MURC

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein containing two coiled-coil regions. The encoded protein promotes Rho/ROCK (Rho-kinase) signaling in cardiac muscles cells, and may facilitate myofibrillar organization. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sarcomere organization (GO:0045214)8.86919354
2regulation of skeletal muscle contraction (GO:0014819)8.66266982
3actin-mediated cell contraction (GO:0070252)8.61080169
4plasma membrane repair (GO:0001778)8.23272839
5negative regulation of potassium ion transmembrane transporter activity (GO:1901017)8.14794360
6skeletal muscle contraction (GO:0003009)7.80639197
7sarcoplasmic reticulum calcium ion transport (GO:0070296)7.65259734
8myofibril assembly (GO:0030239)7.28866863
9cardiac myofibril assembly (GO:0055003)7.12269280
10positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)7.10234482
11negative regulation of potassium ion transmembrane transport (GO:1901380)6.90167630
12regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)6.50229737
13actin filament-based movement (GO:0030048)6.47954791
14striated muscle contraction (GO:0006941)6.34578127
15response to stimulus involved in regulation of muscle adaptation (GO:0014874)6.27028178
16cardiac muscle contraction (GO:0060048)5.91223528
17actomyosin structure organization (GO:0031032)5.83000254
18regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)5.79186557
19regulation of relaxation of muscle (GO:1901077)5.65784387
20regulation of cell communication by electrical coupling (GO:0010649)5.63278418
21regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO5.59127922
22response to inactivity (GO:0014854)5.52079691
23cardiac muscle cell development (GO:0055013)5.41497832
24tricarboxylic acid cycle (GO:0006099)5.28782210
25regulation of sarcomere organization (GO:0060297)5.26095578
26regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)5.18968846
27cardiac cell development (GO:0055006)5.07625542
28regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)5.04473983
29regulation of actin filament-based movement (GO:1903115)5.04022530
30skeletal muscle adaptation (GO:0043501)5.03377963
31carnitine shuttle (GO:0006853)5.00264047
32skeletal muscle fiber development (GO:0048741)4.89639236
33regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)4.88755772
34striated muscle atrophy (GO:0014891)4.86117150
35skeletal muscle tissue development (GO:0007519)4.80847557
36muscle contraction (GO:0006936)4.78288822
37regulation of acyl-CoA biosynthetic process (GO:0050812)4.71599114
38regulation of striated muscle contraction (GO:0006942)4.71572762
39creatine metabolic process (GO:0006600)4.51646811
40ventricular cardiac muscle cell action potential (GO:0086005)4.47647865
41positive regulation of myotube differentiation (GO:0010831)4.47397799
42cardiac muscle hypertrophy (GO:0003300)4.45756022
43cardiac muscle tissue morphogenesis (GO:0055008)4.37608324
44muscle system process (GO:0003012)4.37088332
45response to muscle activity (GO:0014850)4.36599029
46regulation of membrane repolarization (GO:0060306)4.33286662
47striated muscle hypertrophy (GO:0014897)4.32213413
48muscle fiber development (GO:0048747)4.31728945
49regulation of cofactor metabolic process (GO:0051193)4.31274112
50regulation of coenzyme metabolic process (GO:0051196)4.31274112
51striated muscle adaptation (GO:0014888)4.29048380
52fatty acid transmembrane transport (GO:1902001)4.27880116
53striated muscle cell development (GO:0055002)4.26696574
54myotube cell development (GO:0014904)4.25546582
55heart contraction (GO:0060047)4.19277721
56heart process (GO:0003015)4.19277721
57muscle tissue morphogenesis (GO:0060415)4.18513071
58muscle atrophy (GO:0014889)4.16640531
59muscle cell fate commitment (GO:0042693)4.13395412
60muscle cell cellular homeostasis (GO:0046716)4.12409367
61glucan biosynthetic process (GO:0009250)4.12034592
62adult heart development (GO:0007512)4.10649951
63heart trabecula formation (GO:0060347)4.06019372
64negative regulation of protein localization to cell surface (GO:2000009)3.94329325
65bundle of His cell to Purkinje myocyte communication (GO:0086069)3.90073616
66myotube differentiation (GO:0014902)3.79417479
67muscle hypertrophy (GO:0014896)3.79249597
68muscle cell development (GO:0055001)3.70570582
69positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.70552305
70ventricular cardiac muscle tissue morphogenesis (GO:0055010)3.70130908
71negative regulation of potassium ion transport (GO:0043267)3.68909360
72skeletal muscle tissue regeneration (GO:0043403)3.68747274
73regulation of calcium ion transmembrane transporter activity (GO:1901019)3.68135258
74regulation of calcium ion transmembrane transport (GO:1903169)3.68135258
75carnitine transmembrane transport (GO:1902603)3.64476353
76cellular polysaccharide catabolic process (GO:0044247)3.54049161
77muscle adaptation (GO:0043500)3.53549490
78syncytium formation by plasma membrane fusion (GO:0000768)3.51629527
79regulation of skeletal muscle cell differentiation (GO:2001014)3.51551268
80glycogen catabolic process (GO:0005980)3.50614815
81regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.50347822
82negative regulation of calcium ion transmembrane transport (GO:1903170)3.49057532
83negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.49057532
84regulation of sulfur metabolic process (GO:0042762)3.46707141
85cell communication involved in cardiac conduction (GO:0086065)3.45051303
86response to activity (GO:0014823)3.42501855
87striated muscle tissue development (GO:0014706)3.39521451
88regulation of ATP catabolic process (GO:1903289)3.38361741
89regulation of ATPase activity (GO:0043462)3.38361741
90neuromuscular synaptic transmission (GO:0007274)3.37835384
91NADH metabolic process (GO:0006734)3.36157208
92regulation of the force of heart contraction (GO:0002026)3.35662018
93regulation of cardiac muscle contraction (GO:0055117)3.35244761
94regulation of muscle system process (GO:0090257)3.34366207
95mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.32217765
96myoblast fusion (GO:0007520)3.31602600
97negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.30691578
98carnitine transport (GO:0015879)3.30313289
99amino-acid betaine transport (GO:0015838)3.30313289
100cardiac muscle cell action potential (GO:0086001)3.27488133
101mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.27076046
102positive regulation of myoblast differentiation (GO:0045663)3.26731173
103regulation of myoblast differentiation (GO:0045661)3.26687819
104* muscle organ development (GO:0007517)3.26553112
105glucan catabolic process (GO:0009251)3.26045776
106regulation of muscle contraction (GO:0006937)3.25237099
107cardiac muscle adaptation (GO:0014887)3.24035392
108cardiac muscle hypertrophy in response to stress (GO:0014898)3.24035392
109muscle hypertrophy in response to stress (GO:0003299)3.24035392
110* muscle structure development (GO:0061061)3.23986076
111cardiac muscle cell action potential involved in contraction (GO:0086002)3.23140026
112regulation of sequestering of triglyceride (GO:0010889)3.23126069
113glycogen biosynthetic process (GO:0005978)3.22562339
114membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.18490160
115polysaccharide catabolic process (GO:0000272)3.17619207
116glycogen metabolic process (GO:0005977)3.13397851
117positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.09604579
118regulation of potassium ion transmembrane transporter activity (GO:1901016)3.08885301
119glucan metabolic process (GO:0044042)3.05801729
120muscle filament sliding (GO:0030049)10.3981325
121actin-myosin filament sliding (GO:0033275)10.3981325

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.60766312
2EP300_21415370_ChIP-Seq_HL-1_Mouse4.11122581
3ESR1_20079471_ChIP-ChIP_T-47D_Human3.98141864
4TBX20_22328084_ChIP-Seq_HEART_Mouse3.84039938
5TBX20_22080862_ChIP-Seq_HEART_Mouse3.84039938
6TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse3.82215886
7ESRRB_18555785_ChIP-Seq_MESCs_Mouse3.68937006
8BP1_19119308_ChIP-ChIP_Hs578T_Human3.31968511
9MEF2A_21415370_ChIP-Seq_HL-1_Mouse3.11986271
10RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.04920989
11* RARG_19884340_ChIP-ChIP_MEFs_Mouse3.02754618
12ZNF263_19887448_ChIP-Seq_K562_Human2.98794043
13GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.58850806
14GBX2_23144817_ChIP-Seq_PC3_Human2.54575319
15IGF1R_20145208_ChIP-Seq_DFB_Human2.45148265
16RBPJ_22232070_ChIP-Seq_NCS_Mouse2.33230991
17CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.23924739
18CDX2_19796622_ChIP-Seq_MESCs_Mouse2.22503557
19GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.17731942
20GATA4_21415370_ChIP-Seq_HL-1_Mouse2.17496833
21ZNF652_21678463_ChIP-ChIP_ZR75-1_Human2.15921835
22PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.08303433
23THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.06747766
24TRIM28_21343339_ChIP-Seq_HEK293_Human1.98455587
25EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.96316530
26VDR_22108803_ChIP-Seq_LS180_Human1.95658349
27CLOCK_20551151_ChIP-Seq_293T_Human1.89907034
28TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.89050576
29ESR2_21235772_ChIP-Seq_MCF-7_Human1.84446180
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.74950886
31NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.74898952
32CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.73942077
33FLI1_27457419_Chip-Seq_LIVER_Mouse1.71016110
34SUZ12_27294783_Chip-Seq_NPCs_Mouse1.68556515
35* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.67891871
36EZH2_22144423_ChIP-Seq_EOC_Human1.66412307
37NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.62632469
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.62114268
39PCGF2_27294783_Chip-Seq_ESCs_Mouse1.62113932
40EZH2_27294783_Chip-Seq_NPCs_Mouse1.61944069
41CBX2_27304074_Chip-Seq_ESCs_Mouse1.59968643
42ZNF274_21170338_ChIP-Seq_K562_Hela1.55003265
43CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.52651354
44CRX_20693478_ChIP-Seq_RETINA_Mouse1.49904684
45POU3F2_20337985_ChIP-ChIP_501MEL_Human1.48887473
46EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.44511034
47FUS_26573619_Chip-Seq_HEK293_Human1.43901235
48CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.43640819
49ESR1_21235772_ChIP-Seq_MCF-7_Human1.43619695
50PCGF2_27294783_Chip-Seq_NPCs_Mouse1.41902305
51SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.39565370
52NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.38936225
53AR_21572438_ChIP-Seq_LNCaP_Human1.38285333
54PPAR_26484153_Chip-Seq_NCI-H1993_Human1.37276653
55PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.35849449
56BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.33895839
57OCT4_21477851_ChIP-Seq_ESCs_Mouse1.33592192
58CTCF_27219007_Chip-Seq_Bcells_Human1.32251916
59KLF5_20875108_ChIP-Seq_MESCs_Mouse1.31748207
60BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.31210103
61* SMAD4_21799915_ChIP-Seq_A2780_Human1.30925763
62E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.28515085
63TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.28163758
64TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.28101426
65NFE2_27457419_Chip-Seq_LIVER_Mouse1.28031844
66ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.27704778
67SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.26148679
68KDM2B_26808549_Chip-Seq_DND41_Human1.26108766
69KDM2B_26808549_Chip-Seq_SUP-B15_Human1.26002031
70EZH2_27304074_Chip-Seq_ESCs_Mouse1.24999093
71ER_23166858_ChIP-Seq_MCF-7_Human1.21089988
72ATF3_27146783_Chip-Seq_COLON_Human1.20736988
73SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.20670380
74TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.19964336
75SALL1_21062744_ChIP-ChIP_HESCs_Human1.19157728
76WT1_19549856_ChIP-ChIP_CCG9911_Human1.18922980
77ZFP281_18757296_ChIP-ChIP_E14_Mouse1.18064064
78NR3C1_21868756_ChIP-Seq_MCF10A_Human1.17609067
79SMC3_22415368_ChIP-Seq_MEFs_Mouse1.16763648
80PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.15868250
81IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.15461680
82CBP_20019798_ChIP-Seq_JUKART_Human1.15461680
83* CJUN_26792858_Chip-Seq_BT549_Human1.15461616
84WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.13871905
85RACK7_27058665_Chip-Seq_MCF-7_Human1.13038594
86SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12815874
87SMC1_22415368_ChIP-Seq_MEFs_Mouse1.10911707
88SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.10744404
89* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.10286043
90KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.09873201
91P53_22387025_ChIP-Seq_ESCs_Mouse1.09182682
92P53_22127205_ChIP-Seq_FIBROBLAST_Human1.08663698
93* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.08110923
94ELK3_25401928_ChIP-Seq_HUVEC_Human1.07254181
95SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.07089503
96* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.06633952
97ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.06149037
98NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.06049677
99DROSHA_22980978_ChIP-Seq_HELA_Human1.05237073
100SOX2_19829295_ChIP-Seq_ESCs_Human1.04612449
101NANOG_19829295_ChIP-Seq_ESCs_Human1.04612449
102TAF15_26573619_Chip-Seq_HEK293_Human1.04025352
103E2F1_18555785_Chip-Seq_ESCs_Mouse1.03570895
104P300_27058665_Chip-Seq_ZR-75-30cells_Human1.03560863
105TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.02798766
106PIAS1_25552417_ChIP-Seq_VCAP_Human1.02324109
107* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02294376
108CTCF_21964334_ChIP-Seq_BJAB-B_Human0.99308811
109SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.98412094
110STAT3_1855785_ChIP-Seq_MESCs_Mouse0.97892906
111CTCF_21964334_Chip-Seq_Bcells_Human0.97862989
112EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.97843502
113HIF1A_21447827_ChIP-Seq_MCF-7_Human0.97684766
114TP63_22573176_ChIP-Seq_HFKS_Human0.97239341
115SMAD3_21741376_ChIP-Seq_EPCs_Human0.97185750
116* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.97017265
117UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.96634699
118FOXH1_21741376_ChIP-Seq_ESCs_Human0.96322684
119CTBP2_25329375_ChIP-Seq_LNCAP_Human0.95690154
120EZH2_18974828_ChIP-Seq_MESCs_Mouse0.95329641
121RNF2_18974828_ChIP-Seq_MESCs_Mouse0.95329641
122FLI1_21867929_ChIP-Seq_TH2_Mouse0.95164797
123* P300_19829295_ChIP-Seq_ESCs_Human0.95023207
124RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.94564825
125TCF4_23295773_ChIP-Seq_U87_Human0.94431848
126RUNX1_27514584_Chip-Seq_MCF-7_Human0.94225104
127* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.93618099
128* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93609316
129LXR_22292898_ChIP-Seq_THP-1_Human0.93477309
130ISL1_27105846_Chip-Seq_CPCs_Mouse0.93199872
131AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.92603746
132TBL1_22424771_ChIP-Seq_293T_Human0.92058924
133UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.91399035
134EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.91051120
135GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.90140266
136STAT3_23295773_ChIP-Seq_U87_Human0.89849710
137NANOG_18555785_Chip-Seq_ESCs_Mouse0.89838777
138CTNNB1_20460455_ChIP-Seq_HCT116_Human0.89795472
139NRF2_20460467_ChIP-Seq_MEFs_Mouse0.89767724
140NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.89767724
141GATA2_21666600_ChIP-Seq_HMVEC_Human0.88919267
142PPARA_22158963_ChIP-Seq_LIVER_Mouse0.88344503
143OCT4_20526341_ChIP-Seq_ESCs_Human0.87090318
144TP53_23651856_ChIP-Seq_MEFs_Mouse0.86191602
145GATA1_19941826_ChIP-Seq_K562_Human0.86156973
146SOX9_24532713_ChIP-Seq_HFSC_Mouse0.83572603
147P63_26484246_Chip-Seq_KERATINOCYTES_Human0.81590590
148KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.80967610
149EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.80749743
150LXR_22158963_ChIP-Seq_LIVER_Mouse0.80747045
151SOX2_21211035_ChIP-Seq_LN229_Gbm0.80634133
152HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.80348198
153TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.79846058
154CREB1_26743006_Chip-Seq_LNCaP_Human0.79349782
155NR3C1_23031785_ChIP-Seq_PC12_Mouse0.79203404
156SA1_27219007_Chip-Seq_Bcells_Human0.78741403
157SMAD3_21741376_ChIP-Seq_HESCs_Human0.78185576
158FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.77707462
159EZH2_27294783_Chip-Seq_ESCs_Mouse0.77440837
160KDM2B_26808549_Chip-Seq_K562_Human0.76818037
161DNAJC2_21179169_ChIP-ChIP_NT2_Human0.76689096
162TDRD3_21172665_ChIP-Seq_MCF-7_Human0.76384496
163NFIB_24661679_ChIP-Seq_LUNG_Mouse0.75686342
164TP53_22127205_ChIP-Seq_IMR90_Human0.75226575
165* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.75196919
166FOXA2_19822575_ChIP-Seq_HepG2_Human0.74696650
167PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.73711807

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000751_myopathy5.93352765
2MP0002837_dystrophic_cardiac_calcinosis5.71043557
3MP0003646_muscle_fatigue5.42217589
4MP0000749_muscle_degeneration5.39702572
5MP0004084_abnormal_cardiac_muscle4.44456912
6MP0004145_abnormal_muscle_electrophysio4.39333587
7MP0004036_abnormal_muscle_relaxation3.98783869
8MP0004215_abnormal_myocardial_fiber3.74130524
9MP0000750_abnormal_muscle_regeneration3.62143110
10MP0004087_abnormal_muscle_fiber3.56397906
11MP0002106_abnormal_muscle_physiology3.44313323
12MP0005330_cardiomyopathy3.40564122
13MP0000747_muscle_weakness3.28808911
14MP0000759_abnormal_skeletal_muscle3.00176369
15MP0002269_muscular_atrophy2.99212952
16MP0005620_abnormal_muscle_contractility2.86766637
17MP0005369_muscle_phenotype2.85927542
18MP0004130_abnormal_muscle_cell2.62876821
19MP0002972_abnormal_cardiac_muscle2.55217314
20MP0004233_abnormal_muscle_weight2.29361212
21MP0010630_abnormal_cardiac_muscle2.27204337
22MP0004484_altered_response_of2.20128025
23MP0003137_abnormal_impulse_conducting2.19052448
24MP0000733_abnormal_muscle_development2.12721848
25MP0008775_abnormal_heart_ventricle2.05546575
26MP0003950_abnormal_plasma_membrane2.05445442
27MP0001544_abnormal_cardiovascular_syste1.99132756
28MP0005385_cardiovascular_system_phenoty1.99132756
29MP0006138_congestive_heart_failure1.72261389
30MP0002108_abnormal_muscle_morphology1.66514160
31MP0003221_abnormal_cardiomyocyte_apopto1.64863630
32MP0006036_abnormal_mitochondrial_physio1.60819674
33MP0002332_abnormal_exercise_endurance1.60370536
34MP0003828_pulmonary_edema1.54895434
35MP0004085_abnormal_heartbeat1.42874649
36MP0004510_myositis1.41953108
37MP0005666_abnormal_adipose_tissue1.31961935
38MP0002127_abnormal_cardiovascular_syste1.22445819
39MP0004185_abnormal_adipocyte_glucose1.13046469
40MP0002234_abnormal_pharynx_morphology1.08937517
41MP0002971_abnormal_brown_adipose1.04271482
42MP0005375_adipose_tissue_phenotype1.01250936
43MP0004270_analgesia1.00545161
44MP0001661_extended_life_span0.99731678
45MP0000013_abnormal_adipose_tissue0.99693471
46MP0000266_abnormal_heart_morphology0.97542842
47MP0000372_irregular_coat_pigmentation0.95949392
48MP0005670_abnormal_white_adipose0.95586521
49MP0003567_abnormal_fetal_cardiomyocyte0.94636708
50MP0003279_aneurysm0.92092144
51MP0008438_abnormal_cutaneous_collagen0.91487118
52MP0005266_abnormal_metabolism0.88925279
53MP0003705_abnormal_hypodermis_morpholog0.87555926
54MP0006035_abnormal_mitochondrial_morpho0.86860319
55MP0005623_abnormal_meninges_morphology0.86778434
56MP0000343_altered_response_to0.84989597
57MP0002822_catalepsy0.80400175
58MP0005165_increased_susceptibility_to0.78259834
59MP0000003_abnormal_adipose_tissue0.72597051
60MP0005275_abnormal_skin_tensile0.67456449
61MP0006276_abnormal_autonomic_nervous0.67035395
62MP0002128_abnormal_blood_circulation0.65466921
63MP0001299_abnormal_eye_distance/0.64987644
64MP0002734_abnormal_mechanical_nocicepti0.64249218
65MP0004142_abnormal_muscle_tone0.62502306
66MP0010368_abnormal_lymphatic_system0.61854063
67MP0003566_abnormal_cell_adhesion0.61467619
68MP0003806_abnormal_nucleotide_metabolis0.59276760
69MP0009780_abnormal_chondrocyte_physiolo0.57613570
70MP0000767_abnormal_smooth_muscle0.55381346
71MP0003879_abnormal_hair_cell0.53834767
72MP0004043_abnormal_pH_regulation0.49448289
73MP0000230_abnormal_systemic_arterial0.48192302
74MP0003045_fibrosis0.45380329
75MP0005503_abnormal_tendon_morphology0.44210154
76MP0008961_abnormal_basal_metabolism0.43267026
77MP0004147_increased_porphyrin_level0.42312683
78MP0001879_abnormal_lymphatic_vessel0.41701109
79MP0002078_abnormal_glucose_homeostasis0.40659298
80MP0004272_abnormal_basement_membrane0.39498069
81MP0005319_abnormal_enzyme/_coenzyme0.38954893
82MP0008789_abnormal_olfactory_epithelium0.38331444
83MP0002638_abnormal_pupillary_reflex0.38160967
84MP0002925_abnormal_cardiovascular_devel0.37994153
85MP0002877_abnormal_melanocyte_morpholog0.37584120
86MP0003948_abnormal_gas_homeostasis0.36727106
87MP0002184_abnormal_innervation0.36126669
88MP0001943_abnormal_respiration0.35651915
89MP0005423_abnormal_somatic_nervous0.35361933
90MP0009384_cardiac_valve_regurgitation0.34724288
91MP0003136_yellow_coat_color0.33977041
92MP0002909_abnormal_adrenal_gland0.33591422
93MP0009672_abnormal_birth_weight0.32686115
94MP0009250_abnormal_appendicular_skeleto0.32232363
95MP0005187_abnormal_penis_morphology0.32024780
96MP0001614_abnormal_blood_vessel0.31330768
97MP0000762_abnormal_tongue_morphology0.31203695
98MP0005334_abnormal_fat_pad0.30841576
99MP0001984_abnormal_olfaction0.29676543
100MP0001784_abnormal_fluid_regulation0.29670632
101MP0002067_abnormal_sensory_capabilities0.28399705
102MP0003941_abnormal_skin_development0.28078813
103MP0001485_abnormal_pinna_reflex0.27536899
104MP0000534_abnormal_ureter_morphology0.27074606
105MP0002066_abnormal_motor_capabilities/c0.26916205
106MP0001346_abnormal_lacrimal_gland0.26823314
107MP0005452_abnormal_adipose_tissue0.26709981
108MP0002896_abnormal_bone_mineralization0.25969776
109MP0003385_abnormal_body_wall0.25479375
110MP0005451_abnormal_body_composition0.25215822
111MP0001529_abnormal_vocalization0.24747872
112MP0002249_abnormal_larynx_morphology0.24103916
113MP0009115_abnormal_fat_cell0.23558972
114MP0002081_perinatal_lethality0.22933359
115MP0002752_abnormal_somatic_nervous0.22202058
116MP0003755_abnormal_palate_morphology0.22173049
117MP0005376_homeostasis/metabolism_phenot0.21779493
118MP0001958_emphysema0.21716396
119MP0010030_abnormal_orbit_morphology0.21368400
120MP0008569_lethality_at_weaning0.20827463
121MP0004134_abnormal_chest_morphology0.20161349
122MP0003984_embryonic_growth_retardation0.19661694
123MP0002088_abnormal_embryonic_growth/wei0.18865784
124MP0002114_abnormal_axial_skeleton0.18115252
125MP0003091_abnormal_cell_migration0.17932601
126MP0003959_abnormal_lean_body0.17766674

Predicted human phenotypes

RankGene SetZ-score
1Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)7.01466203
2Muscle fiber inclusion bodies (HP:0100299)6.99644554
3Exercise-induced myalgia (HP:0003738)6.70068134
4Calf muscle hypertrophy (HP:0008981)6.67006165
5Muscle hypertrophy of the lower extremities (HP:0008968)6.49597813
6Nemaline bodies (HP:0003798)6.41270022
7Exercise-induced muscle cramps (HP:0003710)6.23263065
8Muscle fiber splitting (HP:0003555)5.88459296
9Type 1 muscle fiber predominance (HP:0003803)5.83386585
10Distal arthrogryposis (HP:0005684)5.57239999
11Sudden death (HP:0001699)5.56319296
12Abnormality of the calf musculature (HP:0001430)5.41585092
13Hyporeflexia of lower limbs (HP:0002600)5.30422753
14Difficulty running (HP:0009046)5.04678352
15EMG: myopathic abnormalities (HP:0003458)4.80430511
16Round ear (HP:0100830)4.72854431
17Myoglobinuria (HP:0002913)4.43937731
18Increased connective tissue (HP:0009025)4.31225645
19Ventricular tachycardia (HP:0004756)4.30571309
20Ulnar deviation of the wrist (HP:0003049)4.16896350
21Myopathic facies (HP:0002058)4.14558301
22Abnormality of the left ventricular outflow tract (HP:0011103)3.97953192
23Subaortic stenosis (HP:0001682)3.97953192
24Difficulty climbing stairs (HP:0003551)3.95880585
25Malignant hyperthermia (HP:0002047)3.67124122
26Myotonia (HP:0002486)3.60822308
27Calcaneovalgus deformity (HP:0001848)3.60501183
28Atrial fibrillation (HP:0005110)3.59381152
29Fetal akinesia sequence (HP:0001989)3.58227900
30Lipoatrophy (HP:0100578)3.52524075
31Rhabdomyolysis (HP:0003201)3.51899891
32Abnormality of skeletal muscle fiber size (HP:0012084)3.51705257
33Right ventricular cardiomyopathy (HP:0011663)3.49705009
34Primary atrial arrhythmia (HP:0001692)3.34893302
35Neck muscle weakness (HP:0000467)3.30919626
36Increased variability in muscle fiber diameter (HP:0003557)3.28236443
37Deformed tarsal bones (HP:0008119)3.27496329
38Absent phalangeal crease (HP:0006109)3.24888933
39Supraventricular tachycardia (HP:0004755)3.22176724
40Gowers sign (HP:0003391)3.21325802
41Asymmetric septal hypertrophy (HP:0001670)3.20623520
42Supraventricular arrhythmia (HP:0005115)3.15513634
43Abnormality of the neuromuscular junction (HP:0003398)3.13710448
44Fatigable weakness (HP:0003473)3.13710448
45Muscle stiffness (HP:0003552)3.08519714
46Dilated cardiomyopathy (HP:0001644)3.07080882
47Popliteal pterygium (HP:0009756)2.94951007
48Bundle branch block (HP:0011710)2.92206373
49Weak cry (HP:0001612)2.89553936
50Mildly elevated creatine phosphokinase (HP:0008180)2.85494229
51Areflexia of lower limbs (HP:0002522)2.78876777
52Bulbar palsy (HP:0001283)2.74077720
53Distal lower limb muscle weakness (HP:0009053)2.71748056
54Generalized muscle weakness (HP:0003324)2.71169488
55Syncope (HP:0001279)2.69511371
56Abnormal finger flexion creases (HP:0006143)2.68060183
57Prolonged QT interval (HP:0001657)2.64686839
58Palpitations (HP:0001962)2.62757773
59Hypoplastic ischia (HP:0003175)2.59923057
60Limb-girdle muscle atrophy (HP:0003797)2.56890097
61Ventricular arrhythmia (HP:0004308)2.52964604
62Frequent falls (HP:0002359)2.49830932
63Type 2 muscle fiber atrophy (HP:0003554)2.48097589
64Hip contracture (HP:0003273)2.47932798
65Distal lower limb amyotrophy (HP:0008944)2.47288770
66Aplasia of the musculature (HP:0100854)2.45572429
67Rimmed vacuoles (HP:0003805)2.45540691
68Heart block (HP:0012722)2.45176684
69Abnormality of placental membranes (HP:0011409)2.43328201
70Amniotic constriction ring (HP:0009775)2.43328201
71Scapular winging (HP:0003691)2.43120296
72EMG: neuropathic changes (HP:0003445)2.41870743
73Abnormal atrioventricular conduction (HP:0005150)2.37858276
74Long clavicles (HP:0000890)2.33604260
75Atrioventricular block (HP:0001678)2.29508262
76Facial diplegia (HP:0001349)2.28393222
77Muscular dystrophy (HP:0003560)2.26258463
78Abnormality of the ischium (HP:0003174)2.25065917
79Muscle fiber atrophy (HP:0100295)2.23106998
80Centrally nucleated skeletal muscle fibers (HP:0003687)2.22950447
81Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.20444978
82Proximal amyotrophy (HP:0007126)2.15167233
83Easy fatigability (HP:0003388)2.14699442
84Spinal rigidity (HP:0003306)2.14511742
85Abnormality of the calcaneus (HP:0008364)2.13523202
86Metatarsus adductus (HP:0001840)2.10497997
87Limb-girdle muscle weakness (HP:0003325)2.05073854
88Testicular atrophy (HP:0000029)2.03772173
89Nonprogressive disorder (HP:0003680)1.99870562
90Abnormality of the musculature of the pelvis (HP:0001469)1.99646869
91Abnormality of the hip-girdle musculature (HP:0001445)1.99646869
92Hyperkalemia (HP:0002153)1.98939643
93Waddling gait (HP:0002515)1.98165402
94Respiratory insufficiency due to muscle weakness (HP:0002747)1.95428543
95Hypoplastic heart (HP:0001961)1.95361433
96Slender build (HP:0001533)1.94680578
97Progressive muscle weakness (HP:0003323)1.92238188
98Pelvic girdle muscle weakness (HP:0003749)1.91521766
99Shoulder girdle muscle weakness (HP:0003547)1.90422392
100Abnormality of the shoulder girdle musculature (HP:0001435)1.90069257
101Lower limb amyotrophy (HP:0007210)1.89499232
102Left ventricular hypertrophy (HP:0001712)1.86522053
103Ventricular fibrillation (HP:0001663)1.82463214
104Abnormal EKG (HP:0003115)1.80341899
105Abnormality of the foot musculature (HP:0001436)1.80152049
106Limited hip movement (HP:0008800)1.77890438
107Thin ribs (HP:0000883)1.75310181
108Breech presentation (HP:0001623)1.67717568
109Ulnar deviation of finger (HP:0009465)1.65725349
110Foot dorsiflexor weakness (HP:0009027)1.61923025
111Pterygium (HP:0001059)1.51621746
112Ulnar deviation of the hand or of fingers of the hand (HP:0001193)1.51183905
113Exercise intolerance (HP:0003546)1.49529620
114Steppage gait (HP:0003376)1.49251762

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OBSCN6.54564380
2TTN6.36902870
3PHKG14.48376610
4PHKG24.48376610
5MUSK3.63477942
6TRIB33.23086235
7PDK43.05394667
8PDK33.05394667
9DMPK2.75818934
10PIK3CG2.71205627
11PKN22.24697509
12NEK12.10230971
13LMTK22.05854706
14MARK12.01386662
15PIK3CA2.00791991
16PINK11.99322391
17PDK21.90442977
18MYLK1.86026790
19NME11.77598966
20BCKDK1.72830281
21CCNB11.66822322
22MAP2K31.50342551
23MAP3K71.46474265
24MAPK121.36379633
25MOS1.21691096
26STK241.19865015
27ILK1.18893761
28TIE11.18795610
29ZAK0.95866710
30TRPM70.94820465
31PAK30.94808608
32GRK70.91868709
33CAMK2D0.91065054
34EPHB10.90545180
35PRKD10.90025507
36MAPKAPK30.88507102
37ROCK10.86344120
38PRKAA10.84473974
39MAP3K50.78131090
40PRKAA20.77079557
41MAPK130.76115681
42EEF2K0.73015543
43RIPK10.71237532
44PDGFRA0.70595302
45AKT20.70054794
46NEK90.69359137
47MAP3K30.66442558
48ROCK20.65733208
49INSRR0.63688679
50PKN10.61439418
51MAP3K100.58539798
52MAP2K10.58215728
53ICK0.58175059
54MAPK40.52151837
55SIK10.51410537
56BMPR1B0.50302886
57MAP2K40.50164449
58CAMK2B0.49001330
59PRKACB0.47970283
60CAMK2G0.47293233
61PTK60.44252057
62CAMK2A0.44215338
63TNIK0.43024727
64MAP4K20.42350038
65STK38L0.42226242
66DAPK30.41905375
67CDK80.41505583
68CASK0.40523305
69CDC42BPA0.40011716
70WNK30.38440086
71CAMK40.37745292
72LIMK10.37312085
73WNK10.37226631
74SGK20.36038444
75PDPK10.35587307
76MAP2K60.35130795
77STK40.34680176
78MTOR0.34638238
79LATS20.33959943
80EPHB20.32306467
81FLT30.32047343
82MAPK110.32022625
83PTK2B0.30797358
84EPHA30.30672831
85LATS10.30608196
86PRKG10.30255827
87PRKACA0.29844558
88SGK30.29179293
89KDR0.29161141
90TGFBR20.26858470
91STK110.25581758
92MAPK70.25491218
93RPS6KA30.25379805
94STK380.24776560
95PDK10.23758318
96SGK10.22680455
97RPS6KL10.22555570
98RPS6KC10.22555570
99WNK40.21833235
100NME20.21715497
101PNCK0.20731929
102MAPK100.20681553
103PRKACG0.20538513
104RPS6KA10.19436009
105LRRK20.19329955
106DDR20.18903180
107FER0.18619648
108RPS6KB10.17223962
109SGK4940.17202084
110SGK2230.17202084
111OXSR10.17174046
112PAK60.16353322
113FRK0.16244220
114RPS6KA60.16022594
115MAP3K40.15607191
116MAP3K110.15181895
117PBK0.14370633
118DYRK1B0.14071523
119CAMK10.14016091
120PRKCH0.13629488
121CSNK1D0.13317249
122TAOK20.12601677
123MARK20.11629869
124PRKCE0.11529489
125PAK40.11525305
126PRKDC0.11507197
127ERBB30.10745803
128PRKD30.10189850
129PLK20.10075117
130CSNK1G20.09474940
131MAPK80.07602383
132GSK3B0.06932867
133KSR10.06519065
134NLK0.06035367
135DYRK1A0.05789680
136MAPK90.05663973
137CSNK1E0.05071810
138DAPK20.04923395

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000205.35881038
2Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054104.46419802
3Cardiac muscle contraction_Homo sapiens_hsa042604.32643777
4Dilated cardiomyopathy_Homo sapiens_hsa054144.29582831
52-Oxocarboxylic acid metabolism_Homo sapiens_hsa012103.90096773
6Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054123.49207695
7Propanoate metabolism_Homo sapiens_hsa006402.88843458
8Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.75831962
9Parkinsons disease_Homo sapiens_hsa050122.67825096
10Oxidative phosphorylation_Homo sapiens_hsa001902.51543745
11Fatty acid degradation_Homo sapiens_hsa000712.38591810
12Carbon metabolism_Homo sapiens_hsa012002.27709915
13Alzheimers disease_Homo sapiens_hsa050102.08983423
14Viral myocarditis_Homo sapiens_hsa054161.97184319
15Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.93817759
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.92144464
17Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.89876714
18Fatty acid metabolism_Homo sapiens_hsa012121.82363992
19Pyruvate metabolism_Homo sapiens_hsa006201.54462008
20Huntingtons disease_Homo sapiens_hsa050161.53642627
21Starch and sucrose metabolism_Homo sapiens_hsa005001.45681555
22Glucagon signaling pathway_Homo sapiens_hsa049221.35999154
23Insulin signaling pathway_Homo sapiens_hsa049101.34670742
24Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.34314913
25Insulin resistance_Homo sapiens_hsa049311.31931732
26Oxytocin signaling pathway_Homo sapiens_hsa049211.21278456
27Adipocytokine signaling pathway_Homo sapiens_hsa049201.19002420
28Tight junction_Homo sapiens_hsa045301.16617164
29Focal adhesion_Homo sapiens_hsa045101.15452101
30Pentose phosphate pathway_Homo sapiens_hsa000301.14972482
31Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.14822207
32Biosynthesis of amino acids_Homo sapiens_hsa012301.08377520
33Nitrogen metabolism_Homo sapiens_hsa009101.06445487
34Butanoate metabolism_Homo sapiens_hsa006501.05744672
35cGMP-PKG signaling pathway_Homo sapiens_hsa040221.04801429
36AMPK signaling pathway_Homo sapiens_hsa041521.04202934
37Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.03474624
38Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.98908500
39Calcium signaling pathway_Homo sapiens_hsa040200.97669463
40Fatty acid elongation_Homo sapiens_hsa000620.95047770
41Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.94443502
42Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.92513409
43HIF-1 signaling pathway_Homo sapiens_hsa040660.85376567
44PPAR signaling pathway_Homo sapiens_hsa033200.79342284
45Arginine and proline metabolism_Homo sapiens_hsa003300.77739841
46Vascular smooth muscle contraction_Homo sapiens_hsa042700.77736206
47Circadian rhythm_Homo sapiens_hsa047100.76465018
48Phototransduction_Homo sapiens_hsa047440.69809904
49Galactose metabolism_Homo sapiens_hsa000520.68827783
50Salivary secretion_Homo sapiens_hsa049700.66731332
51ECM-receptor interaction_Homo sapiens_hsa045120.66059168
52Central carbon metabolism in cancer_Homo sapiens_hsa052300.66056272
53Adherens junction_Homo sapiens_hsa045200.65913075
54Longevity regulating pathway - mammal_Homo sapiens_hsa042110.62980854
55Lysine degradation_Homo sapiens_hsa003100.58712658
56Long-term potentiation_Homo sapiens_hsa047200.58433958
57Proteoglycans in cancer_Homo sapiens_hsa052050.56150728
58Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.53977439
59Arginine biosynthesis_Homo sapiens_hsa002200.53667465
60Fructose and mannose metabolism_Homo sapiens_hsa000510.50557849
61Fatty acid biosynthesis_Homo sapiens_hsa000610.49733433
62Type II diabetes mellitus_Homo sapiens_hsa049300.49173547
63Amoebiasis_Homo sapiens_hsa051460.48968597
64Regulation of actin cytoskeleton_Homo sapiens_hsa048100.48854148
65beta-Alanine metabolism_Homo sapiens_hsa004100.48829345
66mTOR signaling pathway_Homo sapiens_hsa041500.45374681
67Renin secretion_Homo sapiens_hsa049240.44844372
68Renal cell carcinoma_Homo sapiens_hsa052110.44584145
69Gastric acid secretion_Homo sapiens_hsa049710.44460294
70Thyroid hormone signaling pathway_Homo sapiens_hsa049190.44344095
71Leukocyte transendothelial migration_Homo sapiens_hsa046700.43435209
72Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.43023479
73Long-term depression_Homo sapiens_hsa047300.42687668
74FoxO signaling pathway_Homo sapiens_hsa040680.41836889
75Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.41437592
76Tryptophan metabolism_Homo sapiens_hsa003800.41279696
77Insulin secretion_Homo sapiens_hsa049110.36864683
78GnRH signaling pathway_Homo sapiens_hsa049120.36728880
79VEGF signaling pathway_Homo sapiens_hsa043700.36405252
80Amphetamine addiction_Homo sapiens_hsa050310.34687054
81Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.34400029
82MAPK signaling pathway_Homo sapiens_hsa040100.34178590
83Olfactory transduction_Homo sapiens_hsa047400.32334919
84Platelet activation_Homo sapiens_hsa046110.30342223
85Oocyte meiosis_Homo sapiens_hsa041140.30197828
86cAMP signaling pathway_Homo sapiens_hsa040240.29637114
87Regulation of autophagy_Homo sapiens_hsa041400.29570698
88Dopaminergic synapse_Homo sapiens_hsa047280.28009502
89Purine metabolism_Homo sapiens_hsa002300.25575996
90Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.24829643
91Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.24277204
92Peroxisome_Homo sapiens_hsa041460.24087168
93Axon guidance_Homo sapiens_hsa043600.22402758
94Aldosterone synthesis and secretion_Homo sapiens_hsa049250.20224925
95Phenylalanine metabolism_Homo sapiens_hsa003600.19917764
96AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.19888023
97Histidine metabolism_Homo sapiens_hsa003400.19320522
98GABAergic synapse_Homo sapiens_hsa047270.19286232
99Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.19149360
100Dorso-ventral axis formation_Homo sapiens_hsa043200.17920603
101Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.17307709
102Gap junction_Homo sapiens_hsa045400.16366496
103Cholinergic synapse_Homo sapiens_hsa047250.16086606
104Circadian entrainment_Homo sapiens_hsa047130.13757117
105Protein digestion and absorption_Homo sapiens_hsa049740.13563129
106Wnt signaling pathway_Homo sapiens_hsa043100.13089448
107Cysteine and methionine metabolism_Homo sapiens_hsa002700.11472774
108Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.10165438
109PI3K-Akt signaling pathway_Homo sapiens_hsa041510.10098142
110Metabolic pathways_Homo sapiens_hsa011000.09733374
111Ovarian steroidogenesis_Homo sapiens_hsa049130.09482960
112Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.09176461
113Melanoma_Homo sapiens_hsa052180.09146061
114Salmonella infection_Homo sapiens_hsa051320.07789132
115Notch signaling pathway_Homo sapiens_hsa043300.05825605
116Chronic myeloid leukemia_Homo sapiens_hsa052200.05401565
117Small cell lung cancer_Homo sapiens_hsa052220.04501633
118Melanogenesis_Homo sapiens_hsa049160.04211590
119Toxoplasmosis_Homo sapiens_hsa051450.03578657
120Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.02230033
121Pancreatic secretion_Homo sapiens_hsa049720.01058714
122Rap1 signaling pathway_Homo sapiens_hsa04015-0.0055637
123Glioma_Homo sapiens_hsa05214-0.0044197
124Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961-0.0037980

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