MYADM

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1collagen fibril organization (GO:0030199)4.75391162
2wound healing, spreading of epidermal cells (GO:0035313)4.71049717
3chondrocyte proliferation (GO:0035988)4.61515379
4endodermal cell differentiation (GO:0035987)4.52538317
5modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.51027687
6positive regulation by symbiont of host defense response (GO:0052509)4.51027687
7response to peptidoglycan (GO:0032494)4.49055680
8protein heterotrimerization (GO:0070208)4.48847822
9cell adhesion mediated by integrin (GO:0033627)4.42819398
10regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)4.34221282
11sequestering of extracellular ligand from receptor (GO:0035581)4.26224015
12cellular extravasation (GO:0045123)4.14476415
13basement membrane organization (GO:0071711)4.12831906
14neutrophil activation involved in immune response (GO:0002283)4.02296419
15skin morphogenesis (GO:0043589)3.99042033
16negative regulation of cell killing (GO:0031342)3.93377965
17negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.93377965
18antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.87264341
19regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.81916347
20plasma membrane repair (GO:0001778)3.81777255
21retina vasculature morphogenesis in camera-type eye (GO:0061299)3.78227144
22wound healing, spreading of cells (GO:0044319)3.75101946
23vascular endothelial growth factor signaling pathway (GO:0038084)3.72954307
24detection of molecule of bacterial origin (GO:0032490)3.65225075
25negative regulation of erythrocyte differentiation (GO:0045647)3.59419454
26antigen processing and presentation of endogenous antigen (GO:0019883)3.57725470
27apoptotic cell clearance (GO:0043277)3.56610967
28detection of other organism (GO:0098543)3.56351433
29regulation of tight junction assembly (GO:2000810)3.54162038
30epithelial cell-cell adhesion (GO:0090136)3.53242900
31antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.52943939
32positive regulation of gamma-delta T cell activation (GO:0046645)3.49986427
33response to muramyl dipeptide (GO:0032495)3.44441506
34endothelial cell morphogenesis (GO:0001886)3.42236469
35macrophage activation involved in immune response (GO:0002281)3.41956105
36positive regulation of endothelial cell apoptotic process (GO:2000353)3.41352477
37regulation of integrin-mediated signaling pathway (GO:2001044)3.37323001
38regulation of SMAD protein import into nucleus (GO:0060390)3.34110108
39neuron projection extension involved in neuron projection guidance (GO:1902284)3.33029592
40axon extension involved in axon guidance (GO:0048846)3.33029592
41extracellular fibril organization (GO:0043206)3.29207768
42leukocyte aggregation (GO:0070486)3.28989538
43atrioventricular valve morphogenesis (GO:0003181)3.28209088
44negative regulation of interleukin-8 production (GO:0032717)3.27539110
45detection of external biotic stimulus (GO:0098581)3.27013089
46detection of bacterium (GO:0016045)3.25374309
47collagen metabolic process (GO:0032963)3.23231697
48substrate-dependent cell migration (GO:0006929)3.20933206
49fibril organization (GO:0097435)3.20087326
50negative regulation of fatty acid transport (GO:2000192)3.19897518
51stress fiber assembly (GO:0043149)3.15474389
52positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.15168638
53antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.14455016
54regulation of mast cell degranulation (GO:0043304)3.14344674
55sarcomere organization (GO:0045214)3.13916621
56collagen catabolic process (GO:0030574)3.13245594
57negative regulation of interleukin-12 production (GO:0032695)3.12826287
58substrate adhesion-dependent cell spreading (GO:0034446)3.12094122
59response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.09550172
60response to host (GO:0075136)3.09550172
61response to host defenses (GO:0052200)3.09550172
62regulation of interferon-beta biosynthetic process (GO:0045357)3.09268692
63dermatan sulfate biosynthetic process (GO:0030208)3.09241204
64neutrophil activation (GO:0042119)3.09008019
65positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.08342333
66glomerular basement membrane development (GO:0032836)3.04608157
67extracellular matrix disassembly (GO:0022617)3.04492793
68lymphangiogenesis (GO:0001946)3.03476775
69regulation of leukocyte degranulation (GO:0043300)3.02591159
70detection of biotic stimulus (GO:0009595)3.01325379
71neutrophil mediated immunity (GO:0002446)3.01132895
72endocardial cushion development (GO:0003197)3.00368769
73multicellular organismal macromolecule metabolic process (GO:0044259)2.99081860
74regulation of T-helper 2 cell differentiation (GO:0045628)2.98797282
75negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.98706642
76positive regulation of SMAD protein import into nucleus (GO:0060391)2.97925329
77regulation of myeloid leukocyte mediated immunity (GO:0002886)2.97285306
78regulation of macrophage cytokine production (GO:0010935)2.97078136
79peptidyl-proline hydroxylation (GO:0019511)2.95249333
80cellular response to interferon-alpha (GO:0035457)2.95082704
81cell-substrate junction assembly (GO:0007044)2.93470606
82response to host immune response (GO:0052572)2.92584959
83response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.92584959
84bone trabecula formation (GO:0060346)2.92205207
85negative regulation of interleukin-6 production (GO:0032715)2.91968676
86keratan sulfate catabolic process (GO:0042340)2.91955314
87hippo signaling (GO:0035329)2.90027636
88positive regulation of epithelial to mesenchymal transition (GO:0010718)2.87487155
89multicellular organismal catabolic process (GO:0044243)2.85951470
90germinal center formation (GO:0002467)2.85655636
91renal filtration (GO:0097205)2.83371104
92cardiac myofibril assembly (GO:0055003)2.83141808
93regulation of mast cell activation involved in immune response (GO:0033006)2.82848971
94fibroblast migration (GO:0010761)2.81392514
95multicellular organismal metabolic process (GO:0044236)2.81383950
96tolerance induction (GO:0002507)2.80042497
97dermatan sulfate metabolic process (GO:0030205)2.79575017
98leukocyte migration involved in inflammatory response (GO:0002523)2.79554595
99cell migration involved in heart development (GO:0060973)2.79225413
100positive regulation of osteoblast proliferation (GO:0033690)2.78867767
101granulocyte activation (GO:0036230)2.78795609
102macrophage activation (GO:0042116)2.78526235
103positive regulation of blood vessel endothelial cell migration (GO:0043536)2.75739671
104hypotonic response (GO:0006971)2.72617529
105low-density lipoprotein particle clearance (GO:0034383)2.71127618
106regulation of gamma-delta T cell activation (GO:0046643)2.70782601
107cell migration involved in sprouting angiogenesis (GO:0002042)2.69304187
108microglial cell activation (GO:0001774)2.68872274
109protein hydroxylation (GO:0018126)2.67741764
110positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.66175768
111negative regulation of lymphocyte mediated immunity (GO:0002707)2.65988452
112barbed-end actin filament capping (GO:0051016)2.65462467
113regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.64707578
114atrial septum morphogenesis (GO:0060413)2.64686078
115negative regulation of phagocytosis (GO:0050765)2.63581079
116glomerular filtration (GO:0003094)2.62980999
117regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.62956005
118cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.62819611
119negative regulation of smooth muscle cell migration (GO:0014912)2.62777958
120mannose metabolic process (GO:0006013)2.62603072
121protein localization to cell surface (GO:0034394)2.62309030
122cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.62126481
123mRNA transcription from RNA polymerase II promoter (GO:0042789)2.62014505
124vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.60311872
125response to progesterone (GO:0032570)2.60148813
126response to fluid shear stress (GO:0034405)2.59404370
127regulation of B cell receptor signaling pathway (GO:0050855)2.57918166
128negative regulation of protein autophosphorylation (GO:0031953)2.57292539
129hemidesmosome assembly (GO:0031581)2.56847964
130actin-myosin filament sliding (GO:0033275)2.55979159
131muscle filament sliding (GO:0030049)2.55979159
132adherens junction assembly (GO:0034333)2.55384460
133regulation of tolerance induction (GO:0002643)2.55352298
134extracellular matrix organization (GO:0030198)2.54411274
135pinocytosis (GO:0006907)2.53479555
136extracellular structure organization (GO:0043062)2.53194819
137response to laminar fluid shear stress (GO:0034616)2.52369354
138lipopolysaccharide-mediated signaling pathway (GO:0031663)2.52287452
139regulation of cardioblast differentiation (GO:0051890)2.51204673
140regulation of regulated secretory pathway (GO:1903305)2.51151607
141platelet degranulation (GO:0002576)2.50069755
142negative regulation of cytokine production involved in immune response (GO:0002719)2.50068152
143negative regulation of leukocyte mediated immunity (GO:0002704)2.50010086
144positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511)2.49495912
145mesenchymal-epithelial cell signaling (GO:0060638)2.49409964
146negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.49213901
147negative regulation of chondrocyte differentiation (GO:0032331)2.48743762
148maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.48735548
149protein retention in ER lumen (GO:0006621)2.48461354
150immunoglobulin mediated immune response (GO:0016064)2.48110555
151negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.47882374
152myeloid cell activation involved in immune response (GO:0002275)2.47519851
153respiratory burst (GO:0045730)2.47187838
154craniofacial suture morphogenesis (GO:0097094)2.47034257
155extracellular matrix assembly (GO:0085029)2.46659545
156regulation of integrin activation (GO:0033623)2.46057196
157positive regulation of tolerance induction (GO:0002645)2.45928125
158regulation of dendritic cell antigen processing and presentation (GO:0002604)2.45746697
159negative regulation of T-helper cell differentiation (GO:0045623)2.44767910
160negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.44767910
161regulation of mast cell activation (GO:0033003)2.43590303
162angiogenesis involved in wound healing (GO:0060055)2.43292942
163myeloid leukocyte mediated immunity (GO:0002444)2.42666720
164negative regulation of T cell mediated immunity (GO:0002710)2.41621183
165mRNA transcription (GO:0009299)2.41602815
166endothelial cell proliferation (GO:0001935)2.40414720
167hyaluronan catabolic process (GO:0030214)2.40361022
168glomerular visceral epithelial cell development (GO:0072015)2.39871976
169mesodermal cell differentiation (GO:0048333)2.39436378
170embryonic process involved in female pregnancy (GO:0060136)2.39235262
171positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.38975548
172antigen processing and presentation via MHC class Ib (GO:0002475)2.38840888
173regulation of interleukin-8 biosynthetic process (GO:0045414)2.37947399
174negative regulation of type 2 immune response (GO:0002829)2.37809408
175regulation of T cell tolerance induction (GO:0002664)2.37256070
176positive regulation of mast cell activation (GO:0033005)2.36904387
177cellular response to vitamin (GO:0071295)2.36487651
178positive regulation of extracellular matrix organization (GO:1903055)2.36233425
179actin-mediated cell contraction (GO:0070252)2.35846826
180modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.35368176
181positive regulation by organism of defense response of other organism involved in symbiotic interact2.35368176
182modulation by symbiont of host immune response (GO:0052553)2.35368176
183modulation by symbiont of host defense response (GO:0052031)2.35368176
184positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.34689006
185positive regulation of receptor recycling (GO:0001921)2.32591759
186positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.30834153
187negative regulation of interleukin-1 production (GO:0032692)2.29884233
188regulation of gamma-delta T cell differentiation (GO:0045586)2.29859286

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human6.22136349
2TP63_17297297_ChIP-ChIP_HaCaT_Human5.63554365
3RARG_19884340_ChIP-ChIP_MEFs_Mouse4.81468594
4NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.44950920
5TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.16495969
6* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.93964892
7CLOCK_20551151_ChIP-Seq_293T_Human2.88793084
8RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.81549569
9PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.66590873
10HIF1A_21447827_ChIP-Seq_MCF-7_Human2.60467636
11VDR_24763502_ChIP-Seq_THP-1_Human2.52819911
12CJUN_26792858_Chip-Seq_BT549_Human2.49656556
13CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.47784698
14SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.42867366
15VDR_21846776_ChIP-Seq_THP-1_Human2.41758577
16MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.37136565
17* EGR1_19374776_ChIP-ChIP_THP-1_Human2.31788607
18EP300_21415370_ChIP-Seq_HL-1_Mouse2.23884987
19* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.19058145
20* ELK3_25401928_ChIP-Seq_HUVEC_Human2.17940630
21CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.17908621
22BRD4_25478319_ChIP-Seq_HGPS_Human2.11319759
23* TCF7_22412390_ChIP-Seq_EML_Mouse2.09566674
24SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.06512485
25SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.06512485
26WT1_19549856_ChIP-ChIP_CCG9911_Human2.05083730
27SMAD_19615063_ChIP-ChIP_OVARY_Human2.04158870
28ESR1_21235772_ChIP-Seq_MCF-7_Human2.03968208
29ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.99108650
30NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.95173230
31* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.93552445
32VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.92598499
33ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.92427395
34KDM2B_26808549_Chip-Seq_DND41_Human1.91128273
35IRF8_21731497_ChIP-ChIP_J774_Mouse1.88841448
36NRF2_20460467_ChIP-Seq_MEFs_Mouse1.87993924
37NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.87993924
38GATA2_21666600_ChIP-Seq_HMVEC_Human1.86995663
39STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.86489231
40RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.84397823
41SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.83691690
42TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.82165986
43* RUNX1_22412390_ChIP-Seq_EML_Mouse1.80066851
44ESR2_21235772_ChIP-Seq_MCF-7_Human1.77526378
45RUNX_20019798_ChIP-Seq_JUKART_Human1.76170161
46SALL4_18804426_ChIP-ChIP_XEN_Mouse1.75673259
47PPAR_26484153_Chip-Seq_NCI-H1993_Human1.74389425
48BP1_19119308_ChIP-ChIP_Hs578T_Human1.71540300
49LXR_22292898_ChIP-Seq_THP-1_Human1.70751927
50* MAF_26560356_Chip-Seq_TH1_Human1.70454541
51* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.70383273
52Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.70044865
53STAT6_21828071_ChIP-Seq_BEAS2B_Human1.66455765
54EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.64980438
55FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.61504327
56MYC_22102868_ChIP-Seq_BL_Human1.60574720
57MYB_21317192_ChIP-Seq_ERMYB_Mouse1.59340644
58PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.58383781
59* SOX2_20726797_ChIP-Seq_SW620_Human1.57580351
60MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.55510690
61* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.54428476
62ATF3_27146783_Chip-Seq_COLON_Human1.53944197
63* UTX_26944678_Chip-Seq_JUKART_Human1.53846823
64FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.53733574
65WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.51801041
66TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50384725
67* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.49634981
68CDX2_19796622_ChIP-Seq_MESCs_Mouse1.48232085
69TBX20_22080862_ChIP-Seq_HEART_Mouse1.47822611
70TBX20_22328084_ChIP-Seq_HEART_Mouse1.47822611
71E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.46856848
72SCL_19346495_ChIP-Seq_HPC-7_Human1.46772061
73STAT4_19710469_ChIP-ChIP_TH1__Mouse1.46547628
74UBF1/2_26484160_Chip-Seq_HMECs_Human1.45605778
75NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.45172695
76* SPI1_23547873_ChIP-Seq_NB4_Human1.44442521
77* KDM2B_26808549_Chip-Seq_JURKAT_Human1.44152800
78KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.43823709
79IRF8_22096565_ChIP-ChIP_GC-B_Human1.39736567
80P300_27058665_Chip-Seq_ZR-75-30cells_Human1.38721964
81IRF8_27001747_Chip-Seq_BMDM_Mouse1.38213643
82NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.36636412
83FOXO3_23340844_ChIP-Seq_DLD1_Human1.35591246
84* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.35577741
85KDM2B_26808549_Chip-Seq_K562_Human1.33560169
86SOX9_24532713_ChIP-Seq_HFSC_Mouse1.30013266
87SMC1_22415368_ChIP-Seq_MEFs_Mouse1.29975202
88STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.29836412
89* RACK7_27058665_Chip-Seq_MCF-7_Human1.27835256
90NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.25974217
91* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.24768073
92MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.24156717
93* MYB_26560356_Chip-Seq_TH2_Human1.22959603
94SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.22380068
95THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.22058473
96TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.21379912
97STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.20358261
98CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.20276692
99MAF_26560356_Chip-Seq_TH2_Human1.19857195
100* MYB_26560356_Chip-Seq_TH1_Human1.18373536
101UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.17887616
102TP53_22127205_ChIP-Seq_IMR90_Human1.17132966
103ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.16911022
104TP53_18474530_ChIP-ChIP_U2OS_Human1.16339016
105KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.15627106
106POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.15509209
107TP53_16413492_ChIP-PET_HCT116_Human1.13537498
108GATA1_19941827_ChIP-Seq_MEL_Mouse1.12615621
109SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.12535145
110P63_26484246_Chip-Seq_KERATINOCYTES_Human1.12078914
111SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.10108369
112LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.10084334
113* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08268524
114TP53_23651856_ChIP-Seq_MEFs_Mouse1.07877208
115EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.07751496
116PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.06640896
117CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.06364042
118NFIB_24661679_ChIP-Seq_LUNG_Mouse1.04938813
119ELK1_22589737_ChIP-Seq_MCF10A_Human1.04136853
120TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.04130616
121* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.03992347
122VDR_24787735_ChIP-Seq_THP-1_Human1.03554595
123GATA1_19941826_ChIP-Seq_K562_Human1.03005303
124* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.02583831
125BRD4_27068464_Chip-Seq_AML-cells_Mouse1.02473059
126CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01615200
127ZNF217_24962896_ChIP-Seq_MCF-7_Human1.01069891
128TCF3_18692474_ChIP-Seq_MEFs_Mouse1.00879769
129IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.00239330
130TP53_20018659_ChIP-ChIP_R1E_Mouse0.99206280
131HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.98560770
132TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.98467280
133ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.97796850
134ESR1_20079471_ChIP-ChIP_T-47D_Human0.97703741
135GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.96523968
136GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.96241795
137SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.96209416
138KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.96169846
139GATA1_22383799_ChIP-Seq_G1ME_Mouse0.95580913
140CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.95013352
141ZFP281_18757296_ChIP-ChIP_E14_Mouse0.94881035
142STAT3_1855785_ChIP-Seq_MESCs_Mouse0.92872919
143FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.90972819
144GATA4_21415370_ChIP-Seq_HL-1_Mouse0.90251390
145SPI1_23127762_ChIP-Seq_K562_Human0.89090323
146SMC3_22415368_ChIP-Seq_MEFs_Mouse0.89008170

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen6.42051787
2MP0005275_abnormal_skin_tensile4.01456750
3MP0005503_abnormal_tendon_morphology3.97485599
4MP0003279_aneurysm3.74824550
5MP0003705_abnormal_hypodermis_morpholog3.73948789
6MP0004272_abnormal_basement_membrane2.97438741
7MP0003566_abnormal_cell_adhesion2.97228900
8MP0001958_emphysema2.91820895
9MP0002419_abnormal_innate_immunity2.37028229
10MP0003191_abnormal_cellular_cholesterol2.35850195
11MP0010368_abnormal_lymphatic_system2.32603361
12MP0005623_abnormal_meninges_morphology2.22308901
13MP0001835_abnormal_antigen_presentation2.07276273
14MP0006054_spinal_hemorrhage2.02000840
15MP0003828_pulmonary_edema1.99252903
16MP0005023_abnormal_wound_healing1.98638096
17MP0004084_abnormal_cardiac_muscle1.95586943
18MP0009384_cardiac_valve_regurgitation1.94096546
19MP0005257_abnormal_intraocular_pressure1.92919851
20MP0003091_abnormal_cell_migration1.90199267
21MP0005025_abnormal_response_to1.86716735
22MP0000685_abnormal_immune_system1.83845564
23MP0010352_gastrointestinal_tract_polyps1.78667745
24MP0005508_abnormal_skeleton_morphology1.77506924
25MP0000767_abnormal_smooth_muscle1.67577784
26MP0003172_abnormal_lysosome_physiology1.66712940
27MP0005000_abnormal_immune_tolerance1.65488591
28MP0000750_abnormal_muscle_regeneration1.65320502
29MP0001542_abnormal_bone_strength1.64634653
30MP0004947_skin_inflammation1.64399471
31MP0001851_eye_inflammation1.61848003
32MP0001879_abnormal_lymphatic_vessel1.60960056
33MP0009785_altered_susceptibility_to1.57441478
34MP0002132_abnormal_respiratory_system1.56019796
35MP0006082_CNS_inflammation1.55049366
36MP0002295_abnormal_pulmonary_circulatio1.53740938
37MP0005464_abnormal_platelet_physiology1.53543703
38MP0001790_abnormal_immune_system1.53514770
39MP0005387_immune_system_phenotype1.53514770
40MP0002405_respiratory_system_inflammati1.53353883
41MP0000343_altered_response_to1.53022468
42MP0002837_dystrophic_cardiac_calcinosis1.53014314
43MP0002452_abnormal_antigen_presenting1.53000838
44MP0002420_abnormal_adaptive_immunity1.51264149
45MP0001819_abnormal_immune_cell1.49976298
46MP0002723_abnormal_immune_serum1.48893788
47MP0001800_abnormal_humoral_immune1.48626712
48MP0002877_abnormal_melanocyte_morpholog1.46442177
49MP0003303_peritoneal_inflammation1.45258193
50MP0002148_abnormal_hypersensitivity_rea1.43724373
51MP0001533_abnormal_skeleton_physiology1.43547576
52MP0005390_skeleton_phenotype1.42491005
53MP0003941_abnormal_skin_development1.42364095
54MP0002060_abnormal_skin_morphology1.42262498
55MP0000751_myopathy1.41556132
56MP0000733_abnormal_muscle_development1.40650993
57MP0002933_joint_inflammation1.33747569
58MP0008260_abnormal_autophagy1.31514734
59MP0000749_muscle_degeneration1.31003062
60MP0008775_abnormal_heart_ventricle1.29901927
61MP0005076_abnormal_cell_differentiation1.28686899
62MP0005330_cardiomyopathy1.24534777
63MP0003950_abnormal_plasma_membrane1.23245590
64MP0003075_altered_response_to1.22400149
65MP0010030_abnormal_orbit_morphology1.20820287
66MP0009840_abnormal_foam_cell1.20575493
67MP0000516_abnormal_urinary_system1.20452267
68MP0005367_renal/urinary_system_phenotyp1.20452267
69MP0003385_abnormal_body_wall1.19283947
70MP0004087_abnormal_muscle_fiber1.19126757
71MP0002972_abnormal_cardiac_muscle1.18753409
72MP0010630_abnormal_cardiac_muscle1.17013246
73MP0004510_myositis1.15998615
74MP0003436_decreased_susceptibility_to1.15918370
75MP0006138_congestive_heart_failure1.15509524
76MP0003448_altered_tumor_morphology1.13895965
77MP0002108_abnormal_muscle_morphology1.11974348
78MP0003724_increased_susceptibility_to1.10962467
79MP0003300_gastrointestinal_ulcer1.08873311
80MP0002166_altered_tumor_susceptibility1.07757497
81MP0001544_abnormal_cardiovascular_syste1.07739869
82MP0005385_cardiovascular_system_phenoty1.07739869
83MP0002896_abnormal_bone_mineralization1.07490356
84MP0002128_abnormal_blood_circulation1.07386179
85MP0009250_abnormal_appendicular_skeleto1.06982520
86MP0001845_abnormal_inflammatory_respons1.06645463
87MP0000465_gastrointestinal_hemorrhage1.06417158
88MP0003763_abnormal_thymus_physiology1.05664249
89MP0002396_abnormal_hematopoietic_system1.05048091
90MP0000716_abnormal_immune_system1.04821976
91MP0001853_heart_inflammation1.04668897
92MP0001243_abnormal_dermal_layer1.04372697
93MP0002398_abnormal_bone_marrow1.03891114
94MP0004808_abnormal_hematopoietic_stem1.03639566
95MP0003045_fibrosis1.01646355
96MP0005166_decreased_susceptibility_to1.01228381
97MP0001614_abnormal_blood_vessel0.99141607
98MP0005083_abnormal_biliary_tract0.99062488
99MP0000013_abnormal_adipose_tissue0.99027075
100MP0005451_abnormal_body_composition0.99004446
101MP0005164_abnormal_response_to0.97362809
102MP0005058_abnormal_lysosome_morphology0.96869143
103MP0005397_hematopoietic_system_phenotyp0.96749239
104MP0001545_abnormal_hematopoietic_system0.96749239
105MP0000858_altered_metastatic_potential0.96220748
106MP0009053_abnormal_anal_canal0.96179249
107MP0009333_abnormal_splenocyte_physiolog0.95186793
108MP0002998_abnormal_bone_remodeling0.94948444
109MP0002925_abnormal_cardiovascular_devel0.94510373
110MP0010155_abnormal_intestine_physiology0.94214773
111MP0005595_abnormal_vascular_smooth0.93172473
112MP0009764_decreased_sensitivity_to0.92069288
113MP0000163_abnormal_cartilage_morphology0.90864322
114MP0005620_abnormal_muscle_contractility0.90638647
115MP0002282_abnormal_trachea_morphology0.90252087
116MP0003567_abnormal_fetal_cardiomyocyte0.89804134
117MP0008469_abnormal_protein_level0.89637645
118MP0004883_abnormal_blood_vessel0.88372185
119MP0002722_abnormal_immune_system0.87964289
120MP0000759_abnormal_skeletal_muscle0.87678708
121MP0002168_other_aberrant_phenotype0.87142008
122MP0008004_abnormal_stomach_pH0.85062695
123MP0002429_abnormal_blood_cell0.84963576
124MP0001299_abnormal_eye_distance/0.84849621
125MP0001175_abnormal_lung_morphology0.84774081
126MP0005671_abnormal_response_to0.84724202
127MP0004036_abnormal_muscle_relaxation0.83720160
128MP0002115_abnormal_skeleton_extremities0.83676602
129MP0000249_abnormal_blood_vessel0.82712982
130MP0002113_abnormal_skeleton_development0.82426164
131MP0005409_darkened_coat_color0.81796081
132MP0002133_abnormal_respiratory_system0.81372606
133MP0005388_respiratory_system_phenotype0.81372606
134MP0009278_abnormal_bone_marrow0.81004754
135MP0002254_reproductive_system_inflammat0.80550418
136MP0000266_abnormal_heart_morphology0.80358092
137MP0004484_altered_response_of0.79731673
138MP0000703_abnormal_thymus_morphology0.79614987
139MP0005165_increased_susceptibility_to0.79527864
140MP0002009_preneoplasia0.78741312
141MP0000689_abnormal_spleen_morphology0.78471824
142MP0005369_muscle_phenotype0.77491978
143MP0003795_abnormal_bone_structure0.76031296
144MP0004233_abnormal_muscle_weight0.75557551
145MP0002106_abnormal_muscle_physiology0.73868551
146MP0003866_abnormal_defecation0.73393634
147MP0003115_abnormal_respiratory_system0.72428127
148MP0004858_abnormal_nervous_system0.70684876
149MP0000534_abnormal_ureter_morphology0.69033548
150MP0000428_abnormal_craniofacial_morphol0.68902969
151MP0000003_abnormal_adipose_tissue0.68252137
152MP0001915_intracranial_hemorrhage0.67771547

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)7.30840485
2Premature rupture of membranes (HP:0001788)7.06928385
3Aortic dissection (HP:0002647)4.48640005
4Aortic aneurysm (HP:0004942)4.34802060
5Cerebral aneurysm (HP:0004944)4.33872578
6Eczematoid dermatitis (HP:0000976)4.06758742
7Shallow orbits (HP:0000586)3.93555077
8Vertebral compression fractures (HP:0002953)3.91144829
9Myositis (HP:0100614)3.90907260
10Ankle contracture (HP:0006466)3.90537691
11Cervical subluxation (HP:0003308)3.83417270
12Elevated erythrocyte sedimentation rate (HP:0003565)3.83001525
13Increased connective tissue (HP:0009025)3.82695418
14Soft skin (HP:0000977)3.82223770
15Atrophic scars (HP:0001075)3.70578161
16Peritonitis (HP:0002586)3.66605162
17Dilatation of the ascending aorta (HP:0005111)3.64136389
18Abnormality of macrophages (HP:0004311)3.62371968
19Recurrent abscess formation (HP:0002722)3.51298521
20Orchitis (HP:0100796)3.46396992
21Spinal rigidity (HP:0003306)3.36243041
22Broad metatarsal (HP:0001783)3.24950060
23Recurrent bacterial skin infections (HP:0005406)3.20989460
24Fragile skin (HP:0001030)3.18531164
25Osteolytic defects of the hand bones (HP:0009699)3.17919878
26Osteolytic defects of the phalanges of the hand (HP:0009771)3.17919878
27Amyloidosis (HP:0011034)3.17515333
28Wormian bones (HP:0002645)3.15509316
29Right ventricular cardiomyopathy (HP:0011663)3.14325616
30Wrist flexion contracture (HP:0001239)3.05998419
31Bladder diverticulum (HP:0000015)3.00410825
32Biconcave vertebral bodies (HP:0004586)2.97909370
33Type 1 muscle fiber predominance (HP:0003803)2.95315741
34Genu recurvatum (HP:0002816)2.92191395
35Short nail (HP:0001799)2.89962193
36Blue sclerae (HP:0000592)2.88726855
37Stomatitis (HP:0010280)2.87684984
38Recurrent gram-negative bacterial infections (HP:0005420)2.86899488
39Optic neuritis (HP:0100653)2.77660536
40Retrobulbar optic neuritis (HP:0100654)2.77660536
41Vascular tortuosity (HP:0004948)2.77298999
42Mitral valve prolapse (HP:0001634)2.73908926
43Abnormality of dentin (HP:0010299)2.70093185
44Aneurysm (HP:0002617)2.62900562
45Muscle fiber splitting (HP:0003555)2.62231248
46Follicular hyperkeratosis (HP:0007502)2.54504166
47Spontaneous hematomas (HP:0007420)2.50298851
48Mildly elevated creatine phosphokinase (HP:0008180)2.47571867
49Arterial tortuosity (HP:0005116)2.47470135
50Distal lower limb muscle weakness (HP:0009053)2.47456340
51Abnormality of the acetabulum (HP:0003170)2.46234699
52Spondylolisthesis (HP:0003302)2.46126457
53Cellulitis (HP:0100658)2.44118454
54Neonatal short-limb short stature (HP:0008921)2.43831765
55Gastrointestinal infarctions (HP:0005244)2.41210552
56Prolonged bleeding time (HP:0003010)2.38568462
57Episodic fever (HP:0001954)2.37054558
58Ventricular tachycardia (HP:0004756)2.37045306
59Polygenic inheritance (HP:0010982)2.35912314
60Overgrowth (HP:0001548)2.35008059
61Difficulty climbing stairs (HP:0003551)2.33869895
62Hyperextensible skin (HP:0000974)2.32624810
63Recurrent fungal infections (HP:0002841)2.32319360
64Interstitial pulmonary disease (HP:0006530)2.29130792
65Broad face (HP:0000283)2.26236946
66Obstructive sleep apnea (HP:0002870)2.25379905
67Slender build (HP:0001533)2.23943611
68Coxa vara (HP:0002812)2.23314787
69Lipoatrophy (HP:0100578)2.22502096
70Increased variability in muscle fiber diameter (HP:0003557)2.21669772
71Elbow flexion contracture (HP:0002987)2.21055432
72Increased IgE level (HP:0003212)2.20228255
73Gingivitis (HP:0000230)2.19732776
74Abnormal delayed hypersensitivity skin test (HP:0002963)2.19727284
75Mediastinal lymphadenopathy (HP:0100721)2.19173556
76Abnormal delivery (HP:0001787)2.16876640
77Recurrent skin infections (HP:0001581)2.15405010
78Chronic obstructive pulmonary disease (HP:0006510)2.14227041
79Obstructive lung disease (HP:0006536)2.14227041
80Increased density of long bones (HP:0006392)2.13086252
81Epistaxis (HP:0000421)2.10034516
82Dysostosis multiplex (HP:0000943)2.09749952
83Distal lower limb amyotrophy (HP:0008944)2.09584424
84Abnormality of skeletal muscle fiber size (HP:0012084)2.09386184
85Camptodactyly of toe (HP:0001836)2.08841904
86Sudden death (HP:0001699)2.08630984
87Beaking of vertebral bodies (HP:0004568)2.07233329
88Joint laxity (HP:0001388)2.05974552
89Abnormality of the distal phalanges of the toes (HP:0010182)2.05934942
90Scapular winging (HP:0003691)2.05416254
91Syringomyelia (HP:0003396)2.05017456
92Spinal cord lesions (HP:0100561)2.05017456
93Myocardial infarction (HP:0001658)2.04418721
94Joint stiffness (HP:0001387)2.04156862
95Urticaria (HP:0001025)2.03400106
96Hyporeflexia of lower limbs (HP:0002600)2.03241688
97Pulmonary infiltrates (HP:0002113)2.01120991
98Abnormality of glycolipid metabolism (HP:0010969)2.01015861
99Abnormality of liposaccharide metabolism (HP:0010968)2.01015861
100Abnormality of glycosphingolipid metabolism (HP:0004343)2.01015861
101Disproportionate tall stature (HP:0001519)2.00860079
102Thin bony cortex (HP:0002753)2.00193753
103Gingival bleeding (HP:0000225)1.98913244
104Keratoconjunctivitis sicca (HP:0001097)1.98815881
105Polycythemia (HP:0001901)1.97872851
106Abnormality of polysaccharide metabolism (HP:0011012)1.96568036
107Abnormality of glycosaminoglycan metabolism (HP:0004371)1.96568036
108Abnormality of mucopolysaccharide metabolism (HP:0011020)1.96568036
109Hematochezia (HP:0002573)1.96084510
110Meningitis (HP:0001287)1.95893268
111Mucopolysacchariduria (HP:0008155)1.93996442
112Urinary glycosaminoglycan excretion (HP:0003541)1.93996442
113Distal upper limb amyotrophy (HP:0007149)1.93199518
114Upper limb amyotrophy (HP:0009129)1.93199518
115Abnormality of the calf musculature (HP:0001430)1.92909095
116Generalized amyotrophy (HP:0003700)1.92209281
117Vasculitis (HP:0002633)1.91370495
118Chest pain (HP:0100749)1.90775775
119Chronic mucocutaneous candidiasis (HP:0002728)1.90126567
120Recurrent cutaneous fungal infections (HP:0011370)1.90126567
121Wide anterior fontanel (HP:0000260)1.89513663
122Atrial fibrillation (HP:0005110)1.88471647
123Segmental peripheral demyelination/remyelination (HP:0003481)1.86793072
124Round ear (HP:0100830)1.86687043
125Fused cervical vertebrae (HP:0002949)1.86448950
126EMG: myopathic abnormalities (HP:0003458)1.85143155
127Mitral regurgitation (HP:0001653)1.84757615
128Bruising susceptibility (HP:0000978)1.83118068
129Platyspondyly (HP:0000926)1.82682307
130Venous abnormality (HP:0002624)1.82366117
131Aortic valve stenosis (HP:0001650)1.81804063
132Abnormality of the pericardium (HP:0001697)1.81745220
133Bowel diverticulosis (HP:0005222)1.80476861
134Hemoptysis (HP:0002105)1.80111439
135Nonimmune hydrops fetalis (HP:0001790)1.79743139
136Mesomelia (HP:0003027)1.79127430
137Primary atrial arrhythmia (HP:0001692)1.78426076
138Pulmonary artery stenosis (HP:0004415)1.77523270
139Osteopenia (HP:0000938)1.76905832
140Radial bowing (HP:0002986)1.76791552
141Spinal cord compression (HP:0002176)1.76698741
142Petechiae (HP:0000967)1.75358193
143Arterial thrombosis (HP:0004420)1.75067890
144Leukocytosis (HP:0001974)1.75027534
145Hypertriglyceridemia (HP:0002155)1.74196364
146Supraventricular arrhythmia (HP:0005115)1.73240615
147Hypoplastic ischia (HP:0003175)1.72997387
148Ectopia lentis (HP:0001083)1.72832904
149Persistence of primary teeth (HP:0006335)1.72758515
150Hand muscle atrophy (HP:0009130)1.72477788
151Abnormality of skull ossification (HP:0002703)1.70411886
152Asymmetric septal hypertrophy (HP:0001670)1.70101985
153Limb-girdle muscle atrophy (HP:0003797)1.67608527
154Flexion contracture of toe (HP:0005830)1.67590414
155Joint contractures involving the joints of the feet (HP:0100492)1.67590414
156Osteoarthritis (HP:0002758)1.67502056
157Abnormality of the peritoneum (HP:0002585)1.67219642
158Knee flexion contracture (HP:0006380)1.66082365
159Hip contracture (HP:0003273)1.65727042
160Decreased skull ossification (HP:0004331)1.65235261

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN4.12880949
2TRIB33.15373984
3DDR22.86891773
4ERN12.85875513
5PRPF4B2.73777078
6RIPK42.73292550
7PIM22.52625201
8DMPK2.48370185
9TESK12.43520471
10MYLK2.43203681
11LATS22.40281049
12PDGFRA2.06256495
13EPHA22.03525991
14ZAP702.02306152
15LATS12.00110755
16PKN21.99639166
17TGFBR21.97275311
18LIMK11.93598104
19EPHB21.88164112
20MAP4K11.88012861
21FER1.86964932
22PTK2B1.86647759
23TYK21.86479491
24IRAK41.86395346
25TRPM71.79132262
26MAP3K31.73881409
27NEK91.70557384
28KDR1.68107422
29PRKD21.66481399
30PTK21.66349355
31PAK21.65376298
32STK241.60574452
33RIPK11.49310127
34FES1.48232981
35GRK61.47251449
36STK38L1.46699799
37BMX1.44567327
38LRRK21.43513308
39PAK41.40545130
40STK101.39454462
41STK31.37703964
42PIK3CA1.37359968
43MAP3K141.35586516
44SIK31.34751142
45RPS6KA41.34356006
46KIT1.31909969
47MARK21.31070954
48TNK21.30391507
49SMG11.23317737
50MAP3K11.21602116
51PAK31.21523759
52MAPKAPK31.20410053
53MET1.18109092
54TAOK21.18024334
55EPHA31.16660477
56MOS1.13794866
57BTK1.11712380
58MAPK71.11669103
59STK381.10804980
60SIK11.10754683
61MAP2K31.10602010
62ILK1.09933063
63ROCK11.08218905
64MAPK151.07838643
65MAP3K61.06863324
66TESK21.03260481
67PRKG21.00661039
68PTK60.97738914
69NME20.97115706
70HIPK20.96950675
71CSF1R0.94413230
72MAP3K130.92631917
73KSR20.92354595
74MAP3K70.91548693
75MAP2K10.91024241
76EPHB10.90493302
77TGFBR10.89056203
78PIK3CG0.88545993
79TIE10.88280190
80DAPK30.86847856
81IRAK10.86246962
82IKBKE0.84089712
83TBK10.81067707
84ZAK0.80539586
85ERBB30.80284400
86PDPK10.77387422
87FGFR40.74153370
88IRAK20.73818265
89RPS6KA20.72700722
90FRK0.71474379
91JAK20.71376613
92MAP3K50.70948716
93CDK60.70935052
94ABL20.69787949
95CSK0.69471587
96RPS6KL10.68863036
97RPS6KC10.68863036
98CDC42BPA0.68308832
99PLK20.68072903
100MAPK120.67757921
101ICK0.67102423
102FLT30.66155186
103FGFR10.64087315
104MAP3K110.63721366
105MTOR0.63598864
106SYK0.63128010
107YES10.63049517
108FGR0.62789912
109PDK10.61898552
110MAP3K20.60890872
111PDGFRB0.60787055
112GSK3A0.59609088
113LCK0.59335271
114MAPKAPK20.59214843
115PRKD10.59069419
116CDK120.58289657
117TAOK30.56753846
118IKBKB0.56728716
119NEK10.56479203
120NUAK10.55497920
121TEC0.53694490
122PAK10.53667271
123LMTK20.53053479
124RPS6KA60.53021324
125IRAK30.52473291
126JAK10.51891725
127CAMK1D0.51391846
128OBSCN0.51193019
129EIF2AK10.50418776
130LYN0.49151751
131MAP3K80.48084088
132DYRK1B0.47385622
133GRK70.46770478
134AKT30.46133360
135JAK30.45789175
136ITK0.45735941
137MARK30.43724315
138RET0.43680628
139EGFR0.42796249
140ROCK20.42457662
141HCK0.40879429
142NTRK10.40371013
143INSR0.39401840
144BLK0.38757316
145SRC0.37880675
146MST1R0.37850444
147PDK20.36433156
148FGFR30.36412328
149ABL10.35217373
150CAMKK10.34495772
151TAOK10.33672370
152IGF1R0.30055541
153PRKCE0.29624486
154RPS6KB20.29488753

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.14615816
2Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.67962567
3Focal adhesion_Homo sapiens_hsa045102.65432250
4Dilated cardiomyopathy_Homo sapiens_hsa054142.47932929
5Bacterial invasion of epithelial cells_Homo sapiens_hsa051002.36014779
6Adherens junction_Homo sapiens_hsa045202.32330282
7Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.25002550
8Malaria_Homo sapiens_hsa051442.19801662
9Amoebiasis_Homo sapiens_hsa051462.14161643
10Proteoglycans in cancer_Homo sapiens_hsa052052.13792099
11Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.10269485
12AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049332.00286592
13Viral myocarditis_Homo sapiens_hsa054161.97154120
14Shigellosis_Homo sapiens_hsa051311.89164895
15Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.83458906
16Leukocyte transendothelial migration_Homo sapiens_hsa046701.83336931
17Leishmaniasis_Homo sapiens_hsa051401.77758353
18Small cell lung cancer_Homo sapiens_hsa052221.65334541
19Bladder cancer_Homo sapiens_hsa052191.65022867
20Regulation of actin cytoskeleton_Homo sapiens_hsa048101.55414739
21TGF-beta signaling pathway_Homo sapiens_hsa043501.54641414
22Salmonella infection_Homo sapiens_hsa051321.54334412
23Toxoplasmosis_Homo sapiens_hsa051451.46965300
24Pertussis_Homo sapiens_hsa051331.40946447
25MicroRNAs in cancer_Homo sapiens_hsa052061.39976414
26Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.39873393
27Chronic myeloid leukemia_Homo sapiens_hsa052201.36250961
28Phagosome_Homo sapiens_hsa041451.34666826
29Hippo signaling pathway_Homo sapiens_hsa043901.33011496
30Lysosome_Homo sapiens_hsa041421.31438749
31TNF signaling pathway_Homo sapiens_hsa046681.31298141
32Protein digestion and absorption_Homo sapiens_hsa049741.31183200
33Osteoclast differentiation_Homo sapiens_hsa043801.27756868
34Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.26139394
35HIF-1 signaling pathway_Homo sapiens_hsa040661.24145896
36PI3K-Akt signaling pathway_Homo sapiens_hsa041511.23058058
37T cell receptor signaling pathway_Homo sapiens_hsa046601.21541600
38Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.18587434
39Legionellosis_Homo sapiens_hsa051341.17220066
40Platelet activation_Homo sapiens_hsa046111.16892784
41Notch signaling pathway_Homo sapiens_hsa043301.16631390
42Glycosaminoglycan degradation_Homo sapiens_hsa005311.16612311
43Toll-like receptor signaling pathway_Homo sapiens_hsa046201.16012279
44Melanoma_Homo sapiens_hsa052181.15821238
45Tuberculosis_Homo sapiens_hsa051521.15536449
46Non-small cell lung cancer_Homo sapiens_hsa052231.14621123
47Apoptosis_Homo sapiens_hsa042101.11577627
48p53 signaling pathway_Homo sapiens_hsa041151.11331852
49Hepatitis C_Homo sapiens_hsa051601.08643488
50Pancreatic cancer_Homo sapiens_hsa052121.04471496
51Tight junction_Homo sapiens_hsa045301.03729880
52Hepatitis B_Homo sapiens_hsa051611.02135338
53Rap1 signaling pathway_Homo sapiens_hsa040151.00152003
54Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.96318883
55Graft-versus-host disease_Homo sapiens_hsa053320.93346999
56Renal cell carcinoma_Homo sapiens_hsa052110.92222852
57Rheumatoid arthritis_Homo sapiens_hsa053230.91119541
58Pathways in cancer_Homo sapiens_hsa052000.90811728
59Phospholipase D signaling pathway_Homo sapiens_hsa040720.88856942
60Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.87715157
61Prostate cancer_Homo sapiens_hsa052150.85953397
62MAPK signaling pathway_Homo sapiens_hsa040100.84280723
63Neurotrophin signaling pathway_Homo sapiens_hsa047220.83504123
64GnRH signaling pathway_Homo sapiens_hsa049120.82966056
65Staphylococcus aureus infection_Homo sapiens_hsa051500.82375408
66Glioma_Homo sapiens_hsa052140.80987834
67Allograft rejection_Homo sapiens_hsa053300.80804504
68HTLV-I infection_Homo sapiens_hsa051660.80483088
69RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.80040828
70Herpes simplex infection_Homo sapiens_hsa051680.79506969
71Autoimmune thyroid disease_Homo sapiens_hsa053200.76195169
72Choline metabolism in cancer_Homo sapiens_hsa052310.75810962
73Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.75697685
74VEGF signaling pathway_Homo sapiens_hsa043700.75370299
75Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.75234778
76Endocytosis_Homo sapiens_hsa041440.74890717
77Prolactin signaling pathway_Homo sapiens_hsa049170.74411580
78Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.72984070
79Acute myeloid leukemia_Homo sapiens_hsa052210.72801153
80Central carbon metabolism in cancer_Homo sapiens_hsa052300.71137511
81Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.69777093
82NF-kappa B signaling pathway_Homo sapiens_hsa040640.69643959
83Hematopoietic cell lineage_Homo sapiens_hsa046400.69513509
84Insulin resistance_Homo sapiens_hsa049310.69123200
85Thyroid cancer_Homo sapiens_hsa052160.68090014
86Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.66906014
87Influenza A_Homo sapiens_hsa051640.65808659
88Other glycan degradation_Homo sapiens_hsa005110.64851486
89ErbB signaling pathway_Homo sapiens_hsa040120.64353037
90Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.61520561
91Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.60748282
92Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.59530040
93Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.59255354
94Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.58914810
95Colorectal cancer_Homo sapiens_hsa052100.57541406
96Endometrial cancer_Homo sapiens_hsa052130.56305673
97SNARE interactions in vesicular transport_Homo sapiens_hsa041300.56288022
98FoxO signaling pathway_Homo sapiens_hsa040680.56037770
99Renin-angiotensin system_Homo sapiens_hsa046140.54099538
100Measles_Homo sapiens_hsa051620.53890539
101Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.52567640
102Viral carcinogenesis_Homo sapiens_hsa052030.51139158
103Jak-STAT signaling pathway_Homo sapiens_hsa046300.50623879
104Longevity regulating pathway - mammal_Homo sapiens_hsa042110.50179530
105Vibrio cholerae infection_Homo sapiens_hsa051100.50084293
106Basal cell carcinoma_Homo sapiens_hsa052170.49220507
107Sphingolipid signaling pathway_Homo sapiens_hsa040710.48797984
108NOD-like receptor signaling pathway_Homo sapiens_hsa046210.48751106
109Thyroid hormone signaling pathway_Homo sapiens_hsa049190.48628077
110Vascular smooth muscle contraction_Homo sapiens_hsa042700.48232603
111Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.47259531
112Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.46424241
113mTOR signaling pathway_Homo sapiens_hsa041500.46315559
114Dorso-ventral axis formation_Homo sapiens_hsa043200.46182754
115Prion diseases_Homo sapiens_hsa050200.46163668
116Adipocytokine signaling pathway_Homo sapiens_hsa049200.45263446
117B cell receptor signaling pathway_Homo sapiens_hsa046620.44555596
118African trypanosomiasis_Homo sapiens_hsa051430.44081485
119Hedgehog signaling pathway_Homo sapiens_hsa043400.43964347
120Chemokine signaling pathway_Homo sapiens_hsa040620.43084532
121Ras signaling pathway_Homo sapiens_hsa040140.42696901
122Gap junction_Homo sapiens_hsa045400.41396462
123Antigen processing and presentation_Homo sapiens_hsa046120.41238637
124Estrogen signaling pathway_Homo sapiens_hsa049150.41146156

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