MYL4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Myosin is a hexameric ATPase cellular motor protein. It is composed of two myosin heavy chains, two nonphosphorylatable myosin alkali light chains, and two phosphorylatable myosin regulatory light chains. This gene encodes a myosin alkali light chain that is found in embryonic muscle and adult atria. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cardiac myofibril assembly (GO:0055003)9.76531556
2sarcomere organization (GO:0045214)9.02705491
3* actin-mediated cell contraction (GO:0070252)8.53693315
4myofibril assembly (GO:0030239)8.18760450
5cardiac muscle tissue morphogenesis (GO:0055008)7.56879829
6cardiac muscle hypertrophy (GO:0003300)7.23484838
7regulation of cardioblast differentiation (GO:0051890)7.02263662
8striated muscle hypertrophy (GO:0014897)6.80564714
9muscle tissue morphogenesis (GO:0060415)6.79686101
10cardiac muscle cell development (GO:0055013)6.72315379
11heart contraction (GO:0060047)6.72020288
12heart process (GO:0003015)6.72020288
13* cardiac muscle contraction (GO:0060048)6.63819348
14ventricular cardiac muscle tissue morphogenesis (GO:0055010)6.55413457
15negative regulation of cardiac muscle cell apoptotic process (GO:0010667)6.51851902
16actomyosin structure organization (GO:0031032)6.50327124
17negative regulation of potassium ion transmembrane transporter activity (GO:1901017)6.47097462
18regulation of sarcomere organization (GO:0060297)6.43570972
19cardiac cell development (GO:0055006)6.34921909
20* actin filament-based movement (GO:0030048)6.32526219
21muscle hypertrophy (GO:0014896)6.06227806
22adult heart development (GO:0007512)5.80612066
23regulation of relaxation of muscle (GO:1901077)5.76250017
24* striated muscle contraction (GO:0006941)5.73702295
25negative regulation of potassium ion transmembrane transport (GO:1901380)5.67485806
26negative regulation of striated muscle cell apoptotic process (GO:0010664)5.64406511
27cardiac chamber formation (GO:0003207)5.45752305
28atrial septum morphogenesis (GO:0060413)5.39352173
29mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.38881181
30positive regulation of cardiac muscle cell proliferation (GO:0060045)5.17432995
31muscle hypertrophy in response to stress (GO:0003299)5.09858123
32cardiac muscle adaptation (GO:0014887)5.09858123
33cardiac muscle hypertrophy in response to stress (GO:0014898)5.09858123
34heart trabecula formation (GO:0060347)5.02390421
35regulation of cardiac muscle cell contraction (GO:0086004)4.96444424
36negative regulation of myotube differentiation (GO:0010832)4.93666035
37energy coupled proton transport, down electrochemical gradient (GO:0015985)4.92712877
38ATP synthesis coupled proton transport (GO:0015986)4.92712877
39response to inactivity (GO:0014854)4.87523955
40positive regulation of cardiac muscle tissue development (GO:0055025)4.87235293
41regulation of skeletal muscle contraction (GO:0014819)4.86209606
42positive regulation of cardiac muscle tissue growth (GO:0055023)4.84918508
43regulation of heart rate (GO:0002027)4.83491222
44cardiac right ventricle morphogenesis (GO:0003215)4.60620114
45ventricular cardiac muscle cell development (GO:0055015)4.58866198
46response to stimulus involved in regulation of muscle adaptation (GO:0014874)4.54322030
47regulation of striated muscle contraction (GO:0006942)4.49865022
48outflow tract septum morphogenesis (GO:0003148)4.46256559
49regulation of actin filament-based movement (GO:1903115)4.44189950
50endocardial cushion development (GO:0003197)4.43841327
51cell communication involved in cardiac conduction (GO:0086065)4.42734901
52striated muscle cell development (GO:0055002)4.35584309
53regulation of secondary heart field cardioblast proliferation (GO:0003266)4.29230514
54regulation of cardioblast proliferation (GO:0003264)4.29230514
55regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)4.29174359
56oxidative phosphorylation (GO:0006119)4.28394848
57regulation of cardiac muscle contraction (GO:0055117)4.28056661
58plasma membrane repair (GO:0001778)4.25311974
59positive regulation of heart growth (GO:0060421)4.25030617
60regulation of striated muscle cell apoptotic process (GO:0010662)4.22098248
61tricarboxylic acid cycle (GO:0006099)4.21620858
62* regulation of heart contraction (GO:0008016)4.20498003
63regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)4.17147816
64atrioventricular valve morphogenesis (GO:0003181)4.16383051
65cell migration involved in heart development (GO:0060973)4.15974108
66negative regulation of protein localization to cell surface (GO:2000009)4.15440168
67relaxation of cardiac muscle (GO:0055119)4.05065260
68positive regulation of myotube differentiation (GO:0010831)4.02389019
69positive regulation of myoblast differentiation (GO:0045663)3.99835488
70ventricular cardiac muscle cell action potential (GO:0086005)3.98997160
71cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.97017459
72regulation of cardiac muscle cell proliferation (GO:0060043)3.96235769
73regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.95778430
74muscle cell fate commitment (GO:0042693)3.94547071
75* regulation of the force of heart contraction (GO:0002026)3.93844103
76bundle of His cell to Purkinje myocyte communication (GO:0086069)3.93674925
77skeletal muscle contraction (GO:0003009)3.93030788
78regulation of cardiac muscle cell apoptotic process (GO:0010665)3.92365968
79regulation of membrane repolarization (GO:0060306)3.91257376
80cardiac ventricle formation (GO:0003211)3.88467496
81positive regulation of muscle tissue development (GO:1901863)3.86264713
82striated muscle adaptation (GO:0014888)3.84576123
83regulation of cardiac muscle tissue growth (GO:0055021)3.82055500
84muscle cell development (GO:0055001)3.79772313
85positive regulation of muscle organ development (GO:0048636)3.79673971
86positive regulation of striated muscle tissue development (GO:0045844)3.79673971
87muscle fiber development (GO:0048747)3.74073875
88heart valve formation (GO:0003188)3.71749861
89regulation of cardiac muscle tissue development (GO:0055024)3.70583283
90relaxation of smooth muscle (GO:0044557)3.65709077
91cardiac conduction (GO:0061337)3.64534895
92negative regulation of striated muscle cell differentiation (GO:0051154)3.62733328
93cardiac muscle cell action potential (GO:0086001)3.57525560
94epithelial cell-cell adhesion (GO:0090136)3.56492757
95regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.56477737
96positive regulation of striated muscle cell differentiation (GO:0051155)3.55863459
97sarcoplasmic reticulum calcium ion transport (GO:0070296)3.55339436
98positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.54881774
99positive regulation of cardiac muscle cell differentiation (GO:2000727)3.51524144
100regulation of muscle contraction (GO:0006937)3.48488912
101positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.48442698
102respiratory electron transport chain (GO:0022904)3.48083996
103cardiac muscle tissue development (GO:0048738)3.45655398
104regulation of muscle system process (GO:0090257)3.44738976
105regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.44656437
106cardiac muscle cell action potential involved in contraction (GO:0086002)3.40988662
107electron transport chain (GO:0022900)3.40448506
108cell communication by electrical coupling (GO:0010644)3.38844840
109* muscle contraction (GO:0006936)3.38683029
110muscle cell cellular homeostasis (GO:0046716)3.38644061
111muscle adaptation (GO:0043500)3.38617914
112regulation of transforming growth factor beta2 production (GO:0032909)3.38263766
113embryonic heart tube development (GO:0035050)3.37760903
114trabecula formation (GO:0060343)3.37211018
115cardiac septum development (GO:0003279)3.35924150
116regulation of heart growth (GO:0060420)3.35006895
117negative regulation of potassium ion transport (GO:0043267)3.34032916
118* regulation of ATPase activity (GO:0043462)3.34021959
119* regulation of ATP catabolic process (GO:1903289)3.34021959
120* muscle system process (GO:0003012)3.26151991
121regulation of cardiac muscle cell differentiation (GO:2000725)3.25880483
122* muscle filament sliding (GO:0030049)10.0861386
123* actin-myosin filament sliding (GO:0033275)10.0861386

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EP300_21415370_ChIP-Seq_HL-1_Mouse7.13885943
2RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.96611632
3MEF2A_21415370_ChIP-Seq_HL-1_Mouse4.88947990
4CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human4.69778577
5ESR1_20079471_ChIP-ChIP_T-47D_Human4.49317553
6ESRRB_18555785_ChIP-Seq_MESCs_Mouse4.40547583
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.98820534
8BP1_19119308_ChIP-ChIP_Hs578T_Human3.87426585
9TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.54650760
10GATA4_21415370_ChIP-Seq_HL-1_Mouse3.50660154
11* TBX20_22080862_ChIP-Seq_HEART_Mouse3.38118039
12* TBX20_22328084_ChIP-Seq_HEART_Mouse3.38118039
13* GATA1_19941826_ChIP-Seq_K562_Human3.37808280
14* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse3.28128426
15EZH2_22144423_ChIP-Seq_EOC_Human3.11903782
16ISL1_27105846_Chip-Seq_CPCs_Mouse3.00356109
17PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.77421182
18WT1_19549856_ChIP-ChIP_CCG9911_Human2.66659763
19HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.56600771
20NKX2-5_21415370_ChIP-Seq_HL-1_Mouse2.36704243
21* TRIM28_21343339_ChIP-Seq_HEK293_Human2.32460174
22GATA1_22025678_ChIP-Seq_K562_Human2.22392943
23TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.22162487
24CDX2_19796622_ChIP-Seq_MESCs_Mouse2.14850264
25* GATA2_19941826_ChIP-Seq_K562_Human2.12629858
26EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.09918575
27RBPJ_22232070_ChIP-Seq_NCS_Mouse2.07697114
28* HIF1A_21447827_ChIP-Seq_MCF-7_Human2.04581370
29* SRF_21415370_ChIP-Seq_HL-1_Mouse1.98274086
30ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.97982572
31TP63_17297297_ChIP-ChIP_HaCaT_Human1.92374546
32SALL4_18804426_ChIP-ChIP_XEN_Mouse1.88039655
33RARG_19884340_ChIP-ChIP_MEFs_Mouse1.86674483
34KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.84612054
35TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67054906
36GATA1_19941827_ChIP-Seq_MEL_Mouse1.61037474
37TP63_19390658_ChIP-ChIP_HaCaT_Human1.56473279
38ZNF274_21170338_ChIP-Seq_K562_Hela1.56354942
39TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.51022383
40PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.50327392
41ZNF263_19887448_ChIP-Seq_K562_Human1.48797051
42STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.43042322
43CREB1_15753290_ChIP-ChIP_HEK293T_Human1.34257080
44THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.31851256
45NFIB_24661679_ChIP-Seq_LUNG_Mouse1.31320171
46CLOCK_20551151_ChIP-Seq_293T_Human1.30746614
47LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.29584410
48NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.26669384
49GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24501308
50SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.24359715
51* GATA1_19941827_ChIP-Seq_MEL86_Mouse1.16286426
52KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.16109262
53BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.15036991
54SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.13493090
55GATA2_21666600_ChIP-Seq_HMVEC_Human1.12079466
56ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.11345396
57DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.10568737
58* CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.10372753
59NELFA_20434984_ChIP-Seq_ESCs_Mouse1.10288087
60SMAD4_21741376_ChIP-Seq_HESCs_Human1.08837522
61SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.07713540
62EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.07201507
63TBX5_21415370_ChIP-Seq_HL-1_Mouse1.06390345
64GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.06027537
65ZFP281_18757296_ChIP-ChIP_E14_Mouse1.05660186
66CTCF_27219007_Chip-Seq_Bcells_Human1.05285212
67PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.04405854
68NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.04400436
69DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.04352741
70YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.03875963
71SOX9_24532713_ChIP-Seq_HFSC_Mouse1.02972033
72ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.02518021
73KDM2B_26808549_Chip-Seq_DND41_Human1.01488962
74KDM2B_26808549_Chip-Seq_K562_Human1.01452646
75HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.99881494
76CJUN_26792858_Chip-Seq_BT549_Human0.98878375
77RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.96895826
78TP53_23651856_ChIP-Seq_MEFs_Mouse0.94731440
79LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94623615
80CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.94543499
81TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.93698006
82TBL1_22424771_ChIP-Seq_293T_Human0.93406586
83RNF2_18974828_ChIP-Seq_MESCs_Mouse0.93396696
84EZH2_18974828_ChIP-Seq_MESCs_Mouse0.93396696
85* EZH2_27294783_Chip-Seq_ESCs_Mouse0.93041670
86NANOG_16153702_ChIP-ChIP_HESCs_Human0.91299711
87BCAT_22108803_ChIP-Seq_LS180_Human0.90233816
88MYC_18555785_ChIP-Seq_MESCs_Mouse0.89726836
89LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.89384105
90NCOR1_26117541_ChIP-Seq_K562_Human0.89177266
91SOX9_26525672_Chip-Seq_HEART_Mouse0.89156996
92TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.87675995
93CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.87256898
94JARID2_20064375_ChIP-Seq_MESCs_Mouse0.87237545
95PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.86050188
96SPI1_23127762_ChIP-Seq_K562_Human0.84909822
97SOX17_20123909_ChIP-Seq_XEN_Mouse0.84857332
98* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.84368101
99MYC_19030024_ChIP-ChIP_MESCs_Mouse0.83984806
100TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83923506
101KDM2B_26808549_Chip-Seq_SUP-B15_Human0.83571124
102* EOMES_21245162_ChIP-Seq_HESCs_Human0.83043402
103TP53_16413492_ChIP-PET_HCT116_Human0.82899978
104ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.82675445
105PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.80415617
106ELK1_19687146_ChIP-ChIP_HELA_Human0.80362689
107* GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.80217684
108EST1_17652178_ChIP-ChIP_JURKAT_Human0.80159023
109HTT_18923047_ChIP-ChIP_STHdh_Human0.79906984
110ELK3_25401928_ChIP-Seq_HUVEC_Human0.79821843
111CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.79510099
112TCF7_22412390_ChIP-Seq_EML_Mouse0.79438058
113RNF2_27304074_Chip-Seq_ESCs_Mouse0.78798588
114MYC_19829295_ChIP-Seq_ESCs_Human0.77710682
115THAP11_20581084_ChIP-Seq_MESCs_Mouse0.76935165
116MTF2_20144788_ChIP-Seq_MESCs_Mouse0.76269027
117SCL_19346495_ChIP-Seq_HPC-7_Human0.75865960
118SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.75773405
119MYC_27129775_Chip-Seq_CORNEA_Mouse0.75562593
120SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.74779110
121SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.74721731
122PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.73387558
123NFI_21473784_ChIP-Seq_ESCs_Mouse0.72278548
124EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.70885527
125HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.70738487
126EZH2_27304074_Chip-Seq_ESCs_Mouse0.70442702
127RACK7_27058665_Chip-Seq_MCF-7_Human0.69844050
128NFYA_21822215_ChIP-Seq_K562_Human0.69359395
129FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.68548950
130SOX3_22085726_ChIP-Seq_NPCs_Mouse0.68067311
131* KLF5_20875108_ChIP-Seq_MESCs_Mouse0.67677508
132SPI1_20517297_ChIP-Seq_HL60_Human0.67140969
133HNFA_21074721_ChIP-Seq_CACO-2_Human0.66780730
134SOX2_18555785_ChIP-Seq_MESCs_Mouse0.66763510
135NR3C1_23031785_ChIP-Seq_PC12_Mouse0.65711222
136NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.64947065
137NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.64735792
138GF1_26923725_Chip-Seq_HPCs_Mouse0.64598105
139FUS_26573619_Chip-Seq_HEK293_Human0.64545476
140WT1_25993318_ChIP-Seq_PODOCYTE_Human0.64345425
141TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.63393133
142WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.63109615
143* NANOG_21062744_ChIP-ChIP_HESCs_Human0.63107225
144BRD4_25478319_ChIP-Seq_HGPS_Human0.61799606
145SMAD3_21741376_ChIP-Seq_HESCs_Human0.61792194
146* CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.61335054
147GF1B_26923725_Chip-Seq_HPCs_Mouse0.61245547
148ESR1_21235772_ChIP-Seq_MCF-7_Human0.60692810
149PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.59321398
150AUTS2_25519132_ChIP-Seq_293T-REX_Human0.59236583
151SMC3_22415368_ChIP-Seq_MEFs_Mouse0.58904267
152PPAR_26484153_Chip-Seq_NCI-H1993_Human0.57540292
153ELK1_22589737_ChIP-Seq_MCF10A_Human0.57328424

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004084_abnormal_cardiac_muscle6.35235366
2MP0000749_muscle_degeneration5.41897519
3MP0004036_abnormal_muscle_relaxation4.35347494
4MP0005330_cardiomyopathy3.83623506
5MP0002972_abnormal_cardiac_muscle3.65202636
6MP0002837_dystrophic_cardiac_calcinosis3.59764317
7MP0000751_myopathy3.48874601
8MP0004215_abnormal_myocardial_fiber3.47830847
9MP0008775_abnormal_heart_ventricle3.23350764
10MP0004087_abnormal_muscle_fiber3.14464369
11MP0004510_myositis3.04609857
12MP0010630_abnormal_cardiac_muscle2.91128714
13MP0003122_maternal_imprinting2.87598735
14MP0005620_abnormal_muscle_contractility2.87554971
15MP0004145_abnormal_muscle_electrophysio2.77097704
16MP0003137_abnormal_impulse_conducting2.66208923
17MP0003828_pulmonary_edema2.62382188
18MP0003221_abnormal_cardiomyocyte_apopto2.51374734
19MP0002106_abnormal_muscle_physiology2.51009415
20MP0005385_cardiovascular_system_phenoty2.50877873
21MP0001544_abnormal_cardiovascular_syste2.50877873
22MP0006138_congestive_heart_failure2.50611680
23MP0003950_abnormal_plasma_membrane2.47255434
24MP0002127_abnormal_cardiovascular_syste2.44789521
25MP0003567_abnormal_fetal_cardiomyocyte2.43899100
26MP0004085_abnormal_heartbeat2.41545762
27MP0005451_abnormal_body_composition2.33308732
28MP0002269_muscular_atrophy2.29709632
29MP0000750_abnormal_muscle_regeneration2.19240769
30MP0000747_muscle_weakness2.10977464
31MP0005369_muscle_phenotype2.02541743
32MP0003123_paternal_imprinting1.96346140
33MP0004147_increased_porphyrin_level1.86018676
34MP0000759_abnormal_skeletal_muscle1.84525105
35MP0004484_altered_response_of1.84335147
36MP0003646_muscle_fatigue1.83333819
37MP0004233_abnormal_muscle_weight1.80244081
38MP0003121_genomic_imprinting1.77817838
39MP0003941_abnormal_skin_development1.53221151
40MP0004272_abnormal_basement_membrane1.42449209
41MP0000733_abnormal_muscle_development1.40427831
42MP0009384_cardiac_valve_regurgitation1.39159366
43MP0000266_abnormal_heart_morphology1.34085872
44MP0003566_abnormal_cell_adhesion1.23223159
45MP0006036_abnormal_mitochondrial_physio1.22732779
46MP0008438_abnormal_cutaneous_collagen1.22237809
47MP0003385_abnormal_body_wall1.09214822
48MP0009697_abnormal_copulation1.04877278
49MP0002088_abnormal_embryonic_growth/wei1.03857267
50MP0003984_embryonic_growth_retardation1.01916175
51MP0003279_aneurysm1.00545006
52MP0005503_abnormal_tendon_morphology0.97844292
53MP0003115_abnormal_respiratory_system0.94834609
54MP0005623_abnormal_meninges_morphology0.94680565
55MP0002102_abnormal_ear_morphology0.92843841
56MP0001730_embryonic_growth_arrest0.91938585
57MP0002925_abnormal_cardiovascular_devel0.90066416
58MP0002128_abnormal_blood_circulation0.88164712
59MP0000767_abnormal_smooth_muscle0.84804496
60MP0002332_abnormal_exercise_endurance0.84184438
61MP0005165_increased_susceptibility_to0.81569799
62MP0001661_extended_life_span0.80161814
63MP0001784_abnormal_fluid_regulation0.79739381
64MP0000516_abnormal_urinary_system0.79444010
65MP0005367_renal/urinary_system_phenotyp0.79444010
66MP0000537_abnormal_urethra_morphology0.78511812
67MP0003806_abnormal_nucleotide_metabolis0.73320053
68MP0002108_abnormal_muscle_morphology0.73232277
69MP0005380_embryogenesis_phenotype0.73021868
70MP0001672_abnormal_embryogenesis/_devel0.73021868
71MP0006035_abnormal_mitochondrial_morpho0.71916008
72MP0008004_abnormal_stomach_pH0.69905418
73MP0005275_abnormal_skin_tensile0.69448212
74MP0004130_abnormal_muscle_cell0.68446478
75MP0002234_abnormal_pharynx_morphology0.67420391
76MP0002249_abnormal_larynx_morphology0.66742273
77MP0000230_abnormal_systemic_arterial0.64806609
78MP0010368_abnormal_lymphatic_system0.64419527
79MP0003656_abnormal_erythrocyte_physiolo0.59251724
80MP0003705_abnormal_hypodermis_morpholog0.59123448
81MP0002086_abnormal_extraembryonic_tissu0.58829691
82MP0001614_abnormal_blood_vessel0.58614960
83MP0000762_abnormal_tongue_morphology0.57550835
84MP0005248_abnormal_Harderian_gland0.56531997
85MP0001697_abnormal_embryo_size0.56233359
86MP0000462_abnormal_digestive_system0.53766129
87MP0005266_abnormal_metabolism0.52652210
88MP0003942_abnormal_urinary_system0.52650415
89MP0004197_abnormal_fetal_growth/weight/0.52454823
90MP0009250_abnormal_appendicular_skeleto0.52424152
91MP0010030_abnormal_orbit_morphology0.50774917
92MP0009672_abnormal_birth_weight0.49551436
93MP0001958_emphysema0.47672701
94MP0003948_abnormal_gas_homeostasis0.47634990
95MP0004270_analgesia0.47583439
96MP0001175_abnormal_lung_morphology0.47416822
97MP0003315_abnormal_perineum_morphology0.46382025
98MP0001879_abnormal_lymphatic_vessel0.44270888
99MP0002132_abnormal_respiratory_system0.44239885
100MP0005388_respiratory_system_phenotype0.43964207
101MP0002133_abnormal_respiratory_system0.43964207
102MP0005595_abnormal_vascular_smooth0.43632970
103MP0002933_joint_inflammation0.42506727
104MP0008007_abnormal_cellular_replicative0.40952052
105MP0000343_altered_response_to0.40917024
106MP0003935_abnormal_craniofacial_develop0.40390747
107MP0001299_abnormal_eye_distance/0.38651513
108MP0002080_prenatal_lethality0.38456751
109MP0003119_abnormal_digestive_system0.38299588
110MP0003937_abnormal_limbs/digits/tail_de0.38215895
111MP0000428_abnormal_craniofacial_morphol0.38211964
112MP0005187_abnormal_penis_morphology0.37785851
113MP0006054_spinal_hemorrhage0.36501725
114MP0005377_hearing/vestibular/ear_phenot0.36312374
115MP0005083_abnormal_biliary_tract0.28507087
116MP0002822_catalepsy0.25906892
117MP0008874_decreased_physiological_sensi0.24871739
118MP0003045_fibrosis0.24240125
119MP0004264_abnormal_extraembryonic_tissu0.23572343
120MP0000534_abnormal_ureter_morphology0.23451724
121MP0005584_abnormal_enzyme/coenzyme_acti0.22336781

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)7.24049162
2Exercise-induced muscle cramps (HP:0003710)6.72303204
3Calf muscle hypertrophy (HP:0008981)6.70375777
4Muscle hypertrophy of the lower extremities (HP:0008968)5.94451777
5Exercise-induced myalgia (HP:0003738)5.55746135
6Abnormality of the calf musculature (HP:0001430)5.48692561
7Abnormality of the left ventricular outflow tract (HP:0011103)5.28732879
8Subaortic stenosis (HP:0001682)5.28732879
9Ventricular tachycardia (HP:0004756)5.24587741
10Atrial fibrillation (HP:0005110)5.18871674
11Lipoatrophy (HP:0100578)5.01164070
12Primary atrial arrhythmia (HP:0001692)4.82067972
13Aplasia of the musculature (HP:0100854)4.75470754
14Supraventricular tachycardia (HP:0004755)4.68410382
15Supraventricular arrhythmia (HP:0005115)4.57484546
16EMG: myopathic abnormalities (HP:0003458)4.47192513
17Centrally nucleated skeletal muscle fibers (HP:0003687)4.46544769
18Hyporeflexia of lower limbs (HP:0002600)4.43012207
19Type 1 muscle fiber predominance (HP:0003803)4.41286482
20Hypoplastic heart (HP:0001961)4.35992904
21Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)4.09054228
22Right ventricular cardiomyopathy (HP:0011663)4.06231676
23Muscle fiber splitting (HP:0003555)4.04848462
24Dilated cardiomyopathy (HP:0001644)3.84799607
25Nemaline bodies (HP:0003798)3.74933366
26Muscle fiber inclusion bodies (HP:0100299)3.71920925
27Myoglobinuria (HP:0002913)3.67570870
28Ventricular arrhythmia (HP:0004308)3.67117006
29Congenital malformation of the right heart (HP:0011723)3.63987883
30Double outlet right ventricle (HP:0001719)3.63987883
31Prolonged QT interval (HP:0001657)3.55992862
32Hypoplastic left heart (HP:0004383)3.50483193
33Syncope (HP:0001279)3.49825550
34Patent foramen ovale (HP:0001655)3.34461726
35Neck muscle weakness (HP:0000467)3.29903494
36Distal arthrogryposis (HP:0005684)3.24459515
37Palpitations (HP:0001962)3.12609576
38Rhabdomyolysis (HP:0003201)3.12389861
39Bradycardia (HP:0001662)3.12330319
40Generalized muscle weakness (HP:0003324)3.11768521
41Round ear (HP:0100830)3.11058756
42Aplasia/Hypoplasia involving the musculature (HP:0001460)3.03269456
43Ragged-red muscle fibers (HP:0003200)2.97724849
44Asymmetric septal hypertrophy (HP:0001670)2.95017530
45Fetal akinesia sequence (HP:0001989)2.92587769
46Popliteal pterygium (HP:0009756)2.81179239
47Abnormality of glycolysis (HP:0004366)2.68068304
48Increased serum pyruvate (HP:0003542)2.68068304
49Left ventricular hypertrophy (HP:0001712)2.68031516
50Mildly elevated creatine phosphokinase (HP:0008180)2.66542919
51Acute necrotizing encephalopathy (HP:0006965)2.60906068
52Thin ribs (HP:0000883)2.57380388
53Amniotic constriction ring (HP:0009775)2.55974463
54Abnormality of placental membranes (HP:0011409)2.55974463
55Diaphragmatic weakness (HP:0009113)2.54565070
56Abnormal EKG (HP:0003115)2.51545295
57Ulnar deviation of the wrist (HP:0003049)2.50811723
58Truncus arteriosus (HP:0001660)2.50622176
59Malignant hyperthermia (HP:0002047)2.49434541
60Distal lower limb muscle weakness (HP:0009053)2.49307580
61Conjunctival hamartoma (HP:0100780)2.48062206
62Abnormal mitochondria in muscle tissue (HP:0008316)2.48016297
63Rimmed vacuoles (HP:0003805)2.47385912
64Atrioventricular block (HP:0001678)2.46237901
65Palmoplantar keratoderma (HP:0000982)2.42843163
66Hip contracture (HP:0003273)2.40454789
67EMG: neuropathic changes (HP:0003445)2.39127430
68Gowers sign (HP:0003391)2.38195913
69Exercise intolerance (HP:0003546)2.37518699
70Heart block (HP:0012722)2.37143990
71Easy fatigability (HP:0003388)2.35351906
72Weak cry (HP:0001612)2.33281467
73Neoplasm of the adrenal gland (HP:0100631)2.32051336
74Pulmonary artery stenosis (HP:0004415)2.31581592
75Ventricular fibrillation (HP:0001663)2.29181936
76Difficulty running (HP:0009046)2.28226404
77Pheochromocytoma (HP:0002666)2.26321779
78Type 2 muscle fiber atrophy (HP:0003554)2.23753017
79Abnormal atrioventricular conduction (HP:0005150)2.21509916
80Abnormality of the foot musculature (HP:0001436)2.15904992
81Steppage gait (HP:0003376)2.13978292
82Limited hip movement (HP:0008800)2.13006510
83Abnormal ventriculo-arterial connection (HP:0011563)2.10835697
84Transposition of the great arteries (HP:0001669)2.10835697
85Abnormal connection of the cardiac segments (HP:0011545)2.10835697
86Deformed tarsal bones (HP:0008119)2.08507667
87Progressive macrocephaly (HP:0004481)2.07783996
88Neuroendocrine neoplasm (HP:0100634)2.06280523
89Mitochondrial inheritance (HP:0001427)2.06254303
90Increased CSF lactate (HP:0002490)2.05991627
91Myotonia (HP:0002486)2.05156213
92Abnormality of the heme biosynthetic pathway (HP:0010472)2.05084119
93Bundle branch block (HP:0011710)2.05045267
94Periauricular skin pits (HP:0100277)2.04852764
95Preauricular pit (HP:0004467)2.04852764
96Hepatic necrosis (HP:0002605)2.02914865
97Difficulty climbing stairs (HP:0003551)2.01919677
98Increased variability in muscle fiber diameter (HP:0003557)2.00976422
99Acute encephalopathy (HP:0006846)1.99491352
100Fatigable weakness (HP:0003473)1.98785330
101Abnormality of the neuromuscular junction (HP:0003398)1.98785330
102Areflexia of lower limbs (HP:0002522)1.98275350
103Increased connective tissue (HP:0009025)1.97968799
104Calcaneovalgus deformity (HP:0001848)1.96462911
105Sudden cardiac death (HP:0001645)1.95121755
106Muscle fiber atrophy (HP:0100295)1.94955464
107Metaphyseal cupping (HP:0003021)1.94825111
108Abnormal gallbladder physiology (HP:0012438)1.93806492
109Cholecystitis (HP:0001082)1.93806492
110Abnormality of the tricuspid valve (HP:0001702)1.91433162
111Skin pits (HP:0100276)1.84382280
112Absent phalangeal crease (HP:0006109)1.82594318
113Congestive heart failure (HP:0001635)1.80451575
114Scapular winging (HP:0003691)1.79677906
115Pterygium (HP:0001059)1.79424118
116Hepatoblastoma (HP:0002884)1.79044669
117Abnormality of skeletal muscle fiber size (HP:0012084)1.77316043
118Bulbar palsy (HP:0001283)1.71380068
119Abnormality of the calcaneus (HP:0008364)1.71238007
120Partial duplication of thumb phalanx (HP:0009944)1.71187514
121Hypoplastic ischia (HP:0003175)1.70992382

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OBSCN9.76972931
2MYLK5.45989873
3STK244.19091434
4ZAK3.44310771
5PKN23.16205158
6PIK3CA2.86022803
7GRK72.78505585
8STK38L2.68072585
9MUSK2.35965660
10LIMK12.29368335
11MAPKAPK32.17769489
12DMPK1.96028618
13ILK1.94116161
14CDC42BPA1.91544847
15DDR21.80982633
16TESK11.63860217
17DAPK31.62448773
18MOS1.59551726
19TTN1.55647747
20TRIB31.41655754
21MAP3K101.39477918
22KSR21.26121570
23TRPM71.24875957
24FLT31.19999708
25NEK11.19261628
26PIK3CG1.11428055
27PDK31.08703645
28PDK41.08703645
29MAP3K51.08562501
30ROCK11.07425389
31CAMK41.05050146
32PTK2B1.03250937
33PRKD30.97972318
34PHKG20.97405393
35PHKG10.97405393
36PAK30.95472472
37STK40.94370455
38STK30.91469866
39LMTK20.88228065
40TIE10.87507966
41WNK40.83399625
42NUAK10.82376766
43PAK20.82117764
44BCKDK0.80601880
45RET0.79317249
46BCR0.73415630
47EEF2K0.72748800
48PIM20.72370670
49MAPK40.66377456
50BRSK20.65973930
51MAPK120.63600068
52EIF2AK10.63332316
53PLK40.62120958
54RPS6KB20.61619931
55CAMK10.61064341
56CAMK2D0.59146356
57ROCK20.59089037
58ICK0.57683269
59MAPK70.57316403
60WNK10.56508927
61PRKCE0.56157763
62FGFR10.55279661
63PINK10.53063933
64MAP2K10.53047295
65PLK20.52730615
66PRKD10.50573743
67MAP3K30.49504724
68AKT20.47832581
69EPHB20.46655695
70MAP2K30.46518582
71PTK60.46467869
72BMX0.45871536
73MARK30.45773976
74MAP3K70.45425901
75EPHB10.44499794
76AKT30.44117894
77PRKG20.43804809
78PRKG10.43658513
79CAMK2A0.43552334
80MARK20.43454177
81BRSK10.43248076
82TAOK10.42345544
83ARAF0.40576269
84CDK140.40482198
85DYRK1B0.40252736
86PRKACG0.40065510
87JAK20.39562100
88CDK180.38401521
89CDK40.37628587
90PRKACB0.36694408
91STK380.36555715
92PRPF4B0.36079194
93LATS20.35697189
94CDK150.35378226
95KSR10.34859312
96RIPK10.34688955
97RAF10.34033025
98PDK20.33695822
99PRKAA10.33265088
100EPHA30.31856828
101PAK40.30787104
102STK390.29564198
103PAK10.28827123
104LATS10.28632609
105AURKB0.28114926
106CDK11A0.27989234
107FER0.27707518
108PRKAA20.27480301
109MAPK100.26718254
110PDK10.26654076
111MAP3K60.25649741
112EGFR0.25507111
113MTOR0.25179841
114RPS6KC10.24583050
115RPS6KL10.24583050
116NEK90.23131559
117RPS6KA20.22995227
118MINK10.22922389
119CDK80.22100877
120LRRK20.22088810
121PKN10.22088135
122PRKACA0.21952202
123MAP3K110.21895338
124MELK0.20855743
125CAMK2G0.20685067
126KDR0.19052784
127CCNB10.17444504
128RPS6KA60.16800633
129RPS6KA10.16732407
130PRKCQ0.16699150
131SRPK10.15054589
132PLK30.14815154
133UHMK10.14568040
134CLK10.12572937

Predicted pathways (KEGG)

RankGene SetZ-score
1* Cardiac muscle contraction_Homo sapiens_hsa042605.80549289
2Citrate cycle (TCA cycle)_Homo sapiens_hsa000204.97687891
3Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054104.95893897
4Dilated cardiomyopathy_Homo sapiens_hsa054144.68428953
5Parkinsons disease_Homo sapiens_hsa050123.92621108
6Oxidative phosphorylation_Homo sapiens_hsa001903.71210469
72-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.74725077
8Huntingtons disease_Homo sapiens_hsa050162.71874362
9Alzheimers disease_Homo sapiens_hsa050102.71445933
10Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.68908297
11Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.40133831
12Carbon metabolism_Homo sapiens_hsa012002.36943704
13Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.18161543
14Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.17635446
15* Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042612.17233668
16Tight junction_Homo sapiens_hsa045301.75478546
17Biosynthesis of amino acids_Homo sapiens_hsa012301.74912477
18Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.48777407
19Propanoate metabolism_Homo sapiens_hsa006401.42456453
20cGMP-PKG signaling pathway_Homo sapiens_hsa040221.42296510
21HIF-1 signaling pathway_Homo sapiens_hsa040661.41720365
22Pyruvate metabolism_Homo sapiens_hsa006201.33708079
23Central carbon metabolism in cancer_Homo sapiens_hsa052301.27201770
24Galactose metabolism_Homo sapiens_hsa000521.26153040
25Protein digestion and absorption_Homo sapiens_hsa049741.22559316
26Viral myocarditis_Homo sapiens_hsa054161.22010564
27Glucagon signaling pathway_Homo sapiens_hsa049221.19294000
28Focal adhesion_Homo sapiens_hsa045101.10191233
29Fructose and mannose metabolism_Homo sapiens_hsa000511.09089563
30Proteasome_Homo sapiens_hsa030501.08866943
31Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.02758488
32Vascular smooth muscle contraction_Homo sapiens_hsa042701.02298789
33Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.95221378
34Oxytocin signaling pathway_Homo sapiens_hsa049210.94659339
35Fatty acid degradation_Homo sapiens_hsa000710.90336099
36Leukocyte transendothelial migration_Homo sapiens_hsa046700.89053446
37Adherens junction_Homo sapiens_hsa045200.86045166
38Hippo signaling pathway_Homo sapiens_hsa043900.84486337
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.82156669
40Starch and sucrose metabolism_Homo sapiens_hsa005000.75911822
41Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.75586255
42Gastric acid secretion_Homo sapiens_hsa049710.74648424
43Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.71778645
44Ovarian steroidogenesis_Homo sapiens_hsa049130.70698078
45Proteoglycans in cancer_Homo sapiens_hsa052050.69639163
46Fatty acid metabolism_Homo sapiens_hsa012120.68043934
47Circadian rhythm_Homo sapiens_hsa047100.65379417
48TGF-beta signaling pathway_Homo sapiens_hsa043500.64018960
49Gap junction_Homo sapiens_hsa045400.63865879
50Pancreatic secretion_Homo sapiens_hsa049720.63509134
51Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.62975137
52Basal cell carcinoma_Homo sapiens_hsa052170.62138273
53Malaria_Homo sapiens_hsa051440.60032459
54Insulin resistance_Homo sapiens_hsa049310.56954322
55Insulin signaling pathway_Homo sapiens_hsa049100.56817748
56Calcium signaling pathway_Homo sapiens_hsa040200.54799295
57Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.53646438
58AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.52247438
59Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.50314697
60Phospholipase D signaling pathway_Homo sapiens_hsa040720.49798097
61GnRH signaling pathway_Homo sapiens_hsa049120.48806268
62Regulation of actin cytoskeleton_Homo sapiens_hsa048100.47984941
63RNA degradation_Homo sapiens_hsa030180.47930622
64Tyrosine metabolism_Homo sapiens_hsa003500.47779200
65Pentose phosphate pathway_Homo sapiens_hsa000300.47126790
66Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.46341819
67Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.46235381
68Fatty acid elongation_Homo sapiens_hsa000620.46168900
69Phenylalanine metabolism_Homo sapiens_hsa003600.46117743
70PPAR signaling pathway_Homo sapiens_hsa033200.44745405
71Cell cycle_Homo sapiens_hsa041100.44236511
72Cholinergic synapse_Homo sapiens_hsa047250.43729001
73Type II diabetes mellitus_Homo sapiens_hsa049300.43713093
74Melanogenesis_Homo sapiens_hsa049160.41828123
75Bile secretion_Homo sapiens_hsa049760.41485348
76Oocyte meiosis_Homo sapiens_hsa041140.41173957
77Hedgehog signaling pathway_Homo sapiens_hsa043400.40884836
78Mismatch repair_Homo sapiens_hsa034300.40282093
79Aldosterone synthesis and secretion_Homo sapiens_hsa049250.39557761
80Circadian entrainment_Homo sapiens_hsa047130.39528388
81ECM-receptor interaction_Homo sapiens_hsa045120.37951186
82VEGF signaling pathway_Homo sapiens_hsa043700.36117216
83Prion diseases_Homo sapiens_hsa050200.35080927
84Pancreatic cancer_Homo sapiens_hsa052120.33851835
85Mineral absorption_Homo sapiens_hsa049780.33612715
86Non-small cell lung cancer_Homo sapiens_hsa052230.33545644
87Wnt signaling pathway_Homo sapiens_hsa043100.32824389
88Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.31862371
89Chronic myeloid leukemia_Homo sapiens_hsa052200.31716533
90Taste transduction_Homo sapiens_hsa047420.31469843
91Thyroid hormone synthesis_Homo sapiens_hsa049180.30559544
92Carbohydrate digestion and absorption_Homo sapiens_hsa049730.30321169
93Salivary secretion_Homo sapiens_hsa049700.30110518
94Melanoma_Homo sapiens_hsa052180.29227901
95Olfactory transduction_Homo sapiens_hsa047400.29171228
96HTLV-I infection_Homo sapiens_hsa051660.26782706
97Metabolic pathways_Homo sapiens_hsa011000.25519145
98Rap1 signaling pathway_Homo sapiens_hsa040150.25498968
99Endometrial cancer_Homo sapiens_hsa052130.23364278
100Acute myeloid leukemia_Homo sapiens_hsa052210.22276552
101cAMP signaling pathway_Homo sapiens_hsa040240.21163758
102Thyroid hormone signaling pathway_Homo sapiens_hsa049190.20966705
103AMPK signaling pathway_Homo sapiens_hsa041520.20326128
104mTOR signaling pathway_Homo sapiens_hsa041500.18477730
105Purine metabolism_Homo sapiens_hsa002300.18464929
106Cysteine and methionine metabolism_Homo sapiens_hsa002700.18012295
107RNA polymerase_Homo sapiens_hsa030200.17321536
108GABAergic synapse_Homo sapiens_hsa047270.17180245
109FoxO signaling pathway_Homo sapiens_hsa040680.17112426
110Amphetamine addiction_Homo sapiens_hsa050310.16411060
111Insulin secretion_Homo sapiens_hsa049110.16264514
112MAPK signaling pathway_Homo sapiens_hsa040100.15592744
113Long-term potentiation_Homo sapiens_hsa047200.15541781
114mRNA surveillance pathway_Homo sapiens_hsa030150.14950891
115Homologous recombination_Homo sapiens_hsa034400.14872885
116Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.14520023
117Amoebiasis_Homo sapiens_hsa051460.14158530
118Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.13772200
119Pathways in cancer_Homo sapiens_hsa052000.13576131
120Adipocytokine signaling pathway_Homo sapiens_hsa049200.13234499
121Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.12125066
122Ribosome_Homo sapiens_hsa030100.11652418
123Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.10978597
124Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.09499285
125Renin secretion_Homo sapiens_hsa049240.09206983
126RNA transport_Homo sapiens_hsa030130.09200334
127Longevity regulating pathway - mammal_Homo sapiens_hsa042110.07419680
128Platelet activation_Homo sapiens_hsa046110.06892384
129Small cell lung cancer_Homo sapiens_hsa052220.06374264
130MicroRNAs in cancer_Homo sapiens_hsa052060.06026192
131Dopaminergic synapse_Homo sapiens_hsa047280.06008651
132Epstein-Barr virus infection_Homo sapiens_hsa051690.05397815
133Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.04108434
134PI3K-Akt signaling pathway_Homo sapiens_hsa041510.03621723
135Base excision repair_Homo sapiens_hsa034100.03346052
136Renal cell carcinoma_Homo sapiens_hsa052110.02822525
137Nucleotide excision repair_Homo sapiens_hsa034200.01676913
138Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.01563124

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