MYBPH

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sarcoplasmic reticulum calcium ion transport (GO:0070296)9.36080792
2regulation of skeletal muscle contraction (GO:0014819)8.96091275
3actin filament-based movement (GO:0030048)8.49228664
4myoblast fusion (GO:0007520)8.27521386
5plasma membrane repair (GO:0001778)7.89290818
6response to inactivity (GO:0014854)7.70623263
7muscle cell fate commitment (GO:0042693)7.57418235
8heart contraction (GO:0060047)7.44789333
9heart process (GO:0003015)7.44789333
10syncytium formation by plasma membrane fusion (GO:0000768)7.43747622
11positive regulation of myotube differentiation (GO:0010831)7.42824072
12musculoskeletal movement (GO:0050881)7.29112920
13multicellular organismal movement (GO:0050879)7.29112920
14striated muscle atrophy (GO:0014891)7.18390865
15response to stimulus involved in regulation of muscle adaptation (GO:0014874)7.09580507
16syncytium formation (GO:0006949)6.90291540
17striated muscle contraction (GO:0006941)6.43608867
18muscle fiber development (GO:0048747)6.41262831
19negative regulation of potassium ion transmembrane transporter activity (GO:1901017)6.34071533
20muscle atrophy (GO:0014889)6.22881981
21positive regulation of skeletal muscle tissue development (GO:0048643)6.07050669
22sarcomere organization (GO:0045214)6.06476957
23skeletal muscle tissue development (GO:0007519)5.94112280
24negative regulation of nitric-oxide synthase activity (GO:0051001)5.88321036
25muscle contraction (GO:0006936)5.84607718
26response to muscle activity (GO:0014850)5.61805612
27muscle cell cellular homeostasis (GO:0046716)5.61411419
28positive regulation of myoblast differentiation (GO:0045663)5.58848821
29skeletal muscle adaptation (GO:0043501)5.56700063
30regulation of syncytium formation by plasma membrane fusion (GO:0060142)5.43764896
31muscle organ development (GO:0007517)5.32614579
32muscle system process (GO:0003012)5.24696410
33regulation of skeletal muscle cell differentiation (GO:2001014)5.24471494
34plasma membrane fusion (GO:0045026)5.20750773
35muscle structure development (GO:0061061)5.20027177
36regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)5.06013992
37membrane raft organization (GO:0031579)4.93402781
38negative regulation of potassium ion transmembrane transport (GO:1901380)4.85780450
39neuromuscular synaptic transmission (GO:0007274)4.79601608
40negative regulation of muscle hypertrophy (GO:0014741)4.78941747
41striated muscle adaptation (GO:0014888)4.71596656
42peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)4.67092859
43striated muscle cell development (GO:0055002)4.65565679
44positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)4.64437947
45muscle tissue morphogenesis (GO:0060415)4.60400715
46actomyosin structure organization (GO:0031032)4.43924694
47regulation of cell communication by electrical coupling (GO:0010649)4.43889242
48regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)4.43858361
49actin filament depolymerization (GO:0030042)4.40201549
50myotube differentiation (GO:0014902)4.35028625
51positive regulation of mitochondrial calcium ion concentration (GO:0051561)4.34545919
52cardiac muscle tissue morphogenesis (GO:0055008)4.29791951
53myofibril assembly (GO:0030239)4.28975682
54neuromuscular junction development (GO:0007528)4.14749561
55muscle cell development (GO:0055001)4.09367295
56synaptic transmission, cholinergic (GO:0007271)4.08949131
57regulation of alkaline phosphatase activity (GO:0010692)4.06321993
58positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.97865125
59regulation of integrin-mediated signaling pathway (GO:2001044)3.96790956
60striated muscle tissue development (GO:0014706)3.96432547
61regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.94309909
62muscle adaptation (GO:0043500)3.75747255
63negative regulation of monooxygenase activity (GO:0032769)3.73696452
64skeletal muscle tissue regeneration (GO:0043403)3.72321713
65regulation of myoblast differentiation (GO:0045661)3.65563206
66regulation of myotube differentiation (GO:0010830)3.55094709
67negative regulation of cardiac muscle hypertrophy (GO:0010614)3.54259685
68response to lithium ion (GO:0010226)3.53688230
69negative regulation of cell size (GO:0045792)3.48928807
70muscle tissue development (GO:0060537)3.48155219
71membrane assembly (GO:0071709)3.39611240
72cardiac muscle contraction (GO:0060048)3.37619256
73positive regulation of protein homodimerization activity (GO:0090073)3.36485004
74negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.34938907
75regulation of p38MAPK cascade (GO:1900744)3.34462381
76negative regulation of heart growth (GO:0061117)3.32967461
77negative regulation of cardiac muscle tissue growth (GO:0055022)3.32967461
78negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.31072050
79positive regulation of striated muscle cell differentiation (GO:0051155)3.29848661
80response to gravity (GO:0009629)3.26016834
81bundle of His cell to Purkinje myocyte communication (GO:0086069)3.23571576
82positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc3.22681970
83creatine metabolic process (GO:0006600)3.22296440
84positive regulation of actin filament depolymerization (GO:0030836)3.20968731
85response to caffeine (GO:0031000)3.20275279
86cardiac cell development (GO:0055006)3.19464349
87regulation of cardiac muscle cell differentiation (GO:2000725)3.18116765
88glycogen catabolic process (GO:0005980)3.17784770
89heterotypic cell-cell adhesion (GO:0034113)3.12329176
90positive regulation of astrocyte differentiation (GO:0048711)3.10711238
91* regulation of muscle system process (GO:0090257)3.09853882
92regulation of calcium ion transmembrane transporter activity (GO:1901019)3.08350172
93regulation of calcium ion transmembrane transport (GO:1903169)3.08350172
94regulation of potassium ion transmembrane transporter activity (GO:1901016)3.06100562
95neuronal action potential (GO:0019228)3.02282945
96positive regulation of muscle cell differentiation (GO:0051149)3.01530528
97endodermal cell differentiation (GO:0035987)3.00226846
98regulation of skeletal muscle tissue development (GO:0048641)2.99188832
99regulation of action potential (GO:0098900)2.99017687
100glucan catabolic process (GO:0009251)2.98163704
101* regulation of muscle contraction (GO:0006937)2.96223840
102regulation of membrane repolarization (GO:0060306)2.94506399
103glucan biosynthetic process (GO:0009250)2.93803073
104glycogen biosynthetic process (GO:0005978)2.93803073
105regulation of skeletal muscle fiber development (GO:0048742)2.93394033
106regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.90165455
107cellular response to estradiol stimulus (GO:0071392)2.87605243
108regulation of sarcomere organization (GO:0060297)2.86734451
109cardiac myofibril assembly (GO:0055003)2.85847524
110mRNA transcription from RNA polymerase II promoter (GO:0042789)2.82987728
111skeletal muscle cell differentiation (GO:0035914)2.76817795
112membrane tubulation (GO:0097320)2.75203858
113* regulation of striated muscle contraction (GO:0006942)2.73310452
114cellular polysaccharide catabolic process (GO:0044247)2.69368035
115mRNA transcription (GO:0009299)2.68226696
116negative regulation of protein localization to cell surface (GO:2000009)2.67600818
117polysaccharide catabolic process (GO:0000272)2.57823818
118actin filament-based process (GO:0030029)2.50606356
119regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.48812159
120negative regulation of potassium ion transport (GO:0043267)2.42852242
121response to activity (GO:0014823)2.42665707
122positive regulation of p38MAPK cascade (GO:1900745)2.42616963
123mitochondrial calcium ion homeostasis (GO:0051560)2.41079685
124cardiac muscle cell development (GO:0055013)2.38025076
125muscle filament sliding (GO:0030049)13.6324055
126actin-myosin filament sliding (GO:0033275)13.6324055
127skeletal muscle contraction (GO:0003009)12.3919777
128skeletal muscle fiber development (GO:0048741)12.2437548
129actin-mediated cell contraction (GO:0070252)11.1994864
130myotube cell development (GO:0014904)10.3599606

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GATA1_22025678_ChIP-Seq_K562_Human6.86222348
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.90717080
3ESR1_20079471_ChIP-ChIP_T-47D_Human3.90919586
4RARG_19884340_ChIP-ChIP_MEFs_Mouse3.40774862
5TP63_17297297_ChIP-ChIP_HaCaT_Human3.36560253
6ZNF652_21678463_ChIP-ChIP_ZR75-1_Human3.32118774
7SMAD_19615063_ChIP-ChIP_OVARY_Human3.28907919
8TRIM28_21343339_ChIP-Seq_HEK293_Human2.77562310
9BP1_19119308_ChIP-ChIP_Hs578T_Human2.71107960
10THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.47768327
11PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.43241478
12ESR1_21235772_ChIP-Seq_MCF-7_Human2.30475228
13PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.29624908
14RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.27271193
15TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.25496075
16BRD4_25478319_ChIP-Seq_HGPS_Human2.20034439
17ESR2_21235772_ChIP-Seq_MCF-7_Human2.17774905
18TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.16261205
19CLOCK_20551151_ChIP-Seq_293T_Human2.09490670
20ZNF263_19887448_ChIP-Seq_K562_Human2.02810263
21TBX20_22328084_ChIP-Seq_HEART_Mouse1.97859154
22TBX20_22080862_ChIP-Seq_HEART_Mouse1.97859154
23* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.95256081
24TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.82877702
25WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.75566118
26PCGF2_27294783_Chip-Seq_NPCs_Mouse1.73121559
27RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.70774168
28TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.70308122
29EZH2_27294783_Chip-Seq_ESCs_Mouse1.70180763
30* CRX_20693478_ChIP-Seq_RETINA_Mouse1.69717528
31* SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.69596665
32* LXR_22292898_ChIP-Seq_THP-1_Human1.66850876
33NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.66349966
34* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.66230050
35NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.66096792
36MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.64209127
37WT1_19549856_ChIP-ChIP_CCG9911_Human1.62885058
38SMC1_22415368_ChIP-Seq_MEFs_Mouse1.58521511
39SUZ12_27294783_Chip-Seq_NPCs_Mouse1.51952207
40CDX2_19796622_ChIP-Seq_MESCs_Mouse1.49744307
41SRF_21415370_ChIP-Seq_HL-1_Mouse1.48866763
42KDM2B_26808549_Chip-Seq_DND41_Human1.47695308
43PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.47551255
44EZH2_27294783_Chip-Seq_NPCs_Mouse1.45817998
45TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.43911286
46CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.43737229
47EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.43493519
48ELK3_25401928_ChIP-Seq_HUVEC_Human1.43322651
49SALL1_21062744_ChIP-ChIP_HESCs_Human1.41874470
50GATA2_21666600_ChIP-Seq_HMVEC_Human1.41079466
51KDM2B_26808549_Chip-Seq_SUP-B15_Human1.40672244
52SMC3_22415368_ChIP-Seq_MEFs_Mouse1.38949184
53* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.38684280
54* NFE2_27457419_Chip-Seq_LIVER_Mouse1.37445036
55SUZ12_27294783_Chip-Seq_ESCs_Mouse1.36297756
56* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.35834430
57SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.34235583
58EP300_21415370_ChIP-Seq_HL-1_Mouse1.33192645
59BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.33126893
60ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.31183737
61MTF2_20144788_ChIP-Seq_MESCs_Mouse1.31141215
62GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.30435346
63* ATF3_27146783_Chip-Seq_COLON_Human1.29774094
64RACK7_27058665_Chip-Seq_MCF-7_Human1.29654236
65TP53_20018659_ChIP-ChIP_R1E_Mouse1.29331842
66GATA4_21415370_ChIP-Seq_HL-1_Mouse1.28716467
67SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.28382947
68CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.28265733
69EZH2_22144423_ChIP-Seq_EOC_Human1.26873957
70* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.25741668
71* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.25466188
72RAD21_21589869_ChIP-Seq_MESCs_Mouse1.25332380
73CTCF_21964334_ChIP-Seq_BJAB-B_Human1.25309973
74* STAT3_18555785_Chip-Seq_ESCs_Mouse1.25045543
75* CTCF_27219007_Chip-Seq_Bcells_Human1.23877621
76CTCF_21964334_Chip-Seq_Bcells_Human1.23164439
77KDM2B_26808549_Chip-Seq_K562_Human1.21237057
78RNF2_18974828_ChIP-Seq_MESCs_Mouse1.21040324
79EZH2_18974828_ChIP-Seq_MESCs_Mouse1.21040324
80CJUN_26792858_Chip-Seq_BT549_Human1.20602342
81DNAJC2_21179169_ChIP-ChIP_NT2_Human1.18893551
82ERG_21242973_ChIP-ChIP_JURKAT_Human1.18866102
83* ZFX_18555785_Chip-Seq_ESCs_Mouse1.18611122
84TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.17784283
85* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.17704490
86* SOX2_18555785_Chip-Seq_ESCs_Mouse1.17348910
87TP53_22127205_ChIP-Seq_IMR90_Human1.16885319
88ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.16642539
89PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.16066697
90LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.15768764
91MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.15517570
92EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.15492357
93STAT6_21828071_ChIP-Seq_BEAS2B_Human1.14994612
94* P53_22387025_ChIP-Seq_ESCs_Mouse1.14556194
95KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.14539888
96* PU1_27457419_Chip-Seq_LIVER_Mouse1.12245785
97PPARA_22158963_ChIP-Seq_LIVER_Mouse1.11359676
98ELK1_22589737_ChIP-Seq_MCF10A_Human1.10804911
99NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.10470654
100NFI_21473784_ChIP-Seq_ESCs_Mouse1.09567610
101ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.07736026
102* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.06841753
103* SMAD1_18555785_Chip-Seq_ESCs_Mouse1.06800293
104* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.05248290
105TP53_18474530_ChIP-ChIP_U2OS_Human1.04258350
106OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.03844855
107TP53_23651856_ChIP-Seq_MEFs_Mouse1.03063831
108CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.00710324
109TP53_16413492_ChIP-PET_HCT116_Human1.00247242
110RUNX1_27514584_Chip-Seq_MCF-7_Human0.99891544
111RARB_27405468_Chip-Seq_BRAIN_Mouse0.99575963
112CTCF_27219007_Chip-Seq_ERYTHROID_Human0.98959163
113SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.98936665
114TCF7_22412390_ChIP-Seq_EML_Mouse0.98900542
115SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.98827608
116* SA1_27219007_Chip-Seq_Bcells_Human0.98531643
117CSB_26484114_Chip-Seq_FIBROBLAST_Human0.97955829
118CBP_20019798_ChIP-Seq_JUKART_Human0.97392086
119IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.97392086
120* OCT4_21477851_ChIP-Seq_ESCs_Mouse0.97160300
121CREB1_26743006_Chip-Seq_LNCaP_Human0.96352764
122TCF3_18692474_ChIP-Seq_MEFs_Mouse0.95549834
123FOXH1_21741376_ChIP-Seq_ESCs_Human0.95339394
124SOX9_24532713_ChIP-Seq_HFSC_Mouse0.94335883
125PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.94283478
126KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.94169805
127DROSHA_22980978_ChIP-Seq_HELA_Human0.92675847
128* PPAR_26484153_Chip-Seq_NCI-H1993_Human0.92582434
129KDM2B_26808549_Chip-Seq_REH_Human0.92506407
130* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.92086315
131* OCT4_18555785_Chip-Seq_ESCs_Mouse0.91822787
132ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.90944131
133NRF2_20460467_ChIP-Seq_MEFs_Mouse0.90940862
134NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.90940862
135GATA1_19941826_ChIP-Seq_K562_Human0.90451045
136NFIB_24661679_ChIP-Seq_LUNG_Mouse0.90231652
137SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.89384225
138TBX5_21415370_ChIP-Seq_HL-1_Mouse0.87454690
139OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.86997398
140ZNF274_21170338_ChIP-Seq_K562_Hela0.86938687
141GABP_17652178_ChIP-ChIP_JURKAT_Human0.86242651
142NR3C1_23031785_ChIP-Seq_PC12_Mouse0.86188567
143SA1_22415368_ChIP-Seq_MEFs_Mouse0.86161285
144HIF1A_21447827_ChIP-Seq_MCF-7_Human0.85877795
145P63_26484246_Chip-Seq_KERATINOCYTES_Human0.84842312
146NR3C1_21868756_ChIP-Seq_MCF10A_Human0.84836209
147* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.84198584
148NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.84161723
149* CTCF_18555785_Chip-Seq_ESCs_Mouse0.83133486
150KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.83012076
151EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.82158740
152* KLF4_18555785_Chip-Seq_ESCs_Mouse0.81876849
153LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.80744840
154HTT_18923047_ChIP-ChIP_STHdh_Human0.80489048
155EOMES_21245162_ChIP-Seq_HESCs_Human0.80016246
156POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.78271612
157* SUZ12_18555785_Chip-Seq_ESCs_Mouse0.77796083
158* P300_18555785_Chip-Seq_ESCs_Mouse0.74472725
159SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.74194166

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000749_muscle_degeneration7.30551357
2MP0000751_myopathy6.72814138
3MP0004145_abnormal_muscle_electrophysio6.20998411
4MP0000747_muscle_weakness4.74653425
5MP0002106_abnormal_muscle_physiology4.44135456
6MP0000733_abnormal_muscle_development4.32714063
7MP0000750_abnormal_muscle_regeneration4.13804632
8MP0000759_abnormal_skeletal_muscle4.02329984
9MP0004270_analgesia3.96124368
10MP0002837_dystrophic_cardiac_calcinosis3.72506178
11MP0004087_abnormal_muscle_fiber3.72446884
12MP0005369_muscle_phenotype3.65194142
13MP0002269_muscular_atrophy3.53113261
14MP0004036_abnormal_muscle_relaxation2.81553964
15MP0004233_abnormal_muscle_weight2.58768422
16MP0003646_muscle_fatigue2.53808195
17MP0005620_abnormal_muscle_contractility2.30505613
18MP0002108_abnormal_muscle_morphology2.20526285
19MP0004084_abnormal_cardiac_muscle2.14710885
20MP0002971_abnormal_brown_adipose2.07528642
21MP0005330_cardiomyopathy1.77752737
22MP0003950_abnormal_plasma_membrane1.53576963
23MP0004130_abnormal_muscle_cell1.49536118
24MP0004215_abnormal_myocardial_fiber1.39356814
25MP0008438_abnormal_cutaneous_collagen1.38339831
26MP0001542_abnormal_bone_strength1.38111284
27MP0005623_abnormal_meninges_morphology1.37187333
28MP0001958_emphysema1.30500712
29MP0004883_abnormal_blood_vessel1.25182382
30MP0002249_abnormal_larynx_morphology1.24407246
31MP0010630_abnormal_cardiac_muscle1.20947832
32MP0003011_delayed_dark_adaptation1.20211103
33MP0009780_abnormal_chondrocyte_physiolo1.17969566
34MP0002972_abnormal_cardiac_muscle1.13703838
35MP0002933_joint_inflammation1.13516918
36MP0002332_abnormal_exercise_endurance1.12754160
37MP0002734_abnormal_mechanical_nocicepti1.08544267
38MP0001299_abnormal_eye_distance/1.07385877
39MP0005275_abnormal_skin_tensile1.03467044
40MP0005595_abnormal_vascular_smooth1.03133690
41MP0002127_abnormal_cardiovascular_syste0.94355827
42MP0004858_abnormal_nervous_system0.93222166
43MP0004484_altered_response_of0.92425113
44MP0002234_abnormal_pharynx_morphology0.92074308
45MP0003705_abnormal_hypodermis_morpholog0.89794520
46MP0005451_abnormal_body_composition0.88861968
47MP0004134_abnormal_chest_morphology0.86892863
48MP0003941_abnormal_skin_development0.85943671
49MP0009250_abnormal_appendicular_skeleto0.84517479
50MP0001440_abnormal_grooming_behavior0.83886359
51MP0010030_abnormal_orbit_morphology0.82552013
52MP0000767_abnormal_smooth_muscle0.81571410
53MP0003045_fibrosis0.79868222
54MP0000372_irregular_coat_pigmentation0.77981339
55MP0004185_abnormal_adipocyte_glucose0.76670169
56MP0008569_lethality_at_weaning0.76625154
57MP0005503_abnormal_tendon_morphology0.75263134
58MP0001986_abnormal_taste_sensitivity0.75045034
59MP0005165_increased_susceptibility_to0.74762182
60MP0008775_abnormal_heart_ventricle0.73621723
61MP0002114_abnormal_axial_skeleton0.73025208
62MP0003191_abnormal_cellular_cholesterol0.72749972
63MP0005360_urolithiasis0.71868243
64MP0005266_abnormal_metabolism0.71374452
65MP0000013_abnormal_adipose_tissue0.70600840
66MP0003566_abnormal_cell_adhesion0.69593863
67MP0000230_abnormal_systemic_arterial0.66357302
68MP0003879_abnormal_hair_cell0.65003399
69MP0006036_abnormal_mitochondrial_physio0.63629065
70MP0002184_abnormal_innervation0.63583599
71MP0001943_abnormal_respiration0.62907201
72MP0006054_spinal_hemorrhage0.62311513
73MP0003137_abnormal_impulse_conducting0.62149176
74MP0000762_abnormal_tongue_morphology0.59192434
75MP0003279_aneurysm0.59038252
76MP0002736_abnormal_nociception_after0.57208284
77MP0003948_abnormal_gas_homeostasis0.57202961
78MP0003091_abnormal_cell_migration0.56747501
79MP0005023_abnormal_wound_healing0.56726005
80MP0003385_abnormal_body_wall0.56548584
81MP0005164_abnormal_response_to0.56167500
82MP0006138_congestive_heart_failure0.54997011
83MP0005375_adipose_tissue_phenotype0.54309800
84MP0005385_cardiovascular_system_phenoty0.53039640
85MP0001544_abnormal_cardiovascular_syste0.53039640
86MP0005666_abnormal_adipose_tissue0.52641051
87MP0009384_cardiac_valve_regurgitation0.51519860
88MP0001661_extended_life_span0.50751435
89MP0000955_abnormal_spinal_cord0.50576262
90MP0004510_myositis0.50017769
91MP0002295_abnormal_pulmonary_circulatio0.47465547
92MP0008789_abnormal_olfactory_epithelium0.46343413
93MP0001915_intracranial_hemorrhage0.46207026
94MP0004272_abnormal_basement_membrane0.46015322
95MP0000003_abnormal_adipose_tissue0.45834225
96MP0005171_absent_coat_pigmentation0.45388235
97MP0000678_abnormal_parathyroid_gland0.45237429
98MP0005452_abnormal_adipose_tissue0.44464253
99MP0002168_other_aberrant_phenotype0.43305274
100MP0005319_abnormal_enzyme/_coenzyme0.42813279
101MP0005388_respiratory_system_phenotype0.42781491
102MP0002133_abnormal_respiratory_system0.42781491
103MP0003959_abnormal_lean_body0.42328979
104MP0003221_abnormal_cardiomyocyte_apopto0.41924186
105MP0002132_abnormal_respiratory_system0.41461377
106MP0001346_abnormal_lacrimal_gland0.40979313
107MP0002896_abnormal_bone_mineralization0.40898034
108MP0001243_abnormal_dermal_layer0.40409482
109MP0002877_abnormal_melanocyte_morpholog0.38709328
110MP0003755_abnormal_palate_morphology0.38265538
111MP0005501_abnormal_skin_physiology0.38005073
112MP0000249_abnormal_blood_vessel0.37381074
113MP0000266_abnormal_heart_morphology0.36587118
114MP0002282_abnormal_trachea_morphology0.36065886
115MP0005508_abnormal_skeleton_morphology0.35691576
116MP0005248_abnormal_Harderian_gland0.35684470
117MP0004197_abnormal_fetal_growth/weight/0.34038191
118MP0005058_abnormal_lysosome_morphology0.33472296
119MP0002932_abnormal_joint_morphology0.32647184
120MP0002128_abnormal_blood_circulation0.32620262
121MP0008961_abnormal_basal_metabolism0.31559887
122MP0002066_abnormal_motor_capabilities/c0.31065926
123MP0002796_impaired_skin_barrier0.30104846
124MP0005670_abnormal_white_adipose0.30097755
125MP0002081_perinatal_lethality0.30091085
126MP0004085_abnormal_heartbeat0.29429288
127MP0003828_pulmonary_edema0.28139852
128MP0003806_abnormal_nucleotide_metabolis0.28117429
129MP0001784_abnormal_fluid_regulation0.26924377
130MP0001849_ear_inflammation0.26893962
131MP0003115_abnormal_respiratory_system0.25992371
132MP0002089_abnormal_postnatal_growth/wei0.25777304
133MP0005334_abnormal_fat_pad0.25089061

Predicted human phenotypes

RankGene SetZ-score
1Fetal akinesia sequence (HP:0001989)8.51675364
2Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)8.28425828
3Nemaline bodies (HP:0003798)8.11549887
4Popliteal pterygium (HP:0009756)7.87221503
5Muscle fiber inclusion bodies (HP:0100299)7.82231804
6Type 1 muscle fiber predominance (HP:0003803)7.19555865
7Aplasia of the musculature (HP:0100854)7.15982674
8Amniotic constriction ring (HP:0009775)6.91985096
9Abnormality of placental membranes (HP:0011409)6.91985096
10Malignant hyperthermia (HP:0002047)6.39275738
11Distal arthrogryposis (HP:0005684)6.39042024
12Round ear (HP:0100830)6.07222787
13Akinesia (HP:0002304)5.90631417
14Ulnar deviation of the wrist (HP:0003049)5.86972661
15Myopathic facies (HP:0002058)5.57157249
16Calcaneovalgus deformity (HP:0001848)5.10116679
17Type 2 muscle fiber atrophy (HP:0003554)4.77172928
18Deformed tarsal bones (HP:0008119)4.63932080
19Fatigable weakness (HP:0003473)4.61003611
20Abnormality of the neuromuscular junction (HP:0003398)4.61003611
21Weak cry (HP:0001612)4.53423606
22Abnormality of skeletal muscle fiber size (HP:0012084)4.38381266
23Absent phalangeal crease (HP:0006109)4.38096440
24Muscle fiber atrophy (HP:0100295)4.32160260
25Aplasia/Hypoplasia involving the musculature (HP:0001460)4.23253923
26Bulbar palsy (HP:0001283)4.05844358
27Pterygium (HP:0001059)4.02802826
28Thin ribs (HP:0000883)3.94016174
29Hypoplastic heart (HP:0001961)3.87610291
30Exercise-induced myalgia (HP:0003738)3.86922716
31Long clavicles (HP:0000890)3.77538517
32Difficulty running (HP:0009046)3.68748949
33EMG: myopathic abnormalities (HP:0003458)3.68694654
34Gowers sign (HP:0003391)3.68551988
35Abnormal finger flexion creases (HP:0006143)3.66028941
36Muscle fiber splitting (HP:0003555)3.60592940
37Increased variability in muscle fiber diameter (HP:0003557)3.46387784
38Slender build (HP:0001533)3.40012192
39Mildly elevated creatine phosphokinase (HP:0008180)3.38922523
40Abnormality of the calf musculature (HP:0001430)3.35319063
41Muscle hypertrophy of the lower extremities (HP:0008968)3.34291890
42Centrally nucleated skeletal muscle fibers (HP:0003687)3.33958221
43Calf muscle hypertrophy (HP:0008981)3.31919293
44Hyporeflexia of lower limbs (HP:0002600)3.25003331
45Difficulty climbing stairs (HP:0003551)3.24262525
46Exercise-induced muscle cramps (HP:0003710)3.21262433
47Distal lower limb muscle weakness (HP:0009053)3.21206561
48Cystic hygroma (HP:0000476)3.18417471
49Abnormality of the calcaneus (HP:0008364)3.14666742
50Generalized muscle weakness (HP:0003324)3.00174959
51Easy fatigability (HP:0003388)2.97939330
52Increased connective tissue (HP:0009025)2.96987549
53Neck muscle weakness (HP:0000467)2.95514326
54Diminished movement (HP:0002374)2.95157282
55Hip contracture (HP:0003273)2.93780395
56Asymmetric septal hypertrophy (HP:0001670)2.88152560
57Neonatal respiratory distress (HP:0002643)2.85525157
58Aortic aneurysm (HP:0004942)2.83115265
59Frequent falls (HP:0002359)2.80234777
60Depressed nasal tip (HP:0000437)2.71739608
61Abnormalities of placenta or umbilical cord (HP:0001194)2.62579280
62Symphalangism affecting the phalanges of the hand (HP:0009773)2.58799427
63Trismus (HP:0000211)2.58002159
64Abnormality of the left ventricular outflow tract (HP:0011103)2.52059484
65Subaortic stenosis (HP:0001682)2.52059484
66Decreased muscle mass (HP:0003199)2.43815945
67Areflexia of lower limbs (HP:0002522)2.42099817
68Spinal rigidity (HP:0003306)2.41307040
69Respiratory insufficiency due to muscle weakness (HP:0002747)2.38972773
70Breech presentation (HP:0001623)2.35331892
71Webbed neck (HP:0000465)2.33585051
72Scapular winging (HP:0003691)2.32481883
73Aortic dissection (HP:0002647)2.24492603
74Cerebral aneurysm (HP:0004944)2.24297823
75Distal lower limb amyotrophy (HP:0008944)2.23459424
76Arthrogryposis multiplex congenita (HP:0002804)2.23329796
77EMG: neuropathic changes (HP:0003445)2.21277200
78Metatarsus adductus (HP:0001840)2.14076140
79Poor suck (HP:0002033)2.09434369
80Rib fusion (HP:0000902)2.08904898
81Myotonia (HP:0002486)2.07297674
82Abnormal pupillary function (HP:0007686)2.05143147
83Lipoatrophy (HP:0100578)2.04050296
84Limited hip movement (HP:0008800)2.02770802
85Mask-like facies (HP:0000298)1.99529413
86Limb-girdle muscle atrophy (HP:0003797)1.95653903
87Fused cervical vertebrae (HP:0002949)1.95073743
88Hypoplastic nipples (HP:0002557)1.93460887
89Myoglobinuria (HP:0002913)1.88893880
90Facial diplegia (HP:0001349)1.84669169
91Infantile muscular hypotonia (HP:0008947)1.83592901
92Abnormality of the labia majora (HP:0012881)1.83107179
93Vertebral fusion (HP:0002948)1.81777527
94Waddling gait (HP:0002515)1.80934198
95Nonprogressive disorder (HP:0003680)1.79138667
96Vertebral clefting (HP:0008428)1.78907386
97Bundle branch block (HP:0011710)1.73676620
98Congenital hip dislocation (HP:0001374)1.71876067
99Lower limb amyotrophy (HP:0007210)1.71538491
100Chin dimple (HP:0010751)1.71411589
101Generalized amyotrophy (HP:0003700)1.70931677
102Abnormality of the shoulder girdle musculature (HP:0001435)1.69545683
103Left ventricular hypertrophy (HP:0001712)1.69352187
104Short palpebral fissure (HP:0012745)1.67755624
105Sudden death (HP:0001699)1.67188175
106Ulnar deviation of finger (HP:0009465)1.66513371
107Abnormality of the umbilical cord (HP:0010881)1.64704685
108Protrusio acetabuli (HP:0003179)1.62685801
109Short thorax (HP:0010306)1.62569519
110Tarsal synostosis (HP:0008368)1.62470368
111Rocker bottom foot (HP:0001838)1.61022269
112Delayed gross motor development (HP:0002194)1.59360583
113Ventricular arrhythmia (HP:0004308)1.57839161
114Muscle stiffness (HP:0003552)1.57513672
115Right ventricular cardiomyopathy (HP:0011663)1.54104803
116Joint contractures involving the joints of the feet (HP:0100492)1.51377619
117Flexion contracture of toe (HP:0005830)1.51377619
118Abnormality of the musculature of the pelvis (HP:0001469)1.51186760
119Abnormality of the hip-girdle musculature (HP:0001445)1.51186760
120Hypoplastic ischia (HP:0003175)1.50023310
121Shoulder girdle muscle weakness (HP:0003547)1.47871216
122Limb-girdle muscle weakness (HP:0003325)1.46264330
123Ulnar deviation of the hand or of fingers of the hand (HP:0001193)1.43145516
124Rimmed vacuoles (HP:0003805)1.41502480
125Pulmonary hypoplasia (HP:0002089)1.36543390
126Intestinal malrotation (HP:0002566)1.35952820
127Slender long bone (HP:0003100)1.32480407

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PIK3CG7.88095789
2MUSK5.51476766
3MOS4.34731028
4TRIB34.19759928
5OBSCN4.17591248
6CCNB14.16491223
7TTN3.78742129
8PHKG13.04602427
9PHKG23.04602427
10PIM22.78470723
11NME11.95110948
12MAP3K121.78105461
13MAPK121.74423711
14EEF2K1.71797797
15MAPKAPK31.62502857
16MAP3K101.61673094
17MYLK1.59748474
18PKN21.53281499
19EPHB11.48699525
20MAP2K31.44953879
21CDK81.42333421
22MAP2K11.40416041
23STK161.36063713
24ILK1.33057292
25MAP3K71.31352437
26PAK41.26840844
27ICK1.23028799
28MINK11.19080565
29DYRK1B1.14741939
30ROCK21.14049691
31CDK141.13617889
32PLK21.11466538
33TRPM71.11243949
34CDK61.11022495
35STK391.09083435
36AKT21.06189055
37CDK151.05393859
38PIK3CA1.04437913
39EIF2AK30.99372065
40CDK180.99356648
41PDK40.96983524
42PDK30.96983524
43CDK11A0.96378558
44PBK0.94495884
45NEK10.94457691
46DMPK0.93439799
47PRKD30.88287051
48DDR20.88226170
49MAP2K40.87241195
50MAP3K50.84537789
51RIPK10.82797535
52ROCK10.75704194
53PTK60.74167609
54VRK20.72653321
55LIMK10.72622237
56TGFBR20.68732164
57MAP3K130.68370123
58DAPK30.66279702
59CAMK2G0.65214692
60MELK0.64718889
61SIK10.63979965
62ARAF0.60603322
63LRRK20.60206827
64RPS6KA30.58125211
65MARK10.57734127
66MTOR0.57549480
67PRKG10.56821766
68MAPK110.56041742
69EIF2AK10.54381936
70MARK20.52168016
71MAP2K60.48464622
72PINK10.46883459
73PDGFRA0.45570012
74PDK20.45330195
75LATS20.44726028
76PRKD20.44595762
77PTK20.44395611
78FLT30.43784229
79ERN10.43136140
80CDK90.41875454
81PRKAA10.41487566
82PAK60.41387751
83PRKG20.41300855
84MAPK70.40747739
85TESK10.40154824
86PTK2B0.39377386
87PDPK10.38996252
88CDK50.38993769
89EGFR0.38457935
90CSNK1G20.37672123
91CAMK2A0.36916505
92FER0.36039524
93PRKACB0.35674285
94CAMK2B0.35624462
95EPHB20.34845578
96KSR20.34707031
97MAP3K90.33246859
98PAK20.32577801
99BCKDK0.31404567
100MAPK40.31361247
101TYRO30.30408834
102PLK30.28156241
103DAPK10.26313253
104MAPK100.25258442
105BMX0.23996744
106PRKD10.23607332
107PRKAA20.23155266
108IGF1R0.22012661
109OXSR10.21581833
110RPS6KB20.21130337
111KSR10.20782982
112EIF2AK20.19988002
113SGK10.19954881
114NEK90.19863466
115PDK10.19258106
116INSR0.18306631
117DAPK20.17627831
118WNK40.17370793
119MAPKAPK20.16606657
120RET0.16297169
121PRKACA0.15539711
122MAPK90.15358156
123MAPK80.15147398
124ERBB30.15027707
125FGFR10.14977317
126PKN10.14835035
127PRKCA0.14576342
128CAMK2D0.14392344
129CSNK2A10.14387957
130AURKB0.14110472
131NTRK10.14008466
132PAK30.13613161
133STK110.12664162
134ABL10.12114212
135CSNK1D0.12007438
136CAMK1G0.11927193
137CDK190.10279626
138PAK10.09832629
139CDC42BPA0.09796303

Predicted pathways (KEGG)

RankGene SetZ-score
1Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054105.90554392
2Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054125.59388663
3Dilated cardiomyopathy_Homo sapiens_hsa054145.48529256
4Cardiac muscle contraction_Homo sapiens_hsa042603.64033661
5Oxytocin signaling pathway_Homo sapiens_hsa049212.32124211
6Tight junction_Homo sapiens_hsa045302.20856428
7Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042612.18404371
8Focal adhesion_Homo sapiens_hsa045102.05780090
9Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.97868599
10Proteasome_Homo sapiens_hsa030501.86447416
112-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.85439909
12Viral myocarditis_Homo sapiens_hsa054161.70851939
13ECM-receptor interaction_Homo sapiens_hsa045121.64523267
14Starch and sucrose metabolism_Homo sapiens_hsa005001.57428252
15Insulin signaling pathway_Homo sapiens_hsa049101.56129184
16Glucagon signaling pathway_Homo sapiens_hsa049221.53878671
17Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.41336718
18Proteoglycans in cancer_Homo sapiens_hsa052051.37417259
19Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.37170033
20Calcium signaling pathway_Homo sapiens_hsa040201.21032785
21Vascular smooth muscle contraction_Homo sapiens_hsa042701.18255348
22Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.17668636
23Regulation of actin cytoskeleton_Homo sapiens_hsa048101.15780575
24Cyanoamino acid metabolism_Homo sapiens_hsa004601.13624681
25Biosynthesis of amino acids_Homo sapiens_hsa012301.13065081
26Insulin resistance_Homo sapiens_hsa049311.11594758
27Carbon metabolism_Homo sapiens_hsa012001.10631140
28Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.06668571
29Leukocyte transendothelial migration_Homo sapiens_hsa046701.06249612
30Amoebiasis_Homo sapiens_hsa051461.05516910
31AMPK signaling pathway_Homo sapiens_hsa041521.04592983
32MAPK signaling pathway_Homo sapiens_hsa040101.00583578
33Adipocytokine signaling pathway_Homo sapiens_hsa049200.99391443
34Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.97553682
35Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.97165741
36Fatty acid elongation_Homo sapiens_hsa000620.96619398
37GnRH signaling pathway_Homo sapiens_hsa049120.96037831
38Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.95036062
39Bladder cancer_Homo sapiens_hsa052190.94893150
40Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.93771766
41cGMP-PKG signaling pathway_Homo sapiens_hsa040220.91126124
42Central carbon metabolism in cancer_Homo sapiens_hsa052300.89817802
43HIF-1 signaling pathway_Homo sapiens_hsa040660.85047884
44Circadian rhythm_Homo sapiens_hsa047100.84512972
45Renin secretion_Homo sapiens_hsa049240.83643887
46Adherens junction_Homo sapiens_hsa045200.82097134
47Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.79123328
48VEGF signaling pathway_Homo sapiens_hsa043700.77790602
49Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.76044213
50Alzheimers disease_Homo sapiens_hsa050100.75519270
51FoxO signaling pathway_Homo sapiens_hsa040680.74715386
52Gastric acid secretion_Homo sapiens_hsa049710.73751410
53Longevity regulating pathway - mammal_Homo sapiens_hsa042110.70570683
54Folate biosynthesis_Homo sapiens_hsa007900.70393113
55Insulin secretion_Homo sapiens_hsa049110.70335182
56Glioma_Homo sapiens_hsa052140.69364680
57Chronic myeloid leukemia_Homo sapiens_hsa052200.67561000
58SNARE interactions in vesicular transport_Homo sapiens_hsa041300.66836212
59Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.66323838
60Oxidative phosphorylation_Homo sapiens_hsa001900.66011311
61Renal cell carcinoma_Homo sapiens_hsa052110.64058865
62Cholinergic synapse_Homo sapiens_hsa047250.62375678
63Platelet activation_Homo sapiens_hsa046110.60970597
64Aldosterone synthesis and secretion_Homo sapiens_hsa049250.60761564
65Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.60560530
66mTOR signaling pathway_Homo sapiens_hsa041500.60080868
67Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.59631127
68Nitrogen metabolism_Homo sapiens_hsa009100.59238035
69Galactose metabolism_Homo sapiens_hsa000520.59084615
70Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.56709900
71Selenocompound metabolism_Homo sapiens_hsa004500.55841978
72Long-term depression_Homo sapiens_hsa047300.54408996
73Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54194357
74Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.53808725
75Fructose and mannose metabolism_Homo sapiens_hsa000510.53555953
76Propanoate metabolism_Homo sapiens_hsa006400.51750764
77Pertussis_Homo sapiens_hsa051330.50930670
78Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.49608104
79Pyruvate metabolism_Homo sapiens_hsa006200.49037814
80Protein digestion and absorption_Homo sapiens_hsa049740.48742241
81Melanogenesis_Homo sapiens_hsa049160.48718507
82Arginine and proline metabolism_Homo sapiens_hsa003300.48232419
83Arginine biosynthesis_Homo sapiens_hsa002200.47996307
84Small cell lung cancer_Homo sapiens_hsa052220.47979082
85Prion diseases_Homo sapiens_hsa050200.47965941
86Gap junction_Homo sapiens_hsa045400.47690845
87p53 signaling pathway_Homo sapiens_hsa041150.47588548
88Circadian entrainment_Homo sapiens_hsa047130.46023645
89Salmonella infection_Homo sapiens_hsa051320.44931065
90ErbB signaling pathway_Homo sapiens_hsa040120.42752070
91Huntingtons disease_Homo sapiens_hsa050160.42629571
92Fatty acid degradation_Homo sapiens_hsa000710.41941360
93Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.41856505
94Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.41353322
95Axon guidance_Homo sapiens_hsa043600.41243996
96Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.40803211
97Endocytosis_Homo sapiens_hsa041440.39997930
98Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.38743413
99Long-term potentiation_Homo sapiens_hsa047200.38705676
100Salivary secretion_Homo sapiens_hsa049700.38457236
101Protein export_Homo sapiens_hsa030600.38388345
102Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.38213393
103Melanoma_Homo sapiens_hsa052180.37828609
104TGF-beta signaling pathway_Homo sapiens_hsa043500.37070962
105Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.36416813
106Estrogen signaling pathway_Homo sapiens_hsa049150.34359137
107Legionellosis_Homo sapiens_hsa051340.34217239
108Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.34202168
109Basal transcription factors_Homo sapiens_hsa030220.34006337
110Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.33639330
111Parkinsons disease_Homo sapiens_hsa050120.32857385
112Fatty acid metabolism_Homo sapiens_hsa012120.32287788
113PI3K-Akt signaling pathway_Homo sapiens_hsa041510.31300567
114PPAR signaling pathway_Homo sapiens_hsa033200.30080314
115Pentose phosphate pathway_Homo sapiens_hsa000300.29234293
116AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.29171390
117Fatty acid biosynthesis_Homo sapiens_hsa000610.28226643
118Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.27455845
119Phospholipase D signaling pathway_Homo sapiens_hsa040720.27272842
120GABAergic synapse_Homo sapiens_hsa047270.26358335
121Hippo signaling pathway_Homo sapiens_hsa043900.25790650
122Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.25371638
123Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.23021957
124Bile secretion_Homo sapiens_hsa049760.22019474
125Ovarian steroidogenesis_Homo sapiens_hsa049130.21995155
126Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.21594605
127Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.21520779
128Sulfur metabolism_Homo sapiens_hsa009200.21111513
129Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.20856124
130Neurotrophin signaling pathway_Homo sapiens_hsa047220.19577300
131Inositol phosphate metabolism_Homo sapiens_hsa005620.19402921
132Wnt signaling pathway_Homo sapiens_hsa043100.19160359
133Thyroid hormone synthesis_Homo sapiens_hsa049180.16761444
134Butanoate metabolism_Homo sapiens_hsa006500.16659603
135Colorectal cancer_Homo sapiens_hsa052100.16365205
136RNA degradation_Homo sapiens_hsa030180.16172876
137RNA polymerase_Homo sapiens_hsa030200.15202324

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