NANP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)4.96675687
2protein K6-linked ubiquitination (GO:0085020)4.63177090
3mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.59611984
4energy coupled proton transport, down electrochemical gradient (GO:0015985)4.29823117
5ATP synthesis coupled proton transport (GO:0015986)4.29823117
6establishment of integrated proviral latency (GO:0075713)4.27952312
7DNA deamination (GO:0045006)4.17447429
8telomere maintenance via semi-conservative replication (GO:0032201)4.17317563
9proteasome assembly (GO:0043248)4.10623194
10dopamine transport (GO:0015872)4.10606333
11DNA strand elongation involved in DNA replication (GO:0006271)4.06892784
12mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.03967966
13mitochondrial respiratory chain complex I assembly (GO:0032981)4.03967966
14NADH dehydrogenase complex assembly (GO:0010257)4.03967966
15protoporphyrinogen IX biosynthetic process (GO:0006782)3.93326689
16protein complex biogenesis (GO:0070271)3.91451501
17deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.89173345
18DNA replication initiation (GO:0006270)3.88751818
19DNA strand elongation (GO:0022616)3.84300394
20protoporphyrinogen IX metabolic process (GO:0046501)3.79259564
21chaperone-mediated protein transport (GO:0072321)3.78654953
22DNA double-strand break processing (GO:0000729)3.75180092
23DNA replication checkpoint (GO:0000076)3.68685088
24nuclear pore organization (GO:0006999)3.68335294
25oxidative phosphorylation (GO:0006119)3.68142557
26mitochondrial respiratory chain complex assembly (GO:0033108)3.65645749
27mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.64494560
28L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.62410746
29ribosomal small subunit biogenesis (GO:0042274)3.61721870
30ribosome assembly (GO:0042255)3.61470420
31viral transcription (GO:0019083)3.59932649
32telomere maintenance via recombination (GO:0000722)3.57075420
33translational termination (GO:0006415)3.54269020
34positive regulation of protein homodimerization activity (GO:0090073)3.54006349
35regulation of DNA endoreduplication (GO:0032875)3.50692183
36cullin deneddylation (GO:0010388)3.49119008
37deoxyribose phosphate biosynthetic process (GO:0046385)3.49115553
382-deoxyribonucleotide biosynthetic process (GO:0009265)3.49115553
39GTP biosynthetic process (GO:0006183)3.49048935
40regulation of mitochondrial translation (GO:0070129)3.47621405
41negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.45923159
42establishment of viral latency (GO:0019043)3.44911792
43pseudouridine synthesis (GO:0001522)3.44155304
44somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.44097471
45somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.44097471
46isotype switching (GO:0045190)3.44097471
47protein deneddylation (GO:0000338)3.42481214
48CENP-A containing nucleosome assembly (GO:0034080)3.42289210
49chromatin remodeling at centromere (GO:0031055)3.42233720
50protein-cofactor linkage (GO:0018065)3.40190062
51respiratory electron transport chain (GO:0022904)3.39642687
52nuclear pore complex assembly (GO:0051292)3.38594014
53respiratory chain complex IV assembly (GO:0008535)3.38436014
54negative regulation of DNA-dependent DNA replication (GO:2000104)3.36234920
55maturation of SSU-rRNA (GO:0030490)3.36141131
56mitotic metaphase plate congression (GO:0007080)3.35299101
57synapsis (GO:0007129)3.34477734
58water-soluble vitamin biosynthetic process (GO:0042364)3.32934711
59deoxyribonucleotide biosynthetic process (GO:0009263)3.32885904
60electron transport chain (GO:0022900)3.32620219
61nucleobase biosynthetic process (GO:0046112)3.31914719
62regulation of cellular amino acid metabolic process (GO:0006521)3.30239921
63establishment of protein localization to mitochondrial membrane (GO:0090151)3.28789535
64DNA unwinding involved in DNA replication (GO:0006268)3.27003751
65purine nucleobase biosynthetic process (GO:0009113)3.26220661
66DNA strand renaturation (GO:0000733)3.25882390
67ribosomal large subunit biogenesis (GO:0042273)3.25370906
68maturation of 5.8S rRNA (GO:0000460)3.25096061
69mitotic recombination (GO:0006312)3.24565975
70rRNA modification (GO:0000154)3.23821182
71translational elongation (GO:0006414)3.23505663
72guanosine-containing compound biosynthetic process (GO:1901070)3.22335260
73cotranslational protein targeting to membrane (GO:0006613)3.22234979
74inner mitochondrial membrane organization (GO:0007007)3.21539165
75DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.20478941
76SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.19983688
77heme biosynthetic process (GO:0006783)3.18991222
78nucleotide-excision repair, DNA gap filling (GO:0006297)3.18655391
79pteridine-containing compound biosynthetic process (GO:0042559)3.17887899
80metaphase plate congression (GO:0051310)3.17407675
81double-strand break repair via nonhomologous end joining (GO:0006303)3.16790920
82non-recombinational repair (GO:0000726)3.16790920
83replication fork processing (GO:0031297)3.16748551
84telomere maintenance via telomere lengthening (GO:0010833)3.15377159
85signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.14918273
86intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.14918273
87IMP biosynthetic process (GO:0006188)3.14185235
88attachment of spindle microtubules to kinetochore (GO:0008608)3.14143158
89signal peptide processing (GO:0006465)3.14072476
90transcription elongation from RNA polymerase III promoter (GO:0006385)3.13578231
91termination of RNA polymerase III transcription (GO:0006386)3.13578231
92oxaloacetate metabolic process (GO:0006107)3.13169585
93cellular component biogenesis (GO:0044085)3.12911470
94regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.12765875
95dolichol-linked oligosaccharide biosynthetic process (GO:0006488)3.12532000
96UTP biosynthetic process (GO:0006228)3.12420290
97protein targeting to ER (GO:0045047)3.12341143
98negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.12226320
99negative regulation of ligase activity (GO:0051352)3.12226320
100positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.11983277
101anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.10397895
102RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.10279023
103tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.10279023
104signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.09340989
105signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.09340989
106signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.09340989
107NADH metabolic process (GO:0006734)3.08370403
108spliceosomal snRNP assembly (GO:0000387)3.07955906
109protein targeting to mitochondrion (GO:0006626)3.05380992
110histone exchange (GO:0043486)3.05363644
111metallo-sulfur cluster assembly (GO:0031163)3.04587505
112iron-sulfur cluster assembly (GO:0016226)3.04587505
113ribonucleoprotein complex biogenesis (GO:0022613)3.03681262
1147-methylguanosine mRNA capping (GO:0006370)3.02882677
115DNA catabolic process, exonucleolytic (GO:0000738)3.02467011
116folic acid-containing compound biosynthetic process (GO:0009396)3.02141999
1177-methylguanosine RNA capping (GO:0009452)3.00924769
118RNA capping (GO:0036260)3.00924769
119regulation of centriole replication (GO:0046599)3.00816250
120exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.00662878
121protein localization to endoplasmic reticulum (GO:0070972)3.00622424
122meiotic chromosome segregation (GO:0045132)3.00034160
123establishment of protein localization to mitochondrion (GO:0072655)2.99091273
124pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.99002339
125mitotic sister chromatid segregation (GO:0000070)2.98876284
126translation (GO:0006412)2.98468816
127cellular protein complex disassembly (GO:0043624)2.97985161
128signal transduction involved in DNA integrity checkpoint (GO:0072401)2.97309331
129histone mRNA metabolic process (GO:0008334)2.95414369
130mitotic sister chromatid cohesion (GO:0007064)2.94405742
131nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.91364876
132lactate metabolic process (GO:0006089)2.88582633
133somatic recombination of immunoglobulin gene segments (GO:0016447)2.87308558
134UDP-N-acetylglucosamine metabolic process (GO:0006047)2.86605359
135signal transduction involved in DNA damage checkpoint (GO:0072422)2.85779109
136G1/S transition of mitotic cell cycle (GO:0000082)2.84291892
137cell cycle G1/S phase transition (GO:0044843)2.84291892
138kinetochore organization (GO:0051383)2.83490266
139positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.83037670
140spindle checkpoint (GO:0031577)2.82936885
141mitochondrial RNA metabolic process (GO:0000959)2.82741234
142signal transduction involved in cell cycle checkpoint (GO:0072395)2.82256492
143DNA replication-dependent nucleosome organization (GO:0034723)2.79064183
144DNA replication-dependent nucleosome assembly (GO:0006335)2.79064183
145regulation of nuclear cell cycle DNA replication (GO:0033262)2.78899200
146regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.78263221
147regulation of mitotic spindle checkpoint (GO:1903504)2.78263221
148protein localization to kinetochore (GO:0034501)2.78173579
149somatic hypermutation of immunoglobulin genes (GO:0016446)2.78046506
150somatic diversification of immune receptors via somatic mutation (GO:0002566)2.78046506
151mitotic nuclear envelope disassembly (GO:0007077)2.77182639
152RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.76386965
153sister chromatid segregation (GO:0000819)2.76070445
154double-strand break repair via homologous recombination (GO:0000724)2.74395233
155recombinational repair (GO:0000725)2.74027474
156IMP metabolic process (GO:0046040)2.72655307
157positive regulation of ligase activity (GO:0051351)2.71504270
158somatic diversification of immunoglobulins (GO:0016445)2.69983781
159mitotic spindle checkpoint (GO:0071174)2.68658769

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.46284001
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.66903986
3EST1_17652178_ChIP-ChIP_JURKAT_Human4.01321767
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.98014123
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.95852456
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.77238320
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.62693212
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.56513426
9HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.34597486
10E2F4_17652178_ChIP-ChIP_JURKAT_Human3.34414147
11ETS1_20019798_ChIP-Seq_JURKAT_Human3.20761293
12* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.98455283
13SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.92993744
14ELF1_17652178_ChIP-ChIP_JURKAT_Human2.92541436
15* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.88721836
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.79122503
17THAP11_20581084_ChIP-Seq_MESCs_Mouse2.75851552
18* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.61217977
19MYC_19079543_ChIP-ChIP_MESCs_Mouse2.56339932
20MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.55220861
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.48491774
22SALL1_21062744_ChIP-ChIP_HESCs_Human2.46492354
23VDR_23849224_ChIP-Seq_CD4+_Human2.42400884
24SRF_21415370_ChIP-Seq_HL-1_Mouse2.40173812
25PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.30694532
26FOXP3_21729870_ChIP-Seq_TREG_Human2.30477666
27E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.27197556
28ZNF274_21170338_ChIP-Seq_K562_Hela2.20181253
29E2F1_18555785_ChIP-Seq_MESCs_Mouse2.17552931
30RBPJ_22232070_ChIP-Seq_NCS_Mouse2.13390612
31DCP1A_22483619_ChIP-Seq_HELA_Human2.10459132
32FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.07403266
33ELK1_19687146_ChIP-ChIP_HELA_Human2.06128411
34* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.00314961
35XRN2_22483619_ChIP-Seq_HELA_Human2.00239136
36* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.94242456
37ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.94010966
38SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.90727664
39TTF2_22483619_ChIP-Seq_HELA_Human1.85887490
40YY1_21170310_ChIP-Seq_MESCs_Mouse1.85616175
41YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.84733554
42GABP_19822575_ChIP-Seq_HepG2_Human1.83842681
43* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.82766642
44* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.79118908
45CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.74871503
46MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.70063346
47POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.66969952
48FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.63024670
49FLI1_27457419_Chip-Seq_LIVER_Mouse1.62397083
50MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.62257962
51PADI4_21655091_ChIP-ChIP_MCF-7_Human1.54359404
52MYC_18940864_ChIP-ChIP_HL60_Human1.50321429
53TAF15_26573619_Chip-Seq_HEK293_Human1.49311241
54ERG_20887958_ChIP-Seq_HPC-7_Mouse1.45615052
55PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.44382389
56MYCN_18555785_ChIP-Seq_MESCs_Mouse1.44252621
57E2F1_21310950_ChIP-Seq_MCF-7_Human1.42123247
58FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.40903724
59TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.38638565
60IRF1_19129219_ChIP-ChIP_H3396_Human1.35641527
61ESR1_15608294_ChIP-ChIP_MCF-7_Human1.34790452
62FOXM1_23109430_ChIP-Seq_U2OS_Human1.33599688
63FUS_26573619_Chip-Seq_HEK293_Human1.33488522
64VDR_22108803_ChIP-Seq_LS180_Human1.30358772
65AR_21909140_ChIP-Seq_LNCAP_Human1.30004258
66IGF1R_20145208_ChIP-Seq_DFB_Human1.27934892
67ZFX_18555785_ChIP-Seq_MESCs_Mouse1.26891950
68PCGF2_27294783_Chip-Seq_ESCs_Mouse1.25891028
69CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.24876637
70* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.20348415
71CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.18302051
72GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.18059001
73NANOG_18555785_ChIP-Seq_MESCs_Mouse1.15456126
74GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14690940
75EWS_26573619_Chip-Seq_HEK293_Human1.13704144
76NANOG_16153702_ChIP-ChIP_HESCs_Human1.08922492
77SOX17_20123909_ChIP-Seq_XEN_Mouse1.08765022
78KDM5A_27292631_Chip-Seq_BREAST_Human1.05002534
79CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.04888533
80SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.04120892
81SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.03149291
82GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.01726410
83CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.01630199
84RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.01445533
85GATA1_22025678_ChIP-Seq_K562_Human1.00423824
86P300_19829295_ChIP-Seq_ESCs_Human1.00026568
87POU5F1_16153702_ChIP-ChIP_HESCs_Human0.98948847
88NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.96949997
89CIITA_25753668_ChIP-Seq_RAJI_Human0.96163392
90ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.96163309
91ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.95294319
92CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.93315372
93SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.92603467
94BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.91812034
95ELK1_22589737_ChIP-Seq_MCF10A_Human0.89767326
96GBX2_23144817_ChIP-Seq_PC3_Human0.87244428
97CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.86458026
98CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.86433477
99HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.84370941
100CTCF_18555785_ChIP-Seq_MESCs_Mouse0.83644224
101NOTCH1_21737748_ChIP-Seq_TLL_Human0.82775332
102IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.82363329
103ER_23166858_ChIP-Seq_MCF-7_Human0.82038654
104SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.81316941
105EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.81304477
106EZH2_27294783_Chip-Seq_NPCs_Mouse0.81004308
107HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.79324554
108TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.78038848
109FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.77876880
110ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.77152491
111KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.77070914
112TP53_22573176_ChIP-Seq_HFKS_Human0.75628574
113SOX2_16153702_ChIP-ChIP_HESCs_Human0.75012056
114SUZ12_27294783_Chip-Seq_NPCs_Mouse0.74900481
115MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.74525520
116E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.73985917
117ELF5_23300383_ChIP-Seq_T47D_Human0.73843284
118* BRD4_25478319_ChIP-Seq_HGPS_Human0.73244664
119TFEB_21752829_ChIP-Seq_HELA_Human0.72059354
120* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71475130
121POU3F2_20337985_ChIP-ChIP_501MEL_Human0.69223512
122PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.68916499
123SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.68847179
124CTBP1_25329375_ChIP-Seq_LNCAP_Human0.67086596
125ZFP57_27257070_Chip-Seq_ESCs_Mouse0.66962429
126SALL4_22934838_ChIP-ChIP_CD34+_Human0.66944672
127SOX2_18555785_ChIP-Seq_MESCs_Mouse0.63087085

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004147_increased_porphyrin_level4.00670440
2MP0003880_abnormal_central_pattern3.95397116
3MP0001529_abnormal_vocalization3.78765205
4MP0010094_abnormal_chromosome_stability3.07803675
5MP0003656_abnormal_erythrocyte_physiolo2.98686667
6MP0008057_abnormal_DNA_replication2.93621942
7MP0008877_abnormal_DNA_methylation2.78984333
8MP0008058_abnormal_DNA_repair2.73068252
9MP0006035_abnormal_mitochondrial_morpho2.64588604
10MP0003693_abnormal_embryo_hatching2.60049247
11MP0004957_abnormal_blastocyst_morpholog2.58873331
12MP0003890_abnormal_embryonic-extraembry2.53411061
13MP0006036_abnormal_mitochondrial_physio2.42223334
14MP0002736_abnormal_nociception_after2.40080403
15MP0003111_abnormal_nucleus_morphology2.26104998
16MP0003950_abnormal_plasma_membrane2.19496490
17MP0001905_abnormal_dopamine_level2.12519117
18MP0003123_paternal_imprinting2.07208864
19MP0001188_hyperpigmentation2.03611369
20MP0001968_abnormal_touch/_nociception2.02539499
21MP0003077_abnormal_cell_cycle1.98751976
22MP0002876_abnormal_thyroid_physiology1.97289405
23MP0009697_abnormal_copulation1.96014217
24MP0003941_abnormal_skin_development1.95870842
25MP0002396_abnormal_hematopoietic_system1.94771504
26MP0010352_gastrointestinal_tract_polyps1.93090069
27MP0009745_abnormal_behavioral_response1.89522756
28MP0003786_premature_aging1.87400987
29MP0005408_hypopigmentation1.86529811
30MP0003806_abnormal_nucleotide_metabolis1.82373145
31MP0005646_abnormal_pituitary_gland1.82005534
32MP0003787_abnormal_imprinting1.78508083
33MP0009046_muscle_twitch1.75445120
34MP0002938_white_spotting1.74702378
35MP0002064_seizures1.72758928
36MP0004142_abnormal_muscle_tone1.71439067
37MP0006072_abnormal_retinal_apoptosis1.70821118
38MP0002102_abnormal_ear_morphology1.68231718
39MP0005075_abnormal_melanosome_morpholog1.67944364
40MP0006054_spinal_hemorrhage1.66614372
41MP0003186_abnormal_redox_activity1.66515907
42MP0008007_abnormal_cellular_replicative1.66182738
43MP0001764_abnormal_homeostasis1.65684244
44MP0009379_abnormal_foot_pigmentation1.62904266
45MP0006276_abnormal_autonomic_nervous1.55291478
46MP0002234_abnormal_pharynx_morphology1.54116659
47MP0008872_abnormal_physiological_respon1.49155664
48MP0010307_abnormal_tumor_latency1.48357558
49MP0003635_abnormal_synaptic_transmissio1.47709985
50MP0000427_abnormal_hair_cycle1.46446237
51MP0002572_abnormal_emotion/affect_behav1.42007749
52MP0001501_abnormal_sleep_pattern1.41871726
53MP0001730_embryonic_growth_arrest1.35762482
54MP0002132_abnormal_respiratory_system1.35548190
55MP0003937_abnormal_limbs/digits/tail_de1.35033549
56MP0003121_genomic_imprinting1.34826599
57MP0001661_extended_life_span1.32064849
58MP0002063_abnormal_learning/memory/cond1.32055856
59MP0005266_abnormal_metabolism1.27927691
60MP0001697_abnormal_embryo_size1.25739623
61MP0008875_abnormal_xenobiotic_pharmacok1.25047467
62MP0002272_abnormal_nervous_system1.23572066
63MP0008932_abnormal_embryonic_tissue1.23232492
64MP0002139_abnormal_hepatobiliary_system1.22857731
65MP0006292_abnormal_olfactory_placode1.22273104
66MP0002084_abnormal_developmental_patter1.20002317
67MP0003122_maternal_imprinting1.18924839
68MP0005253_abnormal_eye_physiology1.17530054
69MP0001293_anophthalmia1.16446501
70MP0000490_abnormal_crypts_of1.16292561
71MP0000647_abnormal_sebaceous_gland1.15738098
72MP0000358_abnormal_cell_content/1.15414861
73MP0004924_abnormal_behavior1.14835975
74MP0005386_behavior/neurological_phenoty1.14835975
75MP0003183_abnormal_peptide_metabolism1.14397980
76MP0001984_abnormal_olfaction1.14153096
77MP0005394_taste/olfaction_phenotype1.14045980
78MP0005499_abnormal_olfactory_system1.14045980
79MP0002067_abnormal_sensory_capabilities1.14040574
80MP0003718_maternal_effect1.14009496
81MP0001672_abnormal_embryogenesis/_devel1.13820656
82MP0005380_embryogenesis_phenotype1.13820656
83MP0002822_catalepsy1.12350724
84MP0003567_abnormal_fetal_cardiomyocyte1.11138943
85MP0005379_endocrine/exocrine_gland_phen1.10088616
86MP0002735_abnormal_chemical_nociception1.09277553
87MP0005395_other_phenotype1.08142804
88MP0000516_abnormal_urinary_system1.08041027
89MP0005367_renal/urinary_system_phenotyp1.08041027
90MP0005376_homeostasis/metabolism_phenot1.07183442
91MP0003943_abnormal_hepatobiliary_system1.06751901
92MP0003011_delayed_dark_adaptation1.05346683
93MP0002085_abnormal_embryonic_tissue1.04417324
94MP0003879_abnormal_hair_cell0.97848650
95MP0001986_abnormal_taste_sensitivity0.97706730
96MP0000372_irregular_coat_pigmentation0.97602226
97MP0005397_hematopoietic_system_phenotyp0.96001076
98MP0001545_abnormal_hematopoietic_system0.96001076
99MP0005332_abnormal_amino_acid0.95457060
100MP0008789_abnormal_olfactory_epithelium0.93038455
101MP0000653_abnormal_sex_gland0.92896431
102MP0002734_abnormal_mechanical_nocicepti0.92665584
103MP0004808_abnormal_hematopoietic_stem0.92376608
104MP0002088_abnormal_embryonic_growth/wei0.91729940
105MP0002090_abnormal_vision0.91387545
106MP0003136_yellow_coat_color0.91066661
107MP0008995_early_reproductive_senescence0.90982417
108MP0003252_abnormal_bile_duct0.90537987
109MP0001440_abnormal_grooming_behavior0.89807521
110MP0005636_abnormal_mineral_homeostasis0.89756036
111MP0002163_abnormal_gland_morphology0.89395901
112MP0003984_embryonic_growth_retardation0.89179299
113MP0001145_abnormal_male_reproductive0.88256627
114MP0002080_prenatal_lethality0.87349928
115MP0000689_abnormal_spleen_morphology0.86660716
116MP0002332_abnormal_exercise_endurance0.84769643
117MP0001324_abnormal_eye_pigmentation0.84421429
118MP0001119_abnormal_female_reproductive0.84023386
119MP0001286_abnormal_eye_development0.83446503
120MP0001919_abnormal_reproductive_system0.83426710
121MP0001664_abnormal_digestion0.82505672
122MP0002019_abnormal_tumor_incidence0.82401553
123MP0004859_abnormal_synaptic_plasticity0.81477803
124MP0002009_preneoplasia0.81158576
125MP0002638_abnormal_pupillary_reflex0.80753939
126MP0003195_calcinosis0.80668408
127MP0005410_abnormal_fertilization0.80638758
128MP0002160_abnormal_reproductive_system0.80091138
129MP0002837_dystrophic_cardiac_calcinosis0.79242403
130MP0003763_abnormal_thymus_physiology0.78971048
131MP0005220_abnormal_exocrine_pancreas0.78078730
132MP0002877_abnormal_melanocyte_morpholog0.77685696
133MP0000313_abnormal_cell_death0.77433350
134MP0005171_absent_coat_pigmentation0.77235427
135MP0002722_abnormal_immune_system0.76983210
136MP0005084_abnormal_gallbladder_morpholo0.76910638
137MP0002398_abnormal_bone_marrow0.76620060
138MP0002751_abnormal_autonomic_nervous0.76195731
139MP0002111_abnormal_tail_morphology0.75388456
140MP0002557_abnormal_social/conspecific_i0.75383338
141MP0002086_abnormal_extraembryonic_tissu0.75324874
142MP0004215_abnormal_myocardial_fiber0.75137760
143MP0004197_abnormal_fetal_growth/weight/0.72174010
144MP0000350_abnormal_cell_proliferation0.71712156
145MP0003755_abnormal_palate_morphology0.70909783
146MP0002210_abnormal_sex_determination0.70433793
147MP0002233_abnormal_nose_morphology0.68059335
148MP0003868_abnormal_feces_composition0.67865005
149MP0002282_abnormal_trachea_morphology0.67563395
150MP0005365_abnormal_bile_salt0.67425361
151MP0005391_vision/eye_phenotype0.66946810
152MP0005389_reproductive_system_phenotype0.66392834
153MP0001929_abnormal_gametogenesis0.66176677
154MP0009333_abnormal_splenocyte_physiolog0.66159977
155MP0005551_abnormal_eye_electrophysiolog0.66128554
156MP0003119_abnormal_digestive_system0.66031942
157MP0000428_abnormal_craniofacial_morphol0.65722413
158MP0002095_abnormal_skin_pigmentation0.62881256
159MP0002429_abnormal_blood_cell0.58435177

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the heme biosynthetic pathway (HP:0010472)5.34349901
2Acute necrotizing encephalopathy (HP:0006965)5.14869603
3Abnormal mitochondria in muscle tissue (HP:0008316)5.05534480
4Mitochondrial inheritance (HP:0001427)4.74429047
5Increased CSF lactate (HP:0002490)4.45687480
6Hepatocellular necrosis (HP:0001404)4.43599861
7Progressive macrocephaly (HP:0004481)4.25317343
8Acute encephalopathy (HP:0006846)4.19889666
9Abnormal number of erythroid precursors (HP:0012131)4.10888106
10Abnormality of cells of the erythroid lineage (HP:0012130)4.10327561
11Birth length less than 3rd percentile (HP:0003561)4.03030362
12Abnormality of glycolysis (HP:0004366)3.68973263
13Increased serum pyruvate (HP:0003542)3.68973263
14Decreased activity of mitochondrial respiratory chain (HP:0008972)3.67104724
15Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.67104724
16Hepatic necrosis (HP:0002605)3.65711334
17Aplastic anemia (HP:0001915)3.55021223
18Increased serum lactate (HP:0002151)3.44539740
19Lactic acidosis (HP:0003128)3.30726549
203-Methylglutaconic aciduria (HP:0003535)3.29770681
21Focal motor seizures (HP:0011153)3.22397497
22Aplasia/Hypoplasia of the uvula (HP:0010293)3.17779025
23Colon cancer (HP:0003003)3.17000888
24Exercise intolerance (HP:0003546)2.98597420
25Cerebral edema (HP:0002181)2.97857687
26Abnormality of the ileum (HP:0001549)2.96905634
27Increased hepatocellular lipid droplets (HP:0006565)2.95680008
28Abnormality of alanine metabolism (HP:0010916)2.94970917
29Hyperalaninemia (HP:0003348)2.94970917
30Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.94970917
31Microvesicular hepatic steatosis (HP:0001414)2.88756144
32Epileptic encephalopathy (HP:0200134)2.87707333
33Increased intramyocellular lipid droplets (HP:0012240)2.83961655
34Abnormal protein glycosylation (HP:0012346)2.80432487
35Abnormal glycosylation (HP:0012345)2.80432487
36Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.80432487
37Abnormal protein N-linked glycosylation (HP:0012347)2.80432487
38Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.79303588
39Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.77627434
40Reticulocytopenia (HP:0001896)2.74572799
41Abnormal hair whorl (HP:0010721)2.73359743
42Oral leukoplakia (HP:0002745)2.71833924
43Optic disc pallor (HP:0000543)2.70147271
44Pancreatic islet-cell hyperplasia (HP:0004510)2.69003300
45Hyperventilation (HP:0002883)2.68158086
46Respiratory failure (HP:0002878)2.66356405
47Abnormality of methionine metabolism (HP:0010901)2.64933359
48Lipid accumulation in hepatocytes (HP:0006561)2.60552847
49Poor suck (HP:0002033)2.60241476
50Cholecystitis (HP:0001082)2.60002782
51Abnormal gallbladder physiology (HP:0012438)2.60002782
52Methylmalonic acidemia (HP:0002912)2.54531908
53Hypoglycemic coma (HP:0001325)2.54298157
54Reduced antithrombin III activity (HP:0001976)2.53322881
55Macrocytic anemia (HP:0001972)2.49959913
56Hyperinsulinemic hypoglycemia (HP:0000825)2.49657684
57Agnosia (HP:0010524)2.47366804
58IgM deficiency (HP:0002850)2.45154767
59Leukodystrophy (HP:0002415)2.44990548
60Small hand (HP:0200055)2.41760796
61Abnormality of DNA repair (HP:0003254)2.41530142
62Pallor (HP:0000980)2.41189174
63Breast hypoplasia (HP:0003187)2.39051024
64Abnormal spermatogenesis (HP:0008669)2.37502057
65Type I transferrin isoform profile (HP:0003642)2.37174886
66Delusions (HP:0000746)2.37167938
67Protruding tongue (HP:0010808)2.36089088
68Hypoplasia of the capital femoral epiphysis (HP:0003090)2.34682667
69Respiratory difficulties (HP:0002880)2.32697585
70Hypobetalipoproteinemia (HP:0003563)2.31234428
71Increased muscle lipid content (HP:0009058)2.30117306
72Hypoglycemic seizures (HP:0002173)2.27793854
73Neoplasm of the adrenal gland (HP:0100631)2.27681833
74Abnormality of endocrine pancreas physiology (HP:0012093)2.27170670
75Abnormality of the pancreatic islet cells (HP:0006476)2.27170670
76Gonadotropin excess (HP:0000837)2.25259402
77Renal Fanconi syndrome (HP:0001994)2.24582232
78Pancreatic cysts (HP:0001737)2.23826912
79Hypoplastic pelvis (HP:0008839)2.23031661
80Nephrogenic diabetes insipidus (HP:0009806)2.20660883
81Exertional dyspnea (HP:0002875)2.20264883
82True hermaphroditism (HP:0010459)2.19319589
83Abnormality of chromosome stability (HP:0003220)2.17794161
84Atonic seizures (HP:0010819)2.16671880
85Prominent metopic ridge (HP:0005487)2.16631579
86Emotional lability (HP:0000712)2.16307804
87Congenital primary aphakia (HP:0007707)2.16043991
88Glycosuria (HP:0003076)2.16010942
89Abnormality of urine glucose concentration (HP:0011016)2.16010942
90Glioma (HP:0009733)2.15929081
91CNS demyelination (HP:0007305)2.15390518
92Pancytopenia (HP:0001876)2.13954513
93Chromsome breakage (HP:0040012)2.13119197
94Medial flaring of the eyebrow (HP:0010747)2.12634241
95Abnormality of the preputium (HP:0100587)2.12204627
96Abnormal lung lobation (HP:0002101)2.10063000
97Symptomatic seizures (HP:0011145)2.09549915
98Small intestinal stenosis (HP:0012848)2.09420116
99Duodenal stenosis (HP:0100867)2.09420116
100Pancreatic fibrosis (HP:0100732)2.06120859
101Degeneration of anterior horn cells (HP:0002398)2.05923920
102Abnormality of the anterior horn cell (HP:0006802)2.05923920
103Gait imbalance (HP:0002141)2.05715835
104Volvulus (HP:0002580)2.05301381
105Ragged-red muscle fibers (HP:0003200)2.05092741
106Abnormality of the pons (HP:0007361)2.04855924
107Sloping forehead (HP:0000340)2.04837118
108Renal cortical cysts (HP:0000803)2.04530941
109Entropion (HP:0000621)2.01837905
110Abnormality of aspartate family amino acid metabolism (HP:0010899)2.01155800
111Hypoplasia of the pons (HP:0012110)2.00820080
112Postnatal microcephaly (HP:0005484)2.00691969
113Ependymoma (HP:0002888)2.00510479
114Absent thumb (HP:0009777)1.99196462
115Thrombocytosis (HP:0001894)1.98024164
116Hyperglycinemia (HP:0002154)1.97908633
117Cerebral hypomyelination (HP:0006808)1.97408002
118Poikilocytosis (HP:0004447)1.97331743
119Ketoacidosis (HP:0001993)1.97282018
120Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.96780139
121Absent epiphyses (HP:0010577)1.96780139
122Abnormality of serum amino acid levels (HP:0003112)1.96081390
123Adrenal hypoplasia (HP:0000835)1.95962551
124Abnormality of the labia minora (HP:0012880)1.95668058
125Abnormality of the astrocytes (HP:0100707)1.94122615
126Astrocytoma (HP:0009592)1.94122615
127Irregular epiphyses (HP:0010582)1.93414219
128Methylmalonic aciduria (HP:0012120)1.93159978
129Abnormality of aromatic amino acid family metabolism (HP:0004338)1.92775330
130Secondary amenorrhea (HP:0000869)1.91204469
131Long foot (HP:0001833)1.90326303
132Myelodysplasia (HP:0002863)1.90256367
133Abnormality of reticulocytes (HP:0004312)1.89928409
134Chromosomal breakage induced by crosslinking agents (HP:0003221)1.89001483
135Gliosis (HP:0002171)1.88799915
136Abnormality of the metopic suture (HP:0005556)1.88121771
137Febrile seizures (HP:0002373)1.87768324
138Abnormality of the duodenum (HP:0002246)1.86748054
139Progressive inability to walk (HP:0002505)1.86495876
140CNS hypomyelination (HP:0003429)1.85611410
141Type 2 muscle fiber atrophy (HP:0003554)1.84467806
142Neoplasm of the adrenal cortex (HP:0100641)1.84453834
143Type II lissencephaly (HP:0007260)1.84385037
144Cholelithiasis (HP:0001081)1.81883135
145Female pseudohermaphroditism (HP:0010458)1.81706655
146Abnormal number of incisors (HP:0011064)1.81587772
147Brushfield spots (HP:0001088)1.80275420
148Unsteady gait (HP:0002317)1.79921926
149Abnormality of the carotid arteries (HP:0005344)1.77805007
150Poor head control (HP:0002421)1.77526111
151Thyroid-stimulating hormone excess (HP:0002925)1.75237030
152Hypothermia (HP:0002045)1.75166369
153Sensory axonal neuropathy (HP:0003390)1.75133670
154Abnormality of the renal cortex (HP:0011035)1.73636393
155Sclerocornea (HP:0000647)1.73491796
156Clubbing of toes (HP:0100760)1.73431867
157Megaloblastic anemia (HP:0001889)1.70787335
158Cellular immunodeficiency (HP:0005374)1.69995216
159Poor coordination (HP:0002370)1.68429888
160Meckel diverticulum (HP:0002245)1.66523700
161Bone marrow hypocellularity (HP:0005528)1.66381400
162Premature graying of hair (HP:0002216)1.65742131
16311 pairs of ribs (HP:0000878)1.65680693
164Rough bone trabeculation (HP:0100670)1.65251608
165Hyperbilirubinemia (HP:0002904)1.65019807
166Cutaneous photosensitivity (HP:0000992)1.64888678

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.53749405
2CCNB13.52960999
3MAP3K123.51032137
4STK163.38331555
5CDK193.28893925
6BUB13.09741012
7EIF2AK12.81749711
8CDC72.62681930
9TSSK62.59593159
10DAPK12.58739859
11TRIM282.58459763
12PBK2.52009142
13ZAK2.42761240
14WEE12.36300131
15FRK2.29206673
16MAP2K72.24548282
17NUAK11.94863348
18NME11.87004888
19NME21.85258582
20PLK21.84317531
21VRK11.82393908
22MAP3K41.72768473
23ACVR1B1.68051419
24PDK21.67220848
25CDK81.66413421
26WNK31.59077402
27MKNK21.56571978
28MST41.56211810
29NEK11.51347027
30TLK11.51316766
31SRPK11.50658435
32MKNK11.45904430
33VRK21.35350218
34STK31.31311491
35ERBB31.30863500
36SIK31.30531907
37GRK11.26553479
38BRSK21.22428200
39PASK1.20478047
40EIF2AK31.20451029
41ADRBK21.20199695
42CLK11.14021747
43TAF11.13826716
44AKT31.13633960
45LATS11.11809337
46CHEK21.11612775
47BCR1.09973585
48CSNK1G11.08203919
49GRK61.08166593
50ERBB41.07989012
51STK38L1.05528297
52CSNK1G31.03957576
53STK241.03131171
54TNK21.00485535
55PLK30.99978561
56BRSK10.98944522
57PLK40.97045726
58ATR0.95890370
59NEK90.93062669
60MAP4K20.92433927
61MAPKAPK30.90361693
62ATM0.90005320
63DAPK20.89951389
64BRAF0.89680068
65BMPR1B0.88333189
66PLK10.88091735
67MAP2K40.87691210
68NEK20.86344909
69OXSR10.84726621
70GRK50.84098106
71CSNK1A1L0.83885835
72TIE10.83539064
73MYLK0.83113507
74MELK0.80887729
75CSNK1G20.80872954
76NTRK30.80081657
77TTK0.79177302
78GRK70.78464649
79TGFBR10.77160067
80AURKB0.74711151
81TNIK0.73860392
82RPS6KB20.72835666
83BMPR20.70983488
84BCKDK0.69423386
85STK100.68609783
86AURKA0.68365103
87BRD40.67876904
88WNK40.66339027
89TEC0.65384132
90PRPF4B0.65201806
91CDK180.63560678
92PNCK0.62627700
93LIMK10.59196713
94PRKCG0.59168204
95ADRBK10.59011559
96STK40.58677327
97CDK150.56952896
98CSNK2A20.56757871
99MINK10.56743959
100DYRK1A0.56461417
101CSNK2A10.56099299
102YES10.56088313
103ALK0.55787611
104MAPKAPK50.55046543
105SYK0.53120040
106STK390.53086562
107CDK11A0.52861460
108PDK30.50363416
109PDK40.50363416
110KIT0.50331170
111CDK70.49600505
112PTK2B0.49351036
113EIF2AK20.49129700
114MAP3K60.48439727
115IRAK40.47792498
116CDK30.47079859
117EPHA40.46885454
118CDK140.46706433
119FES0.46619844
120TGFBR20.44705423
121DYRK30.44666262
122SCYL20.44273242
123FGFR10.42436960
124TXK0.41523558
125FLT30.40702837
126CDK40.40410207
127PIM10.40244600
128CSNK1E0.40022766
129PRKCE0.40008320
130PRKDC0.39036210
131PIM20.36649501
132NLK0.36590281
133MET0.34555948
134SGK20.34521670
135DAPK30.34508171
136CDK10.34349306
137MAP3K110.33727799
138CSF1R0.33499947
139PRKCI0.33145749
140RIPK40.33013002
141PAK40.32775215
142LYN0.31540041
143RPS6KB10.30468813
144MAPK40.27961543
145CHEK10.27920533
146CSNK1D0.27480445
147CAMKK20.27352408
148CSNK1A10.26244983

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.13437036
2Proteasome_Homo sapiens_hsa030503.83733369
3Oxidative phosphorylation_Homo sapiens_hsa001903.76523494
4Ribosome_Homo sapiens_hsa030103.76283321
5Mismatch repair_Homo sapiens_hsa034303.29469440
6Parkinsons disease_Homo sapiens_hsa050123.10676655
7RNA polymerase_Homo sapiens_hsa030202.77743627
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.45770802
9Collecting duct acid secretion_Homo sapiens_hsa049662.45001163
10Pyrimidine metabolism_Homo sapiens_hsa002402.36659126
11Huntingtons disease_Homo sapiens_hsa050162.34151373
12Homologous recombination_Homo sapiens_hsa034402.23137632
13Spliceosome_Homo sapiens_hsa030402.18455054
14Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.14424057
15Steroid biosynthesis_Homo sapiens_hsa001002.14147927
16Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008602.11930702
17Alzheimers disease_Homo sapiens_hsa050102.11222400
18Nucleotide excision repair_Homo sapiens_hsa034202.10090807
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.03674025
20Base excision repair_Homo sapiens_hsa034101.91800626
21One carbon pool by folate_Homo sapiens_hsa006701.91239271
22Non-homologous end-joining_Homo sapiens_hsa034501.86381765
23Nicotine addiction_Homo sapiens_hsa050331.80886903
24Vitamin B6 metabolism_Homo sapiens_hsa007501.76754470
25Selenocompound metabolism_Homo sapiens_hsa004501.75092489
26Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.75076166
27Synaptic vesicle cycle_Homo sapiens_hsa047211.71456159
28RNA transport_Homo sapiens_hsa030131.60518599
29Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.58179942
30Fanconi anemia pathway_Homo sapiens_hsa034601.53756502
31Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.49576800
32Protein export_Homo sapiens_hsa030601.44505926
33Purine metabolism_Homo sapiens_hsa002301.42134806
34Cysteine and methionine metabolism_Homo sapiens_hsa002701.37468892
35RNA degradation_Homo sapiens_hsa030181.36685206
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.36559946
37Cell cycle_Homo sapiens_hsa041101.33393890
38Maturity onset diabetes of the young_Homo sapiens_hsa049501.31885884
39Vibrio cholerae infection_Homo sapiens_hsa051101.27445815
40Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.25049012
41Pyruvate metabolism_Homo sapiens_hsa006201.24444264
42Basal transcription factors_Homo sapiens_hsa030221.21017672
432-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.20684398
44Butanoate metabolism_Homo sapiens_hsa006501.17866647
45Biosynthesis of amino acids_Homo sapiens_hsa012300.99354438
46Cyanoamino acid metabolism_Homo sapiens_hsa004600.97630501
47Systemic lupus erythematosus_Homo sapiens_hsa053220.94897573
48Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.92253207
49Primary bile acid biosynthesis_Homo sapiens_hsa001200.89436166
50SNARE interactions in vesicular transport_Homo sapiens_hsa041300.89232242
51Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.87523906
52Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.86529133
53Carbon metabolism_Homo sapiens_hsa012000.84621959
54Pentose and glucuronate interconversions_Homo sapiens_hsa000400.84059087
55Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.81286236
56Fatty acid metabolism_Homo sapiens_hsa012120.80515517
57Drug metabolism - other enzymes_Homo sapiens_hsa009830.77902378
58Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.77706409
59TGF-beta signaling pathway_Homo sapiens_hsa043500.77094797
60Glutathione metabolism_Homo sapiens_hsa004800.75550649
61Folate biosynthesis_Homo sapiens_hsa007900.73531153
62* Metabolic pathways_Homo sapiens_hsa011000.73459355
63Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.71010172
64Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.67410198
65Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.67222954
66Phenylalanine metabolism_Homo sapiens_hsa003600.66557248
67Vitamin digestion and absorption_Homo sapiens_hsa049770.64307978
68Fructose and mannose metabolism_Homo sapiens_hsa000510.62991098
69Pentose phosphate pathway_Homo sapiens_hsa000300.62458605
70Sphingolipid metabolism_Homo sapiens_hsa006000.62277094
71Cardiac muscle contraction_Homo sapiens_hsa042600.62018576
72Rheumatoid arthritis_Homo sapiens_hsa053230.60812432
73Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.60504955
74Tryptophan metabolism_Homo sapiens_hsa003800.59300266
75Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.57634719
76Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.56607530
77Epstein-Barr virus infection_Homo sapiens_hsa051690.55225017
78Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.54912572
79Alcoholism_Homo sapiens_hsa050340.52392484
80Phagosome_Homo sapiens_hsa041450.50382601
81Lysine degradation_Homo sapiens_hsa003100.50068727
82Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.49988536
83Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.49866999
84mRNA surveillance pathway_Homo sapiens_hsa030150.49420321
85Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.48661949
86Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.47484688
87Sulfur relay system_Homo sapiens_hsa041220.46180017
88Sulfur metabolism_Homo sapiens_hsa009200.45429491
89Galactose metabolism_Homo sapiens_hsa000520.45422710
90Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.44952821
91Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.44664741
92N-Glycan biosynthesis_Homo sapiens_hsa005100.43777569
93Fatty acid elongation_Homo sapiens_hsa000620.43771046
94Morphine addiction_Homo sapiens_hsa050320.43348585
95Amphetamine addiction_Homo sapiens_hsa050310.43174970
96Chemical carcinogenesis_Homo sapiens_hsa052040.42042719
97Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.41467938
98Peroxisome_Homo sapiens_hsa041460.39778669
99p53 signaling pathway_Homo sapiens_hsa041150.39071287
100Tyrosine metabolism_Homo sapiens_hsa003500.38044753
101Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.37900082
102Fatty acid degradation_Homo sapiens_hsa000710.37859329
103Hippo signaling pathway_Homo sapiens_hsa043900.36989595
104* Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.36470731
105Olfactory transduction_Homo sapiens_hsa047400.36185303
106Oocyte meiosis_Homo sapiens_hsa041140.34618637
107Arginine and proline metabolism_Homo sapiens_hsa003300.34536766
108Taste transduction_Homo sapiens_hsa047420.34354367
109Fatty acid biosynthesis_Homo sapiens_hsa000610.33505777
110Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.31693792
111Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.29704222
112Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.29687484
113Type I diabetes mellitus_Homo sapiens_hsa049400.29645643
114Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.29558543
115Nitrogen metabolism_Homo sapiens_hsa009100.28518200
116Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.28278378
117GABAergic synapse_Homo sapiens_hsa047270.28200182
118Steroid hormone biosynthesis_Homo sapiens_hsa001400.26025397
119Retinol metabolism_Homo sapiens_hsa008300.24408418
120Regulation of autophagy_Homo sapiens_hsa041400.23855276
121Glycerolipid metabolism_Homo sapiens_hsa005610.23177070
122Long-term potentiation_Homo sapiens_hsa047200.21740183
123Propanoate metabolism_Homo sapiens_hsa006400.20178369
124Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.20017853
125Herpes simplex infection_Homo sapiens_hsa051680.19796758
126Phototransduction_Homo sapiens_hsa047440.19028182
127Circadian entrainment_Homo sapiens_hsa047130.18417107
128Wnt signaling pathway_Homo sapiens_hsa043100.17694963
129Legionellosis_Homo sapiens_hsa051340.17519665
130beta-Alanine metabolism_Homo sapiens_hsa004100.16911097
131Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.15346180
132Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.14445863
133Calcium signaling pathway_Homo sapiens_hsa040200.12721497
134Dopaminergic synapse_Homo sapiens_hsa047280.10646269

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