MYLIP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The ERM protein family members ezrin, radixin, and moesin are cytoskeletal effector proteins linking actin to membrane-bound proteins at the cell surface. Myosin regulatory light chain interacting protein (MYLIP) is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowth. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G6.03257239
2positive regulation of gamma-delta T cell activation (GO:0046645)5.01124383
3regulation of interferon-beta biosynthetic process (GO:0045357)4.66936895
4antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.53234490
5antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.53234490
6positive regulation by symbiont of host defense response (GO:0052509)4.50985897
7modulation by symbiont of host defense response (GO:0052031)4.50985897
8modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.50985897
9modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.50985897
10positive regulation by organism of defense response of other organism involved in symbiotic interact4.50985897
11modulation by symbiont of host immune response (GO:0052553)4.50985897
12tolerance induction (GO:0002507)4.49343785
13macrophage activation involved in immune response (GO:0002281)4.43935283
14antigen processing and presentation of endogenous antigen (GO:0019883)4.33723377
15regulation of B cell receptor signaling pathway (GO:0050855)4.29649649
16microglial cell activation (GO:0001774)4.13147346
17detection of other organism (GO:0098543)4.02270688
18regulation of gamma-delta T cell differentiation (GO:0045586)4.01285257
19positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.94416239
20positive T cell selection (GO:0043368)3.89924162
21regulation of gamma-delta T cell activation (GO:0046643)3.87415967
22negative regulation of erythrocyte differentiation (GO:0045647)3.84173124
23negative thymic T cell selection (GO:0045060)3.83626442
24detection of bacterium (GO:0016045)3.83246129
25positive regulation of B cell differentiation (GO:0045579)3.77388323
26negative T cell selection (GO:0043383)3.76355226
27positive regulation of granulocyte differentiation (GO:0030854)3.71788365
28B cell receptor signaling pathway (GO:0050853)3.62669800
29positive regulation of interferon-alpha production (GO:0032727)3.62084118
30regulation of B cell differentiation (GO:0045577)3.53226333
31negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.48666191
32negative regulation of T-helper cell differentiation (GO:0045623)3.48666191
33negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.48563361
34regulation of interleukin-12 biosynthetic process (GO:0045075)3.46074653
35T cell selection (GO:0045058)3.43756344
36negative regulation of granulocyte differentiation (GO:0030853)3.43561221
37regulation of interferon-alpha production (GO:0032647)3.42439131
38negative regulation of T cell mediated immunity (GO:0002710)3.39119448
39negative regulation of lymphocyte mediated immunity (GO:0002707)3.37064689
40detection of external biotic stimulus (GO:0098581)3.35340493
41regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.33949063
42positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.33086201
43thymic T cell selection (GO:0045061)3.32276693
44cellular response to zinc ion (GO:0071294)3.29654104
45positive regulation of antigen processing and presentation (GO:0002579)3.28694433
46cellular extravasation (GO:0045123)3.27254682
47macrophage activation (GO:0042116)3.25648293
48response to type I interferon (GO:0034340)3.14854431
49detection of molecule of bacterial origin (GO:0032490)3.12989383
50response to muramyl dipeptide (GO:0032495)3.10046520
51negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.09016403
52type I interferon signaling pathway (GO:0060337)3.07777053
53cellular response to type I interferon (GO:0071357)3.07777053
54germinal center formation (GO:0002467)3.07543188
55negative regulation of cell killing (GO:0031342)3.07324769
56negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.07324769
57neutrophil activation involved in immune response (GO:0002283)3.06157699
58immunoglobulin mediated immune response (GO:0016064)3.05029276
59neutrophil mediated immunity (GO:0002446)3.02863925
60lymph vessel development (GO:0001945)3.01675590
61response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.00348677
62response to host (GO:0075136)3.00348677
63response to host defenses (GO:0052200)3.00348677
64T-helper cell differentiation (GO:0042093)2.97798737
65CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.97798737
66regulation of alpha-beta T cell proliferation (GO:0046640)2.97063867
67detection of biotic stimulus (GO:0009595)2.96586617
68response to host immune response (GO:0052572)2.94347418
69response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.94347418
70myeloid cell activation involved in immune response (GO:0002275)2.93223723
71G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.91648747
72cellular response to interleukin-15 (GO:0071350)2.91487829
73T cell homeostasis (GO:0043029)2.91261518
74interferon-gamma-mediated signaling pathway (GO:0060333)2.91150033
75JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.90813294
76production of molecular mediator involved in inflammatory response (GO:0002532)2.88450632
77regulation of granulocyte differentiation (GO:0030852)2.87793604
78histone H3-K36 demethylation (GO:0070544)2.87705058
79negative regulation of leukocyte mediated immunity (GO:0002704)2.87386929
80antigen processing and presentation via MHC class Ib (GO:0002475)2.85660544
81natural killer cell differentiation (GO:0001779)2.84705132
82regulation of T cell tolerance induction (GO:0002664)2.83887390
83positive regulation of chemokine secretion (GO:0090197)2.82573436
84neutrophil activation (GO:0042119)2.82309657
85mature B cell differentiation (GO:0002335)2.80724760
86regulation of regulatory T cell differentiation (GO:0045589)2.80424513
87histone H3-K4 trimethylation (GO:0080182)2.79680838
88positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.79327405
89interferon-gamma production (GO:0032609)2.76937298
90positive regulation of interferon-beta production (GO:0032728)2.75941490
91vascular endothelial growth factor signaling pathway (GO:0038084)2.75001373
92regulation of antigen processing and presentation (GO:0002577)2.74327059
93response to laminar fluid shear stress (GO:0034616)2.73006205
94antigen receptor-mediated signaling pathway (GO:0050851)2.71726888
95CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.71350655
96NIK/NF-kappaB signaling (GO:0038061)2.70864771
97regulation of germinal center formation (GO:0002634)2.70727930
98keratan sulfate catabolic process (GO:0042340)2.69692683
99I-kappaB phosphorylation (GO:0007252)2.69653029
100regulation of tolerance induction (GO:0002643)2.69421982
101positive thymic T cell selection (GO:0045059)2.69382667
102leukocyte degranulation (GO:0043299)2.68795561
103regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.67544078
104T cell migration (GO:0072678)2.66604312
105positive regulation of humoral immune response (GO:0002922)2.66201201
106positive regulation of B cell activation (GO:0050871)2.66137112
107defense response to protozoan (GO:0042832)2.65238280
108regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.64548003
109regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.63712939
110negative regulation of cAMP-mediated signaling (GO:0043951)2.63096134
111negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.62890283
112response to protozoan (GO:0001562)2.62674489
113myeloid dendritic cell activation (GO:0001773)2.62485886
114activated T cell proliferation (GO:0050798)2.62455558
115negative regulation of innate immune response (GO:0045824)2.62379966
116leukocyte cell-cell adhesion (GO:0007159)2.61800112
117granulocyte activation (GO:0036230)2.61373938
118positive regulation of isotype switching (GO:0045830)2.60902606
119negative regulation of phagocytosis (GO:0050765)2.60423370
120lymphocyte homeostasis (GO:0002260)2.60174389
121RNA destabilization (GO:0050779)2.59863488
122substrate-dependent cell migration (GO:0006929)2.56885890
123positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.55673240
124response to interleukin-15 (GO:0070672)2.54976062
125definitive hemopoiesis (GO:0060216)2.53996654
126myeloid leukocyte activation (GO:0002274)2.52612029
127hepatocyte apoptotic process (GO:0097284)2.51931581
128lipopolysaccharide-mediated signaling pathway (GO:0031663)2.51725716
129myeloid dendritic cell differentiation (GO:0043011)2.51243871
130mature B cell differentiation involved in immune response (GO:0002313)2.49919198
131positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.49315646
132angiogenesis involved in wound healing (GO:0060055)2.48607067
133positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.47996825
134regulation of RIG-I signaling pathway (GO:0039535)2.47210806
135leukocyte tethering or rolling (GO:0050901)2.46710033
136regulation of type I interferon-mediated signaling pathway (GO:0060338)2.45820849
137lymph node development (GO:0048535)2.44972327
138germ cell migration (GO:0008354)2.43178773
139leukocyte aggregation (GO:0070486)2.41328530
140respiratory burst (GO:0045730)2.41046644
141response to peptidoglycan (GO:0032494)2.40891180
142regulation of necroptotic process (GO:0060544)2.39543894
143negative regulation of interleukin-6 production (GO:0032715)2.39371791
144cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.39302318
145mannose metabolic process (GO:0006013)2.39203801
146negative regulation of B cell proliferation (GO:0030889)2.37368074
147negative regulation of stress fiber assembly (GO:0051497)2.36634838
148regulation of dendritic cell antigen processing and presentation (GO:0002604)2.31739913
149dendritic cell differentiation (GO:0097028)2.31494136
150negative regulation of interleukin-12 production (GO:0032695)2.30814982

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.28664817
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.72788647
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.19662057
4IRF8_21731497_ChIP-ChIP_J774_Mouse3.91131549
5BP1_19119308_ChIP-ChIP_Hs578T_Human3.63362621
6EGR1_19374776_ChIP-ChIP_THP-1_Human3.46258023
7IRF8_27001747_Chip-Seq_BMDM_Mouse3.36505305
8* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.34518139
9NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.26593327
10* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.06778756
11IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.01353337
12IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.00496606
13STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.85323448
14NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.83707401
15SCL_19346495_ChIP-Seq_HPC-7_Human2.70306420
16* RUNX_20019798_ChIP-Seq_JUKART_Human2.69392188
17GATA1_22025678_ChIP-Seq_K562_Human2.63663162
18STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.42574767
19FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.39600855
20MYB_21317192_ChIP-Seq_ERMYB_Mouse2.37914101
21BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.23512501
22SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.21371395
23MYC_22102868_ChIP-Seq_BL_Human2.13273050
24Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.12880157
25RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.11393623
26MAF_26560356_Chip-Seq_TH1_Human2.10556621
27* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.10076149
28VDR_21846776_ChIP-Seq_THP-1_Human2.09842815
29* BRD4_27068464_Chip-Seq_AML-cells_Mouse2.09251272
30TCF7_22412390_ChIP-Seq_EML_Mouse2.04276962
31* STAT4_19710469_ChIP-ChIP_TH1__Mouse2.01453542
32MYB_26560356_Chip-Seq_TH2_Human2.01166024
33KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.00743807
34KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.00743807
35KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.00743807
36VDR_24763502_ChIP-Seq_THP-1_Human1.97187379
37E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.88188993
38RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.82248812
39SPI1_23127762_ChIP-Seq_K562_Human1.79828392
40* MYB_26560356_Chip-Seq_TH1_Human1.79554473
41KDM2B_26808549_Chip-Seq_SUP-B15_Human1.77326778
42FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.75687834
43SPI1_23547873_ChIP-Seq_NB4_Human1.75323062
44GATA2_21666600_ChIP-Seq_HMVEC_Human1.71973637
45UTX_26944678_Chip-Seq_JUKART_Human1.69434958
46ELK3_25401928_ChIP-Seq_HUVEC_Human1.67530391
47RUNX1_22412390_ChIP-Seq_EML_Mouse1.66386336
48STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.54395066
49THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.54189784
50VDR_24787735_ChIP-Seq_THP-1_Human1.50047789
51SMAD_19615063_ChIP-ChIP_OVARY_Human1.49431937
52CLOCK_20551151_ChIP-Seq_293T_Human1.47684144
53KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.45339559
54* PU_27001747_Chip-Seq_BMDM_Mouse1.41905988
55KDM2B_26808549_Chip-Seq_DND41_Human1.41116061
56* PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.38130510
57KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.37810264
58TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.37638189
59VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.36714002
60ESR1_21235772_ChIP-Seq_MCF-7_Human1.33675103
61NOTCH1_21737748_ChIP-Seq_TLL_Human1.33052835
62* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.32312129
63* GATA3_27048872_Chip-Seq_THYMUS_Human1.30446825
64ESR1_20079471_ChIP-ChIP_T-47D_Human1.28744487
65* GATA3_26560356_Chip-Seq_TH2_Human1.28142247
66TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.26014717
67TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.25038828
68TP63_17297297_ChIP-ChIP_HaCaT_Human1.24507776
69SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.24461122
70MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.23567767
71ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.23440080
72CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.22318006
73TRIM28_21343339_ChIP-Seq_HEK293_Human1.20687307
74RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.19609781
75LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.18082360
76NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.17773944
77* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.17399883
78PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.17380388
79GATA1_19941827_ChIP-Seq_MEL_Mouse1.13512983
80LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.10669379
81RARG_19884340_ChIP-ChIP_MEFs_Mouse1.09102773
82CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.07782712
83* GATA2_19941826_ChIP-Seq_K562_Human1.06417666
84GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.04086369
85* FOXO3_23340844_ChIP-Seq_DLD1_Human1.02877668
86SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.02593990
87ESR2_21235772_ChIP-Seq_MCF-7_Human1.02305625
88KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.01955310
89* GATA1_19941826_ChIP-Seq_K562_Human1.00654873
90GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98917838
91GATA1_22383799_ChIP-Seq_G1ME_Mouse0.98643218
92CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.97982344
93CDX2_20551321_ChIP-Seq_CACO-2_Human0.97594677
94CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.97161071
95TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.96307151
96KDM2B_26808549_Chip-Seq_JURKAT_Human0.96138281
97MAF_26560356_Chip-Seq_TH2_Human0.95984176
98* GATA1_19941827_ChIP-Seq_MEL86_Mouse0.95573836
99CIITA_25753668_ChIP-Seq_RAJI_Human0.95494312
100* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.94996121
101SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.94433395
102CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.91855454
103* SMRT_27268052_Chip-Seq_Bcells_Human0.90813742
104* FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.89529188
105* NFIB_24661679_ChIP-Seq_LUNG_Mouse0.88955789
106ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.87668083
107CJUN_26792858_Chip-Seq_BT549_Human0.87360803
108P63_26484246_Chip-Seq_KERATINOCYTES_Human0.86854836
109* PPAR_26484153_Chip-Seq_NCI-H1993_Human0.85901956
110SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.85023107
111SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.85023107
112PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.81799851
113* NCOR1_26117541_ChIP-Seq_K562_Human0.81777609
114ETS1_22383799_ChIP-Seq_G1ME_Mouse0.81053653
115GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80816812
116FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.80815474
117PPARA_22158963_ChIP-Seq_LIVER_Mouse0.80427515
118CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.79296419
119PKCTHETA_26484144_Chip-Seq_BREAST_Human0.79123296
120PU.1_20513432_ChIP-Seq_Bcells_Mouse0.78671747
121PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.77081586
122CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.76330681
123FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.73121646

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.70810411
2MP0003724_increased_susceptibility_to2.85784287
3MP0000685_abnormal_immune_system2.75385101
4MP0005671_abnormal_response_to2.71184450
5MP0006082_CNS_inflammation2.68638646
6MP0001790_abnormal_immune_system2.62528649
7MP0005387_immune_system_phenotype2.62528649
8MP0001800_abnormal_humoral_immune2.61923664
9MP0009785_altered_susceptibility_to2.52243542
10MP0003303_peritoneal_inflammation2.48055323
11MP0003191_abnormal_cellular_cholesterol2.46714958
12MP0003436_decreased_susceptibility_to2.46113341
13MP0002452_abnormal_antigen_presenting2.41601352
14MP0002166_altered_tumor_susceptibility2.39267815
15MP0003300_gastrointestinal_ulcer2.31740479
16MP0004381_abnormal_hair_follicle2.30477254
17MP0002419_abnormal_innate_immunity2.24791673
18MP0005000_abnormal_immune_tolerance2.23346179
19MP0002723_abnormal_immune_serum2.21363472
20MP0005025_abnormal_response_to2.14162031
21MP0002420_abnormal_adaptive_immunity2.09971569
22MP0002148_abnormal_hypersensitivity_rea2.08834408
23MP0001819_abnormal_immune_cell2.08399808
24MP0006054_spinal_hemorrhage2.07897118
25MP0005058_abnormal_lysosome_morphology2.07130619
26MP0005464_abnormal_platelet_physiology2.02092550
27MP0002132_abnormal_respiratory_system1.98673215
28MP0010368_abnormal_lymphatic_system1.96595058
29MP0002396_abnormal_hematopoietic_system1.93828190
30MP0008057_abnormal_DNA_replication1.89292858
31MP0008438_abnormal_cutaneous_collagen1.84141761
32MP0002006_tumorigenesis1.81369714
33MP0001879_abnormal_lymphatic_vessel1.79022021
34MP0005075_abnormal_melanosome_morpholog1.78613517
35MP0001533_abnormal_skeleton_physiology1.76276574
36MP0002398_abnormal_bone_marrow1.71220271
37MP0009278_abnormal_bone_marrow1.70270587
38MP0003763_abnormal_thymus_physiology1.67358785
39MP0000716_abnormal_immune_system1.66831721
40MP0001873_stomach_inflammation1.66648014
41MP0004947_skin_inflammation1.62003761
42MP0000689_abnormal_spleen_morphology1.59692301
43MP0002405_respiratory_system_inflammati1.59379551
44MP0004510_myositis1.59111483
45MP0005451_abnormal_body_composition1.57927131
46MP0010155_abnormal_intestine_physiology1.57252689
47MP0002254_reproductive_system_inflammat1.54736779
48MP0008995_early_reproductive_senescence1.52925116
49MP0004808_abnormal_hematopoietic_stem1.52871641
50MP0003279_aneurysm1.51517429
51MP0003566_abnormal_cell_adhesion1.50841181
52MP0003045_fibrosis1.50091506
53MP0001845_abnormal_inflammatory_respons1.48790821
54MP0000343_altered_response_to1.48135538
55MP0003828_pulmonary_edema1.46340099
56MP0002722_abnormal_immune_system1.45251413
57MP0002998_abnormal_bone_remodeling1.40329492
58MP0001545_abnormal_hematopoietic_system1.39890523
59MP0005397_hematopoietic_system_phenotyp1.39890523
60MP0002429_abnormal_blood_cell1.36911940
61MP0003172_abnormal_lysosome_physiology1.35899400
62MP0001851_eye_inflammation1.34764722
63MP0002009_preneoplasia1.32487725
64MP0005275_abnormal_skin_tensile1.30940330
65MP0000465_gastrointestinal_hemorrhage1.30592220
66MP0002933_joint_inflammation1.29251427
67MP0008469_abnormal_protein_level1.28816326
68MP0008260_abnormal_autophagy1.27328359
69MP0004264_abnormal_extraembryonic_tissu1.26870146
70MP0000767_abnormal_smooth_muscle1.25704230
71MP0005023_abnormal_wound_healing1.22335853
72MP0003448_altered_tumor_morphology1.20479555
73MP0009764_decreased_sensitivity_to1.17028184
74MP0003656_abnormal_erythrocyte_physiolo1.16144032
75MP0009333_abnormal_splenocyte_physiolog1.12991651
76MP0008961_abnormal_basal_metabolism1.12851450
77MP0000703_abnormal_thymus_morphology1.12007690
78MP0001853_heart_inflammation1.11807720
79MP0002277_abnormal_respiratory_mucosa1.11393278
80MP0003075_altered_response_to1.10693556
81MP0005670_abnormal_white_adipose1.08170484
82MP0005390_skeleton_phenotype1.02624738
83MP0002138_abnormal_hepatobiliary_system1.01274352
84MP0005310_abnormal_salivary_gland1.00150180
85MP0000249_abnormal_blood_vessel0.99800841
86MP0003091_abnormal_cell_migration0.97507467
87MP0005166_decreased_susceptibility_to0.95811390
88MP0002928_abnormal_bile_duct0.95046016
89MP0005076_abnormal_cell_differentiation0.94907309
90MP0000858_altered_metastatic_potential0.94308891
91MP0001958_emphysema0.93437598
92MP0002136_abnormal_kidney_physiology0.91656963
93MP0009115_abnormal_fat_cell0.91369326
94MP0004185_abnormal_adipocyte_glucose0.90897678
95MP0004484_altered_response_of0.89044356
96MP0005164_abnormal_response_to0.87664817
97MP0003183_abnormal_peptide_metabolism0.84877934
98MP0004130_abnormal_muscle_cell0.84059815
99MP0004883_abnormal_blood_vessel0.82881369
100MP0009840_abnormal_foam_cell0.82738753
101MP0002060_abnormal_skin_morphology0.82525820
102MP0003795_abnormal_bone_structure0.82408516
103MP0009763_increased_sensitivity_to0.80336094
104MP0008004_abnormal_stomach_pH0.78308197
105MP0001915_intracranial_hemorrhage0.77811721
106MP0003705_abnormal_hypodermis_morpholog0.76276785
107MP0002796_impaired_skin_barrier0.76164243
108MP0005167_abnormal_blood-brain_barrier0.75660472
109MP0003453_abnormal_keratinocyte_physiol0.75646297
110MP0002019_abnormal_tumor_incidence0.73039195
111MP0000015_abnormal_ear_pigmentation0.72749036
112MP0008877_abnormal_DNA_methylation0.72566179
113MP0004272_abnormal_basement_membrane0.72402236
114MP0003646_muscle_fatigue0.72096472
115MP0005503_abnormal_tendon_morphology0.71282618
116MP0002135_abnormal_kidney_morphology0.68546970
117MP0001243_abnormal_dermal_layer0.67400012
118MP0003866_abnormal_defecation0.66669944
119MP0005666_abnormal_adipose_tissue0.66114401
120MP0010307_abnormal_tumor_latency0.65834764
121MP0005334_abnormal_fat_pad0.62598683
122MP0002332_abnormal_exercise_endurance0.62011828
123MP0000470_abnormal_stomach_morphology0.58022074
124MP0005375_adipose_tissue_phenotype0.56568669
125MP0003221_abnormal_cardiomyocyte_apopto0.54255776
126MP0006138_congestive_heart_failure0.54080887
127MP0005647_abnormal_sex_gland0.52794399
128MP0005535_abnormal_body_temperature0.52133886

Predicted human phenotypes

RankGene SetZ-score
1Systemic lupus erythematosus (HP:0002725)4.64974225
2Stomatitis (HP:0010280)4.57813111
3Eczematoid dermatitis (HP:0000976)4.37572992
4Recurrent abscess formation (HP:0002722)4.18924178
5Hematochezia (HP:0002573)3.91986573
6B lymphocytopenia (HP:0010976)3.85787928
7Recurrent bacterial skin infections (HP:0005406)3.80842900
8Abnormality of B cell number (HP:0010975)3.80552602
9Colitis (HP:0002583)3.62533593
10Aortic aneurysm (HP:0004942)3.60618153
11Retrobulbar optic neuritis (HP:0100654)3.53372047
12Optic neuritis (HP:0100653)3.53372047
13Glomerulonephritis (HP:0000099)3.52730712
14Agammaglobulinemia (HP:0004432)3.47297279
15Cellulitis (HP:0100658)3.43833818
16Cerebral aneurysm (HP:0004944)3.41234611
17Gastrointestinal infarctions (HP:0005244)3.41203579
18Myositis (HP:0100614)3.34511445
19Spontaneous hematomas (HP:0007420)3.32266115
20Arterial tortuosity (HP:0005116)3.31390561
21Elevated erythrocyte sedimentation rate (HP:0003565)3.29925687
22Inflammation of the large intestine (HP:0002037)3.24123874
23Granulocytopenia (HP:0001913)3.24043264
24Vascular tortuosity (HP:0004948)3.20785070
25Recurrent fungal infections (HP:0002841)3.20324883
26Recurrent viral infections (HP:0004429)3.15166122
27Autoimmune thrombocytopenia (HP:0001973)3.08945185
28Severe combined immunodeficiency (HP:0004430)3.05315537
29Gastrointestinal inflammation (HP:0004386)3.04658639
30Abnormality of macrophages (HP:0004311)3.04245743
31Recurrent bronchitis (HP:0002837)2.92620711
32Chronic otitis media (HP:0000389)2.91310171
33Pustule (HP:0200039)2.90769280
34Aortic dissection (HP:0002647)2.90523957
35IgM deficiency (HP:0002850)2.85409867
36Vacuolated lymphocytes (HP:0001922)2.83167284
37Chronic obstructive pulmonary disease (HP:0006510)2.82619375
38Obstructive lung disease (HP:0006536)2.82619375
39Chest pain (HP:0100749)2.77316439
40Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.75968927
41Recurrent skin infections (HP:0001581)2.74680925
42Dysostosis multiplex (HP:0000943)2.71604569
43Encephalitis (HP:0002383)2.70256394
44Spondylolisthesis (HP:0003302)2.70146645
45Complement deficiency (HP:0004431)2.67452720
46Meningitis (HP:0001287)2.65060596
47Emphysema (HP:0002097)2.64055481
48IgG deficiency (HP:0004315)2.63987255
49Abnormality of glycolipid metabolism (HP:0010969)2.63370547
50Abnormality of liposaccharide metabolism (HP:0010968)2.63370547
51Abnormality of glycosphingolipid metabolism (HP:0004343)2.63370547
52Abnormality of the fingertips (HP:0001211)2.62767290
53Recurrent gram-negative bacterial infections (HP:0005420)2.62645087
54Abnormality of T cell physiology (HP:0011840)2.62328481
55Keratoconjunctivitis sicca (HP:0001097)2.61292093
56Autoimmune hemolytic anemia (HP:0001890)2.59775101
57Hypoplasia of the thymus (HP:0000778)2.57519352
58Abnormality of eosinophils (HP:0001879)2.57356640
59Osteomyelitis (HP:0002754)2.54829937
60Pulmonary infiltrates (HP:0002113)2.54669214
61Chronic diarrhea (HP:0002028)2.53471164
62Mediastinal lymphadenopathy (HP:0100721)2.52661206
63Gastrointestinal stroma tumor (HP:0100723)2.51507878
64Papilledema (HP:0001085)2.50608631
65Nephritis (HP:0000123)2.50029286
66Myocardial infarction (HP:0001658)2.48488813
67Hemoptysis (HP:0002105)2.48365508
68Combined immunodeficiency (HP:0005387)2.47882497
69Abnormality of the nasal mucosa (HP:0000433)2.46890532
70Increased IgE level (HP:0003212)2.46086197
71Fatigue (HP:0012378)2.43848538
72Recurrent cutaneous fungal infections (HP:0011370)2.43391636
73Chronic mucocutaneous candidiasis (HP:0002728)2.43391636
74Vasculitis (HP:0002633)2.43162275
75Stomach cancer (HP:0012126)2.40847230
76Abnormal delayed hypersensitivity skin test (HP:0002963)2.40068031
77Slow saccadic eye movements (HP:0000514)2.39335519
78Panhypogammaglobulinemia (HP:0003139)2.38803813
79Increased cerebral lipofuscin (HP:0011813)2.38279259
80Orchitis (HP:0100796)2.37515876
81Keratoconjunctivitis (HP:0001096)2.37194307
82Mucopolysacchariduria (HP:0008155)2.34778194
83Urinary glycosaminoglycan excretion (HP:0003541)2.34778194
84Interstitial pulmonary disease (HP:0006530)2.30216766
85Abnormality of mucopolysaccharide metabolism (HP:0011020)2.28414817
86Abnormality of polysaccharide metabolism (HP:0011012)2.28414817
87Abnormality of glycosaminoglycan metabolism (HP:0004371)2.28414817
88Verrucae (HP:0200043)2.26972201
89Papilloma (HP:0012740)2.26972201
90Aplasia/Hypoplasia of the thymus (HP:0010515)2.26942365
91Viral hepatitis (HP:0006562)2.26869551
92Urticaria (HP:0001025)2.25640872
93Mitral valve prolapse (HP:0001634)2.21431744
94Increased neuronal autofluorescent lipopigment (HP:0002074)2.18786730
95Prolonged bleeding time (HP:0003010)2.18334411
96Striae distensae (HP:0001065)2.18328784
97Lymphopenia (HP:0001888)2.17065461
98Hypochromic anemia (HP:0001931)2.16648989
99Abnormal platelet function (HP:0011869)2.16603815
100Impaired platelet aggregation (HP:0003540)2.16603815
101Disinhibition (HP:0000734)2.15286725
102Arterial thrombosis (HP:0004420)2.14497589
103Abnormality of complement system (HP:0005339)2.12904603
104Gingivitis (HP:0000230)2.12664845
105Episodic fever (HP:0001954)2.11542351
106Eosinophilia (HP:0001880)2.11206204
107Sepsis (HP:0100806)2.10718132
108Periodontitis (HP:0000704)2.09774952
109Leukocytosis (HP:0001974)2.08308681
110Thrombocytosis (HP:0001894)2.08232255
111Neoplasm of the tracheobronchial system (HP:0100552)2.08165312
112Nonimmune hydrops fetalis (HP:0001790)2.07681626
113Bicuspid aortic valve (HP:0001647)2.07637488
114Axonal loss (HP:0003447)2.07546709
115Hypochromic microcytic anemia (HP:0004840)2.07508491
116Abnormality of cells of the lymphoid lineage (HP:0012140)2.07029114
117Gingival bleeding (HP:0000225)2.06864899
118Nasal polyposis (HP:0100582)2.05997859
119Microcytic anemia (HP:0001935)2.05676560
120Osteolytic defects of the hand bones (HP:0009699)2.05452603
121Osteolytic defects of the phalanges of the hand (HP:0009771)2.05452603
122Abnormality of T cell number (HP:0011839)2.03560866
123Anorexia (HP:0002039)2.02838387
124Subacute progressive viral hepatitis (HP:0006572)2.02125922
125Acute myeloid leukemia (HP:0004808)2.02001398
126Dilatation of the ascending aorta (HP:0005111)2.01723411
127Pulmonary embolism (HP:0002204)2.01220564
128Disproportionate tall stature (HP:0001519)2.00917837
129T lymphocytopenia (HP:0005403)1.99081868
130Epistaxis (HP:0000421)1.98594220
131Facial diplegia (HP:0001349)1.98560445
132Thick nail (HP:0001805)1.98029952
133Polycythemia (HP:0001901)1.98003421
134Thyroiditis (HP:0100646)1.97840997
135Lymphoma (HP:0002665)1.96737533
136Chronic sinusitis (HP:0011109)1.96556610
137Urethral obstruction (HP:0000796)1.95636877
138Alveolar cell carcinoma (HP:0006519)1.95611137
139Abnormality of the peritoneum (HP:0002585)1.94822538
140Skin ulcer (HP:0200042)1.93602899
141Abnormality of T cells (HP:0002843)1.93254283
142Recurrent sinusitis (HP:0011108)1.92593490
143Petechiae (HP:0000967)1.91628967
144Increased IgM level (HP:0003496)1.90954870
145Broad metatarsal (HP:0001783)1.90881706
146Abnormality of the pleura (HP:0002103)1.89635995
147Restrictive lung disease (HP:0002091)1.88343790
148Muscle fiber splitting (HP:0003555)1.86484775
149Cardiomegaly (HP:0001640)1.85321965
150Amyloidosis (HP:0011034)1.83631995
151Abnormality of the thymus (HP:0000777)1.82601184
152Hypergammaglobulinemia (HP:0010702)1.81036819
153Difficulty running (HP:0009046)1.80844595

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TGFBR24.92249358
2MAP4K13.46740581
3ERN12.88688524
4TYK22.86509818
5PRPF4B2.80630257
6KDR2.44124879
7MAP3K102.40562448
8TBK12.33585718
9STK102.25502287
10KIT2.23768919
11JAK12.18151779
12CSF1R2.16360428
13MAP3K142.15055481
14JAK32.07500216
15ZAP701.94790634
16MAP2K31.94742099
17RIPK41.93089256
18IRAK41.86610119
19IKBKE1.84783169
20MAPK151.72259928
21FLT31.69529426
22TIE11.68082407
23RIPK11.55556234
24BTK1.52653470
25CAMK1D1.46968663
26IKBKB1.44380554
27BLK1.41071962
28EPHA31.40917701
29GRK61.40836709
30BMPR21.40011277
31GRK71.38850696
32KSR21.37990080
33TRIB31.37722481
34BRD41.36081594
35TEC1.35751991
36MAP3K11.34795701
37SYK1.32340307
38CSK1.28717461
39HCK1.28539119
40TXK1.28497652
41SIK31.26406465
42FGFR41.25331623
43PKN21.22791015
44IRAK31.22252945
45LRRK21.21329826
46ITK1.17859918
47MAP3K131.15644564
48FGFR31.13896432
49LCK1.12578828
50IRAK21.12323340
51MAP3K21.10286680
52YES11.08902353
53MARK21.08508276
54TRPM71.04750303
55RPS6KA41.03057210
56LYN1.02450773
57JAK21.01873971
58CAMK1G1.00553372
59TTN0.97126119
60EPHB10.96522513
61EEF2K0.94904636
62PDK10.94569633
63CHUK0.93212737
64MAPK120.92906840
65SGK20.92741595
66MAP3K30.90879328
67CLK10.86117276
68MAP2K20.86037743
69PIM10.83500142
70NEK60.82383526
71CDK90.81710869
72SGK30.81407303
73MAPK70.79211530
74TAOK30.78646114
75PTK60.77710773
76MAP3K70.77175528
77RAF10.76234115
78SIK10.73667149
79PDPK10.73404825
80MAP3K90.72301906
81OBSCN0.72114090
82PASK0.71173889
83PIK3CG0.70910601
84NLK0.70700184
85FES0.68495610
86MELK0.68347449
87NME20.67131850
88CDK120.65496131
89STK240.64362113
90TGFBR10.63436712
91MAP3K60.63039002
92STK40.62900651
93ARAF0.62472738
94TNK20.60810209
95MAPKAPK30.58611173
96SIK20.58096370
97INSRR0.56911997
98CDK40.55116918
99MATK0.54673188
100PAK40.53139161
101RET0.51687821
102DMPK0.51620329
103RPS6KC10.48974203
104RPS6KL10.48974203
105MARK30.48727826
106TAOK10.48602162
107MAPKAPK20.46373011
108ABL10.45763811
109NEK90.45223894
110TAOK20.45203586
111DYRK1B0.44752459
112PDGFRB0.43243008
113CDK60.42834319
114IGF1R0.41028425
115MAPK30.40999342
116KSR10.40609922
117MST40.40478390
118PTK2B0.40339584
119RPS6KA60.40231993
120GRK10.39853646
121INSR0.39524670
122CAMK40.38953981
123RPS6KA10.38915693
124HIPK20.38224254
125PRKD10.37987796
126PDGFRA0.36433395
127CDC42BPA0.36255450
128PRKCQ0.36173953
129MAPK40.35754960
130PRKAA20.34851626
131ADRBK20.34630239
132EGFR0.33984705
133IRAK10.33973830
134MOS0.32989479
135PRKD20.32096036
136MAPK110.31697112
137FRK0.31594957

Predicted pathways (KEGG)

RankGene SetZ-score
1B cell receptor signaling pathway_Homo sapiens_hsa046622.72207812
2Staphylococcus aureus infection_Homo sapiens_hsa051502.63649040
3Leishmaniasis_Homo sapiens_hsa051402.59795840
4Osteoclast differentiation_Homo sapiens_hsa043802.57212089
5Primary immunodeficiency_Homo sapiens_hsa053402.31918353
6Glycosaminoglycan degradation_Homo sapiens_hsa005312.26091898
7Other glycan degradation_Homo sapiens_hsa005112.22578340
8NF-kappa B signaling pathway_Homo sapiens_hsa040642.19003645
9Toll-like receptor signaling pathway_Homo sapiens_hsa046202.00084276
10Antigen processing and presentation_Homo sapiens_hsa046121.97104547
11Malaria_Homo sapiens_hsa051441.87673836
12Measles_Homo sapiens_hsa051621.86917217
13Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.86110411
14Intestinal immune network for IgA production_Homo sapiens_hsa046721.82864324
15Toxoplasmosis_Homo sapiens_hsa051451.77470569
16Pertussis_Homo sapiens_hsa051331.74567151
17Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.71711326
18Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.70552703
19Hematopoietic cell lineage_Homo sapiens_hsa046401.66809082
20RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.63392390
21Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.61707600
22Caffeine metabolism_Homo sapiens_hsa002321.59098578
23NOD-like receptor signaling pathway_Homo sapiens_hsa046211.55009041
24Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.54535881
25Asthma_Homo sapiens_hsa053101.53094577
26Graft-versus-host disease_Homo sapiens_hsa053321.53000687
27TNF signaling pathway_Homo sapiens_hsa046681.52332722
28AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.50552250
29Type I diabetes mellitus_Homo sapiens_hsa049401.43598247
30Jak-STAT signaling pathway_Homo sapiens_hsa046301.42772989
31Influenza A_Homo sapiens_hsa051641.42630478
32Leukocyte transendothelial migration_Homo sapiens_hsa046701.42272577
33Tuberculosis_Homo sapiens_hsa051521.39499312
34Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.39295380
35Lysosome_Homo sapiens_hsa041421.38381645
36Legionellosis_Homo sapiens_hsa051341.34105520
37Herpes simplex infection_Homo sapiens_hsa051681.32810723
38T cell receptor signaling pathway_Homo sapiens_hsa046601.32018321
39Renal cell carcinoma_Homo sapiens_hsa052111.31191492
40Dorso-ventral axis formation_Homo sapiens_hsa043201.28912311
41Chemokine signaling pathway_Homo sapiens_hsa040621.28146452
42Platelet activation_Homo sapiens_hsa046111.24545960
43Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.24514221
44Chronic myeloid leukemia_Homo sapiens_hsa052201.22560151
45Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.22410619
46Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.21265046
47Apoptosis_Homo sapiens_hsa042101.21078563
48Hepatitis B_Homo sapiens_hsa051611.16411105
49Pancreatic cancer_Homo sapiens_hsa052121.14883146
50Transcriptional misregulation in cancer_Homo sapiens_hsa052021.12489100
51Allograft rejection_Homo sapiens_hsa053301.08935835
52African trypanosomiasis_Homo sapiens_hsa051431.08771504
53Acute myeloid leukemia_Homo sapiens_hsa052211.08466759
54Circadian rhythm_Homo sapiens_hsa047101.06570394
55Shigellosis_Homo sapiens_hsa051311.06033100
56Endometrial cancer_Homo sapiens_hsa052131.04276961
57Phosphatidylinositol signaling system_Homo sapiens_hsa040701.03602432
58mTOR signaling pathway_Homo sapiens_hsa041501.01054709
59Thyroid cancer_Homo sapiens_hsa052160.98319639
60Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.96331471
61Inositol phosphate metabolism_Homo sapiens_hsa005620.94546217
62Hepatitis C_Homo sapiens_hsa051600.94195178
63Small cell lung cancer_Homo sapiens_hsa052220.93855519
64Salmonella infection_Homo sapiens_hsa051320.93606459
65Complement and coagulation cascades_Homo sapiens_hsa046100.92625869
66Focal adhesion_Homo sapiens_hsa045100.89879167
67Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.88185232
68Adherens junction_Homo sapiens_hsa045200.86827488
69Insulin resistance_Homo sapiens_hsa049310.84842026
70Viral myocarditis_Homo sapiens_hsa054160.83075521
71Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.77927624
72ErbB signaling pathway_Homo sapiens_hsa040120.77606123
73Amoebiasis_Homo sapiens_hsa051460.77579173
74Neurotrophin signaling pathway_Homo sapiens_hsa047220.75112622
75Rheumatoid arthritis_Homo sapiens_hsa053230.72932495
76Adipocytokine signaling pathway_Homo sapiens_hsa049200.71998376
77Sphingolipid signaling pathway_Homo sapiens_hsa040710.71636120
78FoxO signaling pathway_Homo sapiens_hsa040680.70236987
79Proteoglycans in cancer_Homo sapiens_hsa052050.68565843
80Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.67983473
81HTLV-I infection_Homo sapiens_hsa051660.67540797
82GnRH signaling pathway_Homo sapiens_hsa049120.67399539
83Prolactin signaling pathway_Homo sapiens_hsa049170.67268254
84Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66528005
85ECM-receptor interaction_Homo sapiens_hsa045120.66060710
86Type II diabetes mellitus_Homo sapiens_hsa049300.64655193
87Notch signaling pathway_Homo sapiens_hsa043300.64447096
88Insulin signaling pathway_Homo sapiens_hsa049100.64052117
89VEGF signaling pathway_Homo sapiens_hsa043700.63303739
90Rap1 signaling pathway_Homo sapiens_hsa040150.58328683
91SNARE interactions in vesicular transport_Homo sapiens_hsa041300.57676626
92Regulation of actin cytoskeleton_Homo sapiens_hsa048100.57661474
93Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.56074779
94ABC transporters_Homo sapiens_hsa020100.55413858
95Viral carcinogenesis_Homo sapiens_hsa052030.55379117
96Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.53921158
97Prostate cancer_Homo sapiens_hsa052150.53686950
98Non-small cell lung cancer_Homo sapiens_hsa052230.53141419
99Thyroid hormone signaling pathway_Homo sapiens_hsa049190.51252691
100Colorectal cancer_Homo sapiens_hsa052100.50549188
101Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.50547175
102Regulation of autophagy_Homo sapiens_hsa041400.50331575
103Endocytosis_Homo sapiens_hsa041440.50303868
104Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.48852290
105Glycerophospholipid metabolism_Homo sapiens_hsa005640.48069379
106Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.47624614
107Pathways in cancer_Homo sapiens_hsa052000.46607428
108Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.45568145
109Ovarian steroidogenesis_Homo sapiens_hsa049130.45420334
110MAPK signaling pathway_Homo sapiens_hsa040100.43145823
111Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.43119269
112Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.42968179
113Autoimmune thyroid disease_Homo sapiens_hsa053200.41643582
114MicroRNAs in cancer_Homo sapiens_hsa052060.41088946
115HIF-1 signaling pathway_Homo sapiens_hsa040660.40372428
116Lysine degradation_Homo sapiens_hsa003100.39873688
117PI3K-Akt signaling pathway_Homo sapiens_hsa041510.38722643
118Systemic lupus erythematosus_Homo sapiens_hsa053220.37440012
119Phospholipase D signaling pathway_Homo sapiens_hsa040720.37307089
120Choline metabolism in cancer_Homo sapiens_hsa052310.36555759
121Epstein-Barr virus infection_Homo sapiens_hsa051690.36529543
122Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.35313565
123Longevity regulating pathway - mammal_Homo sapiens_hsa042110.34867127
124Phagosome_Homo sapiens_hsa041450.34370763
125Prion diseases_Homo sapiens_hsa050200.33508252
126Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.33197792

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