MUC15

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1oligosaccharide biosynthetic process (GO:0009312)8.87848568
2axoneme assembly (GO:0035082)8.47292483
3vitamin transmembrane transport (GO:0035461)6.81738702
4primary alcohol catabolic process (GO:0034310)6.62728300
5left/right pattern formation (GO:0060972)6.62261943
6long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)6.61231098
7fatty-acyl-CoA biosynthetic process (GO:0046949)6.55217881
8regulation of cilium movement (GO:0003352)6.54839202
9regulation of vascular endothelial growth factor signaling pathway (GO:1900746)6.43187251
10ectoderm development (GO:0007398)6.30759141
11acyl-CoA biosynthetic process (GO:0071616)6.24849451
12thioester biosynthetic process (GO:0035384)6.24849451
13lactation (GO:0007595)6.22905741
14regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)6.00420224
15ethanol metabolic process (GO:0006067)5.97017637
16mammary gland epithelial cell differentiation (GO:0060644)5.90063891
17pyrimidine-containing compound transmembrane transport (GO:0072531)5.77204067
18left/right axis specification (GO:0070986)5.58929736
19linoleic acid metabolic process (GO:0043651)5.53372610
20segment specification (GO:0007379)5.50050538
21alpha-linolenic acid metabolic process (GO:0036109)5.44524332
22secretion by tissue (GO:0032941)5.43464449
23long-chain fatty-acyl-CoA metabolic process (GO:0035336)5.36776652
24ventricular system development (GO:0021591)5.24512015
25microtubule bundle formation (GO:0001578)5.20760687
26type B pancreatic cell proliferation (GO:0044342)5.09762949
27diterpenoid biosynthetic process (GO:0016102)5.08231335
28regulation of sequestering of triglyceride (GO:0010889)5.01378624
29one-carbon compound transport (GO:0019755)5.01271052
30lung epithelium development (GO:0060428)5.00379899
31positive regulation of p38MAPK cascade (GO:1900745)4.94275725
32intraciliary transport (GO:0042073)4.93768197
33fatty-acyl-CoA metabolic process (GO:0035337)4.88449738
34desmosome organization (GO:0002934)4.76548301
35cilium organization (GO:0044782)4.72558148
36growth hormone receptor signaling pathway (GO:0060396)4.70579127
37ethanol oxidation (GO:0006069)4.65260425
38multicellular organismal water homeostasis (GO:0050891)4.63028775
39nucleoside transmembrane transport (GO:1901642)4.62105772
40negative regulation of humoral immune response (GO:0002921)4.60913873
41hemidesmosome assembly (GO:0031581)4.60342564
42cilium assembly (GO:0042384)4.58467491
43body fluid secretion (GO:0007589)4.56318991
44fatty acid transmembrane transport (GO:1902001)4.55395801
45carnitine shuttle (GO:0006853)4.54912938
46regulation of interleukin-5 production (GO:0032674)4.52748614
47biotin metabolic process (GO:0006768)4.37780014
48tooth mineralization (GO:0034505)4.35058972
49response to xenobiotic stimulus (GO:0009410)4.19773609
50embryonic process involved in female pregnancy (GO:0060136)4.04188212
51regulation of interleukin-13 production (GO:0032656)3.99864487
52cellular response to growth hormone stimulus (GO:0071378)3.98669911
53establishment of apical/basal cell polarity (GO:0035089)3.98653227
54water homeostasis (GO:0030104)3.97899563
55tolerance induction (GO:0002507)3.95709702
56excretion (GO:0007588)3.92373564
57glomerular epithelial cell development (GO:0072310)3.91102991
58regulation of apoptotic process involved in morphogenesis (GO:1902337)3.89630279
59protein localization to cilium (GO:0061512)3.86583433
60keratinization (GO:0031424)3.80390632
61regulation of triglyceride biosynthetic process (GO:0010866)3.78633212
62regulation of microtubule-based movement (GO:0060632)3.77206637
63terpenoid biosynthetic process (GO:0016114)3.76212813
64retinoic acid metabolic process (GO:0042573)3.75809048
65triglyceride biosynthetic process (GO:0019432)3.74858085
66negative regulation of fatty acid transport (GO:2000192)3.73582970
67polyol transport (GO:0015791)3.71559392
68phagocytosis, recognition (GO:0006910)3.69640704
69N-acetylneuraminate metabolic process (GO:0006054)3.69181294
70cellular component assembly involved in morphogenesis (GO:0010927)3.67168435
71thyroid hormone generation (GO:0006590)3.67042415
72establishment of tissue polarity (GO:0007164)3.65018213
73establishment of planar polarity (GO:0001736)3.65018213
74regulation of p38MAPK cascade (GO:1900744)3.62208199
75neutral lipid biosynthetic process (GO:0046460)3.60587643
76acylglycerol biosynthetic process (GO:0046463)3.60587643
77negative regulation of T cell differentiation in thymus (GO:0033085)3.59768063
78acetyl-CoA metabolic process (GO:0006084)3.58074873
79Golgi transport vesicle coating (GO:0048200)3.54366564
80COPI coating of Golgi vesicle (GO:0048205)3.54366564
81regulation of apoptotic cell clearance (GO:2000425)3.53253051
82nucleoside transport (GO:0015858)3.53091548
83microtubule-based movement (GO:0007018)3.52002699
84calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.51512861
85response to phenylpropanoid (GO:0080184)3.50640444
86proximal/distal pattern formation (GO:0009954)3.50537376
87cilium morphogenesis (GO:0060271)3.50027574
88negative regulation of immunoglobulin mediated immune response (GO:0002890)3.48749992
89negative regulation of B cell mediated immunity (GO:0002713)3.48749992
90establishment of monopolar cell polarity (GO:0061162)3.48040298
91establishment or maintenance of monopolar cell polarity (GO:0061339)3.48040298
92positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568)3.46756191
93primary alcohol metabolic process (GO:0034308)3.45521834
94regulation of triglyceride metabolic process (GO:0090207)3.44952711
95positive regulation of triglyceride metabolic process (GO:0090208)3.42664229
96nucleobase catabolic process (GO:0046113)3.41765836
97regulation of macrophage cytokine production (GO:0010935)3.40339533
98centriole assembly (GO:0098534)3.39554976
99negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.37621734
100copper ion transport (GO:0006825)3.37133807
101cell projection assembly (GO:0030031)3.36265271
102regulation of germinal center formation (GO:0002634)3.36227118
103carnitine transmembrane transport (GO:1902603)3.36088184
104retinol metabolic process (GO:0042572)3.33855224
105long-chain fatty acid transport (GO:0015909)3.33615060
106regulation of penile erection (GO:0060405)3.33603749
107lipid storage (GO:0019915)3.33259109
108carnitine metabolic process (GO:0009437)3.30722632
109sperm capacitation (GO:0048240)3.22702118
110negative regulation of smooth muscle cell migration (GO:0014912)3.22521722
111fatty acid transport (GO:0015908)3.14380614
112keratinocyte development (GO:0003334)3.13100302
113thyroid hormone metabolic process (GO:0042403)3.12019520
114negative regulation of keratinocyte proliferation (GO:0010839)3.11981396
115lateral sprouting from an epithelium (GO:0060601)3.11835730
116positive regulation of histone deacetylation (GO:0031065)3.11252059
117low-density lipoprotein particle clearance (GO:0034383)3.11165560
118carnitine transport (GO:0015879)3.10306688
119amino-acid betaine transport (GO:0015838)3.10306688
120regulation of clathrin-mediated endocytosis (GO:2000369)3.09390937
121positive regulation of sodium ion transmembrane transporter activity (GO:2000651)3.08840553
122lateral ventricle development (GO:0021670)3.05484081
123positive regulation of macrophage cytokine production (GO:0060907)3.05350937
124cytoplasmic microtubule organization (GO:0031122)3.02786340
125regulation of vasculogenesis (GO:2001212)3.00344240
126bundle of His cell to Purkinje myocyte communication (GO:0086069)3.00298947
127glutathione derivative metabolic process (GO:1901685)2.99540226
128glutathione derivative biosynthetic process (GO:1901687)2.99540226
129interferon-gamma secretion (GO:0072643)2.97693967
130L-ascorbic acid metabolic process (GO:0019852)2.95888301
131positive regulation of tolerance induction (GO:0002645)2.95767424
132regulation of complement activation (GO:0030449)2.93598652
133cellular response to vitamin D (GO:0071305)2.91194239
134renal absorption (GO:0070293)2.91091905
135pentose-phosphate shunt (GO:0006098)2.90949470
136coenzyme A biosynthetic process (GO:0015937)2.90614683
137positive regulation of smoothened signaling pathway (GO:0045880)2.87043906
138insulin-like growth factor receptor signaling pathway (GO:0048009)2.86307480
139regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.84642963
140triglyceride catabolic process (GO:0019433)2.81321417
141sodium ion homeostasis (GO:0055078)2.81164150
142positive regulation of triglyceride biosynthetic process (GO:0010867)2.79568263
143apical protein localization (GO:0045176)2.79565687
144regulation of protein activation cascade (GO:2000257)2.79532812
145acyl-CoA metabolic process (GO:0006637)2.77940663
146thioester metabolic process (GO:0035383)2.77940663
147regulation of water loss via skin (GO:0033561)2.76926460
148intracellular lipid transport (GO:0032365)2.76907120
149amino-acid betaine metabolic process (GO:0006577)2.74316026
150folic acid transport (GO:0015884)2.73702589
151seminiferous tubule development (GO:0072520)2.72617924
152molting cycle (GO:0042303)2.72516492
153hair cycle (GO:0042633)2.72516492
154cornea development in camera-type eye (GO:0061303)2.72455655
155mammary gland development (GO:0030879)2.70496862
156nucleoside diphosphate phosphorylation (GO:0006165)2.70236420
157dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.68306501
158oligosaccharide metabolic process (GO:0009311)2.68049239
159keratinocyte proliferation (GO:0043616)2.66591714
160regulation of toll-like receptor 4 signaling pathway (GO:0034143)2.66314970
161exogenous drug catabolic process (GO:0042738)2.66146828
162regulation of endothelial cell differentiation (GO:0045601)2.66064014
163iron ion import (GO:0097286)2.65163906
164surfactant homeostasis (GO:0043129)2.65027188
165progesterone metabolic process (GO:0042448)2.63957819
166valine metabolic process (GO:0006573)2.62942224
167phosphatidylcholine biosynthetic process (GO:0006656)2.62326691
168gland morphogenesis (GO:0022612)2.61654500
169negative regulation of cell fate specification (GO:0009996)2.61510859
170angiogenesis involved in wound healing (GO:0060055)2.59636410
171regulation of response to osmotic stress (GO:0047484)2.59226920
172negative regulation of complement activation (GO:0045916)2.58752832
173epidermis development (GO:0008544)2.58462599
174positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.57218299
175regulation of nephron tubule epithelial cell differentiation (GO:0072182)2.57172019
176androgen biosynthetic process (GO:0006702)2.56818471
177NADPH regeneration (GO:0006740)2.56709949
178epithelial cell differentiation involved in prostate gland development (GO:0060742)2.56085309
179zinc ion transport (GO:0006829)2.55416434
180transcytosis (GO:0045056)2.55062882
181keratinocyte differentiation (GO:0030216)2.54638763
182positive regulation of tissue remodeling (GO:0034105)2.53134732
183establishment of skin barrier (GO:0061436)2.52636930
184neutral lipid catabolic process (GO:0046461)2.52026467
185acylglycerol catabolic process (GO:0046464)2.52026467
186axonemal dynein complex assembly (GO:0070286)16.6673202
187cilium or flagellum-dependent cell motility (GO:0001539)14.5748853
188cilium movement (GO:0003341)12.4544133
189epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)11.5547288
190motile cilium assembly (GO:0044458)11.1843346
191epithelial cilium movement (GO:0003351)10.5669966
192pattern specification involved in kidney development (GO:0061004)10.5060801

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human7.21424516
2* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse5.13963159
3ESR1_21235772_ChIP-Seq_MCF-7_Human4.56358379
4ESR2_21235772_ChIP-Seq_MCF-7_Human3.89375302
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.87300352
6ZNF263_19887448_ChIP-Seq_K562_Human3.62245499
7TRIM28_21343339_ChIP-Seq_HEK293_Human3.28215077
8TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.03257011
9STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.75667514
10ZNF217_24962896_ChIP-Seq_MCF-7_Human2.55987805
11CLOCK_20551151_ChIP-Seq_293T_Human2.50597875
12PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.43687110
13RARG_19884340_ChIP-ChIP_MEFs_Mouse2.24728745
14CDX2_19796622_ChIP-Seq_MESCs_Mouse2.08373161
15SOX9_24532713_ChIP-Seq_HFSC_Mouse2.06488343
16TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.94755405
17DROSHA_22980978_ChIP-Seq_HELA_Human1.94143011
18CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.90184954
19PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.86822998
20FOXO3_23340844_ChIP-Seq_DLD1_Human1.85445504
21PPAR_26484153_Chip-Seq_NCI-H1993_Human1.84212377
22ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.78137031
23SOX2_20726797_ChIP-Seq_SW620_Human1.76948677
24TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.75890004
25ESR1_15608294_ChIP-ChIP_MCF-7_Human1.74841516
26AHR_22903824_ChIP-Seq_MCF-7_Human1.72613096
27FOXA2_19822575_ChIP-Seq_HepG2_Human1.72328040
28ESR1_20079471_ChIP-ChIP_T-47D_Human1.67986692
29NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.67492765
30ERG_21242973_ChIP-ChIP_JURKAT_Human1.64369162
31SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.58930126
32RUNX1_27514584_Chip-Seq_MCF-7_Human1.54965427
33SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.54608580
34VDR_22108803_ChIP-Seq_LS180_Human1.54460115
35KLF5_25053715_ChIP-Seq_YYC3_Human1.48053711
36RXR_22108803_ChIP-Seq_LS180_Human1.47039816
37LXR_22158963_ChIP-Seq_LIVER_Mouse1.46081248
38NR3C1_21868756_ChIP-Seq_MCF10A_Human1.44549838
39P63_26484246_Chip-Seq_KERATINOCYTES_Human1.44052650
40RXR_22158963_ChIP-Seq_LIVER_Mouse1.43385793
41RACK7_27058665_Chip-Seq_MCF-7_Human1.40431008
42FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.38954549
43ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.38553673
44FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.37574958
45NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.37289078
46TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.36446501
47SMAD3_21741376_ChIP-Seq_HESCs_Human1.34696783
48ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.31397154
49KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.31368510
50SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.28931140
51ARNT_22903824_ChIP-Seq_MCF-7_Human1.28581742
52EP300_21415370_ChIP-Seq_HL-1_Mouse1.27411806
53PIAS1_25552417_ChIP-Seq_VCAP_Human1.27180734
54GATA4_25053715_ChIP-Seq_YYC3_Human1.23023858
55BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.22357694
56EGR1_23403033_ChIP-Seq_LIVER_Mouse1.21806608
57TP53_18474530_ChIP-ChIP_U2OS_Human1.21665241
58SOX2_27498859_Chip-Seq_STOMACH_Mouse1.20875308
59PPARA_22158963_ChIP-Seq_LIVER_Mouse1.18942103
60GATA3_24758297_ChIP-Seq_MCF-7_Human1.18552259
61TP63_22573176_ChIP-Seq_HFKS_Human1.16455394
62ETV1_20927104_ChIP-Seq_GIST48_Human1.14840229
63PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.14146745
64CJUN_26792858_Chip-Seq_BT549_Human1.13788798
65CDX2_22108803_ChIP-Seq_LS180_Human1.12908157
66TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.11747259
67* FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.10395540
68* SMAD4_21799915_ChIP-Seq_A2780_Human1.10117817
69HIF1A_21447827_ChIP-Seq_MCF-7_Human1.10050220
70TP63_23658742_ChIP-Seq_EP156T_Human1.09335448
71AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.07788693
72TOP2B_26459242_ChIP-Seq_MCF-7_Human1.07432391
73TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.07370755
74SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.06620158
75ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.06411306
76SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.05511884
77SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.05511884
78TBX20_22080862_ChIP-Seq_HEART_Mouse1.04801373
79TBX20_22328084_ChIP-Seq_HEART_Mouse1.04801373
80BCAT_22108803_ChIP-Seq_LS180_Human1.02756896
81PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.02654760
82NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.01014265
83FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.00331863
84SMAD4_21741376_ChIP-Seq_HESCs_Human0.99622635
85CEBPB_22108803_ChIP-Seq_LS180_Human0.99290816
86SMAD3_21741376_ChIP-Seq_EPCs_Human0.99249501
87TDRD3_21172665_ChIP-Seq_MCF-7_Human0.98873890
88SALL4_18804426_ChIP-ChIP_XEN_Mouse0.98380328
89SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.96436547
90TCF4_18268006_ChIP-ChIP_LS174T_Human0.95856493
91* AR_21572438_ChIP-Seq_LNCaP_Human0.95728099
92HNFA_21074721_ChIP-Seq_CACO-2_Human0.95356413
93FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.95245179
94SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.94947031
95POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.94821449
96TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.93816323
97PKCTHETA_26484144_Chip-Seq_BREAST_Human0.93668895
98MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.92477939
99TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.92455427
100PHF8_20622853_ChIP-Seq_HELA_Human0.92381543
101SMRT_27268052_Chip-Seq_Bcells_Human0.92141321
102PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.91945515
103CDX2_20551321_ChIP-Seq_CACO-2_Human0.91862902
104RBPJ_21746931_ChIP-Seq_IB4_Human0.91821811
105SMC4_20622854_ChIP-Seq_HELA_Human0.91548307
106HNF4A_19822575_ChIP-Seq_HepG2_Human0.91512861
107CBX2_22325352_ChIP-Seq_293T-Rex_Human0.90879655
108WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.90238206
109RAD21_21589869_ChIP-Seq_MESCs_Mouse0.90069083
110CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.89843953
111RNF2_18974828_ChIP-Seq_MESCs_Mouse0.89290740
112EZH2_18974828_ChIP-Seq_MESCs_Mouse0.89290740
113EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.89017430
114FOXM1_26456572_ChIP-Seq_MCF-7_Human0.88479108
115SMAD4_21741376_ChIP-Seq_EPCs_Human0.88027648
116CTNNB1_20460455_ChIP-Seq_HCT116_Human0.87954946
117FOXA1_27270436_Chip-Seq_PROSTATE_Human0.87592720
118FOXA1_25329375_ChIP-Seq_VCAP_Human0.87592720
119STAT3_23295773_ChIP-Seq_U87_Human0.87211647
120CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.86314186
121VDR_24787735_ChIP-Seq_THP-1_Human0.86146588
122AR_25329375_ChIP-Seq_VCAP_Human0.85502569
123TCF4_23295773_ChIP-Seq_U87_Human0.85422874
124WT1_25993318_ChIP-Seq_PODOCYTE_Human0.85073390
125CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.84711179
126NRF2_20460467_ChIP-Seq_MEFs_Mouse0.81861644
127NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.81861644
128KDM2B_26808549_Chip-Seq_K562_Human0.81105272
129RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.80529086
130ATF3_27146783_Chip-Seq_COLON_Human0.80002950
131GATA6_25053715_ChIP-Seq_YYC3_Human0.79763116
132PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.79067566
133BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.78656373
134TP53_16413492_ChIP-PET_HCT116_Human0.78106358
135ZFP281_27345836_Chip-Seq_ESCs_Mouse0.78022921
136MTF2_20144788_ChIP-Seq_MESCs_Mouse0.77422795
137GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.76885792
138FOXA1_25552417_ChIP-Seq_VCAP_Human0.76884183
139* TCF4_22108803_ChIP-Seq_LS180_Human0.75085104
140KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.74306846
141ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.74100724
142GATA2_21666600_ChIP-Seq_HMVEC_Human0.74037500
143P300_27058665_Chip-Seq_ZR-75-30cells_Human0.73174118
144AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.73149458

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle6.63571662
2MP0008875_abnormal_xenobiotic_pharmacok4.91934524
3MP0004043_abnormal_pH_regulation4.86007339
4MP0002254_reproductive_system_inflammat4.29530533
5MP0002653_abnormal_ependyma_morphology4.09271599
6MP0003136_yellow_coat_color3.76991695
7MP0002796_impaired_skin_barrier3.61230917
8MP0002132_abnormal_respiratory_system3.41091092
9MP0000627_abnormal_mammary_gland3.24154246
10MP0001984_abnormal_olfaction2.97612855
11MP0003300_gastrointestinal_ulcer2.86128961
12MP0004264_abnormal_extraembryonic_tissu2.49531829
13MP0002098_abnormal_vibrissa_morphology2.43233248
14MP0003011_delayed_dark_adaptation2.34056355
15MP0003705_abnormal_hypodermis_morpholog2.32752857
16MP0005275_abnormal_skin_tensile2.31362259
17MP0003303_peritoneal_inflammation2.21819624
18MP0010678_abnormal_skin_adnexa2.21072671
19MP0002009_preneoplasia2.13263298
20MP0008789_abnormal_olfactory_epithelium2.10029018
21MP0004130_abnormal_muscle_cell2.09197892
22MP0005501_abnormal_skin_physiology2.07296288
23MP0001881_abnormal_mammary_gland10.2432442
24MP0004782_abnormal_surfactant_physiolog1.97314647
25MP0004019_abnormal_vitamin_homeostasis1.93408786
26MP0004147_increased_porphyrin_level1.86966278
27MP0002277_abnormal_respiratory_mucosa1.84874165
28MP0003941_abnormal_skin_development1.84080144
29MP0004133_heterotaxia1.83362834
30MP0000377_abnormal_hair_follicle1.73889972
31MP0008004_abnormal_stomach_pH1.72315111
32MP0005083_abnormal_biliary_tract1.69196832
33MP0003950_abnormal_plasma_membrane1.68693309
34MP0003566_abnormal_cell_adhesion1.66478977
35MP0000579_abnormal_nail_morphology1.59093481
36MP0001849_ear_inflammation1.56343138
37MP0001873_stomach_inflammation1.53974373
38MP0003453_abnormal_keratinocyte_physiol1.52744244
39MP0002060_abnormal_skin_morphology1.51615690
40MP0004272_abnormal_basement_membrane1.47463283
41MP0005666_abnormal_adipose_tissue1.44767451
42MP0004381_abnormal_hair_follicle1.37316354
43MP0005171_absent_coat_pigmentation1.36759631
44MP0010352_gastrointestinal_tract_polyps1.36188541
45MP0005365_abnormal_bile_salt1.33045434
46MP0001216_abnormal_epidermal_layer1.32318697
47MP0002160_abnormal_reproductive_system1.31703947
48MP0009384_cardiac_valve_regurgitation1.30726322
49MP0005623_abnormal_meninges_morphology1.29646712
50MP0002909_abnormal_adrenal_gland1.29392631
51MP0004185_abnormal_adipocyte_glucose1.29303872
52MP0002876_abnormal_thyroid_physiology1.28970095
53MP0009643_abnormal_urine_homeostasis1.24774833
54MP0003718_maternal_effect1.23402716
55MP0001756_abnormal_urination1.22916371
56MP0008438_abnormal_cutaneous_collagen1.20561284
57MP0005375_adipose_tissue_phenotype1.20414598
58MP0004885_abnormal_endolymph1.20395761
59MP0003045_fibrosis1.17616412
60MP0005499_abnormal_olfactory_system1.17362234
61MP0005394_taste/olfaction_phenotype1.17362234
62MP0005076_abnormal_cell_differentiation1.17266266
63MP0010771_integument_phenotype1.16834716
64MP0000383_abnormal_hair_follicle1.14885522
65MP0003656_abnormal_erythrocyte_physiolo1.14447413
66MP0002282_abnormal_trachea_morphology1.13617358
67MP0000427_abnormal_hair_cycle1.09312512
68MP0005395_other_phenotype1.06804478
69MP0000681_abnormal_thyroid_gland1.06302685
70MP0003890_abnormal_embryonic-extraembry1.04588159
71MP0000566_synostosis1.02675708
72MP0003936_abnormal_reproductive_system1.01834813
73MP0002136_abnormal_kidney_physiology1.00635658
74MP0005409_darkened_coat_color0.96228542
75MP0002139_abnormal_hepatobiliary_system0.95837368
76MP0002168_other_aberrant_phenotype0.94754077
77MP0002896_abnormal_bone_mineralization0.94645970
78MP0001485_abnormal_pinna_reflex0.94397449
79MP0000762_abnormal_tongue_morphology0.93802534
80MP0010329_abnormal_lipoprotein_level0.92301174
81MP0005670_abnormal_white_adipose0.91568742
82MP0009379_abnormal_foot_pigmentation0.90201170
83MP0002118_abnormal_lipid_homeostasis0.88576906
84MP0002233_abnormal_nose_morphology0.88113818
85MP0005360_urolithiasis0.86732495
86MP0003252_abnormal_bile_duct0.82743571
87MP0005408_hypopigmentation0.82678305
88MP0004947_skin_inflammation0.82188350
89MP0001324_abnormal_eye_pigmentation0.81009084
90MP0001177_atelectasis0.79370940
91MP0000678_abnormal_parathyroid_gland0.78510688
92MP0005248_abnormal_Harderian_gland0.78029794
93MP0000003_abnormal_adipose_tissue0.77611337
94MP0005389_reproductive_system_phenotype0.76766857
95MP0000647_abnormal_sebaceous_gland0.76709189
96MP0001664_abnormal_digestion0.76257612
97MP0005023_abnormal_wound_healing0.72579330
98MP0009703_decreased_birth_body0.71361915
99MP0005647_abnormal_sex_gland0.70709455
100MP0000467_abnormal_esophagus_morphology0.70596756
101MP0009931_abnormal_skin_appearance0.70123139
102MP0005085_abnormal_gallbladder_physiolo0.70038810
103MP0005646_abnormal_pituitary_gland0.69583014
104MP0001346_abnormal_lacrimal_gland0.68263467
105MP0001666_abnormal_nutrient_absorption0.68111588
106MP0002166_altered_tumor_susceptibility0.67226633
107MP0008770_decreased_survivor_rate0.66687929
108MP0005377_hearing/vestibular/ear_phenot0.66632543
109MP0003878_abnormal_ear_physiology0.66632543
110MP0003448_altered_tumor_morphology0.66171966
111MP0009780_abnormal_chondrocyte_physiolo0.66121148
112MP0001293_anophthalmia0.65641656
113MP0001663_abnormal_digestive_system0.65225710
114MP0001270_distended_abdomen0.64587937
115MP0005334_abnormal_fat_pad0.62608411
116MP0002971_abnormal_brown_adipose0.61448784
117MP0000750_abnormal_muscle_regeneration0.61229624
118MP0001851_eye_inflammation0.60302526
119MP0009278_abnormal_bone_marrow0.59800920
120MP0005332_abnormal_amino_acid0.56282411
121MP0002970_abnormal_white_adipose0.56212533
122MP0005381_digestive/alimentary_phenotyp0.55355434
123MP0003075_altered_response_to0.54604573
124MP0005220_abnormal_exocrine_pancreas0.53951796
125MP0000639_abnormal_adrenal_gland0.53423955
126MP0000367_abnormal_coat/_hair0.52997208
127MP0003943_abnormal_hepatobiliary_system0.52995974
128MP0004742_abnormal_vestibular_system0.52234807
129MP0002135_abnormal_kidney_morphology0.51770399
130MP0003879_abnormal_hair_cell0.51410967
131MP0001188_hyperpigmentation0.51175064
132MP0001765_abnormal_ion_homeostasis0.50683661
133MP0004858_abnormal_nervous_system0.50357255
134MP0000163_abnormal_cartilage_morphology0.49540065
135MP0005636_abnormal_mineral_homeostasis0.48640650
136MP0003195_calcinosis0.47765153
137MP0003698_abnormal_male_reproductive0.46780270
138MP0010368_abnormal_lymphatic_system0.46585804
139MP0003122_maternal_imprinting0.44347054
140MP0005164_abnormal_response_to0.44246788
141MP0002933_joint_inflammation0.43852896
142MP0003937_abnormal_limbs/digits/tail_de0.43475682
143MP0003948_abnormal_gas_homeostasis0.43193549
144MP0002877_abnormal_melanocyte_morpholog0.42869790
145MP0002006_tumorigenesis0.42809244
146MP0005075_abnormal_melanosome_morpholog0.42526589
147MP0001191_abnormal_skin_condition0.42005506
148MP0000858_altered_metastatic_potential0.41261412

Predicted human phenotypes

RankGene SetZ-score
1Dynein arm defect of respiratory motile cilia (HP:0012255)9.82148464
2Absent/shortened dynein arms (HP:0200106)9.82148464
3Abnormal respiratory motile cilium physiology (HP:0012261)9.80826975
4Abnormal ciliary motility (HP:0012262)9.66134740
5Rhinitis (HP:0012384)9.00733328
6Chronic bronchitis (HP:0004469)7.44556267
7Bronchiectasis (HP:0002110)6.68073992
8Nasal polyposis (HP:0100582)5.66448685
9Right ventricular cardiomyopathy (HP:0011663)5.66088406
10Pili torti (HP:0003777)5.51288488
11Congenital ichthyosiform erythroderma (HP:0007431)5.35745201
12Amelogenesis imperfecta (HP:0000705)4.98098625
13Abnormality of the nasal mucosa (HP:0000433)4.61257328
14Hyperactive renin-angiotensin system (HP:0000841)4.59768792
15Onycholysis (HP:0001806)4.36192159
16Curly hair (HP:0002212)4.16850069
17Recurrent sinusitis (HP:0011108)4.15443722
18Bronchitis (HP:0012387)4.04339057
19Abnormality of purine metabolism (HP:0004352)3.99002681
20Milia (HP:0001056)3.97701958
21Enlarged epiphyses (HP:0010580)3.93091263
22Overgrowth (HP:0001548)3.87774208
23Atrophic scars (HP:0001075)3.77479448
24Epiphyseal dysplasia (HP:0002656)3.72404998
25Recurrent otitis media (HP:0000403)3.67471237
26Ectropion (HP:0000656)3.66375975
27Infertility (HP:0000789)3.56331673
28Thin bony cortex (HP:0002753)3.52617722
29Abnormality of nail color (HP:0100643)3.49127350
30Male infertility (HP:0003251)3.48365098
31Chronic sinusitis (HP:0011109)3.33312732
32Occipital encephalocele (HP:0002085)3.28934996
33Axonal loss (HP:0003447)3.26932408
34Hypoplasia of the iris (HP:0007676)3.20514743
35Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.19642859
36Subcapsular cataract (HP:0000523)3.18082930
37Abnormal hair laboratory examination (HP:0003328)3.17113430
38True hermaphroditism (HP:0010459)3.16871750
39Abnormality of calcium-phosphate metabolism (HP:0100530)3.16648751
40Hypoplasia of dental enamel (HP:0006297)3.08346437
41Pancreatic fibrosis (HP:0100732)3.03934420
42Protuberant abdomen (HP:0001538)2.99506723
43Renal salt wasting (HP:0000127)2.99285557
44Hypokalemic alkalosis (HP:0001949)2.97170636
45Nephritis (HP:0000123)2.96907656
46Fragile nails (HP:0001808)2.93707943
47Gout (HP:0001997)2.91400766
48Aplasia cutis congenita (HP:0001057)2.90545897
49Alopecia of scalp (HP:0002293)2.85851786
50Sparse lateral eyebrow (HP:0005338)2.77856408
51Lip pit (HP:0100267)2.77032170
52Hypotrichosis (HP:0001006)2.72330520
53Hyperaldosteronism (HP:0000859)2.71372114
54Plantar hyperkeratosis (HP:0007556)2.70670070
55Woolly hair (HP:0002224)2.66428997
56Pancreatic cysts (HP:0001737)2.65430022
57Cystic liver disease (HP:0006706)2.64551134
58Abnormal auditory evoked potentials (HP:0006958)2.64415045
59Abnormality of chloride homeostasis (HP:0011422)2.62546668
60Turricephaly (HP:0000262)2.62445418
61Biliary tract neoplasm (HP:0100574)2.51883778
62Abnormality of renal resorption (HP:0011038)2.51204112
63Glomerulosclerosis (HP:0000096)2.50900564
64Abnormality of midbrain morphology (HP:0002418)2.50262891
65Molar tooth sign on MRI (HP:0002419)2.50262891
66Severe Myopia (HP:0011003)2.50204277
67Chronic hepatic failure (HP:0100626)2.49445201
68Chronic otitis media (HP:0000389)2.47441513
69Morphological abnormality of the inner ear (HP:0011390)2.46202102
70Shallow orbits (HP:0000586)2.44752843
71Abnormality of renin-angiotensin system (HP:0000847)2.43589868
72Abnormality of the dental pulp (HP:0006479)2.41732597
73Nephronophthisis (HP:0000090)2.40058321
74Nail dystrophy (HP:0008404)2.39543689
75Arterial tortuosity (HP:0005116)2.39496220
76Atelectasis (HP:0100750)2.38888868
77Erythroderma (HP:0001019)2.38215349
78Abnormality of renal excretion (HP:0011036)2.37164661
79Exostoses (HP:0100777)2.35646343
80White forelock (HP:0002211)2.35586089
81Polar cataract (HP:0010696)2.34512413
82Germ cell neoplasia (HP:0100728)2.31559377
83Buphthalmos (HP:0000557)2.27929616
84Aortic dissection (HP:0002647)2.27502382
85Aortic aneurysm (HP:0004942)2.25620121
86Abnormality of the anterior chamber (HP:0000593)2.25000807
87Renal tubular acidosis (HP:0001947)2.24878485
88Vascular calcification (HP:0004934)2.24848376
89Advanced eruption of teeth (HP:0006288)2.24111307
90Abdominal distention (HP:0003270)2.23134547
91Stridor (HP:0010307)2.22328412
92Abnormal hemoglobin (HP:0011902)2.21695350
93Metaphyseal dysplasia (HP:0100255)2.19945521
94Hypohidrosis (HP:0000966)2.19549240
95Cardiovascular calcification (HP:0011915)2.18995643
96Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.18943513
97Abnormality of the renal medulla (HP:0100957)2.16690451
98Postaxial foot polydactyly (HP:0001830)2.16581714
99Decreased circulating renin level (HP:0003351)2.15938919
100Cerebral aneurysm (HP:0004944)2.14895916
101Bone cyst (HP:0012062)2.14595837
102Enlarged penis (HP:0000040)2.12893448
103Premature skin wrinkling (HP:0100678)2.12007992
104Abnormality of permanent molar morphology (HP:0011071)2.11486391
105Abnormality of the dental root (HP:0006486)2.11486391
106Taurodontia (HP:0000679)2.11486391
107Absent eyelashes (HP:0000561)2.10922192
108Vascular tortuosity (HP:0004948)2.09224126
109Abnormality of nucleobase metabolism (HP:0010932)2.05734273
110Tubular atrophy (HP:0000092)2.03709013
111Widely patent fontanelles and sutures (HP:0004492)2.02517066
112Furrowed tongue (HP:0000221)2.02195875
113Hyperkalemia (HP:0002153)2.00268971
114Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.2141525
115Abnormal respiratory epithelium morphology (HP:0012253)10.0207094
116Abnormal respiratory motile cilium morphology (HP:0005938)10.0207094
117Peripheral hypomyelination (HP:0007182)1.99730213
118Aneurysm (HP:0002617)1.98675089
119Fragile skin (HP:0001030)1.98650722
120Anterior segment dysgenesis (HP:0007700)1.98382679
121Concave nail (HP:0001598)1.98277593
122Acanthosis nigricans (HP:0000956)1.98072154
123Blepharitis (HP:0000498)1.96971994
124Asymmetry of the thorax (HP:0001555)1.95341282
125Patchy hypopigmentation of hair (HP:0011365)1.94951987
126Long toe (HP:0010511)1.94462314
127Increased circulating renin level (HP:0000848)1.94304204
128Abnormality of molar (HP:0011077)1.93607835
129Abnormality of molar morphology (HP:0011070)1.93607835
130Tubulointerstitial fibrosis (HP:0005576)1.90664402
131Increased IgE level (HP:0003212)1.89953370
132Abnormality of dental color (HP:0011073)1.88753918
133Bell-shaped thorax (HP:0001591)1.88663446
134Hemorrhage of the eye (HP:0011885)1.88042113
135Nephrolithiasis (HP:0000787)1.86342542
136Urethral obstruction (HP:0000796)1.86215830
137Hyperparathyroidism (HP:0000843)1.83369251
138Tubulointerstitial nephritis (HP:0001970)1.82781054
139Pterygium (HP:0001059)1.81993263
140Premature loss of primary teeth (HP:0006323)1.81978655
141Parakeratosis (HP:0001036)1.81895680
142Congenital hepatic fibrosis (HP:0002612)1.80867805
143Aplasia/Hypoplasia of the tongue (HP:0010295)1.76930986
144Abnormality of the salivary glands (HP:0010286)1.76833144
145Corneal erosion (HP:0200020)1.74363373
146Male pseudohermaphroditism (HP:0000037)1.73819529
147Polydipsia (HP:0001959)1.73376312
148Abnormal drinking behavior (HP:0030082)1.73376312
149Autoamputation (HP:0001218)1.72904892
150Rectal prolapse (HP:0002035)1.72464135
151Alacrima (HP:0000522)1.72417769
152Recurrent bronchitis (HP:0002837)1.70439726
153Palmoplantar hyperkeratosis (HP:0000972)1.68225839
154Heterochromia iridis (HP:0001100)1.67190049
155Polyuria (HP:0000103)1.61547356
156Anencephaly (HP:0002323)1.59336517
157Nephropathy (HP:0000112)1.58799104
158Abnormality of sodium homeostasis (HP:0010931)1.55327069
159Hyponatremia (HP:0002902)1.52700010
160Aplasia/Hypoplasia of the spleen (HP:0010451)1.52682065
161Palmar hyperkeratosis (HP:0010765)1.52495669
162Cone-rod dystrophy (HP:0000548)1.51363263
163Medial flaring of the eyebrow (HP:0010747)1.48392130
164Abnormality of macular pigmentation (HP:0008002)1.48070869
165Asplenia (HP:0001746)1.45802005
166Bifid scrotum (HP:0000048)1.45737481
167Abnormal urine output (HP:0012590)1.44268098
168Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.40469250
169Oculomotor apraxia (HP:0000657)1.40260645
170Congenital primary aphakia (HP:0007707)1.36613135
171Short thorax (HP:0010306)1.35580199
172Postaxial hand polydactyly (HP:0001162)1.35525441
173Median cleft lip (HP:0000161)1.33995931
174Nephrogenic diabetes insipidus (HP:0009806)1.31924330
175Flat acetabular roof (HP:0003180)1.31658513
176Abnormality of monocarboxylic acid metabolism (HP:0010996)1.31404589
177Alkalosis (HP:0001948)1.31157671
178Decreased central vision (HP:0007663)1.30351111
179Adrenal overactivity (HP:0002717)1.29121742
180Gait imbalance (HP:0002141)1.28936297
181Tubulointerstitial abnormality (HP:0001969)1.27836995
182Abnormality of the frontal sinuses (HP:0002687)1.26318649
183Hypomagnesemia (HP:0002917)1.25677171

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK157.55482529
2SIK17.17819038
3CAMK1D4.24773686
4PKN23.86037322
5CAMK1G3.49979764
6TRIB33.13008249
7NME12.83231351
8NME22.69652622
9LATS12.69263006
10PIK3CA2.51447810
11EPHA32.51203121
12EEF2K2.50797314
13OXSR12.49374829
14EPHB12.44723869
15STK242.44111794
16FER2.39383336
17MATK2.29529873
18ERN12.26070329
19DDR22.21554117
20WNK32.19660633
21PTK62.13003031
22PDK42.03534017
23PDK32.03534017
24RIPK11.71618817
25DAPK21.57905443
26EPHA21.52663463
27STK391.45257628
28PDGFRB1.39280266
29RET1.38850414
30PDK21.37344647
31BRSK21.36614744
32TTK1.29353892
33MAPKAPK31.27176165
34MAP3K21.25436239
35ERBB31.21667949
36NEK61.19609602
37WNK41.19521416
38BMX1.19201685
39ICK1.18531742
40TRPM71.16335963
41STK38L1.11930086
42STK381.11234108
43LRRK21.10188419
44AKT31.08848680
45FGFR41.07841672
46FRK1.07710095
47MAP3K71.07169261
48RPS6KB21.05295761
49BCKDK1.03679957
50TGFBR21.01096644
51SGK21.00448351
52CSK0.95779206
53PRKAA20.90875016
54FGFR30.88776541
55PTK2B0.88012955
56PRKCI0.82394336
57PTK20.81941461
58MET0.76539145
59STK100.76383801
60MST1R0.75910341
61FGFR20.75796294
62SGK30.72526657
63GRK10.69330109
64MAP3K120.65720979
65MAP3K40.64591575
66CDK60.62962096
67MST40.61684601
68LATS20.61071745
69STK30.60714617
70JAK10.59922348
71ERBB20.59659355
72RPS6KA20.58049326
73MAP3K30.57411126
74GSK3A0.57368345
75ZAP700.57271708
76JAK20.56371488
77NLK0.56321917
78MARK20.56017362
79EIF2AK10.53952258
80PDGFRA0.52265071
81CAMK10.51888402
82SGK10.51352069
83MAP4K20.51345554
84FGFR10.51164731
85EIF2AK30.49132347
86CDK120.45491841
87IGF1R0.44170809
88MAP3K60.43294180
89CHUK0.41541523
90SMG10.41187810
91LMTK20.40252604
92PRKD10.39744762
93BRD40.38523852
94MAP3K10.37214119
95PRKAA10.36824882
96MTOR0.36614543
97TGFBR10.35444763
98ABL10.34979418
99JAK30.33784389
100CSNK1A10.33463276
101INSRR0.33450155
102DYRK1B0.33197620
103PRKCD0.32615876
104WNK10.31419151
105IRAK10.31153274
106EPHB20.29282065
107SRC0.29058906
108MAP2K10.29035445
109TBK10.28392422
110FLT30.28181611
111MAPKAPK50.27815580
112BMPR1B0.27132382
113PDPK10.26995085
114MAPK120.26852401
115BCR0.26759359
116MAP2K60.26557307
117PRKCQ0.26239645
118MAPK110.25872845
119TTN0.25587861
120SGK2230.25513209
121SGK4940.25513209
122PRKCZ0.24514962
123TYRO30.24295543
124PAK20.23838277
125PAK30.23798098
126INSR0.23155426
127PRKCE0.22969258
128PBK0.22170103
129PDK10.21114137
130PRKCA0.20869277
131EGFR0.20849322
132RPS6KL10.20842061
133RPS6KC10.20842061
134ADRBK20.20582769
135HIPK20.20582225
136CAMK2G0.20071669
137FGR0.19760313
138TLK10.18857683
139MYLK0.18842188
140RPS6KA10.17149369
141PRKACA0.17119653
142RPS6KB10.16750225
143CSF1R0.16525092
144YES10.16234435
145CSNK1E0.16037422
146ACVR1B0.15632057
147AKT20.15620590
148PIK3CG0.15486885
149CDK90.14970428
150PAK40.14475413

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000618.66795053
2Caffeine metabolism_Homo sapiens_hsa002327.73063202
3Histidine metabolism_Homo sapiens_hsa003404.51382987
4Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009804.02467459
5Drug metabolism - cytochrome P450_Homo sapiens_hsa009823.35158286
6Chemical carcinogenesis_Homo sapiens_hsa052043.33844448
7Tyrosine metabolism_Homo sapiens_hsa003502.95097829
8Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.77158282
9Galactose metabolism_Homo sapiens_hsa000522.62214347
10Fatty acid metabolism_Homo sapiens_hsa012122.47951495
11Prolactin signaling pathway_Homo sapiens_hsa049172.17563026
12Steroid hormone biosynthesis_Homo sapiens_hsa001402.12734813
13Linoleic acid metabolism_Homo sapiens_hsa005912.12041050
14Retinol metabolism_Homo sapiens_hsa008302.10755216
15Sphingolipid metabolism_Homo sapiens_hsa006002.03730588
16Glutathione metabolism_Homo sapiens_hsa004801.87190734
17Complement and coagulation cascades_Homo sapiens_hsa046101.81733988
18Propanoate metabolism_Homo sapiens_hsa006401.81568097
19Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.80480391
20Pyruvate metabolism_Homo sapiens_hsa006201.64862250
21PPAR signaling pathway_Homo sapiens_hsa033201.63324903
22Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.53509949
23ABC transporters_Homo sapiens_hsa020101.48687994
24Collecting duct acid secretion_Homo sapiens_hsa049661.40662907
25Pentose and glucuronate interconversions_Homo sapiens_hsa000401.39160049
26Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.32715462
27Circadian rhythm_Homo sapiens_hsa047101.29063180
28Arachidonic acid metabolism_Homo sapiens_hsa005901.25464373
29Vitamin digestion and absorption_Homo sapiens_hsa049771.24994862
30Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.19933179
31Cyanoamino acid metabolism_Homo sapiens_hsa004601.19319651
32Starch and sucrose metabolism_Homo sapiens_hsa005001.11455684
33ECM-receptor interaction_Homo sapiens_hsa045121.04910680
34Fatty acid elongation_Homo sapiens_hsa000621.04580069
35Huntingtons disease_Homo sapiens_hsa050161.02169458
36Primary bile acid biosynthesis_Homo sapiens_hsa001201.01437462
37Insulin resistance_Homo sapiens_hsa049311.00862272
38Vibrio cholerae infection_Homo sapiens_hsa051101.00230792
39Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.00215107
40Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.99640210
41Adherens junction_Homo sapiens_hsa045200.98845919
42Ether lipid metabolism_Homo sapiens_hsa005650.98742361
43Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.97858221
44Fatty acid degradation_Homo sapiens_hsa000710.94696624
45Ovarian steroidogenesis_Homo sapiens_hsa049130.94170339
46Adipocytokine signaling pathway_Homo sapiens_hsa049200.91910468
47AMPK signaling pathway_Homo sapiens_hsa041520.90112271
48Hedgehog signaling pathway_Homo sapiens_hsa043400.89507442
49Pancreatic cancer_Homo sapiens_hsa052120.87172970
50Nitrogen metabolism_Homo sapiens_hsa009100.85526289
51Arginine and proline metabolism_Homo sapiens_hsa003300.83533951
52Tight junction_Homo sapiens_hsa045300.80796448
53N-Glycan biosynthesis_Homo sapiens_hsa005100.80563228
54Drug metabolism - other enzymes_Homo sapiens_hsa009830.79795343
55Glycerophospholipid metabolism_Homo sapiens_hsa005640.79786779
56Bladder cancer_Homo sapiens_hsa052190.79445189
57Amoebiasis_Homo sapiens_hsa051460.79433131
58Choline metabolism in cancer_Homo sapiens_hsa052310.77950210
59Thyroid hormone synthesis_Homo sapiens_hsa049180.76188971
60Tryptophan metabolism_Homo sapiens_hsa003800.75127517
61Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.72758099
62Hippo signaling pathway_Homo sapiens_hsa043900.72062412
63Acute myeloid leukemia_Homo sapiens_hsa052210.69077837
64Proteoglycans in cancer_Homo sapiens_hsa052050.68315831
65Focal adhesion_Homo sapiens_hsa045100.68086024
66Endometrial cancer_Homo sapiens_hsa052130.67651235
67Rheumatoid arthritis_Homo sapiens_hsa053230.66473516
68Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.64918804
69Central carbon metabolism in cancer_Homo sapiens_hsa052300.64906404
70Steroid biosynthesis_Homo sapiens_hsa001000.64878093
71Toxoplasmosis_Homo sapiens_hsa051450.64190348
72Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.61646501
73Chronic myeloid leukemia_Homo sapiens_hsa052200.61568224
74Small cell lung cancer_Homo sapiens_hsa052220.60613345
75Arginine biosynthesis_Homo sapiens_hsa002200.57767391
76Basal cell carcinoma_Homo sapiens_hsa052170.57715896
77Fat digestion and absorption_Homo sapiens_hsa049750.57367856
78alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.56585017
79Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.55906676
80Insulin signaling pathway_Homo sapiens_hsa049100.54772307
81Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.54726545
82Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.53450564
83Leukocyte transendothelial migration_Homo sapiens_hsa046700.52375501
84Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.52278734
85AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.52223645
86Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.51523576
87Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.51434976
88ErbB signaling pathway_Homo sapiens_hsa040120.50379320
89Glycerolipid metabolism_Homo sapiens_hsa005610.49609035
90Hepatitis C_Homo sapiens_hsa051600.49419448
91Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.49138084
92mTOR signaling pathway_Homo sapiens_hsa041500.48185786
93Phototransduction_Homo sapiens_hsa047440.47892008
94Glycosaminoglycan degradation_Homo sapiens_hsa005310.47560466
95Pentose phosphate pathway_Homo sapiens_hsa000300.46793749
96Butanoate metabolism_Homo sapiens_hsa006500.46536430
97Carbon metabolism_Homo sapiens_hsa012000.44607542
98Gastric acid secretion_Homo sapiens_hsa049710.44265700
99Renal cell carcinoma_Homo sapiens_hsa052110.44148812
100Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.43923016
101Metabolic pathways_Homo sapiens_hsa011000.42293332
102Peroxisome_Homo sapiens_hsa041460.41902774
103Colorectal cancer_Homo sapiens_hsa052100.41766282
104Taste transduction_Homo sapiens_hsa047420.40929020
105Protein digestion and absorption_Homo sapiens_hsa049740.40742551
1062-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.40088474
107Synaptic vesicle cycle_Homo sapiens_hsa047210.39818247
108Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.39242197
109Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.39092168
110Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.38413231
111Staphylococcus aureus infection_Homo sapiens_hsa051500.38065365
112Glucagon signaling pathway_Homo sapiens_hsa049220.37885360
113VEGF signaling pathway_Homo sapiens_hsa043700.36758233
114Sulfur metabolism_Homo sapiens_hsa009200.36715362
115Thyroid cancer_Homo sapiens_hsa052160.35597221
116Maturity onset diabetes of the young_Homo sapiens_hsa049500.35142949
117Melanogenesis_Homo sapiens_hsa049160.34382109
118Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.32945239
119Dorso-ventral axis formation_Homo sapiens_hsa043200.32918813
120HIF-1 signaling pathway_Homo sapiens_hsa040660.32473222
121Melanoma_Homo sapiens_hsa052180.31878354
122Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.31076695
123Protein export_Homo sapiens_hsa030600.31006606
124Carbohydrate digestion and absorption_Homo sapiens_hsa049730.30965476
125Prostate cancer_Homo sapiens_hsa052150.30761716
126Bile secretion_Homo sapiens_hsa049760.30571942
127Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.30383809
128Mineral absorption_Homo sapiens_hsa049780.30128090
129Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.30000866
130Endocytosis_Homo sapiens_hsa041440.29542160
131Longevity regulating pathway - mammal_Homo sapiens_hsa042110.29396542
132Non-small cell lung cancer_Homo sapiens_hsa052230.28492116
133Phenylalanine metabolism_Homo sapiens_hsa003600.27760438
134Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.27606229
135Olfactory transduction_Homo sapiens_hsa047400.27240062
136Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.26688621
137Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.26479825
138Phagosome_Homo sapiens_hsa041450.26402923
139Toll-like receptor signaling pathway_Homo sapiens_hsa046200.25551350
140Renin secretion_Homo sapiens_hsa049240.25445343
141MicroRNAs in cancer_Homo sapiens_hsa052060.24438222
142Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.24292152
143TGF-beta signaling pathway_Homo sapiens_hsa043500.22833693
144Estrogen signaling pathway_Homo sapiens_hsa049150.22717189
145Phosphatidylinositol signaling system_Homo sapiens_hsa040700.22134109
146Salivary secretion_Homo sapiens_hsa049700.21258598
147beta-Alanine metabolism_Homo sapiens_hsa004100.20722606
148Pathways in cancer_Homo sapiens_hsa052000.20656668
149Sulfur relay system_Homo sapiens_hsa041220.20412578
150Lysosome_Homo sapiens_hsa041420.20138936
151Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.16987141
152Jak-STAT signaling pathway_Homo sapiens_hsa046300.15261480
153Serotonergic synapse_Homo sapiens_hsa047260.13601522
154Sphingolipid signaling pathway_Homo sapiens_hsa040710.13183401
155Wnt signaling pathway_Homo sapiens_hsa043100.08815384
156Transcriptional misregulation in cancer_Homo sapiens_hsa052020.08593692

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