NCAPD3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPD3 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 [PubMed 14532007]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)6.22351212
2protein localization to kinetochore (GO:0034501)5.42901181
3* mitotic chromosome condensation (GO:0007076)5.29082531
4sister chromatid segregation (GO:0000819)5.03866061
5nuclear pore complex assembly (GO:0051292)5.01827164
6nuclear pore organization (GO:0006999)4.96067160
7DNA replication initiation (GO:0006270)4.91289562
8regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.88490959
9DNA strand elongation involved in DNA replication (GO:0006271)4.87488538
10mitotic sister chromatid segregation (GO:0000070)4.86005030
11mitotic sister chromatid cohesion (GO:0007064)4.82605843
12DNA replication-dependent nucleosome assembly (GO:0006335)4.74643168
13DNA replication-dependent nucleosome organization (GO:0034723)4.74643168
14protein localization to chromosome, centromeric region (GO:0071459)4.70478964
15kinetochore organization (GO:0051383)4.68790391
16DNA strand elongation (GO:0022616)4.63840674
17mitotic recombination (GO:0006312)4.63064411
18telomere maintenance via semi-conservative replication (GO:0032201)4.59692754
19attachment of spindle microtubules to kinetochore (GO:0008608)4.57510847
20chromatin remodeling at centromere (GO:0031055)4.43619078
21regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.42531325
22CENP-A containing nucleosome assembly (GO:0034080)4.40596895
23DNA topological change (GO:0006265)4.38590867
24meiotic chromosome segregation (GO:0045132)4.36163489
25telomere maintenance via recombination (GO:0000722)4.31097748
26DNA replication checkpoint (GO:0000076)4.25761474
27regulation of translational fidelity (GO:0006450)4.25698859
28mitotic nuclear envelope disassembly (GO:0007077)4.25674069
29DNA replication-independent nucleosome assembly (GO:0006336)4.18965517
30DNA replication-independent nucleosome organization (GO:0034724)4.18965517
31mitotic metaphase plate congression (GO:0007080)4.13081262
32DNA duplex unwinding (GO:0032508)4.08166524
33DNA geometric change (GO:0032392)4.07328732
34positive regulation of chromosome segregation (GO:0051984)4.01895845
35regulation of spindle organization (GO:0090224)3.99491025
36membrane disassembly (GO:0030397)3.97673410
37nuclear envelope disassembly (GO:0051081)3.97673410
38regulation of DNA endoreduplication (GO:0032875)3.95805785
39metaphase plate congression (GO:0051310)3.94434057
40nucleotide-excision repair, DNA gap filling (GO:0006297)3.89222533
41regulation of histone H3-K9 methylation (GO:0051570)3.87168291
42regulation of mitotic spindle organization (GO:0060236)3.84054359
43establishment of chromosome localization (GO:0051303)3.79801296
44pore complex assembly (GO:0046931)3.79588880
45translesion synthesis (GO:0019985)3.76484678
46histone exchange (GO:0043486)3.72174078
47chromatin assembly or disassembly (GO:0006333)3.71262649
48mismatch repair (GO:0006298)3.70616414
49telomere maintenance via telomere lengthening (GO:0010833)3.69730923
50kinetochore assembly (GO:0051382)3.62836131
51regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.61976676
52positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.60281232
53positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.60281232
54positive regulation of mitotic sister chromatid separation (GO:1901970)3.60281232
55IMP biosynthetic process (GO:0006188)3.59870360
56* DNA conformation change (GO:0071103)3.57628057
57establishment of integrated proviral latency (GO:0075713)3.57570076
58double-strand break repair via nonhomologous end joining (GO:0006303)3.57140994
59non-recombinational repair (GO:0000726)3.57140994
60protein localization to chromosome (GO:0034502)3.54821385
61chromosome segregation (GO:0007059)3.51509586
62regulation of sister chromatid cohesion (GO:0007063)3.51182895
63* chromosome condensation (GO:0030261)3.49759075
64regulation of chromosome segregation (GO:0051983)3.48581206
65negative regulation of histone methylation (GO:0031061)3.48012330
66regulation of RNA export from nucleus (GO:0046831)3.47084696
67formation of translation preinitiation complex (GO:0001731)3.45914615
68DNA synthesis involved in DNA repair (GO:0000731)3.45180421
69regulation of centriole replication (GO:0046599)3.42314266
70spindle checkpoint (GO:0031577)3.41224845
71spliceosomal tri-snRNP complex assembly (GO:0000244)3.40714634
72DNA ligation (GO:0006266)3.39644910
73chromatin assembly (GO:0031497)3.38260904
74telomere maintenance (GO:0000723)3.35821538
75heterochromatin organization (GO:0070828)3.35301329
76telomere organization (GO:0032200)3.33071980
77protein complex localization (GO:0031503)3.32918220
78regulation of centrosome cycle (GO:0046605)3.32762672
79postreplication repair (GO:0006301)3.31582968
80folic acid-containing compound biosynthetic process (GO:0009396)3.31320644
81* DNA packaging (GO:0006323)3.29743143
82ribosome assembly (GO:0042255)3.29048520
83regulation of mitotic metaphase/anaphase transition (GO:0030071)3.28449895
84spindle assembly checkpoint (GO:0071173)3.26536376
85ATP-dependent chromatin remodeling (GO:0043044)3.23683677
86V(D)J recombination (GO:0033151)3.23362832
87negative regulation of chromosome segregation (GO:0051985)3.21672262
88IMP metabolic process (GO:0046040)3.21033188
89regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.20920462
90negative regulation of mRNA processing (GO:0050686)3.20083724
91folic acid metabolic process (GO:0046655)3.19121807
92negative regulation of mitotic sister chromatid separation (GO:2000816)3.16472679
93negative regulation of mitotic sister chromatid segregation (GO:0033048)3.16472679
94negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.16472679
95negative regulation of sister chromatid segregation (GO:0033046)3.16472679
96positive regulation of cell cycle checkpoint (GO:1901978)3.16325260
97regulation of sister chromatid segregation (GO:0033045)3.16000462
98regulation of mitotic sister chromatid separation (GO:0010965)3.16000462
99regulation of mitotic sister chromatid segregation (GO:0033047)3.16000462
100cellular protein complex localization (GO:0034629)3.15328900
101nucleobase biosynthetic process (GO:0046112)3.15110587
102resolution of meiotic recombination intermediates (GO:0000712)3.14824332
103nuclear envelope organization (GO:0006998)3.14058543
104regulation of nucleobase-containing compound transport (GO:0032239)3.13418466
105somatic diversification of immune receptors via somatic mutation (GO:0002566)3.11237210
106somatic hypermutation of immunoglobulin genes (GO:0016446)3.11237210
107mitotic spindle checkpoint (GO:0071174)3.10760567
108negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.09588976
109mitotic spindle assembly checkpoint (GO:0007094)3.08815033
110mitotic DNA integrity checkpoint (GO:0044774)3.07837128
111negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.07080978
112protein K6-linked ubiquitination (GO:0085020)3.06792033
113negative regulation of DNA-dependent DNA replication (GO:2000104)3.05895264
114microtubule depolymerization (GO:0007019)3.04942362
115negative regulation of mRNA metabolic process (GO:1903312)3.04585504
116dosage compensation (GO:0007549)3.04431715
117positive regulation of DNA-dependent DNA replication (GO:2000105)3.03238811
118negative regulation of DNA repair (GO:0045738)3.00625416
119COPI coating of Golgi vesicle (GO:0048205)2.91288439
120Golgi transport vesicle coating (GO:0048200)2.91288439

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human6.67742836
2E2F4_17652178_ChIP-ChIP_JURKAT_Human5.00739901
3* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.90573202
4MYC_18555785_ChIP-Seq_MESCs_Mouse2.95344876
5EGR1_19374776_ChIP-ChIP_THP-1_Human2.81101812
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.60800652
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.59872604
8* E2F1_21310950_ChIP-Seq_MCF-7_Human2.56373575
9* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.42205437
10AR_21909140_ChIP-Seq_LNCAP_Human2.36237000
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.21101120
12* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.14305448
13NELFA_20434984_ChIP-Seq_ESCs_Mouse2.05668747
14MYC_22102868_ChIP-Seq_BL_Human2.04486863
15MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.03246933
16E2F7_22180533_ChIP-Seq_HELA_Human12.2583253
17KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.97565670
18CIITA_25753668_ChIP-Seq_RAJI_Human1.90985292
19EST1_17652178_ChIP-ChIP_JURKAT_Human1.85341012
20MYC_18358816_ChIP-ChIP_MESCs_Mouse1.84292442
21XRN2_22483619_ChIP-Seq_HELA_Human1.77197522
22VDR_23849224_ChIP-Seq_CD4+_Human1.76257947
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.73175716
24MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.72662962
25CREB1_15753290_ChIP-ChIP_HEK293T_Human1.72408145
26YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.70101414
27* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.69477208
28FOXP3_21729870_ChIP-Seq_TREG_Human1.68277233
29HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.65751788
30SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.59915849
31SALL1_21062744_ChIP-ChIP_HESCs_Human1.55036457
32ZNF263_19887448_ChIP-Seq_K562_Human1.53377817
33* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.53195752
34CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.51854311
35ETS1_20019798_ChIP-Seq_JURKAT_Human1.49090136
36ELK1_19687146_ChIP-ChIP_HELA_Human1.47249862
37HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.46821400
38* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.46621208
39HOXB4_20404135_ChIP-ChIP_EML_Mouse1.40817988
40GABP_17652178_ChIP-ChIP_JURKAT_Human1.39323196
41KDM5A_27292631_Chip-Seq_BREAST_Human1.39251635
42TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.38425267
43* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.35528633
44POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.34865857
45TTF2_22483619_ChIP-Seq_HELA_Human1.34715162
46SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.34004530
47NANOG_18555785_ChIP-Seq_MESCs_Mouse1.31146177
48CHD1_26751641_Chip-Seq_LNCaP_Human1.29544568
49VDR_21846776_ChIP-Seq_THP-1_Human1.29240547
50PADI4_21655091_ChIP-ChIP_MCF-7_Human1.29235977
51DCP1A_22483619_ChIP-Seq_HELA_Human1.28398235
52THAP11_20581084_ChIP-Seq_MESCs_Mouse1.28387733
53* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.27629519
54* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.26670379
55ELF1_17652178_ChIP-ChIP_JURKAT_Human1.24551138
56* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.22472779
57SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.21266555
58* GABP_19822575_ChIP-Seq_HepG2_Human1.19906952
59* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.19833257
60* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.19603878
61TP63_19390658_ChIP-ChIP_HaCaT_Human1.19386695
62ERG_20887958_ChIP-Seq_HPC-7_Mouse1.17964716
63NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.15175664
64ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.11987793
65CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.09287793
66CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.08651316
67SOX2_18555785_ChIP-Seq_MESCs_Mouse1.08556225
68TFEB_21752829_ChIP-Seq_HELA_Human1.05739942
69FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.04499977
70IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.04322848
71HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.03378516
72MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.02333950
73* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.00323441
74MYB_26560356_Chip-Seq_TH1_Human0.98998415
75HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.97502985
76* MYB_26560356_Chip-Seq_TH2_Human0.96633566
77KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.96418423
78UTX_26944678_Chip-Seq_JUKART_Human0.96185701
79KLF4_18555785_ChIP-Seq_MESCs_Mouse0.95323849
80* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.94314313
81SPI1_23547873_ChIP-Seq_NB4_Human0.94009640
82KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.93371807
83PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.92306280
84SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.91473362
85TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.91331016
86SCL_19346495_ChIP-Seq_HPC-7_Human0.90760478
87* MAF_26560356_Chip-Seq_TH1_Human0.86783820
88* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.86393034
89* SOX17_20123909_ChIP-Seq_XEN_Mouse0.85266923
90* PKCTHETA_26484144_Chip-Seq_BREAST_Human0.84999348
91* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.84853888
92STAT3_1855785_ChIP-Seq_MESCs_Mouse0.84431423
93* FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.84104275
94NCOR1_26117541_ChIP-Seq_K562_Human0.84017428
95* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.83844491
96TCF7_22412390_ChIP-Seq_EML_Mouse0.83667405
97NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.83543185
98NANOG_21062744_ChIP-ChIP_HESCs_Human0.83383539
99TBX5_21415370_ChIP-Seq_HL-1_Mouse0.82303333
100HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.82243747
101MYC_18940864_ChIP-ChIP_HL60_Human0.81599494
102KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.80749529
103ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.80682363
104POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.79949559
105KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.79767300
106ESR1_15608294_ChIP-ChIP_MCF-7_Human0.79679524
107NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.79635382
108TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.78938667
109* MYB_21317192_ChIP-Seq_ERMYB_Mouse0.77585484
110POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.77173383
111STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.77162698
112YY1_21170310_ChIP-Seq_MESCs_Mouse0.76766500
113RACK7_27058665_Chip-Seq_MCF-7_Human0.75169680
114SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.75116561
115* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.74851755
116CLOCK_20551151_ChIP-Seq_293T_Human0.74569249
117ATF3_27146783_Chip-Seq_COLON_Human0.74568285
118RUNX1_22412390_ChIP-Seq_EML_Mouse0.74453967
119FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.74306790
120PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.73767812
121TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.73449392
122ELK3_25401928_ChIP-Seq_HUVEC_Human0.72749314
123KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.71942845
124* TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.71604049
125* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.70349528

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability5.56309913
2MP0003111_abnormal_nucleus_morphology4.59986497
3MP0008057_abnormal_DNA_replication4.43271389
4MP0003693_abnormal_embryo_hatching4.29423834
5MP0003077_abnormal_cell_cycle4.03958390
6MP0004957_abnormal_blastocyst_morpholog3.61292081
7MP0008877_abnormal_DNA_methylation3.25132503
8MP0008058_abnormal_DNA_repair3.21655192
9MP0010307_abnormal_tumor_latency2.80870693
10MP0002396_abnormal_hematopoietic_system2.79447171
11MP0008007_abnormal_cellular_replicative2.62214569
12MP0003705_abnormal_hypodermis_morpholog2.35725596
13MP0001730_embryonic_growth_arrest2.28843064
14MP0004185_abnormal_adipocyte_glucose2.23392938
15MP0000350_abnormal_cell_proliferation2.20801644
16MP0008932_abnormal_embryonic_tissue2.16702954
17MP0004808_abnormal_hematopoietic_stem2.11045059
18MP0010352_gastrointestinal_tract_polyps2.10673278
19MP0003123_paternal_imprinting2.09648065
20MP0000569_abnormal_digit_pigmentation2.03462513
21MP0003121_genomic_imprinting1.90002970
22MP0005076_abnormal_cell_differentiation1.85798437
23MP0004233_abnormal_muscle_weight1.74047368
24MP0009697_abnormal_copulation1.72579521
25MP0001672_abnormal_embryogenesis/_devel1.71929973
26MP0005380_embryogenesis_phenotype1.71929973
27MP0000703_abnormal_thymus_morphology1.71715935
28MP0003763_abnormal_thymus_physiology1.70961987
29MP0001697_abnormal_embryo_size1.63777894
30MP0003786_premature_aging1.60596754
31MP0003890_abnormal_embryonic-extraembry1.59173295
32MP0002398_abnormal_bone_marrow1.57489827
33MP0003984_embryonic_growth_retardation1.57106463
34MP0010234_abnormal_vibrissa_follicle1.55331608
35MP0002088_abnormal_embryonic_growth/wei1.52344104
36MP0002019_abnormal_tumor_incidence1.49688700
37MP0003787_abnormal_imprinting1.48165888
38MP0002080_prenatal_lethality1.47241445
39MP0000490_abnormal_crypts_of1.46825594
40MP0004197_abnormal_fetal_growth/weight/1.45542687
41MP0002166_altered_tumor_susceptibility1.44241728
42MP0002084_abnormal_developmental_patter1.43690365
43MP0002086_abnormal_extraembryonic_tissu1.43484278
44MP0000313_abnormal_cell_death1.43467210
45MP0002085_abnormal_embryonic_tissue1.42726899
46MP0000537_abnormal_urethra_morphology1.40253013
47MP0002722_abnormal_immune_system1.38068006
48MP0005451_abnormal_body_composition1.33770062
49MP0004147_increased_porphyrin_level1.31928426
50MP0001661_extended_life_span1.31222949
51MP0000689_abnormal_spleen_morphology1.27654921
52MP0002210_abnormal_sex_determination1.26410699
53MP0009278_abnormal_bone_marrow1.26340304
54MP0002009_preneoplasia1.25948972
55MP0005397_hematopoietic_system_phenotyp1.25283974
56MP0001545_abnormal_hematopoietic_system1.25283974
57MP0002006_tumorigenesis1.19777452
58MP0001346_abnormal_lacrimal_gland1.17177059
59MP0001145_abnormal_male_reproductive1.08340103
60MP0001929_abnormal_gametogenesis1.07862681
61MP0002429_abnormal_blood_cell1.07604128
62MP0009703_decreased_birth_body1.03692623
63MP0005174_abnormal_tail_pigmentation1.02574889
64MP0003567_abnormal_fetal_cardiomyocyte1.01863785
65MP0003566_abnormal_cell_adhesion1.01686214
66MP0000716_abnormal_immune_system1.01527779
67MP0005501_abnormal_skin_physiology0.98055910
68MP0001800_abnormal_humoral_immune0.97929765
69MP0009672_abnormal_birth_weight0.97621668
70MP0002095_abnormal_skin_pigmentation0.96974626
71MP0002697_abnormal_eye_size0.93383313
72MP0005621_abnormal_cell_physiology0.93194865
73MP0000653_abnormal_sex_gland0.92930709
74MP0000465_gastrointestinal_hemorrhage0.92322292
75MP0002877_abnormal_melanocyte_morpholog0.91396882
76MP0001293_anophthalmia0.90175265
77MP0005384_cellular_phenotype0.88915391
78MP0003656_abnormal_erythrocyte_physiolo0.88646739
79MP0000358_abnormal_cell_content/0.88301985
80MP0002420_abnormal_adaptive_immunity0.86777475
81MP0005666_abnormal_adipose_tissue0.86749959
82MP0003943_abnormal_hepatobiliary_system0.86103382
83MP0009333_abnormal_splenocyte_physiolog0.85749276
84MP0005623_abnormal_meninges_morphology0.84187994
85MP0003221_abnormal_cardiomyocyte_apopto0.83800587
86MP0001819_abnormal_immune_cell0.83735478
87MP0001849_ear_inflammation0.83287668
88MP0000015_abnormal_ear_pigmentation0.80730926
89MP0000428_abnormal_craniofacial_morphol0.80139268
90MP0002796_impaired_skin_barrier0.79488747
91MP0001915_intracranial_hemorrhage0.77473264
92MP0006054_spinal_hemorrhage0.76211444
93MP0005671_abnormal_response_to0.75516112
94MP0002452_abnormal_antigen_presenting0.75302445
95MP0000678_abnormal_parathyroid_gland0.74761152
96MP0002075_abnormal_coat/hair_pigmentati0.74485149
97MP0006035_abnormal_mitochondrial_morpho0.73817442
98MP0002111_abnormal_tail_morphology0.72970542
99MP0002970_abnormal_white_adipose0.72703153
100MP0000627_abnormal_mammary_gland0.72548035
101MP0005220_abnormal_exocrine_pancreas0.72138601
102MP0005464_abnormal_platelet_physiology0.71667068
103MP0008995_early_reproductive_senescence0.71593419
104MP0000733_abnormal_muscle_development0.70663479
105MP0010678_abnormal_skin_adnexa0.69915816
106MP0001119_abnormal_female_reproductive0.69803824
107MP0003718_maternal_effect0.69061979
108MP0001873_stomach_inflammation0.68873409
109MP0001727_abnormal_embryo_implantation0.68818541
110MP0001881_abnormal_mammary_gland0.67786014
111MP0001286_abnormal_eye_development0.67330163
112MP0003115_abnormal_respiratory_system0.66934220
113MP0008961_abnormal_basal_metabolism0.66062532
114MP0000371_diluted_coat_color0.66060647
115MP0002060_abnormal_skin_morphology0.65652638
116MP0003935_abnormal_craniofacial_develop0.64937813
117MP0002723_abnormal_immune_serum0.64785614
118MP0001216_abnormal_epidermal_layer0.64436414
119MP0003300_gastrointestinal_ulcer0.63758618
120MP0000432_abnormal_head_morphology0.63737159
121MP0001835_abnormal_antigen_presentation0.62748985
122MP0010155_abnormal_intestine_physiology0.62263453
123MP0002092_abnormal_eye_morphology0.61320631
124MP0004264_abnormal_extraembryonic_tissu0.61152168
125MP0002405_respiratory_system_inflammati0.61142797
126MP0010030_abnormal_orbit_morphology0.60748140
127MP0003315_abnormal_perineum_morphology0.60205680
128MP0010630_abnormal_cardiac_muscle0.60096080
129MP0003861_abnormal_nervous_system0.59720699
130MP0000685_abnormal_immune_system0.59682194
131MP0003698_abnormal_male_reproductive0.59627670
132MP0006072_abnormal_retinal_apoptosis0.59388731
133MP0000003_abnormal_adipose_tissue0.59383501
134MP0003937_abnormal_limbs/digits/tail_de0.58694772
135MP0002925_abnormal_cardiovascular_devel0.57551563
136MP0002114_abnormal_axial_skeleton0.56611479
137MP0002234_abnormal_pharynx_morphology0.56021574
138MP0001348_abnormal_lacrimal_gland0.55775215
139MP0003942_abnormal_urinary_system0.55748604
140MP0003385_abnormal_body_wall0.55600827
141MP0008770_decreased_survivor_rate0.55112692
142MP0000383_abnormal_hair_follicle0.54632389
143MP0005391_vision/eye_phenotype0.53044333
144MP0003699_abnormal_female_reproductive0.52645970

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)5.09200507
2Chromosomal breakage induced by crosslinking agents (HP:0003221)4.83534922
3Volvulus (HP:0002580)4.33908619
4Abnormality of chromosome stability (HP:0003220)4.31509747
5Birth length less than 3rd percentile (HP:0003561)4.12733525
6Ependymoma (HP:0002888)3.43714033
7Abnormality of the preputium (HP:0100587)3.36201628
8Abnormality of the fingertips (HP:0001211)3.32295191
9Meckel diverticulum (HP:0002245)3.32073974
10Aplasia/Hypoplasia of the uvula (HP:0010293)3.31392484
11Ectopic kidney (HP:0000086)3.29546907
12Abnormality of the ileum (HP:0001549)3.24155198
13Medulloblastoma (HP:0002885)3.23800148
14Increased nuchal translucency (HP:0010880)3.19348006
15Reticulocytopenia (HP:0001896)3.18067192
16Myelodysplasia (HP:0002863)3.05797206
17Panhypogammaglobulinemia (HP:0003139)2.92118694
18Colon cancer (HP:0003003)2.90972999
19Small intestinal stenosis (HP:0012848)2.88735171
20Duodenal stenosis (HP:0100867)2.88735171
21IgM deficiency (HP:0002850)2.82744242
22Abnormality of the carotid arteries (HP:0005344)2.79941146
23Microvesicular hepatic steatosis (HP:0001414)2.78401914
24Prominent nose (HP:0000448)2.74362403
25Cafe-au-lait spot (HP:0000957)2.68964917
26Basal cell carcinoma (HP:0002671)2.67238709
27Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.63951654
28Short 4th metacarpal (HP:0010044)2.63951654
29Duplicated collecting system (HP:0000081)2.60945128
30Agnosia (HP:0010524)2.60153431
31Recurrent viral infections (HP:0004429)2.58148753
32High pitched voice (HP:0001620)2.57240463
33Bone marrow hypocellularity (HP:0005528)2.56329481
34Impulsivity (HP:0100710)2.56255468
35Septate vagina (HP:0001153)2.56004093
36Proximal placement of thumb (HP:0009623)2.55805930
37Astrocytoma (HP:0009592)2.54610928
38Abnormality of the astrocytes (HP:0100707)2.54610928
39Sloping forehead (HP:0000340)2.51553033
40Abnormality of the labia minora (HP:0012880)2.50854989
41Overlapping toe (HP:0001845)2.48366992
42Deviation of the thumb (HP:0009603)2.47177558
4311 pairs of ribs (HP:0000878)2.45414552
44Rhabdomyosarcoma (HP:0002859)2.41655652
45Clubbing of toes (HP:0100760)2.40785271
46Progressive muscle weakness (HP:0003323)2.40343980
47Chronic otitis media (HP:0000389)2.39977737
48Abnormality of the renal collecting system (HP:0004742)2.39135682
49Breast hypoplasia (HP:0003187)2.39075477
50Abnormality of the duodenum (HP:0002246)2.38648404
51Patellar aplasia (HP:0006443)2.36277211
52Ankyloglossia (HP:0010296)2.36207624
53Selective tooth agenesis (HP:0001592)2.35984960
54Cortical dysplasia (HP:0002539)2.30074282
55Neoplasm of the oral cavity (HP:0100649)2.27035760
56Glioma (HP:0009733)2.26054961
57Absent thumb (HP:0009777)2.25659089
58Insomnia (HP:0100785)2.23982831
59T lymphocytopenia (HP:0005403)2.23409000
60Biliary tract neoplasm (HP:0100574)2.21856034
61Long eyelashes (HP:0000527)2.19986382
62Multiple enchondromatosis (HP:0005701)2.19786317
63Squamous cell carcinoma (HP:0002860)2.19764550
64Abnormality of B cell number (HP:0010975)2.18756572
65B lymphocytopenia (HP:0010976)2.18756572
66High anterior hairline (HP:0009890)2.18477837
67Lymphoma (HP:0002665)2.17455084
68Urethral obstruction (HP:0000796)2.17388911
69Nephroblastoma (Wilms tumor) (HP:0002667)2.16574303
70Sparse lateral eyebrow (HP:0005338)2.16301617
71Abnormality of chromosome segregation (HP:0002916)2.16069554
72Truncal obesity (HP:0001956)2.15659899
73Abnormality of DNA repair (HP:0003254)2.14233483
74Missing ribs (HP:0000921)2.13585751
75Abnormal foot bone ossification (HP:0010675)2.13182927
76Abnormality of the phalanges of the hallux (HP:0010057)2.12759636
77Aplasia/Hypoplasia of the patella (HP:0006498)2.12236073
78Abnormality of the prostate (HP:0008775)2.09868071
79Termporal pattern (HP:0011008)2.08230919
80Insidious onset (HP:0003587)2.08230919
81Trigonocephaly (HP:0000243)2.08175704
82Abnormality of the distal phalanx of the thumb (HP:0009617)2.06561556
83Absent radius (HP:0003974)2.06342531
84Dysmetric saccades (HP:0000641)2.06034657
85Aplasia/Hypoplasia of the sacrum (HP:0008517)2.05863604
86Amaurosis fugax (HP:0100576)2.03374481
87Combined immunodeficiency (HP:0005387)2.01653445
88Progressive external ophthalmoplegia (HP:0000590)2.01201924
89Abnormality of oral frenula (HP:0000190)2.00968841
90Oral leukoplakia (HP:0002745)1.99735274
91Deep philtrum (HP:0002002)1.99344071
92Broad face (HP:0000283)1.99123411
93Broad distal phalanx of finger (HP:0009836)1.98331980
94Abnormal lung lobation (HP:0002101)1.98277843
95Orthostatic hypotension (HP:0001278)1.96684580
96Duplication of thumb phalanx (HP:0009942)1.95704126
97Embryonal renal neoplasm (HP:0011794)1.95058561
98Abnormality of T cell number (HP:0011839)1.94986448
99Sandal gap (HP:0001852)1.94271922
100Neoplasm of the pancreas (HP:0002894)1.93546832
101Abnormality of the calcaneus (HP:0008364)1.93197807
102Neoplasm of striated muscle (HP:0009728)1.92598576
103Choanal atresia (HP:0000453)1.92008005
104Severe combined immunodeficiency (HP:0004430)1.91715727
105Abnormality of cochlea (HP:0000375)1.91240608
106Cellular immunodeficiency (HP:0005374)1.91107540
107Short thumb (HP:0009778)1.90215373
108Abnormal gallbladder physiology (HP:0012438)1.89344525
109Cholecystitis (HP:0001082)1.89344525
110Tracheoesophageal fistula (HP:0002575)1.89328625
111Acute myeloid leukemia (HP:0004808)1.89265265
112Neoplasm of the colon (HP:0100273)1.88866086
113Aplasia involving forearm bones (HP:0009822)1.88652843
114Absent forearm bone (HP:0003953)1.88652843
115Thyroiditis (HP:0100646)1.88349260
116Abnormality of the heme biosynthetic pathway (HP:0010472)1.87817055
117Poikiloderma (HP:0001029)1.87720015
118Arteriovenous malformation (HP:0100026)1.86402694
119Heterotopia (HP:0002282)1.86375837
120Premature graying of hair (HP:0002216)1.86193120
121Gastrointestinal carcinoma (HP:0002672)1.85775087
122Malignant gastrointestinal tract tumors (HP:0006749)1.85775087
123Abnormality of the fetal cardiovascular system (HP:0010948)1.85506201
124Abnormal umbilical cord blood vessels (HP:0011403)1.85506201
125Single umbilical artery (HP:0001195)1.85506201
126Abnormal number of incisors (HP:0011064)1.84857629
127Abnormality of the umbilical cord (HP:0010881)1.84314797
128Hypoplasia of the capital femoral epiphysis (HP:0003090)1.83951062
129Abnormality of glycolysis (HP:0004366)1.82484384
130Abnormality of the distal phalanges of the toes (HP:0010182)1.81969107
131Embryonal neoplasm (HP:0002898)1.81835176
132Hyperacusis (HP:0010780)1.81720605
133Leukopenia (HP:0001882)1.81464577
134Facial hemangioma (HP:0000329)1.81353516
135Asymmetry of the thorax (HP:0001555)1.80575407
136Acute lymphatic leukemia (HP:0006721)1.80324954
137Aplasia/Hypoplasia of the sternum (HP:0006714)1.79371171
138Atresia of the external auditory canal (HP:0000413)1.77591938
139Long clavicles (HP:0000890)1.76432828
140Obsessive-compulsive behavior (HP:0000722)1.76364713
141Aplastic anemia (HP:0001915)1.76158814
142Patellar dislocation (HP:0002999)1.75646146
143Abnormality of reticulocytes (HP:0004312)1.74500822
144Flat acetabular roof (HP:0003180)1.73096398
145Homocystinuria (HP:0002156)1.72248994
146Abnormality of homocysteine metabolism (HP:0010919)1.72248994
147Entropion (HP:0000621)1.69310684
148Relative macrocephaly (HP:0004482)1.64758576
149Trismus (HP:0000211)1.63659405
150Deep palmar crease (HP:0006191)1.61672651
151Leiomyosarcoma (HP:0100243)1.60883670

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC75.55984524
2NEK23.56538643
3CDK123.41821293
4WEE13.40390741
5SMG13.28693995
6TRIB32.87665079
7BUB12.84131238
8TTK2.47244137
9NEK12.29678381
10EEF2K2.28327378
11ICK2.22032055
12ATR2.20449867
13BRSK22.18993724
14BRD42.07001423
15EIF2AK12.03526246
16CCNB11.99102474
17SRPK11.96999988
18PASK1.95070400
19PLK11.87799892
20AURKB1.84412190
21STK41.81552223
22MAP4K11.75118826
23RPS6KB21.71594683
24TLK11.67906317
25PLK31.66936820
26TSSK61.66860178
27CDK41.64844953
28BRSK11.63649508
29STK101.60214453
30IRAK31.56044190
31CDK71.55489164
32ACVR1B1.55319331
33CHEK11.54630544
34CHEK21.53250469
35VRK11.49669375
36NME21.41227104
37CDK61.40813361
38PLK41.40302403
39TAF11.36882411
40CLK11.36207179
41MAP3K101.35320195
42MKNK11.33461699
43ATM1.29536343
44MAP3K81.28486106
45ZAK1.23711389
46MST1R1.23358829
47VRK21.20330102
48MELK1.18723327
49TEC1.17532543
50PKN21.14459909
51SCYL21.13404503
52ITK1.10346177
53CDK81.09850125
54PRPF4B1.08170081
55MKNK21.05304223
56CDK21.05078939
57PIM10.98745059
58BTK0.97372879
59EIF2AK30.94685018
60CDK10.93666319
61FLT30.93292682
62BRAF0.87008219
63MAP3K140.84257160
64CDK90.81412963
65DYRK30.80657043
66RPS6KA40.80239291
67SIK10.78962847
68TYK20.78834004
69AURKA0.77141478
70PNCK0.73923507
71ALK0.71143226
72GRK60.67951612
73EPHA20.67642471
74MTOR0.64766413
75MAPK110.64671643
76LATS10.63410507
77PRKDC0.63007788
78STK30.61756301
79CAMK1D0.61336501
80TGFBR10.58857257
81RPS6KA50.58110868
82PAK40.57720558
83TXK0.56638340
84CSF1R0.56160690
85JAK30.55105827
86CSNK1D0.53514222
87KSR20.52918671
88MAPK140.49474636
89TTN0.49203513
90PAK20.49186919
91CSNK2A20.48421871
92TRPM70.47721964
93RPS6KB10.46595399
94TESK20.45715942
95LCK0.45478039
96PDGFRA0.44866579
97RAF10.44628970
98EIF2AK20.41434062
99FGFR40.41095198
100MAP3K130.40440054
101SYK0.39902956
102DYRK1B0.39588203
103MET0.38803896
104CAMK1G0.38431505
105AKT10.37612558
106CSNK1E0.36701171
107GSK3B0.36254980
108KIT0.35579220
109CDK30.35482680
110LRRK20.35408089
111LATS20.35242153
112RPS6KC10.34912430
113RPS6KL10.34912430
114MAPK10.34890192
115CSNK2A10.33940026
116ZAP700.32917815
117ERBB40.32709797
118CDK150.32378137
119AKT20.32203231
120CDK11A0.32057707
121FGFR10.31636482
122UHMK10.31620351
123CHUK0.31231674
124PRKCI0.31229191
125AKT30.30212277
126CDK180.30109407
127RPS6KA60.29660845
128IRAK20.29296896
129PAK10.27566150
130TAOK10.26938933
131PTK60.26275381
132IRAK40.26259316
133PBK0.25950592
134YES10.25600126
135PTK20.23016965

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.41631748
2Mismatch repair_Homo sapiens_hsa034304.74639352
3Base excision repair_Homo sapiens_hsa034103.63111778
4Homologous recombination_Homo sapiens_hsa034403.34852967
5Cell cycle_Homo sapiens_hsa041103.32805166
6Non-homologous end-joining_Homo sapiens_hsa034502.97380228
7Fanconi anemia pathway_Homo sapiens_hsa034602.94887154
8Spliceosome_Homo sapiens_hsa030402.92249016
9Nucleotide excision repair_Homo sapiens_hsa034202.73589799
10RNA transport_Homo sapiens_hsa030132.73140200
11Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.70385951
12One carbon pool by folate_Homo sapiens_hsa006702.67220647
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.15546715
14mRNA surveillance pathway_Homo sapiens_hsa030152.15208056
15Systemic lupus erythematosus_Homo sapiens_hsa053222.13975811
16RNA degradation_Homo sapiens_hsa030181.95528799
17Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.79151618
18RNA polymerase_Homo sapiens_hsa030201.68548707
19Pyrimidine metabolism_Homo sapiens_hsa002401.65911126
20p53 signaling pathway_Homo sapiens_hsa041151.65079028
21Primary immunodeficiency_Homo sapiens_hsa053401.63125322
22Basal transcription factors_Homo sapiens_hsa030221.49774519
23Viral carcinogenesis_Homo sapiens_hsa052031.47671755
24Ribosome_Homo sapiens_hsa030101.36512607
252-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.32704488
26Herpes simplex infection_Homo sapiens_hsa051681.24196859
27Oocyte meiosis_Homo sapiens_hsa041141.23539893
28Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.22325163
29Carbon metabolism_Homo sapiens_hsa012001.14109000
30Antigen processing and presentation_Homo sapiens_hsa046121.11617196
31Epstein-Barr virus infection_Homo sapiens_hsa051691.11563745
32Alcoholism_Homo sapiens_hsa050341.09805902
33Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.08433206
34HTLV-I infection_Homo sapiens_hsa051661.04583944
35Lysine degradation_Homo sapiens_hsa003101.04263541
36MicroRNAs in cancer_Homo sapiens_hsa052061.01128061
37Transcriptional misregulation in cancer_Homo sapiens_hsa052020.96476252
38Proteasome_Homo sapiens_hsa030500.94594604
39Small cell lung cancer_Homo sapiens_hsa052220.93799676
40NF-kappa B signaling pathway_Homo sapiens_hsa040640.92246724
41Chronic myeloid leukemia_Homo sapiens_hsa052200.90314621
42Purine metabolism_Homo sapiens_hsa002300.89363373
43Pyruvate metabolism_Homo sapiens_hsa006200.87850397
44Fatty acid biosynthesis_Homo sapiens_hsa000610.85272272
45B cell receptor signaling pathway_Homo sapiens_hsa046620.82273192
46Measles_Homo sapiens_hsa051620.80627692
47Hepatitis B_Homo sapiens_hsa051610.79597665
48Colorectal cancer_Homo sapiens_hsa052100.75540499
49Fructose and mannose metabolism_Homo sapiens_hsa000510.74741055
50T cell receptor signaling pathway_Homo sapiens_hsa046600.74005009
51Apoptosis_Homo sapiens_hsa042100.69024158
52Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.66826448
53Pancreatic cancer_Homo sapiens_hsa052120.66716277
54Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.66600024
55Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.65320378
56Viral myocarditis_Homo sapiens_hsa054160.61534185
57Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.60563607
58Non-small cell lung cancer_Homo sapiens_hsa052230.59832877
59Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.58653919
60Hematopoietic cell lineage_Homo sapiens_hsa046400.58526440
61Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.57973217
62Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.56872349
63Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.54182300
64Prostate cancer_Homo sapiens_hsa052150.52833812
65Acute myeloid leukemia_Homo sapiens_hsa052210.52080508
66Longevity regulating pathway - mammal_Homo sapiens_hsa042110.51347029
67Selenocompound metabolism_Homo sapiens_hsa004500.50142358
68Renal cell carcinoma_Homo sapiens_hsa052110.49631894
69mTOR signaling pathway_Homo sapiens_hsa041500.49631774
70AMPK signaling pathway_Homo sapiens_hsa041520.48605028
71Influenza A_Homo sapiens_hsa051640.47107010
72NOD-like receptor signaling pathway_Homo sapiens_hsa046210.46462602
73FoxO signaling pathway_Homo sapiens_hsa040680.46397374
74Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.46027489
75Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.45487469
76Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.45235526
77Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.45067426
78Notch signaling pathway_Homo sapiens_hsa043300.44580692
79Thyroid hormone signaling pathway_Homo sapiens_hsa049190.44365218
80Steroid biosynthesis_Homo sapiens_hsa001000.43718439
81Thyroid cancer_Homo sapiens_hsa052160.43552935
82Folate biosynthesis_Homo sapiens_hsa007900.42717429
83Insulin signaling pathway_Homo sapiens_hsa049100.42657860
84Shigellosis_Homo sapiens_hsa051310.41890446
85Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.41763807
86Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.41485494
87Sulfur relay system_Homo sapiens_hsa041220.40694303
88Melanoma_Homo sapiens_hsa052180.40314887
89Hippo signaling pathway_Homo sapiens_hsa043900.39812100
90ErbB signaling pathway_Homo sapiens_hsa040120.38807718
91Fatty acid metabolism_Homo sapiens_hsa012120.38204874
92Galactose metabolism_Homo sapiens_hsa000520.37819371
93Platelet activation_Homo sapiens_hsa046110.36815139
94Pathways in cancer_Homo sapiens_hsa052000.35704215
95Intestinal immune network for IgA production_Homo sapiens_hsa046720.35098519
96Biosynthesis of amino acids_Homo sapiens_hsa012300.33655944
97Adherens junction_Homo sapiens_hsa045200.33251113
98Pentose phosphate pathway_Homo sapiens_hsa000300.33084904
99N-Glycan biosynthesis_Homo sapiens_hsa005100.32334081
100Leukocyte transendothelial migration_Homo sapiens_hsa046700.31351627
101Central carbon metabolism in cancer_Homo sapiens_hsa052300.30912362
102Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.30896810
103Phototransduction_Homo sapiens_hsa047440.30623116
104Osteoclast differentiation_Homo sapiens_hsa043800.30550013
105TGF-beta signaling pathway_Homo sapiens_hsa043500.29878714
106Legionellosis_Homo sapiens_hsa051340.29877917
107Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.29715525
108Drug metabolism - other enzymes_Homo sapiens_hsa009830.28165045
109Wnt signaling pathway_Homo sapiens_hsa043100.27992446
110Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.27875677
111HIF-1 signaling pathway_Homo sapiens_hsa040660.27545018
112Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.27534458
113Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.27192054
114Jak-STAT signaling pathway_Homo sapiens_hsa046300.26925962
115Vitamin B6 metabolism_Homo sapiens_hsa007500.26449948
116Inositol phosphate metabolism_Homo sapiens_hsa005620.25702868
117Glucagon signaling pathway_Homo sapiens_hsa049220.23800489
118RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.23709185
119Basal cell carcinoma_Homo sapiens_hsa052170.22782059
120Toxoplasmosis_Homo sapiens_hsa051450.21889093
121Cysteine and methionine metabolism_Homo sapiens_hsa002700.21673693
122Arginine biosynthesis_Homo sapiens_hsa002200.20356402
123Cyanoamino acid metabolism_Homo sapiens_hsa004600.19613809
124Endometrial cancer_Homo sapiens_hsa052130.19402876
125Chemokine signaling pathway_Homo sapiens_hsa040620.16610564
126Leishmaniasis_Homo sapiens_hsa051400.16163797
127Proteoglycans in cancer_Homo sapiens_hsa052050.12379229
128Phosphatidylinositol signaling system_Homo sapiens_hsa040700.11998369
129Glioma_Homo sapiens_hsa052140.11628119
130Bladder cancer_Homo sapiens_hsa052190.11611760
131Neurotrophin signaling pathway_Homo sapiens_hsa047220.10953589

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