MYCBPAP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1acrosome assembly (GO:0001675)9.99880251
2motile cilium assembly (GO:0044458)9.96500494
3multicellular organism reproduction (GO:0032504)9.95204969
4binding of sperm to zona pellucida (GO:0007339)9.49520552
5plasma membrane fusion (GO:0045026)9.48548518
6cell wall macromolecule catabolic process (GO:0016998)9.24253062
7cell wall macromolecule metabolic process (GO:0044036)9.24253062
8cell-cell recognition (GO:0009988)9.21941166
9spermatid development (GO:0007286)9.08578426
10epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)9.03878894
11regulation of cilium movement (GO:0003352)9.02597665
12piRNA metabolic process (GO:0034587)8.38942536
13reproduction (GO:0000003)8.29909316
14male meiosis (GO:0007140)7.33595969
15synaptonemal complex organization (GO:0070193)7.17857199
16single fertilization (GO:0007338)7.08185837
17ventricular system development (GO:0021591)6.94741149
18negative regulation of inclusion body assembly (GO:0090084)6.78080716
19synaptonemal complex assembly (GO:0007130)6.64788941
20sperm capacitation (GO:0048240)6.44483075
21response to pheromone (GO:0019236)6.12700294
22* spermatogenesis (GO:0007283)6.07715083
23fertilization (GO:0009566)6.07619458
24* male gamete generation (GO:0048232)6.05431792
25regulation of inclusion body assembly (GO:0090083)5.68561487
26male meiosis I (GO:0007141)5.68074866
27organic cation transport (GO:0015695)5.60520574
28* gamete generation (GO:0007276)5.55423971
29regulation of microtubule-based movement (GO:0060632)5.49834102
30microtubule depolymerization (GO:0007019)5.47030662
31axoneme assembly (GO:0035082)5.41680806
32DNA methylation involved in gamete generation (GO:0043046)5.31771909
33germ cell development (GO:0007281)5.10046019
34cellular process involved in reproduction in multicellular organism (GO:0022412)4.99590419
35microtubule severing (GO:0051013)4.96831552
36calcium ion-dependent exocytosis (GO:0017156)4.85952598
37left/right pattern formation (GO:0060972)4.81808480
38cellular ketone body metabolic process (GO:0046950)4.66239635
39meiosis I (GO:0007127)4.56785261
40nucleoside diphosphate phosphorylation (GO:0006165)4.47823180
41cell recognition (GO:0008037)4.47766439
42chromosome organization involved in meiosis (GO:0070192)4.47106821
43seminiferous tubule development (GO:0072520)4.44067957
44* multicellular organismal reproductive process (GO:0048609)4.40778182
45meiotic nuclear division (GO:0007126)4.40749099
46GTP biosynthetic process (GO:0006183)4.36062391
47ketone body metabolic process (GO:1902224)4.25305088
48intraciliary transport (GO:0042073)4.18753511
49behavioral response to nicotine (GO:0035095)4.18042496
50glycerol ether metabolic process (GO:0006662)4.08612289
51protein localization to cilium (GO:0061512)4.07491457
52protein polyglutamylation (GO:0018095)3.92971915
53cilium organization (GO:0044782)3.86484168
54UTP biosynthetic process (GO:0006228)3.84655343
55meiotic cell cycle (GO:0051321)3.84258776
56chaperone-mediated protein complex assembly (GO:0051131)3.81466543
57genitalia morphogenesis (GO:0035112)3.80149180
58ether metabolic process (GO:0018904)3.76709081
59microtubule-based movement (GO:0007018)3.69403935
60left/right axis specification (GO:0070986)3.68314565
61cilium assembly (GO:0042384)3.66453187
62protein refolding (GO:0042026)3.55514649
63L-fucose catabolic process (GO:0042355)3.54825521
64fucose catabolic process (GO:0019317)3.54825521
65L-fucose metabolic process (GO:0042354)3.54825521
66chromosome condensation (GO:0030261)3.51539763
67UTP metabolic process (GO:0046051)3.50586051
68DNA packaging (GO:0006323)3.45917730
69cilium morphogenesis (GO:0060271)3.45704220
70* multicellular organismal development (GO:0007275)3.43038257
71detection of light stimulus involved in sensory perception (GO:0050962)3.41911579
72detection of light stimulus involved in visual perception (GO:0050908)3.41911579
73cellular component assembly involved in morphogenesis (GO:0010927)3.40213140
74indole-containing compound catabolic process (GO:0042436)3.37188025
75indolalkylamine catabolic process (GO:0046218)3.37188025
76tryptophan catabolic process (GO:0006569)3.37188025
77nonmotile primary cilium assembly (GO:0035058)3.31352892
78photoreceptor cell maintenance (GO:0045494)3.29554381
79indolalkylamine metabolic process (GO:0006586)3.27366672
80detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.26117291
81retinal cone cell development (GO:0046549)3.25026072
82guanosine-containing compound biosynthetic process (GO:1901070)3.21358823
83interferon-gamma secretion (GO:0072643)3.20619805
84spermatid nucleus differentiation (GO:0007289)3.16713124
85centriole replication (GO:0007099)3.11010354
86kynurenine metabolic process (GO:0070189)3.10178546
87DNA deamination (GO:0045006)3.07901977
88establishment of protein localization to Golgi (GO:0072600)3.07883626
89negative regulation of organelle assembly (GO:1902116)3.06317063
90neural tube formation (GO:0001841)3.01309383
91carnitine transport (GO:0015879)3.00357950
92amino-acid betaine transport (GO:0015838)3.00357950
93monoubiquitinated protein deubiquitination (GO:0035520)3.00103506
94RNA localization (GO:0006403)2.99662616
95alditol metabolic process (GO:0019400)2.97766460
96gene silencing by RNA (GO:0031047)2.96556754
97glycolytic process (GO:0006096)2.93040204
98CTP biosynthetic process (GO:0006241)2.91784071
99CTP metabolic process (GO:0046036)2.91784071
100polyol catabolic process (GO:0046174)2.90987241
101tryptophan metabolic process (GO:0006568)2.87340001
102carnitine transmembrane transport (GO:1902603)2.86647216
103lactate metabolic process (GO:0006089)2.84706707
104microtubule bundle formation (GO:0001578)2.83919038
105meiotic cell cycle process (GO:1903046)2.80045682
106protein targeting to Golgi (GO:0000042)2.80002350
107microtubule polymerization or depolymerization (GO:0031109)2.78320729
108negative regulation of telomere maintenance (GO:0032205)2.75109151
109phosphatidylethanolamine metabolic process (GO:0046337)2.73717978
110phosphatidylethanolamine biosynthetic process (GO:0006646)2.73606120
111protein localization to Golgi apparatus (GO:0034067)2.71233283
112spinal cord motor neuron differentiation (GO:0021522)2.70749904
113centriole assembly (GO:0098534)2.70014365
114regulation of action potential (GO:0098900)2.67088877
115pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.63704124
116protein K11-linked deubiquitination (GO:0035871)2.62982143
117behavioral response to ethanol (GO:0048149)2.62710214
118water-soluble vitamin biosynthetic process (GO:0042364)2.61657993
119protein complex biogenesis (GO:0070271)2.60946641
120platelet dense granule organization (GO:0060155)2.60607820
121auditory receptor cell stereocilium organization (GO:0060088)2.58738803
122negative regulation of mast cell activation (GO:0033004)2.57948342
123regulation of spindle checkpoint (GO:0090231)2.57750850
124amine catabolic process (GO:0009310)2.57741462
125cellular biogenic amine catabolic process (GO:0042402)2.57741462
126preassembly of GPI anchor in ER membrane (GO:0016254)2.57022784
127reciprocal meiotic recombination (GO:0007131)2.56744526
128reciprocal DNA recombination (GO:0035825)2.56744526
129neuronal action potential (GO:0019228)2.56637393
130synapsis (GO:0007129)2.54970674
131regulation of meiosis I (GO:0060631)2.54644433
132photoreceptor cell development (GO:0042461)2.53367341
133reflex (GO:0060004)2.52112296
134single strand break repair (GO:0000012)2.51827317
135sexual reproduction (GO:0019953)2.51374528
136NADH dehydrogenase complex assembly (GO:0010257)2.49058285
137mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.49058285
138mitochondrial respiratory chain complex I assembly (GO:0032981)2.49058285
139exogenous drug catabolic process (GO:0042738)2.47671105
140glycerol metabolic process (GO:0006071)2.46992386
141G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.46055800
142pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.45711606
143retrograde transport, vesicle recycling within Golgi (GO:0000301)2.45433780
144regulation of glucokinase activity (GO:0033131)2.44983136
145regulation of hexokinase activity (GO:1903299)2.44983136
146inner ear receptor stereocilium organization (GO:0060122)2.44946106
147cell projection assembly (GO:0030031)2.42434595
148indole-containing compound metabolic process (GO:0042430)2.42350062
149mannosylation (GO:0097502)2.41194646
150cilium or flagellum-dependent cell motility (GO:0001539)12.9578946
151sperm motility (GO:0030317)12.5981794
152fusion of sperm to egg plasma membrane (GO:0007342)12.4593210
153axonemal dynein complex assembly (GO:0070286)12.3540139
154epithelial cilium movement (GO:0003351)11.1906590
155cilium movement (GO:0003341)10.6379558
156acrosome reaction (GO:0007340)10.6039774
157sperm-egg recognition (GO:0035036)10.3155624

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.35110995
2EZH2_22144423_ChIP-Seq_EOC_Human4.75283323
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.54512294
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.86730320
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.78252389
6GBX2_23144817_ChIP-Seq_PC3_Human2.59230184
7GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.36520857
8IGF1R_20145208_ChIP-Seq_DFB_Human2.35185308
9CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.33194516
10STAT6_21828071_ChIP-Seq_BEAS2B_Human2.32126438
11EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.25172052
12VDR_22108803_ChIP-Seq_LS180_Human2.23212692
13CTBP1_25329375_ChIP-Seq_LNCAP_Human2.19093412
14FUS_26573619_Chip-Seq_HEK293_Human2.15999193
15POU3F2_20337985_ChIP-ChIP_501MEL_Human2.15365821
16* PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.11486206
17ER_23166858_ChIP-Seq_MCF-7_Human2.02505050
18TAF15_26573619_Chip-Seq_HEK293_Human2.00475570
19ZNF274_21170338_ChIP-Seq_K562_Hela1.97562443
20* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.96889423
21P300_19829295_ChIP-Seq_ESCs_Human1.94781250
22GATA1_26923725_Chip-Seq_HPCs_Mouse1.93960824
23FLI1_27457419_Chip-Seq_LIVER_Mouse1.86859764
24FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.82826981
25ELK4_26923725_Chip-Seq_MESODERM_Mouse1.77724571
26EWS_26573619_Chip-Seq_HEK293_Human1.71357980
27ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.70459610
28PCGF2_27294783_Chip-Seq_ESCs_Mouse1.69846063
29WDR5_24793694_ChIP-Seq_LNCAP_Human1.69419467
30MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.69291907
31STAT1_17558387_ChIP-Seq_HELA_Human1.67021521
32TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.63806792
33UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.61938010
34KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.60508911
35HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.58896750
36STAT3_23295773_ChIP-Seq_U87_Human1.54505879
37AR_25329375_ChIP-Seq_VCAP_Human1.52700044
38CBP_20019798_ChIP-Seq_JUKART_Human1.52305386
39IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.52305386
40SOX2_22085726_ChIP-Seq_NPCs_Mouse1.51918636
41AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.50792022
42RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.48242405
43FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.46914299
44PIAS1_25552417_ChIP-Seq_VCAP_Human1.45231030
45TP53_22573176_ChIP-Seq_HFKS_Human1.44631566
46NR3C1_21868756_ChIP-Seq_MCF10A_Human1.42627746
47SOX2_19829295_ChIP-Seq_ESCs_Human1.42472256
48NANOG_19829295_ChIP-Seq_ESCs_Human1.42472256
49CTBP2_25329375_ChIP-Seq_LNCAP_Human1.42408037
50TOP2B_26459242_ChIP-Seq_MCF-7_Human1.41880474
51GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.40530419
52CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.40353623
53SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.39010594
54KAP1_22055183_ChIP-Seq_ESCs_Mouse1.37956485
55* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.37023292
56BMI1_23680149_ChIP-Seq_NPCS_Mouse1.36705348
57TAL1_26923725_Chip-Seq_HPCs_Mouse1.35803153
58REST_21632747_ChIP-Seq_MESCs_Mouse1.35374050
59PCGF2_27294783_Chip-Seq_NPCs_Mouse1.35082774
60GATA3_21878914_ChIP-Seq_MCF-7_Human1.34979007
61SALL1_21062744_ChIP-ChIP_HESCs_Human1.33442436
62TCF4_22108803_ChIP-Seq_LS180_Human1.31957304
63SMAD3_21741376_ChIP-Seq_EPCs_Human1.31578978
64* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.31058487
65ERG_20517297_ChIP-Seq_VCAP_Human1.30971212
66PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.30697703
67KDM2B_26808549_Chip-Seq_REH_Human1.30688067
68GATA3_21867929_ChIP-Seq_CD8_Mouse1.30086046
69NCOR_22424771_ChIP-Seq_293T_Human1.30070991
70HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.29551268
71TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.28724865
72FOXA1_21572438_ChIP-Seq_LNCaP_Human1.28605055
73MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.27819241
74* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.27167423
75GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.27142859
76IRF1_19129219_ChIP-ChIP_H3396_Human1.27118623
77LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.26356357
78SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.25699374
79RUNX2_22187159_ChIP-Seq_PCA_Human1.24597910
80NFE2_27457419_Chip-Seq_LIVER_Mouse1.24557427
81* P53_21459846_ChIP-Seq_SAOS-2_Human1.23814228
82CBX2_27304074_Chip-Seq_ESCs_Mouse1.23764898
83RBPJ_22232070_ChIP-Seq_NCS_Mouse1.23301289
84FLI1_21867929_ChIP-Seq_TH2_Mouse1.23090243
85PRDM14_20953172_ChIP-Seq_ESCs_Human1.22204316
86* ETV2_25802403_ChIP-Seq_MESCs_Mouse1.22153969
87EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.21961872
88TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.20480603
89FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.19837010
90SUZ12_27294783_Chip-Seq_NPCs_Mouse1.19793099
91MYC_19829295_ChIP-Seq_ESCs_Human1.19347007
92AR_20517297_ChIP-Seq_VCAP_Human1.19036823
93EZH2_27294783_Chip-Seq_NPCs_Mouse1.18507778
94NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.18502377
95RAD21_21589869_ChIP-Seq_MESCs_Mouse1.18417041
96HOXB7_26014856_ChIP-Seq_BT474_Human1.17792595
97ERA_21632823_ChIP-Seq_H3396_Human1.17376103
98AUTS2_25519132_ChIP-Seq_293T-REX_Human1.16271438
99PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.13485605
100NANOG_20526341_ChIP-Seq_ESCs_Human1.13430174
101* CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.12871932
102TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12613680
103POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.12613680
104SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.12402788
105TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.12230743
106ETV1_20927104_ChIP-Seq_GIST48_Human1.12080929
107TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11800945
108MYC_18940864_ChIP-ChIP_HL60_Human1.11294296
109EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.11266702
110PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.11026129
111* DROSHA_22980978_ChIP-Seq_HELA_Human1.10548719
112AR_21572438_ChIP-Seq_LNCaP_Human1.10488501
113RNF2_27304074_Chip-Seq_NSC_Mouse1.09942101
114GATA3_21867929_ChIP-Seq_TH1_Mouse1.09599579
115GF1_26923725_Chip-Seq_HPCs_Mouse1.07458052
116GABP_17652178_ChIP-ChIP_JURKAT_Human1.06733407
117SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.05583488
118NANOG_18555785_Chip-Seq_ESCs_Mouse1.04682284
119OCT4_20526341_ChIP-Seq_ESCs_Human1.03888160
120CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.03761837
121FOXH1_21741376_ChIP-Seq_EPCs_Human1.02904223
122MYC_27129775_Chip-Seq_CORNEA_Mouse1.02839722
123CRX_20693478_ChIP-Seq_RETINA_Mouse1.02151726
124RBPJ_21746931_ChIP-Seq_IB4_Human1.01692063
125PHF8_20622853_ChIP-Seq_HELA_Human1.01493985
126RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.99145654
127CDX2_22108803_ChIP-Seq_LS180_Human0.98826472
128TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.98748065
129MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.98226037
130RUNX1_26923725_Chip-Seq_HPCs_Mouse0.97267749
131SMAD4_21741376_ChIP-Seq_EPCs_Human0.96980675
132TBL1_22424771_ChIP-Seq_293T_Human0.95851988
133NFYB_21822215_ChIP-Seq_K562_Human0.95849624
134OCT4_18555785_Chip-Seq_ESCs_Mouse0.95150637
135CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.94282920
136CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.92693820
137P53_22387025_ChIP-Seq_ESCs_Mouse0.92457377
138CTCF_20526341_ChIP-Seq_ESCs_Human0.92181895
139EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.90713109
140* CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.90462954
141* SPI1_26923725_Chip-Seq_HPCs_Mouse0.90173515
142SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.90035420
143FOXA1_27270436_Chip-Seq_PROSTATE_Human0.87972171
144FOXA1_25329375_ChIP-Seq_VCAP_Human0.87972171
145SMAD3_21741376_ChIP-Seq_ESCs_Human0.87486187
146ZFP57_27257070_Chip-Seq_ESCs_Mouse0.87370920
147FLI1_21867929_ChIP-Seq_CD8_Mouse0.87139289
148BCAT_22108803_ChIP-Seq_LS180_Human0.86783300
149OCT4_21477851_ChIP-Seq_ESCs_Mouse0.86771436
150KLF4_18555785_Chip-Seq_ESCs_Mouse0.86293759
151ESET_19884257_ChIP-Seq_ESCs_Mouse0.86097334
152GATA1_19941827_ChIP-Seq_MEL86_Mouse0.85210744
153ESRRB_18555785_Chip-Seq_ESCs_Mouse0.84296311
154YY1_22570637_ChIP-Seq_MALME-3M_Human0.84205027
155CMYC_18555785_Chip-Seq_ESCs_Mouse0.84163351
156STAT3_18555785_ChIP-Seq_MESCs_Mouse0.82780747
157* SOX11_22085726_ChIP-Seq_ESNs_Mouse0.82725420
158SOX2_21211035_ChIP-Seq_LN229_Human0.82408122
159SMAD4_21799915_ChIP-Seq_A2780_Human0.82331100
160* TCF4_23295773_ChIP-Seq_U87_Human0.82177629

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.77514010
2MP0001929_abnormal_gametogenesis5.24619507
3MP0008877_abnormal_DNA_methylation4.44880478
4MP0002653_abnormal_ependyma_morphology3.39758226
5MP0002210_abnormal_sex_determination3.35800950
6MP0002161_abnormal_fertility/fecundity3.11701594
7MP0001145_abnormal_male_reproductive2.86850518
8MP0008875_abnormal_xenobiotic_pharmacok2.58590001
9MP0000653_abnormal_sex_gland2.46172932
10MP0002102_abnormal_ear_morphology2.45530886
11MP0005670_abnormal_white_adipose2.33830648
12MP0003195_calcinosis2.26198148
13MP0005623_abnormal_meninges_morphology2.14444643
14MP0008004_abnormal_stomach_pH2.05687457
15MP0005410_abnormal_fertilization14.8787815
16MP0000569_abnormal_digit_pigmentation1.89278156
17MP0006292_abnormal_olfactory_placode1.83759608
18MP0009745_abnormal_behavioral_response1.78149850
19MP0000372_irregular_coat_pigmentation1.77909163
20MP0002837_dystrophic_cardiac_calcinosis1.77184268
21MP0008872_abnormal_physiological_respon1.74787140
22MP0002160_abnormal_reproductive_system1.74752771
23MP0005645_abnormal_hypothalamus_physiol1.70931493
24MP0001501_abnormal_sleep_pattern1.70527650
25MP0003787_abnormal_imprinting1.63597798
26MP0003136_yellow_coat_color1.63410275
27MP0005377_hearing/vestibular/ear_phenot1.59937306
28MP0003878_abnormal_ear_physiology1.59937306
29MP0003011_delayed_dark_adaptation1.57374479
30MP0001486_abnormal_startle_reflex1.57138415
31MP0001485_abnormal_pinna_reflex1.55044434
32MP0006276_abnormal_autonomic_nervous1.54035868
33MP0001765_abnormal_ion_homeostasis1.54023906
34MP0002272_abnormal_nervous_system1.51124731
35MP0002638_abnormal_pupillary_reflex1.50744041
36MP0003646_muscle_fatigue1.50084106
37MP0004142_abnormal_muscle_tone1.45482663
38MP0004885_abnormal_endolymph1.43880849
39MP0002282_abnormal_trachea_morphology1.38618656
40MP0002735_abnormal_chemical_nociception1.37212362
41MP0005084_abnormal_gallbladder_morpholo1.36712812
42MP0003880_abnormal_central_pattern1.32810592
43MP0003718_maternal_effect1.32422159
44MP0008789_abnormal_olfactory_epithelium1.27960294
45MP0008995_early_reproductive_senescence1.25746503
46MP0002572_abnormal_emotion/affect_behav1.21754732
47MP0001970_abnormal_pain_threshold1.21724786
48MP0002733_abnormal_thermal_nociception1.21675593
49MP0001905_abnormal_dopamine_level1.21599854
50MP0005647_abnormal_sex_gland1.20294786
51MP0000427_abnormal_hair_cycle1.18754195
52MP0002557_abnormal_social/conspecific_i1.17265414
53MP0004147_increased_porphyrin_level1.16253776
54MP0002138_abnormal_hepatobiliary_system1.13923620
55MP0002132_abnormal_respiratory_system1.13180350
56MP0002277_abnormal_respiratory_mucosa1.12752145
57MP0001529_abnormal_vocalization1.11998184
58MP0004233_abnormal_muscle_weight1.11043221
59MP0005174_abnormal_tail_pigmentation1.08778137
60MP0004019_abnormal_vitamin_homeostasis1.07578827
61MP0002064_seizures1.05681564
62MP0002163_abnormal_gland_morphology1.05423118
63MP0002067_abnormal_sensory_capabilities1.02188353
64MP0000383_abnormal_hair_follicle0.99250229
65MP0005389_reproductive_system_phenotype0.99161907
66MP0000026_abnormal_inner_ear0.98902711
67MP0001984_abnormal_olfaction0.98868427
68MP0002928_abnormal_bile_duct0.98550654
69MP0005075_abnormal_melanosome_morpholog0.98254844
70MP0001963_abnormal_hearing_physiology0.96624496
71MP0005195_abnormal_posterior_eye0.94998958
72MP0000013_abnormal_adipose_tissue0.94544224
73MP0010386_abnormal_urinary_bladder0.91248543
74MP0005666_abnormal_adipose_tissue0.90320947
75MP0003635_abnormal_synaptic_transmissio0.86474665
76MP0004145_abnormal_muscle_electrophysio0.85889323
77MP0003252_abnormal_bile_duct0.85215704
78MP0005386_behavior/neurological_phenoty0.83768455
79MP0004924_abnormal_behavior0.83768455
80MP0009046_muscle_twitch0.83562070
81MP0002752_abnormal_somatic_nervous0.82362432
82MP0002938_white_spotting0.81651301
83MP0002063_abnormal_learning/memory/cond0.80612743
84MP0000230_abnormal_systemic_arterial0.80347056
85MP0002095_abnormal_skin_pigmentation0.78899357
86MP0005394_taste/olfaction_phenotype0.78664729
87MP0005499_abnormal_olfactory_system0.78664729
88MP0001502_abnormal_circadian_rhythm0.78432884
89MP0003786_premature_aging0.78263572
90MP0005423_abnormal_somatic_nervous0.74723054
91MP0003959_abnormal_lean_body0.74678711
92MP0001958_emphysema0.73529746
93MP0005636_abnormal_mineral_homeostasis0.71420508
94MP0003879_abnormal_hair_cell0.70833711
95MP0001440_abnormal_grooming_behavior0.67627415
96MP0001986_abnormal_taste_sensitivity0.67060835
97MP0001764_abnormal_homeostasis0.66802045
98MP0008058_abnormal_DNA_repair0.66796560
99MP0005551_abnormal_eye_electrophysiolog0.65915540
100MP0002909_abnormal_adrenal_gland0.65811690
101MP0005253_abnormal_eye_physiology0.63893209
102MP0003115_abnormal_respiratory_system0.62328062
103MP0002234_abnormal_pharynx_morphology0.62256413
104MP0005646_abnormal_pituitary_gland0.61981950
105MP0001661_extended_life_span0.61222076
106MP0004043_abnormal_pH_regulation0.57316268
107MP0000534_abnormal_ureter_morphology0.57242198
108MP0004133_heterotaxia0.55589966
109MP0005375_adipose_tissue_phenotype0.55586445
110MP0002295_abnormal_pulmonary_circulatio0.54382759
111MP0002971_abnormal_brown_adipose0.52588542
112MP0004036_abnormal_muscle_relaxation0.51770428
113MP0001944_abnormal_pancreas_morphology0.49763587
114MP0003329_amyloid_beta_deposits0.47161037
115MP0009115_abnormal_fat_cell0.46807496
116MP0000358_abnormal_cell_content/0.45980251
117MP0003942_abnormal_urinary_system0.45761671
118MP0002876_abnormal_thyroid_physiology0.44711504
119MP0001324_abnormal_eye_pigmentation0.44020936
120MP0002168_other_aberrant_phenotype0.43981735
121MP0002693_abnormal_pancreas_physiology0.42164980
122MP0004270_analgesia0.42077607
123MP0002736_abnormal_nociception_after0.41685259
124MP0003699_abnormal_female_reproductive0.40526784
125MP0005391_vision/eye_phenotype0.39725814
126MP0000003_abnormal_adipose_tissue0.39037784
127MP0006072_abnormal_retinal_apoptosis0.38880503
128MP0004742_abnormal_vestibular_system0.37090434
129MP0003953_abnormal_hormone_level0.36498556
130MP0004264_abnormal_extraembryonic_tissu0.36446546
131MP0001270_distended_abdomen0.35861934
132MP0005379_endocrine/exocrine_gland_phen0.35847963
133MP0003633_abnormal_nervous_system0.34595104
134MP0001293_anophthalmia0.34259158
135MP0000631_abnormal_neuroendocrine_gland0.34041038
136MP0003950_abnormal_plasma_membrane0.34020802
137MP0001727_abnormal_embryo_implantation0.32496722
138MP0003861_abnormal_nervous_system0.32444131
139MP0001756_abnormal_urination0.32217002
140MP0000537_abnormal_urethra_morphology0.30366820
141MP0002269_muscular_atrophy0.29844304
142MP0002133_abnormal_respiratory_system0.29721035
143MP0005388_respiratory_system_phenotype0.29721035
144MP0002152_abnormal_brain_morphology0.29650464
145MP0002108_abnormal_muscle_morphology0.28822007
146MP0002229_neurodegeneration0.28514940
147MP0003948_abnormal_gas_homeostasis0.28486789
148MP0001968_abnormal_touch/_nociception0.26594973
149MP0003631_nervous_system_phenotype0.26087278
150MP0003183_abnormal_peptide_metabolism0.25168364
151MP0005535_abnormal_body_temperature0.24642449
152MP0004811_abnormal_neuron_physiology0.24301759
153MP0003283_abnormal_digestive_organ0.24055206
154MP0002970_abnormal_white_adipose0.23967220
155MP0002734_abnormal_mechanical_nocicepti0.23771935
156MP0008961_abnormal_basal_metabolism0.23640310
157MP0009643_abnormal_urine_homeostasis0.23050312
158MP0001119_abnormal_female_reproductive0.21776880
159MP0006036_abnormal_mitochondrial_physio0.21677874
160MP0002084_abnormal_developmental_patter0.20472983

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium morphology (HP:0005938)9.26180917
2Abnormal respiratory epithelium morphology (HP:0012253)9.26180917
3Rhinitis (HP:0012384)8.58841284
4Abnormal ciliary motility (HP:0012262)8.50964936
5Chronic bronchitis (HP:0004469)7.94876891
6Infertility (HP:0000789)6.12534109
7Nasal polyposis (HP:0100582)5.85910399
8Bronchiectasis (HP:0002110)4.91079267
9Abnormality of the nasal mucosa (HP:0000433)4.89139638
10Bronchitis (HP:0012387)4.48911397
11Male infertility (HP:0003251)4.25237991
12Nephronophthisis (HP:0000090)4.18510690
13Tubulointerstitial nephritis (HP:0001970)3.67001080
14Congenital stationary night blindness (HP:0007642)3.58889505
15Abnormal rod and cone electroretinograms (HP:0008323)3.53557553
16Attenuation of retinal blood vessels (HP:0007843)3.33639191
17Recurrent sinusitis (HP:0011108)3.28224338
18Abnormality of the renal medulla (HP:0100957)3.23265313
19Recurrent otitis media (HP:0000403)3.15433288
20Absent rod-and cone-mediated responses on ERG (HP:0007688)2.98997287
21Type II lissencephaly (HP:0007260)2.92439153
22Abnormality of midbrain morphology (HP:0002418)2.86702456
23Molar tooth sign on MRI (HP:0002419)2.86702456
24Tubular atrophy (HP:0000092)2.76845267
25Abnormal spermatogenesis (HP:0008669)2.75313606
26Tubulointerstitial abnormality (HP:0001969)2.71337838
27Bony spicule pigmentary retinopathy (HP:0007737)2.68665871
28Sclerocornea (HP:0000647)2.55190575
29Severe visual impairment (HP:0001141)2.54032173
30Hyperventilation (HP:0002883)2.51078282
31Abolished electroretinogram (ERG) (HP:0000550)2.50404685
32Anencephaly (HP:0002323)2.49268665
33Male pseudohermaphroditism (HP:0000037)2.40965567
34Medial flaring of the eyebrow (HP:0010747)2.40953311
35Abnormality of macular pigmentation (HP:0008002)2.35216929
36Cerebellar dysplasia (HP:0007033)2.28329929
37Decreased circulating renin level (HP:0003351)2.27961653
38Abnormality of the dental root (HP:0006486)2.26541933
39Taurodontia (HP:0000679)2.26541933
40Abnormality of permanent molar morphology (HP:0011071)2.26541933
41Pendular nystagmus (HP:0012043)2.22438436
42Gonadotropin excess (HP:0000837)2.18298365
43Recurrent bronchitis (HP:0002837)2.18267734
44Increased corneal curvature (HP:0100692)2.16905006
45Keratoconus (HP:0000563)2.16905006
46Furrowed tongue (HP:0000221)2.16426334
47Postaxial foot polydactyly (HP:0001830)2.13418302
48Impulsivity (HP:0100710)2.11585610
49Abnormality of the dental pulp (HP:0006479)2.10329175
50Pancreatic fibrosis (HP:0100732)2.09238856
51Abnormality of molar (HP:0011077)2.09152796
52Abnormality of molar morphology (HP:0011070)2.09152796
53Abnormality of dentin (HP:0010299)2.08907792
54Stage 5 chronic kidney disease (HP:0003774)2.07119354
55Abnormality of renal excretion (HP:0011036)2.06600906
56Renal cortical cysts (HP:0000803)2.05876694
57Polydipsia (HP:0001959)2.05335779
58Abnormal drinking behavior (HP:0030082)2.05335779
59Aplasia/Hypoplasia of the spleen (HP:0010451)2.05068113
60Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.6229286
61Dynein arm defect of respiratory motile cilia (HP:0012255)12.2318318
62Absent/shortened dynein arms (HP:0200106)12.2318318
63Abnormal respiratory motile cilium physiology (HP:0012261)10.2910340
64Tubulointerstitial fibrosis (HP:0005576)1.98917745
65Congenital hepatic fibrosis (HP:0002612)1.97276097
66Gaze-evoked nystagmus (HP:0000640)1.96095737
67Poor coordination (HP:0002370)1.94941864
68Progressive cerebellar ataxia (HP:0002073)1.94679294
69Absent speech (HP:0001344)1.92341690
70Cystic liver disease (HP:0006706)1.92207459
71Fibular hypoplasia (HP:0003038)1.91322476
72Abnormality of the renal cortex (HP:0011035)1.90144714
73Asplenia (HP:0001746)1.88430123
74Aplasia/Hypoplasia of the tibia (HP:0005772)1.86836522
75Abnormality of the lower motor neuron (HP:0002366)1.86169539
76Facial cleft (HP:0002006)1.85886529
77True hermaphroditism (HP:0010459)1.85636450
78Inability to walk (HP:0002540)1.85534981
79Mitochondrial inheritance (HP:0001427)1.84692916
80Median cleft lip (HP:0000161)1.82924435
81Chronic hepatic failure (HP:0100626)1.81693448
82Abnormal biliary tract physiology (HP:0012439)1.80955074
83Bile duct proliferation (HP:0001408)1.80955074
84Decreased electroretinogram (ERG) amplitude (HP:0000654)1.80079289
85Large for gestational age (HP:0001520)1.79821228
86Azoospermia (HP:0000027)1.79456940
87Retinitis pigmentosa (HP:0000510)1.79196296
88Retinal dysplasia (HP:0007973)1.76548998
89Constricted visual fields (HP:0001133)1.76365040
90Increased CSF lactate (HP:0002490)1.74485513
91Acute necrotizing encephalopathy (HP:0006965)1.71068798
92Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.70475101
93Abnormality of alanine metabolism (HP:0010916)1.70475101
94Hyperalaninemia (HP:0003348)1.70475101
95Preaxial hand polydactyly (HP:0001177)1.69403877
96Lissencephaly (HP:0001339)1.69387007
97Genetic anticipation (HP:0003743)1.68002602
98Oculomotor apraxia (HP:0000657)1.67671148
99Broad distal phalanx of finger (HP:0009836)1.66940112
100Double outlet right ventricle (HP:0001719)1.65901839
101Congenital malformation of the right heart (HP:0011723)1.65901839
102Hepatocellular necrosis (HP:0001404)1.65840385
103Optic disc pallor (HP:0000543)1.64341314
1043-Methylglutaconic aciduria (HP:0003535)1.61373281
105Optic nerve hypoplasia (HP:0000609)1.61132005
106Cholecystitis (HP:0001082)1.60478203
107Abnormal gallbladder physiology (HP:0012438)1.60478203
108Congenital sensorineural hearing impairment (HP:0008527)1.59642248
109Broad-based gait (HP:0002136)1.59401231
110Amyotrophic lateral sclerosis (HP:0007354)1.59285152
111Hepatic necrosis (HP:0002605)1.59084573
112Postaxial hand polydactyly (HP:0001162)1.57918699
113Abnormal urine output (HP:0012590)1.57365428
114Progressive inability to walk (HP:0002505)1.57211650
115Renal dysplasia (HP:0000110)1.56537490
116Bell-shaped thorax (HP:0001591)1.56330569
117Aplasia/Hypoplasia of the tongue (HP:0010295)1.56127199
118Chronic sinusitis (HP:0011109)1.55149363
119Occipital encephalocele (HP:0002085)1.54975924
120Short ribs (HP:0000773)1.53882535
121Astigmatism (HP:0000483)1.53452097
122Dyschromatopsia (HP:0007641)1.51653517
123Choroideremia (HP:0001139)1.50008706
124Pancreatic cysts (HP:0001737)1.48072210
125Congenital primary aphakia (HP:0007707)1.42746566
126Nephropathy (HP:0000112)1.42477989
127Gait imbalance (HP:0002141)1.41485538
128Spastic tetraparesis (HP:0001285)1.41201223
129Supernumerary spleens (HP:0009799)1.41150531
130Short thorax (HP:0010306)1.40693750
131Polyuria (HP:0000103)1.39168914
132Vascular calcification (HP:0004934)1.37703519
133Hypoplasia of dental enamel (HP:0006297)1.36319514
134Hemiparesis (HP:0001269)1.32331723
135Aplasia/Hypoplasia of the lens (HP:0008063)1.31866872
136Hypoplasia of the capital femoral epiphysis (HP:0003090)1.28831567
137Hyperphosphatemia (HP:0002905)1.27531260
138Decreased central vision (HP:0007663)1.26558892
139Short nail (HP:0001799)1.24138319
140Nephrogenic diabetes insipidus (HP:0009806)1.21449910
141Hyperkalemia (HP:0002153)1.21219749
142Cardiovascular calcification (HP:0011915)1.20720249
143Heterotopia (HP:0002282)1.19696639
144Aplasia/Hypoplasia of the fibula (HP:0006492)1.18973310
145Microglossia (HP:0000171)1.17270930
146Genital tract atresia (HP:0001827)1.16639130
147Abnormality of renal resorption (HP:0011038)1.15523085
148Vaginal atresia (HP:0000148)1.13760580
149Transposition of the great arteries (HP:0001669)1.12642407
150Abnormal connection of the cardiac segments (HP:0011545)1.12642407
151Abnormal ventriculo-arterial connection (HP:0011563)1.12642407

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.77973999
2PDK47.77973999
3TESK15.72716398
4PRKD35.33605680
5PDK24.92617667
6ICK3.43248223
7PNCK3.42141018
8MAP4K23.35560406
9MAPK153.10334311
10WNK42.96960038
11ADRBK22.95877462
12ZAK2.53994171
13PTK2B2.28086837
14TAOK32.23459038
15STK392.19900060
16NUAK12.13296414
17TLK12.04759717
18MAPK131.83245357
19MAP3K41.75375046
20ACVR1B1.74567852
21TXK1.73999234
22STK381.64355193
23OXSR11.61289921
24DYRK1B1.55228084
25CASK1.53448068
26PLK21.52257380
27NEK21.38378996
28TNIK1.29535225
29WNK11.24618712
30WNK31.17135408
31CCNB11.16701306
32TRIM281.07580571
33MARK11.04993550
34PAK31.04124784
35MAP2K71.03535583
36ADRBK11.03292141
37DAPK21.03278546
38CAMKK21.01126718
39BRSK21.01030164
40MAPKAPK30.99567145
41DYRK20.97253120
42NME10.95077836
43TEC0.94064673
44BCR0.92386296
45PRKCE0.90394546
46EIF2AK30.88711127
47MKNK20.88678469
48PDK10.88665617
49NLK0.88118341
50PASK0.87121295
51DYRK30.86998137
52TIE10.84871813
53CDK190.84073539
54KIT0.79826742
55CSNK1G10.78559676
56CSNK1G20.76526896
57TYRO30.74056432
58CSNK1G30.72915664
59PTK60.70750773
60BCKDK0.70517028
61IKBKB0.67320291
62NTRK30.65913441
63IRAK10.65721062
64TGFBR10.64984545
65EPHA20.63467814
66WEE10.63379817
67PHKG20.63186081
68PHKG10.63186081
69LMTK20.60883824
70ITK0.60203338
71TNK20.60095299
72STK30.59978212
73CAMK1G0.59714875
74STK38L0.58760862
75CSNK1A1L0.56859590
76ERBB30.54205445
77PDPK10.51057915
78VRK20.49273436
79DYRK1A0.48463620
80FGFR20.45999367
81PINK10.45212358
82PRKCG0.42824913
83RPS6KA50.42605253
84PKN10.42406164
85GRK10.42084227
86PRKAA20.41723238
87CHEK20.41453498
88TTK0.40744370
89MST40.38601762
90CSNK1A10.38328244
91EEF2K0.38148617
92MAP2K60.36179746
93EPHA40.35768419
94SYK0.35752460
95CSNK1D0.35056717
96PAK20.35052427
97NTRK20.34080358
98PAK10.33736977
99ERBB20.32708763
100MST1R0.32019475
101SIK20.31525612
102SGK20.31148379
103PAK40.30705104
104FLT30.30433225
105OBSCN0.30260063
106IGF1R0.29677161
107CHUK0.28909864
108MTOR0.28805732
109CHEK10.28305355
110MAPKAPK50.25967162
111CDK30.25140151
112PRKAA10.24389838
113IRAK20.23436178
114ATM0.23410979
115FRK0.23045851
116CAMKK10.22301141
117MUSK0.20328621
118PRKG20.20258506
119RPS6KB10.19881643
120STK160.18762066
121BMPR1B0.17433616
122PLK10.16297576
123MET0.14495957
124ATR0.12851203
125PRKCZ0.11069680
126INSRR0.10902899
127NEK60.10196274
128PRKCQ0.09697285
129BRAF0.08080889
130NTRK10.07975049
131CDC70.07213817
132PRKG10.07100960
133PRKCI0.07021533
134MAP2K20.06565296
135PIK3CG0.06467205
136TESK20.06409960
137CSNK2A10.05698910
138GSK3A0.05476806
139PTK20.05442189
140EPHB10.05397631
141FER0.04911115
142CAMK2A0.04704383
143MYLK0.04512420
144PRKACA0.04426402
145PRKACG0.04416518
146PRKCA0.03798606
147GSK3B0.03710195
148STK100.03641075
149PRKDC0.03609316
150RIPK40.03101143
151VRK10.02890306
152STK110.02642862
153MARK20.02553684
154PAK60.02417135
155RIPK10.02013292
156CAMK10.01956041
157RPS6KA10.01415546
158PRKACB0.01314878
159ARAF0.01145188
160MELK0.00697630
161PLK40.00509609
162PRKCB-0.0047309
163TRIB3-0.0045975
164CDK12-0.0037345

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.95237988
2Vitamin B6 metabolism_Homo sapiens_hsa007503.61132952
3Pyruvate metabolism_Homo sapiens_hsa006203.45370148
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.40333410
5Fatty acid biosynthesis_Homo sapiens_hsa000613.35204896
6Propanoate metabolism_Homo sapiens_hsa006402.95531351
7Phototransduction_Homo sapiens_hsa047442.79828178
8alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.73648107
9Linoleic acid metabolism_Homo sapiens_hsa005912.65373021
10Butanoate metabolism_Homo sapiens_hsa006502.60129478
11Glucagon signaling pathway_Homo sapiens_hsa049222.55570514
12Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.40343586
13Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.25254050
14Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.24232041
15Carbohydrate digestion and absorption_Homo sapiens_hsa049732.23746140
16Oxidative phosphorylation_Homo sapiens_hsa001902.21487721
17Nitrogen metabolism_Homo sapiens_hsa009102.18846766
18Dorso-ventral axis formation_Homo sapiens_hsa043202.15397749
19Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.10302301
20Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.09304367
21Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.97412732
22Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.93927551
23Nicotine addiction_Homo sapiens_hsa050331.91661097
24Glycerolipid metabolism_Homo sapiens_hsa005611.88818451
25Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.88262257
26Huntingtons disease_Homo sapiens_hsa050161.85209291
27Caffeine metabolism_Homo sapiens_hsa002321.80183741
28PPAR signaling pathway_Homo sapiens_hsa033201.79484271
29Fructose and mannose metabolism_Homo sapiens_hsa000511.76036439
30Amphetamine addiction_Homo sapiens_hsa050311.75959598
31Olfactory transduction_Homo sapiens_hsa047401.73354602
32Selenocompound metabolism_Homo sapiens_hsa004501.71520887
33Basal transcription factors_Homo sapiens_hsa030221.69998442
34Primary bile acid biosynthesis_Homo sapiens_hsa001201.67745754
35Glycerophospholipid metabolism_Homo sapiens_hsa005641.66042231
36Mineral absorption_Homo sapiens_hsa049781.65969465
37Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.65091932
38Homologous recombination_Homo sapiens_hsa034401.64588257
39Protein export_Homo sapiens_hsa030601.63851786
40Parkinsons disease_Homo sapiens_hsa050121.63467163
41Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.61721708
42Tryptophan metabolism_Homo sapiens_hsa003801.59854356
43Glycosaminoglycan degradation_Homo sapiens_hsa005311.53490290
44RNA polymerase_Homo sapiens_hsa030201.51496330
45Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.49820073
46Oocyte meiosis_Homo sapiens_hsa041141.49031272
47Pentose phosphate pathway_Homo sapiens_hsa000301.40801538
48Cardiac muscle contraction_Homo sapiens_hsa042601.38873683
49Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.37126250
50Ether lipid metabolism_Homo sapiens_hsa005651.37012375
51Steroid hormone biosynthesis_Homo sapiens_hsa001401.34901366
52Peroxisome_Homo sapiens_hsa041461.33500779
53Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.30904507
54Insulin secretion_Homo sapiens_hsa049111.29476754
55Regulation of autophagy_Homo sapiens_hsa041401.27731657
56Antigen processing and presentation_Homo sapiens_hsa046121.24924941
57Fat digestion and absorption_Homo sapiens_hsa049751.23723879
58Carbon metabolism_Homo sapiens_hsa012001.22293550
59Intestinal immune network for IgA production_Homo sapiens_hsa046721.18383101
60Fanconi anemia pathway_Homo sapiens_hsa034601.15532816
61Collecting duct acid secretion_Homo sapiens_hsa049661.15429626
62Fatty acid metabolism_Homo sapiens_hsa012121.14357701
63Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.13254451
64Primary immunodeficiency_Homo sapiens_hsa053401.13087315
65Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.11464530
66Renin secretion_Homo sapiens_hsa049241.11149967
67Fatty acid degradation_Homo sapiens_hsa000711.10698047
68Morphine addiction_Homo sapiens_hsa050321.08980612
69beta-Alanine metabolism_Homo sapiens_hsa004101.08244159
70Arachidonic acid metabolism_Homo sapiens_hsa005901.05622883
71Purine metabolism_Homo sapiens_hsa002301.03953164
72Hedgehog signaling pathway_Homo sapiens_hsa043401.03771623
73Type I diabetes mellitus_Homo sapiens_hsa049401.03724520
74Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.03125503
75Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.01196230
76Alzheimers disease_Homo sapiens_hsa050100.99166424
77Cysteine and methionine metabolism_Homo sapiens_hsa002700.98509190
78Glutathione metabolism_Homo sapiens_hsa004800.94581617
79Thyroid hormone synthesis_Homo sapiens_hsa049180.93797641
80Serotonergic synapse_Homo sapiens_hsa047260.92311975
81Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.90867307
82Histidine metabolism_Homo sapiens_hsa003400.89796116
83Taste transduction_Homo sapiens_hsa047420.88924926
84Estrogen signaling pathway_Homo sapiens_hsa049150.88831446
85Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.88744648
86Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.87079212
87RNA degradation_Homo sapiens_hsa030180.86901188
88Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.84226530
89Allograft rejection_Homo sapiens_hsa053300.84023187
90Gastric acid secretion_Homo sapiens_hsa049710.83025443
91One carbon pool by folate_Homo sapiens_hsa006700.82853897
92Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.82158935
93Synaptic vesicle cycle_Homo sapiens_hsa047210.80433339
94Autoimmune thyroid disease_Homo sapiens_hsa053200.79403931
95Pentose and glucuronate interconversions_Homo sapiens_hsa000400.76801157
96Protein digestion and absorption_Homo sapiens_hsa049740.75859221
97GABAergic synapse_Homo sapiens_hsa047270.75370843
98Graft-versus-host disease_Homo sapiens_hsa053320.74193991
99Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.73496154
100cGMP-PKG signaling pathway_Homo sapiens_hsa040220.73203722
101mRNA surveillance pathway_Homo sapiens_hsa030150.73090649
102Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.71756355
103Glutamatergic synapse_Homo sapiens_hsa047240.71657719
104RNA transport_Homo sapiens_hsa030130.71577270
105Proteasome_Homo sapiens_hsa030500.71412624
106Renin-angiotensin system_Homo sapiens_hsa046140.69891422
107SNARE interactions in vesicular transport_Homo sapiens_hsa041300.69583972
108Circadian rhythm_Homo sapiens_hsa047100.68865075
109Asthma_Homo sapiens_hsa053100.68777297
110Bile secretion_Homo sapiens_hsa049760.68669862
111Pancreatic secretion_Homo sapiens_hsa049720.66625715
112Adipocytokine signaling pathway_Homo sapiens_hsa049200.65842836
113Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.64796832
114Maturity onset diabetes of the young_Homo sapiens_hsa049500.64471936
115Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.63165955
116Calcium signaling pathway_Homo sapiens_hsa040200.60375045
117Long-term potentiation_Homo sapiens_hsa047200.59814977
118AMPK signaling pathway_Homo sapiens_hsa041520.59695636
119Tyrosine metabolism_Homo sapiens_hsa003500.57232074
120Cocaine addiction_Homo sapiens_hsa050300.56531972
121Salivary secretion_Homo sapiens_hsa049700.55863254
122ABC transporters_Homo sapiens_hsa020100.55777293
123Vascular smooth muscle contraction_Homo sapiens_hsa042700.54254479
124Endocytosis_Homo sapiens_hsa041440.52955264
125Circadian entrainment_Homo sapiens_hsa047130.52617244
126Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.52608546
127Inositol phosphate metabolism_Homo sapiens_hsa005620.51137995
128Biosynthesis of amino acids_Homo sapiens_hsa012300.50083011
129Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.48485751
130Sulfur relay system_Homo sapiens_hsa041220.47684288
131Phosphatidylinositol signaling system_Homo sapiens_hsa040700.43802215
132Sphingolipid metabolism_Homo sapiens_hsa006000.43660519
133Non-homologous end-joining_Homo sapiens_hsa034500.43578743
134Metabolic pathways_Homo sapiens_hsa011000.42726628
135N-Glycan biosynthesis_Homo sapiens_hsa005100.42068890
136Chemical carcinogenesis_Homo sapiens_hsa052040.40765457
137Thyroid hormone signaling pathway_Homo sapiens_hsa049190.37326404
138Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.37123101
139Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.35853522
140Tight junction_Homo sapiens_hsa045300.35607611
141Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.34435954
142Pyrimidine metabolism_Homo sapiens_hsa002400.33859934
143Wnt signaling pathway_Homo sapiens_hsa043100.33553435
144Vibrio cholerae infection_Homo sapiens_hsa051100.33422274
145Basal cell carcinoma_Homo sapiens_hsa052170.32637081
146Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.31953376
147cAMP signaling pathway_Homo sapiens_hsa040240.31862785
148Central carbon metabolism in cancer_Homo sapiens_hsa052300.31095634
149Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.29977863
150Phenylalanine metabolism_Homo sapiens_hsa003600.28661412
151Nucleotide excision repair_Homo sapiens_hsa034200.28351125
152Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.26501266
153Sulfur metabolism_Homo sapiens_hsa009200.25907968
154Legionellosis_Homo sapiens_hsa051340.25700800
155Longevity regulating pathway - mammal_Homo sapiens_hsa042110.24355448
156Ovarian steroidogenesis_Homo sapiens_hsa049130.23698855
157Retinol metabolism_Homo sapiens_hsa008300.22287471
158Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.21642044
159Aldosterone synthesis and secretion_Homo sapiens_hsa049250.20842821
160Vitamin digestion and absorption_Homo sapiens_hsa049770.19692077

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