2.55861110
19MP0002132_abnormal_respiratory_system2.53955280
20MP0003763_abnormal_thymus_physiology2.45753309
21MP0002452_abnormal_antigen_presenting2.39469718
22MP0001790_abnormal_immune_system2.33518515
23MP0005387_immune_system_phenotype2.33518515
24MP0000685_abnormal_immune_system2.26385951
25MP0006292_abnormal_olfactory_placode2.25063038
26MP0008995_early_reproductive_senescence2.24614647
27MP0001873_stomach_inflammation2.19675568
28MP0002006_tumorigenesis2.19125360
29MP0002398_abnormal_bone_marrow2.16800916
30MP0003878_abnormal_ear_physiology2.16708126
31MP0005377_hearing/vestibular/ear_phenot2.16708126
32MP0003300_gastrointestinal_ulcer2.03147904
33MP0002277_abnormal_respiratory_mucosa2.02709769
34MP0006072_abnormal_retinal_apoptosis2.02336947
35MP0002102_abnormal_ear_morphology1.99218218
36MP0009333_abnormal_splenocyte_physiolog1.98927310
37MP0003724_increased_susceptibility_to1.93755643
38MP0002405_respiratory_system_inflammati1.91395548
39* MP0000716_abnormal_immune_system1.90673721
40MP0010155_abnormal_intestine_physiology1.88621223
41MP0002722_abnormal_immune_system1.86719995
42MP0002419_abnormal_innate_immunity1.84270239
43MP0005551_abnormal_eye_electrophysiolog1.82351728
44MP0008872_abnormal_physiological_respon1.79905779
45MP0004142_abnormal_muscle_tone1.77026820
46MP0000689_abnormal_spleen_morphology1.76628028
47MP0002166_altered_tumor_susceptibility1.74817968
48MP0001845_abnormal_inflammatory_respons1.74412551
49MP0005464_abnormal_platelet_physiology1.74128045
50MP0001968_abnormal_touch/_nociception1.72498347
51MP0004947_skin_inflammation1.72369657
52MP0002837_dystrophic_cardiac_calcinosis1.72367503
53MP0002876_abnormal_thyroid_physiology1.70074536
54MP0008469_abnormal_protein_level1.66212833
55MP0002254_reproductive_system_inflammat1.65155667
56MP0000703_abnormal_thymus_morphology1.64751279
57MP0003866_abnormal_defecation1.60608654
58MP0003646_muscle_fatigue1.57153784
59MP0002148_abnormal_hypersensitivity_rea1.54879790
60MP0003436_decreased_susceptibility_to1.53172982
61MP0002736_abnormal_nociception_after1.52909924
62MP0003172_abnormal_lysosome_physiology1.51990952
63MP0004885_abnormal_endolymph1.50737160
64* MP0002429_abnormal_blood_cell1.50562949
65MP0005084_abnormal_gallbladder_morpholo1.46703975
66MP0000920_abnormal_myelination1.41575844
67MP0002653_abnormal_ependyma_morphology1.38468144
68MP0003303_peritoneal_inflammation1.38002503
69MP0001851_eye_inflammation1.36859649
70MP0002163_abnormal_gland_morphology1.36450139
71MP0008875_abnormal_xenobiotic_pharmacok1.33610824
72MP0005075_abnormal_melanosome_morpholog1.28425740
73MP0009763_increased_sensitivity_to1.27047252
74MP0003011_delayed_dark_adaptation1.26681411
75MP0004043_abnormal_pH_regulation1.24178554
76MP0003786_premature_aging1.23036463
77MP0004133_heterotaxia1.22407344
78MP0001919_abnormal_reproductive_system1.20491755
79MP0004510_myositis1.19280535
80MP0005379_endocrine/exocrine_gland_phen1.18034249
81MP0002933_joint_inflammation1.16024368
82MP0009384_cardiac_valve_regurgitation1.13401570
83MP0002638_abnormal_pupillary_reflex1.12823400
84MP0010352_gastrointestinal_tract_polyps1.12737010
85MP0005389_reproductive_system_phenotype1.12495859
86MP0002396_abnormal_hematopoietic_system1.11870474
87MP0000343_altered_response_to1.11693654
88MP0005253_abnormal_eye_physiology1.11412244
89MP0000427_abnormal_hair_cycle1.10030788
90MP0002019_abnormal_tumor_incidence1.08457506
91MP0001485_abnormal_pinna_reflex1.07085043
92MP0002928_abnormal_bile_duct1.05523483
93MP0001533_abnormal_skeleton_physiology1.05118111
94MP0004147_increased_porphyrin_level1.03037581
95MP0005174_abnormal_tail_pigmentation1.02647939
96MP0004381_abnormal_hair_follicle1.02294037
97MP0009745_abnormal_behavioral_response1.01732205
98MP0001501_abnormal_sleep_pattern1.01310433
99MP0003566_abnormal_cell_adhesion1.01191409
100MP0004742_abnormal_vestibular_system1.00577889
101MP0003121_genomic_imprinting0.98935234
102MP0002272_abnormal_nervous_system0.98927825
103MP0005166_decreased_susceptibility_to0.96744923
104MP0000465_gastrointestinal_hemorrhage0.96692987
105MP0009764_decreased_sensitivity_to0.96634728
106MP0000490_abnormal_crypts_of0.96567777
107MP0006276_abnormal_autonomic_nervous0.96262322
108MP0005645_abnormal_hypothalamus_physiol0.95068524
109MP0004145_abnormal_muscle_electrophysio0.94452206
110MP0002998_abnormal_bone_remodeling0.93538549
111MP0001984_abnormal_olfaction0.93280521
112MP0000569_abnormal_digit_pigmentation0.92053359
113MP0000604_amyloidosis0.89555117
114MP0001486_abnormal_startle_reflex0.89481682
115MP0003880_abnormal_central_pattern0.89290750
116MP0005310_abnormal_salivary_gland0.88365584
117MP0003252_abnormal_bile_duct0.87540072
118MP0000609_abnormal_liver_physiology0.85166889
119MP0004808_abnormal_hematopoietic_stem0.84552018
120MP0003329_amyloid_beta_deposits0.83062800
121MP0005646_abnormal_pituitary_gland0.80930156
122MP0008873_increased_physiological_sensi0.80824602
123MP0001545_abnormal_hematopoietic_system0.80684280
124MP0005397_hematopoietic_system_phenotyp0.80684280
125MP0003119_abnormal_digestive_system0.79693804
126MP0001119_abnormal_female_reproductive0.78252934
127MP0001853_heart_inflammation0.77966985
128MP0001324_abnormal_eye_pigmentation0.75515558
129MP0005319_abnormal_enzyme/_coenzyme0.75417807
130MP0003567_abnormal_fetal_cardiomyocyte0.72411272
131MP0003122_maternal_imprinting0.71532291
132MP0003638_abnormal_response/metabolism_0.69138652
133MP0003136_yellow_coat_color0.68725176
134MP0005195_abnormal_posterior_eye0.68690826
135MP0010329_abnormal_lipoprotein_level0.68548760
136MP0002557_abnormal_social/conspecific_i0.68369303
137MP0000631_abnormal_neuroendocrine_gland0.67474926
138MP0003690_abnormal_glial_cell0.64865310
139MP0004883_abnormal_blood_vessel0.64796880
140MP0003091_abnormal_cell_migration0.61501341
141MP0001727_abnormal_embryo_implantation0.61235421
142MP0004130_abnormal_muscle_cell0.58406728
143MP0008961_abnormal_basal_metabolism0.57868453
144MP0003075_altered_response_to0.57640785
145MP0003890_abnormal_embryonic-extraembry0.56766796
146MP0009278_abnormal_bone_marrow0.56728358
147MP0000249_abnormal_blood_vessel0.56478620
148MP0005023_abnormal_wound_healing0.53994091
149MP0005584_abnormal_enzyme/coenzyme_acti0.53684913
150MP0000613_abnormal_salivary_gland0.52227895
151MP0003453_abnormal_keratinocyte_physiol0.51390614
152MP0006054_spinal_hemorrhage0.51029059
153MP0002138_abnormal_hepatobiliary_system0.50244130
154MP0002693_abnormal_pancreas_physiology0.46777133
155MP0009840_abnormal_foam_cell0.45310211
156MP0002877_abnormal_melanocyte_morpholog0.42773802
157MP0003045_fibrosis0.42489015
158MP0001663_abnormal_digestive_system0.41971865
159MP0005360_urolithiasis0.41060802
160MP0002136_abnormal_kidney_physiology0.41007568
161MP0003705_abnormal_hypodermis_morpholog0.40877441
162MP0004924_abnormal_behavior0.39719325
163MP0005386_behavior/neurological_phenoty0.39719325
164MP0005076_abnormal_cell_differentiation0.39097761
165MP0002086_abnormal_extraembryonic_tissu0.37185746
166MP0009642_abnormal_blood_homeostasis0.36874685
167MP0008874_decreased_physiological_sensi0.35662019

Predicted human phenotypes

RankGene SetZ-score
1Hemiplegia (HP:0002301)8.36672072
2Hypoproteinemia (HP:0003075)7.57779498
3Optic neuritis (HP:0100653)6.85850927
4Retrobulbar optic neuritis (HP:0100654)6.85850927
5Encephalitis (HP:0002383)6.72974442
6Orchitis (HP:0100796)6.26767193
7Tetraplegia (HP:0002445)6.22160908
8Myositis (HP:0100614)6.11531203
9Abnormality of the common coagulation pathway (HP:0010990)5.90042804
10Increased serum ferritin (HP:0003281)5.75752662
11Nasal polyposis (HP:0100582)5.59788153
12Abnormality of macrophages (HP:0004311)5.51866044
13Increased CSF protein (HP:0002922)5.23170485
14Keratoconjunctivitis sicca (HP:0001097)4.96000955
15Abnormality of iron homeostasis (HP:0011031)4.91653727
16Abnormality of the nasal mucosa (HP:0000433)4.71514989
17Abnormal albumin level (HP:0012116)4.61444555
18Hypoalbuminemia (HP:0003073)4.61444555
19Meningitis (HP:0001287)4.58833899
20Keratoconjunctivitis (HP:0001096)4.46383662
21Joint swelling (HP:0001386)4.28022855
22Abnormality of transition element cation homeostasis (HP:0011030)4.20037250
23T lymphocytopenia (HP:0005403)4.02408208
24Stomatitis (HP:0010280)4.00971004
25Hyponatremia (HP:0002902)3.85991434
26Abnormality of T cell number (HP:0011839)3.75253590
27Congenital stationary night blindness (HP:0007642)3.70925830
28Pancreatic cysts (HP:0001737)3.64651019
29Spontaneous hematomas (HP:0007420)3.54908423
30IgG deficiency (HP:0004315)3.53646624
31Abnormality of intracranial pressure (HP:0012640)3.50268789
32Increased intracranial pressure (HP:0002516)3.50268789
33Arterial thrombosis (HP:0004420)3.48259629
34IgM deficiency (HP:0002850)3.45582528
35Pulmonary embolism (HP:0002204)3.42765112
36Renal cortical cysts (HP:0000803)3.38204785
37Stomach cancer (HP:0012126)3.33950621
38Molar tooth sign on MRI (HP:0002419)3.32121185
39Abnormality of midbrain morphology (HP:0002418)3.32121185
40Nephronophthisis (HP:0000090)3.25034876
41Abnormality of sodium homeostasis (HP:0010931)3.14968593
42Hypertriglyceridemia (HP:0002155)3.13776850
43Abnormality of the renal cortex (HP:0011035)3.11766559
44Abnormal rod and cone electroretinograms (HP:0008323)2.92687018
45Inflammation of the large intestine (HP:0002037)2.89663617
46Pancreatic fibrosis (HP:0100732)2.87550677
47Vasculitis (HP:0002633)2.87544132
48True hermaphroditism (HP:0010459)2.86318063
49Increased IgE level (HP:0003212)2.85086279
50Pulmonary infiltrates (HP:0002113)2.82407043
51Increased density of long bones (HP:0006392)2.80593478
52Abolished electroretinogram (ERG) (HP:0000550)2.80195333
53Gastrointestinal inflammation (HP:0004386)2.75797387
54Duplicated collecting system (HP:0000081)2.72987774
55Abnormality of the renal collecting system (HP:0004742)2.70068121
56Recurrent abscess formation (HP:0002722)2.65574420
57Abnormality of the renal medulla (HP:0100957)2.63981726
58Chronic hepatic failure (HP:0100626)2.63208526
59Absent rod-and cone-mediated responses on ERG (HP:0007688)2.54136933
60Hemoptysis (HP:0002105)2.52870733
61Bilateral sensorineural hearing impairment (HP:0008619)2.50726632
62Attenuation of retinal blood vessels (HP:0007843)2.50350021
63Hyperbilirubinemia (HP:0002904)2.47409468
64Gangrene (HP:0100758)2.47055170
65Abnormality of T cells (HP:0002843)2.46086626
66Abnormality of DNA repair (HP:0003254)2.45286833
67Lymphoma (HP:0002665)2.43110693
68Eczematoid dermatitis (HP:0000976)2.41183234
69Anorexia (HP:0002039)2.40469819
70Abnormality of B cell number (HP:0010975)2.36133026
71Chronic otitis media (HP:0000389)2.32718054
72Alveolar cell carcinoma (HP:0006519)2.32012850
73Recurrent fungal infections (HP:0002841)2.30901781
74Recurrent bronchitis (HP:0002837)2.28285036
75Pendular nystagmus (HP:0012043)2.26234925
76Interstitial pulmonary disease (HP:0006530)2.25502977
77Colitis (HP:0002583)2.25398619
78Aplasia/hypoplasia of the uterus (HP:0008684)2.24407149
79Hypoplasia of the uterus (HP:0000013)2.23656522
80Inability to walk (HP:0002540)2.22694361
81Aplasia/Hypoplasia of the spleen (HP:0010451)2.22624485
82Neoplasm of the tracheobronchial system (HP:0100552)2.22421105
83Abnormality of T cell physiology (HP:0011840)2.21143810
84Gingival bleeding (HP:0000225)2.17625239
85Recurrent viral infections (HP:0004429)2.17505436
86Abnormal delayed hypersensitivity skin test (HP:0002963)2.17330069
87Abnormal pancreas size (HP:0012094)2.16481190
88Abnormal biliary tract physiology (HP:0012439)2.14957193
89Bile duct proliferation (HP:0001408)2.14957193
90Progressive inability to walk (HP:0002505)2.14861269
91Asplenia (HP:0001746)2.14657686
92Gastrointestinal infarctions (HP:0005244)2.13627265
93Abnormal platelet volume (HP:0011876)2.12474346
94Recurrent gram-negative bacterial infections (HP:0005420)2.11806694
95Periodontitis (HP:0000704)2.10051552
96Medial flaring of the eyebrow (HP:0010747)2.06315293
97Prolonged bleeding time (HP:0003010)2.05028801
98Keratitis (HP:0000491)2.03580223
99Absent thumb (HP:0009777)2.02052719
100Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.00074110
101Abnormality of alanine metabolism (HP:0010916)2.00074110
102Hyperalaninemia (HP:0003348)2.00074110
103Brittle hair (HP:0002299)1.99464831
104Glomerulopathy (HP:0100820)1.98019058
105Increased IgM level (HP:0003496)1.97798608
106Leukocytosis (HP:0001974)1.97212918
107Concave nail (HP:0001598)1.95302488
108Chest pain (HP:0100749)1.95024138
109Arthralgia (HP:0002829)1.94393887
110Broad ribs (HP:0000885)1.94273838
111Combined immunodeficiency (HP:0005387)1.93701524
112Hypochromic anemia (HP:0001931)1.93464243
113Thrombophlebitis (HP:0004418)1.92274634
114Cystic liver disease (HP:0006706)1.91421297
115Verrucae (HP:0200043)1.91194493
116Papilloma (HP:0012740)1.91194493
117Aortic aneurysm (HP:0004942)1.90785731
118Epistaxis (HP:0000421)1.89824738
119Abnormality of oral frenula (HP:0000190)1.87786619
120Agitation (HP:0000713)1.87605775
121Intestinal atresia (HP:0011100)1.87081439
122Pustule (HP:0200039)1.86271773
123Aplasia/Hypoplasia of the uvula (HP:0010293)1.86049072
124Methylmalonic acidemia (HP:0002912)1.85124727
125Autoimmune thrombocytopenia (HP:0001973)1.84288747
126Thyroiditis (HP:0100646)1.83711161
127Type II lissencephaly (HP:0007260)1.83632313
128Abnormality of the pleura (HP:0002103)1.82614057
129Abnormality of the ileum (HP:0001549)1.80586831
130Chromosomal breakage induced by crosslinking agents (HP:0003221)1.80419232
131Striae distensae (HP:0001065)1.80238899
132Absent/shortened dynein arms (HP:0200106)1.80133191
133Dynein arm defect of respiratory motile cilia (HP:0012255)1.80133191
134Abnormality of eosinophils (HP:0001879)1.79690935
135Arterial tortuosity (HP:0005116)1.79166246
136Ectopic kidney (HP:0000086)1.79087981
137Cellulitis (HP:0100658)1.79070421
138Dysostosis multiplex (HP:0000943)1.78980255
139Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.78955074
140Meckel diverticulum (HP:0002245)1.78332859
141Elevated erythrocyte sedimentation rate (HP:0003565)1.78260775
142Obstructive lung disease (HP:0006536)1.78012690
143Chronic obstructive pulmonary disease (HP:0006510)1.78012690
144Eosinophilia (HP:0001880)1.76938375
145Conical tooth (HP:0000698)1.76866620
146Spondylolisthesis (HP:0003302)1.76746507
147Urinary glycosaminoglycan excretion (HP:0003541)1.76569811
148Mucopolysacchariduria (HP:0008155)1.76569811
149Decreased electroretinogram (ERG) amplitude (HP:0000654)1.76082428
150Oligodactyly (hands) (HP:0001180)1.75877706
151Septo-optic dysplasia (HP:0100842)1.75512439
152Abnormality of the pericardium (HP:0001697)1.75440543
153Leukopenia (HP:0001882)1.74889872
154Neutropenia (HP:0001875)1.74686596
155Polyneuropathy (HP:0001271)1.73596900
156Abnormal platelet function (HP:0011869)1.71960591
157Impaired platelet aggregation (HP:0003540)1.71960591
158Premature skin wrinkling (HP:0100678)1.70959714
159Chromsome breakage (HP:0040012)1.70763732
160Recurrent bacterial skin infections (HP:0005406)1.70582194
161Hyperglycinemia (HP:0002154)1.70285499
162Menorrhagia (HP:0000132)1.69637171
163Hypomagnesemia (HP:0002917)1.69536263
164Bony spicule pigmentary retinopathy (HP:0007737)1.69189507
165Anencephaly (HP:0002323)1.69015836
166Clubbing of toes (HP:0100760)1.68892001
167Abnormal drinking behavior (HP:0030082)1.68489814
168Polydipsia (HP:0001959)1.68489814
169Abnormality of pyrimidine metabolism (HP:0004353)1.68102826
170Increased mean platelet volume (HP:0011877)1.68036044
171Severe combined immunodeficiency (HP:0004430)1.66901668
172Persistence of primary teeth (HP:0006335)1.63476937
173Panhypogammaglobulinemia (HP:0003139)1.62899494
174Mediastinal lymphadenopathy (HP:0100721)1.56071236

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK7.94599856
2JAK14.46828096
3MAP4K13.56793788
4GRK73.47606483
5ITK2.94329801
6STK102.88470607
7FRK2.67423361
8EPHB12.66865317
9ACVR1B2.49727621
10MAP4K22.48861869
11JAK32.39410544
12TAOK32.09224796
13NUAK12.08064645
14GRK62.04984692
15FES2.02079546
16GRK11.97184682
17BMPR1B1.91772654
18ZAK1.91403937
19TLK11.89904114
20TRIB31.86649928
21TYK21.86574929
22WNK31.81631556
23RIPK11.79799513
24CSK1.75830943
25ADRBK21.71221658
26MAP3K101.69926733
27TRIM281.67164277
28MST41.60427136
29EEF2K1.58724177
30STK241.58064740
31MUSK1.57075255
32PINK11.51974168
33LRRK21.43318519
34MAPK131.42358410
35BCKDK1.41246036
36PRKCH1.40459193
37SIK31.40438943
38EPHA31.38863005
39LCK1.37303522
40TTN1.37228747
41PRKCQ1.35377556
42IRAK31.35002753
43CASK1.30306803
44TNK21.28534329
45WNK41.25665431
46BTK1.22912350
47ZAP701.21245846
48PIM11.19973567
49CDK41.16677416
50TNIK1.16612396
51DAPK21.13567534
52FGFR31.12230097
53MAP3K91.10049292
54MAP2K21.06566131
55CDK121.05585983
56SYK1.04845896
57FGFR40.98751194
58OXSR10.97294272
59MAP3K40.96368065
60KIT0.95872509
61TBK10.92239201
62SIK20.89600457
63ADRBK10.89334919
64BMX0.86882914
65TGFBR20.86715793
66ALK0.86458816
67IRAK40.84145215
68KDR0.84002979
69PKN20.83444852
70PTK60.82976288
71HCK0.82175504
72MAP2K60.78758215
73MARK30.77076676
74DMPK0.76915217
75JAK20.76072335
76GSK3A0.75930220
77PIK3CG0.75090569
78MAP3K20.74761805
79MATK0.71860595
80INSRR0.71690778
81ERN10.69567005
82HIPK20.68882697
83BLK0.67947209
84CDK190.63449260
85TRPM70.61351662
86MAP3K140.60712062
87IGF1R0.60443211
88CHUK0.59623088
89FGR0.59584000
90LYN0.59116380
91BCR0.58067710
92MELK0.56800478
93DYRK20.56507887
94PAK30.56256957
95CDK90.56243712
96MAPK120.56123064
97MAP3K70.55790005
98RET0.55782666
99RPS6KA40.55542915
100IKBKE0.54072391
101BMPR20.53165595
102CDK60.53114857
103TSSK60.48923009
104STK390.46704141
105PIK3CA0.46236584
106PDK10.44842142
107PRKG20.44341634
108PRKCG0.44297102
109PRKCE0.44277421
110EIF2AK20.43816362
111CSF1R0.42493953
112CLK10.42390905
113NLK0.40793648
114TEC0.40258573
115STK160.39686844
116FYN0.39615150
117NME10.38566748
118PDGFRB0.37537228
119MAP2K70.37339509
120NEK20.37107922
121SGK30.37102996
122NTRK30.36888546
123GRK50.36732729
124PAK40.35751390
125CDK80.34924651
126TGFBR10.34895642
127CAMK1G0.34092408
128INSR0.34085487
129NTRK20.33852747
130TIE10.32369457
131MAP3K80.32238660
132MARK10.32081977
133RIPK40.31576060
134SCYL20.31160332
135PRKACA0.29357264
136RPS6KA60.28892154
137PRKCZ0.28689004
138CSNK1A1L0.28595371
139DYRK30.28372832
140TYRO30.28048573
141CSNK1G20.27929320
142ABL10.27247409
143MAP2K10.27071077
144PLK20.25812907
145PHKG10.25590021
146PHKG20.25590021
147MKNK20.25039267
148MAPK40.25028863
149CAMK10.24744441
150MAPKAPK30.24573319
151PTK20.24343816
152CSNK1G30.23723900
153CAMK1D0.23484609
154MAP2K30.23321506
155TESK20.22690694
156IKBKB0.21980713
157CSNK1G10.21755869
158SIK10.21743371
159STK110.21087437
160ILK0.21079981

Predicted pathways (KEGG)

RankGene SetZ-score
1Graft-versus-host disease_Homo sapiens_hsa053327.97027109
2Allograft rejection_Homo sapiens_hsa053304.87699242
3* Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046504.74000865
4Type I diabetes mellitus_Homo sapiens_hsa049403.64302868
5Autoimmune thyroid disease_Homo sapiens_hsa053203.62401394
6Inflammatory bowel disease (IBD)_Homo sapiens_hsa053213.60658897
7Viral myocarditis_Homo sapiens_hsa054163.17164224
8Antigen processing and presentation_Homo sapiens_hsa046123.08446777
9Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.78415548
10Phototransduction_Homo sapiens_hsa047442.74762660
11alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.51850407
12Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.37576251
13Linoleic acid metabolism_Homo sapiens_hsa005912.36344832
14Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.25010358
15Staphylococcus aureus infection_Homo sapiens_hsa051502.02453175
16Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.82173320
17Malaria_Homo sapiens_hsa051441.81516692
18Leishmaniasis_Homo sapiens_hsa051401.67411286
19Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.66074420
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.61641095
21Maturity onset diabetes of the young_Homo sapiens_hsa049501.60407424
22B cell receptor signaling pathway_Homo sapiens_hsa046621.60015943
23Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.54309675
24Leukocyte transendothelial migration_Homo sapiens_hsa046701.53082771
25Ether lipid metabolism_Homo sapiens_hsa005651.52263272
26RNA polymerase_Homo sapiens_hsa030201.52211044
27Basal transcription factors_Homo sapiens_hsa030221.50365754
28T cell receptor signaling pathway_Homo sapiens_hsa046601.50274167
29Nicotine addiction_Homo sapiens_hsa050331.49942693
30Measles_Homo sapiens_hsa051621.47899456
31Butanoate metabolism_Homo sapiens_hsa006501.44894903
32Olfactory transduction_Homo sapiens_hsa047401.42509558
33Osteoclast differentiation_Homo sapiens_hsa043801.42208522
34Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.38908567
35Tryptophan metabolism_Homo sapiens_hsa003801.38150712
36Jak-STAT signaling pathway_Homo sapiens_hsa046301.36537477
37Toxoplasmosis_Homo sapiens_hsa051451.26633365
38Oxidative phosphorylation_Homo sapiens_hsa001901.25927740
39Primary immunodeficiency_Homo sapiens_hsa053401.23273506
40Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.22628962
41Selenocompound metabolism_Homo sapiens_hsa004501.22523032
42Apoptosis_Homo sapiens_hsa042101.22034843
43Morphine addiction_Homo sapiens_hsa050321.20284514
44Primary bile acid biosynthesis_Homo sapiens_hsa001201.20090011
45Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.18078681
46RNA degradation_Homo sapiens_hsa030181.14565190
47Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.13936892
48Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.13130414
49Fat digestion and absorption_Homo sapiens_hsa049751.10856136
50Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.09828743
51Platelet activation_Homo sapiens_hsa046111.09602613
52Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.08685123
53Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.07785735
54Fanconi anemia pathway_Homo sapiens_hsa034601.03342095
55Peroxisome_Homo sapiens_hsa041461.02087253
56Propanoate metabolism_Homo sapiens_hsa006400.99290343
57Arachidonic acid metabolism_Homo sapiens_hsa005900.98631717
58Shigellosis_Homo sapiens_hsa051310.97747384
59Protein export_Homo sapiens_hsa030600.97074500
60Chemokine signaling pathway_Homo sapiens_hsa040620.96646433
61Regulation of autophagy_Homo sapiens_hsa041400.96558920
62NF-kappa B signaling pathway_Homo sapiens_hsa040640.92921911
63Homologous recombination_Homo sapiens_hsa034400.91697848
64Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.88038908
65Pancreatic cancer_Homo sapiens_hsa052120.87604334
66Pertussis_Homo sapiens_hsa051330.87429079
67Asthma_Homo sapiens_hsa053100.85935369
68VEGF signaling pathway_Homo sapiens_hsa043700.85763863
69Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.84856158
70Collecting duct acid secretion_Homo sapiens_hsa049660.83165985
71Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.80731682
72Taste transduction_Homo sapiens_hsa047420.79936770
73Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.79815481
74TNF signaling pathway_Homo sapiens_hsa046680.78458883
75Vitamin digestion and absorption_Homo sapiens_hsa049770.77806583
76Regulation of actin cytoskeleton_Homo sapiens_hsa048100.77761541
77Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.77735816
78Retinol metabolism_Homo sapiens_hsa008300.76351948
79Acute myeloid leukemia_Homo sapiens_hsa052210.76194458
80AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.74982251
81Parkinsons disease_Homo sapiens_hsa050120.74468852
82Chemical carcinogenesis_Homo sapiens_hsa052040.73506955
83Steroid hormone biosynthesis_Homo sapiens_hsa001400.72463767
84Renal cell carcinoma_Homo sapiens_hsa052110.71056693
85Hepatitis B_Homo sapiens_hsa051610.71035585
86Tuberculosis_Homo sapiens_hsa051520.69707546
87Endocytosis_Homo sapiens_hsa041440.69607215
88Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.69565875
89Chronic myeloid leukemia_Homo sapiens_hsa052200.69505806
90Intestinal immune network for IgA production_Homo sapiens_hsa046720.68370917
91NOD-like receptor signaling pathway_Homo sapiens_hsa046210.67656695
92Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.67147535
93Colorectal cancer_Homo sapiens_hsa052100.65245193
94Salmonella infection_Homo sapiens_hsa051320.65228246
95HTLV-I infection_Homo sapiens_hsa051660.65219807
96Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.62484055
97Neurotrophin signaling pathway_Homo sapiens_hsa047220.62026360
98Caffeine metabolism_Homo sapiens_hsa002320.61632289
99Ovarian steroidogenesis_Homo sapiens_hsa049130.59364112
100Serotonergic synapse_Homo sapiens_hsa047260.58537365
101Hematopoietic cell lineage_Homo sapiens_hsa046400.57052258
102Legionellosis_Homo sapiens_hsa051340.57039022
103Glycerolipid metabolism_Homo sapiens_hsa005610.55839239
104Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.54402223
105Insulin secretion_Homo sapiens_hsa049110.54252882
106African trypanosomiasis_Homo sapiens_hsa051430.53332453
107Nitrogen metabolism_Homo sapiens_hsa009100.52697684
108Epstein-Barr virus infection_Homo sapiens_hsa051690.52117916
109Focal adhesion_Homo sapiens_hsa045100.50505017
110Non-small cell lung cancer_Homo sapiens_hsa052230.50324240
111Glycerophospholipid metabolism_Homo sapiens_hsa005640.48025969
112Circadian entrainment_Homo sapiens_hsa047130.47952369
113Sulfur metabolism_Homo sapiens_hsa009200.47092269
114Influenza A_Homo sapiens_hsa051640.46502076
115Gastric acid secretion_Homo sapiens_hsa049710.46411558
116Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.45133795
117Calcium signaling pathway_Homo sapiens_hsa040200.44887659
118Rap1 signaling pathway_Homo sapiens_hsa040150.44813037
119Toll-like receptor signaling pathway_Homo sapiens_hsa046200.43896622
120Purine metabolism_Homo sapiens_hsa002300.43023568
121Amoebiasis_Homo sapiens_hsa051460.41771820
122Carbohydrate digestion and absorption_Homo sapiens_hsa049730.41679348
123Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.41467662
124Transcriptional misregulation in cancer_Homo sapiens_hsa052020.41229788
125Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.40758330
126Sphingolipid signaling pathway_Homo sapiens_hsa040710.40087821
127Glycosaminoglycan degradation_Homo sapiens_hsa005310.39989280
128Small cell lung cancer_Homo sapiens_hsa052220.39570997
129ABC transporters_Homo sapiens_hsa020100.37914234
130Circadian rhythm_Homo sapiens_hsa047100.37391675
131Salivary secretion_Homo sapiens_hsa049700.36301394
132Prolactin signaling pathway_Homo sapiens_hsa049170.36012048
133Insulin resistance_Homo sapiens_hsa049310.35622462
134Rheumatoid arthritis_Homo sapiens_hsa053230.35572012
135Proteoglycans in cancer_Homo sapiens_hsa052050.34768730
136Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.34759756
137GABAergic synapse_Homo sapiens_hsa047270.34707651
138Hepatitis C_Homo sapiens_hsa051600.32944908
139SNARE interactions in vesicular transport_Homo sapiens_hsa041300.31672600
140Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.31506096
141Complement and coagulation cascades_Homo sapiens_hsa046100.31356964
142Estrogen signaling pathway_Homo sapiens_hsa049150.30768920
143Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.30491774
144Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.29604384
145Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.29155244
146RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.27663195
147Herpes simplex infection_Homo sapiens_hsa051680.27583391
148MAPK signaling pathway_Homo sapiens_hsa040100.27210106
149Viral carcinogenesis_Homo sapiens_hsa052030.26201457
150Long-term potentiation_Homo sapiens_hsa047200.25706574
151Phospholipase D signaling pathway_Homo sapiens_hsa040720.25443940
152Dilated cardiomyopathy_Homo sapiens_hsa054140.25242635
153Glioma_Homo sapiens_hsa052140.24196464
154FoxO signaling pathway_Homo sapiens_hsa040680.22964211
155cGMP-PKG signaling pathway_Homo sapiens_hsa040220.22216055
156mTOR signaling pathway_Homo sapiens_hsa041500.22135370
157Dorso-ventral axis formation_Homo sapiens_hsa043200.20460791
158HIF-1 signaling pathway_Homo sapiens_hsa040660.19162153
159Endometrial cancer_Homo sapiens_hsa052130.17081222
160Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.16759640
161Prion diseases_Homo sapiens_hsa050200.16032499
162Type II diabetes mellitus_Homo sapiens_hsa049300.15942808
163Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.14166445
164Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.13000052
165Renin secretion_Homo sapiens_hsa049240.12593450
166cAMP signaling pathway_Homo sapiens_hsa040240.11606188
167Oxytocin signaling pathway_Homo sapiens_hsa049210.11279797
168Adipocytokine signaling pathway_Homo sapiens_hsa049200.10965398

Most similar genes based on co-expression Upload to Enrichr

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